## Wed Oct 16 00:38:43 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/GDHHQS3_bin.65.fa -m mmseqs --itype genome -o GDHHQS3_bin.65 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/GDHHQS3_bin.65 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS3_k127_1081576_71	380394.Lferr_2248	8.08e-05	55.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,2NC7F@225057|Acidithiobacillales	225057|Acidithiobacillales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_1081576_19	1191523.MROS_2033	2.991e-88	323.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_1081576_9	886293.Sinac_2284	3.998e-111	394.0	COG1034@1|root,COG1034@2|Bacteria,2IY04@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2,Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GDHHQS3_k127_1081576_3	716928.AJQT01000068_gene3401	1.132e-152	496.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2U2JT@28211|Alphaproteobacteria,4BB5D@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF2	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_1081576_40	1260251.SPISAL_03115	4.685e-37	152.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS3_k127_1081576_50	159450.NH14_30160	2.091e-25	109.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,1K7MQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS3_k127_1081576_42	697282.Mettu_3252	1.812e-36	146.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_1081576_46	243231.GSU0246	7.983e-30	132.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42WVX@68525|delta/epsilon subdivisions,2X5M2@28221|Deltaproteobacteria,43W2Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
GDHHQS3_k127_1081576_32	1323663.AROI01000009_gene3630	1.348e-54	203.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710	adh_short_C2
GDHHQS3_k127_1081576_62	1121920.AUAU01000008_gene1666	1.529e-16	83.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_1081576_75	574375.BAGA_12585	0.0002876	48.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,1ZFJ9@1386|Bacillus	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS3_k127_1081576_73	269799.Gmet_0593	0.0001853	53.0	28TYD@1|root,2ZG50@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_14	471852.Tcur_2826	2.852e-100	350.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4EFNS@85012|Streptosporangiales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
GDHHQS3_k127_1081576_63	1267533.KB906740_gene246	9.94e-16	83.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria,2JJNQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS3_k127_1081576_43	1128421.JAGA01000002_gene939	3.668e-36	147.0	COG4221@1|root,COG4221@2|Bacteria,2NRJZ@2323|unclassified Bacteria	2|Bacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_1081576_60	1365176.N186_07050	7.285e-20	104.0	arCOG14774@1|root,arCOG14774@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_38	525146.Ddes_1621	4.811e-40	154.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MB4E@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GDHHQS3_k127_1081576_53	767817.Desgi_2610	2.24e-24	115.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,26201@186807|Peptococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS3_k127_1081576_67	398767.Glov_1902	6.458e-10	72.0	COG1305@1|root,COG1305@2|Bacteria,1Q1D3@1224|Proteobacteria,43772@68525|delta/epsilon subdivisions,2WSIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GDHHQS3_k127_1081576_0	1089553.Tph_c21390	4.588e-283	911.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_1081576_56	1047013.AQSP01000135_gene1588	3.132e-21	103.0	COG2980@1|root,COG2980@2|Bacteria	2|Bacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
GDHHQS3_k127_1081576_76	550540.Fbal_1832	0.0003546	51.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1SYEH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	Pkinase
GDHHQS3_k127_1081576_68	379066.GAU_1519	1.178e-08	61.0	COG0268@1|root,COG0268@2|Bacteria,1ZU6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS3_k127_1081576_49	1121405.dsmv_2433	2.402e-26	124.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
GDHHQS3_k127_1081576_44	290315.Clim_0749	2.232e-33	137.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GDHHQS3_k127_1081576_24	1047013.AQSP01000135_gene1613	5.899e-76	271.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GDHHQS3_k127_1081576_69	1121413.JMKT01000017_gene450	5.37e-08	63.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2WSJJ@28221|Deltaproteobacteria,2M7R0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
GDHHQS3_k127_1081576_48	338963.Pcar_2977	2.633e-27	123.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,43SME@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_1081576_36	1121920.AUAU01000023_gene2424	4.343e-47	186.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
GDHHQS3_k127_1081576_30	234267.Acid_1166	2.075e-59	215.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS3_k127_1081576_26	234267.Acid_1165	1.12e-72	268.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS3_k127_1081576_35	1267535.KB906767_gene5001	4.111e-50	205.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GDHHQS3_k127_1081576_45	1125863.JAFN01000001_gene1084	6.349e-32	136.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2WWFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
GDHHQS3_k127_1081576_2	665956.HMPREF1032_01597	5.88e-164	528.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS3_k127_1081576_5	1382306.JNIM01000001_gene3872	1.688e-145	481.0	COG1387@1|root,COG1387@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GDHHQS3_k127_1081576_17	1519464.HY22_07445	2.039e-91	335.0	COG1252@1|root,COG1252@2|Bacteria,1FEPV@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_1081576_12	1382359.JIAL01000001_gene1923	9.358e-103	363.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
GDHHQS3_k127_1081576_47	379066.GAU_2460	1.305e-29	123.0	COG0720@1|root,COG0720@2|Bacteria,1ZTRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_1081576_39	671143.DAMO_1375	4.823e-40	155.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
GDHHQS3_k127_1081576_20	1047013.AQSP01000134_gene1378	3.035e-81	277.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_1081576_31	1047013.AQSP01000134_gene1379	4.121e-57	209.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS3_k127_1081576_8	880072.Desac_1935	1.85e-111	371.0	COG2006@1|root,COG2006@2|Bacteria,1R7BH@1224|Proteobacteria,42QGJ@68525|delta/epsilon subdivisions,2WJ1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GDHHQS3_k127_1081576_34	1304872.JAGC01000009_gene305	3.272e-51	207.0	COG1657@1|root,COG1657@2|Bacteria,1RGS3@1224|Proteobacteria,42S9E@68525|delta/epsilon subdivisions,2WNMZ@28221|Deltaproteobacteria,2MA94@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_1	671143.DAMO_0012	4.997e-206	655.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
GDHHQS3_k127_1081576_6	1121957.ATVL01000011_gene3883	1.04e-135	471.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47JF7@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
GDHHQS3_k127_1081576_4	913325.N799_06400	2.166e-149	488.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1X37F@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
GDHHQS3_k127_1081576_54	399739.Pmen_1194	2.11e-23	106.0	2CD2E@1|root,330VS@2|Bacteria,1N86R@1224|Proteobacteria,1SE64@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
GDHHQS3_k127_1081576_21	234267.Acid_2317	7.217e-81	280.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
GDHHQS3_k127_1081576_52	1248916.ANFY01000003_gene750	1.976e-24	110.0	COG2105@1|root,COG2105@2|Bacteria,1N814@1224|Proteobacteria,2UCQF@28211|Alphaproteobacteria,2KB1D@204457|Sphingomonadales	204457|Sphingomonadales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
GDHHQS3_k127_1081576_57	1236959.BAMT01000008_gene2542	3.394e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,1N9ZK@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GDHHQS3_k127_1081576_72	1122915.AUGY01000012_gene3916	0.0001223	53.0	arCOG13956@1|root,33BWW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_16	338963.Pcar_0596	3.562e-99	364.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,43S0N@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_1081576_28	204669.Acid345_2395	3.076e-62	240.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_1081576_15	909663.KI867151_gene3132	4.246e-100	358.0	COG0774@1|root,COG2204@1|root,COG0774@2|Bacteria,COG2204@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MRFZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	MT	UDP-3-O-acyl N-acetylglycosamine deacetylase	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
GDHHQS3_k127_1081576_22	1266845.Q783_05295	2.05e-80	280.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,27FRT@186828|Carnobacteriaceae	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GDHHQS3_k127_1081576_33	525904.Tter_0015	1.627e-54	212.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_1081576_55	682795.AciX8_3673	1.266e-21	100.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS3_k127_1081576_13	234267.Acid_7711	1.639e-100	338.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GDHHQS3_k127_1081576_10	316274.Haur_1203	6.186e-109	359.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS3_k127_1081576_59	1337936.IJ00_05665	1.04e-20	108.0	COG0802@1|root,COG0802@2|Bacteria,1G6ZV@1117|Cyanobacteria,1HNBP@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised P-loop hydrolase UPF0079	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GDHHQS3_k127_1081576_11	429009.Adeg_1759	4.136e-108	372.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
GDHHQS3_k127_1081576_51	443143.GM18_4140	2.143e-25	115.0	COG3222@1|root,COG3222@2|Bacteria,1RHCP@1224|Proteobacteria,43B9I@68525|delta/epsilon subdivisions,2X6NN@28221|Deltaproteobacteria,43SK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Guanylyl transferase CofC like	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
GDHHQS3_k127_1081576_74	1122927.KB895415_gene4386	0.0002115	47.0	2C95S@1|root,33HPC@2|Bacteria,1VJZ1@1239|Firmicutes,4I8KU@91061|Bacilli,2703Y@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
GDHHQS3_k127_1081576_77	211114.JOEF01000003_gene3151	0.000579	49.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4E4BG@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
GDHHQS3_k127_1081576_58	639030.JHVA01000001_gene1597	6.671e-21	110.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_65	234267.Acid_2620	1.455e-12	81.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_23	861299.J421_2808	3.297e-78	286.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GDHHQS3_k127_1081576_29	1128421.JAGA01000002_gene1501	8.604e-62	234.0	COG0351@1|root,COG0351@2|Bacteria,2NP3M@2323|unclassified Bacteria	2|Bacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00868,ko:K00941,ko:K03147,ko:K21219	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS03115	Phos_pyr_kin
GDHHQS3_k127_1081576_37	861299.J421_2559	2.224e-42	166.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_1081576_18	485915.Dret_0471	1.081e-90	315.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2M94B@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_1081576_70	215803.DB30_5217	1.414e-06	60.0	COG1729@1|root,COG1729@2|Bacteria,1Q3F0@1224|Proteobacteria,42XMM@68525|delta/epsilon subdivisions,2WTBN@28221|Deltaproteobacteria,2YYTS@29|Myxococcales	28221|Deltaproteobacteria	S	B-box zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1081576_7	1379698.RBG1_1C00001G0684	2.044e-113	389.0	COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104,ko:K18930	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GDHHQS3_k127_1081576_27	1267535.KB906767_gene2921	1.241e-67	242.0	COG0664@1|root,COG0664@2|Bacteria,3Y69P@57723|Acidobacteria	57723|Acidobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_1081576_41	1340493.JNIF01000003_gene4149	9.33e-37	158.0	COG3386@1|root,COG4625@1|root,COG3386@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
GDHHQS3_k127_1081576_25	886293.Sinac_4302	1.326e-75	276.0	COG3266@1|root,COG4655@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,2IZVN@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function (DUF3494)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF3494
GDHHQS3_k127_1081576_64	1123023.JIAI01000007_gene1933	1.643e-13	76.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,2HIHC@201174|Actinobacteria,4DY0Q@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synth
GDHHQS3_k127_1081576_61	742159.HMPREF0004_4367	5.795e-19	92.0	COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,2VWA1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GDHHQS3_k127_1081576_66	523850.TON_0777	1.924e-11	70.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_1126508_23	398767.Glov_2045	3.701e-74	265.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
GDHHQS3_k127_1126508_26	1121920.AUAU01000005_gene1098	7.272e-70	245.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
GDHHQS3_k127_1126508_46	595537.Varpa_0306	5.921e-23	101.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1126508_24	321332.CYB_0917	3.008e-73	274.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
GDHHQS3_k127_1126508_42	593750.Metfor_2328	3.09e-26	114.0	COG0784@1|root,arCOG02589@2157|Archaea,2Y4Q4@28890|Euryarchaeota,2NB3F@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS3_k127_1126508_10	314345.SPV1_02432	4.913e-110	384.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,MASE4,PAS,PAS_3,PAS_9,Response_reg,dCache_1
GDHHQS3_k127_1126508_35	234267.Acid_1844	2.762e-46	173.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_1126508_33	240015.ACP_2356	1.479e-55	200.0	COG0041@1|root,COG0041@2|Bacteria,3Y4MB@57723|Acidobacteria,2JJ9S@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS3_k127_1126508_19	448385.sce7415	6.89e-94	325.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_1126508_14	760192.Halhy_2786	5.386e-105	378.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS3_k127_1126508_7	215803.DB30_0854	3.346e-145	470.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_1126508_45	1121468.AUBR01000002_gene703	1.326e-24	116.0	COG4636@1|root,COG4636@2|Bacteria,1V46Z@1239|Firmicutes,24I1U@186801|Clostridia,42J2X@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GDHHQS3_k127_1126508_38	404589.Anae109_3498	1.668e-41	177.0	COG3386@1|root,COG3386@2|Bacteria,1QYGK@1224|Proteobacteria,437EJ@68525|delta/epsilon subdivisions,2X2KV@28221|Deltaproteobacteria,2Z04K@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1126508_16	575540.Isop_1386	1.023e-101	337.0	COG0388@1|root,COG0388@2|Bacteria,2IZEX@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
GDHHQS3_k127_1126508_5	1128421.JAGA01000001_gene2449	2.583e-173	561.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
GDHHQS3_k127_1126508_6	323097.Nham_3560	5.329e-149	486.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria,3JRVZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
GDHHQS3_k127_1126508_15	1031711.RSPO_c02010	3.291e-104	346.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,1K0GI@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter, inner membrane subunit CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
GDHHQS3_k127_1126508_18	1266925.JHVX01000003_gene615	8.07e-101	361.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,3729U@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
GDHHQS3_k127_1126508_13	1128421.JAGA01000001_gene2453	2.163e-106	378.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2NS4W@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	vncS	-	2.7.13.3	ko:K07641,ko:K10819	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_1126508_28	1128421.JAGA01000001_gene2454	3.25e-61	238.0	COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria	2|Bacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1126508_8	1127673.GLIP_3752	4.207e-124	417.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,465VV@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
GDHHQS3_k127_1126508_47	1268622.AVS7_01871	2.221e-17	87.0	COG0640@1|root,COG0640@2|Bacteria,1PT7V@1224|Proteobacteria,2VSXK@28216|Betaproteobacteria,4AENG@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GDHHQS3_k127_1126508_50	1125863.JAFN01000001_gene2973	9.052e-15	87.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GDHHQS3_k127_1126508_1	269799.Gmet_3127	1.132e-314	1015.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,43TI4@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
GDHHQS3_k127_1126508_41	1121439.dsat_0795	9.225e-30	138.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2M8H5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_1126508_49	1123517.JOMR01000001_gene1560	9.069e-16	90.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1RYS4@1236|Gammaproteobacteria,461IB@72273|Thiotrichales	72273|Thiotrichales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_1126508_4	1210884.HG799465_gene12156	1.737e-216	709.0	COG1643@1|root,COG1643@2|Bacteria,2IX3C@203682|Planctomycetes	203682|Planctomycetes	L	ATP-dependent helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
GDHHQS3_k127_1126508_9	1185876.BN8_00008	3.718e-121	437.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_1126508_30	1121935.AQXX01000111_gene5788	1.572e-57	218.0	COG1073@1|root,COG1073@2|Bacteria,1RCY0@1224|Proteobacteria,1SZ5J@1236|Gammaproteobacteria,1XQRF@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS3_k127_1126508_2	1382359.JIAL01000001_gene577	5.403e-261	822.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_1126508_25	204669.Acid345_1052	1.818e-70	263.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_1126508_51	1463900.JOIX01000001_gene6231	1.403e-05	58.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
GDHHQS3_k127_1126508_3	1121015.N789_01925	9.24e-258	807.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1X4DN@135614|Xanthomonadales	135614|Xanthomonadales	E	converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_1126508_27	292415.Tbd_0168	1.281e-64	230.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,1KT0S@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Calcineurin-like phosphoesterase	-	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
GDHHQS3_k127_1126508_17	1123242.JH636435_gene862	6.442e-101	355.0	COG1680@1|root,COG1680@2|Bacteria,2IZG3@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_1126508_21	1232410.KI421426_gene1424	8.936e-80	284.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43RXY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
GDHHQS3_k127_1126508_32	1313172.YM304_07470	2.131e-56	205.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS3_k127_1126508_0	324602.Caur_1881	0.0	1045.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_1126508_11	28444.JODQ01000003_gene4777	6.855e-109	382.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EH4D@85012|Streptosporangiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
GDHHQS3_k127_1126508_44	1382356.JQMP01000003_gene1853	4.004e-25	108.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GDHHQS3_k127_1126508_39	1267535.KB906767_gene4593	1.636e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GDHHQS3_k127_1126508_12	289376.THEYE_A0433	9.792e-107	366.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
GDHHQS3_k127_1126508_40	1120973.AQXL01000135_gene1478	3.743e-30	137.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,278EE@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_1126508_29	1408418.JNJH01000012_gene3556	1.578e-60	226.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_1126508_37	1121920.AUAU01000026_gene1478	1.344e-41	164.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_1126508_34	378806.STAUR_0109	5.156e-47	171.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2Z1RY@29|Myxococcales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_1126508_31	502025.Hoch_5093	4.609e-57	217.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS3_k127_1126508_36	321332.CYB_1404	1.096e-41	157.0	COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria,1H3ZE@1129|Synechococcus	1117|Cyanobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS3_k127_1126508_22	1122221.JHVI01000003_gene383	5.524e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,1WIJY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1126508_43	999611.KI421504_gene3131	3.296e-26	122.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,281HF@191028|Leisingera	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_1126508_20	448385.sce1998	6.031e-91	314.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GDHHQS3_k127_1138901_3	1121957.ATVL01000010_gene512	1.6e-15	88.0	28N37@1|root,2ZB8Y@2|Bacteria,4NK7W@976|Bacteroidetes,47KK0@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
GDHHQS3_k127_1138901_2	880072.Desac_1962	4.467e-47	196.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CF9@68525|delta/epsilon subdivisions,2X7QB@28221|Deltaproteobacteria,2MS55@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16087,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.2,1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_1138901_0	1211115.ALIQ01000164_gene3402	1.008e-103	342.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,3N9NR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	ABC transporter	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_1169956_17	414684.RC1_3308	2.453e-18	87.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2JS5A@204441|Rhodospirillales	204441|Rhodospirillales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
GDHHQS3_k127_1169956_9	68570.DC74_1100	5.737e-111	379.0	COG0169@1|root,COG0169@2|Bacteria	2|Bacteria	E	shikimate 3-dehydrogenase (NADP+) activity	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25,4.2.1.10	ko:K00014,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
GDHHQS3_k127_1169956_8	1266914.ATUK01000014_gene2111	5.497e-116	393.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WX6V@135613|Chromatiales	135613|Chromatiales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS3_k127_1169956_12	1234364.AMSF01000060_gene969	8.659e-62	220.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS3_k127_1169956_10	867903.ThesuDRAFT_01414	2.575e-89	319.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WCZN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS3_k127_1169956_13	1122185.N792_01460	1.771e-41	174.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1X42P@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS3_k127_1169956_14	502025.Hoch_3583	5.185e-39	159.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,2YXEI@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS3_k127_1169956_4	204669.Acid345_1158	2.103e-163	526.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria,2JIVM@204432|Acidobacteriia	204432|Acidobacteriia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1169956_11	269799.Gmet_2477	1.059e-67	245.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS3_k127_1169956_6	861299.J421_4293	4.617e-157	517.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	2|Bacteria	S	ABC1 family	ubiB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	iYL1228.KPN_04331	ABC1
GDHHQS3_k127_1169956_1	1313421.JHBV01000032_gene1648	3.558e-207	656.0	COG1257@1|root,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,1IRAQ@117747|Sphingobacteriia	976|Bacteroidetes	I	Hydroxymethylglutaryl-coenzyme A reductase	hmgA	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
GDHHQS3_k127_1169956_2	401526.TcarDRAFT_2500	4.482e-181	586.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H43N@909932|Negativicutes	909932|Negativicutes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_1169956_7	926561.KB900621_gene2771	1.193e-137	463.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WAAB@53433|Halanaerobiales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS3_k127_1169956_5	204669.Acid345_1455	6.907e-162	541.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_1169956_0	861299.J421_4119	2.069e-214	675.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS3_k127_1169956_3	1449347.JQLN01000005_gene4498	2.051e-168	561.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,2M23C@2063|Kitasatospora	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_1169956_15	1242864.D187_009939	6.058e-37	149.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
GDHHQS3_k127_1169956_16	234267.Acid_4496	1.574e-28	122.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_1196097_3	234267.Acid_7393	7.376e-96	336.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_1196097_1	1565129.JSFF01000008_gene2675	2.772e-175	586.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,2Q9QW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS3_k127_1196097_7	234267.Acid_5312	2.08e-16	94.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS3_k127_1196097_4	1121920.AUAU01000007_gene444	2.27e-69	237.0	COG0432@1|root,COG0432@2|Bacteria,3Y4R6@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_1196097_2	1047013.AQSP01000123_gene1523	4.018e-101	366.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_1196097_5	861299.J421_2096	1.884e-63	234.0	COG3279@1|root,COG3279@2|Bacteria,1ZTKG@142182|Gemmatimonadetes	2|Bacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,LytTR,Response_reg
GDHHQS3_k127_1196097_6	1278073.MYSTI_05666	2.328e-51	198.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
GDHHQS3_k127_1196097_8	1367847.JCM7686_pAMI4p297	1.187e-05	59.0	COG1309@1|root,COG1309@2|Bacteria,1QA4Q@1224|Proteobacteria,2V7X5@28211|Alphaproteobacteria,2PYTE@265|Paracoccus	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GDHHQS3_k127_1196097_0	1121920.AUAU01000001_gene2279	0.0	1107.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_1196707_3	309801.trd_A0561	4.143e-23	111.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_1196707_4	1449357.JQLK01000003_gene2530	1.205e-15	85.0	2EH09@1|root,33ASB@2|Bacteria,1WKPC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_1196707_2	596152.DesU5LDRAFT_0222	4.184e-25	106.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,42VC8@68525|delta/epsilon subdivisions,2WS7K@28221|Deltaproteobacteria,2ME70@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_1196707_0	1379270.AUXF01000001_gene2842	8.85e-53	201.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GDHHQS3_k127_1196707_1	1120705.FG95_02795	6.594e-33	131.0	2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UE6T@28211|Alphaproteobacteria,2KCI3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1201371_8	46429.BV95_00589	4.063e-38	145.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,2K1W2@204457|Sphingomonadales	204457|Sphingomonadales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS3_k127_1201371_3	1331060.RLDS_24295	8.105e-98	340.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,2K06B@204457|Sphingomonadales	204457|Sphingomonadales	P	chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS3_k127_1201371_2	1385517.N800_09760	8.866e-101	357.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_1201371_9	929712.KI912613_gene3526	0.0003797	52.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GDHHQS3_k127_1201371_6	1142394.PSMK_19700	3.449e-62	225.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_1201371_7	1206733.BAGC01000043_gene793	2.293e-57	219.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4FZ0W@85025|Nocardiaceae	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_1201371_5	1173028.ANKO01000030_gene3279	6.005e-63	228.0	COG1216@1|root,COG1216@2|Bacteria,1G2MT@1117|Cyanobacteria,1H8YG@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
GDHHQS3_k127_1201371_1	1122611.KB903977_gene2804	2.539e-121	404.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria,4EI2K@85012|Streptosporangiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
GDHHQS3_k127_1201371_0	883080.HMPREF9697_02183	5.786e-217	690.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,3JRTE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	fdsB	-	1.12.1.2,1.6.5.3	ko:K00124,ko:K00335,ko:K18005	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_1201371_4	446468.Ndas_4111	7.894e-94	312.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
GDHHQS3_k127_1231504_9	945713.IALB_1902	1.231e-93	310.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS3_k127_1231504_2	671143.DAMO_1102	2.637e-184	602.0	COG4590@1|root,COG4590@2|Bacteria,2NS4H@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_1231504_4	671143.DAMO_1101	7.016e-169	578.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_1231504_7	1123020.AUIE01000002_gene1506	1.036e-115	379.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1YETA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_1231504_3	861299.J421_0838	1.298e-178	589.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1ZV6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GDHHQS3_k127_1231504_19	404589.Anae109_1481	1.019e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS3_k127_1231504_20	1265505.ATUG01000001_gene3942	0.0005558	53.0	COG0664@1|root,COG1033@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
GDHHQS3_k127_1231504_17	215803.DB30_7168	8.867e-22	111.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS3_k127_1231504_0	204669.Acid345_2979	5.802e-270	848.0	COG1680@1|root,COG1680@2|Bacteria,3Y3T0@57723|Acidobacteria,2JHSK@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_1231504_18	861299.J421_0958	2.458e-10	66.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_1231504_6	861299.J421_0566	1.997e-127	444.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0566|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1231504_1	234267.Acid_3743	8.039e-261	822.0	COG3590@1|root,COG3590@2|Bacteria,3Y3CC@57723|Acidobacteria	57723|Acidobacteria	O	Endothelin-converting enzyme	-	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
GDHHQS3_k127_1231504_10	296591.Bpro_2639	8.42e-84	287.0	COG1917@1|root,COG1917@2|Bacteria,1RH0Y@1224|Proteobacteria,2VWWA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1231504_5	861299.J421_0330	4.135e-135	447.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS3_k127_1231504_13	1163409.UUA_10866	1.613e-57	211.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1S5JW@1236|Gammaproteobacteria,1XC1Y@135614|Xanthomonadales	135614|Xanthomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
GDHHQS3_k127_1231504_8	414684.RC1_2426	9.73e-98	341.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2JPJ7@204441|Rhodospirillales	204441|Rhodospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GDHHQS3_k127_1231504_14	190486.XAC3368	1.753e-45	184.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS3_k127_1231504_11	1442599.JAAN01000011_gene396	3.896e-82	286.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1MVI4@1224|Proteobacteria,1S1IH@1236|Gammaproteobacteria,1X71U@135614|Xanthomonadales	135614|Xanthomonadales	M	peptidoglycan-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
GDHHQS3_k127_1231504_15	441620.Mpop_2928	2.678e-30	122.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,1JVP5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS3_k127_1231504_16	1201290.M902_2354	6.114e-23	102.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42WQS@68525|delta/epsilon subdivisions,2MUEY@213481|Bdellovibrionales,2WRPT@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS3_k127_1231504_12	866536.Belba_0340	5.819e-70	246.0	COG0639@1|root,COG0639@2|Bacteria,4NIDG@976|Bacteroidetes,47MI8@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
GDHHQS3_k127_1372421_38	1286631.X805_12940	4.568e-08	64.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1KITS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
GDHHQS3_k127_1372421_28	502025.Hoch_5724	8.939e-38	154.0	COG1610@1|root,COG1610@2|Bacteria,1PS1I@1224|Proteobacteria,43A7B@68525|delta/epsilon subdivisions,2X2EM@28221|Deltaproteobacteria,2Z2BW@29|Myxococcales	28221|Deltaproteobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS3_k127_1372421_17	266265.Bxe_B1891	5.637e-67	247.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2VQEW@28216|Betaproteobacteria,1K877@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
GDHHQS3_k127_1372421_11	269799.Gmet_2726	6.195e-107	354.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS3_k127_1372421_0	404380.Gbem_1577	0.0	1228.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GDHHQS3_k127_1372421_31	1121403.AUCV01000040_gene4283	1.285e-28	129.0	2FKDJ@1|root,34C0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1372421_21	316274.Haur_0962	1.175e-43	164.0	COG1764@1|root,COG1764@2|Bacteria,2G6W8@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_1372421_26	1211114.ALIP01000052_gene28	2.561e-38	154.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GDHHQS3_k127_1372421_15	869210.Marky_1109	3.617e-78	279.0	COG0053@1|root,COG0053@2|Bacteria,1WI3N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czrB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS3_k127_1372421_3	204669.Acid345_3122	3.262e-142	494.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GDHHQS3_k127_1372421_7	1089550.ATTH01000001_gene1255	1.687e-110	379.0	COG0728@1|root,COG0728@2|Bacteria,4PF1K@976|Bacteroidetes,1FK01@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_1372421_33	247634.GPB2148_2519	9.977e-28	132.0	COG0457@1|root,COG0457@2|Bacteria,1R9C8@1224|Proteobacteria,1RY5F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8,Transglut_core
GDHHQS3_k127_1372421_13	518766.Rmar_1440	4.657e-84	291.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
GDHHQS3_k127_1372421_9	518766.Rmar_1441	1.106e-109	370.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1372421_12	518766.Rmar_1442	5.411e-102	347.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1FIY8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1372421_14	1449126.JQKL01000031_gene1124	3.602e-80	278.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,268T7@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1372421_16	234267.Acid_0826	1.566e-75	270.0	COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria	57723|Acidobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
GDHHQS3_k127_1372421_32	1379698.RBG1_1C00001G0109	5.413e-28	132.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
GDHHQS3_k127_1372421_8	247490.KSU1_D0782	1.753e-110	384.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1372421_43	383372.Rcas_2727	7.124e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,2GBMH@200795|Chloroflexi,3782E@32061|Chloroflexia	32061|Chloroflexia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_1372421_39	768704.Desmer_4319	3.041e-06	60.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_1372421_45	502025.Hoch_4722	0.0003287	53.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria,2YVFJ@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
GDHHQS3_k127_1372421_10	1379698.RBG1_1C00001G1660	1.245e-109	366.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GDHHQS3_k127_1372421_4	204669.Acid345_0206	5.204e-129	441.0	COG2989@1|root,COG2989@2|Bacteria,3Y2YW@57723|Acidobacteria,2JIFK@204432|Acidobacteriia	2|Bacteria	S	ErfK YbiS YcfS YnhG family protein	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GDHHQS3_k127_1372421_2	518766.Rmar_2682	7.496e-160	522.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1FIU1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
GDHHQS3_k127_1372421_6	518766.Rmar_0181	6.16e-118	388.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1FIUF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_1372421_24	379066.GAU_3352	6.31e-40	156.0	COG1528@1|root,COG1528@2|Bacteria,1ZUFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rubrerythrin	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GDHHQS3_k127_1372421_41	1340493.JNIF01000003_gene2301	1.727e-05	58.0	COG0136@1|root,COG0136@2|Bacteria,3Y395@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_1372421_19	1380358.JADJ01000022_gene3775	2.375e-47	188.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XIQ5@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_1372421_27	405948.SACE_0521	7.324e-38	154.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4DZG8@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GDHHQS3_k127_1372421_42	289376.THEYE_A0863	4.621e-05	50.0	2DRP0@1|root,33CFM@2|Bacteria,3J1BN@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
GDHHQS3_k127_1372421_35	1122613.ATUP01000001_gene1349	5.699e-16	86.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,43YIG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_1372421_36	1509405.GV67_11850	7.641e-14	80.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,4BASV@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_1372421_1	269799.Gmet_1424	5.616e-218	705.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS3_k127_1372421_22	1042876.PPS_1710	4.351e-43	183.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1YWM9@136845|Pseudomonas putida group	1236|Gammaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790	Glyco_hydro_3
GDHHQS3_k127_1372421_23	443143.GM18_4442	2.488e-42	159.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,43SIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS3_k127_1372421_25	1125863.JAFN01000001_gene2072	1.14e-39	160.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS3_k127_1372421_18	671143.DAMO_2078	1.097e-52	207.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS3_k127_1372421_37	622637.KE124774_gene3792	5.743e-12	69.0	COG0776@1|root,COG0776@2|Bacteria,1RHMP@1224|Proteobacteria,2U9KS@28211|Alphaproteobacteria,370EB@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Bacterial DNA-binding protein	-	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS3_k127_1372421_30	443143.GM18_0157	2.614e-30	137.0	COG1413@1|root,COG2804@1|root,COG1413@2|Bacteria,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	2.4.1.227,2.7.11.1,3.4.11.2	ko:K01256,ko:K02563,ko:K02652,ko:K08776,ko:K12132	ko00480,ko00550,ko01100,ko01502,ko04112,map00480,map00550,map01100,map01502,map04112	-	R00899,R04951,R05032,R05662	RC00005,RC00049,RC00096,RC00141	ko00000,ko00001,ko01000,ko01001,ko01002,ko01011,ko02035,ko02044	3.A.15.2	GT28	-	HEAT_2,Sulfatase,T2SSE_N
GDHHQS3_k127_1372421_29	483219.LILAB_31135	1.077e-31	143.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
GDHHQS3_k127_1372421_20	880072.Desac_1280	3.671e-46	179.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_1372421_34	404589.Anae109_0126	2.37e-25	113.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
GDHHQS3_k127_1372421_5	234267.Acid_7096	7.885e-124	406.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS3_k127_1372421_40	1267535.KB906767_gene747	7.411e-06	49.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS3_k127_1388917_1	1121123.AUAO01000001_gene966	4.111e-16	79.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS3_k127_1388917_0	1161401.ASJA01000001_gene239	6.439e-80	278.0	COG1235@1|root,COG1235@2|Bacteria,1PVWC@1224|Proteobacteria,2V746@28211|Alphaproteobacteria,43Z2A@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
GDHHQS3_k127_1450859_7	1121448.DGI_1586	2.778e-24	106.0	COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2
GDHHQS3_k127_1450859_5	1206733.BAGC01000044_gene848	1.268e-42	159.0	2EHMA@1|root,33BD2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_1450859_1	452637.Oter_3749	2.199e-78	273.0	COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae	414999|Opitutae	U	Pfam:Arch_ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
GDHHQS3_k127_1450859_4	926569.ANT_10890	7.735e-53	194.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_1450859_6	330084.JNYZ01000011_gene7271	1.442e-42	181.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria,4DYR9@85010|Pseudonocardiales	201174|Actinobacteria	P	Alkaline phosphatase	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
GDHHQS3_k127_1450859_2	100226.SCO0575	4.13e-71	264.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS3_k127_1450859_0	1184267.A11Q_1045	4.74e-107	366.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42RH4@68525|delta/epsilon subdivisions,2MTJP@213481|Bdellovibrionales,2WNQ0@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_1450859_3	1121448.DGI_0738	6.282e-64	233.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2M9CM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1450859_8	1536772.R70723_28640	0.0003476	48.0	COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,26SEA@186822|Paenibacillaceae	91061|Bacilli	C	virulence factor	ypgR	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
GDHHQS3_k127_1453733_2	748658.KB907313_gene2347	8.033e-47	181.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_1453733_1	243231.GSU1005	1.956e-72	256.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,43U4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
GDHHQS3_k127_1453733_4	555088.DealDRAFT_1413	1.035e-39	168.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,24DMW@186801|Clostridia	186801|Clostridia	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
GDHHQS3_k127_1453733_3	880073.Calab_0107	1.323e-44	177.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_1453733_0	682795.AciX8_1432	3.357e-115	395.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_1453733_5	665571.STHERM_c18480	2.605e-24	119.0	COG1739@1|root,COG1739@2|Bacteria,2J7AS@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1949,UPF0029
GDHHQS3_k127_1542868_4	1304872.JAGC01000003_gene3083	1.483e-76	264.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1542868_12	644282.Deba_0647	7.778e-26	111.0	2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1542868_9	682795.AciX8_0031	1.688e-44	183.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria,2JJH8@204432|Acidobacteriia	204432|Acidobacteriia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS3_k127_1542868_14	1340493.JNIF01000003_gene4084	7.566e-23	116.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS3_k127_1542868_17	1047013.AQSP01000088_gene1634	0.0004812	54.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
GDHHQS3_k127_1542868_10	1198114.AciX9_1304	5.611e-31	142.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS3_k127_1542868_16	1047013.AQSP01000131_gene1842	1.353e-15	92.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
GDHHQS3_k127_1542868_3	309801.trd_1634	1.768e-83	291.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,27XYX@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_1542868_6	351607.Acel_0689	1.146e-75	281.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4ERNJ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS3_k127_1542868_11	1307759.JOMJ01000003_gene1767	1.22e-26	115.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,431FU@68525|delta/epsilon subdivisions,2WWSN@28221|Deltaproteobacteria,2MH64@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
GDHHQS3_k127_1542868_15	1255043.TVNIR_2866	2.078e-22	111.0	28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria,1S7TF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1542868_7	396588.Tgr7_0758	2.538e-66	233.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1WWCD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS3_k127_1542868_0	639030.JHVA01000001_gene1853	2.376e-207	648.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GDHHQS3_k127_1542868_13	926550.CLDAP_33420	5.194e-25	117.0	COG1977@1|root,COG1977@2|Bacteria,2G6VH@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1542868_1	1173026.Glo7428_1703	1.597e-108	370.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GDHHQS3_k127_1542868_2	1267535.KB906767_gene3318	1.495e-102	346.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS3_k127_1542868_5	243231.GSU0652	9.501e-76	267.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,43VVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GDHHQS3_k127_1542868_8	671143.DAMO_2425	1.338e-56	206.0	COG0388@1|root,COG0388@2|Bacteria,2NQD8@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GDHHQS3_k127_154736_6	211114.JOEF01000007_gene865	1.82e-22	106.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GDHHQS3_k127_154736_5	1379270.AUXF01000004_gene2945	1.502e-32	134.0	2E3B5@1|root,32YAP@2|Bacteria,1ZUWQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
GDHHQS3_k127_154736_0	452637.Oter_0021	2.86e-222	717.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_154736_3	234267.Acid_5465	1.514e-74	287.0	COG0577@1|root,COG0577@2|Bacteria,3Y6MX@57723|Acidobacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_154736_1	330214.NIDE0014	8.58e-144	466.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_154736_2	1183438.GKIL_2917	4.573e-106	360.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_154736_4	234267.Acid_3938	4.59e-55	199.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_1552400_13	880072.Desac_2520	2.826e-44	174.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
GDHHQS3_k127_1552400_19	485917.Phep_1484	1.9e-24	121.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
GDHHQS3_k127_1552400_25	266265.Bxe_A0959	0.0008696	50.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria,1K1TE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
GDHHQS3_k127_1552400_18	1131812.JQMS01000001_gene1039	1.376e-29	137.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia,2NSTM@237|Flavobacterium	976|Bacteroidetes	S	BatB protein	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS3_k127_1552400_8	1499967.BAYZ01000019_gene6265	1.342e-67	254.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
GDHHQS3_k127_1552400_9	1499967.BAYZ01000069_gene1845	4.505e-67	255.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_1552400_4	1499967.BAYZ01000069_gene1846	7.545e-114	390.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_1552400_17	563192.HMPREF0179_00717	1.376e-35	150.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2MB4Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS3_k127_1552400_22	357808.RoseRS_1781	1.211e-06	60.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
GDHHQS3_k127_1552400_3	204669.Acid345_1052	3.317e-129	447.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_1552400_23	498848.TaqDRAFT_5022	9.878e-06	53.0	2DSSK@1|root,33H9W@2|Bacteria,1WKNZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_1552400_21	419947.MRA_1850	4.149e-20	92.0	2BE1Z@1|root,327SM@2|Bacteria,2HDGJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1552400_12	419947.MRA_1849	9.177e-45	169.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_1552400_0	1382359.JIAL01000001_gene136	6.198e-162	538.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS3_k127_1552400_7	89187.ISM_13735	2.798e-73	257.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,46P7S@74030|Roseovarius	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS3_k127_1552400_11	349124.Hhal_2321	1.663e-52	211.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
GDHHQS3_k127_1552400_20	1123253.AUBD01000007_gene586	2.608e-24	104.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS3_k127_1552400_14	522306.CAP2UW1_2822	3.192e-43	171.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_1552400_15	644282.Deba_0457	4.944e-41	158.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS3_k127_1552400_5	502025.Hoch_3717	2.117e-88	312.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
GDHHQS3_k127_1552400_10	926550.CLDAP_34690	1.028e-65	253.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_1552400_2	1112212.JH584235_gene1822	6.243e-132	443.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS3_k127_1552400_16	330214.NIDE2034	1.013e-39	155.0	COG0797@1|root,COG0797@2|Bacteria,3J0PD@40117|Nitrospirae	40117|Nitrospirae	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
GDHHQS3_k127_1552400_1	1304880.JAGB01000001_gene254	1.261e-142	467.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GDHHQS3_k127_1552400_6	582515.KR51_00029290	8.179e-78	286.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1FY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
GDHHQS3_k127_1552400_24	5059.CADAFLAP00012376	2.112e-05	57.0	COG0127@1|root,KOG3222@2759|Eukaryota,38DZ3@33154|Opisthokonta,3P1W0@4751|Fungi,3QNUD@4890|Ascomycota,20GRY@147545|Eurotiomycetes,3S39C@5042|Eurotiales	4751|Fungi	F	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions	HAM1	GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008828,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036217,GO:0036218,GO:0036219,GO:0036220,GO:0036221,GO:0036222,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0047840,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	ko:K01519	ko00230,ko00983,ko01100,map00230,map00983,map01100	-	R00426,R00720,R01855,R02100,R02720,R03531,R08243	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS3_k127_1592859_1	1380354.JIAN01000009_gene3676	2.74e-11	76.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Pkinase
GDHHQS3_k127_1592859_0	566466.NOR53_3522	1.18e-56	218.0	COG0457@1|root,COG0457@2|Bacteria,1MYQU@1224|Proteobacteria,1RWMR@1236|Gammaproteobacteria,1JABK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
GDHHQS3_k127_1594474_1	661478.OP10G_0723	1.354e-97	327.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1594474_3	1411123.JQNH01000001_gene3017	2.7e-79	272.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_1594474_4	234267.Acid_4707	8.816e-70	249.0	COG0697@1|root,COG0697@2|Bacteria,3Y570@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_1594474_0	383372.Rcas_3594	4.164e-188	616.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_1594474_2	656519.Halsa_1185	7.43e-90	306.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,3WBH8@53433|Halanaerobiales	186801|Clostridia	S	PFAM C4-dicarboxylate anaerobic carrier-like	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
GDHHQS3_k127_1645835_1	1380394.JADL01000024_gene101	7.349e-227	723.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
GDHHQS3_k127_1645835_21	403833.Pmob_1344	2.713e-06	62.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
GDHHQS3_k127_1645835_0	215803.DB30_4063	1.122e-235	744.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS3_k127_1645835_6	595537.Varpa_3262	6.579e-106	365.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
GDHHQS3_k127_1645835_8	1469607.KK073768_gene1058	8.595e-100	357.0	COG4242@1|root,COG4242@2|Bacteria,1G4I0@1117|Cyanobacteria,1HMS8@1161|Nostocales	1117|Cyanobacteria	PQ	Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS3_k127_1645835_19	1196323.ALKF01000137_gene3393	1.092e-19	94.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,26Z1F@186822|Paenibacillaceae	91061|Bacilli	K	GntR family transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GDHHQS3_k127_1645835_12	1123389.ATXJ01000001_gene757	2.582e-39	158.0	COG1131@1|root,COG1131@2|Bacteria,1WI6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1645835_4	1254432.SCE1572_12175	8.015e-198	627.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria,2YXDW@29|Myxococcales	28221|Deltaproteobacteria	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
GDHHQS3_k127_1645835_9	1144275.COCOR_07801	1.482e-92	317.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42WVB@68525|delta/epsilon subdivisions,2WT41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1645835_11	1239962.C943_03089	1.769e-51	209.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,47N78@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_8
GDHHQS3_k127_1645835_3	565045.NOR51B_1262	3.469e-198	653.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1J5WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_1645835_7	604331.AUHY01000006_gene832	2.014e-104	352.0	COG1960@1|root,COG1960@2|Bacteria,1WITX@1297|Deinococcus-Thermus	2|Bacteria	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_1645835_13	477974.Daud_0538	7.862e-38	160.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DC@186807|Peptococcaceae	186801|Clostridia	T	Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,PAS,PocR,SBP_bac_3
GDHHQS3_k127_1645835_14	379066.GAU_3641	1.203e-37	153.0	2CHCP@1|root,32S5R@2|Bacteria,1ZV1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_1645835_10	1121924.ATWH01000022_gene3191	2.724e-91	319.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FRXV@85023|Microbacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_1645835_5	439235.Dalk_1929	4.815e-129	447.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MJ3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GDHHQS3_k127_1645835_15	926560.KE387026_gene4250	1.14e-36	145.0	2DEWP@1|root,2ZPJE@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_1645835_20	395965.Msil_3485	1.403e-18	89.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1645835_16	395965.Msil_3484	6.56e-32	132.0	COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_1645835_17	452637.Oter_1909	1.446e-29	133.0	COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_1645835_2	1267535.KB906767_gene2453	3.297e-226	715.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,Trypsin_2
GDHHQS3_k127_1768106_0	234267.Acid_2214	3.999e-118	407.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1775754_15	378806.STAUR_1719	0.0001212	55.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2YTYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_1775754_7	886293.Sinac_1308	4.706e-51	200.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_1775754_3	398767.Glov_1587	6.202e-64	246.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
GDHHQS3_k127_1775754_8	472759.Nhal_2909	6.586e-50	189.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,1S5S8@1236|Gammaproteobacteria,1WYBG@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_1775754_14	1094561.MEI_00912	0.0001156	51.0	COG4575@1|root,COG4575@2|Bacteria,1NGZU@1224|Proteobacteria,2UJGB@28211|Alphaproteobacteria,48U7S@772|Bartonellaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
GDHHQS3_k127_1775754_0	290397.Adeh_1776	1.916e-133	442.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GDHHQS3_k127_1775754_11	290398.Csal_1895	3.688e-16	92.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XIWX@135619|Oceanospirillales	135619|Oceanospirillales	K	membrane	rbn-1	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS3_k127_1775754_13	85643.Tmz1t_1090	2.338e-07	61.0	2AII3@1|root,31901@2|Bacteria,1Q1AT@1224|Proteobacteria,2W6DW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1775754_4	1461694.ATO9_01450	1.702e-60	216.0	COG3631@1|root,COG3631@2|Bacteria,1RGEA@1224|Proteobacteria,2U7YB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GDHHQS3_k127_1775754_6	1121116.KB894766_gene417	1.744e-54	196.0	arCOG14922@1|root,32SW8@2|Bacteria,1N0NY@1224|Proteobacteria,2VV7B@28216|Betaproteobacteria,4AF7R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GDHHQS3_k127_1775754_1	196162.Noca_1788	4.49e-108	385.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4DTHI@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
GDHHQS3_k127_1775754_10	379066.GAU_3341	6.21e-33	135.0	2ECKJ@1|root,33KDJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_1775754_9	269799.Gmet_2623	1.962e-42	164.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,43SYV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
GDHHQS3_k127_1775754_5	1247963.JPHU01000012_gene933	1.989e-56	211.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_1775754_2	204669.Acid345_4392	2.145e-90	320.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_1785708_9	1231190.NA8A_17378	1.903e-06	55.0	COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,2TVH9@28211|Alphaproteobacteria,43KQ0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	ChrR Cupin-like domain	chrR	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7,zf-HC2
GDHHQS3_k127_1785708_8	452652.KSE_19280	6.092e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,2M15V@2063|Kitasatospora	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_1785708_5	1384056.N787_10795	1.133e-57	224.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,1S95H@1236|Gammaproteobacteria,1X5RN@135614|Xanthomonadales	135614|Xanthomonadales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1785708_4	329726.AM1_2962	5.297e-70	254.0	COG0605@1|root,COG0605@2|Bacteria,1G0VH@1117|Cyanobacteria	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS3_k127_1785708_0	335543.Sfum_0872	1.125e-184	591.0	COG1847@1|root,COG3854@1|root,COG1847@2|Bacteria,COG3854@2|Bacteria,1MWTB@1224|Proteobacteria,42P75@68525|delta/epsilon subdivisions,2WJX3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
GDHHQS3_k127_1785708_7	1385935.N836_05455	5.333e-45	190.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,Y_Y_Y
GDHHQS3_k127_1785708_6	1183438.GKIL_1934	1.128e-48	191.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS3_k127_1785708_1	748280.NH8B_2178	9.785e-126	415.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,2KRXC@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_1785708_3	671143.DAMO_2381	3.362e-96	333.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
GDHHQS3_k127_1785708_2	472759.Nhal_0689	9.185e-117	382.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS3_k127_2002669_13	521011.Mpal_0100	4.009e-14	82.0	COG3291@1|root,arCOG02420@1|root,arCOG02420@2157|Archaea,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N,SdrD_B
GDHHQS3_k127_2002669_15	290397.Adeh_3810	1.689e-08	67.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2002669_14	765420.OSCT_0828	1.654e-08	61.0	COG2018@1|root,COG2018@2|Bacteria,2GB8V@200795|Chloroflexi,377K6@32061|Chloroflexia	32061|Chloroflexia	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GDHHQS3_k127_2002669_7	204669.Acid345_3288	1.647e-34	138.0	COG0511@1|root,COG0511@2|Bacteria,3Y4W8@57723|Acidobacteria,2JJHQ@204432|Acidobacteriia	204432|Acidobacteriia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GDHHQS3_k127_2002669_1	1242864.D187_006590	6.115e-181	577.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS3_k127_2002669_10	639030.JHVA01000001_gene80	1.873e-29	136.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria,2JJM3@204432|Acidobacteriia	204432|Acidobacteriia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_2002669_11	634177.GLX_25530	8.108e-24	115.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GDHHQS3_k127_2002669_3	1047013.AQSP01000033_gene1389	3.972e-64	237.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS3_k127_2002669_9	452637.Oter_1802	7.421e-30	126.0	COG3241@1|root,COG3241@2|Bacteria,46W0N@74201|Verrucomicrobia,3K84F@414999|Opitutae	414999|Opitutae	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
GDHHQS3_k127_2002669_0	903818.KI912268_gene3150	2.09e-219	696.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_2002669_8	240015.ACP_1606	4.179e-34	149.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria,2JIYJ@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS3_k127_2002669_6	483219.LILAB_31475	2.044e-39	166.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GDHHQS3_k127_2002669_2	401526.TcarDRAFT_1319	9.292e-67	240.0	COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H1UR@909932|Negativicutes	909932|Negativicutes	M	Bifunctional protein	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
GDHHQS3_k127_2002669_4	1184609.KILIM_146_00020	2.917e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4F6PW@85018|Dermatophilaceae	201174|Actinobacteria	K	Sigma-70 region 2	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2002669_17	526226.Gbro_3524	0.000449	46.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4GEVY@85026|Gordoniaceae	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_2002669_16	1121403.AUCV01000028_gene2440	1.737e-06	56.0	COG0526@1|root,COG0526@2|Bacteria,1RHR7@1224|Proteobacteria,42WV1@68525|delta/epsilon subdivisions,2WSIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_2002669_12	1380387.JADM01000001_gene44	5.066e-16	87.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XHD2@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
GDHHQS3_k127_2032872_0	1121920.AUAU01000010_gene72	1.913e-312	978.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_2036008_8	1280941.HY2_12935	2.221e-11	67.0	COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,2TVH9@28211|Alphaproteobacteria,43XVA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Anti-sigma factor	chrR	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7,zf-HC2
GDHHQS3_k127_2036008_5	1392502.JNIO01000008_gene1630	1.699e-50	190.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9D1@909932|Negativicutes	909932|Negativicutes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
GDHHQS3_k127_2036008_3	1121920.AUAU01000002_gene2003	4.112e-75	264.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GDHHQS3_k127_2036008_0	1121918.ARWE01000001_gene825	4.124e-134	441.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,43SXY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
GDHHQS3_k127_2036008_6	316067.Geob_2150	2.83e-47	179.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,43TAA@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS3_k127_2036008_7	903818.KI912268_gene1547	1.876e-21	106.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
GDHHQS3_k127_2036008_4	649638.Trad_1462	2.48e-69	261.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_2036008_1	234267.Acid_5661	4.367e-109	359.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_2036008_2	1121920.AUAU01000013_gene1763	5.381e-86	306.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000013_gene1763|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2039251_8	272558.10173634	7.572e-21	99.0	COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4HGDN@91061|Bacilli,1ZBT2@1386|Bacillus	91061|Bacilli	S	B3/4 domain	yhzB	-	-	-	-	-	-	-	-	-	-	-	B3_4
GDHHQS3_k127_2039251_7	879212.DespoDRAFT_00953	1.149e-22	102.0	COG1534@1|root,COG1534@2|Bacteria,1Q1JA@1224|Proteobacteria,42W6U@68525|delta/epsilon subdivisions,2WQS8@28221|Deltaproteobacteria,2MKUI@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
GDHHQS3_k127_2039251_6	1047013.AQSP01000131_gene1841	3.622e-83	309.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_2039251_4	1047013.AQSP01000131_gene1840	7.611e-113	393.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS3_k127_2039251_5	1123242.JH636434_gene4022	2.819e-85	288.0	COG2738@1|root,COG2738@2|Bacteria,2IZDM@203682|Planctomycetes	203682|Planctomycetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
GDHHQS3_k127_2039251_0	452637.Oter_3042	6.309e-246	775.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia,3K9NS@414999|Opitutae	414999|Opitutae	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_2039251_3	880073.Calab_2261	2.758e-124	430.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
GDHHQS3_k127_2039251_1	234267.Acid_3593	3.806e-174	576.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_2039251_2	247490.KSU1_B0387	8.52e-130	428.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_2059996_18	1396141.BATP01000040_gene2094	7.78e-06	57.0	COG3091@1|root,COG3091@2|Bacteria,46XI1@74201|Verrucomicrobia,2IVYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SprT homologues.	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
GDHHQS3_k127_2059996_15	1244869.H261_05067	6.084e-15	84.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2UG9E@28211|Alphaproteobacteria,2JY1I@204441|Rhodospirillales	204441|Rhodospirillales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_2059996_0	1303518.CCALI_02898	0.0	1248.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
GDHHQS3_k127_2059996_3	562970.Btus_1313	2.487e-190	610.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,277YF@186823|Alicyclobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_2059996_17	880072.Desac_0033	9.904e-14	84.0	2DN50@1|root,32VJ4@2|Bacteria,1N8HX@1224|Proteobacteria,42VGC@68525|delta/epsilon subdivisions,2WS94@28221|Deltaproteobacteria,2MS7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
GDHHQS3_k127_2059996_9	247490.KSU1_C0524	1.312e-63	239.0	COG3225@1|root,COG3225@2|Bacteria,2J05Q@203682|Planctomycetes	203682|Planctomycetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
GDHHQS3_k127_2059996_11	1254432.SCE1572_14655	2.96e-45	189.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2Z111@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
GDHHQS3_k127_2059996_6	247490.KSU1_C0522	1.031e-90	308.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_2059996_13	330214.NIDE4157	1.173e-23	113.0	COG3824@1|root,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
GDHHQS3_k127_2059996_19	756272.Plabr_0896	0.0001077	53.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
GDHHQS3_k127_2059996_8	324602.Caur_2847	1.393e-76	266.0	COG1015@1|root,COG1015@2|Bacteria,2GA8G@200795|Chloroflexi,375QI@32061|Chloroflexia	32061|Chloroflexia	G	PFAM metalloenzyme domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
GDHHQS3_k127_2059996_12	1340493.JNIF01000003_gene4190	8.184e-27	113.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20,HTH_5
GDHHQS3_k127_2059996_7	1340493.JNIF01000003_gene4191	1.129e-82	283.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_2059996_1	404589.Anae109_2186	9.757e-221	698.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_2059996_14	1479623.JHEL01000015_gene1605	2.699e-19	93.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,4FPHH@85023|Microbacteriaceae	201174|Actinobacteria	J	S4 RNA-binding domain	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
GDHHQS3_k127_2059996_16	340.xcc-b100_0568	7.598e-14	85.0	COG2911@1|root,COG2911@2|Bacteria,1N4HK@1224|Proteobacteria,1SAHK@1236|Gammaproteobacteria,1X9CW@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2059996_5	204669.Acid345_1052	6.942e-123	423.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_2059996_10	234267.Acid_3223	2.031e-52	197.0	28ZVZ@1|root,2ZMKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2059996_2	215803.DB30_7179	5.618e-205	667.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GDHHQS3_k127_2059996_4	670487.Ocepr_0952	8.193e-159	523.0	COG0114@1|root,COG0114@2|Bacteria,1WJ9Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS3_k127_2084535_6	743836.AYNA01000053_gene75	3.387e-52	190.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2UBGF@28211|Alphaproteobacteria,371FE@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_2084535_14	1457250.BBMO01000002_gene2361	1.547e-14	83.0	arCOG03085@1|root,arCOG03085@2157|Archaea,2XZGN@28890|Euryarchaeota,23X0Z@183963|Halobacteria	183963|Halobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
GDHHQS3_k127_2084535_0	751945.Theos_2014	1.258e-166	534.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
GDHHQS3_k127_2084535_7	1449357.JQLK01000001_gene574	8.858e-48	179.0	COG0347@1|root,COG0347@2|Bacteria,1WJZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
GDHHQS3_k127_2084535_3	204669.Acid345_4094	1.297e-70	254.0	COG1834@1|root,COG1834@2|Bacteria,3Y86C@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GDHHQS3_k127_2084535_15	1313172.YM304_37380	5.775e-10	67.0	COG1722@1|root,COG1722@2|Bacteria,2HD2Z@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS3_k127_2084535_4	1313172.YM304_37370	1.206e-61	235.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CNA1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS3_k127_2084535_10	234267.Acid_7266	4.019e-30	139.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
GDHHQS3_k127_2084535_5	1267533.KB906733_gene3501	2.382e-56	217.0	COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria,2JITD@204432|Acidobacteriia	204432|Acidobacteriia	S	Nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
GDHHQS3_k127_2084535_13	1007103.AFHW01000149_gene790	2.375e-19	100.0	COG5528@1|root,COG5528@2|Bacteria,1VW9Q@1239|Firmicutes,4HWSC@91061|Bacilli,26YQB@186822|Paenibacillaceae	91061|Bacilli	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GDHHQS3_k127_2084535_8	1340493.JNIF01000003_gene3955	3.536e-42	168.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
GDHHQS3_k127_2084535_9	344747.PM8797T_04800	1.046e-30	131.0	COG1999@1|root,COG2322@1|root,COG1999@2|Bacteria,COG2322@2|Bacteria,2J00Y@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
GDHHQS3_k127_2084535_2	234267.Acid_4382	5.916e-72	254.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GDHHQS3_k127_2084535_11	1234364.AMSF01000088_gene2781	6.143e-29	135.0	COG1196@1|root,COG4219@1|root,COG1196@2|Bacteria,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria,1T2HB@1236|Gammaproteobacteria,1X552@135614|Xanthomonadales	135614|Xanthomonadales	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
GDHHQS3_k127_2084535_12	1205753.A989_10185	9.757e-29	121.0	COG3682@1|root,COG3682@2|Bacteria,1N3JW@1224|Proteobacteria,1SB84@1236|Gammaproteobacteria,1X73E@135614|Xanthomonadales	135614|Xanthomonadales	K	Methicillin resistance protein	mecI	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GDHHQS3_k127_2084535_1	1121385.AQXW01000004_gene2649	1.167e-122	404.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,ATP-grasp_3,ATP-grasp_4,CPSase_L_D2,GARS_A
GDHHQS3_k127_2086456_26	1445613.JALM01000099_gene4533	6.404e-09	69.0	COG0500@1|root,COG2226@2|Bacteria,2IMHF@201174|Actinobacteria,4DYU7@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_2086456_32	1047013.AQSP01000020_gene1214	0.0001027	55.0	COG1807@1|root,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PMT_2
GDHHQS3_k127_2086456_17	485914.Hmuk_0637	5.806e-39	168.0	COG3119@1|root,arCOG02785@2157|Archaea,2XV54@28890|Euryarchaeota,23UWR@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS3_k127_2086456_24	316278.SynRCC307_0150	3.376e-10	68.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2086456_22	765913.ThidrDRAFT_4139	1.408e-14	74.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,1SHN2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2086456_0	945713.IALB_2724	2.646e-252	808.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GDHHQS3_k127_2086456_20	1499967.BAYZ01000005_gene5436	8.188e-29	135.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
GDHHQS3_k127_2086456_31	997346.HMPREF9374_0390	4.053e-05	57.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HWJ1@91061|Bacilli,27CIP@186824|Thermoactinomycetaceae	91061|Bacilli	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GDHHQS3_k127_2086456_25	710685.MycrhN_1283	1.324e-09	70.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,239HQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
GDHHQS3_k127_2086456_28	1316936.K678_12112	9.327e-08	64.0	COG2755@1|root,COG2755@2|Bacteria,1NYIK@1224|Proteobacteria,2UT1R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2086456_16	443143.GM18_0953	1.881e-39	170.0	2C7PP@1|root,32R7G@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
GDHHQS3_k127_2086456_3	661478.OP10G_1775	4.658e-162	523.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
GDHHQS3_k127_2086456_12	269799.Gmet_1870	7.473e-57	227.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2X98K@28221|Deltaproteobacteria,43T77@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS3_k127_2086456_23	1121946.AUAX01000034_gene6823	2.391e-12	79.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D8QC@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS3_k127_2086456_10	2002.JOEQ01000050_gene8377	1.478e-68	256.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4EG43@85012|Streptosporangiales	2|Bacteria	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784,ko:K20534	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,Glycos_transf_2
GDHHQS3_k127_2086456_21	167548.EU98_1812	7.3e-22	106.0	2E74C@1|root,331NT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
GDHHQS3_k127_2086456_5	1173024.KI912149_gene6199	9.211e-106	363.0	COG0438@1|root,COG0438@2|Bacteria,1G4W4@1117|Cyanobacteria,1JJUK@1189|Stigonemataceae	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_2086456_18	926550.CLDAP_38410	4.923e-34	151.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_2086456_7	1907.SGLAU_01135	1.259e-94	333.0	COG1208@1|root,COG1208@2|Bacteria,2GKHA@201174|Actinobacteria	201174|Actinobacteria	JM	Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_2086456_15	1379270.AUXF01000003_gene3609	1.008e-46	175.0	COG3182@1|root,COG3182@2|Bacteria,1ZUQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
GDHHQS3_k127_2086456_30	251221.35212415	3.924e-05	55.0	COG1266@1|root,COG1266@2|Bacteria,1G3XP@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_2086456_9	207559.Dde_1596	3.384e-74	257.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria,2M9AT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2086456_13	177437.HRM2_18310	1.53e-55	220.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2MM2H@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GDHHQS3_k127_2086456_11	1392488.JHZY01000002_gene1504	3.448e-59	226.0	COG1216@1|root,COG1887@1|root,COG1216@2|Bacteria,COG1887@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia,2XI5H@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
GDHHQS3_k127_2086456_8	443143.GM18_0868	4.108e-94	316.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
GDHHQS3_k127_2086456_2	1121920.AUAU01000033_gene2764	4.509e-172	556.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS3_k127_2086456_27	477974.Daud_1376	2.08e-08	64.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,259GR@186801|Clostridia,2632A@186807|Peptococcaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GDHHQS3_k127_2086456_4	1242864.D187_007752	3.395e-107	385.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS3_k127_2086456_6	338966.Ppro_2304	6.476e-103	352.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,43TP6@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS3_k127_2086456_19	1382359.JIAL01000001_gene595	7.39e-31	126.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS3_k127_2086456_29	796945.HMPREF1145_2169	1.994e-06	54.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,2PSSD@265975|Oribacterium	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS3_k127_2086456_14	1321781.HMPREF1985_02288	2.033e-48	186.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4H3YT@909932|Negativicutes	909932|Negativicutes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS3_k127_2086456_1	1121920.AUAU01000033_gene2756	5.788e-209	669.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_216342_21	234267.Acid_2454	2.758e-29	133.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_2454|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS3_k127_216342_5	234267.Acid_3143	7.139e-180	593.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
GDHHQS3_k127_216342_12	118166.JH976537_gene4031	9.587e-65	252.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
GDHHQS3_k127_216342_3	861299.J421_1872	2.951e-249	778.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_216342_7	251221.35211725	6.181e-109	374.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_216342_14	1379698.RBG1_1C00001G0290	6.158e-57	224.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
GDHHQS3_k127_216342_17	296591.Bpro_0167	6.119e-53	194.0	COG4221@1|root,COG4221@2|Bacteria,1QXBX@1224|Proteobacteria,2WH93@28216|Betaproteobacteria,4AEPB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_216342_20	929703.KE386491_gene4207	8.85e-38	148.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
GDHHQS3_k127_216342_2	1519464.HY22_00255	0.0	1035.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_216342_9	1442599.JAAN01000012_gene126	6.543e-79	268.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,1RY74@1236|Gammaproteobacteria,1X65A@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_216342_25	246197.MXAN_6605	3.939e-10	74.0	COG0443@1|root,COG3170@1|root,COG0443@2|Bacteria,COG3170@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,PilZ
GDHHQS3_k127_216342_10	1142394.PSMK_08370	1.261e-75	279.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_216342_18	795359.TOPB45_0428	3.024e-47	184.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,2GH8K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
GDHHQS3_k127_216342_13	1158182.KB905020_gene1837	6.085e-63	236.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales	135613|Chromatiales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS3_k127_216342_1	314285.KT71_12790	0.0	1188.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,1J9EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_216342_11	105559.Nwat_1280	2.458e-69	252.0	COG0707@1|root,COG0707@2|Bacteria,1QW3F@1224|Proteobacteria,1T2RC@1236|Gammaproteobacteria,1X2NR@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_216342_22	314285.KT71_12245	2.256e-24	120.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Ribosomal_S30AE,Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_216342_8	1117318.PRUB_11196	4.3e-92	332.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
GDHHQS3_k127_216342_0	1128421.JAGA01000003_gene3452	0.0	1303.0	COG0458@1|root,COG0458@2|Bacteria,2NNPB@2323|unclassified Bacteria	2|Bacteria	EF	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
GDHHQS3_k127_216342_19	864702.OsccyDRAFT_1418	2.813e-46	194.0	COG0328@1|root,COG0328@2|Bacteria,1G5V5@1117|Cyanobacteria,1HH8G@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GDHHQS3_k127_216342_4	457398.HMPREF0326_01022	3.554e-224	724.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2M7QQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS3_k127_216342_15	1449357.JQLK01000001_gene2238	4.069e-53	206.0	COG0758@1|root,COG0758@2|Bacteria,1WI08@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,TrmB
GDHHQS3_k127_216342_6	1047013.AQSP01000115_gene336	2.863e-122	435.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
GDHHQS3_k127_216342_16	398767.Glov_2045	4.444e-53	199.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
GDHHQS3_k127_2200155_5	861299.J421_2347	1.379e-74	273.0	COG0531@1|root,COG0531@2|Bacteria,1ZSST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_2200155_11	1288083.AUKR01000001_gene1325	2.675e-40	156.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
GDHHQS3_k127_2200155_2	1267535.KB906767_gene2599	1.635e-86	308.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS3_k127_2200155_7	290397.Adeh_0374	3.875e-51	191.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS3_k127_2200155_10	1158604.I591_02364	6.528e-44	165.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,4B0BN@81852|Enterococcaceae	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS3_k127_2200155_9	1341157.RF007C_09585	1.715e-45	169.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS3_k127_2200155_4	118005.AWNK01000012_gene50	8.54e-76	269.0	COG0052@1|root,COG0052@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS3_k127_2200155_3	1125863.JAFN01000001_gene969	5.775e-85	289.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS3_k127_2200155_1	1232410.KI421418_gene2263	2.872e-91	307.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_2200155_8	1123371.ATXH01000001_gene1313	5.052e-51	188.0	COG0233@1|root,COG0233@2|Bacteria,2GHEC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS3_k127_2200155_13	1267535.KB906767_gene3485	1.144e-26	121.0	COG1211@1|root,COG1211@2|Bacteria,3Y3VR@57723|Acidobacteria,2JI25@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
GDHHQS3_k127_2200155_6	742821.HMPREF9464_00518	7.648e-54	205.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4PQNZ@995019|Sutterellaceae	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GDHHQS3_k127_2200155_12	1262915.BN574_00753	2.3e-37	150.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4H31R@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS3_k127_2200155_0	926560.KE387027_gene1038	1.727e-120	402.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_2200155_14	742817.HMPREF9449_02967	2.534e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_2265117_2	639030.JHVA01000001_gene3374	5.676e-49	179.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJ32@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
GDHHQS3_k127_2265117_0	1123376.AUIU01000002_gene1663	5.883e-279	890.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_2265117_3	243231.GSU3194	3.781e-45	177.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_2265117_1	234267.Acid_5304	3.413e-71	248.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
GDHHQS3_k127_2327605_0	1121013.P873_04890	1.123e-31	136.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_2327605_1	420247.Msm_0372	4.407e-05	57.0	COG1413@1|root,arCOG04653@2157|Archaea,2XUXY@28890|Euryarchaeota,23PZ6@183925|Methanobacteria	183925|Methanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_2346634_34	1499967.BAYZ01000125_gene2598	2.278e-34	148.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
GDHHQS3_k127_2346634_2	1197906.CAJQ02000014_gene332	1.197e-229	734.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,3JRCG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
GDHHQS3_k127_2346634_20	68219.JNXI01000002_gene3959	7.474e-68	241.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_21	68219.JNXI01000002_gene3959	1.053e-65	240.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_53	398767.Glov_2471	0.0005371	47.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	mazE	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
GDHHQS3_k127_2346634_38	879212.DespoDRAFT_02831	5.202e-29	124.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,2MMFJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS3_k127_2346634_18	768066.HELO_3308	3.473e-76	264.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1XJP1@135619|Oceanospirillales	135619|Oceanospirillales	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS3_k127_2346634_36	1123257.AUFV01000008_gene669	1.541e-30	125.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
GDHHQS3_k127_2346634_16	247490.KSU1_C0539	1.985e-82	294.0	COG1538@1|root,COG1538@2|Bacteria,2IZB2@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_2346634_4	247490.KSU1_C0527	7.03e-186	593.0	COG2132@1|root,COG2132@2|Bacteria,2IX3N@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_2346634_28	330214.NIDE0698	2.925e-50	188.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycA	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS3_k127_2346634_30	1045855.DSC_03685	7.86e-39	156.0	COG3544@1|root,COG3544@2|Bacteria,1MVU8@1224|Proteobacteria,1RS42@1236|Gammaproteobacteria,1X70V@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
GDHHQS3_k127_2346634_37	1502852.FG94_00409	1.079e-29	124.0	COG4319@1|root,COG4319@2|Bacteria,1N6PB@1224|Proteobacteria,2WCGM@28216|Betaproteobacteria,477JX@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GDHHQS3_k127_2346634_46	398512.JQKC01000002_gene1732	3.832e-10	69.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes,24X0B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_1	1125863.JAFN01000001_gene1462	3.49e-321	1012.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_2346634_10	234267.Acid_2493	1.805e-115	393.0	COG0457@1|root,COG0457@2|Bacteria,3Y46H@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_35	1038859.AXAU01000026_gene2310	4.106e-32	134.0	COG3678@1|root,COG3678@2|Bacteria,1MZKK@1224|Proteobacteria,2UE6S@28211|Alphaproteobacteria,3K0P9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
GDHHQS3_k127_2346634_47	452637.Oter_4413	4.712e-10	67.0	COG0845@1|root,COG0845@2|Bacteria,46WQR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
GDHHQS3_k127_2346634_0	234267.Acid_7514	0.0	1349.0	COG3696@1|root,COG3696@2|Bacteria,3Y3AQ@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
GDHHQS3_k127_2346634_14	1125863.JAFN01000001_gene1439	1.818e-85	315.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
GDHHQS3_k127_2346634_43	1121920.AUAU01000013_gene1726	7.507e-17	94.0	COG1538@1|root,COG1538@2|Bacteria,3Y54R@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_2346634_27	869210.Marky_1948	4.836e-51	207.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_2346634_45	1307759.JOMJ01000003_gene2301	6.189e-12	78.0	COG0470@1|root,COG0470@2|Bacteria,1REVP@1224|Proteobacteria,42RHQ@68525|delta/epsilon subdivisions,2WNNE@28221|Deltaproteobacteria,2M89K@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
GDHHQS3_k127_2346634_26	269799.Gmet_2318	7.267e-54	199.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS3_k127_2346634_49	1144275.COCOR_00143	4.381e-08	65.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_2346634_39	391008.Smal_2942	2.442e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,1S2IU@1236|Gammaproteobacteria,1XC71@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2346634_44	1449049.JONW01000006_gene3165	2.756e-14	86.0	298RU@1|root,2ZVW4@2|Bacteria,1NYXC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_13	883126.HMPREF9710_04171	1.168e-97	330.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria,473X7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Integral membrane protein TerC family	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS3_k127_2346634_23	1123279.ATUS01000005_gene3140	2.57e-61	221.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1J4IP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_2346634_9	1215092.PA6_035_00030	3.115e-128	418.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1YDVM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_2346634_22	215803.DB30_5710	1.172e-62	234.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2WNCT@28221|Deltaproteobacteria,2YYDE@29|Myxococcales	28221|Deltaproteobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS3_k127_2346634_15	504472.Slin_5436	1.059e-82	301.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,47KCU@768503|Cytophagia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
GDHHQS3_k127_2346634_12	1496688.ER33_10790	4.193e-103	355.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,22RU2@167375|Cyanobium	1117|Cyanobacteria	C	NADP transhydrogenase	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
GDHHQS3_k127_2346634_3	1089550.ATTH01000001_gene1799	6.253e-216	715.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,4NGW0@976|Bacteroidetes,1FIUK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
GDHHQS3_k127_2346634_32	861299.J421_0735	7.816e-36	147.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0735|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	-
GDHHQS3_k127_2346634_19	1123242.JH636435_gene2917	4.327e-68	258.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_2346634_11	215803.DB30_3071	9.749e-110	398.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WYNH@28221|Deltaproteobacteria,2YZIM@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2346634_29	935863.AWZR01000013_gene1524	7.509e-39	169.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,P_proprotein,Peptidase_S8
GDHHQS3_k127_2346634_5	765912.Thimo_2580	4.906e-174	562.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_2346634_24	1116472.MGMO_98c00160	1.463e-58	226.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XFQY@135618|Methylococcales	135618|Methylococcales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS3_k127_2346634_40	685778.AORL01000021_gene922	1.264e-19	98.0	2ES5B@1|root,33JQ4@2|Bacteria,1NHPR@1224|Proteobacteria,2UN83@28211|Alphaproteobacteria,2K67H@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_2346634_31	685778.AORL01000021_gene921	3.625e-37	161.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,2K4M1@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2346634_48	1227484.C471_15652	1.837e-09	65.0	COG3794@1|root,arCOG02921@2157|Archaea,2XZ0D@28890|Euryarchaeota,23WZS@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	hcp1	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,TAT_signal
GDHHQS3_k127_2346634_6	204669.Acid345_1391	2.432e-169	539.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_2346634_7	903818.KI912268_gene3152	1.369e-142	464.0	COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
GDHHQS3_k127_2346634_17	243231.GSU1494	2.866e-78	294.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,43BPZ@68525|delta/epsilon subdivisions,2X717@28221|Deltaproteobacteria,43TK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase PilS, PAS domain-containing	pilS	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4
GDHHQS3_k127_2346634_8	1232410.KI421416_gene2592	2.906e-141	462.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_2346634_25	661478.OP10G_1759	1.217e-55	225.0	COG1162@1|root,COG1162@2|Bacteria	2|Bacteria	S	GTPase activity	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase,RsgA_N
GDHHQS3_k127_2346634_42	926566.Terro_3942	8.422e-18	89.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_2346634_41	215803.DB30_1649	1.534e-18	95.0	COG0745@1|root,COG0745@2|Bacteria,1QX4W@1224|Proteobacteria,43BXK@68525|delta/epsilon subdivisions,2X78D@28221|Deltaproteobacteria,2YZQQ@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
GDHHQS3_k127_2346634_50	272943.RSP_1998	4.434e-08	59.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,1FCP3@1060|Rhodobacter	28211|Alphaproteobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS3_k127_2384744_15	1382356.JQMP01000004_gene319	8.244e-43	161.0	COG3653@1|root,COG3653@2|Bacteria,2G86A@200795|Chloroflexi,27ZD5@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_2384744_8	1123073.KB899241_gene3145	3.045e-99	340.0	COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,1XCF4@135614|Xanthomonadales	135614|Xanthomonadales	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
GDHHQS3_k127_2384744_14	227882.SAV_548	6.027e-61	235.0	2AQUC@1|root,31G2H@2|Bacteria,2IET7@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
GDHHQS3_k127_2384744_24	316274.Haur_2505	9.091e-15	84.0	2DV6Q@1|root,32UYT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2384744_1	448385.sce8281	1.079e-177	576.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS3_k127_2384744_23	269799.Gmet_0202	6.255e-15	80.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1QXMY@1224|Proteobacteria,42W3X@68525|delta/epsilon subdivisions,2WTS7@28221|Deltaproteobacteria,43TUJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Motility response receiver histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_2384744_4	452637.Oter_1512	8.444e-123	424.0	COG0577@1|root,COG0577@2|Bacteria,46YY4@74201|Verrucomicrobia,3K9RN@414999|Opitutae	414999|Opitutae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2384744_3	452637.Oter_1513	2.039e-128	424.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_2384744_7	1396141.BATP01000042_gene1897	1.921e-99	330.0	COG1136@1|root,COG1136@2|Bacteria,46UWZ@74201|Verrucomicrobia,2IVI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_2384744_6	452637.Oter_1515	3.683e-100	340.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GDHHQS3_k127_2384744_9	368407.Memar_1916	2.061e-98	349.0	COG0019@1|root,arCOG02268@2157|Archaea,2XSY8@28890|Euryarchaeota,2N93Z@224756|Methanomicrobia	224756|Methanomicrobia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS3_k127_2384744_11	330214.NIDE0244	1.675e-74	275.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
GDHHQS3_k127_2384744_18	290397.Adeh_2514	1.268e-33	134.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2Z24M@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_2384744_17	338966.Ppro_1190	1.193e-37	154.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,43UJ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS3_k127_2384744_0	1242864.D187_000141	0.0	1135.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2YU96@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_2384744_19	502025.Hoch_0331	4.347e-33	139.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
GDHHQS3_k127_2384744_13	404589.Anae109_1699	1.388e-64	236.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
GDHHQS3_k127_2384744_22	1128421.JAGA01000003_gene2958	1.765e-21	107.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_2384744_25	1434325.AZQN01000003_gene2356	3.784e-14	83.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
GDHHQS3_k127_2384744_12	861299.J421_2443	6.577e-74	257.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GDHHQS3_k127_2384744_10	1463821.JOGR01000011_gene2108	7.253e-86	292.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4EZKW@85014|Glycomycetales	201174|Actinobacteria	S	KR domain	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
GDHHQS3_k127_2384744_26	643867.Ftrac_1618	2.64e-05	51.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
GDHHQS3_k127_2384744_27	935567.JAES01000028_gene2705	4.851e-05	50.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales	135614|Xanthomonadales	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
GDHHQS3_k127_2384744_2	1125863.JAFN01000001_gene394	3.623e-156	503.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS3_k127_2384744_21	1385518.N798_12660	2.007e-22	110.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4FG1C@85021|Intrasporangiaceae	201174|Actinobacteria	D	chromosome partitioning	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
GDHHQS3_k127_2384744_5	1168065.DOK_06382	4.375e-120	403.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1J7YG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	FHA,T2SSE
GDHHQS3_k127_2384744_16	1168065.DOK_06387	1.013e-37	160.0	COG4965@1|root,COG4965@2|Bacteria,1N415@1224|Proteobacteria	1224|Proteobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
GDHHQS3_k127_2384744_20	1168065.DOK_06392	3.634e-31	141.0	COG2064@1|root,COG2064@2|Bacteria,1QEG1@1224|Proteobacteria,1S9F4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
GDHHQS3_k127_2399686_4	1047013.AQSP01000124_gene2676	9.452e-92	332.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GDHHQS3_k127_2399686_10	1047013.AQSP01000124_gene2678	1.136e-26	122.0	COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria	2|Bacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GDHHQS3_k127_2399686_14	1125863.JAFN01000001_gene2286	8.114e-14	81.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
GDHHQS3_k127_2399686_3	243231.GSU2032	3.052e-105	352.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43UK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GDHHQS3_k127_2399686_13	431943.CKL_1380	3.686e-14	85.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,36MTX@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
GDHHQS3_k127_2399686_0	204669.Acid345_0175	3.006e-225	720.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS3_k127_2399686_6	1267533.KB906734_gene4323	6.798e-80	282.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_2399686_1	118005.AWNK01000010_gene361	1.326e-120	409.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_2399686_12	667014.Thein_0822	2.583e-21	98.0	COG1862@1|root,COG1862@2|Bacteria,2GHYH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GDHHQS3_k127_2399686_2	1150469.RSPPHO_00318	2.529e-113	390.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2JPNV@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS3_k127_2399686_15	690850.Desaf_3671	9.186e-09	68.0	COG2834@1|root,COG2834@2|Bacteria,1N3XP@1224|Proteobacteria,42TP4@68525|delta/epsilon subdivisions,2WQR3@28221|Deltaproteobacteria,2MCRD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
GDHHQS3_k127_2399686_16	378806.STAUR_6385	8.224e-08	64.0	28S5K@1|root,2ZEH5@2|Bacteria,1PW2U@1224|Proteobacteria,434UQ@68525|delta/epsilon subdivisions,2WZ5T@28221|Deltaproteobacteria,2Z1DY@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
GDHHQS3_k127_2399686_9	316278.SynRCC307_0223	1.648e-27	119.0	COG0801@1|root,COG0801@2|Bacteria,1G5NF@1117|Cyanobacteria,1H103@1129|Synechococcus	1117|Cyanobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GDHHQS3_k127_2399686_7	521460.Athe_2262	4.984e-62	240.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia,42IKP@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
GDHHQS3_k127_2399686_5	941449.dsx2_0858	2.348e-86	295.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2M9EG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS3_k127_2399686_11	1142394.PSMK_25540	3.495e-24	115.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
GDHHQS3_k127_2399686_8	1121920.AUAU01000010_gene125	1.188e-44	174.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_2462060_10	1267535.KB906767_gene1586	3.21e-35	140.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_2462060_5	1128421.JAGA01000003_gene2872	1.811e-56	203.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GDHHQS3_k127_2462060_2	1128421.JAGA01000003_gene2871	4.673e-190	640.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
GDHHQS3_k127_2462060_1	204669.Acid345_3003	3.125e-305	978.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria,2JI83@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
GDHHQS3_k127_2462060_3	525904.Tter_1596	1.63e-82	280.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
GDHHQS3_k127_2462060_4	649638.Trad_2690	5.328e-74	260.0	COG4947@1|root,COG4947@2|Bacteria,1WMMQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS3_k127_2462060_9	1396418.BATQ01000047_gene6186	4.913e-37	155.0	2DECI@1|root,32U34@2|Bacteria,46WCA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GDHHQS3_k127_2462060_12	1173028.ANKO01000112_gene4868	4.579e-17	88.0	2E7MG@1|root,3323C@2|Bacteria,1GCRI@1117|Cyanobacteria,1HFKH@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS3_k127_2462060_13	1296415.JACC01000022_gene4159	3.436e-15	88.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
GDHHQS3_k127_2462060_7	1173028.ANKO01000112_gene4871	6.625e-45	183.0	COG1216@1|root,COG1216@2|Bacteria,1G2A7@1117|Cyanobacteria,1H9SV@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
GDHHQS3_k127_2462060_8	671143.DAMO_2980	3.599e-37	158.0	COG1216@1|root,COG1216@2|Bacteria,2NP6P@2323|unclassified Bacteria	2|Bacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2462060_6	65393.PCC7424_0327	3.786e-48	192.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3KHZQ@43988|Cyanothece	1117|Cyanobacteria	H	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
GDHHQS3_k127_2462060_11	1047013.AQSP01000131_gene1799	7.41e-23	108.0	28MUS@1|root,2ZB2I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
GDHHQS3_k127_2462060_0	483219.LILAB_22600	0.0	1290.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
GDHHQS3_k127_2565434_1	1128421.JAGA01000002_gene1351	8.33e-73	260.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_2565434_0	518766.Rmar_2716	3.548e-99	338.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1FIY6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase like family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2566869_2	1183438.GKIL_4354	5.66e-167	560.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_2566869_16	1183438.GKIL_4353	2.937e-26	111.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_2566869_11	1047013.AQSP01000101_gene615	4.435e-54	209.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Gp58
GDHHQS3_k127_2566869_7	1300345.LF41_877	4.76e-74	261.0	COG3315@1|root,COG3315@2|Bacteria,1RG18@1224|Proteobacteria,1TCTK@1236|Gammaproteobacteria,1X9S9@135614|Xanthomonadales	135614|Xanthomonadales	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
GDHHQS3_k127_2566869_0	234267.Acid_2611	1.207e-234	759.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_2566869_14	234267.Acid_2610	1.98e-35	142.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_2566869_4	1379270.AUXF01000002_gene1132	7.47e-102	338.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
GDHHQS3_k127_2566869_6	118161.KB235922_gene564	8.561e-78	282.0	COG2072@1|root,COG2072@2|Bacteria,1G5HN@1117|Cyanobacteria,3VKCG@52604|Pleurocapsales	1117|Cyanobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
GDHHQS3_k127_2566869_10	861299.J421_0863	1.463e-56	208.0	COG1216@1|root,COG1216@2|Bacteria,1ZV2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2566869_15	765910.MARPU_07495	1.977e-27	131.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_2566869_3	448385.sce6682	6.828e-132	442.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS3_k127_2566869_8	1163407.UU7_05623	1.605e-68	259.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	yrgI	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS3_k127_2566869_1	886293.Sinac_0199	3.362e-182	581.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_2566869_17	1121877.JQKF01000018_gene2523	7.315e-07	59.0	COG4242@1|root,COG4242@2|Bacteria,2HGPS@201174|Actinobacteria,4CNS6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS3_k127_2566869_9	1396141.BATP01000039_gene1393	8.688e-59	209.0	COG1225@1|root,COG1225@2|Bacteria,46VGB@74201|Verrucomicrobia,2IUU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_2566869_12	234267.Acid_3376	9.636e-46	169.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria	57723|Acidobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS3_k127_2566869_5	1144275.COCOR_06495	6.49e-94	329.0	COG0491@1|root,COG0494@1|root,COG0491@2|Bacteria,COG0494@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
GDHHQS3_k127_2566869_13	666685.R2APBS1_2584	3.586e-43	161.0	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS3_k127_2576219_0	234267.Acid_0585	2.9e-153	519.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_2576219_1	234267.Acid_3325	2.061e-19	104.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_2653650_2	1280001.BAOA01000057_gene4550	7.711e-30	127.0	28IAE@1|root,2Z8D0@2|Bacteria,1NC6U@1224|Proteobacteria,1RSEY@1236|Gammaproteobacteria,1XVC4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2653650_3	1034943.BN1094_03618	1.959e-13	82.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2653650_1	404589.Anae109_3496	8.045e-102	344.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS3_k127_2653650_0	1384056.N787_06350	7.735e-133	432.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1X3D0@135614|Xanthomonadales	135614|Xanthomonadales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS3_k127_26850_62	1380390.JIAT01000010_gene3953	1.039e-07	62.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_26850_1	220664.PFL_4314	5.379e-277	875.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1YPD6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_26850_2	2340.JV46_17100	3.118e-269	853.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1J4W4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS3_k127_26850_46	379066.GAU_0815	6.784e-32	138.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GDHHQS3_k127_26850_26	196490.AUEZ01000027_gene1714	3.125e-71	254.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,3JUE8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GDHHQS3_k127_26850_11	204669.Acid345_0001	1.653e-120	426.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia	204432|Acidobacteriia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS3_k127_26850_18	2002.JOEQ01000012_gene5771	9.134e-91	321.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4EHD6@85012|Streptosporangiales	201174|Actinobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS3_k127_26850_28	448385.sce3935	3.906e-68	245.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GDHHQS3_k127_26850_49	215803.DB30_7168	4.979e-21	105.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS3_k127_26850_54	1278073.MYSTI_02245	4.642e-18	96.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS3_k127_26850_27	56780.SYN_02701	2.08e-68	244.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS3_k127_26850_34	391625.PPSIR1_24934	2.267e-56	204.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1099	AAA_28,Thymidylate_kin
GDHHQS3_k127_26850_14	316274.Haur_2569	3.965e-100	343.0	COG0160@1|root,COG0160@2|Bacteria,2G5RV@200795|Chloroflexi,3763X@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_26850_29	264732.Moth_0029	4.799e-65	241.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
GDHHQS3_k127_26850_50	204669.Acid345_1974	6.533e-20	105.0	COG0718@1|root,COG0718@2|Bacteria,3Y5CB@57723|Acidobacteria,2JJRM@204432|Acidobacteriia	204432|Acidobacteriia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GDHHQS3_k127_26850_22	335543.Sfum_2789	9.306e-80	292.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MQ7N@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS3_k127_26850_37	352165.HMPREF7215_0598	6.803e-53	191.0	COG0590@1|root,COG0590@2|Bacteria,3TB5H@508458|Synergistetes	508458|Synergistetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
GDHHQS3_k127_26850_57	1191523.MROS_1138	2.688e-14	74.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GDHHQS3_k127_26850_55	266117.Rxyl_3215	3.498e-16	84.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GDHHQS3_k127_26850_53	643562.Daes_2574	9.163e-19	93.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2WRIM@28221|Deltaproteobacteria,2MD5H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GDHHQS3_k127_26850_24	1047013.AQSP01000133_gene2153	3.756e-76	278.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GDHHQS3_k127_26850_64	867903.ThesuDRAFT_00474	4.952e-07	63.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WCNH@538999|Clostridiales incertae sedis	186801|Clostridia	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GDHHQS3_k127_26850_42	1476583.DEIPH_ctg052orf0096	6.105e-41	155.0	2DZT4@1|root,32VI7@2|Bacteria,1WMUG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_26850_52	177439.DP1283	5.312e-19	95.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2WPKF@28221|Deltaproteobacteria,2MJSC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GDHHQS3_k127_26850_21	1125863.JAFN01000001_gene2683	3.274e-82	284.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_26850_32	398767.Glov_3176	5.704e-59	226.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43U5F@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ParB domain protein nuclease	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GDHHQS3_k127_26850_51	1122917.KB899663_gene2508	2.306e-19	89.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,4HDVQ@91061|Bacilli,26SD2@186822|Paenibacillaceae	91061|Bacilli	S	tRNA-splicing ligase RtcB	hint	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GDHHQS3_k127_26850_43	1479237.JMLY01000001_gene1526	1.179e-35	153.0	COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_26850_31	267608.RSp0710	1.638e-60	227.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,1K5U4@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_26850_45	382464.ABSI01000011_gene2976	7.827e-35	145.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_26850_30	1342302.JASC01000003_gene3623	1.631e-63	239.0	COG3488@1|root,COG3488@2|Bacteria,1Q802@1224|Proteobacteria,2VE5R@28211|Alphaproteobacteria,3ZYW4@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Thiol oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_26850_40	1469607.KK073768_gene1550	1.146e-51	209.0	COG0348@1|root,COG0664@1|root,COG0348@2|Bacteria,COG0664@2|Bacteria,1FZVX@1117|Cyanobacteria,1HKSY@1161|Nostocales	1117|Cyanobacteria	C	cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Fer4_5,cNMP_binding
GDHHQS3_k127_26850_63	378806.STAUR_1281	2.176e-07	64.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_26850_48	243231.GSU0691	4.446e-23	102.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,42TW6@68525|delta/epsilon subdivisions,2WQNT@28221|Deltaproteobacteria,43SNP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GDHHQS3_k127_26850_3	269799.Gmet_1766	2.065e-262	821.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,43UJT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS3_k127_26850_4	518766.Rmar_0089	2.126e-208	683.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_26850_9	1254432.SCE1572_33570	1.433e-142	457.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
GDHHQS3_k127_26850_12	1254432.SCE1572_33565	1.881e-110	374.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GDHHQS3_k127_26850_16	760192.Halhy_0227	2.492e-95	332.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IT3V@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE
GDHHQS3_k127_26850_15	452637.Oter_0699	3.594e-99	342.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
GDHHQS3_k127_26850_68	1267535.KB906767_gene4160	0.0005007	53.0	COG2304@1|root,COG2304@2|Bacteria,3Y99W@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GDHHQS3_k127_26850_44	1122201.AUAZ01000008_gene438	2.872e-35	142.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,468R1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
GDHHQS3_k127_26850_23	243233.MCA0072	1.973e-77	274.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XEER@135618|Methylococcales	135618|Methylococcales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GDHHQS3_k127_26850_5	1041159.AZUW01000009_gene4518	1.265e-180	571.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,2VGDJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_26850_6	1049564.TevJSym_af00690	9.159e-168	552.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,1RNTD@1236|Gammaproteobacteria,1J9TP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
GDHHQS3_k127_26850_25	1121920.AUAU01000011_gene189	2.488e-75	285.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
GDHHQS3_k127_26850_13	644966.Tmar_2110	2.531e-104	349.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GDHHQS3_k127_26850_8	240015.ACP_1006	5.35e-149	481.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_26850_0	215803.DB30_3844	0.0	1342.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,438QJ@68525|delta/epsilon subdivisions,2X3XW@28221|Deltaproteobacteria,2YXIE@29|Myxococcales	28221|Deltaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS3_k127_26850_59	215803.DB30_4761	1.915e-09	70.0	COG1164@1|root,COG1164@2|Bacteria,1Q2ZB@1224|Proteobacteria,438NR@68525|delta/epsilon subdivisions,2X8TB@28221|Deltaproteobacteria,2YXCV@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_26850_47	933801.Ahos_1406	4.279e-23	103.0	COG1324@1|root,arCOG04231@2157|Archaea,2XR9J@28889|Crenarchaeota	28889|Crenarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GDHHQS3_k127_26850_56	502025.Hoch_5823	1.438e-15	83.0	COG1555@1|root,COG1555@2|Bacteria,1Q1BE@1224|Proteobacteria,43764@68525|delta/epsilon subdivisions,2X24M@28221|Deltaproteobacteria,2Z2UP@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
GDHHQS3_k127_26850_39	760142.Hipma_0930	4.185e-52	192.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M69Y@213113|Desulfurellales	28221|Deltaproteobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GDHHQS3_k127_26850_36	404589.Anae109_0480	3.847e-53	207.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS3_k127_26850_17	1121403.AUCV01000004_gene2028	1.666e-93	326.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MIHH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_26850_41	1125863.JAFN01000001_gene358	2.406e-43	171.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GDHHQS3_k127_26850_60	1121438.JNJA01000001_gene2516	4.259e-09	69.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2M8ME@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_26850_35	1144275.COCOR_05264	1.704e-53	207.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,43C9M@68525|delta/epsilon subdivisions,2X83G@28221|Deltaproteobacteria,2Z3K6@29|Myxococcales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
GDHHQS3_k127_26850_19	765698.Mesci_5880	1.517e-88	302.0	COG1662@1|root,COG1662@2|Bacteria,1MV8R@1224|Proteobacteria,2TURN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1,DDE_Tnp_IS240
GDHHQS3_k127_26850_67	1125863.JAFN01000001_gene3525	0.0003959	49.0	COG4679@1|root,COG4679@2|Bacteria,1NCYI@1224|Proteobacteria,438R4@68525|delta/epsilon subdivisions,2WY6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS3_k127_26850_66	1335757.SPICUR_09185	1.047e-05	54.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	MA20_23000	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS3_k127_26850_58	671143.DAMO_1330	9.749e-14	74.0	2EUJ6@1|root,33N15@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_26850_10	1144275.COCOR_07209	6.191e-139	452.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GDHHQS3_k127_26850_38	1122611.KB903968_gene2299	2.805e-52	194.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,4EJ8K@85012|Streptosporangiales	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
GDHHQS3_k127_26850_7	378806.STAUR_1258	4.197e-161	533.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria,2YUJE@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
GDHHQS3_k127_26850_20	886293.Sinac_7280	9.897e-88	323.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_26850_33	479431.Namu_5117	3.807e-57	220.0	COG0644@1|root,COG0644@2|Bacteria,2GM2M@201174|Actinobacteria,4EUUC@85013|Frankiales	201174|Actinobacteria	C	FAD dependent oxidoreductase	srsC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
GDHHQS3_k127_2796962_4	1177154.Y5S_03470	0.0005446	45.0	COG0824@1|root,COG0824@2|Bacteria,1RH20@1224|Proteobacteria,1S6RE@1236|Gammaproteobacteria,1XS86@135619|Oceanospirillales	135619|Oceanospirillales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS3_k127_2796962_3	298654.FraEuI1c_1806	0.0004272	54.0	COG3975@1|root,COG3975@2|Bacteria,2I2Y7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2796962_1	543728.Vapar_6380	7.514e-15	82.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VR5K@28216|Betaproteobacteria,4ABQH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2796962_2	713587.THITH_13260	9.65e-10	70.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S6MH@1236|Gammaproteobacteria,1X2FJ@135613|Chromatiales	135613|Chromatiales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_2796962_0	290397.Adeh_1128	2.532e-34	144.0	COG0697@1|root,COG0697@2|Bacteria,1MX1Y@1224|Proteobacteria,42NTW@68525|delta/epsilon subdivisions,2WMEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_2849259_1	1031288.AXAA01000004_gene1867	3.848e-47	182.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,36F6R@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GDHHQS3_k127_2849259_2	1276756.AUEX01000010_gene1634	0.0004758	53.0	COG5652@1|root,COG5652@2|Bacteria,1N9QA@1224|Proteobacteria,2VW74@28216|Betaproteobacteria,4AFP6@80864|Comamonadaceae	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS3_k127_2849259_0	945713.IALB_0729	1.192e-137	444.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GDHHQS3_k127_2850716_2	1123367.C666_07225	9.662e-87	294.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS3_k127_2850716_5	566466.NOR53_1623	9.981e-46	176.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1J5CD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS3_k127_2850716_4	886293.Sinac_2076	2.212e-46	172.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GDHHQS3_k127_2850716_3	1536769.P40081_32455	3.645e-67	241.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_2850716_0	429009.Adeg_0063	4.837e-128	419.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42FEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_2850716_6	1209989.TepiRe1_2280	3.386e-24	107.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS3_k127_2850716_7	765420.OSCT_0776	8.277e-06	56.0	COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_2850716_1	414684.RC1_3003	2.997e-119	396.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2JQA2@204441|Rhodospirillales	204441|Rhodospirillales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
GDHHQS3_k127_2854503_0	224911.27350855	0.0	1622.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWQB@28211|Alphaproteobacteria,3JQWC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	MA20_07280	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_2854503_39	880072.Desac_1307	2.516e-23	104.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_2854503_33	1089550.ATTH01000001_gene2218	5.221e-47	181.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_2854503_38	331869.BAL199_29882	4.139e-26	125.0	29EN4@1|root,301K2@2|Bacteria,1RD2A@1224|Proteobacteria,2U7UG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2854503_16	489825.LYNGBM3L_01310	3.418e-116	397.0	COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria,1G2B0@1117|Cyanobacteria,1HHGE@1150|Oscillatoriales	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct,Rieske
GDHHQS3_k127_2854503_42	111781.Lepto7376_2306	1.558e-09	68.0	2E14K@1|root,32WJQ@2|Bacteria,1G825@1117|Cyanobacteria,1HGGM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2854503_7	644966.Tmar_1963	1.769e-151	512.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,3WCYU@538999|Clostridiales incertae sedis	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_2854503_37	1396418.BATQ01000154_gene1025	5.233e-27	122.0	2EMW0@1|root,33FI8@2|Bacteria,46WXX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2854503_34	861299.J421_0777	8.664e-43	162.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
GDHHQS3_k127_2854503_21	266117.Rxyl_3164	1.642e-81	280.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS3_k127_2854503_28	243231.GSU2396	1.05e-56	203.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,43SJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS3_k127_2854503_41	1198114.AciX9_1475	6.938e-10	71.0	COG3595@1|root,COG3595@2|Bacteria,3Y4HG@57723|Acidobacteria,2JJ7G@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_2854503_3	378806.STAUR_3955	7.918e-281	912.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
GDHHQS3_k127_2854503_25	378806.STAUR_4413	2.346e-62	231.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2X282@28221|Deltaproteobacteria,2YV1K@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_2854503_18	215803.DB30_6949	3.09e-108	370.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WN4R@28221|Deltaproteobacteria,2YVY4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_2854503_1	215803.DB30_6948	0.0	1387.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GDHHQS3_k127_2854503_24	96561.Dole_1367	1.497e-66	250.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
GDHHQS3_k127_2854503_32	1403819.BATR01000163_gene5492	3.526e-52	199.0	2BYUR@1|root,32TV8@2|Bacteria,46V5C@74201|Verrucomicrobia,2IVA6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2854503_22	1123371.ATXH01000032_gene462	3.589e-73	266.0	COG0477@1|root,COG2814@2|Bacteria,2GHE9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EGP	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
GDHHQS3_k127_2854503_30	1254432.SCE1572_37980	2.083e-54	198.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RQR@68525|delta/epsilon subdivisions,2WNTF@28221|Deltaproteobacteria,2Z0PC@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS3_k127_2854503_36	290315.Clim_2377	9.215e-28	130.0	COG0400@1|root,COG0400@2|Bacteria,1FF1R@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
GDHHQS3_k127_2854503_9	290397.Adeh_1619	5.18e-133	451.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2YU2Z@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS3_k127_2854503_13	1232410.KI421413_gene593	3.99e-121	397.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_2854503_26	1392502.JNIO01000008_gene2287	5.626e-59	212.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes	909932|Negativicutes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GDHHQS3_k127_2854503_2	1042377.AFPJ01000030_gene436	0.0	1159.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_2854503_15	235909.GK1193	2.781e-116	417.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1WE4P@129337|Geobacillus	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS3_k127_2854503_10	1384054.N790_09790	2.414e-124	419.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,1X5X9@135614|Xanthomonadales	135614|Xanthomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_2854503_40	1313421.JHBV01000008_gene4376	4.183e-11	74.0	2CRMH@1|root,32SPB@2|Bacteria,4NTBB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569,DinB_2
GDHHQS3_k127_2854503_23	429009.Adeg_0304	1.046e-72	256.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_2854503_20	1121430.JMLG01000019_gene1646	1.442e-92	318.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS3_k127_2854503_17	1121920.AUAU01000005_gene1113	8.837e-109	362.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_2854503_11	13035.Dacsa_0867	2.424e-123	428.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
GDHHQS3_k127_2854503_6	880073.Calab_3584	1.212e-157	511.0	COG0297@1|root,COG0297@2|Bacteria,2NQKG@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GDHHQS3_k127_2854503_4	502025.Hoch_5176	8.186e-184	598.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_2854503_29	998674.ATTE01000001_gene4034	7.729e-55	211.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,460JU@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the bacterial glucokinase family	-	-	-	-	-	-	-	-	-	-	-	-	Glucokinase
GDHHQS3_k127_2854503_35	316067.Geob_1205	4.894e-32	130.0	COG0824@1|root,COG0824@2|Bacteria,1PF7Z@1224|Proteobacteria,42SV4@68525|delta/epsilon subdivisions,2WPY3@28221|Deltaproteobacteria,43SSY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GDHHQS3_k127_2854503_12	1385521.N803_02065	5.038e-122	404.0	COG0189@1|root,COG0189@2|Bacteria,2I5WV@201174|Actinobacteria,4FF3F@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2854503_14	710696.Intca_0098	1.838e-119	406.0	COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
GDHHQS3_k127_2854503_31	1380393.JHVP01000005_gene3586	3.658e-54	201.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS3_k127_2854503_5	1032480.MLP_53060	1.456e-168	539.0	COG0151@1|root,COG0151@2|Bacteria,2I4MA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_3,ATP-grasp_4,Dala_Dala_lig_C
GDHHQS3_k127_2854503_8	1306174.JODP01000005_gene1294	2.121e-147	491.0	COG1523@1|root,COG1523@2|Bacteria,2GWU2@201174|Actinobacteria	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
GDHHQS3_k127_2854503_19	530564.Psta_0806	1.082e-102	340.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS3_k127_2891989_5	926569.ANT_19710	9.225e-09	57.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS3_k127_2891989_4	1269813.ATUL01000023_gene653	2.3e-21	102.0	COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales	135613|Chromatiales	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_2891989_1	671143.DAMO_2141	1.108e-46	177.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
GDHHQS3_k127_2891989_2	502025.Hoch_3524	1.681e-46	175.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS3_k127_2891989_3	1123060.JONP01000003_gene269	1.43e-26	124.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2JPUZ@204441|Rhodospirillales	204441|Rhodospirillales	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084,ko:K08344	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS3_k127_2891989_0	649638.Trad_1658	2.968e-90	323.0	COG2366@1|root,COG2366@2|Bacteria,1WJ3J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	peptidase S45, penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS3_k127_3023005_14	575540.Isop_0364	6.821e-101	334.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,2J033@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Oxidored_q6
GDHHQS3_k127_3023005_4	404380.Gbem_3188	3.107e-171	581.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS3_k127_3023005_8	290397.Adeh_3658	6.999e-149	484.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2YZXM@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
GDHHQS3_k127_3023005_26	338966.Ppro_0338	6.962e-46	188.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,42NDW@68525|delta/epsilon subdivisions,2WMF0@28221|Deltaproteobacteria,43SXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	hydrogenase 4 membrane	ehrC	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
GDHHQS3_k127_3023005_17	316067.Geob_1703	5.425e-80	299.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2600	NADHdh
GDHHQS3_k127_3023005_5	1232410.KI421427_gene1299	5.074e-171	559.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_3023005_0	313606.M23134_07566	6.055e-320	1016.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_3023005_23	204669.Acid345_3020	1.84e-47	182.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_19	1089547.KB913013_gene1453	4.982e-78	271.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,47KYF@768503|Cytophagia	976|Bacteroidetes	S	PFAM ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_3023005_20	639030.JHVA01000001_gene3309	2.103e-71	269.0	COG1668@1|root,COG1668@2|Bacteria,3Y2XV@57723|Acidobacteria,2JIQK@204432|Acidobacteriia	204432|Acidobacteriia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_3023005_3	296591.Bpro_2461	1.829e-172	563.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,4ADN4@80864|Comamonadaceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_3023005_24	1403819.BATR01000092_gene2820	6.611e-47	182.0	2E3CB@1|root,32YBM@2|Bacteria,46W9H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
GDHHQS3_k127_3023005_2	497964.CfE428DRAFT_6499	1.813e-221	720.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_3023005_9	926550.CLDAP_11720	1.178e-147	481.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_3023005_18	666685.R2APBS1_1154	1.318e-79	293.0	COG3055@1|root,COG3055@2|Bacteria,1NHAC@1224|Proteobacteria,1RYBY@1236|Gammaproteobacteria,1XAGU@135614|Xanthomonadales	135614|Xanthomonadales	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_28	1121920.AUAU01000005_gene933	2.997e-24	109.0	2EKGK@1|root,33E6M@2|Bacteria	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_3023005_31	1379270.AUXF01000003_gene3833	8.267e-14	75.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	1.14.19.20	ko:K00227	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101,M00102	R07215,R07486,R07491,R07505	RC00904	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
GDHHQS3_k127_3023005_10	1300345.LF41_901	2.21e-139	465.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XDED@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
GDHHQS3_k127_3023005_37	1521187.JPIM01000015_gene3738	2.069e-05	51.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS3_k127_3023005_30	566466.NOR53_517	1.161e-19	100.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Phenol_MetA_deg,Toluene_X
GDHHQS3_k127_3023005_15	1229780.BN381_780008	1.881e-89	303.0	COG0693@1|root,COG3119@1|root,COG0693@2|Bacteria,COG3119@2|Bacteria,2HEWZ@201174|Actinobacteria,3UXNN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
GDHHQS3_k127_3023005_16	1333998.M2A_0798	3.532e-80	287.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,4BT4A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
GDHHQS3_k127_3023005_33	1121920.AUAU01000011_gene160	7.646e-10	68.0	2C852@1|root,32YB2@2|Bacteria,3Y55S@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
GDHHQS3_k127_3023005_22	96561.Dole_2460	2.618e-52	199.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_1	1123073.KB899241_gene3395	6.648e-253	788.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_3023005_38	794903.OPIT5_10810	5.754e-05	55.0	arCOG12117@1|root,2Z9N1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
GDHHQS3_k127_3023005_25	1120950.KB892807_gene1561	5.138e-46	182.0	COG0454@1|root,COG0456@2|Bacteria,2IM2R@201174|Actinobacteria,4DRSY@85009|Propionibacteriales	201174|Actinobacteria	K	FR47-like protein	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_3023005_13	869210.Marky_0500	4.63e-119	406.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_3023005_35	1192034.CAP_3946	3.6e-09	62.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_3023005_32	983545.Glaag_3193	2.319e-13	80.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,1RZ8A@1236|Gammaproteobacteria,466K0@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_6	46234.ANA_C11362	7.963e-163	531.0	COG0641@1|root,COG0641@2|Bacteria,1GAI2@1117|Cyanobacteria	1117|Cyanobacteria	C	Radical SAM additional 4Fe4S-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS3_k127_3023005_11	46234.ANA_C11361	6.235e-135	454.0	2EP1D@1|root,33GN8@2|Bacteria,1GCCG@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_39	2045.KR76_22115	6.098e-05	55.0	29WAJ@1|root,30HW0@2|Bacteria,2IM73@201174|Actinobacteria,4DRFT@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GDHHQS3_k127_3023005_41	1089553.Tph_c03510	0.0005232	53.0	COG2014@1|root,COG2014@2|Bacteria,1UF0B@1239|Firmicutes,25JRJ@186801|Clostridia,42I7Y@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364
GDHHQS3_k127_3023005_29	1123504.JQKD01000003_gene597	6.382e-24	120.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1-like protein	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
GDHHQS3_k127_3023005_36	935863.AWZR01000002_gene976	1.148e-05	56.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1X8GB@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
GDHHQS3_k127_3023005_12	1089550.ATTH01000001_gene1831	3.129e-129	449.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
GDHHQS3_k127_3023005_21	861299.J421_2120	1.226e-69	246.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	eaeH	GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Amidase_2,Big_1,CW_7,DUF1529,DUF928,IAT_beta,Invasin_D3,LysM
GDHHQS3_k127_3023005_40	1201288.M900_1740	0.0003438	51.0	COG0705@1|root,COG0705@2|Bacteria,1PD2F@1224|Proteobacteria,42XIJ@68525|delta/epsilon subdivisions,2MT85@213481|Bdellovibrionales,2WT8Q@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Eukaryotic integral membrane protein (DUF1751)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_3023005_7	215803.DB30_3071	1.553e-151	531.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WYNH@28221|Deltaproteobacteria,2YZIM@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3023005_27	391603.FBALC1_10962	1.693e-27	132.0	COG1361@1|root,COG2304@1|root,COG3209@1|root,COG4257@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4257@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
GDHHQS3_k127_3045076_1	1128427.KB904821_gene1764	1.306e-49	196.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1G19D@1117|Cyanobacteria,1HEGM@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_3045076_2	84531.JMTZ01000011_gene3038	7.775e-47	188.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria,1XC40@135614|Xanthomonadales	135614|Xanthomonadales	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
GDHHQS3_k127_3045076_0	1123508.JH636442_gene4006	2.141e-220	709.0	COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes	203682|Planctomycetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_3055121_1	652103.Rpdx1_3642	4.151e-55	215.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,3K57D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_3055121_2	1041522.MCOL_V209960	2.251e-05	57.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,235TD@1762|Mycobacteriaceae	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GDHHQS3_k127_3055121_0	489825.LYNGBM3L_05790	2.253e-65	235.0	COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1H9SQ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_3212144_3	1340493.JNIF01000003_gene2109	8.635e-210	673.0	COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GDHHQS3_k127_3212144_37	679197.HMPREF9336_02804	1.021e-10	74.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GDHHQS3_k127_3212144_33	396588.Tgr7_1004	4.193e-19	99.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS3_k127_3212144_19	682795.AciX8_0687	1.718e-58	215.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_3212144_22	246197.MXAN_2071	5.688e-54	204.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
GDHHQS3_k127_3212144_30	378806.STAUR_6189	8.725e-30	121.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2YVRR@29|Myxococcales	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS3_k127_3212144_2	754476.Q7A_1301	2.394e-217	701.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS3_k127_3212144_16	880073.Calab_1129	2.368e-71	249.0	COG0327@1|root,COG0327@2|Bacteria,2NR2X@2323|unclassified Bacteria	2|Bacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
GDHHQS3_k127_3212144_20	945713.IALB_1134	2.803e-58	213.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
GDHHQS3_k127_3212144_5	1304888.ATWF01000001_gene2187	8.484e-189	622.0	COG0143@1|root,COG0143@2|Bacteria,2GF31@200930|Deferribacteres	200930|Deferribacteres	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GDHHQS3_k127_3212144_21	1111069.TCCBUS3UF1_11750	1.265e-57	212.0	COG1281@1|root,COG1281@2|Bacteria,1WJ1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
GDHHQS3_k127_3212144_10	1144275.COCOR_05913	1.934e-115	393.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,42YQ0@68525|delta/epsilon subdivisions,2WTRV@28221|Deltaproteobacteria,2YUFX@29|Myxococcales	28221|Deltaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3212144_25	702450.CUW_1055	1.934e-47	180.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,3VQK7@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GDHHQS3_k127_3212144_15	698757.Pogu_0163	1.812e-72	252.0	COG0846@1|root,arCOG04248@2157|Archaea,2XQBQ@28889|Crenarchaeota	28889|Crenarchaeota	K	form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS3_k127_3212144_26	1122185.N792_09270	4.655e-46	173.0	29IJ4@1|root,313M6@2|Bacteria,1QGNE@1224|Proteobacteria,1TD6K@1236|Gammaproteobacteria,1XA86@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GDHHQS3_k127_3212144_6	292459.STH2916	7.101e-186	594.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
GDHHQS3_k127_3212144_1	330214.NIDE0577	3.741e-237	758.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
GDHHQS3_k127_3212144_24	1232410.KI421425_gene1556	6.476e-49	187.0	COG3212@1|root,COG3212@2|Bacteria,1N0D3@1224|Proteobacteria	1224|Proteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
GDHHQS3_k127_3212144_38	163908.KB235896_gene3429	3.018e-05	57.0	COG2755@1|root,COG2755@2|Bacteria,1G2MF@1117|Cyanobacteria,1HMQ4@1161|Nostocales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_3212144_32	530564.Psta_1246	2.144e-23	117.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3212144_28	926569.ANT_12000	1.406e-41	170.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_3212144_29	351627.Csac_1727	1.733e-36	143.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_3212144_18	765912.Thimo_1140	8.424e-68	243.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS3_k127_3212144_11	1192034.CAP_5305	6.261e-109	370.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_3212144_14	1183438.GKIL_2151	9.704e-84	293.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_3212144_8	1183438.GKIL_2151	2.157e-144	497.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_3212144_13	1183438.GKIL_2152	3.723e-86	301.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_3212144_9	1122176.KB903531_gene2990	2.082e-129	449.0	COG4412@1|root,COG4412@2|Bacteria,4PM4A@976|Bacteroidetes,1IWTI@117747|Sphingobacteriia	976|Bacteroidetes	UW	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36
GDHHQS3_k127_3212144_36	864702.OsccyDRAFT_1783	1.071e-12	82.0	COG1404@1|root,COG3209@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,RHS_repeat,SdrD_B
GDHHQS3_k127_3212144_34	1398491.P613_01810	8.022e-17	96.0	COG0455@1|root,COG0455@2|Bacteria,2J5K5@203691|Spirochaetes	203691|Spirochaetes	D	ATP-binding protein	ylxH-2	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
GDHHQS3_k127_3212144_4	1279009.ADICEAN_00512	5.577e-202	663.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GDHHQS3_k127_3212144_17	1449346.JQMO01000003_gene4428	3.497e-70	251.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,2M1JS@2063|Kitasatospora	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS3_k127_3212144_0	290397.Adeh_1417	3.204e-248	781.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_3212144_23	1191523.MROS_0145	4.634e-52	195.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
GDHHQS3_k127_3212144_31	240016.ABIZ01000001_gene5664	6.379e-28	129.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
GDHHQS3_k127_3212144_35	909613.UO65_6653	3.469e-14	84.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,4E4SF@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3212144_7	511051.CSE_10010	6.541e-175	558.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_3212144_27	1276756.AUEX01000014_gene2887	6.818e-45	181.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,4ABBK@80864|Comamonadaceae	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS3_k127_3212144_12	1267533.KB906733_gene2818	1.13e-103	363.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria,2JI29@204432|Acidobacteriia	204432|Acidobacteriia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS3_k127_3240637_2	1267535.KB906767_gene3855	9.581e-71	245.0	COG0364@1|root,COG0364@2|Bacteria,3Y627@57723|Acidobacteria,2JKTN@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS3_k127_3240637_1	196162.Noca_1788	9.789e-188	606.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4DTHI@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
GDHHQS3_k127_3240637_3	324602.Caur_3470	6.901e-28	132.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GDHHQS3_k127_3240637_0	196490.AUEZ01000042_gene7227	3.5e-323	1005.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_3240637_4	867903.ThesuDRAFT_01378	8.131e-16	77.0	COG1878@1|root,COG1878@2|Bacteria,1V07X@1239|Firmicutes,24EXW@186801|Clostridia,3WDKA@538999|Clostridiales incertae sedis	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS3_k127_3302480_3	1321781.HMPREF1985_01477	2.037e-17	86.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4H1YC@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS3_k127_3302480_4	1384056.N787_04530	1.579e-13	79.0	COG2104@1|root,COG2104@2|Bacteria,1NDN4@1224|Proteobacteria,1T0G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_3302480_2	436114.SYO3AOP1_0852	4.33e-91	307.0	COG2022@1|root,COG2022@2|Bacteria,2G4F7@200783|Aquificae	200783|Aquificae	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS3_k127_3302480_0	234267.Acid_5676	1.583e-232	754.0	COG0515@1|root,COG1262@1|root,COG1506@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	1.14.99.50,2.7.11.1	ko:K01990,ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	M00254	R11013	RC03323,RC03324	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1	-	-	FGE-sulfatase,Peptidase_S15,Pkinase
GDHHQS3_k127_3302480_5	1128421.JAGA01000001_gene2161	1.094e-11	67.0	COG2022@1|root,COG2022@2|Bacteria,2NQHA@2323|unclassified Bacteria	2|Bacteria	H	Thiazole biosynthesis protein ThiG	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
GDHHQS3_k127_3302480_1	234267.Acid_5676	1.178e-160	531.0	COG0515@1|root,COG1262@1|root,COG1506@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	1.14.99.50,2.7.11.1	ko:K01990,ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	M00254	R11013	RC03323,RC03324	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1	-	-	FGE-sulfatase,Peptidase_S15,Pkinase
GDHHQS3_k127_3383738_2	96561.Dole_2317	1.827e-12	76.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3383738_0	365046.Rta_09290	1.674e-49	191.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_3383738_1	861299.J421_3014	4.446e-31	125.0	2DJKR@1|root,32X86@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3383738_3	1122604.JONR01000008_gene2145	1.097e-09	59.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SGD7@1236|Gammaproteobacteria,1X8RN@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
GDHHQS3_k127_3438717_1	1382306.JNIM01000001_gene1024	1.25e-32	130.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_3438717_0	1382306.JNIM01000001_gene1023	1.796e-185	597.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_3446578_2	1444309.JAQG01000164_gene1837	7.381e-135	443.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
GDHHQS3_k127_3446578_1	1300345.LF41_1550	6.278e-142	470.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1RQ3H@1236|Gammaproteobacteria,1X3SI@135614|Xanthomonadales	135614|Xanthomonadales	T	two-component system sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_3446578_0	189753.AXAS01000020_gene1699	0.0	1660.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWQB@28211|Alphaproteobacteria,3JQWC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	MA20_07280	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_3488723_1	1121272.KB903290_gene4754	2.477e-55	197.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4D9SG@85008|Micromonosporales	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_3488723_0	68219.JNXI01000010_gene5730	1.134e-77	278.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_3488723_2	477641.MODMU_1595	1.851e-19	88.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_34895_8	1121445.ATUZ01000016_gene2481	3.413e-71	248.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_34895_16	555778.Hneap_0168	1.604e-21	108.0	COG2062@1|root,COG2062@2|Bacteria,1PKQR@1224|Proteobacteria,1TKA8@1236|Gammaproteobacteria,1X12R@135613|Chromatiales	135613|Chromatiales	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GDHHQS3_k127_34895_15	861299.J421_3996	7.613e-36	154.0	COG2954@1|root,COG5607@1|root,COG2954@2|Bacteria,COG5607@2|Bacteria,1ZTYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
GDHHQS3_k127_34895_0	321332.CYB_2082	6.586e-233	740.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GDHHQS3_k127_34895_2	1403819.BATR01000112_gene3805	3.129e-122	400.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,2ITM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GDHHQS3_k127_34895_4	338966.Ppro_0405	1.509e-107	359.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions,2WK0P@28221|Deltaproteobacteria,43T7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_34895_3	1280944.HY17_07980	2.999e-111	393.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VFV7@28211|Alphaproteobacteria,44139@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS3_k127_34895_19	690850.Desaf_0366	0.0006086	52.0	COG1595@1|root,COG1595@2|Bacteria,1NY42@1224|Proteobacteria,435XV@68525|delta/epsilon subdivisions,2X0EN@28221|Deltaproteobacteria,2MC1Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
GDHHQS3_k127_34895_11	1173027.Mic7113_0525	6.661e-57	226.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
GDHHQS3_k127_34895_5	313606.M23134_07555	1.157e-84	295.0	295M7@1|root,2ZSYM@2|Bacteria,4NNH9@976|Bacteroidetes,47UGS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_34895_18	136993.KB900626_gene1115	1.677e-11	76.0	COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,2UDT4@28211|Alphaproteobacteria,37130@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_34895_13	1538644.KO02_23380	1.732e-37	152.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS3_k127_34895_1	1379698.RBG1_1C00001G0364	2.685e-126	415.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS3_k127_34895_7	330214.NIDE2415	4.105e-77	278.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,3J0K5@40117|Nitrospirae	2|Bacteria	FP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ppx	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K07012	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000,ko02048	-	-	-	HD,Helicase_C,Ppx-GppA,Response_reg
GDHHQS3_k127_34895_6	243231.GSU1101	5.746e-80	302.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS3_k127_34895_14	316067.Geob_1987	2.388e-36	160.0	COG3746@1|root,COG3746@2|Bacteria,1N2GT@1224|Proteobacteria,42U60@68525|delta/epsilon subdivisions,2WQXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
GDHHQS3_k127_34895_9	330214.NIDE2416	5.646e-67	236.0	COG0704@1|root,COG0704@2|Bacteria,3J0M6@40117|Nitrospirae	40117|Nitrospirae	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS3_k127_34895_12	234267.Acid_5515	1.175e-43	167.0	COG1848@1|root,COG1848@2|Bacteria,3Y8JE@57723|Acidobacteria	57723|Acidobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_34895_17	1353531.AZNX01000005_gene3405	2.815e-17	83.0	2DPH3@1|root,33224@2|Bacteria,1NE43@1224|Proteobacteria,2UUE0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_34895_10	1232410.KI421421_gene3403	2.928e-58	219.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,43S2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS3_k127_3509189_0	483219.LILAB_17655	0.0	1258.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WP5J@28221|Deltaproteobacteria,2Z2XG@29|Myxococcales	28221|Deltaproteobacteria	H	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS3_k127_3509189_2	1121920.AUAU01000004_gene664	2.163e-146	475.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS3_k127_3509189_3	1121920.AUAU01000004_gene665	8.101e-100	337.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_3509189_9	95619.PM1_0230835	6.286e-33	143.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0071944	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
GDHHQS3_k127_3509189_1	1121920.AUAU01000004_gene667	9.697e-180	576.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3509189_10	396588.Tgr7_2443	1.55e-32	134.0	COG5611@1|root,COG5611@2|Bacteria,1N9JM@1224|Proteobacteria,1SYAP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3509189_12	1528098.NOVO_09370	1.037e-08	59.0	COG2002@1|root,COG2002@2|Bacteria,1NIC5@1224|Proteobacteria,2VGG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	PrlF_antitoxin
GDHHQS3_k127_3509189_8	525904.Tter_0602	1.827e-38	156.0	COG2367@1|root,COG2367@2|Bacteria,2NQ4B@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase enzyme family	-	-	3.4.16.4,3.5.2.6	ko:K07258,ko:K17836	ko00311,ko00550,ko01100,ko01130,ko01501,map00311,map00550,map01100,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase2
GDHHQS3_k127_3509189_6	1396418.BATQ01000045_gene6031	5.222e-57	207.0	COG0725@1|root,COG0725@2|Bacteria,46V5J@74201|Verrucomicrobia,2IUY6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
GDHHQS3_k127_3509189_5	278957.ABEA03000004_gene4545	2.545e-65	229.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,3K813@414999|Opitutae	414999|Opitutae	P	Molybdate ABC transporter	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
GDHHQS3_k127_3509189_7	1380355.JNIJ01000007_gene3345	5.836e-42	177.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,3JUD5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
GDHHQS3_k127_3509189_11	1123229.AUBC01000024_gene4551	2.261e-09	70.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,2U8MR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
GDHHQS3_k127_3509189_4	1121272.KB903249_gene1700	1.381e-95	332.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2GJYH@201174|Actinobacteria,4DBUI@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
GDHHQS3_k127_3510618_19	234267.Acid_5890	1.128e-40	158.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS3_k127_3510618_18	1089553.Tph_c13460	8.198e-46	182.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,42GU1@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
GDHHQS3_k127_3510618_35	323850.Shew_3626	2.601e-10	72.0	2DX8W@1|root,32V31@2|Bacteria,1R3I9@1224|Proteobacteria,1T68F@1236|Gammaproteobacteria,2QC7P@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3510618_24	926554.KI912648_gene4921	2.897e-22	108.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS3_k127_3510618_30	41431.PCC8801_0390	3.222e-18	91.0	2E4J8@1|root,32ZEA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2541
GDHHQS3_k127_3510618_34	1238182.C882_3063	1.482e-10	70.0	COG4891@1|root,COG4891@2|Bacteria,1N4U1@1224|Proteobacteria,2UGHM@28211|Alphaproteobacteria,2JUWM@204441|Rhodospirillales	204441|Rhodospirillales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_3510618_3	521045.Kole_1526	3.097e-115	389.0	COG3635@1|root,COG3635@2|Bacteria,2GBZH@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
GDHHQS3_k127_3510618_23	1120950.KB892731_gene3823	1.317e-29	128.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4DQDZ@85009|Propionibacteriales	201174|Actinobacteria	G	KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS3_k127_3510618_21	1330700.JQNC01000003_gene922	9.805e-37	149.0	COG0565@1|root,COG0565@2|Bacteria,1WJDP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GDHHQS3_k127_3510618_7	1242864.D187_000069	1.38e-86	299.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_3510618_0	439235.Dalk_0885	2.778e-199	657.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2MIDT@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Alpha amylase, catalytic	-	-	2.4.1.4,2.4.1.7	ko:K00690,ko:K05341	ko00500,map00500	-	R00803,R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_3510618_5	671143.DAMO_1541	4.88e-106	357.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
GDHHQS3_k127_3510618_4	589873.EP13_14930	3.827e-107	364.0	COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,1RQFS@1236|Gammaproteobacteria,464TB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	nanT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GDHHQS3_k127_3510618_17	330214.NIDE4204	1.282e-48	186.0	COG3769@1|root,COG3769@2|Bacteria	2|Bacteria	S	mannosylglycerate metabolic process	mpgP	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897	2.4.1.217,3.1.3.70	ko:K05947,ko:K07026	ko00051,map00051	-	R05768,R05790	RC00005,RC00017,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Hydrolase_3
GDHHQS3_k127_3510618_8	324602.Caur_0619	2.146e-78	282.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GDHHQS3_k127_3510618_14	234267.Acid_3421	2.717e-57	222.0	COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria	57723|Acidobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
GDHHQS3_k127_3510618_9	215803.DB30_6515	4.021e-76	274.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,42RQH@68525|delta/epsilon subdivisions,2WTKY@28221|Deltaproteobacteria,2YTSF@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
GDHHQS3_k127_3510618_20	861299.J421_0889	5.884e-38	157.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GDHHQS3_k127_3510618_33	1125863.JAFN01000001_gene3582	1.514e-11	76.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS3_k127_3510618_6	1234364.AMSF01000017_gene1451	2.047e-94	334.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,1RUQU@1236|Gammaproteobacteria,1X4NG@135614|Xanthomonadales	135614|Xanthomonadales	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3510618_31	446462.Amir_1210	5.504e-17	82.0	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria,4E6UQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3510618_37	379066.GAU_3657	3.86e-05	51.0	2AU93@1|root,31JWF@2|Bacteria,1ZV74@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3510618_38	481448.Minf_1004	0.000768	51.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46ZAG@74201|Verrucomicrobia,37GHV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
GDHHQS3_k127_3510618_26	1267533.KB906734_gene4322	2.148e-20	105.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GDHHQS3_k127_3510618_15	1267535.KB906767_gene4741	6.836e-57	217.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
GDHHQS3_k127_3510618_25	204669.Acid345_0150	2.201e-21	103.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria,2JJKY@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_3510618_29	1242864.D187_010180	1.447e-18	91.0	COG0848@1|root,COG0848@2|Bacteria,1Q1RQ@1224|Proteobacteria,437EZ@68525|delta/epsilon subdivisions,2X2MA@28221|Deltaproteobacteria,2Z03D@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_3510618_27	1121015.N789_01385	2.965e-20	100.0	COG1462@1|root,COG1462@2|Bacteria,1Q8KJ@1224|Proteobacteria,1RU2Q@1236|Gammaproteobacteria,1X6HV@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GDHHQS3_k127_3510618_22	1121920.AUAU01000030_gene2721	1.009e-36	159.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000030_gene2721|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3510618_12	1232410.KI421412_gene48	1.92e-61	227.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,43S2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS3_k127_3510618_28	1121439.dsat_1861	2.363e-19	103.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MBU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS3_k127_3510618_2	502025.Hoch_3781	1.469e-118	404.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_3510618_13	316067.Geob_1869	3.036e-58	233.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
GDHHQS3_k127_3510618_11	351607.Acel_0416	1.575e-61	222.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4ERZQ@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS3_k127_3510618_1	717606.PaecuDRAFT_4483	2.378e-133	438.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_3510618_16	1278073.MYSTI_05892	8.544e-49	196.0	COG1089@1|root,COG1089@2|Bacteria,1QXV3@1224|Proteobacteria,4347Z@68525|delta/epsilon subdivisions,2X7I2@28221|Deltaproteobacteria,2YXC2@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_3510618_10	72658.Bostr.7867s1183.1.p	1.566e-64	246.0	COG0451@1|root,KOG1502@2759|Eukaryota,37JYY@33090|Viridiplantae,3G71H@35493|Streptophyta,3HP0I@3699|Brassicales	35493|Streptophyta	V	NmrA-like family	-	-	1.1.1.354	ko:K15891	ko00900,ko00909,ko01130,map00900,map00909,map01130	-	R10412	RC00649	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS3_k127_3510618_36	70448.Q015U0	2.644e-06	60.0	COG0170@1|root,KOG4453@2759|Eukaryota,37MAD@33090|Viridiplantae,34HWV@3041|Chlorophyta	3041|Chlorophyta	I	Phytol kinase	-	-	2.7.1.182,2.7.1.216	ko:K15892,ko:K18678	ko00900,ko01130,map00900,map01130	-	R09849,R10659	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_3510618_32	4577.GRMZM2G166383_P01	3.343e-15	89.0	COG1836@1|root,2QU2J@2759|Eukaryota,37MEJ@33090|Viridiplantae,3GBQ6@35493|Streptophyta,3KMAF@4447|Liliopsida,3I9R0@38820|Poales	35493|Streptophyta	S	Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS3_k127_3609777_1	913325.N799_10770	3.564e-30	127.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3609777_0	1121878.AUGL01000020_gene3037	1.118e-76	265.0	COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,1S0XC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS3_k127_3642971_38	483219.LILAB_33565	3.906e-09	70.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria,2YXF4@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS3_k127_3642971_3	639030.JHVA01000001_gene2643	7.418e-164	530.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS3_k127_3642971_32	794903.OPIT5_14435	3.286e-17	88.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS3_k127_3642971_31	981384.AEYW01000013_gene649	4.266e-19	99.0	COG0671@1|root,COG0671@2|Bacteria,1RF6B@1224|Proteobacteria,2U8U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS3_k127_3642971_4	1121087.AUCK01000005_gene701	1.558e-163	540.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS3_k127_3642971_1	234267.Acid_7303	4.288e-212	677.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS3_k127_3642971_8	1442599.JAAN01000010_gene242	1.443e-113	388.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1X2YF@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS3_k127_3642971_13	102129.Lepto7375DRAFT_1625	1.655e-81	290.0	COG0391@1|root,COG0391@2|Bacteria,1G0R0@1117|Cyanobacteria,1H815@1150|Oscillatoriales	1117|Cyanobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GDHHQS3_k127_3642971_10	243231.GSU0099	8.635e-92	314.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
GDHHQS3_k127_3642971_20	338966.Ppro_2941	5.206e-58	207.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GDHHQS3_k127_3642971_37	525146.Ddes_2104	3.183e-09	64.0	COG4393@1|root,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2WQ0C@28221|Deltaproteobacteria,2MBVE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
GDHHQS3_k127_3642971_27	469383.Cwoe_4930	3.238e-32	145.0	COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,2IA4H@201174|Actinobacteria,4CP5Q@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
GDHHQS3_k127_3642971_33	439235.Dalk_1453	5.545e-12	79.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3642971_11	671143.DAMO_2491	1.493e-90	306.0	COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria	2|Bacteria	IQ	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_3642971_40	1229487.AMYW01000007_gene3197	0.0009263	49.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3642971_39	1111728.ATYS01000050_gene3561	0.0002804	50.0	2DSWF@1|root,33HPF@2|Bacteria,1NMM8@1224|Proteobacteria,1SIHM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3642971_21	1144275.COCOR_04390	3.207e-51	190.0	COG0398@1|root,COG0398@2|Bacteria,1N99S@1224|Proteobacteria	1224|Proteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_3642971_28	234267.Acid_2001	6.431e-32	132.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
GDHHQS3_k127_3642971_34	653733.Selin_0858	6.152e-12	76.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_3642971_19	573370.DMR_08160	1.19e-58	228.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42RQD@68525|delta/epsilon subdivisions,2WNSR@28221|Deltaproteobacteria,2MG5H@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_3642971_15	204669.Acid345_4023	1.092e-72	268.0	COG0577@1|root,COG0577@2|Bacteria,3Y5DA@57723|Acidobacteria,2JNJ8@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
GDHHQS3_k127_3642971_17	204669.Acid345_4024	5.734e-62	221.0	COG1309@1|root,COG1309@2|Bacteria,3Y5TS@57723|Acidobacteria,2JK51@204432|Acidobacteriia	204432|Acidobacteriia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GDHHQS3_k127_3642971_16	1379698.RBG1_1C00001G0518	6.443e-71	267.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_3642971_26	1121405.dsmv_1056	3.627e-34	138.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria,2MJY8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3392	Flavoprotein
GDHHQS3_k127_3642971_2	1242864.D187_000308	2.632e-205	680.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS3_k127_3642971_9	671143.DAMO_2568	1.181e-99	363.0	COG1432@1|root,COG1432@2|Bacteria,2NQWI@2323|unclassified Bacteria	2|Bacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GDHHQS3_k127_3642971_5	1278073.MYSTI_00520	8.807e-145	470.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_3642971_7	926560.KE387023_gene3153	1.519e-127	415.0	COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS3_k127_3642971_22	401053.AciPR4_1033	6.121e-47	185.0	COG0400@1|root,COG0400@2|Bacteria,3Y7KS@57723|Acidobacteria,2JMRI@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS3_k127_3642971_24	1183438.GKIL_2917	2.599e-36	161.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_3642971_0	1519464.HY22_03790	3.116e-215	674.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,GARS_A,GARS_C,GARS_N
GDHHQS3_k127_3642971_29	1121920.AUAU01000030_gene2713	6.946e-31	126.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3642971_6	234267.Acid_1309	5.947e-133	434.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_3642971_14	645465.ACUR01000248_gene5840	9.006e-78	270.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
GDHHQS3_k127_3642971_36	318996.AXAZ01000074_gene2177	1.653e-09	71.0	2A8S6@1|root,30XUV@2|Bacteria,1NPUS@1224|Proteobacteria,2UNY7@28211|Alphaproteobacteria,3K3IV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3642971_23	314271.RB2654_20228	1.803e-39	161.0	2E3K6@1|root,32YIF@2|Bacteria,1N3IM@1224|Proteobacteria,2TXZE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
GDHHQS3_k127_3642971_30	314271.RB2654_06554	2.403e-21	104.0	COG1442@1|root,COG1442@2|Bacteria,1MXIY@1224|Proteobacteria,2U52Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
GDHHQS3_k127_3642971_25	1150600.ADIARSV_2812	1.61e-35	145.0	COG1216@1|root,COG1216@2|Bacteria,4NMXY@976|Bacteroidetes,1IRVI@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3642971_35	926566.Terro_1919	1.339e-10	74.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria,2JJVA@204432|Acidobacteriia	204432|Acidobacteriia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS3_k127_3642971_18	370438.PTH_2721	1.142e-58	223.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS3_k127_3642971_12	264732.Moth_0263	9.931e-85	288.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS3_k127_3705277_15	1097668.BYI23_A006890	1.134e-45	187.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,1K0FS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_3705277_9	862908.BMS_2857	5.316e-88	319.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,43E4Q@68525|delta/epsilon subdivisions,2MTP3@213481|Bdellovibrionales,2X7E4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	CO dehydrogenase flavoprotein C-terminal domain	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GDHHQS3_k127_3705277_12	222534.KB893694_gene90	1.34e-72	255.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4ERSB@85013|Frankiales	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
GDHHQS3_k127_3705277_6	675635.Psed_1758	7.506e-124	435.0	COG0044@1|root,COG0044@2|Bacteria,2IAM1@201174|Actinobacteria,4DXSN@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GDHHQS3_k127_3705277_23	1396858.Q666_01415	1.623e-30	141.0	COG3195@1|root,COG3195@2|Bacteria,1RIGR@1224|Proteobacteria,1S6QX@1236|Gammaproteobacteria,467QT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	OHCU decarboxylase	uraD	-	4.1.1.97	ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
GDHHQS3_k127_3705277_21	861299.J421_2144	3.713e-36	140.0	COG2351@1|root,COG2351@2|Bacteria	2|Bacteria	MU	hydroxyisourate hydrolase activity	uraH	GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	3.5.2.17,4.1.1.97	ko:K07127,ko:K13485	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601,R06604	RC01551,RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
GDHHQS3_k127_3705277_7	626418.bglu_1g13140	2.846e-115	384.0	COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,2VKRI@28216|Betaproteobacteria,1K1GK@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase
GDHHQS3_k127_3705277_20	398578.Daci_5077	2.404e-36	155.0	COG3194@1|root,COG3194@2|Bacteria,1RH5G@1224|Proteobacteria,2VT31@28216|Betaproteobacteria,4AF02@80864|Comamonadaceae	28216|Betaproteobacteria	F	Ureidoglycolate lyase	allA	-	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	-	Ureidogly_lyase
GDHHQS3_k127_3705277_19	452637.Oter_0579	2.209e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,46WC7@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3705277_24	382464.ABSI01000020_gene326	1.339e-24	118.0	COG5660@1|root,COG5660@2|Bacteria,46W99@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
GDHHQS3_k127_3705277_22	382464.ABSI01000020_gene325	4.635e-33	147.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_3705277_13	1123277.KB893172_gene531	1.247e-53	199.0	COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_3705277_17	85643.Tmz1t_1810	3.299e-39	162.0	COG0477@1|root,COG2814@2|Bacteria,1RCII@1224|Proteobacteria	1224|Proteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3705277_14	1144275.COCOR_02951	6.471e-53	212.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
GDHHQS3_k127_3705277_4	1089550.ATTH01000001_gene738	4.473e-128	461.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_3705277_1	1304883.KI912532_gene2256	1.168e-187	597.0	COG1055@1|root,COG1055@2|Bacteria,1PUZK@1224|Proteobacteria,2VKEF@28216|Betaproteobacteria,2KYH0@206389|Rhodocyclales	206389|Rhodocyclales	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705277_2	1304883.KI912532_gene2256	7.354e-186	591.0	COG1055@1|root,COG1055@2|Bacteria,1PUZK@1224|Proteobacteria,2VKEF@28216|Betaproteobacteria,2KYH0@206389|Rhodocyclales	206389|Rhodocyclales	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705277_3	1266909.AUAG01000013_gene697	9.165e-134	442.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0464 ATPases of the AAA class	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS3_k127_3705277_18	1123242.JH636435_gene2917	1.584e-38	164.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_3705277_0	290397.Adeh_3184	0.0	3660.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS3_k127_3705277_10	1379270.AUXF01000003_gene3809	2.332e-86	300.0	COG0730@1|root,COG0730@2|Bacteria,1ZUET@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705277_8	861299.J421_1211	3.023e-96	344.0	2CAE5@1|root,313QD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705277_5	861299.J421_1210	5.127e-124	414.0	28JRE@1|root,2Z9H3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3705277_27	1242864.D187_002208	5.513e-07	51.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_3705277_16	1120950.KB892799_gene2145	8.621e-41	170.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS3_k127_3705277_28	1184609.KILIM_062_00090	0.0001164	46.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4F6YV@85018|Dermatophilaceae	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_3705277_11	1313172.YM304_24680	8.446e-77	275.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS3_k127_3731750_29	1232410.KI421424_gene1719	4.155e-43	178.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SED@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS3_k127_3731750_30	1122622.ATWJ01000001_gene2530	7.813e-39	164.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4FE9M@85021|Intrasporangiaceae	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GDHHQS3_k127_3731750_14	264732.Moth_0915	3.11e-93	318.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GDHHQS3_k127_3731750_15	498761.HM1_2174	9.41e-89	308.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS3_k127_3731750_51	1121918.ARWE01000001_gene2061	6.891e-07	57.0	COG2018@1|root,COG2018@2|Bacteria,1N5TV@1224|Proteobacteria,42UGD@68525|delta/epsilon subdivisions,2WQXP@28221|Deltaproteobacteria,43SPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GDHHQS3_k127_3731750_17	204669.Acid345_3335	1.26e-79	292.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_3731750_22	935863.AWZR01000007_gene170	3.71e-63	233.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1X42C@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GDHHQS3_k127_3731750_43	390989.JOEG01000022_gene2304	7.37e-13	81.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DC6X@85008|Micromonosporales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
GDHHQS3_k127_3731750_39	1054213.HMPREF9946_02877	1.258e-17	96.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
GDHHQS3_k127_3731750_20	370438.PTH_2352	2.685e-69	270.0	28JGA@1|root,2Z9A3@2|Bacteria,1VJ9Q@1239|Firmicutes,24SUJ@186801|Clostridia,264JT@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3731750_5	767817.Desgi_2846	2.147e-207	685.0	COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia,261E8@186807|Peptococcaceae	186801|Clostridia	P	NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_3731750_0	485916.Dtox_0939	2.079e-267	845.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
GDHHQS3_k127_3731750_24	1304885.AUEY01000023_gene2690	1.701e-57	217.0	COG0845@1|root,COG0845@2|Bacteria,1QZQZ@1224|Proteobacteria,42STU@68525|delta/epsilon subdivisions,2WPYM@28221|Deltaproteobacteria,2MNJA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS3_k127_3731750_40	760192.Halhy_0669	4.598e-16	93.0	COG1538@1|root,COG1538@2|Bacteria,4NI8J@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_3731750_44	1415780.JPOG01000001_gene3345	5.708e-12	79.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GDHHQS3_k127_3731750_34	118161.KB235919_gene6304	1.553e-34	155.0	COG0454@1|root,COG0456@2|Bacteria,1G56V@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3731750_18	483219.LILAB_14550	3.474e-79	298.0	COG4403@1|root,COG4403@2|Bacteria,1R8VP@1224|Proteobacteria,432AY@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	Domain of unknown function (DUF4135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
GDHHQS3_k127_3731750_46	913325.N799_06160	5.372e-09	69.0	COG1011@1|root,COG1011@2|Bacteria,1RIVV@1224|Proteobacteria,1SFD7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase (HAD superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_3731750_23	1125863.JAFN01000001_gene26	1.569e-59	222.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
GDHHQS3_k127_3731750_35	1121920.AUAU01000023_gene2415	8.746e-34	145.0	COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,cNMP_binding
GDHHQS3_k127_3731750_42	1380394.JADL01000003_gene4840	3.462e-13	79.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,2UH20@28211|Alphaproteobacteria,2JTY1@204441|Rhodospirillales	204441|Rhodospirillales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS3_k127_3731750_19	756272.Plabr_3400	1.158e-72	267.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
GDHHQS3_k127_3731750_6	1121335.Clst_0632	1.084e-188	606.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WGX1@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_3731750_37	28444.JODQ01000005_gene1475	3.769e-26	126.0	COG1361@1|root,COG4625@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria,4EKYK@85012|Streptosporangiales	201174|Actinobacteria	M	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
GDHHQS3_k127_3731750_8	1304872.JAGC01000003_gene2864	1.101e-162	547.0	COG3866@1|root,COG3866@2|Bacteria,1RFAV@1224|Proteobacteria	1224|Proteobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GDHHQS3_k127_3731750_13	197221.22295624	3.168e-106	358.0	COG0124@1|root,COG0124@2|Bacteria,1G066@1117|Cyanobacteria	1117|Cyanobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS3_k127_3731750_27	868864.Dester_0907	3.595e-49	182.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS3_k127_3731750_33	1121918.ARWE01000001_gene3596	5.736e-35	139.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42WIA@68525|delta/epsilon subdivisions,2WS9S@28221|Deltaproteobacteria,43VMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
GDHHQS3_k127_3731750_12	1122919.KB905557_gene1201	1.666e-108	364.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,26QTH@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS3_k127_3731750_10	452637.Oter_0309	1.153e-149	500.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,3K76N@414999|Opitutae	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_3731750_21	1379281.AVAG01000090_gene309	1.454e-64	233.0	COG0398@1|root,COG0398@2|Bacteria,1Q62Z@1224|Proteobacteria,43ECR@68525|delta/epsilon subdivisions,2X24U@28221|Deltaproteobacteria,2M7XB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_3731750_38	1267535.KB906767_gene1199	4.18e-23	106.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	carQ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GDHHQS3_k127_3731750_9	452637.Oter_0301	4.169e-153	494.0	COG0500@1|root,COG2226@2|Bacteria,46TWV@74201|Verrucomicrobia	2|Bacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS3_k127_3731750_49	448385.sce5620	1.49e-07	59.0	COG0306@1|root,COG0306@2|Bacteria,1QCP3@1224|Proteobacteria	1224|Proteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS3_k127_3731750_11	1267535.KB906767_gene1428	4.086e-128	417.0	COG0535@1|root,COG0535@2|Bacteria,3Y79N@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641
GDHHQS3_k127_3731750_1	697282.Mettu_0613	9.974e-267	829.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XE1B@135618|Methylococcales	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
GDHHQS3_k127_3731750_2	697282.Mettu_0614	1.753e-216	677.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,1RY8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
GDHHQS3_k127_3731750_48	1250278.JQNQ01000001_gene3304	1.342e-07	63.0	2DC06@1|root,2ZC62@2|Bacteria,4P21F@976|Bacteroidetes,1I7VQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_29
GDHHQS3_k127_3731750_26	1131269.AQVV01000001_gene1352	3.173e-52	201.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30,GT9	-	Glyco_transf_9
GDHHQS3_k127_3731750_32	1382304.JNIL01000001_gene2452	1.811e-35	151.0	COG3356@1|root,COG3356@2|Bacteria,1V0SP@1239|Firmicutes,4IV3K@91061|Bacilli	91061|Bacilli	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3731750_16	1382306.JNIM01000001_gene623	1.015e-85	300.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_3731750_31	306281.AJLK01000134_gene1542	1.361e-37	153.0	COG1215@1|root,COG1215@2|Bacteria,1GPY1@1117|Cyanobacteria,1JMSI@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_3731750_45	65093.PCC7418_0080	1.423e-09	69.0	COG0697@1|root,COG0697@2|Bacteria,1G24W@1117|Cyanobacteria	1117|Cyanobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3731750_7	443143.GM18_0801	1.417e-184	597.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_3731750_28	1282876.BAOK01000001_gene2447	4.697e-49	199.0	COG2843@1|root,COG2843@2|Bacteria,1PH1V@1224|Proteobacteria,2VENS@28211|Alphaproteobacteria,4BT2N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS3_k127_3731750_47	1121448.DGI_0359	1.234e-07	63.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2MBG2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
GDHHQS3_k127_3731750_41	502025.Hoch_4871	2.188e-13	81.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS3_k127_3731750_25	1237149.C900_02048	9.697e-56	207.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3731750_3	234267.Acid_1826	2.144e-214	687.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria	57723|Acidobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
GDHHQS3_k127_3731750_50	641147.HMPREF9021_02064	4.701e-07	62.0	COG1716@1|root,COG1716@2|Bacteria,1PUHS@1224|Proteobacteria,2WAU3@28216|Betaproteobacteria,2KQST@206351|Neisseriales	206351|Neisseriales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
GDHHQS3_k127_3731750_4	391625.PPSIR1_19419	1.009e-211	669.0	COG0659@1|root,COG0659@2|Bacteria,1MXA7@1224|Proteobacteria,42ZHY@68525|delta/epsilon subdivisions,2WV08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
GDHHQS3_k127_3759438_38	663278.Ethha_1635	9.751e-40	155.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS3_k127_3759438_0	1125863.JAFN01000001_gene2270	0.0	1112.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS3_k127_3759438_41	1304888.ATWF01000001_gene1677	2.232e-37	152.0	COG0739@1|root,COG0739@2|Bacteria,2GF3Z@200930|Deferribacteres	200930|Deferribacteres	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_3759438_6	518766.Rmar_1523	7.97e-148	490.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_3759438_8	1121939.L861_11860	1.664e-129	442.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XHH5@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
GDHHQS3_k127_3759438_39	391625.PPSIR1_14870	3.163e-39	167.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,2YVD7@29|Myxococcales	28221|Deltaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	DHFR_1
GDHHQS3_k127_3759438_50	629773.AORY01000001_gene2231	4.119e-15	88.0	COG2940@1|root,COG2940@2|Bacteria,1Q9DE@1224|Proteobacteria,2VDKT@28211|Alphaproteobacteria,2K32C@204457|Sphingomonadales	204457|Sphingomonadales	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GDHHQS3_k127_3759438_30	903818.KI912269_gene367	7.117e-60	214.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GDHHQS3_k127_3759438_37	452637.Oter_0011	2.164e-42	168.0	COG1512@1|root,COG1512@2|Bacteria,46T36@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GDHHQS3_k127_3759438_5	290397.Adeh_3164	6.044e-153	497.0	COG0520@1|root,COG0520@2|Bacteria,1Q61V@1224|Proteobacteria,42Y6K@68525|delta/epsilon subdivisions,2WTM3@28221|Deltaproteobacteria,2YV12@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_3759438_16	909613.UO65_1777	1.93e-82	301.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4DYC6@85010|Pseudonocardiales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GDHHQS3_k127_3759438_7	279714.FuraDRAFT_2520	1.553e-143	474.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3759438_47	344747.PM8797T_11576	2.283e-24	105.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_3759438_31	330214.NIDE2086	1.573e-59	239.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS3_k127_3759438_51	247490.KSU1_D0161	1.363e-13	85.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
GDHHQS3_k127_3759438_32	1298880.AUEV01000001_gene5342	1.125e-58	228.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class v	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_3759438_19	1278073.MYSTI_05138	2.921e-77	282.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,42M1Z@68525|delta/epsilon subdivisions,2WJYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
GDHHQS3_k127_3759438_4	661478.OP10G_0994	7.896e-155	504.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_3759438_52	262724.TT_C0899	3.451e-13	80.0	COG0697@1|root,COG0697@2|Bacteria,1WI4X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3759438_48	1382356.JQMP01000003_gene1698	1.795e-19	105.0	COG1680@1|root,COG1680@2|Bacteria,2GAJ8@200795|Chloroflexi,27YVH@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_3759438_45	926566.Terro_4177	8.005e-28	120.0	29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria,2JMXT@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_3759438_29	1047013.AQSP01000111_gene1662	2.026e-61	235.0	COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_3759438_10	292459.STH725	7.536e-122	408.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_3759438_9	448385.sce2299	2.925e-128	426.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales	28221|Deltaproteobacteria	H	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_3759438_24	1191523.MROS_2717	1.516e-66	237.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_3759438_12	278963.ATWD01000001_gene4378	1.215e-97	330.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria,2JIUS@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS3_k127_3759438_18	1384054.N790_03180	2.309e-81	282.0	COG0154@1|root,COG3391@1|root,COG0154@2|Bacteria,COG3391@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gatAX	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,Lipocalin_5
GDHHQS3_k127_3759438_40	1192034.CAP_3161	1.044e-37	148.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,2YVDZ@29|Myxococcales	28221|Deltaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_3759438_35	357809.Cphy_0140	2.705e-48	179.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,21ZBC@1506553|Lachnoclostridium	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_3759438_26	324057.Pjdr2_2335	9.149e-63	226.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_3759438_3	349124.Hhal_0048	1.726e-155	507.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1WVXY@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_3759438_44	909663.KI867150_gene1362	7.919e-32	141.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3759438_33	765910.MARPU_04040	5.565e-58	224.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1WVXB@135613|Chromatiales	135613|Chromatiales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GDHHQS3_k127_3759438_1	1382359.JIAL01000001_gene2740	8.657e-275	878.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_3759438_17	644282.Deba_2109	4.832e-82	302.0	COG4775@1|root,COG5616@1|root,COG4775@2|Bacteria,COG5616@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_3759438_54	338966.Ppro_3018	1.309e-07	60.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,43SMD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
GDHHQS3_k127_3759438_21	1123368.AUIS01000001_gene2046	4.001e-73	258.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,2NCTI@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GDHHQS3_k127_3759438_36	240015.ACP_2637	2.673e-47	186.0	COG0764@1|root,COG0764@2|Bacteria,3Y7I3@57723|Acidobacteria,2JP4P@204432|Acidobacteriia	204432|Acidobacteriia	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GDHHQS3_k127_3759438_23	913325.N799_13760	7.897e-70	254.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1X4NK@135614|Xanthomonadales	135614|Xanthomonadales	I	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GDHHQS3_k127_3759438_28	1340493.JNIF01000003_gene3598	5.435e-62	226.0	COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GDHHQS3_k127_3759438_11	1499967.BAYZ01000155_gene651	1.344e-109	362.0	COG0005@1|root,COG0005@2|Bacteria,2NNYQ@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
GDHHQS3_k127_3759438_20	648996.Theam_1712	1.367e-74	259.0	COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae	200783|Aquificae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS3_k127_3759438_25	643562.Daes_1834	5.278e-66	231.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2M7VK@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS3_k127_3759438_53	1150474.JQJI01000001_gene1799	3.152e-09	68.0	COG1254@1|root,COG1254@2|Bacteria,2GDJV@200918|Thermotogae	200918|Thermotogae	C	PFAM acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS3_k127_3759438_27	234267.Acid_7098	2.331e-62	218.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GDHHQS3_k127_3759438_15	1120792.JAFV01000001_gene3127	2.052e-83	294.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,36ZVF@31993|Methylocystaceae	28211|Alphaproteobacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS3_k127_3759438_55	1210884.HG799475_gene15275	0.000137	55.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	colA	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	F5_F8_type_C,Glyco_hydro_cc,PKD,PPC,Peptidase_M9,Peptidase_M9_N
GDHHQS3_k127_3759438_13	1267535.KB906767_gene1017	2.267e-92	325.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_3759438_49	903818.KI912269_gene405	3.33e-19	102.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS3_k127_3759438_42	1123284.KB899044_gene679	3.104e-35	147.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,26NWK@186821|Sporolactobacillaceae	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS3_k127_3759438_22	1121403.AUCV01000017_gene4438	1.074e-71	264.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2MIPA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GDHHQS3_k127_3759438_34	1123242.JH636436_gene123	1.323e-50	192.0	COG0631@1|root,COG0631@2|Bacteria,2IZVG@203682|Planctomycetes	203682|Planctomycetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_3759438_2	1125863.JAFN01000001_gene1801	1.942e-192	614.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
GDHHQS3_k127_3759438_43	1187851.A33M_3201	1.524e-32	132.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3759438_14	316057.RPD_1535	2.282e-89	301.0	COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
GDHHQS3_k127_3820446_12	1120936.KB907223_gene2519	1.299e-41	160.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4EG79@85012|Streptosporangiales	201174|Actinobacteria	L	Methylpurine-DNA glycosylase (MPG)	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS3_k127_3820446_5	266117.Rxyl_3113	1.6e-82	288.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CU6C@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_3820446_10	1156937.MFUM_1040014	5.835e-43	167.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia,37GH2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS3_k127_3820446_13	945713.IALB_2247	5.775e-38	165.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS3_k127_3820446_6	237368.SCABRO_00310	3.291e-78	282.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GDHHQS3_k127_3820446_11	649638.Trad_1694	6.006e-43	170.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_3820446_2	1304284.L21TH_2085	4.173e-99	344.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
GDHHQS3_k127_3820446_1	880073.Calab_0813	5.058e-122	426.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
GDHHQS3_k127_3820446_9	383372.Rcas_3070	2.702e-52	200.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS3_k127_3820446_16	1278073.MYSTI_05190	1.876e-23	108.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YVKS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3820446_7	1121920.AUAU01000001_gene2198	8.583e-64	248.0	COG0515@1|root,COG0515@2|Bacteria,3Y7IX@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HAMP,Pkinase
GDHHQS3_k127_3820446_15	861299.J421_4438	2.367e-30	131.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GDHHQS3_k127_3820446_8	399795.CtesDRAFT_PD2769	1.366e-54	205.0	COG1541@1|root,COG1541@2|Bacteria,1QZDY@1224|Proteobacteria,2VIX3@28216|Betaproteobacteria,4ABQT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Acyl-protein synthetase, LuxE	-	-	6.2.1.19	ko:K06046	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	LuxE
GDHHQS3_k127_3820446_18	565045.NOR51B_948	2.676e-11	74.0	COG3637@1|root,COG3637@2|Bacteria,1R0YP@1224|Proteobacteria,1T4RY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3820446_19	337191.KTR9_3473	1.432e-07	59.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS3_k127_3820446_17	351016.RAZWK3B_01545	2.822e-17	94.0	COG1012@1|root,COG1012@2|Bacteria,1R656@1224|Proteobacteria,2TVT5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
GDHHQS3_k127_3820446_14	639030.JHVA01000001_gene1114	2.338e-32	138.0	2DKZK@1|root,310GY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
GDHHQS3_k127_3820446_0	391625.PPSIR1_40340	3.493e-147	505.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YTZ2@29|Myxococcales	28221|Deltaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_3820446_4	439235.Dalk_0190	7.016e-83	294.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS3_k127_3820446_20	1107311.Q767_06220	3.841e-07	61.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia,2NW4R@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin	txn	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
GDHHQS3_k127_3845217_1	926550.CLDAP_16210	1.165e-71	247.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS3_k127_3845217_2	1123368.AUIS01000003_gene1694	1.58e-66	240.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,2NCPK@225057|Acidithiobacillales	225057|Acidithiobacillales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_3845217_0	204669.Acid345_0620	1.469e-75	264.0	COG1533@1|root,COG1533@2|Bacteria,3Y2S5@57723|Acidobacteria,2JIC8@204432|Acidobacteriia	204432|Acidobacteriia	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_3864523_1	933262.AXAM01000024_gene727	1.91e-31	130.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,42WUI@68525|delta/epsilon subdivisions,2WT5M@28221|Deltaproteobacteria,2MNKV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3864523_2	270374.MELB17_14416	3.664e-19	89.0	COG4118@1|root,COG4118@2|Bacteria,1NAEH@1224|Proteobacteria,1SS0R@1236|Gammaproteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_3864523_0	502025.Hoch_1577	3.145e-103	361.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_3953097_0	1297742.A176_05069	1.612e-209	659.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
GDHHQS3_k127_3953097_5	582515.KR51_00002240	3.749e-90	304.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
GDHHQS3_k127_3953097_4	716928.AJQT01000101_gene310	3.272e-101	346.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,4BM3R@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
GDHHQS3_k127_3953097_8	357808.RoseRS_3311	3.706e-28	121.0	COG1896@1|root,COG1896@2|Bacteria,2G72G@200795|Chloroflexi,3778D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
GDHHQS3_k127_3953097_10	1200792.AKYF01000017_gene5646	1.838e-24	109.0	COG3339@1|root,COG3339@2|Bacteria,1V6NW@1239|Firmicutes,4HJQR@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS3_k127_3953097_7	316274.Haur_3694	3.697e-65	227.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,3777D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS3_k127_3953097_2	1089550.ATTH01000001_gene1237	8.657e-136	442.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS3_k127_3953097_1	1122223.KB890687_gene2974	2.745e-174	561.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
GDHHQS3_k127_3953097_3	237368.SCABRO_00906	2.562e-101	355.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_3953097_6	1379698.RBG1_1C00001G0711	1.381e-69	267.0	COG0612@1|root,COG0612@2|Bacteria,2NQHV@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_3953097_9	1267533.KB906734_gene3908	8.708e-26	108.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria	57723|Acidobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_3972285_0	582515.KR51_00029290	8.822e-77	276.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1FY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
GDHHQS3_k127_3972285_1	65497.JODV01000020_gene2002	1.056e-26	127.0	COG0127@1|root,COG0127@2|Bacteria,2IT21@201174|Actinobacteria	201174|Actinobacteria	F	non-canonical purine NTP pyrophosphatase, RdgB HAM1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS3_k127_3987031_29	1047013.AQSP01000123_gene1523	2.619e-38	165.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_3987031_23	1123242.JH636435_gene833	1.598e-67	261.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_3987031_15	1047013.AQSP01000131_gene1840	4.674e-83	309.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS3_k127_3987031_17	1047013.AQSP01000131_gene1840	2.394e-79	301.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS3_k127_3987031_35	215803.DB30_8469	1.107e-28	134.0	COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_16	1123242.JH636434_gene4961	1.919e-81	301.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_3987031_40	1047013.AQSP01000100_gene601	1.779e-14	85.0	COG0457@1|root,COG0457@2|Bacteria	1047013.AQSP01000100_gene601|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_14	1047013.AQSP01000123_gene1531	4.384e-96	348.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS3_k127_3987031_9	767817.Desgi_4028	5.485e-117	391.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_3987031_1	1232410.KI421428_gene1211	7.115e-207	659.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43RZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Aminoacyl-tRNA editing domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GDHHQS3_k127_3987031_41	215803.DB30_0794	2.091e-14	88.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2YXRH@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
GDHHQS3_k127_3987031_12	998674.ATTE01000001_gene3216	2.462e-102	342.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RY2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS3_k127_3987031_43	1192034.CAP_7377	7.804e-11	75.0	COG4796@1|root,COG4796@2|Bacteria,1QX5J@1224|Proteobacteria,4310N@68525|delta/epsilon subdivisions,2WWI7@28221|Deltaproteobacteria,2YVID@29|Myxococcales	28221|Deltaproteobacteria	U	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_47	1121946.AUAX01000027_gene7929	0.0009913	49.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_3987031_34	1313301.AUGC01000014_gene2455	2.447e-32	136.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3987031_25	1242864.D187_002766	1.06e-52	210.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
GDHHQS3_k127_3987031_21	425104.Ssed_3637	1.324e-68	255.0	COG3591@1|root,COG3591@2|Bacteria,1RFR4@1224|Proteobacteria	1224|Proteobacteria	EO	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
GDHHQS3_k127_3987031_37	875328.JDM601_4096	7.155e-24	116.0	COG1487@1|root,COG1487@2|Bacteria,2IP2H@201174|Actinobacteria,23AFN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3987031_18	68219.JNXI01000002_gene3959	7.835e-79	273.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_33	518766.Rmar_1411	2.089e-33	138.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1FJCH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS3_k127_3987031_32	1128421.JAGA01000003_gene3570	3.101e-34	140.0	COG2386@1|root,COG2386@2|Bacteria,2NPHG@2323|unclassified Bacteria	2|Bacteria	O	CcmB protein	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
GDHHQS3_k127_3987031_27	555088.DealDRAFT_1473	6.198e-52	192.0	COG0755@1|root,COG0755@2|Bacteria,1V4A6@1239|Firmicutes,24IWH@186801|Clostridia	186801|Clostridia	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS3_k127_3987031_38	1392502.JNIO01000002_gene380	1.036e-20	98.0	COG2332@1|root,COG2332@2|Bacteria,1VJ83@1239|Firmicutes,4H5PC@909932|Negativicutes	909932|Negativicutes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
GDHHQS3_k127_3987031_4	324602.Caur_0938	9.737e-131	450.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,375AP@32061|Chloroflexia	32061|Chloroflexia	O	PFAM cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS3_k127_3987031_5	243231.GSU2547	5.732e-128	451.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,43T6Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS3_k127_3987031_19	1121468.AUBR01000036_gene1298	7.812e-76	265.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42G77@68295|Thermoanaerobacterales	186801|Clostridia	D	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_3987031_24	1297742.A176_03238	4.31e-60	230.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales	28221|Deltaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
GDHHQS3_k127_3987031_22	1121920.AUAU01000004_gene900	1.486e-67	250.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase A domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,Response_reg
GDHHQS3_k127_3987031_44	1194972.MVAC_19503	1.718e-07	64.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
GDHHQS3_k127_3987031_26	204669.Acid345_0214	1.229e-52	209.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
GDHHQS3_k127_3987031_2	204669.Acid345_0212	3.135e-165	536.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
GDHHQS3_k127_3987031_45	240015.ACP_2634	4.366e-07	63.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria,2JJMD@204432|Acidobacteriia	204432|Acidobacteriia	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_31	1121406.JAEX01000005_gene3086	9.851e-36	156.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2M99K@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GDHHQS3_k127_3987031_3	1123371.ATXH01000004_gene1740	1.479e-134	441.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS3_k127_3987031_36	42256.RradSPS_2997	5.74e-26	115.0	COG5573@1|root,COG5573@2|Bacteria,2GY55@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3987031_42	42256.RradSPS_2998	2.695e-12	69.0	2EJAF@1|root,33D1M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_39	626887.J057_03475	5.871e-19	93.0	COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,467S1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_3987031_0	1121091.AUMP01000008_gene3554	1.975e-234	738.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli	91061|Bacilli	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
GDHHQS3_k127_3987031_28	1267535.KB906767_gene5001	6.772e-39	163.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GDHHQS3_k127_3987031_7	459349.CLOAM1245	1.616e-123	407.0	COG0436@1|root,COG0436@2|Bacteria,2NP0E@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
GDHHQS3_k127_3987031_6	1122194.AUHU01000004_gene1633	5.864e-126	433.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,464AG@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	CoA-transferase family III	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GDHHQS3_k127_3987031_10	338969.Rfer_1098	3.508e-114	393.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,2VJ0E@28216|Betaproteobacteria,4AEN9@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_3987031_30	1122137.AQXF01000006_gene813	1.155e-37	158.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,2U86Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987031_20	379066.GAU_3854	1.683e-70	257.0	COG3174@1|root,COG3174@2|Bacteria,1ZUTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
GDHHQS3_k127_3987031_8	1125863.JAFN01000001_gene3353	1.338e-118	399.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS3_k127_3987031_11	1232410.KI421421_gene3869	3.394e-104	364.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS3_k127_3987031_46	360095.BARBAKC583_0943	1.601e-05	58.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,48TDR@772|Bartonellaceae	28211|Alphaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS3_k127_3987031_13	1089550.ATTH01000001_gene1497	5.845e-101	340.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1FJ2E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_3987364_15	401053.AciPR4_3363	4.451e-18	99.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GDHHQS3_k127_3987364_19	1340493.JNIF01000004_gene509	2.046e-05	57.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y9AH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987364_2	452637.Oter_1902	5.23e-130	430.0	COG5000@1|root,COG5000@2|Bacteria,46V9C@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS3_k127_3987364_1	234267.Acid_4168	1.669e-183	584.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_3987364_18	743525.TSC_c08680	1.205e-06	60.0	COG2220@1|root,COG2220@2|Bacteria,1WJG1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GDHHQS3_k127_3987364_7	1382359.JIAL01000001_gene2773	1.306e-94	322.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria,2JHYU@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_3987364_9	861299.J421_0393	8.093e-64	248.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0393|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987364_6	251221.35211765	1.932e-100	357.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_3987364_14	521674.Plim_2833	1.85e-19	95.0	2EDEG@1|root,337AV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987364_8	1266925.JHVX01000001_gene2549	2.931e-73	254.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,3723D@32003|Nitrosomonadales	28216|Betaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GDHHQS3_k127_3987364_13	926549.KI421517_gene3213	4.866e-27	117.0	COG2259@1|root,COG2259@2|Bacteria,4PB3J@976|Bacteroidetes,47V4B@768503|Cytophagia	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
GDHHQS3_k127_3987364_12	1379270.AUXF01000001_gene2602	1.144e-27	112.0	COG1278@1|root,COG1278@2|Bacteria,1ZV0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Ribonuclease B OB domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_3987364_5	1123242.JH636434_gene4662	7.38e-123	413.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_3987364_11	118168.MC7420_1784	8.38e-38	145.0	COG4251@1|root,COG4251@2|Bacteria,1G7XH@1117|Cyanobacteria,1HCDW@1150|Oscillatoriales	1117|Cyanobacteria	T	KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
GDHHQS3_k127_3987364_0	316067.Geob_3570	3.839e-221	701.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS3_k127_3987364_17	1278073.MYSTI_01803	5.063e-16	89.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	araC	-	-	ko:K21701	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding_2,HTH_18
GDHHQS3_k127_3987364_20	204669.Acid345_3839	2.678e-05	49.0	COG0457@1|root,COG0457@2|Bacteria,3Y893@57723|Acidobacteria,2JNSA@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3987364_4	269799.Gmet_1669	5.606e-125	431.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_3987364_16	522306.CAP2UW1_2790	3.096e-16	94.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VUUB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
GDHHQS3_k127_3987364_3	1121013.P873_05695	2.095e-129	451.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RQ3H@1236|Gammaproteobacteria,1XDDB@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS3_k127_3987364_10	1384054.N790_09605	1.542e-45	183.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS3_k127_4038794_3	234267.Acid_4497	9.402e-115	397.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y44T@57723|Acidobacteria	57723|Acidobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,Trans_reg_C
GDHHQS3_k127_4038794_4	234267.Acid_2199	2.566e-92	318.0	COG0477@1|root,COG2814@2|Bacteria,3Y2VT@57723|Acidobacteria	57723|Acidobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_4038794_0	323097.Nham_0715	2.321e-204	644.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,3JS50@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	MA20_19675	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
GDHHQS3_k127_4038794_8	479434.Sthe_2760	5.168e-09	69.0	COG0454@1|root,COG0456@2|Bacteria,2G9QT@200795|Chloroflexi	200795|Chloroflexi	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_4038794_7	388399.SSE37_16253	1.239e-29	132.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2TSTR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid desaturase	MA20_28095	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GDHHQS3_k127_4038794_6	1121033.AUCF01000010_gene4394	1.509e-49	194.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,2TZJQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
GDHHQS3_k127_4038794_5	118168.MC7420_310	1.42e-67	246.0	2EBR9@1|root,335R6@2|Bacteria,1GBC6@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GDHHQS3_k127_4038794_2	234267.Acid_0802	5.428e-135	444.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_4038794_1	1278073.MYSTI_03434	1.354e-159	510.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
GDHHQS3_k127_4041471_3	1280946.HY29_06185	8.287e-29	119.0	COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,2U5IB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
GDHHQS3_k127_4041471_2	861299.J421_2050	7.75e-29	125.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
GDHHQS3_k127_4041471_0	1121920.AUAU01000022_gene2448	8.34e-59	217.0	COG1434@1|root,COG1434@2|Bacteria,3Y4FT@57723|Acidobacteria	57723|Acidobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GDHHQS3_k127_4041471_1	1340493.JNIF01000003_gene3660	6.151e-50	189.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS3_k127_40886_10	1242864.D187_009687	9.512e-72	252.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria,2YWGV@29|Myxococcales	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GDHHQS3_k127_40886_5	215803.DB30_4349	2.717e-109	375.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYJ0@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
GDHHQS3_k127_40886_12	1210884.HG799463_gene9431	7.749e-54	204.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,TMEM189_B_dmain
GDHHQS3_k127_40886_3	331869.BAL199_18253	5.603e-145	482.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,4BPEH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS3_k127_40886_1	1340493.JNIF01000004_gene652	1.245e-232	735.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_40886_11	1128427.KB904821_gene174	2.713e-59	217.0	COG0705@1|root,COG0705@2|Bacteria,1G5IY@1117|Cyanobacteria,1HF1W@1150|Oscillatoriales	1117|Cyanobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_40886_15	234267.Acid_4212	1.886e-16	89.0	2EQPS@1|root,33I9Q@2|Bacteria,3Y8WF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_40886_14	518766.Rmar_2030	1.646e-16	89.0	COG3762@1|root,COG3762@2|Bacteria,4PEMC@976|Bacteroidetes,1FJAJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pfam:TPM	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_40886_0	1242864.D187_005767	1.094e-287	899.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GDHHQS3_k127_40886_4	383372.Rcas_2645	3.769e-143	501.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
GDHHQS3_k127_40886_6	215803.DB30_7441	1.115e-101	354.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2YW96@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GDHHQS3_k127_40886_2	926550.CLDAP_24530	1.768e-200	658.0	COG3158@1|root,COG3158@2|Bacteria	2|Bacteria	P	potassium ion transmembrane transporter activity	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GDHHQS3_k127_40886_7	454957.IA64_18855	1.079e-95	350.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1X3FI@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
GDHHQS3_k127_40886_8	84531.JMTZ01000142_gene388	6.91e-94	335.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,1X4EK@135614|Xanthomonadales	135614|Xanthomonadales	T	regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_40886_9	861299.J421_2273	4.243e-73	275.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_40886_13	234267.Acid_1239	3.731e-37	158.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,Response_reg,SpoIIE
GDHHQS3_k127_4245168_7	215803.DB30_7075	8.173e-96	340.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS3_k127_4245168_30	398767.Glov_1247	1.048e-26	117.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS3_k127_4245168_24	945713.IALB_1358	8.104e-38	159.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
GDHHQS3_k127_4245168_47	313598.MED152_05760	8.931e-08	60.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia,3VWIN@52959|Polaribacter	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
GDHHQS3_k127_4245168_45	1125863.JAFN01000001_gene268	5.257e-13	75.0	COG0848@1|root,COG0848@2|Bacteria,1NN40@1224|Proteobacteria,42XMQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GDHHQS3_k127_4245168_35	1382359.JIAL01000001_gene2434	6.523e-20	100.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
GDHHQS3_k127_4245168_32	903818.KI912268_gene2000	4.39e-25	115.0	COG0745@1|root,COG0745@2|Bacteria	903818.KI912268_gene2000|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4245168_48	1303518.CCALI_02089	1.127e-06	62.0	COG0457@1|root,COG0457@2|Bacteria	1303518.CCALI_02089|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4245168_33	269799.Gmet_1855	3.325e-24	120.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43T0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
GDHHQS3_k127_4245168_13	1121920.AUAU01000005_gene1090	1.758e-73	256.0	COG2884@1|root,COG2884@2|Bacteria	2|Bacteria	D	Cell division ATP-binding protein ftsE	ftsE	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
GDHHQS3_k127_4245168_36	1500894.JQNN01000001_gene955	2.525e-19	102.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,4726N@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS3_k127_4245168_9	743299.Acife_1512	2.926e-91	312.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,2NC5F@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
GDHHQS3_k127_4245168_27	349124.Hhal_1019	6.962e-29	129.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1X2FT@135613|Chromatiales	135613|Chromatiales	S	PFAM Aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
GDHHQS3_k127_4245168_46	224324.aq_064b	7.819e-10	62.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_4245168_29	309801.trd_A0646	5.935e-27	119.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi,27XW3@189775|Thermomicrobia	189775|Thermomicrobia	M	Lytic transglycosylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT
GDHHQS3_k127_4245168_49	1121920.AUAU01000004_gene620	3.126e-06	53.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
GDHHQS3_k127_4245168_25	1121920.AUAU01000014_gene2832	6.745e-33	143.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
GDHHQS3_k127_4245168_41	391625.PPSIR1_04758	2.93e-15	89.0	COG1729@1|root,COG1729@2|Bacteria,1PRB4@1224|Proteobacteria,42UBY@68525|delta/epsilon subdivisions,2WQMR@28221|Deltaproteobacteria,2YVZE@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
GDHHQS3_k127_4245168_38	1380380.JIAX01000008_gene1785	6.038e-17	91.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
GDHHQS3_k127_4245168_17	1120985.AUMI01000015_gene1461	1.196e-59	218.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H407@909932|Negativicutes	909932|Negativicutes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_4245168_44	1123321.KB905815_gene3316	5.03e-13	79.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS3_k127_4245168_14	649638.Trad_2139	2.749e-73	269.0	COG0648@1|root,COG0648@2|Bacteria,1WJAH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS3_k127_4245168_11	234267.Acid_7135	7.044e-77	275.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria	57723|Acidobacteria	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GDHHQS3_k127_4245168_6	644966.Tmar_1010	1.531e-104	353.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WCSG@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
GDHHQS3_k127_4245168_31	1121957.ATVL01000011_gene3888	2.221e-25	121.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS3_k127_4245168_10	760568.Desku_2556	1.259e-88	301.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS3_k127_4245168_20	880072.Desac_0139	1.258e-53	201.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS3_k127_4245168_40	1408424.JHYI01000010_gene570	5.189e-16	87.0	COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,4HFU6@91061|Bacilli,1ZRCR@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS3_k127_4245168_15	861299.J421_2983	4.4e-65	231.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GDHHQS3_k127_4245168_18	765912.Thimo_2807	6.416e-58	213.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RQ6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HP	ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS3_k127_4245168_19	1278078.G419_20730	4.123e-57	212.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4FUBI@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS3_k127_4245168_28	448385.sce8314	8.553e-29	135.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2YVK6@29|Myxococcales	28221|Deltaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS3_k127_4245168_16	631362.Thi970DRAFT_04791	8.364e-63	238.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales	135613|Chromatiales	H	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_4245168_42	644282.Deba_0361	4.68e-14	87.0	2CG1Y@1|root,32WID@2|Bacteria,1N01A@1224|Proteobacteria,42UK0@68525|delta/epsilon subdivisions,2WQED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,PapD-like
GDHHQS3_k127_4245168_5	589865.DaAHT2_1931	5.637e-122	426.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_4245168_8	448385.sce7280	7.233e-92	322.0	2DB7W@1|root,2Z7P1@2|Bacteria,1N65F@1224|Proteobacteria,434RW@68525|delta/epsilon subdivisions,2X8ZY@28221|Deltaproteobacteria,2Z17U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
GDHHQS3_k127_4245168_43	1336208.JADY01000004_gene3512	9.977e-14	82.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,2JTEK@204441|Rhodospirillales	204441|Rhodospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
GDHHQS3_k127_4245168_0	521674.Plim_0176	4.28e-229	719.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS3_k127_4245168_12	1210884.HG799471_gene14582	4.687e-76	266.0	COG0224@1|root,COG0224@2|Bacteria,2IXDI@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GDHHQS3_k127_4245168_1	575540.Isop_0553	7.46e-212	672.0	COG0056@1|root,COG0056@2|Bacteria,2IXN5@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS3_k127_4245168_26	1123508.JH636439_gene885	3.634e-29	124.0	COG0712@1|root,COG0712@2|Bacteria,2J09A@203682|Planctomycetes	203682|Planctomycetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GDHHQS3_k127_4245168_34	1142394.PSMK_01970	1.248e-22	109.0	COG0711@1|root,COG0711@2|Bacteria,2J0VZ@203682|Planctomycetes	203682|Planctomycetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS3_k127_4245168_39	1268240.ATFI01000007_gene355	1.869e-16	85.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS3_k127_4245168_22	1142394.PSMK_01950	2.252e-44	176.0	COG0356@1|root,COG0356@2|Bacteria,2IZP5@203682|Planctomycetes	203682|Planctomycetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS3_k127_4245168_2	84531.JMTZ01000088_gene1481	1.873e-184	609.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales	135614|Xanthomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	dhs1	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
GDHHQS3_k127_4245168_3	997346.HMPREF9374_2400	1.393e-160	524.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,27B3Y@186824|Thermoactinomycetaceae	91061|Bacilli	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS3_k127_4245168_23	667014.Thein_0380	2.919e-44	170.0	COG0698@1|root,COG0698@2|Bacteria,2GH7Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS3_k127_4245168_37	1123073.KB899241_gene2608	3.465e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4245168_4	1121104.AQXH01000001_gene1400	3.732e-158	515.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_4245168_21	216432.CA2559_02210	5.071e-51	186.0	COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia	976|Bacteroidetes	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
GDHHQS3_k127_4264289_30	1479239.JQMU01000001_gene2127	1.195e-38	149.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,2K3KF@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS3_k127_4264289_19	1121920.AUAU01000017_gene1216	4.971e-66	241.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GDHHQS3_k127_4264289_38	1380394.JADL01000002_gene1601	6.97e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,2JTV5@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
GDHHQS3_k127_4264289_40	1226994.AMZB01000121_gene3420	2.831e-23	106.0	COG1846@1|root,COG1846@2|Bacteria,1RF3U@1224|Proteobacteria,1S4H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GDHHQS3_k127_4264289_16	1227499.C493_09600	1.382e-73	258.0	COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,23T5H@183963|Halobacteria	183963|Halobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	nikC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_4264289_10	1499967.BAYZ01000076_gene838	4.571e-105	349.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_4264289_1	1444306.JFZC01000009_gene1914	2.209e-207	710.0	COG0714@1|root,COG1112@1|root,COG0714@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli	91061|Bacilli	L	Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
GDHHQS3_k127_4264289_17	448385.sce6324	8.48e-72	276.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
GDHHQS3_k127_4264289_13	335543.Sfum_2720	1.632e-82	291.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,2MQGI@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS3_k127_4264289_14	1232410.KI421412_gene446	2.327e-80	278.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,42Q0E@68525|delta/epsilon subdivisions,2WITX@28221|Deltaproteobacteria,43SDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
GDHHQS3_k127_4264289_15	1209984.BN978_04074	2.394e-77	298.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,23EHB@1762|Mycobacteriaceae	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GDHHQS3_k127_4264289_47	502025.Hoch_2240	5.199e-09	72.0	COG2268@1|root,COG5412@1|root,COG2268@2|Bacteria,COG5412@2|Bacteria,1PE3X@1224|Proteobacteria,4335I@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4264289_49	645465.ACUR01000459_gene3059	3.092e-08	66.0	2EMKX@1|root,33F9A@2|Bacteria,2GPG2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4264289_32	1499967.BAYZ01000186_gene3960	6.399e-34	139.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
GDHHQS3_k127_4264289_25	1123276.KB893279_gene2202	5.427e-52	203.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_4264289_12	1121106.JQKB01000021_gene1743	7.769e-103	345.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales	204441|Rhodospirillales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS3_k127_4264289_18	671143.DAMO_2629	3.371e-71	255.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS3_k127_4264289_20	671143.DAMO_2630	1.083e-62	237.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS3_k127_4264289_37	243231.GSU0926	1.056e-27	127.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43TRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS3_k127_4264289_8	1123371.ATXH01000019_gene615	2.597e-108	360.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_4264289_7	314278.NB231_08420	6.3e-116	408.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_4264289_44	547144.HydHO_1540	8.507e-12	78.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GDHHQS3_k127_4264289_34	55529.EKX50224	2.23e-31	141.0	KOG1021@1|root,KOG1021@2759|Eukaryota	2759|Eukaryota	S	macromolecule glycosylation	GUT1	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009832,GO:0009834,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0010417,GO:0012505,GO:0015020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0031410,GO:0031982,GO:0031984,GO:0033692,GO:0034637,GO:0034645,GO:0042285,GO:0042546,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045491,GO:0045492,GO:0047517,GO:0070589,GO:0070592,GO:0071554,GO:0071669,GO:0071704,GO:0071840,GO:0080116,GO:0097708,GO:0098791,GO:1901576	-	ko:K20870,ko:K20889	-	-	-	-	ko00000,ko01000,ko01003	-	GT47	-	Exostosin
GDHHQS3_k127_4264289_31	1121439.dsat_1795	3.474e-35	151.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
GDHHQS3_k127_4264289_6	204669.Acid345_2395	3.999e-120	433.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_4264289_4	204669.Acid345_1052	1.322e-130	450.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
GDHHQS3_k127_4264289_36	211165.AJLN01000153_gene631	4.573e-28	122.0	COG5611@1|root,COG5611@2|Bacteria,1G6XT@1117|Cyanobacteria,1JIY0@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_4264289_43	195250.CM001776_gene338	2.427e-18	89.0	COG2002@1|root,COG2002@2|Bacteria,1G9J8@1117|Cyanobacteria	1117|Cyanobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
GDHHQS3_k127_4264289_24	760192.Halhy_1193	1.176e-53	199.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IXTS@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS3_k127_4264289_22	118173.KB235914_gene2618	5.848e-61	231.0	COG2071@1|root,COG2071@2|Bacteria,1G5CB@1117|Cyanobacteria,1HANP@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS3_k127_4264289_2	316057.RPD_1593	2.494e-161	520.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,3JTIE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_4264289_3	945713.IALB_1403	4.964e-135	467.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_4264289_45	379066.GAU_0167	1.074e-11	70.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
GDHHQS3_k127_4264289_52	558884.JRGM01000032_gene600	4.44e-05	55.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1Y3FT@135624|Aeromonadales	135624|Aeromonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
GDHHQS3_k127_4264289_21	1121438.JNJA01000002_gene3482	2.174e-61	225.0	COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2
GDHHQS3_k127_4264289_51	1238182.C882_2080	1.587e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1RK4Q@1224|Proteobacteria,2UBBB@28211|Alphaproteobacteria,2JSKY@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_9
GDHHQS3_k127_4264289_9	215803.DB30_1749	1.629e-106	359.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS3_k127_4264289_26	1434325.AZQN01000001_gene452	2.861e-49	186.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GDHHQS3_k127_4264289_29	882083.SacmaDRAFT_4559	2.333e-40	168.0	COG0500@1|root,COG2226@2|Bacteria,2GZW7@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12
GDHHQS3_k127_4264289_35	479434.Sthe_2076	1.012e-30	136.0	COG1215@1|root,COG1215@2|Bacteria,2GBNF@200795|Chloroflexi,27YBR@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GDHHQS3_k127_4264289_39	671143.DAMO_2655	3.375e-26	114.0	COG0720@1|root,COG0720@2|Bacteria,2NR6T@2323|unclassified Bacteria	2|Bacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_4264289_28	357808.RoseRS_0607	1.33e-44	183.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
GDHHQS3_k127_4264289_23	240015.ACP_2578	4.353e-55	214.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria,2JI9H@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GDHHQS3_k127_4264289_5	706587.Desti_2694	1.534e-126	414.0	COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria	1224|Proteobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
GDHHQS3_k127_4264289_46	266264.Rmet_4532	9.238e-11	73.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VIVR@28216|Betaproteobacteria,1K2PA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114,ko:K16257	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS3_k127_4264289_27	1292034.OR37_02962	3.975e-47	182.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS3_k127_4264289_0	1449069.JMLO01000001_gene2266	2.602e-262	818.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4FWX5@85025|Nocardiaceae	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1552	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_4264289_11	1123024.AUII01000011_gene4421	1.064e-104	347.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DZZS@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1553	Fer2_3,Fer4_10,Fer4_8
GDHHQS3_k127_4264289_41	1449069.JMLO01000001_gene2264	4.805e-21	104.0	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
GDHHQS3_k127_4264289_42	1122138.AQUZ01000004_gene891	2.429e-19	101.0	COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1555	Fumarate_red_D
GDHHQS3_k127_4264289_33	204669.Acid345_1386	9.93e-34	142.0	2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4264289_48	76636.JOEC01000002_gene2136	1.446e-08	60.0	COG1451@1|root,COG1451@2|Bacteria,2I3WR@201174|Actinobacteria,4FNHP@85023|Microbacteriaceae	201174|Actinobacteria	S	SprT homologues.	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
GDHHQS3_k127_4318945_3	765698.Mesci_3993	2.397e-08	66.0	COG0671@1|root,COG0671@2|Bacteria,1RF6B@1224|Proteobacteria,2U8U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GDHHQS3_k127_4318945_2	1499967.BAYZ01000193_gene3921	1.498e-71	254.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
GDHHQS3_k127_4318945_1	1123389.ATXJ01000021_gene1077	1.205e-82	293.0	COG2148@1|root,COG2148@2|Bacteria,1WIX1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_4318945_0	326427.Cagg_1989	1.907e-155	496.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_4462867_6	292415.Tbd_2287	7.567e-95	319.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
GDHHQS3_k127_4462867_24	1380391.JIAS01000001_gene2744	1.923e-27	126.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,2JSGU@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS3_k127_4462867_19	1205680.CAKO01000029_gene5240	4.762e-41	173.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RNA signal recognition particle 4.5S RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
GDHHQS3_k127_4462867_18	59538.XP_005972888.1	1.565e-45	175.0	COG0251@1|root,KOG2317@2759|Eukaryota	2759|Eukaryota	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_4462867_10	1121939.L861_19245	1.455e-89	312.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS3_k127_4462867_3	869210.Marky_1927	4.603e-175	565.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS3_k127_4462867_27	767817.Desgi_3358	2.431e-13	74.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,262YN@186807|Peptococcaceae	186801|Clostridia	KT	Stress-responsive transcriptional regulator	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
GDHHQS3_k127_4462867_11	1244869.H261_12579	2.489e-88	325.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2JPUZ@204441|Rhodospirillales	204441|Rhodospirillales	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084,ko:K08344	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
GDHHQS3_k127_4462867_26	1035197.HMPREF9999_00702	8.746e-14	85.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,2FSXM@200643|Bacteroidia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
GDHHQS3_k127_4462867_8	338966.Ppro_2189	5.074e-92	328.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,43TQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_4462867_1	251221.35213714	4.904e-233	743.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
GDHHQS3_k127_4462867_12	1303518.CCALI_00300	2.95e-83	291.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GDHHQS3_k127_4462867_2	234267.Acid_1818	3.334e-179	584.0	COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase M13	-	-	3.4.24.71	ko:K01415	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
GDHHQS3_k127_4462867_15	266117.Rxyl_0489	5.329e-72	249.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS3_k127_4462867_14	1121013.P873_12075	4.803e-75	259.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_4462867_16	1248917.ANFX01000029_gene2625	1.045e-57	215.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,2U25J@28211|Alphaproteobacteria,2K813@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_4462867_0	502025.Hoch_0166	1.498e-275	861.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_4462867_22	518766.Rmar_0951	3.503e-35	147.0	COG3264@1|root,COG3264@2|Bacteria,4PKDP@976|Bacteroidetes	976|Bacteroidetes	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
GDHHQS3_k127_4462867_28	639030.JHVA01000001_gene284	7.444e-12	70.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS3_k127_4462867_13	313624.NSP_14580	8.197e-78	279.0	COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria,1HIC7@1161|Nostocales	1117|Cyanobacteria	C	FAD binding domain	-	-	1.1.3.8,1.5.99.12	ko:K00103,ko:K00279	ko00053,ko00908,ko01100,map00053,map00908,map01100	M00129	R00647,R03184,R05708,R10053	RC00121,RC00195,RC00346,RC00869,RC01455	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,Cytokin-bind,FAD_binding_4
GDHHQS3_k127_4462867_9	1133849.O3I_031645	2.599e-91	312.0	COG1181@1|root,COG1181@2|Bacteria,2I8SB@201174|Actinobacteria,4G09W@85025|Nocardiaceae	201174|Actinobacteria	M	D-ala D-ala ligase C-terminus	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_4462867_7	932678.THERU_06075	3.336e-93	315.0	COG2107@1|root,COG2107@2|Bacteria,2G4EE@200783|Aquificae	200783|Aquificae	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_4462867_21	1123072.AUDH01000020_gene2059	3.731e-37	153.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,2JSSB@204441|Rhodospirillales	204441|Rhodospirillales	S	Phosphoglycolate phosphatase	cbbZ	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_4462867_20	290397.Adeh_0620	1.437e-37	145.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2YVFS@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_4462867_17	1519464.HY22_14185	1.484e-55	221.0	COG1266@1|root,COG2208@1|root,COG1266@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07052,ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Abi,GAF_2,GAF_3,SpoIIE
GDHHQS3_k127_4462867_23	247639.MGP2080_13924	3.973e-29	130.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1J5P5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	adrA	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K18968	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.2	-	iECSF_1327.ECSF_0346,ic_1306.c0492	GGDEF,MASE2
GDHHQS3_k127_4462867_4	204669.Acid345_3875	1.236e-137	448.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS3_k127_4462867_5	903818.KI912268_gene1335	9.57e-119	391.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria	57723|Acidobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS3_k127_4462867_25	251221.35211983	5.936e-20	93.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4514541_2	382464.ABSI01000009_gene3971	8.407e-43	160.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS3_k127_4514541_0	926550.CLDAP_16780	6.814e-146	477.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS3_k127_4514541_1	448385.sce5973	9.92e-109	358.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_4569694_20	1382356.JQMP01000003_gene1474	4.463e-109	373.0	COG1878@1|root,COG1878@2|Bacteria,2GBE2@200795|Chloroflexi,27Z29@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS3_k127_4569694_9	644966.Tmar_1475	1.207e-144	491.0	COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia,3WCTN@538999|Clostridiales incertae sedis	186801|Clostridia	C	Protein of unknown function (DUF1116)	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,DUF1116,Ligase_CoA
GDHHQS3_k127_4569694_17	795797.C497_05402	8.069e-113	386.0	COG0154@1|root,arCOG01717@2157|Archaea,2XV02@28890|Euryarchaeota,23TIC@183963|Halobacteria	183963|Halobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GDHHQS3_k127_4569694_37	1382356.JQMP01000003_gene1477	1.981e-61	235.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_4569694_30	1382356.JQMP01000001_gene1179	2.544e-76	286.0	COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_4569694_19	1278073.MYSTI_07744	2.701e-109	391.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WKRR@28221|Deltaproteobacteria,2YUIY@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD4	-	-	ko:K18660,ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_4569694_42	867903.ThesuDRAFT_00051	6.326e-53	214.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3WD9P@538999|Clostridiales incertae sedis	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4569694_0	1267535.KB906767_gene2727	4.293e-236	742.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS3_k127_4569694_48	1499967.BAYZ01000171_gene5602	2.561e-38	147.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS3_k127_4569694_6	243231.GSU1690	8.83e-165	532.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GDHHQS3_k127_4569694_29	1125863.JAFN01000001_gene506	2.894e-77	297.0	COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
GDHHQS3_k127_4569694_45	204669.Acid345_2474	2.664e-45	190.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GDHHQS3_k127_4569694_36	404380.Gbem_2445	1.221e-61	233.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS3_k127_4569694_32	644282.Deba_1926	3.081e-71	250.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS3_k127_4569694_3	269799.Gmet_1934	2.622e-221	704.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,43UFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GDHHQS3_k127_4569694_35	743721.Psesu_2220	3.88e-63	243.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1X40B@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_4569694_54	1340493.JNIF01000003_gene3926	1.017e-20	105.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS3_k127_4569694_61	1379270.AUXF01000002_gene1514	1.578e-05	52.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
GDHHQS3_k127_4569694_7	760192.Halhy_5448	1.455e-161	519.0	COG2227@1|root,COG2227@2|Bacteria,4NK04@976|Bacteroidetes	976|Bacteroidetes	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
GDHHQS3_k127_4569694_40	414684.RC1_3777	9.17e-60	212.0	COG1898@1|root,COG1898@2|Bacteria,1RDAB@1224|Proteobacteria,2U99D@28211|Alphaproteobacteria,2JSSZ@204441|Rhodospirillales	204441|Rhodospirillales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS3_k127_4569694_10	887898.HMPREF0551_2407	1.458e-144	471.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,2VM14@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
GDHHQS3_k127_4569694_52	197221.22294573	2.299e-27	118.0	COG1045@1|root,COG1045@2|Bacteria,1G0WM@1117|Cyanobacteria	1117|Cyanobacteria	E	Serine acetyltransferase	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
GDHHQS3_k127_4569694_44	306281.AJLK01000150_gene1904	1.841e-49	186.0	COG1209@1|root,COG1209@2|Bacteria,1G0RG@1117|Cyanobacteria,1JI9G@1189|Stigonemataceae	1117|Cyanobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_4569694_41	1499967.BAYZ01000073_gene2049	7.462e-58	229.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
GDHHQS3_k127_4569694_38	429009.Adeg_0700	4.446e-61	238.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS3_k127_4569694_14	383372.Rcas_3093	2.255e-120	396.0	COG0451@1|root,COG0451@2|Bacteria,2GAMV@200795|Chloroflexi,376SP@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_4569694_43	1384056.N787_07775	1.052e-52	193.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales	135614|Xanthomonadales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS3_k127_4569694_26	460265.Mnod_4186	1.796e-85	292.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,1JRFW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_4569694_12	504728.K649_13715	3.222e-124	420.0	COG0451@1|root,COG0451@2|Bacteria,1WNCR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS3_k127_4569694_8	526227.Mesil_2957	6.116e-158	507.0	COG0156@1|root,COG0156@2|Bacteria,1WIXA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_4569694_34	1121405.dsmv_0227	6.824e-65	246.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2MISH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4569694_57	247156.NFA_35830	1.344e-16	91.0	COG1670@1|root,COG1670@2|Bacteria,2HIKV@201174|Actinobacteria,4G4AH@85025|Nocardiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_4569694_5	1155714.KB891993_gene5692	2.263e-176	567.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_4569694_21	710421.Mycch_3320	4.714e-108	361.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,236ZW@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
GDHHQS3_k127_4569694_13	649638.Trad_1794	3.785e-123	420.0	COG1064@1|root,COG1064@2|Bacteria,1WIXW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
GDHHQS3_k127_4569694_28	383372.Rcas_2075	3.677e-82	284.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_4569694_16	247490.KSU1_C0355	1.738e-114	388.0	COG1322@1|root,COG1322@2|Bacteria,2J2TY@203682|Planctomycetes	203682|Planctomycetes	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
GDHHQS3_k127_4569694_47	1379270.AUXF01000002_gene1135	1.763e-41	169.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4569694_53	865937.Gilli_2897	2.923e-25	111.0	COG1764@1|root,COG1764@2|Bacteria,4PK2K@976|Bacteroidetes,1IGG0@117743|Flavobacteriia,2P7S9@244698|Gillisia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS3_k127_4569694_56	1002340.AFCF01000033_gene3900	6.191e-17	88.0	COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_4569694_51	243231.GSU2335	4.811e-29	129.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_4569694_25	240016.ABIZ01000001_gene2031	9.632e-87	297.0	COG1082@1|root,COG1082@2|Bacteria,46VY2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	iolE	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS3_k127_4569694_23	589865.DaAHT2_1228	5.014e-95	333.0	28P28@1|root,2ZBYC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4569694_22	266117.Rxyl_0655	6.984e-96	321.0	COG0428@1|root,COG0428@2|Bacteria,2HEM8@201174|Actinobacteria	201174|Actinobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GDHHQS3_k127_4569694_33	639030.JHVA01000001_gene3713	1.439e-68	242.0	COG2823@1|root,COG2823@2|Bacteria,3Y7T6@57723|Acidobacteria,2JN0K@204432|Acidobacteriia	204432|Acidobacteriia	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS3_k127_4569694_58	1137271.AZUM01000003_gene3718	3.041e-11	70.0	COG0517@1|root,COG0517@2|Bacteria,2IM3K@201174|Actinobacteria,4E58F@85010|Pseudonocardiales	201174|Actinobacteria	S	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_4569694_59	443152.MDG893_01640	7.311e-10	63.0	2EHHF@1|root,33B9C@2|Bacteria,1NM2H@1224|Proteobacteria,1STI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4569694_46	706587.Desti_2663	5.908e-43	174.0	COG1503@1|root,COG1503@2|Bacteria,1MXX2@1224|Proteobacteria,42U2M@68525|delta/epsilon subdivisions,2WQS1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4569694_31	1340434.AXVA01000005_gene4503	6.736e-73	269.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli,1ZS1S@1386|Bacillus	91061|Bacilli	E	methionine gamma-lyase	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_4569694_4	867903.ThesuDRAFT_00352	8.235e-198	638.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
GDHHQS3_k127_4569694_1	344747.PM8797T_16213	6.788e-235	741.0	COG2217@1|root,COG2217@2|Bacteria,2IXE1@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
GDHHQS3_k127_4569694_18	1408473.JHXO01000010_gene3699	1.354e-110	370.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
GDHHQS3_k127_4569694_15	926562.Oweho_3326	4.545e-120	398.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4569694_11	1313421.JHBV01000007_gene4261	1.34e-124	424.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IQQ0@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4569694_27	1168034.FH5T_10690	1.601e-84	301.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,2FNRG@200643|Bacteroidia	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_4569694_49	1260251.SPISAL_05310	1.971e-33	132.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1WZ3B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1820)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1820
GDHHQS3_k127_4569694_50	350054.Mflv_0473	1.883e-29	122.0	COG3011@1|root,COG3011@2|Bacteria,2IJRX@201174|Actinobacteria,239I3@1762|Mycobacteriaceae	201174|Actinobacteria	S	Thiol-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
GDHHQS3_k127_4569694_2	404589.Anae109_0161	1.516e-228	721.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YXH5@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS3_k127_4569694_24	404589.Anae109_0160	3.413e-88	305.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KQ	Methyltransferase type 11	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
GDHHQS3_k127_4569694_39	1122603.ATVI01000007_gene1557	6.757e-61	238.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
GDHHQS3_k127_4569694_60	1123060.JONP01000004_gene618	3.414e-08	64.0	2DWIE@1|root,340GU@2|Bacteria,1NZ7I@1224|Proteobacteria,2USW7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4572178_11	1502851.FG93_05234	5.131e-49	196.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,3K2CR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS3_k127_4572178_9	331869.BAL199_17133	1.95e-56	210.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,4BSKZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,1.5.1.1,4.3.1.12	ko:K01750,ko:K19244,ko:K19743	ko00250,ko00310,ko00330,ko00430,ko00960,ko01100,ko01110,ko01130,ko01230,map00250,map00310,map00330,map00430,map00960,map01100,map01110,map01130,map01230	-	R00396,R00671,R01246,R01249,R02201,R02203	RC00008,RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_4572178_12	441620.Mpop_1890	1.461e-45	175.0	COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,1JTFS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	SMART Rhodanese domain protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,Rhodanese
GDHHQS3_k127_4572178_0	1254432.SCE1572_26495	1.484e-244	791.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
GDHHQS3_k127_4572178_3	1123073.KB899245_gene94	1.386e-164	529.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1S9NJ@1236|Gammaproteobacteria,1X5C8@135614|Xanthomonadales	135614|Xanthomonadales	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.12.1	ko:K16319	ko00627,ko01120,map00627,map01120	M00637	R00823,R00825	RC00192	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
GDHHQS3_k127_4572178_6	1123073.KB899241_gene2287	5.759e-122	403.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_4572178_1	204669.Acid345_1270	6.198e-202	662.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GDHHQS3_k127_4572178_8	234267.Acid_7336	1.431e-87	308.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GDHHQS3_k127_4572178_2	483219.LILAB_25795	6.528e-170	553.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS3_k127_4572178_10	1297742.A176_07251	3.451e-50	197.0	2BVHD@1|root,32QVZ@2|Bacteria,1N6CE@1224|Proteobacteria,430V5@68525|delta/epsilon subdivisions,2X3NG@28221|Deltaproteobacteria,2YWNE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_4572178_7	204669.Acid345_1504	2.237e-121	405.0	COG2195@1|root,COG2195@2|Bacteria,3Y6CZ@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_4572178_13	204669.Acid345_1629	1.313e-22	114.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria,2JJNM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4572178_4	861299.J421_4258	2.56e-161	524.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GDHHQS3_k127_4572178_5	1144275.COCOR_01696	3.177e-134	435.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2Z30B@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
GDHHQS3_k127_4621402_0	880073.Calab_1317	0.0	1125.0	COG2609@1|root,COG2609@2|Bacteria,2NQAC@2323|unclassified Bacteria	2|Bacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GDHHQS3_k127_4621402_1	316067.Geob_1944	1.127e-121	417.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43T1R@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
GDHHQS3_k127_4621402_2	448385.sce0899	1.66e-29	122.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria	1224|Proteobacteria	K	Fibronectin fibrinogen-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GDHHQS3_k127_4644948_5	234267.Acid_4272	9.122e-130	444.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_7	861299.J421_6141	8.762e-127	443.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_6141|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4644948_29	204669.Acid345_1284	5.323e-34	134.0	COG1695@1|root,COG1695@2|Bacteria,3Y5C5@57723|Acidobacteria,2JNCX@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_4644948_2	234267.Acid_4795	1.682e-147	501.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_35	83406.HDN1F_07830	1.346e-08	69.0	COG1512@1|root,COG1512@2|Bacteria,1RDS2@1224|Proteobacteria,1S5J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	PDZ_2,TPM_phosphatase
GDHHQS3_k127_4644948_17	234267.Acid_2611	6.193e-69	262.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_4	204669.Acid345_2047	2.501e-133	455.0	COG0577@1|root,COG0577@2|Bacteria,3Y6R1@57723|Acidobacteria,2JMKX@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_9	861299.J421_0601	2.152e-122	430.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_6	861299.J421_6139	2.536e-129	443.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_16	861299.J421_0332	3.454e-75	281.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0332|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4644948_8	251221.35211765	2.163e-126	454.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_1	1267535.KB906767_gene5108	2.574e-148	501.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_19	1500304.JQKY01000014_gene4258	7.294e-61	215.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,2U6UK@28211|Alphaproteobacteria,4BB31@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Phosphoglycerate mutase	gpmB1	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_4644948_12	305700.B447_11897	1.638e-110	370.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VN6W@28216|Betaproteobacteria,2KVGJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4644948_28	1429851.X548_02650	3.744e-35	140.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1X6II@135614|Xanthomonadales	135614|Xanthomonadales	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS3_k127_4644948_25	517417.Cpar_0914	1.446e-46	188.0	28NRA@1|root,2ZBQK@2|Bacteria,1FEPD@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_4644948_30	517417.Cpar_0913	4.213e-32	143.0	COG0204@1|root,COG0204@2|Bacteria,1FDYJ@1090|Chlorobi	1090|Chlorobi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_4644948_32	1121106.JQKB01000004_gene2260	9.51e-14	84.0	COG1366@1|root,COG1366@2|Bacteria,1NECY@1224|Proteobacteria,2UHIF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GDHHQS3_k127_4644948_34	243233.MCA1666	9.415e-10	69.0	COG2172@1|root,COG2172@2|Bacteria,1PVRH@1224|Proteobacteria,1RU0B@1236|Gammaproteobacteria,1XGSJ@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
GDHHQS3_k127_4644948_23	1121106.JQKB01000004_gene2259	6.625e-56	215.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF4388,FHA,GAF,GGDEF,Response_reg,SpoIIE,Trans_reg_C,Yop-YscD_cpl
GDHHQS3_k127_4644948_3	398767.Glov_0604	7.255e-134	472.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,1MUB7@1224|Proteobacteria,42N14@68525|delta/epsilon subdivisions,2WIKT@28221|Deltaproteobacteria,43SHF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4644948_10	861299.J421_2962	9.326e-121	408.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
GDHHQS3_k127_4644948_15	420324.KI911943_gene5343	4.303e-76	264.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_4644948_31	740709.A10D4_12243	1.358e-15	85.0	2CIG1@1|root,33MZH@2|Bacteria,1NPWM@1224|Proteobacteria,1SHNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS3_k127_4644948_18	284031.JNXD01000006_gene2767	1.135e-68	244.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_4644948_20	234267.Acid_2184	6.572e-60	229.0	COG0583@1|root,COG0583@2|Bacteria,3Y8I7@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
GDHHQS3_k127_4644948_11	861299.J421_0959	2.209e-118	410.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_22	260799.BAS2515	3.347e-56	201.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,1ZG53@1386|Bacillus	91061|Bacilli	S	Belongs to the metal hydrolase YfiT family	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_4644948_36	273068.TTE2092	2.297e-08	67.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,1TPK4@1239|Firmicutes,25KEP@186801|Clostridia,42I2X@68295|Thermoanaerobacterales	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT
GDHHQS3_k127_4644948_14	1047013.AQSP01000123_gene1523	1.003e-97	357.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_4644948_33	1278073.MYSTI_05965	5.49e-13	76.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS3_k127_4644948_24	861299.J421_2096	5.381e-53	210.0	COG3279@1|root,COG3279@2|Bacteria,1ZTKG@142182|Gemmatimonadetes	2|Bacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,LytTR,Response_reg
GDHHQS3_k127_4644948_26	1121013.P873_12620	4.27e-45	180.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
GDHHQS3_k127_4644948_38	1122939.ATUD01000022_gene3657	3.08e-05	57.0	COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	lytR	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
GDHHQS3_k127_4644948_21	1121004.ATVC01000015_gene2116	2.806e-57	216.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,2KT4G@206351|Neisseriales	206351|Neisseriales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4644948_0	1278073.MYSTI_02176	2.958e-194	638.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4644948_27	1267535.KB906767_gene2358	4.037e-38	145.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_4644948_13	861299.J421_6226	2.853e-106	375.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_464526_1	765913.ThidrDRAFT_4297	1.126e-134	438.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS3_k127_464526_12	1121946.AUAX01000031_gene977	1.097e-21	107.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4D9SI@85008|Micromonosporales	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
GDHHQS3_k127_464526_5	1267534.KB906755_gene4489	1.555e-77	293.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_464526_3	661478.OP10G_2908	1.098e-96	343.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_464526_10	1267534.KB906755_gene4491	8.15e-46	180.0	COG1566@1|root,COG1566@2|Bacteria,3Y53G@57723|Acidobacteria	57723|Acidobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GDHHQS3_k127_464526_7	316274.Haur_0049	2.876e-67	249.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_464526_2	1183438.GKIL_3422	1.725e-131	445.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_464526_13	1122182.KB903814_gene3390	5.476e-19	98.0	COG0457@1|root,COG0457@2|Bacteria,2H8D0@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_464526_8	1442599.JAAN01000040_gene3002	6.947e-60	224.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1SEZ4@1236|Gammaproteobacteria,1X6A8@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_464526_6	1192034.CAP_1125	3.976e-71	254.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_464526_14	1123256.KB907933_gene2280	6.779e-06	57.0	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria,1XAHR@135614|Xanthomonadales	135614|Xanthomonadales	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_464526_0	745411.B3C1_16471	4.884e-143	472.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J9EE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02481,ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_464526_11	1565129.JSFF01000011_gene1878	6.732e-40	171.0	COG4191@1|root,COG4191@2|Bacteria,1RC0X@1224|Proteobacteria,1S3G6@1236|Gammaproteobacteria,2Q95H@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_464526_4	1123489.AUAN01000002_gene748	1.701e-90	310.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes	909932|Negativicutes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_464526_9	391612.CY0110_12707	2.128e-49	181.0	COG0126@1|root,COG0126@2|Bacteria,1G2FM@1117|Cyanobacteria,3KFNN@43988|Cyanothece	1117|Cyanobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS3_k127_468326_0	439235.Dalk_0513	9.02e-39	167.0	COG0664@1|root,COG1033@1|root,COG2199@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,COG2199@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
GDHHQS3_k127_4715776_18	1403819.BATR01000169_gene5823	1.455e-17	96.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
GDHHQS3_k127_4715776_4	1123024.AUII01000004_gene1701	5.476e-133	426.0	COG1733@1|root,COG1733@2|Bacteria,2I9HE@201174|Actinobacteria,4EEJ7@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GDHHQS3_k127_4715776_1	1037409.BJ6T_23810	3.63e-243	760.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GDHHQS3_k127_4715776_3	1234364.AMSF01000016_gene1553	4.678e-134	441.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1X52A@135614|Xanthomonadales	135614|Xanthomonadales	L	Recombination factor protein RarA	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GDHHQS3_k127_4715776_5	204669.Acid345_4042	2.158e-130	425.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_4715776_0	1379698.RBG1_1C00001G1725	0.0	1219.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
GDHHQS3_k127_4715776_8	1379698.RBG1_1C00001G1724	8.894e-84	293.0	COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS3_k127_4715776_11	290397.Adeh_0651	2.872e-43	183.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
GDHHQS3_k127_4715776_10	383372.Rcas_2563	1.553e-46	175.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi,375N8@32061|Chloroflexia	32061|Chloroflexia	J	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS3_k127_4715776_13	857290.HMPREF9156_00487	7.605e-41	155.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS3_k127_4715776_9	498211.CJA_1435	2.682e-70	254.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1FFS4@10|Cellvibrio	1236|Gammaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS3_k127_4715776_17	446470.Snas_2183	4.761e-23	107.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4EYTZ@85014|Glycomycetales	201174|Actinobacteria	J	RimM N-terminal domain	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_4715776_21	1410618.JNKI01000001_gene1309	2.14e-06	54.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4H5NW@909932|Negativicutes	909932|Negativicutes	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS3_k127_4715776_19	1121472.AQWN01000005_gene2461	2.597e-15	83.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,262DZ@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS3_k127_4715776_2	867903.ThesuDRAFT_00298	5.657e-145	471.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS3_k127_4715776_7	443255.SCLAV_1203	1.042e-99	349.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS3_k127_4715776_12	665571.STHERM_c18790	1.138e-42	165.0	COG0705@1|root,COG0705@2|Bacteria,2JASZ@203691|Spirochaetes	203691|Spirochaetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_4715776_20	382464.ABSI01000009_gene3978	4.685e-13	80.0	2EE3M@1|root,337Y7@2|Bacteria,46VPI@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4715776_6	234267.Acid_2673	2.593e-110	378.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
GDHHQS3_k127_4715776_14	234267.Acid_2672	7.331e-36	147.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
GDHHQS3_k127_47235_2	1144342.PMI40_01760	2.216e-78	266.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,2WH7P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS3_k127_47235_0	1047013.AQSP01000037_gene1322	1.618e-118	396.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294,ko:K13868	ko04974,map04974	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.8.15	-	-	AA_permease_2
GDHHQS3_k127_47235_1	293826.Amet_0039	6.896e-81	286.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,25CA6@186801|Clostridia,36WS4@31979|Clostridiaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_47235_3	1121289.JHVL01000031_gene358	1.668e-29	133.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,36DHD@31979|Clostridiaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
GDHHQS3_k127_4796057_14	521674.Plim_3848	5.812e-98	337.0	COG0152@1|root,COG0152@2|Bacteria,2IY7D@203682|Planctomycetes	203682|Planctomycetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS3_k127_4796057_24	1294143.H681_17515	1.741e-39	156.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GDHHQS3_k127_4796057_10	1125863.JAFN01000001_gene3161	1.074e-124	442.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
GDHHQS3_k127_4796057_17	1121920.AUAU01000002_gene2145	2.145e-66	245.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GDHHQS3_k127_4796057_15	903818.KI912268_gene1551	8.414e-72	252.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria	57723|Acidobacteria	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GDHHQS3_k127_4796057_18	1379281.AVAG01000040_gene807	8.553e-66	248.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2M8PZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GDHHQS3_k127_4796057_19	760568.Desku_1293	2.745e-64	236.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,260IY@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS3_k127_4796057_12	1304880.JAGB01000002_gene2311	2.708e-110	373.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS3_k127_4796057_28	405948.SACE_4612	1.531e-28	121.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria,4ECGK@85010|Pseudonocardiales	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
GDHHQS3_k127_4796057_22	1089546.AQUI01000002_gene969	2.02e-47	178.0	COG1848@1|root,COG1848@2|Bacteria,2IPRK@201174|Actinobacteria,40A5J@622450|Actinopolysporales	201174|Actinobacteria	S	PIN domain	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_4796057_33	83332.Rv3321c	1.063e-20	93.0	2DSQK@1|root,33H2H@2|Bacteria,2H8IS@201174|Actinobacteria,23EB7@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4796057_35	1211814.CAPG01000082_gene3799	2.892e-10	69.0	2BF4Y@1|root,328X8@2|Bacteria,1UB8H@1239|Firmicutes,4IMM8@91061|Bacilli,1ZKEI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4796057_34	502025.Hoch_2488	4.365e-20	97.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2YVUJ@29|Myxococcales	28221|Deltaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GDHHQS3_k127_4796057_8	1047013.AQSP01000045_gene110	9.438e-134	454.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS3_k127_4796057_23	1382359.JIAL01000001_gene476	2.433e-44	170.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS3_k127_4796057_38	395495.Lcho_0755	6.451e-06	58.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,1KK8S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
GDHHQS3_k127_4796057_26	1121920.AUAU01000022_gene2467	1.98e-32	148.0	COG3266@1|root,COG3266@2|Bacteria,3Y4N4@57723|Acidobacteria	57723|Acidobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS3_k127_4796057_40	234267.Acid_2564	0.000104	48.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4796057_25	404589.Anae109_1348	8.495e-35	141.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GDHHQS3_k127_4796057_32	1121438.JNJA01000004_gene606	1.796e-25	115.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2MCER@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS3_k127_4796057_27	1232410.KI421420_gene3159	1.943e-29	130.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS3_k127_4796057_16	562970.Btus_1333	8.917e-68	251.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,2782F@186823|Alicyclobacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_4796057_3	1303518.CCALI_00495	2.865e-160	533.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
GDHHQS3_k127_4796057_13	338966.Ppro_3113	6.07e-109	383.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria,43TF3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
GDHHQS3_k127_4796057_30	1397278.AYMV01000015_gene2203	6.057e-28	132.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4FPP8@85023|Microbacteriaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_4796057_20	649638.Trad_0575	1.395e-62	244.0	COG3823@1|root,COG3823@2|Bacteria,1WM89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
GDHHQS3_k127_4796057_1	1280941.HY2_13090	1.423e-225	728.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,2TUDY@28211|Alphaproteobacteria,43X23@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
GDHHQS3_k127_4796057_21	395964.KE386496_gene802	3.103e-49	203.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,3N9WX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	HAMP domain	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GDHHQS3_k127_4796057_0	941824.TCEL_01674	1.906e-252	788.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,36DK8@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS3_k127_4796057_4	1089550.ATTH01000002_gene11	1.241e-154	512.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1FJ2U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
GDHHQS3_k127_4796057_36	468059.AUHA01000003_gene1874	7.545e-09	59.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IPCD@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GDHHQS3_k127_4796057_31	1121123.AUAO01000002_gene284	9.492e-28	122.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,2KH36@204458|Caulobacterales	204458|Caulobacterales	J	peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GDHHQS3_k127_4796057_5	1267533.KB906737_gene1703	1.074e-149	509.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GDHHQS3_k127_4796057_11	1187851.A33M_3193	1.321e-121	402.0	COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	yphC	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
GDHHQS3_k127_4796057_6	1187851.A33M_3194	7.724e-146	490.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_4796057_9	316056.RPC_1029	9.705e-133	436.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
GDHHQS3_k127_4796057_2	1244869.H261_12286	1.063e-186	607.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
GDHHQS3_k127_4796057_7	1244869.H261_10397	8.869e-146	476.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
GDHHQS3_k127_4805911_4	234267.Acid_4431	5.737e-144	484.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_4805911_12	1045855.DSC_11350	9.235e-59	224.0	COG0500@1|root,COG0500@2|Bacteria,1QWHM@1224|Proteobacteria,1T47V@1236|Gammaproteobacteria,1XCTD@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4805911_14	379066.GAU_3771	2.461e-58	223.0	COG3176@1|root,COG3176@2|Bacteria,1ZUSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
GDHHQS3_k127_4805911_6	583355.Caka_1928	1.484e-109	378.0	COG0189@1|root,COG0586@1|root,COG1073@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG1073@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_4805911_27	203122.Sde_1195	6.486e-22	113.0	COG3332@1|root,COG3332@2|Bacteria,1RE1W@1224|Proteobacteria,1S59Q@1236|Gammaproteobacteria,469A0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
GDHHQS3_k127_4805911_26	382464.ABSI01000005_gene1399	1.296e-27	119.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4805911_9	443143.GM18_1063	2.866e-88	311.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GDHHQS3_k127_4805911_8	909663.KI867150_gene1676	2.438e-96	321.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_4805911_32	1283300.ATXB01000002_gene2605	0.0003618	51.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1XFK1@135618|Methylococcales	135618|Methylococcales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
GDHHQS3_k127_4805911_34	1125973.JNLC01000013_gene4022	0.000553	53.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,3JVE6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	OmpW family	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
GDHHQS3_k127_4805911_13	671143.DAMO_0676	2.313e-58	222.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GDHHQS3_k127_4805911_5	667014.Thein_0694	3.79e-113	376.0	COG1186@1|root,COG1186@2|Bacteria,2GGX5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_4805911_24	1440774.Y900_013925	2.358e-32	134.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,2354F@1762|Mycobacteriaceae	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_4805911_28	69395.JQLZ01000011_gene3550	4.633e-20	101.0	COG3710@1|root,COG3710@2|Bacteria,1QVGV@1224|Proteobacteria,2TWFZ@28211|Alphaproteobacteria,2KK7Q@204458|Caulobacterales	204458|Caulobacterales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
GDHHQS3_k127_4805911_33	1121127.JAFA01000046_gene6851	0.0005468	51.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2VRH6@28216|Betaproteobacteria,1K1XG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS3_k127_4805911_30	338966.Ppro_1236	1.851e-11	75.0	COG0810@1|root,COG0810@2|Bacteria,1QX76@1224|Proteobacteria,42V4D@68525|delta/epsilon subdivisions,2WRH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	mxcH	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
GDHHQS3_k127_4805911_15	483219.LILAB_25845	1.908e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,439N8@68525|delta/epsilon subdivisions,2X4ZH@28221|Deltaproteobacteria,2YZW4@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
GDHHQS3_k127_4805911_1	1089547.KB913013_gene2767	5.869e-213	674.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_4805911_31	946483.Cenrod_0718	2.365e-09	59.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,2W4E3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4805911_23	234267.Acid_4174	3.504e-33	145.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_4805911_11	485913.Krac_4939	5.215e-74	257.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_4805911_10	156889.Mmc1_1537	1.108e-79	286.0	COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,1R7VB@1224|Proteobacteria,2U5ZR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
GDHHQS3_k127_4805911_25	1442599.JAAN01000030_gene2061	9.651e-31	129.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,1SUF1@1236|Gammaproteobacteria,1X4RG@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25
GDHHQS3_k127_4805911_16	765420.OSCT_0569	3.026e-55	213.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi,3755I@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GDHHQS3_k127_4805911_22	1232410.KI421426_gene1402	9.511e-36	143.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions,2WPRH@28221|Deltaproteobacteria,43SJK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_4805911_0	1254432.SCE1572_10845	4.486e-236	746.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GDHHQS3_k127_4805911_20	290318.Cvib_0207	4.657e-38	165.0	COG1121@1|root,COG1121@2|Bacteria,1FEP4@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter related	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
GDHHQS3_k127_4805911_21	765912.Thimo_0040	2.395e-37	164.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1WX5H@135613|Chromatiales	135613|Chromatiales	P	pfam abc-3	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
GDHHQS3_k127_4805911_17	582515.KR51_00032700	2.36e-46	194.0	COG4222@1|root,COG4222@2|Bacteria,1G21P@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
GDHHQS3_k127_4805911_7	1089551.KE386572_gene3618	8.6e-100	365.0	COG0737@1|root,COG2374@1|root,COG3391@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,2TX32@28211|Alphaproteobacteria,4BR8C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C
GDHHQS3_k127_4805911_19	1047013.AQSP01000106_gene1773	6.365e-41	169.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
GDHHQS3_k127_4805911_18	234267.Acid_5730	7.959e-44	162.0	COG1695@1|root,COG1695@2|Bacteria,3Y5BK@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_4805911_2	1267535.KB906767_gene3695	7.369e-198	647.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4805911_3	96561.Dole_1208	3.561e-160	516.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,42NVM@68525|delta/epsilon subdivisions,2WJHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_3
GDHHQS3_k127_4805911_29	861299.J421_0735	1.353e-13	78.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0735|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	-
GDHHQS3_k127_4834293_3	1300345.LF41_1842	1.784e-104	370.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_4834293_6	1267535.KB906767_gene5001	3.086e-59	237.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GDHHQS3_k127_4834293_0	1379698.RBG1_1C00001G0797	1.596e-141	479.0	COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS3_k127_4834293_1	1379698.RBG1_1C00001G0607	4.648e-138	469.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_4834293_2	234267.Acid_4535	1.619e-109	402.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_4834293_4	234267.Acid_4535	3.288e-89	329.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_4834293_7	1122603.ATVI01000005_gene3430	3.1e-08	57.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,1T11U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_4834293_8	631362.Thi970DRAFT_04766	5.374e-08	61.0	COG1848@1|root,COG1848@2|Bacteria,1Q9A8@1224|Proteobacteria,1SPBZ@1236|Gammaproteobacteria,1X0SZ@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_4834293_5	234267.Acid_4535	9.201e-60	218.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_4838569_7	290397.Adeh_3025	1.346e-75	267.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_4838569_10	234267.Acid_7870	1.422e-39	168.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase A domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
GDHHQS3_k127_4838569_8	243231.GSU0456	2.507e-74	284.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,430XH@68525|delta/epsilon subdivisions,2WW53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein export membrane protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
GDHHQS3_k127_4838569_11	635013.TherJR_1434	7.287e-34	150.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,261MJ@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_4838569_9	1121468.AUBR01000016_gene2351	1.476e-40	158.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
GDHHQS3_k127_4838569_0	644282.Deba_1140	2.252e-248	797.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS3_k127_4838569_16	247156.NFA_38410	5.807e-11	70.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4G0EH@85025|Nocardiaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
GDHHQS3_k127_4838569_2	903818.KI912268_gene1402	3.021e-166	531.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_4838569_3	867845.KI911784_gene2151	9.01e-121	396.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_4838569_15	1123487.KB892868_gene1297	1.091e-22	115.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,2KW6H@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GDHHQS3_k127_4838569_13	1297617.JPJD01000072_gene1808	3.36e-24	113.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,2686P@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS3_k127_4838569_4	1121430.JMLG01000001_gene2279	1.795e-108	363.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_4838569_1	324602.Caur_2074	5.437e-213	689.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,3755N@32061|Chloroflexia	32061|Chloroflexia	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_4838569_12	1120973.AQXL01000075_gene966	4.907e-33	139.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,278G9@186823|Alicyclobacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS3_k127_4838569_6	338963.Pcar_0109	1.122e-75	267.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43S42@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	HrcA protein C terminal domain	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
GDHHQS3_k127_4838569_14	1210045.ALNP01000033_gene2528	3.884e-24	115.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GDHHQS3_k127_4838569_5	1121920.AUAU01000004_gene908	8.838e-84	288.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
GDHHQS3_k127_4992618_0	1245471.PCA10_48090	3.786e-98	333.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1YDFM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Sulfate permease family	dauA_1	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
GDHHQS3_k127_4992618_1	1047013.AQSP01000078_gene2052	2.458e-58	216.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
GDHHQS3_k127_5033453_0	861299.J421_5672	0.0	1249.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Glyco_hydro_63
GDHHQS3_k127_5033453_55	349965.yinte0001_38410	4.133e-30	124.0	COG1335@1|root,COG1335@2|Bacteria,1RARV@1224|Proteobacteria,1S2GI@1236|Gammaproteobacteria,41F8N@629|Yersinia	1236|Gammaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS3_k127_5033453_7	1379698.RBG1_1C00001G0607	2.638e-145	489.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_5033453_25	1121127.JAFA01000033_gene4520	9.216e-68	242.0	COG1028@1|root,COG1028@2|Bacteria,1PP5H@1224|Proteobacteria,2VJ4Y@28216|Betaproteobacteria,1K544@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_5033453_53	1384054.N790_13720	1.42e-30	141.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,1X7PC@135614|Xanthomonadales	135614|Xanthomonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_5033453_39	1160137.KB907307_gene3164	3.34e-51	198.0	COG1073@1|root,COG1073@2|Bacteria,2IA0F@201174|Actinobacteria,4FUH3@85025|Nocardiaceae	201174|Actinobacteria	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS3_k127_5033453_50	626887.J057_11741	1.656e-34	146.0	COG5504@1|root,COG5504@2|Bacteria,1RG9M@1224|Proteobacteria,1S2XI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
GDHHQS3_k127_5033453_22	1340493.JNIF01000004_gene863	2.017e-71	276.0	COG3386@1|root,COG3386@2|Bacteria,3Y5XH@57723|Acidobacteria	57723|Acidobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS3_k127_5033453_5	861299.J421_1876	2.36e-150	526.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
GDHHQS3_k127_5033453_32	861299.J421_1875	8.163e-59	223.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
GDHHQS3_k127_5033453_54	1415756.JQMY01000001_gene2031	1.425e-30	130.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_5033453_11	118161.KB235922_gene2998	1.13e-104	351.0	COG1028@1|root,COG1028@2|Bacteria,1G0IE@1117|Cyanobacteria	1117|Cyanobacteria	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_5033453_73	467661.RKLH11_3319	2.007e-07	58.0	28YR6@1|root,2ZKIN@2|Bacteria,1P8ED@1224|Proteobacteria,2UY0M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_5033453_34	314230.DSM3645_06149	3.189e-56	203.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5033453_40	1173264.KI913949_gene3511	7.836e-46	186.0	COG3350@1|root,COG3350@2|Bacteria,1G6RV@1117|Cyanobacteria,1HBTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Yhs domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_5033453_44	671143.DAMO_1116	4.292e-42	168.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS3_k127_5033453_65	351627.Csac_1897	6.094e-19	101.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,42GDW@68295|Thermoanaerobacterales	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
GDHHQS3_k127_5033453_10	518766.Rmar_0950	3.096e-116	397.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1FJVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS3_k127_5033453_16	1297742.A176_02095	1.497e-85	306.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
GDHHQS3_k127_5033453_38	479434.Sthe_0216	7.23e-52	199.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,27XMI@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	-	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_5033453_17	309807.SRU_2217	2.099e-84	294.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_5033453_23	518766.Rmar_0946	4.779e-70	263.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1FJUC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_5033453_24	1144275.COCOR_02389	5.325e-69	259.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_5033453_36	1121920.AUAU01000010_gene45	1.393e-53	203.0	COG0624@1|root,COG0624@2|Bacteria,3Y7TX@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_5033453_15	448385.sce1759	1.431e-85	303.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
GDHHQS3_k127_5033453_18	1379270.AUXF01000007_gene997	7.382e-83	308.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GDHHQS3_k127_5033453_76	1120934.KB894405_gene5341	0.0008533	51.0	COG1051@1|root,COG1051@2|Bacteria,2I2YK@201174|Actinobacteria,4E65Q@85010|Pseudonocardiales	201174|Actinobacteria	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_5033453_47	1519464.HY22_11745	9.297e-37	146.0	COG0457@1|root,COG0457@2|Bacteria	1519464.HY22_11745|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_27	1250005.PHEL85_1346	3.083e-66	236.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GDHHQS3_k127_5033453_33	1121920.AUAU01000006_gene301	2.275e-57	206.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_35	1265505.ATUG01000002_gene1088	1.342e-54	201.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_5033453_19	204669.Acid345_0678	8.793e-81	286.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yagE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_5033453_3	1122176.KB903542_gene336	2.475e-162	529.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS3_k127_5033453_58	1267533.KB906738_gene2200	5.002e-28	132.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS3_k127_5033453_13	1125863.JAFN01000001_gene1060	1.452e-87	317.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_5033453_71	1380390.JIAT01000009_gene617	2.955e-12	76.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4CQKQ@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS3_k127_5033453_14	1122604.JONR01000014_gene261	1.777e-87	297.0	COG0500@1|root,COG2226@2|Bacteria,1R7IA@1224|Proteobacteria,1SIK7@1236|Gammaproteobacteria,1X5T5@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_5033453_68	290397.Adeh_2759	6.905e-14	81.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS3_k127_5033453_46	1267535.KB906767_gene5001	9.762e-39	165.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GDHHQS3_k127_5033453_60	639030.JHVA01000001_gene2462	9.029e-26	125.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_1	452637.Oter_1890	0.0	1051.0	COG0577@1|root,COG0577@2|Bacteria,46UZM@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5033453_9	379066.GAU_2194	1.242e-133	434.0	COG0412@1|root,COG0412@2|Bacteria,1ZUKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_5033453_12	58123.JOFJ01000004_gene1873	1.665e-88	300.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EHBQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_5033453_37	1267535.KB906767_gene5244	5.631e-52	210.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
GDHHQS3_k127_5033453_26	1449351.RISW2_13285	1.292e-67	246.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria,4KK9X@93682|Roseivivax	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_5033453_31	584708.Apau_0957	1.925e-60	216.0	COG2859@1|root,COG2859@2|Bacteria,3TB3A@508458|Synergistetes	508458|Synergistetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_5033453_6	926569.ANT_05730	7.428e-147	479.0	COG2233@1|root,COG2233@2|Bacteria,2G8VZ@200795|Chloroflexi	200795|Chloroflexi	F	Permease family	-	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
GDHHQS3_k127_5033453_52	1150626.PHAMO_30061	4.359e-31	132.0	COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,2TUD0@28211|Alphaproteobacteria,2JU7A@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
GDHHQS3_k127_5033453_70	378806.STAUR_0671	3.734e-13	82.0	COG1285@1|root,COG1285@2|Bacteria,1RAIG@1224|Proteobacteria,42T1T@68525|delta/epsilon subdivisions,2WPMM@28221|Deltaproteobacteria,2YW34@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
GDHHQS3_k127_5033453_48	1267534.KB906759_gene1703	6.199e-36	150.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_51	1267535.KB906767_gene1002	4.256e-31	132.0	COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria	57723|Acidobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
GDHHQS3_k127_5033453_43	1161401.ASJA01000001_gene322	6.611e-43	164.0	COG0457@1|root,COG0457@2|Bacteria	1161401.ASJA01000001_gene322|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_2	452637.Oter_1995	4.122e-172	574.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5033453_66	936573.HMPREF1147_1056	5.38e-16	91.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H1W6@909932|Negativicutes	909932|Negativicutes	S	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
GDHHQS3_k127_5033453_41	1121918.ARWE01000001_gene793	2.815e-43	168.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GDHHQS3_k127_5033453_59	1089550.ATTH01000001_gene1048	1.305e-27	117.0	COG1846@1|root,COG1846@2|Bacteria,4PK2X@976|Bacteroidetes,1FJN7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
GDHHQS3_k127_5033453_28	1278073.MYSTI_04534	7.947e-66	234.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GDHHQS3_k127_5033453_57	649638.Trad_1325	4.394e-28	123.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	rsmD	-	2.1.1.171	ko:K08316,ko:K15257	-	-	R07234	RC00003	ko00000,ko01000,ko03009,ko03016	-	-	-	Cons_hypoth95
GDHHQS3_k127_5033453_63	861299.J421_1914	4.289e-25	107.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_5033453_8	1246995.AFR_17080	1.816e-134	452.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GDHHQS3_k127_5033453_30	1120999.JONM01000007_gene1748	1.614e-60	213.0	COG3832@1|root,COG3832@2|Bacteria,1RDXJ@1224|Proteobacteria,2WFS3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_5033453_42	614083.AWQR01000040_gene769	2.856e-43	162.0	COG0640@1|root,COG0640@2|Bacteria,1RIJ9@1224|Proteobacteria,2VTID@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS3_k127_5033453_29	1340493.JNIF01000003_gene2205	1.54e-60	212.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_5033453_67	1173023.KE650771_gene1772	1.109e-14	77.0	2C6B2@1|root,335GA@2|Bacteria,1G9BT@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_64	519989.ECTPHS_13833	6.992e-23	103.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,1WZD8@135613|Chromatiales	135613|Chromatiales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS3_k127_5033453_62	861299.J421_1914	1.66e-25	108.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_5033453_20	329726.AM1_5706	4.449e-77	267.0	COG0500@1|root,COG0500@2|Bacteria,1G4ZC@1117|Cyanobacteria	1117|Cyanobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_5033453_45	861299.J421_1785	1.054e-40	153.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_5033453_4	861299.J421_0393	3.91e-151	515.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0393|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_61	316067.Geob_2074	1.335e-25	111.0	COG1569@1|root,COG1569@2|Bacteria,1QSUM@1224|Proteobacteria,42WJR@68525|delta/epsilon subdivisions,2WRT9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_5033453_75	643648.Slip_1602	1.995e-05	55.0	COG4118@1|root,COG4118@2|Bacteria,1UQTX@1239|Firmicutes,258K8@186801|Clostridia,42KVV@68298|Syntrophomonadaceae	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_5033453_56	118163.Ple7327_4057	1.236e-28	123.0	COG2885@1|root,COG2885@2|Bacteria,1G7KW@1117|Cyanobacteria,3VMR8@52604|Pleurocapsales	1117|Cyanobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS3_k127_5033453_21	1382359.JIAL01000001_gene1135	4.754e-75	271.0	COG2227@1|root,COG2227@2|Bacteria,3Y9AQ@57723|Acidobacteria	57723|Acidobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5033453_49	1499967.BAYZ01000090_gene4936	4.269e-35	149.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_5033453_72	1380391.JIAS01000014_gene2015	1.139e-07	62.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2TU9N@28211|Alphaproteobacteria,2JSM5@204441|Rhodospirillales	204441|Rhodospirillales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
GDHHQS3_k127_5069932_0	1244869.H261_07853	4.108e-07	63.0	COG0500@1|root,COG2226@2|Bacteria,1QWJE@1224|Proteobacteria,2U37M@28211|Alphaproteobacteria,2JZFF@204441|Rhodospirillales	204441|Rhodospirillales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_5069932_1	497964.CfE428DRAFT_3275	3.794e-05	56.0	COG4083@1|root,COG4083@2|Bacteria,46WYA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
GDHHQS3_k127_5078366_0	204669.Acid345_4392	1.525e-112	389.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_5087134_2	1121438.JNJA01000002_gene3482	3.92e-61	221.0	COG1219@1|root,COG1219@2|Bacteria,1NS53@1224|Proteobacteria,42YDC@68525|delta/epsilon subdivisions,2WU6T@28221|Deltaproteobacteria,2MAA0@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2
GDHHQS3_k127_5087134_0	1242864.D187_009241	6.869e-143	497.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions,2WVIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_5087134_1	1304883.KI912532_gene1605	1.029e-64	236.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,2KVSB@206389|Rhodocyclales	206389|Rhodocyclales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5087134_3	1121920.AUAU01000011_gene187	6.176e-58	217.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0017	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5087134_4	1121920.AUAU01000024_gene2366	1.885e-09	68.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
GDHHQS3_k127_5155896_6	383372.Rcas_2506	7.573e-06	59.0	COG1287@1|root,COG1287@2|Bacteria,2GAA0@200795|Chloroflexi,376PD@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5155896_1	1032480.MLP_27670	1.464e-158	509.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
GDHHQS3_k127_5155896_3	861299.J421_0426	2.927e-138	469.0	COG0458@1|root,COG0458@2|Bacteria,1ZTAX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp
GDHHQS3_k127_5155896_2	1032480.MLP_27670	1.313e-142	464.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
GDHHQS3_k127_5155896_5	443144.GM21_1931	2.65e-65	250.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
GDHHQS3_k127_5155896_4	1111069.TCCBUS3UF1_21000	1.268e-105	367.0	COG1543@1|root,COG1543@2|Bacteria,1WIRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	hydrolase family 57	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
GDHHQS3_k127_5155896_0	1382306.JNIM01000001_gene1323	8.302e-210	678.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS3_k127_5157492_7	1254432.SCE1572_04585	3.448e-13	74.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
GDHHQS3_k127_5157492_2	1123401.JHYQ01000012_gene2956	5.63e-64	232.0	COG0834@1|root,COG0834@2|Bacteria,1P18B@1224|Proteobacteria,1T0T9@1236|Gammaproteobacteria,463D0@72273|Thiotrichales	72273|Thiotrichales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SBP_bac_3
GDHHQS3_k127_5157492_1	1242864.D187_006507	3.442e-147	489.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria,42Z41@68525|delta/epsilon subdivisions,2WU9F@28221|Deltaproteobacteria,2YUT7@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS3_k127_5157492_8	1089550.ATTH01000001_gene1633	2.123e-06	59.0	2EDTI@1|root,337NU@2|Bacteria,4P32V@976|Bacteroidetes,1FK0A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5157492_9	1121468.AUBR01000039_gene1926	0.000115	54.0	COG1842@1|root,COG1842@2|Bacteria,1V4Z3@1239|Firmicutes,25DDD@186801|Clostridia	186801|Clostridia	KT	Phage shock protein A (IM30), suppresses sigma54-dependent	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
GDHHQS3_k127_5157492_0	1163407.UU7_09065	6.911e-160	521.0	COG1231@1|root,COG1231@2|Bacteria,1RA9M@1224|Proteobacteria,1S3DF@1236|Gammaproteobacteria,1XCPQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_5157492_4	240016.ABIZ01000001_gene3377	7.614e-30	131.0	COG1011@1|root,COG1011@2|Bacteria,46T57@74201|Verrucomicrobia,2IUUA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_5157492_5	1200567.JNKD01000002_gene2228	1.787e-16	93.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1Y3VM@135624|Aeromonadales	135624|Aeromonadales	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_5157492_6	1089553.Tph_c16510	2.068e-13	83.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GDHHQS3_k127_5157492_10	631362.Thi970DRAFT_04153	0.00069	52.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WVXQ@135613|Chromatiales	135613|Chromatiales	O	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_5287356_13	240292.Ava_2004	0.0005888	50.0	COG0457@1|root,COG0457@2|Bacteria,1G31N@1117|Cyanobacteria,1HIXS@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS3_k127_5287356_1	1123242.JH636434_gene3744	9.762e-161	525.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_5287356_11	1123073.KB899241_gene2400	4.642e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5287356_6	485913.Krac_2433	1.759e-63	224.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_5287356_10	649638.Trad_1144	9.84e-25	111.0	COG1309@1|root,COG1309@2|Bacteria,1WI7P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
GDHHQS3_k127_5287356_9	682795.AciX8_3374	1.208e-28	132.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_5287356_2	84531.JMTZ01000070_gene1816	1.315e-155	498.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS3_k127_5287356_3	1122604.JONR01000020_gene495	3.804e-88	312.0	COG1357@1|root,COG2041@1|root,COG1357@2|Bacteria,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,1SD7X@1236|Gammaproteobacteria,1XB3F@135614|Xanthomonadales	135614|Xanthomonadales	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb,Pentapeptide
GDHHQS3_k127_5287356_7	290397.Adeh_3441	4.632e-35	154.0	COG3386@1|root,COG3386@2|Bacteria,1QYGK@1224|Proteobacteria,437EJ@68525|delta/epsilon subdivisions,2X2KV@28221|Deltaproteobacteria,2Z04K@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5287356_5	1415779.JOMH01000001_gene2547	3.036e-73	273.0	2E1MA@1|root,32WYJ@2|Bacteria,1N6KY@1224|Proteobacteria,1SBEM@1236|Gammaproteobacteria,1X9S8@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5287356_0	335543.Sfum_0263	0.0	1228.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MQ8A@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_5287356_4	743299.Acife_3105	1.065e-79	286.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,2NCG9@225057|Acidithiobacillales	225057|Acidithiobacillales	O	DnaJ C terminal domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS3_k127_5287356_8	670487.Ocepr_0464	3.953e-33	130.0	COG1146@1|root,COG1146@2|Bacteria,1WKCK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
GDHHQS3_k127_5287356_12	1089550.ATTH01000001_gene1118	4.723e-20	91.0	COG5394@1|root,COG5394@2|Bacteria,4PF5Z@976|Bacteroidetes,1FK70@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
GDHHQS3_k127_5350928_19	1049564.TevJSym_be00110	1.324e-82	278.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1J4F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS3_k127_5350928_32	1267533.KB906734_gene4347	4.684e-49	188.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS3_k127_5350928_9	1384056.N787_13695	1.773e-133	442.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X5QJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_5350928_27	1232410.KI421413_gene960	4.724e-68	257.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS3_k127_5350928_60	75379.Tint_2969	8.347e-07	61.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,1KKQB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GDHHQS3_k127_5350928_7	234267.Acid_3811	2.719e-156	507.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria	57723|Acidobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_5350928_52	335543.Sfum_2591	8.345e-18	95.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MQK3@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS3_k127_5350928_10	1047013.AQSP01000071_gene1933	4.275e-132	445.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
GDHHQS3_k127_5350928_24	457398.HMPREF0326_00452	5.196e-73	263.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2M7YK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_5350928_8	1499967.BAYZ01000029_gene1223	1.588e-145	478.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
GDHHQS3_k127_5350928_67	1035197.HMPREF9999_02293	0.000358	55.0	COG1216@1|root,COG3642@1|root,COG1216@2|Bacteria,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,2FPB2@200643|Bacteroidia	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Kdo
GDHHQS3_k127_5350928_28	1047013.AQSP01000139_gene2354	6.258e-61	243.0	COG3642@1|root,COG3642@2|Bacteria	2|Bacteria	T	kinase activity	rfaY	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	ko:K02850	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Kdo,WaaY
GDHHQS3_k127_5350928_39	861299.J421_0114	1.696e-40	158.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_5350928_34	316274.Haur_4485	1.792e-45	191.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_5350928_53	861299.J421_1214	8.72e-18	90.0	COG1595@1|root,COG1595@2|Bacteria,1ZV5F@142182|Gemmatimonadetes	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PD40,PQQ_2,Sigma70_r2,Sigma70_r4_2,WD40
GDHHQS3_k127_5350928_56	118166.JH976538_gene5193	5.768e-16	93.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
GDHHQS3_k127_5350928_5	234267.Acid_7369	2.301e-188	604.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_5350928_16	215803.DB30_1187	4.808e-91	315.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria,2YZ41@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_5350928_22	391625.PPSIR1_11110	2.716e-74	265.0	COG2988@1|root,COG2988@2|Bacteria	2|Bacteria	E	succinylglutamate desuccinylase activity	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
GDHHQS3_k127_5350928_47	595460.RRSWK_05276	2.59e-28	127.0	COG0584@1|root,COG0584@2|Bacteria,2J0S0@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb,HEAT_2
GDHHQS3_k127_5350928_65	1382359.JIAL01000001_gene2857	0.0001312	50.0	2CBGA@1|root,32RQS@2|Bacteria,3Y586@57723|Acidobacteria,2JJU2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5350928_45	1157490.EL26_09460	8.865e-35	148.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27891@186823|Alicyclobacillaceae	91061|Bacilli	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_5350928_33	1047013.AQSP01000132_gene1706	7.7e-47	179.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GDHHQS3_k127_5350928_14	1047013.AQSP01000132_gene1707	9.494e-99	349.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
GDHHQS3_k127_5350928_54	439235.Dalk_3109	1.213e-17	95.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria,42XQS@68525|delta/epsilon subdivisions,2WTAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
GDHHQS3_k127_5350928_40	566466.NOR53_2748	3.588e-38	154.0	COG3568@1|root,COG3568@2|Bacteria,1RJZP@1224|Proteobacteria,1TH72@1236|Gammaproteobacteria,1JABN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS3_k127_5350928_44	644966.Tmar_0760	3.12e-36	142.0	COG2947@1|root,COG2947@2|Bacteria,1V45I@1239|Firmicutes,24P4G@186801|Clostridia	186801|Clostridia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GDHHQS3_k127_5350928_62	301.JNHE01000020_gene3962	2.879e-06	61.0	COG2823@1|root,COG2823@2|Bacteria,1RHX0@1224|Proteobacteria,1S742@1236|Gammaproteobacteria,1YIS5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS3_k127_5350928_13	555079.Toce_1473	3.167e-112	378.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_5350928_55	760568.Desku_0177	1.605e-16	91.0	COG2253@1|root,COG2253@2|Bacteria,1UKDE@1239|Firmicutes,25FUI@186801|Clostridia,267DM@186807|Peptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_5350928_57	1196323.ALKF01000168_gene522	2.15e-15	83.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,26R1N@186822|Paenibacillaceae	91061|Bacilli	D	Septum formation initiator	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
GDHHQS3_k127_5350928_58	667014.Thein_1772	3.835e-14	87.0	COG0762@1|root,COG0762@2|Bacteria,2GHYF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS3_k127_5350928_0	204669.Acid345_3507	1.917e-312	977.0	COG0567@1|root,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria,2JICX@204432|Acidobacteriia	204432|Acidobacteriia	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoGdeHyase_C,Transket_pyr
GDHHQS3_k127_5350928_12	502025.Hoch_5836	9.834e-123	409.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YXC1@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS3_k127_5350928_20	1329516.JPST01000003_gene1164	7.471e-78	279.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HABY@91061|Bacilli,27CM5@186824|Thermoactinomycetaceae	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
GDHHQS3_k127_5350928_21	644966.Tmar_0709	2.291e-77	276.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCDT@538999|Clostridiales incertae sedis	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_5350928_15	997346.HMPREF9374_2151	6.701e-96	343.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS3_k127_5350928_18	1379270.AUXF01000002_gene1761	3.267e-85	317.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5350928_61	1121091.AUMP01000054_gene3367	1.178e-06	56.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5350928_6	2002.JOEQ01000007_gene2031	2.618e-174	556.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4EI3R@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS3_k127_5350928_43	113395.AXAI01000014_gene218	1.427e-37	148.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,3K009@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,Cupin_7,DUF4437
GDHHQS3_k127_5350928_51	656024.FsymDg_3418	1.468e-22	102.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2H996@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS3_k127_5350928_35	883126.HMPREF9710_03605	7.39e-45	185.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,476RI@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GDHHQS3_k127_5350928_41	1297742.A176_03422	1.087e-37	163.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_5350928_36	404380.Gbem_0848	1.232e-41	171.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
GDHHQS3_k127_5350928_25	1323663.AROI01000004_gene2130	8.156e-70	258.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
GDHHQS3_k127_5350928_23	926566.Terro_3588	4.028e-73	265.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GDHHQS3_k127_5350928_3	204669.Acid345_1576	6.891e-218	689.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GDHHQS3_k127_5350928_63	234267.Acid_0046	3.577e-05	55.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria	57723|Acidobacteria	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GDHHQS3_k127_5350928_59	1232410.KI421421_gene3653	2.661e-07	63.0	2DXN2@1|root,345N1@2|Bacteria,1Q1PJ@1224|Proteobacteria,4319I@68525|delta/epsilon subdivisions,2WWAH@28221|Deltaproteobacteria,43VEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pilus assembly protein, PilO	pulO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GDHHQS3_k127_5350928_17	1047013.AQSP01000036_gene1385	6.155e-90	326.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
GDHHQS3_k127_5350928_42	639030.JHVA01000001_gene638	1.294e-37	158.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GDHHQS3_k127_5350928_48	1123368.AUIS01000016_gene2544	4.653e-26	122.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,1S8T4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
GDHHQS3_k127_5350928_31	384765.SIAM614_27917	3.475e-50	191.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
GDHHQS3_k127_5350928_30	342113.DM82_88	1.271e-51	196.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,1K14B@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GDHHQS3_k127_5350928_29	671143.DAMO_2311	4.244e-58	209.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
GDHHQS3_k127_5350928_49	68223.JNZY01000008_gene2871	1.397e-24	110.0	2EIR7@1|root,33CGM@2|Bacteria,2IQ40@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_5350928_2	1125863.JAFN01000001_gene1578	4.053e-256	824.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
GDHHQS3_k127_5350928_4	314230.DSM3645_17370	1.642e-192	614.0	COG0008@1|root,COG0008@2|Bacteria,2IXD6@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS3_k127_5350928_11	1123277.KB893187_gene2734	2.179e-126	425.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,47NUP@768503|Cytophagia	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
GDHHQS3_k127_5350928_26	981384.AEYW01000018_gene3160	2.75e-69	259.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TQXY@28211|Alphaproteobacteria,4NDRU@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
GDHHQS3_k127_5350928_1	1125863.JAFN01000001_gene1711	2.037e-260	822.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GDHHQS3_k127_5350928_37	518766.Rmar_0610	3.291e-41	171.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_5350928_38	518766.Rmar_0611	9.052e-41	160.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_5350928_64	1168059.KB899087_gene1061	4.21e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_5350928_46	398525.KB900701_gene4059	3.529e-29	136.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,3JUT7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Bacterial type II and III secretion system protein	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
GDHHQS3_k127_5350928_66	526225.Gobs_4272	0.0003182	51.0	COG1261@1|root,COG1261@2|Bacteria,2GR8T@201174|Actinobacteria,4EXDF@85013|Frankiales	201174|Actinobacteria	NO	PFAM SAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
GDHHQS3_k127_5350928_50	1168065.DOK_06335	1.421e-22	101.0	2E76C@1|root,331QA@2|Bacteria,1NFDI@1224|Proteobacteria,1SDAY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_28	671143.DAMO_2425	5.049e-57	216.0	COG0388@1|root,COG0388@2|Bacteria,2NQD8@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GDHHQS3_k127_5418416_47	682795.AciX8_0646	1.198e-08	66.0	COG0760@1|root,COG0760@2|Bacteria,3Y4KY@57723|Acidobacteria,2JJDJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
GDHHQS3_k127_5418416_8	671143.DAMO_0704	1.027e-116	389.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_5418416_36	1449355.JQNR01000004_gene1287	4.05e-42	168.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_5418416_0	1144275.COCOR_05001	0.0	1223.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,2YUNJ@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
GDHHQS3_k127_5418416_25	287.DR97_2274	8.964e-66	230.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria,1YDY7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_5418416_50	330084.JNYZ01000005_gene924	0.0001038	55.0	COG2755@1|root,COG2755@2|Bacteria,2GP5V@201174|Actinobacteria,4E2U7@85010|Pseudonocardiales	201174|Actinobacteria	E	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,VCBS
GDHHQS3_k127_5418416_52	1411123.JQNH01000001_gene490	0.0003632	54.0	arCOG14225@1|root,2ZC7S@2|Bacteria,1RA98@1224|Proteobacteria,2U62Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GDHHQS3_k127_5418416_13	648996.Theam_1729	1.369e-97	344.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS3_k127_5418416_31	1307759.JOMJ01000003_gene1221	1.713e-50	193.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,43B4R@68525|delta/epsilon subdivisions,2X5VN@28221|Deltaproteobacteria,2MGWB@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_5418416_35	1121033.AUCF01000003_gene3255	2.776e-42	180.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,2JPU9@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_5418416_23	1120973.AQXL01000083_gene2911	1.242e-70	259.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,279UI@186823|Alicyclobacillaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_5418416_39	1379698.RBG1_1C00001G1442	4.37e-36	142.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS3_k127_5418416_40	1297742.A176_00281	3.327e-33	145.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2YV02@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS3_k127_5418416_10	335541.Swol_1170	5.841e-113	379.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42JHI@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_5418416_41	330084.JNYZ01000001_gene3166	1.349e-21	106.0	COG2267@1|root,COG2267@2|Bacteria,2HN3N@201174|Actinobacteria,4E9WV@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GDHHQS3_k127_5418416_12	1163409.UUA_14289	5.682e-99	340.0	COG4874@1|root,COG4874@2|Bacteria,1N05R@1224|Proteobacteria,1S34T@1236|Gammaproteobacteria,1X5DC@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria containing a pentein-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
GDHHQS3_k127_5418416_37	1379270.AUXF01000003_gene3484	1.608e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5418416_32	523791.Kkor_1200	4.265e-47	180.0	29IKN@1|root,305HW@2|Bacteria,1RGDD@1224|Proteobacteria,1S5R7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_33	1384054.N790_05050	2.348e-44	177.0	COG1716@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,1NEF7@1224|Proteobacteria,1SEW5@1236|Gammaproteobacteria,1X6HU@135614|Xanthomonadales	135614|Xanthomonadales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2
GDHHQS3_k127_5418416_4	84531.JMTZ01000010_gene3183	7.22e-169	582.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1X4Y2@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
GDHHQS3_k127_5418416_26	1123261.AXDW01000017_gene3195	2.368e-61	221.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,1T1IF@1236|Gammaproteobacteria,1X6EA@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GDHHQS3_k127_5418416_17	84531.JMTZ01000010_gene3185	7.561e-78	268.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1X61F@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_5418416_3	1048834.TC41_0652	1.684e-195	631.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,2783I@186823|Alicyclobacillaceae	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS3_k127_5418416_22	631362.Thi970DRAFT_03022	3.175e-71	262.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1SX52@1236|Gammaproteobacteria,1X227@135613|Chromatiales	135613|Chromatiales	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C
GDHHQS3_k127_5418416_6	880073.Calab_3349	3.528e-149	494.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_2	401526.TcarDRAFT_1976	9.482e-201	646.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
GDHHQS3_k127_5418416_51	378806.STAUR_6212	0.0002268	55.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1QX6K@1224|Proteobacteria,43BZ6@68525|delta/epsilon subdivisions,2WRS2@28221|Deltaproteobacteria,2YTW4@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg,TPR_16,TPR_8
GDHHQS3_k127_5418416_7	906968.Trebr_1155	8.189e-120	400.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	rrp-2	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_5418416_24	1279009.ADICEAN_01094	3.216e-70	256.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47U3U@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
GDHHQS3_k127_5418416_14	1198114.AciX9_3050	3.094e-96	342.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_5418416_45	1121440.AUMA01000003_gene3146	1.389e-11	78.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS3_k127_5418416_29	123214.PERMA_1676	2.304e-54	220.0	COG1624@1|root,COG1624@2|Bacteria,2G3ZW@200783|Aquificae	200783|Aquificae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
GDHHQS3_k127_5418416_19	404589.Anae109_2337	3.405e-73	257.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
GDHHQS3_k127_5418416_1	1232410.KI421415_gene3040	9.454e-233	737.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,43S6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FtsH Extracellular	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS3_k127_5418416_34	555088.DealDRAFT_2465	1.854e-43	177.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42JX4@68298|Syntrophomonadaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GDHHQS3_k127_5418416_16	518766.Rmar_0920	2.485e-80	274.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1FJ6I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS3_k127_5418416_48	1313421.JHBV01000002_gene551	4.498e-07	53.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_42	637390.AFOH01000011_gene811	4.085e-16	81.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,2NDAG@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GDHHQS3_k127_5418416_21	880072.Desac_2063	2.188e-71	254.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS3_k127_5418416_11	204669.Acid345_2676	3.788e-108	369.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS3_k127_5418416_44	1340493.JNIF01000003_gene2257	2.815e-15	79.0	COG1826@1|root,COG1826@2|Bacteria,3Y5TY@57723|Acidobacteria	57723|Acidobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_5418416_30	204669.Acid345_2680	3.783e-52	200.0	COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS3_k127_5418416_15	1123023.JIAI01000004_gene7859	2.728e-82	306.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4E9Z4@85010|Pseudonocardiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_5418416_9	1120949.KB903294_gene4466	1.056e-114	407.0	COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4DC20@85008|Micromonosporales	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
GDHHQS3_k127_5418416_18	1050202.KB913024_gene1144	5.453e-76	270.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,408TH@622450|Actinopolysporales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_5418416_20	405948.SACE_2193	3.519e-72	269.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4E0AJ@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_5418416_5	118168.MC7420_1140	1.947e-151	516.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,1G2QW@1117|Cyanobacteria,1H8CY@1150|Oscillatoriales	1117|Cyanobacteria	CT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
GDHHQS3_k127_5418416_46	159087.Daro_1275	2.816e-11	77.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,2KUED@206389|Rhodocyclales	206389|Rhodocyclales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_5418416_43	1469607.KK073768_gene2207	1.183e-15	89.0	COG2850@1|root,COG2850@2|Bacteria	2|Bacteria	P	peptidyl-arginine hydroxylation	-	-	1.14.11.27	ko:K10277,ko:K19219	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	Cupin_8
GDHHQS3_k127_5418416_49	426355.Mrad2831_1348	3.601e-05	55.0	COG0454@1|root,COG0456@2|Bacteria,1R07B@1224|Proteobacteria,2TYM7@28211|Alphaproteobacteria,1JR5G@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_38	314285.KT71_11209	5.583e-38	161.0	2DCFR@1|root,2ZDYQ@2|Bacteria,1RB5X@1224|Proteobacteria,1RN4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5418416_27	861299.J421_4062	9.195e-58	224.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_5451219_9	861299.J421_1664	6.937e-42	170.0	2E0UX@1|root,32WC9@2|Bacteria,1ZUE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5451219_7	1278073.MYSTI_01100	1.396e-48	186.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GDHHQS3_k127_5451219_10	1278073.MYSTI_01136	9.727e-41	163.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WP0X@28221|Deltaproteobacteria,2YY9Z@29|Myxococcales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
GDHHQS3_k127_5451219_2	338963.Pcar_1943	7.789e-103	349.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43S6C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SIS domain	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
GDHHQS3_k127_5451219_11	234267.Acid_0506	3.143e-30	124.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GDHHQS3_k127_5451219_14	1184609.KILIM_092_00100	2.301e-05	49.0	2BRZD@1|root,32KZR@2|Bacteria,2HDNI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5451219_3	641491.DND132_0546	2.38e-78	287.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2M90H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GDHHQS3_k127_5451219_6	243233.MCA1000	4.282e-58	229.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
GDHHQS3_k127_5451219_0	1125863.JAFN01000001_gene910	8.809e-234	735.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
GDHHQS3_k127_5451219_5	574087.Acear_2185	2.503e-63	226.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GDHHQS3_k127_5451219_15	471853.Bcav_3681	3.063e-05	56.0	COG3408@1|root,COG3408@2|Bacteria,2IA19@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C
GDHHQS3_k127_5451219_4	234267.Acid_3351	1.502e-65	236.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_5451219_8	1048834.TC41_1409	8.336e-46	172.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,278D5@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GDHHQS3_k127_5451219_12	290397.Adeh_0088	1.12e-06	62.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2YVS1@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GDHHQS3_k127_5451219_1	401053.AciPR4_0954	2.917e-160	520.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS3_k127_5451219_16	1121378.KB899719_gene397	0.000207	52.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	GspH,N_methyl
GDHHQS3_k127_5550657_2	1121935.AQXX01000103_gene1351	5.163e-98	323.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XHPQ@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_5550657_0	1125863.JAFN01000001_gene2813	3.486e-220	709.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
GDHHQS3_k127_5550657_10	1349767.GJA_3140	2.753e-08	62.0	COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5550657_8	883126.HMPREF9710_04256	6.926e-34	140.0	COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5550657_4	1121920.AUAU01000002_gene2095	1.056e-74	264.0	COG2972@1|root,COG2972@2|Bacteria,3Y4BE@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
GDHHQS3_k127_5550657_3	204669.Acid345_3487	4.112e-75	261.0	COG3279@1|root,COG3279@2|Bacteria,3Y3B3@57723|Acidobacteria,2JP1W@204432|Acidobacteriia	204432|Acidobacteriia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS3_k127_5550657_9	204669.Acid345_1594	6.46e-24	114.0	COG0457@1|root,COG0457@2|Bacteria,3Y4VN@57723|Acidobacteria,2JJG5@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS3_k127_5550657_6	1121918.ARWE01000001_gene2756	6.938e-62	226.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,43T6F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_5550657_5	118166.JH976538_gene5057	3.119e-74	282.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
GDHHQS3_k127_5550657_7	1183438.GKIL_1929	1.037e-36	161.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS3_k127_5550657_1	251221.35211934	9.552e-200	627.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria	1117|Cyanobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_5634161_0	1187851.A33M_0966	3.962e-30	134.0	COG0438@1|root,COG0438@2|Bacteria,1MVT0@1224|Proteobacteria,2U2ZR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glycos_transf_1
GDHHQS3_k127_5634161_1	414684.RC1_4027	2.801e-12	68.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JW1S@204441|Rhodospirillales	204441|Rhodospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_5660453_1	767817.Desgi_0419	4.76e-118	391.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_5660453_2	391625.PPSIR1_15375	9.316e-06	59.0	2DPJ9@1|root,332BI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
GDHHQS3_k127_5660453_0	1313421.JHBV01000020_gene5292	7.43e-159	536.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1IWCK@117747|Sphingobacteriia	976|Bacteroidetes	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
GDHHQS3_k127_5660453_3	425104.Ssed_1748	0.0007293	49.0	2AJ20@1|root,319K9@2|Bacteria,1QFG0@1224|Proteobacteria,1TCQ9@1236|Gammaproteobacteria,2QDG3@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
GDHHQS3_k127_5730701_0	1122611.KB903977_gene2806	1.29e-222	700.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
GDHHQS3_k127_5730701_26	208439.AJAP_16960	8.996e-26	110.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
GDHHQS3_k127_5730701_12	1210884.HG799466_gene12383	9.428e-73	255.0	COG1526@1|root,COG1526@2|Bacteria,2IZ61@203682|Planctomycetes	203682|Planctomycetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
GDHHQS3_k127_5730701_17	290397.Adeh_2142	3.729e-59	222.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
GDHHQS3_k127_5730701_5	903818.KI912268_gene1011	1.351e-113	406.0	COG2199@1|root,COG3706@2|Bacteria,3Y3YU@57723|Acidobacteria	57723|Acidobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
GDHHQS3_k127_5730701_20	575540.Isop_0496	2.224e-51	196.0	COG0564@1|root,COG0564@2|Bacteria,2J01R@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_5730701_23	535289.Dtpsy_3128	1.647e-40	162.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VHHM@28216|Betaproteobacteria,4AEV1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS3_k127_5730701_1	1122134.KB893650_gene872	3.229e-208	681.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1N4G0@1224|Proteobacteria,1RRIM@1236|Gammaproteobacteria,1XRBX@135619|Oceanospirillales	135619|Oceanospirillales	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
GDHHQS3_k127_5730701_31	1246995.AFR_04005	1.132e-08	65.0	COG0346@1|root,COG0346@2|Bacteria,2GS59@201174|Actinobacteria,4DGI8@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
GDHHQS3_k127_5730701_3	1254432.SCE1572_17000	6.032e-119	392.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS3_k127_5730701_27	414996.IL38_06620	2.339e-23	117.0	COG0304@1|root,COG0304@2|Bacteria,2GNT4@201174|Actinobacteria,40AFR@622450|Actinopolysporales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_5730701_13	1463934.JOCF01000067_gene5211	4.55e-68	265.0	COG0304@1|root,COG0304@2|Bacteria,2GNT4@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.235,2.3.1.260	ko:K05551,ko:K09458	ko00061,ko00253,ko00780,ko01056,ko01100,ko01130,ko01212,map00061,map00253,map00780,map01056,map01100,map01130,map01212	M00083,M00572,M00778	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R06635,R06637,R06641,R06643,R06644,R06645,R07762,R09258,R09259,R10115,R10119,R10960,R11516	RC00004,RC00039,RC02545,RC02728,RC02729,RC02888,RC02931,RC02932,RC02947	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_5730701_14	497964.CfE428DRAFT_0942	1.685e-65	247.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
GDHHQS3_k127_5730701_22	497964.CfE428DRAFT_1495	6.066e-42	171.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_5730701_6	497964.CfE428DRAFT_0927	4.834e-99	344.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
GDHHQS3_k127_5730701_8	767817.Desgi_0471	7.866e-97	325.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GDHHQS3_k127_5730701_7	404589.Anae109_2774	1.875e-97	330.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_5730701_16	1051632.TPY_1473	5.669e-64	241.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GDHHQS3_k127_5730701_29	1246995.AFR_13975	6.365e-14	85.0	COG2340@1|root,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
GDHHQS3_k127_5730701_10	1300345.LF41_1473	1.698e-85	295.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RY2M@1236|Gammaproteobacteria,1X6IZ@135614|Xanthomonadales	135614|Xanthomonadales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,dCache_1
GDHHQS3_k127_5730701_32	1040986.ATYO01000055_gene2841	4.815e-07	61.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_5730701_25	929556.Solca_0474	3.198e-29	125.0	COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1IT5S@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_5730701_2	234267.Acid_4563	1.638e-125	415.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria	57723|Acidobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_5730701_24	1089545.KB913037_gene4160	3.913e-37	161.0	COG2049@1|root,COG2049@2|Bacteria,2I2R8@201174|Actinobacteria,4E32G@85010|Pseudonocardiales	201174|Actinobacteria	E	Allophanate hydrolase subunit 1	kipI	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
GDHHQS3_k127_5730701_19	1382315.JPOI01000001_gene2702	2.098e-51	199.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1WE6K@129337|Geobacillus	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
GDHHQS3_k127_5730701_21	292415.Tbd_2811	9.885e-47	186.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
GDHHQS3_k127_5730701_30	861299.J421_4363	2.66e-11	69.0	2ED24@1|root,336Z2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5730701_4	266117.Rxyl_0083	7.815e-114	377.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_5730701_9	479434.Sthe_3148	9.066e-94	322.0	COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi	200795|Chloroflexi	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5730701_11	1121920.AUAU01000013_gene1716	3.573e-79	280.0	COG4313@1|root,COG4313@2|Bacteria,3Y7K3@57723|Acidobacteria	57723|Acidobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5730701_15	583355.Caka_0239	1.017e-64	228.0	COG1321@1|root,COG1321@2|Bacteria,46T7C@74201|Verrucomicrobia,3K8J0@414999|Opitutae	414999|Opitutae	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_5730701_18	1047013.AQSP01000106_gene1773	6.966e-54	211.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
GDHHQS3_k127_5730701_28	1267534.KB906756_gene2	4.006e-20	94.0	COG0577@1|root,COG0577@2|Bacteria,3Y6GK@57723|Acidobacteria,2JKI5@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5817539_25	1254432.SCE1572_27875	2.018e-18	98.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36
GDHHQS3_k127_5817539_9	1123242.JH636435_gene2917	1.226e-82	301.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_5817539_19	1107311.Q767_11780	1.564e-45	175.0	2A9UH@1|root,30Z2C@2|Bacteria,4PD3Q@976|Bacteroidetes,1IDMI@117743|Flavobacteriia,2NYRQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5817539_27	398578.Daci_0446	2.875e-13	71.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,4A9KK@80864|Comamonadaceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GDHHQS3_k127_5817539_11	1318628.MARLIPOL_12500	1.447e-75	271.0	COG2982@1|root,COG2982@2|Bacteria,1NARH@1224|Proteobacteria,1SE5J@1236|Gammaproteobacteria,468PT@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
GDHHQS3_k127_5817539_6	1379698.RBG1_1C00001G0607	2.603e-123	423.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_5817539_7	1122179.KB890422_gene2225	2.464e-115	392.0	COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes	976|Bacteroidetes	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS3_k127_5817539_16	661478.OP10G_0362	2.605e-60	226.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,DUF4185
GDHHQS3_k127_5817539_32	1499967.BAYZ01000095_gene4224	0.0001225	49.0	COG1586@1|root,COG1586@2|Bacteria,2NQ5D@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	2.5.1.128,2.5.1.16,4.1.1.50	ko:K00797,ko:K01611,ko:K07057	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
GDHHQS3_k127_5817539_15	748247.AZKH_p0460	2.476e-65	227.0	COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,2VUPJ@28216|Betaproteobacteria,2KZHR@206389|Rhodocyclales	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS3_k127_5817539_24	366602.Caul_3841	1.777e-30	122.0	2CTS0@1|root,32SU1@2|Bacteria,1N10P@1224|Proteobacteria,2UU0S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5817539_4	1297569.MESS2_610021	3.019e-157	505.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2U28M@28211|Alphaproteobacteria,43QZ7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_5817539_21	153948.NAL212_2867	1.5e-34	141.0	COG0664@1|root,COG0664@2|Bacteria,1NFZP@1224|Proteobacteria,2WDER@28216|Betaproteobacteria,3743E@32003|Nitrosomonadales	28216|Betaproteobacteria	K	SMART HTH transcriptional regulator, Crp	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_5817539_30	266117.Rxyl_2616	3.175e-10	70.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4CSAC@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_5817539_18	671143.DAMO_1836	5.594e-48	192.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
GDHHQS3_k127_5817539_31	1125863.JAFN01000001_gene3521	0.0001103	55.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GDHHQS3_k127_5817539_12	338963.Pcar_2724	2.417e-73	267.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
GDHHQS3_k127_5817539_13	1229204.AMYY01000018_gene2187	9.688e-73	271.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,4BP7Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GDHHQS3_k127_5817539_17	349741.Amuc_1763	4.759e-51	189.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,2IU7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS3_k127_5817539_33	667014.Thein_0032	0.0002958	51.0	COG1579@1|root,COG1579@2|Bacteria,2GH3N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS3_k127_5817539_22	1304872.JAGC01000003_gene3670	4.697e-33	150.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2M9S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
GDHHQS3_k127_5817539_29	204669.Acid345_2692	6.288e-11	76.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5817539_28	1121920.AUAU01000013_gene1762	2.916e-13	83.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS3_k127_5817539_8	644966.Tmar_0840	8.003e-84	308.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3WCCA@538999|Clostridiales incertae sedis	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS3_k127_5817539_10	1125863.JAFN01000001_gene3288	3.895e-81	294.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS3_k127_5817539_5	204669.Acid345_4296	1.075e-156	513.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_5817539_26	378806.STAUR_0547	2.051e-14	81.0	2DQ35@1|root,334JG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GDHHQS3_k127_5817539_14	1120999.JONM01000004_gene3582	1.273e-65	233.0	COG1024@1|root,COG1024@2|Bacteria,1PKSD@1224|Proteobacteria,2W26S@28216|Betaproteobacteria,2KSWE@206351|Neisseriales	206351|Neisseriales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GDHHQS3_k127_5817539_20	266117.Rxyl_2043	1.273e-35	151.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS3_k127_5817539_2	518766.Rmar_2129	4.871e-207	655.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1FIWI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_5817539_1	945713.IALB_0301	6.789e-233	729.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_5817539_0	204669.Acid345_0280	1.069e-301	957.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,3Y7G5@57723|Acidobacteria	57723|Acidobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
GDHHQS3_k127_5817539_23	1234364.AMSF01000010_gene509	8.735e-31	142.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1RPC0@1236|Gammaproteobacteria,1X4RR@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS_4,PAS_9
GDHHQS3_k127_5817539_3	396588.Tgr7_1990	1.828e-160	541.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg
GDHHQS3_k127_5869433_0	1267535.KB906767_gene1458	4.185e-179	581.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS3_k127_5869433_6	1047013.AQSP01000078_gene2052	1.258e-59	231.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
GDHHQS3_k127_5869433_8	1340493.JNIF01000003_gene1505	3.211e-45	175.0	2F2X8@1|root,33VSU@2|Bacteria,3Y7XB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5869433_2	234267.Acid_7687	1.764e-115	394.0	COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5869433_7	234267.Acid_7688	8.34e-59	217.0	COG1277@1|root,COG1277@2|Bacteria,3Y839@57723|Acidobacteria	57723|Acidobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
GDHHQS3_k127_5869433_3	234267.Acid_7689	1.095e-102	362.0	COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5869433_4	1267534.KB906759_gene1816	1.599e-93	344.0	COG3712@1|root,COG3712@2|Bacteria,3Y772@57723|Acidobacteria	57723|Acidobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS3_k127_5869433_9	234267.Acid_7691	2.843e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_5869433_1	756272.Plabr_3346	1.285e-173	559.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
GDHHQS3_k127_5869433_5	290317.Cpha266_1510	1.337e-60	214.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GDHHQS3_k127_5886464_0	1123508.JH636442_gene4006	1.98e-119	401.0	COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes	203682|Planctomycetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_6137832_0	1158150.KB906246_gene1915	0.0	1384.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GDHHQS3_k127_6137832_1	713586.KB900536_gene1341	6.2e-159	509.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
GDHHQS3_k127_6137832_2	608538.HTH_1715	6.107e-29	128.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0001666,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0036293,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0050896,GO:0051131,GO:0065003,GO:0070482,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	1.7.5.1	ko:K00370,ko:K00373,ko:K17052	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,iYO844.BSU37260,ic_1306.c1687	Nitrate_red_del
GDHHQS3_k127_6137832_3	713586.KB900536_gene1339	3.257e-08	64.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
GDHHQS3_k127_61587_26	452637.Oter_3628	8.478e-51	185.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GDHHQS3_k127_61587_5	1120985.AUMI01000011_gene435	1.016e-133	435.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
GDHHQS3_k127_61587_41	1121957.ATVL01000012_gene650	1.108e-29	133.0	COG5266@1|root,COG5266@2|Bacteria,4NQ8X@976|Bacteroidetes,47QXS@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
GDHHQS3_k127_61587_10	945713.IALB_3049	3.064e-89	331.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
GDHHQS3_k127_61587_2	880073.Calab_3693	6.478e-174	569.0	COG1297@1|root,COG1297@2|Bacteria,2NPP0@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS3_k127_61587_54	1000565.METUNv1_03350	0.0006424	50.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VS6T@28216|Betaproteobacteria,2M01P@206389|Rhodocyclales	28216|Betaproteobacteria	M	OmpW family	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
GDHHQS3_k127_61587_4	240015.ACP_0820	7.792e-149	492.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria,2JHTA@204432|Acidobacteriia	204432|Acidobacteriia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_61587_3	94122.Shewana3_1461	6.01e-155	537.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,2Q8NI@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities	fadJ	GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886	3HCDH,3HCDH_N,ECH_1
GDHHQS3_k127_61587_46	278963.ATWD01000001_gene1886	1.78e-21	111.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_61587_20	1254432.SCE1572_37210	6.778e-62	222.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GDHHQS3_k127_61587_52	405948.SACE_7208	2.093e-08	63.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DYUX@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_61587_44	1297742.A176_00377	2.179e-22	113.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_61587_45	62928.azo0926	4.903e-22	108.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,2KWMY@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GDHHQS3_k127_61587_49	269799.Gmet_0176	1.041e-17	95.0	2DE9Y@1|root,2ZM4N@2|Bacteria,1Q17X@1224|Proteobacteria,43756@68525|delta/epsilon subdivisions,2X21C@28221|Deltaproteobacteria,43SFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_61587_39	331113.SNE_A23130	2.678e-32	146.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae	204428|Chlamydiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_61587_13	1121920.AUAU01000004_gene773	2.999e-77	282.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K02172	ko01501,ko01503,map01501,map01503	M00627,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1
GDHHQS3_k127_61587_9	1158318.ATXC01000001_gene807	1.047e-99	342.0	COG2805@1|root,COG2805@2|Bacteria,2G3S2@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_61587_31	1125863.JAFN01000001_gene522	1.68e-44	171.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_61587_8	861299.J421_0916	3.106e-107	362.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_61587_18	861299.J421_0915	1.089e-70	267.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_61587_17	330214.NIDE1530	1.591e-73	275.0	COG0515@1|root,COG0515@2|Bacteria	330214.NIDE1530|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GDHHQS3_k127_61587_0	234267.Acid_7675	7.57e-214	686.0	COG0480@1|root,COG0480@2|Bacteria,3Y2RR@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_61587_21	1382359.JIAL01000001_gene1200	1.511e-58	208.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria,2JIEA@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS3_k127_61587_37	404380.Gbem_0961	7.857e-34	138.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,43V08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS3_k127_61587_7	1267533.KB906735_gene5103	1.691e-111	368.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS3_k127_61587_11	398767.Glov_1372	8.585e-86	288.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS3_k127_61587_25	204669.Acid345_1252	1.704e-52	188.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS3_k127_61587_32	240015.ACP_1426	3.759e-44	164.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria,2JJAF@204432|Acidobacteriia	204432|Acidobacteriia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS3_k127_61587_50	694431.DESACE_01960	4.958e-12	71.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS3_k127_61587_38	903818.KI912268_gene2253	7.512e-33	131.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS3_k127_61587_14	644282.Deba_2916	2.601e-76	286.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_61587_29	1211114.ALIP01000118_gene2089	5.754e-48	178.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1X668@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
GDHHQS3_k127_61587_1	1047013.AQSP01000074_gene1894	8.555e-189	601.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS3_k127_61587_33	273068.TTE2273	1.135e-43	169.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GDHHQS3_k127_61587_51	1387197.AWGA01000068_gene823	4.627e-11	72.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Ribosomal protein L30	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
GDHHQS3_k127_61587_24	1121918.ARWE01000001_gene2256	2.564e-57	207.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,43SEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S5, C-terminal domain	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GDHHQS3_k127_61587_36	1031288.AXAA01000031_gene105	3.7e-38	147.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,36JQ0@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
GDHHQS3_k127_61587_22	404589.Anae109_1926	7.88e-58	206.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2YV6Z@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GDHHQS3_k127_61587_34	880072.Desac_1442	1.383e-41	156.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MQJ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
GDHHQS3_k127_61587_48	880073.Calab_2139	1.6e-18	86.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
GDHHQS3_k127_61587_16	903818.KI912268_gene2263	1.068e-75	265.0	COG0094@1|root,COG0094@2|Bacteria,3Y3PS@57723|Acidobacteria	57723|Acidobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
GDHHQS3_k127_61587_40	246194.CHY_2298	8.694e-30	122.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
GDHHQS3_k127_61587_27	204669.Acid345_1236	8.777e-50	179.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
GDHHQS3_k127_61587_47	1304880.JAGB01000003_gene1201	2.49e-19	95.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
GDHHQS3_k127_61587_53	1121472.AQWN01000002_gene2048	0.0002089	49.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,262YR@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
GDHHQS3_k127_61587_23	671143.DAMO_0546	8.724e-58	203.0	COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria	2|Bacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
GDHHQS3_k127_61587_12	1449049.JONW01000007_gene3799	4.44e-83	287.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2KG54@204458|Caulobacterales	204458|Caulobacterales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
GDHHQS3_k127_61587_42	1120972.AUMH01000017_gene722	1.101e-26	116.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,278GN@186823|Alicyclobacillaceae	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
GDHHQS3_k127_61587_35	240015.ACP_1447	1.221e-38	146.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria,2JJMI@204432|Acidobacteriia	204432|Acidobacteriia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
GDHHQS3_k127_61587_6	1192034.CAP_0435	1.479e-119	393.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2YTYD@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
GDHHQS3_k127_61587_43	439235.Dalk_1913	2.997e-24	113.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MKJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
GDHHQS3_k127_61587_30	1340493.JNIF01000003_gene3208	1.124e-46	184.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GDHHQS3_k127_61587_19	1121920.AUAU01000010_gene103	1.473e-70	245.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GDHHQS3_k127_61587_28	1340493.JNIF01000003_gene3206	3.174e-48	174.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria	57723|Acidobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GDHHQS3_k127_61587_15	640081.Dsui_0361	5.365e-76	256.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,2KVV4@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_6176197_0	639030.JHVA01000001_gene421	8.792e-173	575.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS3_k127_6176197_1	1125863.JAFN01000001_gene3055	3.939e-149	502.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
GDHHQS3_k127_6176197_5	1211035.CD30_13805	2.17e-38	158.0	COG0500@1|root,COG0500@2|Bacteria,1UN2E@1239|Firmicutes	1239|Firmicutes	Q	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	MetW,Methyltransf_23
GDHHQS3_k127_6176197_6	882.DVU_0958	4.095e-30	134.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2MAU8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS3_k127_6176197_7	1340493.JNIF01000004_gene997	1.158e-22	99.0	COG0238@1|root,COG0238@2|Bacteria	2|Bacteria	J	rRNA binding	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS3_k127_6176197_8	240015.ACP_2066	2.296e-19	93.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria,2JJHP@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS3_k127_6176197_3	477974.Daud_0071	1.818e-42	164.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,261YC@186807|Peptococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS3_k127_6176197_4	1379698.RBG1_1C00001G0172	2.797e-41	163.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS3_k127_6176197_2	502025.Hoch_4501	2.469e-54	194.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2YUB9@29|Myxococcales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
GDHHQS3_k127_625492_9	861299.J421_5712	1.972e-70	256.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5712|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_625492_2	1242864.D187_006882	3.72e-180	621.0	COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_625492_3	1297742.A176_04241	1.011e-159	533.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_625492_6	452637.Oter_1900	2.867e-110	360.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_625492_5	251221.35211836	3.189e-121	407.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_625492_12	1121861.KB899910_gene663	3.936e-55	216.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
GDHHQS3_k127_625492_11	1121861.KB899910_gene663	1.432e-57	223.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
GDHHQS3_k127_625492_4	526227.Mesil_2557	1.62e-126	426.0	COG0010@1|root,COG0010@2|Bacteria,1WI2B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_625492_13	796606.BMMGA3_13180	4.075e-44	168.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,4HH5V@91061|Bacilli,1ZFK1@1386|Bacillus	91061|Bacilli	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
GDHHQS3_k127_625492_10	1300345.LF41_1473	3.099e-61	230.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RY2M@1236|Gammaproteobacteria,1X6IZ@135614|Xanthomonadales	135614|Xanthomonadales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,dCache_1
GDHHQS3_k127_625492_18	573370.DMR_14340	1.454e-15	79.0	29XTP@1|root,30JJR@2|Bacteria,1QTBX@1224|Proteobacteria,436Y4@68525|delta/epsilon subdivisions,2X1NB@28221|Deltaproteobacteria,2MFCX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_625492_15	712898.Pvag_1818	6.971e-21	97.0	COG2261@1|root,COG2261@2|Bacteria,1QID9@1224|Proteobacteria,1TG7J@1236|Gammaproteobacteria,3W17Z@53335|Pantoea	1236|Gammaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_625492_1	292459.STH848	3.087e-190	625.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_625492_19	342113.DM82_4743	7.499e-12	69.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,2VU4R@28216|Betaproteobacteria,1KHIE@119060|Burkholderiaceae	28216|Betaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_625492_20	591157.SSLG_00558	1.155e-05	48.0	COG0607@1|root,COG0607@2|Bacteria,2IIWA@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_625492_17	990285.RGCCGE502_15655	1.17e-15	89.0	COG0662@1|root,COG0662@2|Bacteria,1NV7E@1224|Proteobacteria,2URV3@28211|Alphaproteobacteria,4BDZQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_625492_0	1297742.A176_02164	0.0	1070.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
GDHHQS3_k127_625492_7	1300345.LF41_1842	2.818e-107	376.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GDHHQS3_k127_625492_16	744872.Spica_0070	2.053e-17	97.0	298ZI@1|root,2ZW3A@2|Bacteria	2|Bacteria	S	ECF transporter, substrate-specific component	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
GDHHQS3_k127_625492_8	215803.DB30_5313	2.299e-92	318.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
GDHHQS3_k127_625492_14	1144275.COCOR_06255	3.867e-42	179.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS3_k127_627069_44	398767.Glov_1844	1.393e-53	203.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
GDHHQS3_k127_627069_8	1121920.AUAU01000030_gene2723	1.407e-152	495.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_627069_3	575540.Isop_3556	4.89e-192	623.0	COG1012@1|root,COG1012@2|Bacteria,2IXUZ@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_627069_64	1385935.N836_15175	9.842e-15	88.0	COG1807@1|root,COG1807@2|Bacteria,1GI8H@1117|Cyanobacteria,1HETH@1150|Oscillatoriales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_627069_14	404589.Anae109_0438	8.415e-143	487.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2YWE1@29|Myxococcales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
GDHHQS3_k127_627069_38	335543.Sfum_2672	4.833e-66	250.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
GDHHQS3_k127_627069_39	335543.Sfum_2673	5.19e-62	228.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
GDHHQS3_k127_627069_29	391625.PPSIR1_10520	2.007e-86	313.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
GDHHQS3_k127_627069_26	1121033.AUCF01000016_gene5495	6.018e-101	349.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria,2JQ2G@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD binding domain	-	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GDHHQS3_k127_627069_16	1121920.AUAU01000004_gene632	3.485e-134	466.0	COG1629@1|root,COG4771@2|Bacteria,3Y2HF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS3_k127_627069_52	1172188.KB911823_gene547	2.127e-45	182.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4FFRP@85021|Intrasporangiaceae	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
GDHHQS3_k127_627069_66	635013.TherJR_0696	1.598e-12	83.0	COG3411@1|root,COG3411@2|Bacteria,1VCJG@1239|Firmicutes,24JC4@186801|Clostridia,265J0@186807|Peptococcaceae	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx,DUF1636
GDHHQS3_k127_627069_55	383372.Rcas_0482	1.968e-39	166.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM9_2,DUF362
GDHHQS3_k127_627069_40	1242864.D187_010364	1.151e-61	224.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS3_k127_627069_24	502025.Hoch_0162	1.509e-106	361.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42S4P@68525|delta/epsilon subdivisions,2WNK7@28221|Deltaproteobacteria,2YVAH@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GDHHQS3_k127_627069_7	1122134.KB893650_gene584	2.603e-161	529.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales	135619|Oceanospirillales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GDHHQS3_k127_627069_70	1382359.JIAL01000001_gene454	1.48e-05	57.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria,2JIN1@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GDHHQS3_k127_627069_49	1185876.BN8_04892	5.881e-46	176.0	COG0739@1|root,COG0739@2|Bacteria,4NIQN@976|Bacteroidetes,47JX9@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_627069_63	1112212.JH584235_gene3839	9.296e-16	91.0	COG3714@1|root,COG3714@2|Bacteria,1RFIR@1224|Proteobacteria,2U8S6@28211|Alphaproteobacteria,2K6KU@204457|Sphingomonadales	204457|Sphingomonadales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
GDHHQS3_k127_627069_21	596151.DesfrDRAFT_0289	1.116e-112	382.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2M8I4@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_627069_62	1122604.JONR01000042_gene3451	1.589e-24	111.0	2EBUX@1|root,335UE@2|Bacteria,1NAYE@1224|Proteobacteria,1T8Q1@1236|Gammaproteobacteria,1XB2A@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_627069_35	1379698.RBG1_1C00001G0779	8.534e-73	276.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GDHHQS3_k127_627069_18	671143.DAMO_0821	5.521e-127	418.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
GDHHQS3_k127_627069_57	1379698.RBG1_1C00001G0781	9.117e-36	141.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
GDHHQS3_k127_627069_56	443144.GM21_0398	4.022e-38	164.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Ail_Lom,MtrB_PioB
GDHHQS3_k127_627069_36	1123367.C666_11675	2.911e-72	255.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria,2KUB7@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS3_k127_627069_12	452637.Oter_2603	4.857e-145	487.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
GDHHQS3_k127_627069_72	641491.DND132_2106	5.867e-05	54.0	COG1271@1|root,COG1271@2|Bacteria,1PG1H@1224|Proteobacteria,437AC@68525|delta/epsilon subdivisions,2WUDD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_627069_41	583355.Caka_1355	2.605e-60	226.0	COG0654@1|root,COG0654@2|Bacteria,46VIV@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GDHHQS3_k127_627069_13	1232410.KI421413_gene474	1.123e-144	475.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria,43U0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
GDHHQS3_k127_627069_61	1278073.MYSTI_07636	2.76e-29	130.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_627069_1	215803.DB30_0967	5.525e-228	726.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,43BWY@68525|delta/epsilon subdivisions,2X77Q@28221|Deltaproteobacteria,2YXSH@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamine synthetase, beta-Grasp domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_627069_15	926550.CLDAP_07090	1.395e-140	460.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_627069_32	765912.Thimo_0216	9.183e-81	295.0	COG0845@1|root,COG1357@1|root,COG2319@1|root,COG5635@1|root,COG0845@2|Bacteria,COG1357@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1WXXD@135613|Chromatiales	135613|Chromatiales	M	PFAM WD40 repeat, subgroup	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
GDHHQS3_k127_627069_28	497964.CfE428DRAFT_4291	1.179e-90	332.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_627069_9	861299.J421_3743	1.033e-150	490.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_627069_22	335543.Sfum_3112	3.375e-107	364.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_627069_37	76114.ebA6058	8.119e-67	246.0	COG0784@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2200@2|Bacteria,1NC9X@1224|Proteobacteria,2WGSU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
GDHHQS3_k127_627069_69	215803.DB30_1686	1.566e-09	64.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YYJJ@29|Myxococcales	28221|Deltaproteobacteria	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,PilZ
GDHHQS3_k127_627069_17	483219.LILAB_29405	1.654e-132	437.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_627069_59	1123367.C666_08030	6.191e-32	138.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,2KUU5@206389|Rhodocyclales	206389|Rhodocyclales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
GDHHQS3_k127_627069_58	1168065.DOK_06397	2.639e-35	153.0	28R4I@1|root,2ZDIV@2|Bacteria,1RB8F@1224|Proteobacteria,1S2NM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_627069_27	1128421.JAGA01000003_gene2811	4.639e-98	356.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_627069_11	288000.BBta_6315	4.919e-147	519.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3JR2T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS3_k127_627069_19	1187851.A33M_2348	1.114e-125	415.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3FDFW@34008|Rhodovulum	28211|Alphaproteobacteria	J	Phosphoglucose isomerase	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS3_k127_627069_31	443143.GM18_0786	4.398e-81	301.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
GDHHQS3_k127_627069_30	404589.Anae109_1840	4.027e-81	297.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
GDHHQS3_k127_627069_47	1283299.AUKG01000001_gene2260	4.157e-48	188.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_627069_45	234267.Acid_4635	1.549e-53	197.0	COG1216@1|root,COG1216@2|Bacteria,3Y9AS@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_627069_71	1894.JOER01000026_gene1687	2.268e-05	59.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
GDHHQS3_k127_627069_50	1173022.Cri9333_3490	1.188e-45	183.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_627069_53	985054.JQEZ01000001_gene1878	4.437e-44	176.0	COG0438@1|root,COG0438@2|Bacteria,1PERI@1224|Proteobacteria,2V82U@28211|Alphaproteobacteria,4NDJT@97050|Ruegeria	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GDHHQS3_k127_627069_10	1120956.JHZK01000009_gene1715	1.741e-150	498.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,1JN2N@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_627069_46	525898.Sdel_2220	2.115e-53	208.0	COG0500@1|root,COG2835@1|root,COG0500@2|Bacteria,COG2835@2|Bacteria,1R0S1@1224|Proteobacteria,43D0F@68525|delta/epsilon subdivisions,2YS5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_627069_51	1121438.JNJA01000011_gene1805	1.328e-45	190.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42MC8@68525|delta/epsilon subdivisions,2WPR0@28221|Deltaproteobacteria,2MBRZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_627069_65	224324.aq_509	6.286e-14	85.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_627069_2	1260251.SPISAL_07325	2.916e-217	697.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales	135613|Chromatiales	P	PUA-like domain	-	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
GDHHQS3_k127_627069_42	903818.KI912268_gene1614	3.075e-59	214.0	COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GDHHQS3_k127_627069_5	1089553.Tph_c27810	7.509e-169	544.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,42EXD@68295|Thermoanaerobacterales	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_627069_54	1121430.JMLG01000002_gene1010	1.64e-41	162.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261XK@186807|Peptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
GDHHQS3_k127_627069_0	1089553.Tph_c04670	1.356e-271	860.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_627069_4	1120985.AUMI01000014_gene1122	1.058e-175	559.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H2EF@909932|Negativicutes	909932|Negativicutes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GDHHQS3_k127_627069_33	1500890.JQNL01000001_gene600	2.192e-79	273.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1X3W7@135614|Xanthomonadales	135614|Xanthomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS3_k127_627069_48	1267535.KB906767_gene3230	2.324e-47	188.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GDHHQS3_k127_627069_68	251221.35210963	1.205e-10	72.0	COG2104@1|root,COG2104@2|Bacteria,1G986@1117|Cyanobacteria	1117|Cyanobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
GDHHQS3_k127_627069_60	1121920.AUAU01000025_gene2317	2.488e-30	130.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_627069_23	1379698.RBG1_1C00001G0806	1.144e-106	354.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS3_k127_627069_20	1379698.RBG1_1C00001G0804	3.175e-122	406.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_627069_43	748247.AZKH_2147	1.094e-56	209.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_627069_34	1071085.KK033114_gene1191	2.363e-74	267.0	COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS3_k127_627069_25	109760.SPPG_04804T0	3.857e-101	340.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_627069_6	502025.Hoch_5092	5.942e-167	547.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2YYUX@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
GDHHQS3_k127_6521070_3	204669.Acid345_4118	2.142e-48	182.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_6521070_1	204669.Acid345_4118	1.44e-59	233.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_6521070_5	998088.B565_2726	0.0003827	53.0	2DVVX@1|root,33XES@2|Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GDHHQS3_k127_6521070_4	932678.THERU_07975	5.668e-08	62.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_6521070_0	1267534.KB906755_gene4692	1.78e-70	259.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6521070_2	1267534.KB906755_gene4691	2.326e-52	199.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_6731005_5	1034943.BN1094_00038	1.516e-125	420.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1JC52@118969|Legionellales	118969|Legionellales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS3_k127_6731005_1	1121920.AUAU01000006_gene330	8.864e-317	987.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_6731005_2	204669.Acid345_3936	1.616e-315	985.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_6731005_3	204669.Acid345_3936	3.41e-306	957.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_6731005_10	1121439.dsat_1279	1.867e-40	166.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria,2MATU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_6731005_9	365046.Rta_07820	9.681e-51	206.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2VJ35@28216|Betaproteobacteria,4ADA3@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	eat	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
GDHHQS3_k127_6731005_13	530564.Psta_3545	3.047e-06	55.0	COG2331@1|root,COG2331@2|Bacteria,2J18U@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_6731005_4	926550.CLDAP_19050	2.072e-190	617.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_6731005_0	760117.JN27_18540	0.0	1073.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476SF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_6731005_6	404589.Anae109_1629	8.983e-122	412.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
GDHHQS3_k127_6731005_7	1354722.JQLS01000008_gene3743	7.93e-59	232.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,46PGZ@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_6731005_8	671143.DAMO_2996	5.819e-53	216.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS3_k127_6731005_12	195522.BD01_2040	1.612e-23	114.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,242VX@183968|Thermococci	183968|Thermococci	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
GDHHQS3_k127_6731005_11	317619.ANKN01000188_gene3652	4.574e-30	123.0	COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria,1MMAN@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS3_k127_678428_3	1121033.AUCF01000005_gene5309	6.793e-95	329.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS3_k127_678428_2	204669.Acid345_1588	1.528e-100	359.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_678428_16	247634.GPB2148_2134	7.718e-14	87.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1J4N1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1	comC	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
GDHHQS3_k127_678428_19	1242864.D187_002308	6.434e-07	64.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria,2YW3S@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
GDHHQS3_k127_678428_21	859657.RPSI07_2612	0.0008772	51.0	COG4966@1|root,COG4966@2|Bacteria,1R5TH@1224|Proteobacteria,2VVQG@28216|Betaproteobacteria,1K1TH@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type iv pilus assembly protein	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
GDHHQS3_k127_678428_12	644966.Tmar_0284	4.805e-33	149.0	COG2203@1|root,COG3437@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24IAZ@186801|Clostridia,3WD9X@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9
GDHHQS3_k127_678428_7	398767.Glov_2160	2.683e-57	208.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS3_k127_678428_8	204669.Acid345_4600	1.403e-47	190.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_678428_14	1047013.AQSP01000115_gene360	6.949e-16	85.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GDHHQS3_k127_678428_10	100226.SCO0571	1.054e-33	147.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_678428_17	926569.ANT_11560	3.01e-13	83.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_678428_4	1128421.JAGA01000002_gene736	6.982e-88	303.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_678428_6	439235.Dalk_1881	4.516e-60	237.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_678428_20	1192034.CAP_5894	2.741e-06	61.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	yhcR	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,ChitinaseA_N,Glyco_hydro_18,Glyco_hydro_53,Reprolysin_4,fn3
GDHHQS3_k127_678428_15	298653.Franean1_6403	1.001e-15	91.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_678428_0	530564.Psta_3553	7.103e-220	693.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	203682|Planctomycetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_678428_13	767817.Desgi_4711	2.546e-20	109.0	COG3307@1|root,COG3307@2|Bacteria,1UR78@1239|Firmicutes,24W38@186801|Clostridia	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS3_k127_678428_5	596151.DesfrDRAFT_0774	1.025e-87	310.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_678428_11	1121438.JNJA01000001_gene2120	2.517e-33	149.0	COG0438@1|root,COG0438@2|Bacteria,1R11H@1224|Proteobacteria,43D5I@68525|delta/epsilon subdivisions,2X8C9@28221|Deltaproteobacteria,2M8ZK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
GDHHQS3_k127_678428_1	1183438.GKIL_1591	2.24e-127	417.0	COG0451@1|root,COG0451@2|Bacteria,1G457@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_678428_18	1280663.ATVR01000008_gene2015	2.106e-09	69.0	2E4Z9@1|root,32ZSZ@2|Bacteria,1W06Q@1239|Firmicutes,252X3@186801|Clostridia	186801|Clostridia	S	WavE lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	WavE
GDHHQS3_k127_678428_9	448385.sce6682	1.255e-36	146.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
GDHHQS3_k127_6789522_6	518766.Rmar_0288	1.283e-52	207.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4NI98@976|Bacteroidetes	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS3_k127_6789522_12	487796.Flav2ADRAFT_1528	3.87e-24	105.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GDHHQS3_k127_6789522_14	487796.Flav2ADRAFT_1527	5.705e-21	98.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS3_k127_6789522_4	525897.Dbac_2942	9.576e-76	278.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_6789522_10	1499967.BAYZ01000159_gene502	5.345e-36	158.0	COG2203@1|root,COG2208@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3437@2|Bacteria,2NQW9@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3,4.6.1.1	ko:K01079,ko:K01768,ko:K07315	ko00230,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02025,ko04113,ko04213,map00230,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02025,map04113,map04213	M00020,M00695	R00089,R00434,R00582	RC00017,RC00295	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HATPase_c_2,Response_reg,SSF,SpoIIE
GDHHQS3_k127_6789522_0	498761.HM1_1297	0.0	1175.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS3_k127_6789522_18	1123504.JQKD01000002_gene3713	0.0004045	50.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,2VRES@28216|Betaproteobacteria,4AG0K@80864|Comamonadaceae	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_6789522_1	234267.Acid_4535	5.224e-111	392.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_6789522_5	497964.CfE428DRAFT_3372	3.701e-54	193.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	PIN,PIN_3
GDHHQS3_k127_6789522_9	1184267.A11Q_1018	7.893e-39	163.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2MTBA@213481|Bdellovibrionales,2WM41@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GDHHQS3_k127_6789522_8	518637.EUBIFOR_01017	2.787e-40	154.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,3VQI2@526524|Erysipelotrichia	526524|Erysipelotrichia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS3_k127_6789522_19	1121403.AUCV01000024_gene3405	0.0005214	50.0	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
GDHHQS3_k127_6789522_3	1047013.AQSP01000072_gene986	2.973e-101	364.0	COG5000@1|root,COG5000@2|Bacteria,2NQRV@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GDHHQS3_k127_6789522_11	1206737.BAGF01000058_gene3625	1.024e-25	122.0	COG1073@1|root,COG1073@2|Bacteria,2IA0F@201174|Actinobacteria,4FUH3@85025|Nocardiaceae	201174|Actinobacteria	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS3_k127_6789522_17	936136.ARRT01000006_gene1432	4.755e-13	83.0	COG1309@1|root,COG1309@2|Bacteria,1NUS4@1224|Proteobacteria,2TQSX@28211|Alphaproteobacteria,4B926@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	tcmR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_6789522_2	292459.STH1073	2.06e-108	376.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia	186801|Clostridia	J	Translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS3_k127_6789522_16	2880.D7FPS1	2.804e-13	81.0	2CYF6@1|root,2S3ZG@2759|Eukaryota	2759|Eukaryota	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
GDHHQS3_k127_6789522_7	644966.Tmar_1526	5.251e-47	186.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3WDEV@538999|Clostridiales incertae sedis	186801|Clostridia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS3_k127_6789522_15	1234364.AMSF01000015_gene3085	2.209e-14	80.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1SEGZ@1236|Gammaproteobacteria,1XC15@135614|Xanthomonadales	135614|Xanthomonadales	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS3_k127_6958563_7	204669.Acid345_4218	2.124e-116	392.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria,2JIAX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
GDHHQS3_k127_6958563_27	1415780.JPOG01000001_gene1646	3.559e-21	104.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1X5YX@135614|Xanthomonadales	135614|Xanthomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
GDHHQS3_k127_6958563_9	1121405.dsmv_2951	2.262e-94	328.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_6958563_4	269799.Gmet_0776	2.798e-145	473.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_6958563_18	771875.Ferpe_0842	2.159e-48	181.0	COG0461@1|root,COG0461@2|Bacteria,2GD2M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_6958563_6	404589.Anae109_2136	4.086e-143	463.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_6958563_8	1462527.CCDM010000001_gene2368	7.604e-97	346.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,23IV7@182709|Oceanobacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_6958563_19	351160.LRC548	1.912e-43	177.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
GDHHQS3_k127_6958563_2	234267.Acid_6472	1.892e-217	697.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria	57723|Acidobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_6958563_22	1379698.RBG1_1C00001G0743	1.945e-30	127.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
GDHHQS3_k127_6958563_16	1047013.AQSP01000106_gene1773	4.234e-50	201.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
GDHHQS3_k127_6958563_15	243231.GSU1578	1.038e-51	186.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,43UUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS3_k127_6958563_21	404589.Anae109_1476	7.131e-39	160.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_6958563_1	1125863.JAFN01000001_gene800	4.029e-257	836.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS3_k127_6958563_26	1122925.KB895379_gene2154	1.453e-21	108.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
GDHHQS3_k127_6958563_11	760568.Desku_3200	1.566e-87	297.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS3_k127_6958563_17	292459.STH473	3.672e-49	199.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS3_k127_6958563_12	1442599.JAAN01000031_gene1339	1.988e-67	240.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1X3TF@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS3_k127_6958563_29	888060.HMPREF9081_1065	5.048e-12	73.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4H54S@909932|Negativicutes	909932|Negativicutes	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
GDHHQS3_k127_6958563_24	269799.Gmet_0822	2.977e-25	122.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,42TIF@68525|delta/epsilon subdivisions,2WQC4@28221|Deltaproteobacteria,43SR3@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA-2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_6958563_0	1499967.BAYZ01000009_gene5298	0.0	1060.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
GDHHQS3_k127_6958563_25	1380370.JIBA01000014_gene1932	1.854e-22	107.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4FGPC@85021|Intrasporangiaceae	201174|Actinobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS3_k127_6958563_14	871968.DESME_15085	2.402e-53	213.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,25BFU@186801|Clostridia	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_6958563_20	1121468.AUBR01000020_gene2849	2.576e-42	165.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,42FJD@68295|Thermoanaerobacterales	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS3_k127_6958563_10	398767.Glov_3125	2.451e-89	330.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_6958563_5	671143.DAMO_2691	6.056e-145	502.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_6958563_3	1267211.KI669560_gene962	2.731e-163	535.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_6958563_23	309807.SRU_1444	1.581e-26	111.0	COG0713@1|root,COG0713@2|Bacteria,4NWKU@976|Bacteroidetes,1FJJ2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS3_k127_6958563_28	1125863.JAFN01000001_gene2412	6.676e-17	93.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2WSB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_6958563_13	886293.Sinac_2285	5.046e-59	210.0	COG1005@1|root,COG1005@2|Bacteria,2IXH1@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_7011295_0	1142394.PSMK_30660	1.499e-188	606.0	COG4631@1|root,COG4631@2|Bacteria,2J56Q@203682|Planctomycetes	203682|Planctomycetes	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4,1.17.3.2	ko:K00106,ko:K13482	ko00230,ko00232,ko00983,ko01100,ko01110,ko01120,ko04146,map00230,map00232,map00983,map01100,map01110,map01120,map04146	M00546	R01768,R01769,R02103,R02107,R07942,R07977,R07978,R07979,R08235	RC00143,RC02017,RC02199	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_7011295_6	414684.RC1_1684	9.081e-62	219.0	COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,2U8CX@28211|Alphaproteobacteria,2JSQK@204441|Rhodospirillales	204441|Rhodospirillales	FJ	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_7011295_7	1121920.AUAU01000019_gene2604	9.012e-39	153.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
GDHHQS3_k127_7011295_3	857087.Metme_0581	2.351e-99	346.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7011295_9	1121015.N789_07825	2.942e-25	124.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X42D@135614|Xanthomonadales	135614|Xanthomonadales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GDHHQS3_k127_7011295_1	1142394.PSMK_30990	3.781e-160	531.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GDHHQS3_k127_7011295_10	997346.HMPREF9374_1278	1.44e-07	57.0	2DRFR@1|root,33BIP@2|Bacteria,1UBQS@1239|Firmicutes,4IN5S@91061|Bacilli,27CBE@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	DUF454,PGPGW
GDHHQS3_k127_7011295_2	243233.MCA1833	5.205e-112	372.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
GDHHQS3_k127_7011295_4	251221.35213669	5.998e-81	303.0	COG4948@1|root,COG4948@2|Bacteria,1FZYA@1117|Cyanobacteria	1117|Cyanobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.2.1.113,5.1.1.20	ko:K02549,ko:K19802	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031,R10938	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_7011295_5	1379270.AUXF01000003_gene3585	7.038e-76	284.0	COG3653@1|root,COG3653@2|Bacteria,1ZUQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GDHHQS3_k127_7022000_15	626418.bglu_2g02060	6.199e-34	135.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,2VT3H@28216|Betaproteobacteria,1K1XS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
GDHHQS3_k127_7022000_0	1411123.JQNH01000001_gene968	4.036e-245	782.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GDHHQS3_k127_7022000_9	448385.sce2664	1.903e-77	274.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YV5B@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GDHHQS3_k127_7022000_13	1297742.A176_02222	3.659e-34	138.0	COG1633@1|root,COG1633@2|Bacteria,1QX6R@1224|Proteobacteria,432ES@68525|delta/epsilon subdivisions,2WYEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
GDHHQS3_k127_7022000_7	1216976.AX27061_2812	6.029e-98	331.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,3T1SJ@506|Alcaligenaceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
GDHHQS3_k127_7022000_12	1169144.KB910935_gene2035	5.614e-45	173.0	COG1388@1|root,COG1388@2|Bacteria,1V4GT@1239|Firmicutes,4IPSP@91061|Bacilli	91061|Bacilli	M	LysM domain	M1-670	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7022000_17	644076.SCH4B_2050	1.975e-20	92.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,4NCU6@97050|Ruegeria	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS3_k127_7022000_4	1379698.RBG1_1C00001G0607	4.647e-157	522.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_7022000_2	502025.Hoch_1577	3.788e-167	557.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_7022000_11	926566.Terro_0014	1.003e-57	207.0	2AYX9@1|root,31R2Z@2|Bacteria,3Y4ZH@57723|Acidobacteria,2JJGK@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_7022000_3	234267.Acid_4431	4.243e-161	540.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7022000_1	502025.Hoch_1577	8.126e-186	613.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_7022000_8	204669.Acid345_2716	5.806e-94	346.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7022000_16	1122221.JHVI01000019_gene1158	5.286e-33	134.0	COG2402@1|root,COG2402@2|Bacteria,1WJXR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_7022000_5	234267.Acid_4431	1.96e-156	529.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7022000_10	1430440.MGMSRv2_1777	7.334e-68	253.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,2TWBW@28211|Alphaproteobacteria,2JPN9@204441|Rhodospirillales	204441|Rhodospirillales	T	Stimulus-sensing domain	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
GDHHQS3_k127_7022000_14	1144310.PMI07_006229	4.814e-34	143.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,4BBRE@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Two component transcriptional regulator	-	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_7022000_6	1282876.BAOK01000001_gene1269	3.179e-109	379.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,2TV9Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GDHHQS3_k127_7164940_2	502025.Hoch_1577	6.118e-159	533.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_7164940_0	234267.Acid_4431	2.96e-170	567.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7164940_4	204669.Acid345_4392	3.374e-140	488.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_7164940_7	1123386.AUIW01000009_gene1813	1.967e-06	53.0	2DGZ3@1|root,2ZXUD@2|Bacteria,1WKRC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_7164940_8	326424.FRAAL0552	2.014e-06	57.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_7164940_3	234267.Acid_3938	1.451e-142	488.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7164940_1	234267.Acid_4431	4.293e-167	558.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7164940_6	471853.Bcav_2738	5.692e-12	70.0	COG2002@1|root,COG2002@2|Bacteria,2HDIV@201174|Actinobacteria	201174|Actinobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_7164940_5	471853.Bcav_2739	1.193e-28	123.0	COG1487@1|root,COG1487@2|Bacteria,2INNM@201174|Actinobacteria	201174|Actinobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_7171524_54	485918.Cpin_5464	3.235e-05	55.0	COG1225@1|root,COG2259@1|root,COG1225@2|Bacteria,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
GDHHQS3_k127_7171524_50	937777.Deipe_0516	1.671e-11	77.0	COG1714@1|root,COG1714@2|Bacteria,1WKUI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS3_k127_7171524_49	1192034.CAP_0383	5.478e-12	79.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GDHHQS3_k127_7171524_3	1382359.JIAL01000001_gene2777	5.657e-247	796.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS3_k127_7171524_15	290397.Adeh_0200	1.888e-76	269.0	COG1612@1|root,COG1612@2|Bacteria,1PV6F@1224|Proteobacteria,4303Y@68525|delta/epsilon subdivisions,2WVAK@28221|Deltaproteobacteria,2YUJ2@29|Myxococcales	28221|Deltaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS3_k127_7171524_7	330214.NIDE3591	1.4e-132	457.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GDHHQS3_k127_7171524_58	405948.SACE_1886	0.0005033	50.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4E5BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_7171524_2	1123278.KB893558_gene3264	1.958e-250	794.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GDHHQS3_k127_7171524_36	377629.TERTU_0024	8.982e-30	130.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,2PQD7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7171524_21	1089552.KI911559_gene1110	1.961e-57	207.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2JRS3@204441|Rhodospirillales	204441|Rhodospirillales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GDHHQS3_k127_7171524_24	1449063.JMLS01000002_gene1289	5.718e-53	192.0	COG2318@1|root,COG2318@2|Bacteria,1V415@1239|Firmicutes,4HH2D@91061|Bacilli,26YZ8@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GDHHQS3_k127_7171524_38	1123508.JH636441_gene3427	1.563e-28	120.0	2E3V1@1|root,32YSA@2|Bacteria,2J1BP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7171524_0	391625.PPSIR1_35712	0.0	1392.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GDHHQS3_k127_7171524_25	391625.PPSIR1_24779	1.291e-46	186.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_7171524_26	105559.Nwat_1044	3.275e-43	179.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria	1224|Proteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7171524_11	379066.GAU_2025	4.209e-95	327.0	COG2355@1|root,COG2355@2|Bacteria,1ZU9D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS3_k127_7171524_35	926566.Terro_0790	1.132e-30	132.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria,2JNIT@204432|Acidobacteriia	204432|Acidobacteriia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS3_k127_7171524_45	106370.Francci3_1913	8.26e-18	92.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GDHHQS3_k127_7171524_43	8932.XP_005502493.1	3.628e-21	104.0	COG1028@1|root,KOG1208@2759|Eukaryota,38CZD@33154|Opisthokonta,3BACQ@33208|Metazoa,3CSEJ@33213|Bilateria,4883Z@7711|Chordata,4917U@7742|Vertebrata,4GQU8@8782|Aves	33208|Metazoa	Q	retinol dehydrogenase	RDH12	GO:0001523,GO:0001894,GO:0001895,GO:0001917,GO:0003008,GO:0003674,GO:0003824,GO:0004033,GO:0004745,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006066,GO:0006081,GO:0006629,GO:0006720,GO:0006721,GO:0007154,GO:0007165,GO:0007186,GO:0007600,GO:0007601,GO:0007602,GO:0007603,GO:0008106,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009628,GO:0009642,GO:0009966,GO:0009987,GO:0010646,GO:0010817,GO:0012505,GO:0016020,GO:0016056,GO:0016062,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0023051,GO:0023052,GO:0023058,GO:0031984,GO:0032501,GO:0034308,GO:0034754,GO:0036367,GO:0042175,GO:0042445,GO:0042572,GO:0042574,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045494,GO:0048583,GO:0048871,GO:0050789,GO:0050794,GO:0050877,GO:0050896,GO:0050953,GO:0051606,GO:0051716,GO:0052650,GO:0055114,GO:0060249,GO:0060342,GO:0065007,GO:0065008,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071944,GO:0097458,GO:0098590,GO:0098827,GO:0104004,GO:1901615	1.1.1.300	ko:K11152,ko:K11153	ko00830,ko01100,map00830,map01100	-	R08379,R08380,R08383	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
GDHHQS3_k127_7171524_16	1411123.JQNH01000001_gene2502	1.245e-74	256.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_7171524_20	349521.HCH_04045	3.938e-58	218.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XS7F@135619|Oceanospirillales	135619|Oceanospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_7171524_14	290397.Adeh_2651	3.392e-87	304.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_7171524_23	316274.Haur_0049	1.757e-55	201.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_7171524_40	452637.Oter_0829	1.61e-25	115.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7171524_19	1054213.HMPREF9946_03239	2.065e-60	215.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VETM@28211|Alphaproteobacteria,2JYMX@204441|Rhodospirillales	204441|Rhodospirillales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7171524_29	234267.Acid_6462	1.475e-37	155.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4
GDHHQS3_k127_7171524_31	667632.KB890164_gene2209	1.285e-36	154.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria	1224|Proteobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K05518	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GDHHQS3_k127_7171524_32	686340.Metal_2794	3.274e-35	139.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,1SCWT@1236|Gammaproteobacteria,1XFTA@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
GDHHQS3_k127_7171524_28	1415166.NONO_c33660	1.058e-42	159.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4G0GD@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS3_k127_7171524_9	1206737.BAGF01000045_gene2830	4.686e-115	378.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria,4FU8E@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
GDHHQS3_k127_7171524_57	321327.CYA_2773	0.0004016	54.0	COG0642@1|root,COG4250@1|root,COG2205@2|Bacteria,COG4250@2|Bacteria,1G01S@1117|Cyanobacteria,1GZ4W@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE6_C,DICT,GAF,HATPase_c,HisKA
GDHHQS3_k127_7171524_27	1242864.D187_010406	3.472e-43	177.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria,2YYCQ@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
GDHHQS3_k127_7171524_22	234267.Acid_4440	5.67e-57	211.0	COG1073@1|root,COG1073@2|Bacteria,3Y91X@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7171524_53	1123258.AQXZ01000018_gene1035	5.802e-06	53.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
GDHHQS3_k127_7171524_44	926560.KE387023_gene2058	1.013e-19	102.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_7171524_51	649638.Trad_1397	1.082e-10	65.0	2EFYU@1|root,339R0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
GDHHQS3_k127_7171524_39	1379270.AUXF01000002_gene1580	4.109e-26	121.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_7171524_4	1192034.CAP_2342	4.921e-207	662.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_7171524_46	1122197.ATWI01000015_gene815	1.354e-16	91.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
GDHHQS3_k127_7171524_1	497964.CfE428DRAFT_2129	0.0	1334.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GDHHQS3_k127_7171524_13	243231.GSU2781	3.382e-90	318.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GDHHQS3_k127_7171524_56	326427.Cagg_1021	0.0001684	50.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
GDHHQS3_k127_7171524_8	1300345.LF41_901	1.742e-131	447.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XDED@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
GDHHQS3_k127_7171524_33	234267.Acid_7247	1.084e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_7171524_18	639030.JHVA01000001_gene1848	3.043e-61	236.0	COG1413@1|root,COG1413@2|Bacteria,3Y7PB@57723|Acidobacteria	57723|Acidobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_7171524_42	278963.ATWD01000001_gene2878	1.109e-21	111.0	COG1413@1|root,COG1413@2|Bacteria,3Y76M@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GDHHQS3_k127_7171524_37	604331.AUHY01000118_gene11	1.341e-29	122.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,Cupin_7
GDHHQS3_k127_7171524_10	314278.NB231_09083	8.227e-98	333.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RPAZ@1236|Gammaproteobacteria,1WWIG@135613|Chromatiales	135613|Chromatiales	G	PFAM Ribulose bisphosphate carboxylase large	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
GDHHQS3_k127_7171524_5	740709.A10D4_03105	4.291e-178	580.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QFCR@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GDHHQS3_k127_7171524_12	1121468.AUBR01000001_gene479	2.162e-90	330.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,42FJE@68295|Thermoanaerobacterales	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
GDHHQS3_k127_7171524_34	269799.Gmet_2576	3.651e-33	147.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria,43T4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_7171524_6	448385.sce2343	3.673e-136	457.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43A4R@68525|delta/epsilon subdivisions,2X23J@28221|Deltaproteobacteria,2YUTA@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
GDHHQS3_k127_7171524_41	1530186.JQEY01000004_gene2039	2.064e-25	121.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_7171524_17	1079986.JH164867_gene2680	3.304e-62	241.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
GDHHQS3_k127_7171524_47	862515.HMPREF0658_1399	6.37e-14	87.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
GDHHQS3_k127_7171524_30	797114.C475_01267	3.889e-37	160.0	COG0034@1|root,COG0367@1|root,arCOG00071@2157|Archaea,arCOG00093@2157|Archaea,2XV5E@28890|Euryarchaeota,23WDA@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_7171524_55	478741.JAFS01000002_gene10	0.0001125	48.0	2DRDY@1|root,33BC0@2|Bacteria	2|Bacteria	S	PFAM Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS3_k127_7181528_2	123899.JPQP01000022_gene3510	3.888e-22	112.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,3T1UM@506|Alcaligenaceae	28216|Betaproteobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_7181528_5	644968.DFW101_0661	1.316e-19	104.0	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GDHHQS3_k127_7181528_0	745776.DGo_CA0958	2.235e-146	479.0	COG0624@1|root,COG0624@2|Bacteria,1WIJT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_7181528_4	1297742.A176_07251	6.587e-20	104.0	2BVHD@1|root,32QVZ@2|Bacteria,1N6CE@1224|Proteobacteria,430V5@68525|delta/epsilon subdivisions,2X3NG@28221|Deltaproteobacteria,2YWNE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_7181528_7	1042877.GQS_01000	4.191e-12	81.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_7181528_6	1242864.D187_006518	2.003e-19	104.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GDHHQS3_k127_7181528_1	378806.STAUR_1023	5.882e-81	291.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales	28221|Deltaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_7181528_3	502025.Hoch_4926	6.99e-21	108.0	COG1266@1|root,COG1266@2|Bacteria,1RI59@1224|Proteobacteria,433F0@68525|delta/epsilon subdivisions,2WYHI@28221|Deltaproteobacteria,2Z276@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_7181528_8	1379698.RBG1_1C00001G1816	5.874e-09	68.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
GDHHQS3_k127_7243986_2	32042.PstZobell_01222	3.343e-100	363.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1Z160@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
GDHHQS3_k127_7243986_1	1192034.CAP_8502	1.395e-106	367.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,437G6@68525|delta/epsilon subdivisions,2X2NS@28221|Deltaproteobacteria,2YU1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_7243986_0	497964.CfE428DRAFT_6677	2.816e-131	439.0	COG2896@1|root,COG2896@2|Bacteria,46TG4@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Molybdenum Cofactor Synthesis C	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GDHHQS3_k127_7243986_3	1408419.JHYG01000015_gene2550	8.216e-59	228.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
GDHHQS3_k127_7243986_5	243159.AFE_1211	4.283e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
GDHHQS3_k127_7243986_7	1158762.KB898058_gene131	1.927e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
GDHHQS3_k127_7243986_6	1157634.KB912988_gene4384	6.55e-07	53.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_7278787_2	1267535.KB906767_gene3855	7.35e-110	378.0	COG0364@1|root,COG0364@2|Bacteria,3Y627@57723|Acidobacteria,2JKTN@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS3_k127_7278787_1	768671.ThimaDRAFT_3763	6.586e-120	434.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1WXUD@135613|Chromatiales	135613|Chromatiales	G	6-phosphogluconate dehydrogenase	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS3_k127_7278787_5	984962.XP_009541376.1	3.163e-30	138.0	COG0363@1|root,KOG3147@2759|Eukaryota,39U1J@33154|Opisthokonta,3NY1P@4751|Fungi,3UYNM@5204|Basidiomycota,225SZ@155619|Agaricomycetes,3H1CQ@355688|Agaricomycetes incertae sedis	4751|Fungi	G	6-phosphogluconolactonase	SOL1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006403,GO:0006405,GO:0006409,GO:0006611,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0015031,GO:0015833,GO:0015931,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0031503,GO:0033036,GO:0034613,GO:0034641,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046483,GO:0046496,GO:0046907,GO:0050657,GO:0050658,GO:0051031,GO:0051156,GO:0051168,GO:0051169,GO:0051179,GO:0051186,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0052689,GO:0055086,GO:0070727,GO:0071166,GO:0071426,GO:0071431,GO:0071702,GO:0071704,GO:0071705,GO:0072524,GO:0097064,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS3_k127_7278787_0	582515.KR51_00030710	0.0	1026.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
GDHHQS3_k127_7278787_8	391625.PPSIR1_36492	3.112e-19	103.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,P_proprotein
GDHHQS3_k127_7278787_9	472759.Nhal_1319	3.801e-14	87.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1WZJ1@135613|Chromatiales	135613|Chromatiales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GDHHQS3_k127_7278787_7	1340493.JNIF01000003_gene2485	6.678e-25	122.0	COG1596@1|root,COG1596@2|Bacteria,3Y7QA@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GDHHQS3_k127_7278787_4	1047013.AQSP01000112_gene392	1.011e-97	356.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
GDHHQS3_k127_7278787_6	1122599.AUGR01000016_gene2867	2.814e-27	130.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,1S34B@1236|Gammaproteobacteria,1XK8J@135619|Oceanospirillales	135619|Oceanospirillales	GM	capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7323756_0	234267.Acid_5940	2.567e-101	351.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_7323756_1	204669.Acid345_4118	1.022e-10	75.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_7381825_6	357808.RoseRS_3816	5.136e-35	154.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi,376D4@32061|Chloroflexia	32061|Chloroflexia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_8
GDHHQS3_k127_7381825_10	316275.VSAL_I2255	1.748e-07	61.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1S64I@1236|Gammaproteobacteria,1XWIN@135623|Vibrionales	135623|Vibrionales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	VP2042	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
GDHHQS3_k127_7381825_4	1123368.AUIS01000010_gene2383	2.663e-64	226.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,2NCNW@225057|Acidithiobacillales	225057|Acidithiobacillales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS3_k127_7381825_9	1479237.JMLY01000001_gene3330	2.334e-10	73.0	2C3KM@1|root,32UH0@2|Bacteria,1N3F2@1224|Proteobacteria,1S9U2@1236|Gammaproteobacteria,46B2R@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7381825_5	234267.Acid_0387	9.415e-39	164.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
GDHHQS3_k127_7381825_0	879212.DespoDRAFT_02586	8.36e-117	389.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MII7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_7381825_1	596152.DesU5LDRAFT_3141	4.246e-102	351.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2M7SW@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GDHHQS3_k127_7381825_2	243231.GSU0439	1.323e-80	294.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,43TYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_7381825_3	1175306.GWL_32430	1.224e-77	278.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
GDHHQS3_k127_7381825_7	1123508.JH636445_gene6656	4.239e-34	147.0	COG1917@1|root,COG1917@2|Bacteria,2J31X@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
GDHHQS3_k127_7381825_8	204669.Acid345_4118	1.087e-14	75.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_7474554_0	234267.Acid_7679	1.858e-74	261.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_7474554_1	1123256.KB907925_gene1157	1.532e-38	149.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1X6WU@135614|Xanthomonadales	135614|Xanthomonadales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
GDHHQS3_k127_7474554_2	1279019.ARQK01000043_gene2135	1.204e-18	91.0	2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,1SGQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
GDHHQS3_k127_7474554_3	1123023.JIAI01000001_gene7601	9.578e-08	55.0	COG1520@1|root,COG1520@2|Bacteria,2I5K6@201174|Actinobacteria	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
GDHHQS3_k127_7567336_0	321327.CYA_2657	4.195e-168	533.0	COG1899@1|root,COG1899@2|Bacteria,1GCEV@1117|Cyanobacteria,1H3XV@1129|Synechococcus	1117|Cyanobacteria	O	Hypusine is a modified amino acid found in eukarya and archaea, but as yet	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS3_k127_7567336_16	378806.STAUR_4666	3.04e-49	184.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
GDHHQS3_k127_7567336_7	414684.RC1_2755	2.275e-94	332.0	COG4111@1|root,COG4111@2|Bacteria,1MXHA@1224|Proteobacteria,2TQQU@28211|Alphaproteobacteria,2JQV4@204441|Rhodospirillales	204441|Rhodospirillales	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7567336_3	266779.Meso_2557	2.968e-134	437.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,43I9G@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GDHHQS3_k127_7567336_2	1121033.AUCF01000006_gene4257	6.202e-136	466.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,2JPUG@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_7567336_9	509190.Cseg_3424	5.731e-85	312.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,2KFMV@204458|Caulobacterales	204458|Caulobacterales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GDHHQS3_k127_7567336_5	1267533.KB906740_gene150	8.889e-99	335.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria,2JI3W@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS3_k127_7567336_4	472759.Nhal_3219	2.287e-121	406.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,1S03P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	(GMC) oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,GMC_oxred_C,Pyr_redox_2
GDHHQS3_k127_7567336_24	1549858.MC45_10480	2.045e-05	57.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GDHHQS3_k127_7567336_1	671143.DAMO_0098	2.427e-142	479.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_7567336_18	1131814.JAFO01000001_gene490	1.99e-46	186.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS3_k127_7567336_11	2045.KR76_18615	2.116e-69	244.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4DQM4@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GDHHQS3_k127_7567336_22	477228.YO5_01379	3.563e-07	62.0	COG0715@1|root,COG0715@2|Bacteria,1N40U@1224|Proteobacteria,1SG8D@1236|Gammaproteobacteria,1Z0AY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
GDHHQS3_k127_7567336_21	269799.Gmet_2096	7.814e-14	80.0	COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,42VN3@68525|delta/epsilon subdivisions,2WRDJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_7567336_12	349521.HCH_02499	2.194e-67	246.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales	135619|Oceanospirillales	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
GDHHQS3_k127_7567336_6	266117.Rxyl_2923	4.193e-96	334.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4CQPH@84995|Rubrobacteria	84995|Rubrobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS3_k127_7567336_14	1297742.A176_00502	4.394e-63	228.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
GDHHQS3_k127_7567336_19	314260.PB2503_10479	6.71e-43	163.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria,2UFEE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GDHHQS3_k127_7567336_8	240015.ACP_0506	1.308e-93	331.0	COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria,2JI9C@204432|Acidobacteriia	204432|Acidobacteriia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
GDHHQS3_k127_7567336_20	1446473.JHWH01000007_gene511	4.019e-23	109.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2PU9B@265|Paracoccus	28211|Alphaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS3_k127_7567336_15	234267.Acid_0264	8.722e-53	209.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
GDHHQS3_k127_7567336_13	234267.Acid_7185	4.89e-65	252.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7567336_17	639030.JHVA01000001_gene3442	9.458e-47	189.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_7567336_10	485913.Krac_2581	8.532e-75	271.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS3_k127_7668778_17	1267533.KB906733_gene3152	2.534e-05	52.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_7668778_0	234267.Acid_7035	4.705e-258	834.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_7668778_1	1385519.N801_15180	1.57e-183	588.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,4FK2A@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
GDHHQS3_k127_7668778_13	35754.JNYJ01000014_gene4729	1.691e-21	104.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4DE2T@85008|Micromonosporales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_7668778_4	330214.NIDE0547	1.515e-63	243.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GDHHQS3_k127_7668778_8	1121939.L861_18925	5.865e-40	159.0	2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,1SBBP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7668778_7	682795.AciX8_3169	8.943e-44	178.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
GDHHQS3_k127_7668778_14	234267.Acid_7037	3.925e-17	92.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
GDHHQS3_k127_7668778_5	251229.Chro_2479	1.903e-44	174.0	COG1442@1|root,COG1442@2|Bacteria,1GKCV@1117|Cyanobacteria,3VM7M@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
GDHHQS3_k127_7668778_12	1142394.PSMK_19720	6.085e-29	134.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7668778_15	1142394.PSMK_19720	2.975e-11	78.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_7668778_10	1142394.PSMK_19690	5.282e-34	147.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_7668778_9	1142394.PSMK_19710	1.207e-38	162.0	COG0438@1|root,COG0438@2|Bacteria,2J1BV@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_7668778_3	595536.ADVE02000001_gene481	2.074e-87	314.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2TSIG@28211|Alphaproteobacteria,36Z2V@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS3_k127_7668778_16	682795.AciX8_2720	4.508e-07	61.0	COG0500@1|root,COG0500@2|Bacteria,3Y4Q0@57723|Acidobacteria,2JJCW@204432|Acidobacteriia	204432|Acidobacteriia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GDHHQS3_k127_7668778_11	187272.Mlg_2478	9.934e-30	127.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS3_k127_7668778_2	1232410.KI421418_gene2202	2.779e-137	452.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,42N0R@68525|delta/epsilon subdivisions,2WMPF@28221|Deltaproteobacteria,43U7D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
GDHHQS3_k127_7668778_6	941449.dsx2_2908	6.128e-44	166.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MBDA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
GDHHQS3_k127_7745530_4	1227739.Hsw_2957	0.0003859	52.0	COG0457@1|root,COG0457@2|Bacteria,4PKS0@976|Bacteroidetes,47YHR@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7745530_3	1298867.AUES01000005_gene171	2.188e-10	72.0	COG3554@1|root,COG3554@2|Bacteria,1RHFQ@1224|Proteobacteria,2U9RI@28211|Alphaproteobacteria,3JU9E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7745530_0	379066.GAU_2338	2.302e-60	223.0	COG2972@1|root,COG2972@2|Bacteria,1ZURN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
GDHHQS3_k127_7745530_1	861299.J421_6004	3.141e-55	203.0	COG3279@1|root,COG3279@2|Bacteria,1ZUUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
GDHHQS3_k127_7745530_2	234267.Acid_1573	2.236e-22	110.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	MA20_35785	-	2.5.1.18	ko:K00799,ko:K04750	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1
GDHHQS3_k127_8019658_2	1305735.JAFT01000005_gene2644	8.226e-19	89.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria,2PCA3@252301|Oceanicola	28211|Alphaproteobacteria	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS3_k127_8019658_0	1108045.GORHZ_202_00100	4.352e-54	199.0	2931F@1|root,2ZQIQ@2|Bacteria,2IGSZ@201174|Actinobacteria,4GFTT@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8019658_1	204669.Acid345_4047	6.56e-51	195.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_8024952_0	278963.ATWD01000002_gene336	3.781e-265	833.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS3_k127_8024952_41	439235.Dalk_1042	3.437e-19	97.0	COG1216@1|root,COG4122@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,42R09@68525|delta/epsilon subdivisions,2WMWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GDHHQS3_k127_8024952_3	234267.Acid_6644	1.872e-146	488.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
GDHHQS3_k127_8024952_46	1047013.AQSP01000139_gene2383	1.387e-05	57.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516,ko:K05801	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DUF4388,DnaJ,DnaJ_C,TerB,WD40
GDHHQS3_k127_8024952_44	665029.EAMY_3112	6.521e-15	85.0	2DMTH@1|root,32TKP@2|Bacteria,1QKCC@1224|Proteobacteria,1TGYJ@1236|Gammaproteobacteria,3X7R1@551|Erwinia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8024952_28	96561.Dole_0590	1.461e-51	196.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2MICC@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM peptidase U61 LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
GDHHQS3_k127_8024952_32	903818.KI912268_gene762	1.367e-37	154.0	COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,cNMP_binding
GDHHQS3_k127_8024952_4	378806.STAUR_3943	9.748e-141	482.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,2YXV4@29|Myxococcales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS3_k127_8024952_36	1417296.U879_12375	9.661e-27	123.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8024952_6	648996.Theam_1168	4.044e-121	404.0	COG0180@1|root,COG0180@2|Bacteria,2G3J1@200783|Aquificae	200783|Aquificae	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS3_k127_8024952_30	243231.GSU1832	2.12e-41	166.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS3_k127_8024952_34	330214.NIDE1418	3.213e-36	157.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS3_k127_8024952_24	632292.Calhy_1192	2.387e-57	213.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_8024952_27	760568.Desku_1846	9.401e-53	195.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,261QH@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS3_k127_8024952_7	586416.GZ22_08820	1.904e-118	391.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_8024952_9	234267.Acid_3693	6.288e-109	389.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_8024952_22	383381.EH30_14285	6.888e-75	265.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
GDHHQS3_k127_8024952_1	1499967.BAYZ01000095_gene4092	1.453e-188	606.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Cytidylate_kin,LYTB,S1
GDHHQS3_k127_8024952_37	1267535.KB906767_gene253	1.977e-25	123.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GDHHQS3_k127_8024952_43	1267535.KB906767_gene2239	1.751e-17	87.0	2B6R1@1|root,31ZPU@2|Bacteria,3Y4VP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8024952_19	1297742.A176_02874	1.687e-87	303.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GDHHQS3_k127_8024952_5	234267.Acid_2355	6.961e-132	455.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_8024952_33	1123368.AUIS01000016_gene2521	7.871e-37	161.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SACF@1236|Gammaproteobacteria,2NBVJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
GDHHQS3_k127_8024952_31	292459.STH1337	4.633e-39	164.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GDHHQS3_k127_8024952_26	1236541.BALL01000021_gene2743	7.684e-53	194.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,2Q8NX@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Guanylate_kin
GDHHQS3_k127_8024952_49	90814.KL370892_gene2134	0.0009344	46.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,4618M@72273|Thiotrichales	72273|Thiotrichales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
GDHHQS3_k127_8024952_16	1384054.N790_12395	3.317e-92	320.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1X3EH@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS3_k127_8024952_23	404589.Anae109_1500	8.247e-61	222.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_8024952_15	357808.RoseRS_0699	1.693e-94	336.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia	32061|Chloroflexia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GDHHQS3_k127_8024952_12	941449.dsx2_1370	1.423e-102	350.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2M7V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_8024952_11	1144275.COCOR_04861	6.547e-107	371.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_8024952_29	1131269.AQVV01000010_gene2437	2.37e-48	195.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
GDHHQS3_k127_8024952_45	926566.Terro_0428	1.832e-08	64.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4TB@57723|Acidobacteria,2JJHG@204432|Acidobacteriia	204432|Acidobacteriia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS3_k127_8024952_25	1047013.AQSP01000042_gene408	1.933e-56	214.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
GDHHQS3_k127_8024952_14	794903.OPIT5_29465	3.318e-95	319.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8024952_17	1384056.N787_08305	1.42e-90	322.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1X4UK@135614|Xanthomonadales	135614|Xanthomonadales	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8024952_48	1282356.H045_08365	4.851e-05	46.0	COG0358@1|root,COG0358@2|Bacteria,1MWSP@1224|Proteobacteria,1RYXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_N,zf-CHC2
GDHHQS3_k127_8024952_35	204669.Acid345_0553	5.906e-36	142.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
GDHHQS3_k127_8024952_42	290397.Adeh_2980	1.058e-17	93.0	COG4235@1|root,COG4235@2|Bacteria,1RITV@1224|Proteobacteria,43CCM@68525|delta/epsilon subdivisions,2X7NI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
GDHHQS3_k127_8024952_2	1267535.KB906767_gene823	7.935e-154	522.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria,2JI1K@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS3_k127_8024952_10	1234364.AMSF01000027_gene3482	3.095e-107	359.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1X3I8@135614|Xanthomonadales	135614|Xanthomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
GDHHQS3_k127_8024952_13	1123250.KB908379_gene1020	8.53e-96	337.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H201@909932|Negativicutes	909932|Negativicutes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_8024952_47	1267534.KB906754_gene3036	3.841e-05	57.0	COG1934@1|root,COG1934@2|Bacteria,3Y388@57723|Acidobacteria,2JI5E@204432|Acidobacteriia	204432|Acidobacteriia	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
GDHHQS3_k127_8024952_18	1340493.JNIF01000003_gene2837	2.277e-89	312.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_8024952_8	338963.Pcar_1938	4.092e-110	383.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GDHHQS3_k127_8024952_39	1121918.ARWE01000001_gene1885	3.969e-21	98.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,43SM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
GDHHQS3_k127_8024952_20	290397.Adeh_0146	2.983e-85	297.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
GDHHQS3_k127_8024952_21	204669.Acid345_3782	1.236e-76	266.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
GDHHQS3_k127_8024952_38	1280950.HJO_07542	4.301e-22	106.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,43XZ4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
GDHHQS3_k127_8024952_40	1121013.P873_02760	5.722e-20	96.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1X7PU@135614|Xanthomonadales	135614|Xanthomonadales	G	phosphocarrier protein HPr	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_8079514_0	945713.IALB_1070	2.184e-235	740.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS3_k127_8079514_4	591167.Sfla_6635	8.743e-46	170.0	28NYH@1|root,2ZBVN@2|Bacteria,2H6WC@201174|Actinobacteria	201174|Actinobacteria	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
GDHHQS3_k127_8079514_9	338963.Pcar_1696	4.334e-05	56.0	294M8@1|root,34B0H@2|Bacteria,1P2RM@1224|Proteobacteria,43174@68525|delta/epsilon subdivisions,2WWJZ@28221|Deltaproteobacteria,43VJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GDHHQS3_k127_8079514_6	498848.TaqDRAFT_4817	8.388e-19	101.0	COG0739@1|root,COG0739@2|Bacteria,1WIP1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_8079514_3	1380394.JADL01000003_gene4922	1.577e-67	240.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,2JQBG@204441|Rhodospirillales	28211|Alphaproteobacteria	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS3_k127_8079514_2	357808.RoseRS_2761	1.219e-96	348.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
GDHHQS3_k127_8079514_1	1288826.MSNKSG1_18230	4.866e-123	409.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,1RRTH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
GDHHQS3_k127_8079514_7	365046.Rta_08670	1.141e-16	89.0	COG3937@1|root,COG3937@2|Bacteria,1RIXG@1224|Proteobacteria,2VT1J@28216|Betaproteobacteria,4ADWD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM poly granule associated family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
GDHHQS3_k127_8079514_5	1089550.ATTH01000001_gene1118	5.246e-31	128.0	COG5394@1|root,COG5394@2|Bacteria,4PF5Z@976|Bacteroidetes,1FK70@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
GDHHQS3_k127_8079514_8	240015.ACP_0948	1.096e-07	60.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria,2JJRG@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
GDHHQS3_k127_8111999_4	1111732.AZOD01000005_gene876	8.464e-140	450.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1X3NI@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS3_k127_8111999_8	1380394.JADL01000010_gene4230	2.778e-13	72.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,2JU60@204441|Rhodospirillales	204441|Rhodospirillales	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8111999_7	1047013.AQSP01000138_gene1074	7.392e-18	88.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS3_k127_8111999_5	234267.Acid_4535	2.883e-96	347.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_8111999_3	1239962.C943_03564	1.359e-144	471.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_8111999_0	497964.CfE428DRAFT_4648	2.085e-195	644.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CBS,GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_8111999_1	234267.Acid_7636	4.331e-182	611.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_8111999_2	1267534.KB906760_gene1549	1.763e-153	537.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_8111999_6	1379698.RBG1_1C00001G0607	1.707e-91	325.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
GDHHQS3_k127_8169332_86	1125863.JAFN01000001_gene3374	1.884e-19	103.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42P1P@68525|delta/epsilon subdivisions,2WJ99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TAT_signal,TPR_16,TPR_19
GDHHQS3_k127_8169332_101	743721.Psesu_1724	0.0003354	48.0	2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,1SH79@1236|Gammaproteobacteria,1X88B@135614|Xanthomonadales	135614|Xanthomonadales	S	polyhydroxyalkanoic acid	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
GDHHQS3_k127_8169332_19	1242864.D187_008909	2.687e-130	431.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_8169332_22	502025.Hoch_5542	2.019e-114	383.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,2Z11I@29|Myxococcales	28221|Deltaproteobacteria	M	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
GDHHQS3_k127_8169332_67	1463936.JOJI01000059_gene6084	3.038e-34	144.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
GDHHQS3_k127_8169332_79	1499967.BAYZ01000023_gene264	8.696e-23	109.0	COG1193@1|root,COG1193@2|Bacteria,2NRN7@2323|unclassified Bacteria	2|Bacteria	L	Smr domain	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GDHHQS3_k127_8169332_90	1128421.JAGA01000002_gene21	8.476e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS3_k127_8169332_15	634452.APA01_00440	1.648e-148	481.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2JPIZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS3_k127_8169332_39	1356854.N007_02840	1.472e-68	248.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,2785S@186823|Alicyclobacillaceae	91061|Bacilli	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS3_k127_8169332_82	479434.Sthe_2558	3.862e-21	109.0	COG1971@1|root,COG5305@1|root,COG1971@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp,PMT_2
GDHHQS3_k127_8169332_30	714943.Mucpa_4497	2.671e-88	297.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,1IRP2@117747|Sphingobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8169332_28	330214.NIDE0344	1.498e-99	339.0	COG0714@1|root,COG0714@2|Bacteria,3J0WQ@40117|Nitrospirae	40117|Nitrospirae	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_8169332_68	330214.NIDE0343	1.304e-32	145.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_8169332_57	1192034.CAP_1666	1.484e-44	185.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
GDHHQS3_k127_8169332_102	585425.KR52_07115	0.00051	51.0	COG1525@1|root,COG1525@2|Bacteria,1GRFD@1117|Cyanobacteria,1H0X5@1129|Synechococcus	1117|Cyanobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	-	-	-	-	-	-	-	-	-	-	SNase
GDHHQS3_k127_8169332_11	573370.DMR_42330	7.898e-153	491.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2M98D@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GDHHQS3_k127_8169332_100	395019.Bmul_3791	0.0001583	53.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria,1K8AF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_8169332_84	234267.Acid_1797	2.895e-20	99.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
GDHHQS3_k127_8169332_38	861299.J421_3449	4.62e-76	264.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_8169332_80	1187851.A33M_0934	1.731e-22	113.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,2U7JN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_36	886293.Sinac_6613	7.115e-78	274.0	COG1216@1|root,COG1216@2|Bacteria,2IZFD@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8169332_2	1121920.AUAU01000013_gene1698	2.022e-285	895.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
GDHHQS3_k127_8169332_1	525368.HMPREF0591_0942	0.0	1125.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0016829,GO:0016830,GO:0016833	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
GDHHQS3_k127_8169332_46	1267535.KB906767_gene4480	3.324e-59	214.0	COG4430@1|root,COG4430@2|Bacteria,3Y5HF@57723|Acidobacteria,2JMZY@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_8169332_95	1123377.AUIV01000001_gene915	7.154e-10	62.0	2ANYG@1|root,2ZGFF@2|Bacteria,1QEQI@1224|Proteobacteria,1TBIU@1236|Gammaproteobacteria,1X94U@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_0	525909.Afer_1020	0.0	1427.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS3_k127_8169332_10	1304275.C41B8_18181	1.08e-187	600.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
GDHHQS3_k127_8169332_70	1210884.HG799469_gene13988	1.096e-30	128.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	MA20_24420	-	-	ko:K06889,ko:K07000	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,UPF0227
GDHHQS3_k127_8169332_21	204669.Acid345_0197	2.172e-118	422.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_16	1453501.JELR01000002_gene593	3.95e-143	466.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,465BJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_8169332_6	1540221.JQNI01000002_gene1832	2.002e-239	768.0	COG0466@1|root,COG0466@2|Bacteria,1WISX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_8169332_47	861299.J421_6025	3.459e-58	212.0	COG0730@1|root,COG0730@2|Bacteria,1ZTJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_8169332_94	756272.Plabr_3400	2.777e-10	71.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
GDHHQS3_k127_8169332_61	29306.JOBE01000021_gene462	1.003e-40	161.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_8169332_54	215803.DB30_2834	2.547e-47	178.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2X5P2@28221|Deltaproteobacteria,2Z36K@29|Myxococcales	28221|Deltaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GDHHQS3_k127_8169332_72	1340493.JNIF01000003_gene4229	1.551e-30	138.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
GDHHQS3_k127_8169332_29	1283299.AUKG01000001_gene1980	6.953e-96	331.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CRTD@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS3_k127_8169332_91	1121938.AUDY01000016_gene3001	8.175e-13	78.0	COG1280@1|root,COG1280@2|Bacteria,1VAZK@1239|Firmicutes,4HMYY@91061|Bacilli,3NG20@45667|Halobacillus	91061|Bacilli	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS3_k127_8169332_55	640081.Dsui_1522	3.748e-47	192.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GDHHQS3_k127_8169332_27	404589.Anae109_3188	9.407e-102	344.0	COG0642@1|root,COG2205@2|Bacteria,1R8JB@1224|Proteobacteria	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GDHHQS3_k127_8169332_7	477974.Daud_0168	4.529e-219	695.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GDHHQS3_k127_8169332_87	1379270.AUXF01000004_gene2937	2.464e-18	92.0	2E902@1|root,3339H@2|Bacteria,1ZV2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_65	443144.GM21_1286	9.785e-39	146.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,42U4W@68525|delta/epsilon subdivisions,2WQ9S@28221|Deltaproteobacteria,43VBS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GDHHQS3_k127_8169332_34	880072.Desac_0027	1.537e-84	301.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_8169332_97	390989.JOEG01000001_gene5125	7.184e-06	57.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4DEMP@85008|Micromonosporales	201174|Actinobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS3_k127_8169332_58	1121920.AUAU01000018_gene1797	5.147e-44	175.0	COG0477@1|root,COG2814@2|Bacteria,3Y95Q@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8169332_3	926550.CLDAP_35340	2.021e-277	907.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2G5JU@200795|Chloroflexi	2|Bacteria	C	PFAM Transketolase central region	pdhB	-	1.2.4.4,2.2.1.1	ko:K00615,ko:K11381	ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00036,M00165,M00167	R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_8169332_13	1206735.BAGG01000021_gene1010	7.79e-151	486.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4FXV6@85025|Nocardiaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_8169332_32	483219.LILAB_32755	6.299e-86	297.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
GDHHQS3_k127_8169332_88	1123508.JH636441_gene3434	1.632e-14	86.0	28MEZ@1|root,2ZASI@2|Bacteria,2IYHZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_75	1379270.AUXF01000005_gene665	5.191e-28	132.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_8169332_78	204669.Acid345_1523	9.062e-24	110.0	COG1278@1|root,COG1278@2|Bacteria,3Y57P@57723|Acidobacteria,2JJS8@204432|Acidobacteriia	204432|Acidobacteriia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_8169332_31	1123242.JH636435_gene833	1.4e-86	316.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GDHHQS3_k127_8169332_26	1340493.JNIF01000004_gene526	5.953e-103	370.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
GDHHQS3_k127_8169332_43	1415780.JPOG01000001_gene2544	1.258e-62	230.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1X36Q@135614|Xanthomonadales	135614|Xanthomonadales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS3_k127_8169332_73	243231.GSU1429	6.047e-30	135.0	COG0591@1|root,COG2203@1|root,COG2208@1|root,COG0591@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,43TB9@69541|Desulfuromonadales	28221|Deltaproteobacteria	EKT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
GDHHQS3_k127_8169332_59	429009.Adeg_0447	4.253e-42	160.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS3_k127_8169332_89	502025.Hoch_1932	2.697e-14	79.0	2A7EC@1|root,30WBT@2|Bacteria,1PDJ7@1224|Proteobacteria,43E64@68525|delta/epsilon subdivisions,2WZUI@28221|Deltaproteobacteria,2Z2SD@29|Myxococcales	28221|Deltaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
GDHHQS3_k127_8169332_20	1458275.AZ34_08905	7.68e-123	407.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,4AIFH@80864|Comamonadaceae	28216|Betaproteobacteria	P	Divalent cation transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GDHHQS3_k127_8169332_35	1210884.HG799464_gene10754	2.348e-82	280.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_8169332_5	671143.DAMO_1445	5.628e-241	792.0	COG0417@1|root,COG1205@1|root,COG0417@2|Bacteria,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DNA_pol_B,DNA_pol_B_exo1,DUF1998,Helicase_C
GDHHQS3_k127_8169332_81	1089544.KB912942_gene3115	9.725e-22	99.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS3_k127_8169332_98	498848.TaqDRAFT_4507	1.259e-05	51.0	COG4423@1|root,COG4423@2|Bacteria,1WKIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rv0623-like transcription factor	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
GDHHQS3_k127_8169332_45	314345.SPV1_05597	1.823e-59	222.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS3_k127_8169332_9	1121930.AQXG01000009_gene258	8.24e-191	607.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,1IVJC@117747|Sphingobacteriia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
GDHHQS3_k127_8169332_33	1144275.COCOR_07790	2.707e-85	295.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,433YB@68525|delta/epsilon subdivisions,2X423@28221|Deltaproteobacteria,2YY0M@29|Myxococcales	28221|Deltaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
GDHHQS3_k127_8169332_40	502025.Hoch_6599	5.153e-68	245.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase chorismate mutase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
GDHHQS3_k127_8169332_23	1267535.KB906767_gene2627	1.466e-111	378.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_8169332_96	378806.STAUR_1650	3.767e-09	59.0	2AR7A@1|root,31GH0@2|Bacteria,1QAE5@1224|Proteobacteria,4350V@68525|delta/epsilon subdivisions,2X942@28221|Deltaproteobacteria,2Z1SN@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
GDHHQS3_k127_8169332_17	330214.NIDE0473	3.173e-135	441.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
GDHHQS3_k127_8169332_25	330214.NIDE0474	5.817e-107	376.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_8169332_56	326427.Cagg_0668	1.019e-46	187.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
GDHHQS3_k127_8169332_51	880073.Calab_0541	8.39e-53	194.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
GDHHQS3_k127_8169332_69	1232437.KL661988_gene214	9.188e-32	129.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MKW0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS3_k127_8169332_71	522373.Smlt0739	1.363e-30	133.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,1X77S@135614|Xanthomonadales	135614|Xanthomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS3_k127_8169332_62	232346.JHQL01000003_gene422	2.485e-40	153.0	2CNK3@1|root,31TH7@2|Bacteria,1R38H@1224|Proteobacteria,1S7X7@1236|Gammaproteobacteria,1XKY6@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
GDHHQS3_k127_8169332_53	234267.Acid_4772	1.932e-49	179.0	COG1695@1|root,COG1695@2|Bacteria,3Y7WH@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_8169332_12	234267.Acid_7706	2.606e-152	518.0	COG0577@1|root,COG0577@2|Bacteria	234267.Acid_7706|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8169332_49	1267533.KB906741_gene406	2.773e-55	204.0	2B4PH@1|root,31XFS@2|Bacteria,3Y8X7@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_8169332_92	358396.C445_20865	1.699e-11	73.0	COG1917@1|root,arCOG02994@2157|Archaea,2Y07C@28890|Euryarchaeota,23Y8S@183963|Halobacteria	183963|Halobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_8169332_8	1144275.COCOR_05413	1.653e-204	666.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria	1224|Proteobacteria	U	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_8169332_24	246197.MXAN_1283	1.811e-111	383.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_8169332_18	1379698.RBG1_1C00001G0513	1.542e-131	434.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GDHHQS3_k127_8169332_52	460265.Mnod_5856	1.559e-51	189.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,1JS0W@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM beta-lactamase domain protein	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_8169332_37	1123392.AQWL01000005_gene3118	1.3e-77	274.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,1KRID@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_8169332_66	1121468.AUBR01000016_gene2351	2.161e-35	147.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
GDHHQS3_k127_8169332_74	1121920.AUAU01000011_gene189	3.524e-29	136.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
GDHHQS3_k127_8169332_42	1121920.AUAU01000008_gene1664	1.422e-63	222.0	COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_8169332_14	1121403.AUCV01000026_gene2342	7.997e-151	496.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MIC7@213118|Desulfobacterales	68525|delta/epsilon subdivisions	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS3_k127_8169332_64	765869.BDW_11300	5.915e-39	161.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2MTE2@213481|Bdellovibrionales,2WRSP@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
GDHHQS3_k127_8169332_60	1125863.JAFN01000001_gene723	7.776e-42	178.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS3_k127_8169332_44	234267.Acid_5477	1.054e-60	216.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria	57723|Acidobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_8169332_41	243090.RB13211	4.846e-67	256.0	COG0463@1|root,COG1807@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,2IZ8J@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 39	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
GDHHQS3_k127_8169332_77	398512.JQKC01000037_gene4525	6.89e-26	112.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,3WQ51@541000|Ruminococcaceae	186801|Clostridia	S	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_8169332_63	768706.Desor_3537	4.778e-40	163.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_8169332_83	1267535.KB906767_gene784	4.865e-21	105.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_8169332_50	504472.Slin_2494	1.487e-54	203.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_8169332_4	211114.JOEF01000002_gene4202	1.666e-252	793.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4DXF9@85010|Pseudonocardiales	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS3_k127_8169332_48	512565.AMIS_75720	3.44e-57	199.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DC7Q@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS3_k127_8172986_31	309801.trd_1178	6.458e-41	157.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_8172986_4	504472.Slin_2318	9.454e-133	440.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_8172986_6	861299.J421_2199	8.701e-118	415.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_2199|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8172986_38	926566.Terro_3025	7.978e-31	134.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_8172986_66	794903.OPIT5_16565	0.0001792	48.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
GDHHQS3_k127_8172986_52	1122603.ATVI01000009_gene2529	1.754e-17	92.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria,1X899@135614|Xanthomonadales	135614|Xanthomonadales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_8172986_1	869210.Marky_1232	2.737e-283	919.0	COG0060@1|root,COG0060@2|Bacteria,1WI61@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS3_k127_8172986_28	485913.Krac_8693	4.979e-47	184.0	COG0596@1|root,COG0596@2|Bacteria,2G7BF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_8172986_29	1121033.AUCF01000019_gene3730	4.892e-44	169.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2U7NP@28211|Alphaproteobacteria,2JS9M@204441|Rhodospirillales	204441|Rhodospirillales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS3_k127_8172986_47	1121406.JAEX01000006_gene2174	1.108e-22	103.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,42S60@68525|delta/epsilon subdivisions,2WRAR@28221|Deltaproteobacteria,2MBDR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
GDHHQS3_k127_8172986_50	204669.Acid345_4135	9.127e-20	103.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria,2JK2N@204432|Acidobacteriia	204432|Acidobacteriia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GDHHQS3_k127_8172986_40	1123376.AUIU01000003_gene1638	6.024e-28	129.0	COG0457@1|root,COG1066@1|root,COG5416@1|root,COG0457@2|Bacteria,COG1066@2|Bacteria,COG5416@2|Bacteria,3J1FE@40117|Nitrospirae	40117|Nitrospirae	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8172986_67	483219.LILAB_21710	0.0003537	55.0	COG1466@1|root,COG1466@2|Bacteria,1RAEB@1224|Proteobacteria,42R0X@68525|delta/epsilon subdivisions,2WMQJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS3_k127_8172986_25	903818.KI912268_gene1040	1.305e-49	191.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
GDHHQS3_k127_8172986_37	1203605.HMPREF1531_00423	5.887e-31	127.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4DNI0@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
GDHHQS3_k127_8172986_7	1267535.KB906767_gene3449	1.962e-117	407.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
GDHHQS3_k127_8172986_2	234267.Acid_0040	1.78e-166	535.0	COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8172986_58	1382356.JQMP01000003_gene2143	4.674e-11	74.0	COG1266@1|root,COG1266@2|Bacteria,2G9FI@200795|Chloroflexi,27YGJ@189775|Thermomicrobia	189775|Thermomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_8172986_45	866536.Belba_1006	7.415e-24	109.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GDHHQS3_k127_8172986_30	378806.STAUR_7589	3.346e-41	154.0	COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GDHHQS3_k127_8172986_21	760568.Desku_1929	6.563e-66	236.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,2606Y@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_8172986_61	1304872.JAGC01000009_gene1166	4.132e-06	60.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria,2M93I@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_8172986_22	1125863.JAFN01000001_gene3143	9.205e-64	248.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8172986_9	1125863.JAFN01000001_gene1632	2.033e-112	387.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42Z38@68525|delta/epsilon subdivisions,2X5H0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_8172986_8	1267535.KB906767_gene5241	1.711e-113	393.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_8172986_42	891968.Anamo_0561	4.255e-26	127.0	COG4942@1|root,COG4942@2|Bacteria,3T9S7@508458|Synergistetes	508458|Synergistetes	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS3_k127_8172986_49	1120983.KB894572_gene3213	3.83e-21	107.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,1JNEG@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS3_k127_8172986_27	1479238.JQMZ01000001_gene1827	3.848e-47	181.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria,43ZVG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
GDHHQS3_k127_8172986_48	1150621.SMUL_1240	2.686e-21	100.0	COG3744@1|root,COG3744@2|Bacteria,1RJXF@1224|Proteobacteria,431F2@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_8172986_65	933262.AXAM01000024_gene714	9.549e-05	48.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_8172986_60	1443665.JACA01000026_gene3512	2.613e-06	56.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia,2YIK3@290174|Aquimarina	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_8172986_10	402881.Plav_1394	3.614e-111	393.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,1JN72@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	FtsX-like permease family	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8172986_19	1267533.KB906742_gene739	2.036e-71	254.0	COG4181@1|root,COG4181@2|Bacteria,3Y3RU@57723|Acidobacteria,2JI42@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8172986_26	292459.STH1021	3.585e-49	186.0	COG2755@1|root,COG2755@2|Bacteria,1UFZN@1239|Firmicutes,24V88@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_8172986_20	1123060.JONP01000015_gene4420	3.333e-71	250.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales	204441|Rhodospirillales	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
GDHHQS3_k127_8172986_68	1142394.PSMK_21090	0.0006183	48.0	2EAFJ@1|root,334IY@2|Bacteria,2J12W@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
GDHHQS3_k127_8172986_63	529818.AMSG_12184T0	2.725e-05	57.0	COG0457@1|root,KOG1470@1|root,KOG1129@2759|Eukaryota,KOG1470@2759|Eukaryota	2759|Eukaryota	E	intermembrane phospholipid transfer	BBS8	-	-	ko:K16781	-	-	-	-	ko00000,ko03036	-	-	-	CRAL_TRIO,TPR_1,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_8172986_53	1297742.A176_02895	1.956e-17	95.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS3_k127_8172986_0	1267535.KB906767_gene2802	1.078e-293	915.0	COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia	204432|Acidobacteriia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_8172986_43	1047013.AQSP01000077_gene2268	2.181e-25	109.0	COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
GDHHQS3_k127_8172986_34	868864.Dester_1497	4.543e-38	153.0	COG1484@1|root,COG1484@2|Bacteria,2G47F@200783|Aquificae	200783|Aquificae	L	DNA replication protein DnaC	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS3_k127_8172986_23	1121920.AUAU01000015_gene1127	3.659e-63	243.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
GDHHQS3_k127_8172986_15	671143.DAMO_3032	5.626e-94	316.0	COG0861@1|root,COG0861@2|Bacteria,2NQFQ@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
GDHHQS3_k127_8172986_17	1234364.AMSF01000037_gene208	1.375e-76	282.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,1RS8B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS3_k127_8172986_3	682795.AciX8_2100	1.885e-142	461.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8172986_46	1449976.KALB_6754	9.559e-23	112.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4E0FQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS3_k127_8172986_13	1121920.AUAU01000036_gene1117	2.169e-94	322.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria	57723|Acidobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,Glyoxalase_4
GDHHQS3_k127_8172986_36	523850.TON_1074	5.31e-35	150.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GDHHQS3_k127_8172986_57	903818.KI912268_gene1428	3.53e-12	78.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8172986_12	765914.ThisiDRAFT_1997	4.132e-101	341.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1WXI6@135613|Chromatiales	135613|Chromatiales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GDHHQS3_k127_8172986_39	671143.DAMO_1656	8.331e-29	131.0	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8172986_14	1144275.COCOR_02616	2.923e-94	337.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2YYSC@29|Myxococcales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
GDHHQS3_k127_8172986_62	469383.Cwoe_2923	9.193e-06	59.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8172986_5	1192034.CAP_5545	5.413e-125	407.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS3_k127_8172986_32	234267.Acid_4549	9.882e-41	162.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8172986_16	1125863.JAFN01000001_gene2814	7.627e-91	304.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_8172986_33	573065.Astex_0126	1.318e-40	154.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
GDHHQS3_k127_8172986_35	697282.Mettu_0021	1.761e-37	155.0	COG0834@1|root,COG2202@1|root,COG5001@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1SKBG@1236|Gammaproteobacteria,1XDV3@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,SBP_bac_3
GDHHQS3_k127_8172986_51	1408813.AYMG01000007_gene4306	6.509e-19	94.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1IS3J@117747|Sphingobacteriia	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	-	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
GDHHQS3_k127_8172986_41	1487923.DP73_14315	7.129e-27	118.0	COG4636@1|root,COG4636@2|Bacteria,1V3G7@1239|Firmicutes,24H2Z@186801|Clostridia,266ZP@186807|Peptococcaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Uma2
GDHHQS3_k127_8172986_44	795359.TOPB45_1024	4.718e-24	112.0	COG2823@1|root,COG2823@2|Bacteria,2GHZQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	bacterial OsmY and nodulation domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS3_k127_8172986_24	247633.GP2143_09435	5.363e-63	235.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,1SJUT@1236|Gammaproteobacteria,1J957@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8172986_11	1183438.GKIL_4354	3.65e-105	373.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8172986_18	1267535.KB906767_gene4864	6.965e-75	261.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.1,4.2.1.103	ko:K01239,ko:K02855,ko:K07506,ko:K18199	ko00230,ko00760,ko00930,ko01100,map00230,map00760,map00930,map01100	-	R01245,R01273,R01677,R01770,R02143,R05771	RC00033,RC00063,RC00122,RC00318,RC00485,RC01467	ko00000,ko00001,ko01000,ko01002,ko03000	-	-	-	AraC_binding_2,HTH_18
GDHHQS3_k127_8172986_56	204669.Acid345_2760	6.692e-15	81.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_8172986_55	926566.Terro_3400	2.745e-16	94.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GDHHQS3_k127_8172986_59	1265503.KB905163_gene2061	9.635e-09	69.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1THKF@1236|Gammaproteobacteria,2Q74Z@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
GDHHQS3_k127_8201840_1	697281.Mahau_1084	7.222e-39	150.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS3_k127_8201840_0	234267.Acid_2671	2.525e-190	617.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,3Y7VX@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
GDHHQS3_k127_8226708_11	485913.Krac_2435	2.117e-70	245.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_8226708_0	204669.Acid345_3065	1.234e-188	610.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
GDHHQS3_k127_8226708_1	1442599.JAAN01000031_gene1437	1.088e-159	513.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3AN@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_8226708_16	1123400.KB904791_gene61	3.099e-26	110.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_8226708_9	903818.KI912268_gene2024	1.595e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	57723|Acidobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_8226708_7	1232410.KI421413_gene692	5.228e-86	299.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS3_k127_8226708_6	1121472.AQWN01000002_gene2329	1.05e-94	333.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS3_k127_8226708_18	1382359.JIAL01000001_gene525	4.288e-22	96.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JJZ9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS3_k127_8226708_19	240015.ACP_1927	2.268e-21	100.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria,2JJ8Y@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS3_k127_8226708_10	383372.Rcas_0218	1.02e-70	259.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi,3755I@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GDHHQS3_k127_8226708_5	326427.Cagg_2454	5.271e-111	375.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_8226708_13	479434.Sthe_1154	2.486e-55	208.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,27Y1R@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8226708_12	926550.CLDAP_10380	1.482e-57	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8226708_8	644282.Deba_0611	1.866e-84	307.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8226708_2	1499967.BAYZ01000017_gene6221	2.635e-133	441.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_8226708_4	1485544.JQKP01000001_gene1242	1.553e-112	379.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,44V1C@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_8226708_14	215803.DB30_6849	8.2e-34	150.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_8226708_3	243231.GSU1881	1.716e-129	435.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,43TR7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
GDHHQS3_k127_8226708_17	795666.MW7_0286	3.579e-24	104.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,1K8I2@119060|Burkholderiaceae	28216|Betaproteobacteria	G	phosphocarrier, HPr family	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_8226708_15	1047013.AQSP01000135_gene1606	1.912e-30	126.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
GDHHQS3_k127_8287449_15	926550.CLDAP_14210	1.265e-124	401.0	COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi	200795|Chloroflexi	O	PFAM deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GDHHQS3_k127_8287449_28	557599.MKAN_19100	1.712e-35	140.0	COG2346@1|root,COG2346@2|Bacteria,2IFYB@201174|Actinobacteria,23E5N@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
GDHHQS3_k127_8287449_26	398578.Daci_5373	3.394e-43	165.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,4ACFV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
GDHHQS3_k127_8287449_13	861299.J421_3595	1.876e-126	423.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_8287449_18	1379270.AUXF01000002_gene1363	2.103e-107	381.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
GDHHQS3_k127_8287449_14	234267.Acid_6967	3.807e-125	407.0	COG1131@1|root,COG1131@2|Bacteria,3Y78D@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8287449_24	1267534.KB906755_gene4573	5.595e-74	256.0	COG0842@1|root,COG0842@2|Bacteria,3Y6GQ@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_8287449_20	685778.AORL01000010_gene2565	3.449e-95	324.0	COG1073@1|root,COG1073@2|Bacteria,1R67P@1224|Proteobacteria,2U3D5@28211|Alphaproteobacteria,2K2QV@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS3_k127_8287449_19	671143.DAMO_0747	1.59e-105	361.0	COG0022@1|root,COG0022@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_8287449_21	861299.J421_3598	2.537e-94	321.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_8287449_7	1278073.MYSTI_03731	7.296e-160	524.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_8287449_35	1299327.I546_3665	2.542e-07	64.0	2CDGH@1|root,348SI@2|Bacteria,2GZQG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8287449_3	234267.Acid_5749	3.298e-173	574.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_37	1121861.KB899914_gene2008	1.532e-06	61.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,2UKQG@28211|Alphaproteobacteria,2JXR3@204441|Rhodospirillales	204441|Rhodospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_8287449_30	656024.FsymDg_2935	4.938e-26	115.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_8287449_32	419947.MRA_2623A	1.824e-20	93.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8287449_34	502025.Hoch_1577	4.592e-08	62.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8287449_38	502025.Hoch_1577	0.000125	50.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8287449_23	234267.Acid_7680	8.356e-82	287.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_1	234267.Acid_5749	7.303e-178	589.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_22	395961.Cyan7425_2945	1.124e-91	331.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GDHHQS3_k127_8287449_9	1279009.ADICEAN_03451	5.895e-154	504.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47MZ0@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_8287449_12	1384056.N787_06630	1.891e-127	421.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GDHHQS3_k127_8287449_31	448385.sce6459	1.591e-24	118.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_8287449_17	234267.Acid_5749	7.677e-109	385.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_29	419947.MRA_2578	1.322e-32	134.0	COG2402@1|root,COG2402@2|Bacteria,2H9NW@201174|Actinobacteria	201174|Actinobacteria	S	toxic component of a	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_8287449_5	502025.Hoch_1577	2.946e-162	546.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8287449_11	234267.Acid_5749	1.358e-135	465.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_6	234267.Acid_5749	4.296e-160	537.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_8	502025.Hoch_1577	2.549e-154	520.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8287449_33	460265.Mnod_2856	1.899e-14	75.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2U6NS@28211|Alphaproteobacteria,1JRFZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GDHHQS3_k127_8287449_16	204669.Acid345_4390	9.389e-111	392.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GDHHQS3_k127_8287449_0	234267.Acid_5749	9.691e-181	599.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_2	234267.Acid_3938	2.341e-173	576.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_10	204669.Acid345_0770	2.747e-137	471.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_8287449_25	234267.Acid_7680	2.224e-60	218.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_4	234267.Acid_5749	6.789e-172	582.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8287449_27	234267.Acid_5940	1.198e-40	161.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_8355973_4	445970.ALIPUT_01475	2.397e-30	124.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,2FQ2Q@200643|Bacteroidia,22U2S@171550|Rikenellaceae	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_8355973_2	204669.Acid345_2431	1.528e-47	186.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_8355973_1	338966.Ppro_2693	4.374e-59	214.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8355973_7	195522.BD01_0726	0.0006266	52.0	COG0515@1|root,COG3889@1|root,arCOG03264@1|root,arCOG01672@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2Y2TW@28890|Euryarchaeota,243EY@183968|Thermococci	183968|Thermococci	E	solute binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_8355973_5	1380346.JNIH01000005_gene3168	5.986e-21	99.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GDHHQS3_k127_8355973_6	1122947.FR7_3895	7.317e-21	109.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,4H3ZV@909932|Negativicutes	909932|Negativicutes	M	Transglycosylase SLT domain protein	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
GDHHQS3_k127_8355973_3	349161.Dred_2491	9.976e-36	147.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,262CU@186807|Peptococcaceae	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS3_k127_8355973_0	671143.DAMO_2247	2.048e-59	211.0	COG0766@1|root,COG0766@2|Bacteria,2NNUV@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS3_k127_8453178_0	502025.Hoch_0120	4.559e-36	157.0	COG5107@1|root,COG5107@2|Bacteria	2|Bacteria	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
GDHHQS3_k127_8482093_1	883126.HMPREF9710_00664	1.713e-67	254.0	COG0438@1|root,COG0438@2|Bacteria,1N0VQ@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
GDHHQS3_k127_8482093_4	927677.ALVU02000001_gene3544	2.333e-58	229.0	COG0463@1|root,COG0463@2|Bacteria,1G0KR@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Core-2 I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
GDHHQS3_k127_8482093_5	1144275.COCOR_01809	7.561e-52	199.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
GDHHQS3_k127_8482093_9	1297742.A176_05036	1.169e-19	105.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
GDHHQS3_k127_8482093_2	1122604.JONR01000033_gene34	7.345e-67	252.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
GDHHQS3_k127_8482093_10	1198114.AciX9_0816	1.359e-16	95.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8482093_0	983917.RGE_05150	1.306e-77	283.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,1KJUD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_8482093_7	1267534.KB906754_gene3175	2.779e-27	129.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8482093_8	1267535.KB906767_gene2751	7.777e-25	123.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8482093_6	743721.Psesu_1563	1.333e-38	161.0	COG0457@1|root,COG0457@2|Bacteria,1N2TR@1224|Proteobacteria,1T31T@1236|Gammaproteobacteria,1XCUK@135614|Xanthomonadales	135614|Xanthomonadales	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,Transglut_core
GDHHQS3_k127_8482093_3	1047013.AQSP01000123_gene1523	3.428e-61	222.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8482147_2	1047013.AQSP01000123_gene1523	1.654e-60	221.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8482147_1	1122604.JONR01000033_gene34	3.152e-61	237.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
GDHHQS3_k127_8482147_3	382464.ABSI01000011_gene2813	3.551e-56	211.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
GDHHQS3_k127_8482147_0	1267535.KB906767_gene2246	3.395e-104	356.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria,2JIWQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_8482147_4	1348114.OM33_20420	3.208e-21	100.0	COG1695@1|root,COG1695@2|Bacteria,1N4DF@1224|Proteobacteria,1SBH1@1236|Gammaproteobacteria,2Q31Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_8535382_2	314345.SPV1_07451	1.903e-29	135.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn,Glycos_transf_1
GDHHQS3_k127_8535382_1	1496688.ER33_03630	2.927e-56	214.0	COG1215@1|root,COG1215@2|Bacteria,1GMNJ@1117|Cyanobacteria,22TKP@167375|Cyanobium	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8535382_3	1123377.AUIV01000016_gene318	5.213e-22	112.0	COG1216@1|root,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,1X3ND@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
GDHHQS3_k127_8535382_0	414684.RC1_4027	1.774e-135	451.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JW1S@204441|Rhodospirillales	204441|Rhodospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_8539690_3	1537715.JQFJ01000001_gene2707	3.86e-33	130.0	2BWTW@1|root,315N7@2|Bacteria,1RABY@1224|Proteobacteria,2U5VH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8539690_5	191610.CATYP_06450	1.139e-18	100.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,22K3D@1653|Corynebacteriaceae	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS3_k127_8539690_4	1487953.JMKF01000028_gene1333	1.299e-25	124.0	COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,1HA4G@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GDHHQS3_k127_8539690_6	388739.RSK20926_21959	0.0001053	53.0	COG3128@1|root,COG3128@2|Bacteria,1NZ60@1224|Proteobacteria,2TV1H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8539690_2	1356852.N008_05720	1.826e-35	152.0	COG1629@1|root,COG2312@1|root,COG1629@2|Bacteria,COG2312@2|Bacteria,4NW00@976|Bacteroidetes,47SG3@768503|Cytophagia	976|Bacteroidetes	P	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarbopepD_reg_2,Erythro_esteras
GDHHQS3_k127_8539690_0	493475.GARC_1422	1.466e-230	750.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GDHHQS3_k127_8539690_1	234267.Acid_5749	3.577e-93	314.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GDHHQS3_k127_8542970_0	518766.Rmar_0899	7.916e-109	377.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS3_k127_8542970_1	765912.Thimo_0533	3.204e-54	201.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_8542970_3	580332.Slit_2647	3.003e-25	116.0	COG1262@1|root,COG1262@2|Bacteria,1RAMU@1224|Proteobacteria,2VX2U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,NACHT,TIR_2
GDHHQS3_k127_8542970_2	1123401.JHYQ01000012_gene2956	3.189e-48	182.0	COG0834@1|root,COG0834@2|Bacteria,1P18B@1224|Proteobacteria,1T0T9@1236|Gammaproteobacteria,463D0@72273|Thiotrichales	72273|Thiotrichales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SBP_bac_3
GDHHQS3_k127_8567695_10	420662.Mpe_A0463	3.609e-61	227.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1KJRM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_8567695_11	1452718.JBOY01000066_gene2398	8.633e-56	209.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
GDHHQS3_k127_8567695_7	204669.Acid345_3630	1.626e-91	313.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_8567695_8	1121468.AUBR01000006_gene362	4.391e-87	327.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_8567695_4	414684.RC1_0616	2.409e-128	419.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales	204441|Rhodospirillales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS3_k127_8567695_5	264732.Moth_0838	7.534e-103	374.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_8567695_3	443144.GM21_0502	2.565e-129	441.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
GDHHQS3_k127_8567695_17	240015.ACP_1093	1.377e-08	61.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
GDHHQS3_k127_8567695_9	391165.GbCGDNIH1_0437	1.747e-73	258.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2JPTV@204441|Rhodospirillales	204441|Rhodospirillales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS3_k127_8567695_12	903818.KI912269_gene110	4.38e-37	144.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS3_k127_8567695_19	1217718.ALOU01000019_gene2829	0.0003534	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1K2ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS3_k127_8567695_18	266264.Rmet_1882	0.0003125	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1K2ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS3_k127_8567695_1	234267.Acid_7421	2.427e-219	723.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria	57723|Acidobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS3_k127_8567695_13	1121406.JAEX01000007_gene2380	8.758e-29	118.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,42WKN@68525|delta/epsilon subdivisions,2WRXH@28221|Deltaproteobacteria,2MCPQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
GDHHQS3_k127_8567695_2	314230.DSM3645_07186	6.065e-141	470.0	COG1282@1|root,COG1282@2|Bacteria,2IYIA@203682|Planctomycetes	203682|Planctomycetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
GDHHQS3_k127_8567695_15	861299.J421_0967	3.87e-17	84.0	2C12A@1|root,33B7C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8567695_14	861299.J421_0966	1.547e-22	108.0	2E40T@1|root,32YXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8567695_16	1242864.D187_006920	7.851e-10	72.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8567695_6	861299.J421_1754	3.911e-92	317.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1ZTIR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
GDHHQS3_k127_8567695_0	234267.Acid_1492	1.578e-231	737.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_8599040_0	99598.Cal7507_5897	3.039e-95	329.0	COG1216@1|root,COG1216@2|Bacteria,1G346@1117|Cyanobacteria,1HIR4@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8599040_1	1173021.ALWA01000020_gene164	1.107e-89	308.0	COG0438@1|root,COG0438@2|Bacteria,1G23P@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_8671819_5	391625.PPSIR1_19419	6.275e-07	54.0	COG0659@1|root,COG0659@2|Bacteria,1MXA7@1224|Proteobacteria,42ZHY@68525|delta/epsilon subdivisions,2WV08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
GDHHQS3_k127_8671819_2	450851.PHZ_c0831	2.543e-52	195.0	COG4977@1|root,COG4977@2|Bacteria,1PFG6@1224|Proteobacteria,2V7GC@28211|Alphaproteobacteria,2KJ6G@204458|Caulobacterales	204458|Caulobacterales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
GDHHQS3_k127_8671819_4	682795.AciX8_3374	1.987e-23	111.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_8671819_1	240016.ABIZ01000001_gene3959	2.375e-66	252.0	COG0823@1|root,COG3712@1|root,COG0823@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	DUF389,FecR,Laminin_G_3
GDHHQS3_k127_8671819_0	661478.OP10G_1775	8.906e-165	531.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
GDHHQS3_k127_8671819_3	661478.OP10G_1774	5.933e-38	158.0	2C7PP@1|root,33K9Q@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
GDHHQS3_k127_8709872_11	105559.Nwat_1044	2.214e-56	214.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria	1224|Proteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8709872_29	318167.Sfri_3995	4.764e-05	52.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,2QBSH@267890|Shewanellaceae	1236|Gammaproteobacteria	S	BON domain	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GDHHQS3_k127_8709872_18	118166.JH976538_gene5065	1.311e-46	184.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_8709872_12	1128421.JAGA01000002_gene1765	2.267e-56	204.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
GDHHQS3_k127_8709872_6	84531.JMTZ01000070_gene1816	4.314e-111	375.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS3_k127_8709872_20	439235.Dalk_2975	3.886e-33	143.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_8709872_27	388051.AUFE01000016_gene5846	4.438e-12	71.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,1K9H1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS3_k127_8709872_1	1095769.CAHF01000008_gene3607	1.879e-144	480.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,473IQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Sigma-54 interaction domain	zraR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_8709872_32	42565.FP66_04335	0.0001334	54.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1XK22@135619|Oceanospirillales	135619|Oceanospirillales	M	Outer membrane protein W	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
GDHHQS3_k127_8709872_24	1161401.ASJA01000027_gene48	7.743e-21	94.0	COG3360@1|root,COG3360@2|Bacteria,1PURU@1224|Proteobacteria,2V0YI@28211|Alphaproteobacteria,43YVT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
GDHHQS3_k127_8709872_22	344747.PM8797T_27507	4.88e-25	106.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_8709872_17	1479237.JMLY01000001_gene3268	4.439e-47	188.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,4660F@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
GDHHQS3_k127_8709872_7	997346.HMPREF9374_3750	6.32e-101	343.0	COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,27AVZ@186824|Thermoactinomycetaceae	91061|Bacilli	S	N-terminal domain of oxidoreductase	yfmJ	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
GDHHQS3_k127_8709872_33	1123255.JHYS01000008_gene3086	0.0001686	48.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8709872_15	926549.KI421517_gene2433	1.026e-48	182.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,47YIZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GDHHQS3_k127_8709872_21	246197.MXAN_1552	1.449e-31	131.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_8709872_0	314278.NB231_07712	0.0	1316.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X2PZ@135613|Chromatiales	135613|Chromatiales	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
GDHHQS3_k127_8709872_25	452637.Oter_4069	1.148e-13	83.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,46US9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8709872_23	443144.GM21_2153	3.97e-21	104.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
GDHHQS3_k127_8709872_4	1504672.669782768	1.175e-119	398.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
GDHHQS3_k127_8709872_8	483219.LILAB_18865	2.849e-74	261.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,42ZZV@68525|delta/epsilon subdivisions,2WVCM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS3_k127_8709872_16	251221.35212001	1.151e-47	177.0	COG3832@1|root,COG3832@2|Bacteria,1G9XT@1117|Cyanobacteria	1117|Cyanobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_8709872_19	1254432.SCE1572_31280	1.371e-39	151.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,430Y1@68525|delta/epsilon subdivisions,2WVU4@28221|Deltaproteobacteria,2YVFD@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS3_k127_8709872_30	1384484.AEQU_0658	0.0001003	55.0	COG3119@1|root,COG3119@2|Bacteria,2HUM0@201174|Actinobacteria,4CV35@84998|Coriobacteriia	84998|Coriobacteriia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GDHHQS3_k127_8709872_28	935840.JAEQ01000001_gene3074	2.435e-05	51.0	2AGY4@1|root,33HSC@2|Bacteria,1NJ83@1224|Proteobacteria,2UWQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8709872_2	886293.Sinac_7570	1.339e-140	460.0	COG2242@1|root,COG2242@2|Bacteria,2J25Y@203682|Planctomycetes	203682|Planctomycetes	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8709872_5	247490.KSU1_D0083	1.245e-119	395.0	COG0451@1|root,COG0451@2|Bacteria,2IYBF@203682|Planctomycetes	203682|Planctomycetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GDHHQS3_k127_8709872_10	671143.DAMO_0905	1.167e-64	238.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8709872_31	309801.trd_1295	0.0001257	55.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XGX@189775|Thermomicrobia	189775|Thermomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_8709872_14	696747.NIES39_E02470	1.373e-49	203.0	COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1H9QQ@1150|Oscillatoriales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_8709872_9	1280944.HY17_19030	2.538e-69	252.0	COG1215@1|root,COG2604@1|root,COG1215@2|Bacteria,COG2604@2|Bacteria,1QVTJ@1224|Proteobacteria,2TXTU@28211|Alphaproteobacteria,43ZTK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_1,Glycos_transf_2
GDHHQS3_k127_8709872_3	56780.SYN_00827	1.167e-126	420.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2MQTT@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_8709872_13	56780.SYN_00826	3.669e-50	203.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,NodS
GDHHQS3_k127_8863326_4	404589.Anae109_2761	1.602e-73	273.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GDHHQS3_k127_8863326_3	648996.Theam_1254	1.376e-78	287.0	COG0057@1|root,COG0057@2|Bacteria,2G3TK@200783|Aquificae	200783|Aquificae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_8863326_2	1499967.BAYZ01000157_gene583	1.047e-119	410.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_8863326_0	246197.MXAN_5868	3.42e-227	716.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	fabB	-	2.3.1.179,2.3.1.180	ko:K09458,ko:K18473	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00082,M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R10707	RC00004,RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_8863326_6	1125863.JAFN01000001_gene1525	2.651e-41	176.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GDHHQS3_k127_8863326_8	1120988.AXWV01000041_gene830	4.792e-16	92.0	28N6Q@1|root,2ZBBI@2|Bacteria,1R719@1224|Proteobacteria,1S309@1236|Gammaproteobacteria,1Y56F@135624|Aeromonadales	135624|Aeromonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8863326_5	582515.KR51_00032180	2.993e-67	250.0	COG0116@1|root,COG0116@2|Bacteria,1G03K@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the methyltransferase superfamily	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
GDHHQS3_k127_8863326_7	519442.Huta_2179	2.366e-30	128.0	COG1853@1|root,arCOG02017@2157|Archaea	2157|Archaea	L	PFAM flavin reductase domain protein, FMN-binding	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016722,GO:0016723,GO:0032553,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.16.1.10	ko:K18915	-	-	-	-	ko00000,ko01000	-	-	-	Flavin_Reduct
GDHHQS3_k127_8863326_9	381666.H16_B2196	2.183e-13	85.0	COG1388@1|root,COG4254@1|root,COG1388@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,1K26R@119060|Burkholderiaceae	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GDHHQS3_k127_8863326_1	580332.Slit_1414	2.5e-154	497.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,44VKE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GDHHQS3_k127_894874_6	644282.Deba_2698	1.306e-82	289.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS3_k127_894874_23	1123321.KB905827_gene499	2.276e-09	70.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GDHHQS3_k127_894874_14	102129.Lepto7375DRAFT_6713	2.964e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,1G6A9@1117|Cyanobacteria,1HBB4@1150|Oscillatoriales	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_894874_17	1121430.JMLG01000005_gene683	2.325e-35	140.0	COG1611@1|root,COG1611@2|Bacteria,1V2D7@1239|Firmicutes,24KYJ@186801|Clostridia,262X1@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM TIGR00725 family protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_894874_16	391625.PPSIR1_04398	2.463e-36	141.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
GDHHQS3_k127_894874_22	1182590.BN5_03002	1.662e-11	76.0	COG0695@1|root,COG0695@2|Bacteria,1N6ZT@1224|Proteobacteria,1SD1U@1236|Gammaproteobacteria,1YJPT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	Glutaredoxin	nrdH	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GDHHQS3_k127_894874_9	309807.SRU_2559	1.462e-56	203.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1FJ8E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GDHHQS3_k127_894874_20	1123368.AUIS01000013_gene832	7.509e-25	108.0	COG4911@1|root,COG4911@2|Bacteria,1NPJ8@1224|Proteobacteria,1T8JU@1236|Gammaproteobacteria,2ND17@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GDHHQS3_k127_894874_19	290397.Adeh_3478	2.747e-33	144.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,431E6@68525|delta/epsilon subdivisions,2WWGA@28221|Deltaproteobacteria,2YVXB@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GDHHQS3_k127_894874_7	1038867.AXAY01000023_gene4617	1.626e-62	222.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2U13E@28211|Alphaproteobacteria,3JXB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major intrinsic protein	-	-	-	-	-	-	-	-	-	-	-	-	MIP
GDHHQS3_k127_894874_3	1210884.HG799462_gene8307	7.086e-156	500.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GDHHQS3_k127_894874_18	886293.Sinac_5084	1.44e-34	145.0	COG0354@1|root,COG0354@2|Bacteria,2IZWI@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_894874_11	1173028.ANKO01000116_gene5724	1.162e-44	173.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria,1HCZI@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_894874_10	240015.ACP_1661	1.238e-49	191.0	COG1024@1|root,COG1024@2|Bacteria,3Y3SE@57723|Acidobacteria,2JIII@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_894874_15	880073.Calab_1746	5.125e-37	144.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_894874_2	1121920.AUAU01000006_gene324	2.756e-189	601.0	COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria	57723|Acidobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
GDHHQS3_k127_894874_0	1238182.C882_2537	9.13e-301	932.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2TUPJ@28211|Alphaproteobacteria,2JRME@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
GDHHQS3_k127_894874_8	349521.HCH_06590	5.842e-57	216.0	COG1716@1|root,COG2200@1|root,COG1716@2|Bacteria,COG2200@2|Bacteria,1R86G@1224|Proteobacteria,1RQQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA
GDHHQS3_k127_894874_1	518766.Rmar_1663	7.728e-196	627.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1FIQN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Carboxyl transferase domain	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS3_k127_894874_4	1041930.Mtc_0200	3.567e-107	373.0	COG0367@1|root,COG0449@1|root,arCOG00057@2157|Archaea,arCOG00071@2157|Archaea,2XV5E@28890|Euryarchaeota,2N9BC@224756|Methanomicrobia	224756|Methanomicrobia	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB-1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_894874_12	1382356.JQMP01000004_gene472	5.782e-39	163.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,27XZI@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_894874_5	1380390.JIAT01000009_gene364	1.203e-104	363.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_894874_13	383372.Rcas_1898	1.23e-38	168.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi,3754Y@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_894874_24	1366050.N234_13160	1.02e-08	68.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1K984@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_894874_21	530564.Psta_2344	7.951e-25	113.0	COG0314@1|root,COG0314@2|Bacteria,2IZSA@203682|Planctomycetes	203682|Planctomycetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
GDHHQS3_k127_919894_1	481448.Minf_1944	7.823e-62	227.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,37G6Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GDHHQS3_k127_919894_3	1174528.JH992898_gene3801	1.045e-21	107.0	2FFFF@1|root,347CY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_919894_4	1288298.rosmuc_00823	2.674e-12	72.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1R6IF@1224|Proteobacteria,2TVGT@28211|Alphaproteobacteria,46PWI@74030|Roseovarius	28211|Alphaproteobacteria	QU	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
GDHHQS3_k127_919894_0	247490.KSU1_C1314	9.707e-101	348.0	COG0535@1|root,COG0535@2|Bacteria,2J2KS@203682|Planctomycetes	203682|Planctomycetes	S	Proto-chlorophyllide reductase 57 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	PCP_red,Radical_SAM,SPASM
GDHHQS3_k127_919894_2	1131269.AQVV01000011_gene2523	1.22e-39	160.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
GDHHQS3_k127_919894_6	1122247.C731_0609	8.937e-05	54.0	COG0454@1|root,COG0456@2|Bacteria,2H5WU@201174|Actinobacteria,235BK@1762|Mycobacteriaceae	201174|Actinobacteria	K	acetyltransferase	-	-	2.3.1.1	ko:K22476	ko00220,ko01210,ko01230,map00220,map01210,map01230	-	R00259	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
## 2956 queries scanned
## Total time (seconds): 85.1609787940979
## Rate: 34.71 q/s