## Wed Oct 16 00:49:07 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/GDHHQS3_bin.7.fa -m mmseqs --itype genome -o GDHHQS3_bin.7 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/GDHHQS3_bin.7 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs GDHHQS3_k127_105935_2 1122194.AUHU01000002_gene2492 7.514e-20 92.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b GDHHQS3_k127_105935_1 1384054.N790_01245 8.846e-43 167.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1X5BW@135614|Xanthomonadales 135614|Xanthomonadales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA GDHHQS3_k127_105935_0 1234364.AMSF01000016_gene1557 6.249e-218 683.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1X4F7@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein ftsk ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - Cupin_4,FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma GDHHQS3_k127_1082203_2 309799.DICTH_1519 3.112e-57 211.0 COG0119@1|root,COG0119@2|Bacteria 2|Bacteria E Belongs to the alpha-IPM synthase homocitrate synthase family nifV - 2.3.3.14 ko:K02594 ko00620,map00620 - R00271 RC00004,RC00067,RC02754 ko00000,ko00001,ko01000 - - - HMGL-like GDHHQS3_k127_1082203_7 1121949.AQXT01000002_gene1508 2.756e-25 115.0 2EPG8@1|root,33H2V@2|Bacteria,1Q81Y@1224|Proteobacteria,2V792@28211|Alphaproteobacteria,44045@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1082203_8 1158762.KB898038_gene2052 1.823e-17 88.0 COG4113@1|root,COG4113@2|Bacteria,1PSN3@1224|Proteobacteria,1STZ6@1236|Gammaproteobacteria,1X1RN@135613|Chromatiales 135613|Chromatiales S PIN domain - - - - - - - - - - - - PIN GDHHQS3_k127_1082203_9 1452535.JARD01000028_gene2341 1.654e-13 76.0 COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria,4FSMX@85023|Microbacteriaceae 201174|Actinobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - GDHHQS3_k127_1082203_5 1049564.TevJSym_aa00830 2.34e-40 155.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 GDHHQS3_k127_1082203_6 1198452.Jab_2c23300 6.443e-33 134.0 2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1082203_4 404589.Anae109_2821 3.731e-41 154.0 COG3791@1|root,COG3791@2|Bacteria,1N7AZ@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA GDHHQS3_k127_1082203_10 228405.HNE_3278 2.831e-06 53.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,43XWS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 GDHHQS3_k127_1082203_0 296591.Bpro_1663 2.02e-60 213.0 COG1917@1|root,COG1917@2|Bacteria,1MZFB@1224|Proteobacteria 1224|Proteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 GDHHQS3_k127_1082203_1 443218.AS9A_2587 1.874e-58 214.0 COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria 201174|Actinobacteria S Thioesterase - - - - - - - - - - - - - GDHHQS3_k127_1082203_3 1123073.KB899241_gene2956 3.576e-44 163.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1X6GE@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N GDHHQS3_k127_110278_6 1384054.N790_10985 2.017e-07 53.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1X68Z@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf GDHHQS3_k127_110278_2 1384056.N787_03745 4.9e-132 442.0 COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales 135614|Xanthomonadales S Dak2 - - - ko:K07030 - - - - ko00000 - - - Dak2,DegV GDHHQS3_k127_110278_4 323261.Noc_0216 2.317e-11 67.0 COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria 1224|Proteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins XAC3035 - - - - - - - - - - - DUF836 GDHHQS3_k127_110278_1 1163408.UU9_15015 1.133e-214 674.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales 135614|Xanthomonadales E Serine dehydratase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta GDHHQS3_k127_110278_3 697282.Mettu_2654 5.587e-68 242.0 COG0739@1|root,COG0739@2|Bacteria,1RIS0@1224|Proteobacteria,1S6KP@1236|Gammaproteobacteria,1XG3T@135618|Methylococcales 135618|Methylococcales M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 GDHHQS3_k127_110278_0 519989.ECTPHS_00590 1.764e-248 776.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales 135613|Chromatiales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C GDHHQS3_k127_110278_5 1385515.N791_06100 3.245e-10 65.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1X3AE@135614|Xanthomonadales 135614|Xanthomonadales F Na dependent nucleoside transporter yeiM - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N GDHHQS3_k127_1140515_18 857087.Metme_4335 1.024e-16 80.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1XFBH@135618|Methylococcales 135618|Methylococcales O Belongs to the thioredoxin family - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin GDHHQS3_k127_1140515_3 187272.Mlg_0367 1.098e-219 687.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales 135613|Chromatiales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind GDHHQS3_k127_1140515_2 187272.Mlg_2601 8.421e-220 691.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1WWIP@135613|Chromatiales 135613|Chromatiales S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD GDHHQS3_k127_1140515_15 305700.B447_00750 3.969e-39 152.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,2KWAK@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome B561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB GDHHQS3_k127_1140515_17 1300345.LF41_1997 1.443e-24 110.0 COG2353@1|root,COG2353@2|Bacteria,1R5CT@1224|Proteobacteria,1SG12@1236|Gammaproteobacteria,1X6BJ@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI GDHHQS3_k127_1140515_16 204773.HEAR2692 3.005e-29 128.0 COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,2VSMB@28216|Betaproteobacteria,4779W@75682|Oxalobacteraceae 28216|Betaproteobacteria S YceI-like domain - - - - - - - - - - - - YceI GDHHQS3_k127_1140515_6 553385.JEMF01000050_gene2125 3.175e-163 520.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1XI36@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt GDHHQS3_k127_1140515_10 523791.Kkor_0998 7.176e-131 424.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1XI1U@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase GDHHQS3_k127_1140515_7 1234364.AMSF01000032_gene3386 7.998e-154 491.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1X3NI@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N GDHHQS3_k127_1140515_11 1234364.AMSF01000070_gene2161 8.138e-81 282.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1X4WZ@135614|Xanthomonadales 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C GDHHQS3_k127_1140515_1 187272.Mlg_0941 1.908e-281 876.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales 135613|Chromatiales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 GDHHQS3_k127_1140515_4 1121015.N789_06160 6.352e-211 663.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales 135614|Xanthomonadales E phospho-2-dehydro-3-deoxyheptonate aldolase dhs1 - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 GDHHQS3_k127_1140515_13 748280.NH8B_2621 4.316e-49 183.0 COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,2KTVE@206351|Neisseriales 206351|Neisseriales C Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB GDHHQS3_k127_1140515_0 518766.Rmar_1593 2.177e-287 891.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N GDHHQS3_k127_1140515_5 1210884.HG799463_gene10136 7.859e-211 666.0 COG2986@1|root,COG2986@2|Bacteria,2IZUM@203682|Planctomycetes 203682|Planctomycetes E Aromatic amino acid lyase - - 4.3.1.24 ko:K10775 ko00360,ko00940,ko01100,ko01110,map00360,map00940,map01100,map01110 M00039,M00137,M00350 R00697 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic GDHHQS3_k127_1140515_9 518766.Rmar_1595 2.502e-144 469.0 COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes 976|Bacteroidetes Q Belongs to the metallo-dependent hydrolases superfamily. HutI family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 GDHHQS3_k127_1140515_19 445335.CBN_1157 1.164e-06 53.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,36MTC@31979|Clostridiaceae 186801|Clostridia P ferrous iron transport protein feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA GDHHQS3_k127_1140515_8 518766.Rmar_2567 1.611e-153 511.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate GDHHQS3_k127_1140515_12 1123253.AUBD01000007_gene734 2.03e-56 199.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1X6D2@135614|Xanthomonadales 135614|Xanthomonadales J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 GDHHQS3_k127_1140515_14 1453501.JELR01000005_gene1745 2.218e-47 171.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,464HA@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L GDHHQS3_k127_114759_1 768706.Desor_1122 2.235e-90 308.0 COG0591@1|root,COG0591@2|Bacteria,1TQEZ@1239|Firmicutes,24AJN@186801|Clostridia,262IJ@186807|Peptococcaceae 186801|Clostridia E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF GDHHQS3_k127_114759_0 1123240.ATVO01000004_gene939 9.337e-95 319.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH GDHHQS3_k127_1149091_2 933262.AXAM01000009_gene1436 2.653e-61 222.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase GDHHQS3_k127_1149091_1 324925.Ppha_0527 1.211e-131 427.0 COG2089@1|root,COG2089@2|Bacteria,1FD73@1090|Chlorobi 1090|Chlorobi H PFAM N-acetylneuraminic acid synthase - - 2.5.1.101 ko:K18430 ko00520,map00520 - R10304 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF GDHHQS3_k127_1149091_0 324925.Ppha_0528 1.182e-183 581.0 COG0381@1|root,COG0381@2|Bacteria 2|Bacteria M UDP-N-acetylglucosamine 2-epimerase activity neuC GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576 3.2.1.184,5.1.3.14 ko:K01791,ko:K18429 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R10187 RC00005,RC00288,RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 GDHHQS3_k127_1149091_3 870187.Thini_1620 5.617e-36 141.0 COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RQPI@1236|Gammaproteobacteria,461QS@72273|Thiotrichales 72273|Thiotrichales JM Nucleotidyl transferase - - - - - - - - - - - - CBS,NTP_transferase GDHHQS3_k127_1149705_1 1313301.AUGC01000003_gene2093 4.036e-77 271.0 COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes 976|Bacteroidetes C radical SAM domain protein - - - - - - - - - - - - SPASM GDHHQS3_k127_1149705_2 1210884.HG799471_gene14594 1.279e-50 195.0 COG0438@1|root,COG0438@2|Bacteria,2J077@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_1149705_4 671143.DAMO_0904 5.427e-05 55.0 COG1493@1|root,COG1493@2|Bacteria,2NRXF@2323|unclassified Bacteria 2|Bacteria T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - - - - - - - - - - DRTGG GDHHQS3_k127_1149705_0 269798.CHU_2121 1.571e-122 402.0 COG2890@1|root,COG2890@2|Bacteria,4PM1Z@976|Bacteroidetes,47NBU@768503|Cytophagia 976|Bacteroidetes J O-methyltransferase - - - - - - - - - - - - Methyltransf_2 GDHHQS3_k127_1149705_3 398579.Spea_0382 2.031e-19 91.0 2E8FX@1|root,33HMC@2|Bacteria,1NMZA@1224|Proteobacteria,1T0KI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1153401_4 1384056.N787_08905 1.5e-27 115.0 COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1X5H8@135614|Xanthomonadales 135614|Xanthomonadales GM ABC transporter - - - - - - - - - - - - ABC_tran GDHHQS3_k127_1153401_0 1384056.N787_08910 5.277e-76 268.0 COG1216@1|root,COG1216@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria,1X4AI@135614|Xanthomonadales 135614|Xanthomonadales S glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_1153401_1 1123073.KB899241_gene3172 2.024e-66 238.0 COG2227@1|root,COG2227@2|Bacteria,1N6SE@1224|Proteobacteria,1SCC1@1236|Gammaproteobacteria,1X6AF@135614|Xanthomonadales 135614|Xanthomonadales H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_1153401_2 344747.PM8797T_20274 3.206e-51 192.0 COG1216@1|root,COG1216@2|Bacteria,2J0AR@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 GDHHQS3_k127_1153401_3 1382303.JPOM01000001_gene1534 1.57e-38 158.0 COG0451@1|root,COG0451@2|Bacteria,1RB7F@1224|Proteobacteria,2TWFG@28211|Alphaproteobacteria,2KJUM@204458|Caulobacterales 204458|Caulobacterales GM NAD dependent epimerase/dehydratase family - - - - - - - - - - - - Epimerase GDHHQS3_k127_1171249_2 935840.JAEQ01000019_gene2068 8.482e-99 334.0 COG0665@1|root,COG0665@2|Bacteria,1PGZV@1224|Proteobacteria,2V8BN@28211|Alphaproteobacteria,43PY8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO GDHHQS3_k127_1171249_6 565045.NOR51B_1369 2.337e-52 188.0 COG0251@1|root,COG0251@2|Bacteria,1RH5K@1224|Proteobacteria,1SE2G@1236|Gammaproteobacteria 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP GDHHQS3_k127_1171249_5 565045.NOR51B_431 3.513e-63 220.0 COG0346@1|root,COG0346@2|Bacteria,1R8DA@1224|Proteobacteria,1S68W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - 5.1.3.33 ko:K20431 ko00525,ko01130,map00525,map01130 M00815 R11079 RC01519 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase,Glyoxalase_4 GDHHQS3_k127_1171249_0 314285.KT71_06324 1.763e-137 451.0 COG1914@1|root,COG1914@2|Bacteria,1NU59@1224|Proteobacteria,1SMRT@1236|Gammaproteobacteria,1J9QT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp GDHHQS3_k127_1171249_4 316274.Haur_0331 4.648e-80 276.0 COG1506@1|root,COG1506@2|Bacteria,2GA6W@200795|Chloroflexi 200795|Chloroflexi E alpha/beta hydrolase fold - - - - - - - - - - - - Peptidase_S9 GDHHQS3_k127_1171249_7 1121374.KB891589_gene47 4.731e-48 180.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S4A4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR,TetR_N GDHHQS3_k127_1171249_3 1121374.KB891589_gene48 3.969e-92 317.0 COG0662@1|root,COG0662@2|Bacteria,1QZVZ@1224|Proteobacteria,1T4RF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Iron-binding zinc finger CDGSH type - - - - - - - - - - - - Cupin_2 GDHHQS3_k127_1171249_1 565045.NOR51B_2554 4.055e-136 447.0 COG0733@1|root,COG0733@2|Bacteria,1NQUA@1224|Proteobacteria,1SN07@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - - - - - - - - - - SNF GDHHQS3_k127_1171249_8 316274.Haur_3782 3.569e-05 48.0 COG0520@1|root,COG0520@2|Bacteria,2G7N0@200795|Chloroflexi,377HP@32061|Chloroflexia 32061|Chloroflexia H PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 GDHHQS3_k127_1171607_0 765911.Thivi_2556 0.0 1630.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales 135613|Chromatiales G Glycosyltransferase 36 associated - - - - - - - - - - - - Glyco_hydro_36,Glyco_transf_36,Glycoamylase GDHHQS3_k127_1175670_1 946483.Cenrod_1878 2.086e-26 109.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,4ADW1@80864|Comamonadaceae 28216|Betaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL GDHHQS3_k127_1175670_0 666685.R2APBS1_3503 3.066e-186 602.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1X381@135614|Xanthomonadales 135614|Xanthomonadales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII GDHHQS3_k127_1180542_3 1380358.JADJ01000007_gene2924 3.75e-08 64.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1XMY1@135619|Oceanospirillales 135619|Oceanospirillales Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_1180542_0 402881.Plav_2625 3.65e-148 481.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,1JN2M@119043|Rhodobiaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase ordL - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO GDHHQS3_k127_1180542_1 314285.KT71_03492 4.078e-97 338.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1J804@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X GDHHQS3_k127_1180542_2 876044.IMCC3088_1594 3.881e-38 145.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1J4ZP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 GDHHQS3_k127_1219396_3 1178482.BJB45_00960 4.659e-29 119.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XJ29@135619|Oceanospirillales 135619|Oceanospirillales P transporter, permease oppB - - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 GDHHQS3_k127_1219396_0 1122135.KB893137_gene1273 1.279e-160 525.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type oligopeptide transport system periplasmic component - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GDHHQS3_k127_1219396_1 1415780.JPOG01000001_gene226 3.326e-127 430.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales 135614|Xanthomonadales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GDHHQS3_k127_1219396_2 1430440.MGMSRv2_4083 6.801e-77 261.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2JPAV@204441|Rhodospirillales 204441|Rhodospirillales H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 GDHHQS3_k127_1223398_2 1265313.HRUBRA_01348 1.796e-120 402.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - DUF222,HNH GDHHQS3_k127_1223398_1 1217708.F887_03467 1.356e-270 844.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,1RNHM@1236|Gammaproteobacteria,3NM2H@468|Moraxellaceae 1236|Gammaproteobacteria L COG2189 Adenine specific DNA methylase Mod mod - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase GDHHQS3_k127_1223398_4 1232410.KI421413_gene566 4.91e-59 213.0 COG2184@1|root,COG2184@2|Bacteria,1QREW@1224|Proteobacteria,43B8J@68525|delta/epsilon subdivisions 1224|Proteobacteria D Fic/DOC family fic - - ko:K04095 - - - - ko00000,ko03036 - - - Fic GDHHQS3_k127_1223398_0 153948.NAL212_1499 0.0 1402.0 COG1061@1|root,COG1061@2|Bacteria,1MX92@1224|Proteobacteria,2VM99@28216|Betaproteobacteria,372UN@32003|Nitrosomonadales 28216|Betaproteobacteria KL PFAM Restriction endonuclease, type I, R subunit Type III, Res subunit - - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII GDHHQS3_k127_1223398_6 1458427.BAWN01000028_gene1651 2.759e-20 95.0 COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,2VP78@28216|Betaproteobacteria,4AEVC@80864|Comamonadaceae 28216|Betaproteobacteria S Virulence protein RhuM family - - - - - - - - - - - - Fic,Virulence_RhuM GDHHQS3_k127_1223398_7 472759.Nhal_0280 7.489e-15 88.0 COG2335@1|root,COG2335@2|Bacteria 2|Bacteria M COG2335, Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - CHRD,Fasciclin GDHHQS3_k127_1223398_3 382464.ABSI01000012_gene2198 5.918e-95 339.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C GDHHQS3_k127_1223398_5 420662.Mpe_A0884 5.637e-24 104.0 COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,2VMK1@28216|Betaproteobacteria,1KM97@119065|unclassified Burkholderiales 28216|Betaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_1227163_0 1123073.KB899241_gene2898 2.661e-204 659.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1X4W6@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 GDHHQS3_k127_1227163_1 767434.Fraau_0584 5.694e-162 514.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1X4DA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM GDHHQS3_k127_1227163_2 1123073.KB899241_gene2900 8.02e-39 148.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1X4H1@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB GDHHQS3_k127_1231200_2 1121937.AUHJ01000001_gene613 3.386e-38 147.0 COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,1RZ77@1236|Gammaproteobacteria,467KY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0052 - - 2.7.8.28 ko:K11212 ko00680,ko01120,map00680,map01120 M00378 R09398 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - UPF0052 GDHHQS3_k127_1231200_0 13690.CP98_02510 1.695e-69 254.0 COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,2TU1P@28211|Alphaproteobacteria,2K28G@204457|Sphingomonadales 204457|Sphingomonadales S F420-0:Gamma-glutamyl ligase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase GDHHQS3_k127_1231200_1 745310.G432_18305 3.011e-53 206.0 COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,2TS1W@28211|Alphaproteobacteria,2K27G@204457|Sphingomonadales 204457|Sphingomonadales S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored GDHHQS3_k127_1231200_3 1163409.UUA_16408 5.3e-24 100.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase GDHHQS3_k127_1237989_3 1121923.GPUN_0358 1.002e-124 408.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,466PN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B GDHHQS3_k127_1237989_2 1121923.GPUN_0359 1.267e-138 446.0 COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,1RY5K@1236|Gammaproteobacteria,46BCS@72275|Alteromonadaceae 1236|Gammaproteobacteria G Transketolase, thiamine diphosphate binding domain IV02_09715 - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N GDHHQS3_k127_1237989_1 1121923.GPUN_0360 1.891e-159 507.0 COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,1RYXD@1236|Gammaproteobacteria,467Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria G Transketolase, pyrimidine binding domain IV02_09720 - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C GDHHQS3_k127_1237989_0 1121923.GPUN_0361 3.999e-160 514.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RPAZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PFAM Ribulose bisphosphate carboxylase large - - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large GDHHQS3_k127_1238955_2 658612.MD26_21105 4.983e-74 259.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,1RNR4@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily vanK - - - - - - - - - - - MFS_1,MFS_4 GDHHQS3_k127_1238955_0 518766.Rmar_1990 6.411e-121 398.0 COG4257@1|root,COG4257@2|Bacteria 2|Bacteria V antibiotic catabolic process - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - DUF5011 GDHHQS3_k127_1238955_1 1123073.KB899241_gene3395 2.939e-80 272.0 COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_1251655_1 414684.RC1_1357 9.183e-85 295.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2JQY4@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC GDHHQS3_k127_1251655_0 552811.Dehly_0239 3.672e-113 370.0 COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi 200795|Chloroflexi O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH GDHHQS3_k127_1253674_2 675817.VDA_003323 1.413e-17 88.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1XTST@135623|Vibrionales 135623|Vibrionales O protein required for cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA GDHHQS3_k127_1253674_1 589865.DaAHT2_0387 6.634e-29 124.0 COG2706@1|root,COG5276@1|root,COG5492@1|root,COG2706@2|Bacteria,COG5276@2|Bacteria,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,42U3Q@68525|delta/epsilon subdivisions,2WQZX@28221|Deltaproteobacteria,2MKPP@213118|Desulfobacterales 28221|Deltaproteobacteria N PFAM Ig domain protein group 2 domain protein - - - - - - - - - - - - Big_2,DUF1566,Peptidase_C13 GDHHQS3_k127_1253674_3 1123360.thalar_02883 2.679e-13 71.0 2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1253674_0 596154.Alide2_3909 2.442e-66 228.0 COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria,4AGHP@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM cytochrome c oxidase subunit II - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 GDHHQS3_k127_1254855_1 1500893.JQNB01000001_gene2006 3.508e-47 171.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1X49Q@135614|Xanthomonadales 135614|Xanthomonadales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA GDHHQS3_k127_1254855_2 1336245.JAGO01000010_gene914 9.625e-20 97.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XM17@135619|Oceanospirillales 135619|Oceanospirillales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX GDHHQS3_k127_1254855_0 511.JT27_15155 5.99e-188 593.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,3T1WD@506|Alcaligenaceae 28216|Betaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD GDHHQS3_k127_1256307_0 1120951.AUBG01000012_gene1544 4.662e-122 415.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,HTH_18,TPR_8 GDHHQS3_k127_1256307_2 1442599.JAAN01000033_gene1594 8.311e-68 236.0 COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,1X5DN@135614|Xanthomonadales 135614|Xanthomonadales EJ asparaginase VL23_12675 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase GDHHQS3_k127_1256307_1 1379270.AUXF01000003_gene3578 1.349e-87 304.0 COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Protein of unknown function (DUF445) - - - - - - - - - - - - DUF445 GDHHQS3_k127_1256307_4 399739.Pmen_1824 9.939e-39 149.0 COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,1YGAQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 GDHHQS3_k127_1256307_3 1121104.AQXH01000003_gene364 2.213e-49 184.0 COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IX9A@117747|Sphingobacteriia 976|Bacteroidetes O Redoxin - - - - - - - - - - - - AhpC-TSA GDHHQS3_k127_1260782_2 1384056.N787_10265 1.689e-78 281.0 COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,1S516@1236|Gammaproteobacteria,1XCBP@135614|Xanthomonadales 135614|Xanthomonadales S MTH538 TIR-like domain (DUF1863) - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF1863,WD40 GDHHQS3_k127_1260782_3 1411685.U062_01513 4.331e-28 119.0 COG0848@1|root,COG0848@2|Bacteria,1RHQ3@1224|Proteobacteria,1S7BK@1236|Gammaproteobacteria,1JBZW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD GDHHQS3_k127_1260782_0 1122603.ATVI01000011_gene2091 6.885e-233 735.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1X43R@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS GDHHQS3_k127_1260782_1 935863.AWZR01000001_gene1878 1.511e-155 503.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1X2YF@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 GDHHQS3_k127_1279422_3 234267.Acid_7851 1.575e-76 273.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria 57723|Acidobacteria K Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_1279422_5 1144307.PMI04_02042 2.879e-08 63.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,2U5RX@28211|Alphaproteobacteria,2K5KG@204457|Sphingomonadales 204457|Sphingomonadales S Yip1 domain - - - - - - - - - - - - Yip1 GDHHQS3_k127_1279422_1 1265503.KB905162_gene3650 5.905e-98 342.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,2Q73E@267889|Colwelliaceae 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 GDHHQS3_k127_1279422_0 1189612.A33Q_2393 2.017e-156 504.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47KDB@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - - - - - - - - - - - Peptidase_S58 GDHHQS3_k127_1279422_2 1280950.HJO_00770 9.389e-86 311.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_1279422_4 349163.Acry_2793 6.909e-38 142.0 COG3791@1|root,COG3791@2|Bacteria,1MX4A@1224|Proteobacteria,2TSAN@28211|Alphaproteobacteria,2JV7J@204441|Rhodospirillales 204441|Rhodospirillales S Glutathione-dependent formaldehyde-activating enzyme - - 4.4.1.22 ko:K03396 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R06982 RC00069,RC01707 ko00000,ko00001,ko01000 - - - GFA GDHHQS3_k127_1288463_0 1144275.COCOR_07888 2.089e-23 116.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - CHAT,TPR_12,TPR_7 GDHHQS3_k127_1288463_1 314285.KT71_02627 4.537e-14 72.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_1300574_0 768671.ThimaDRAFT_3378 5.659e-289 905.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V GDHHQS3_k127_1304714_1 1408444.JHYC01000011_gene992 7.538e-82 274.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1JDWB@118969|Legionellales 118969|Legionellales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome GDHHQS3_k127_1304714_0 396588.Tgr7_0057 4.038e-193 617.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales 135613|Chromatiales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small GDHHQS3_k127_1310054_0 1122185.N792_07230 3.975e-119 392.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,1X52V@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 GDHHQS3_k127_1310054_1 743721.Psesu_3035 4.258e-113 375.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X51T@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_1310054_3 572477.Alvin_1456 4.026e-56 215.0 COG1566@1|root,COG1566@2|Bacteria,1RBK7@1224|Proteobacteria,1S241@1236|Gammaproteobacteria,1X2HT@135613|Chromatiales 135613|Chromatiales V HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - HlyD_3 GDHHQS3_k127_1310054_4 1122194.AUHU01000005_gene878 1.329e-33 138.0 COG1309@1|root,COG1309@2|Bacteria,1PFEP@1224|Proteobacteria,1TAD5@1236|Gammaproteobacteria,468XZ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GDHHQS3_k127_1310054_2 1424334.W822_03610 9.129e-70 238.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2WF7W@28216|Betaproteobacteria,3T4A4@506|Alcaligenaceae 28216|Betaproteobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas GDHHQS3_k127_1313722_7 1417296.U879_08060 7.085e-17 84.0 COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,2UBE9@28211|Alphaproteobacteria 28211|Alphaproteobacteria F GMP synthase (glutamine-hydrolyzing) activity - - - - - - - - - - - - - GDHHQS3_k127_1313722_3 1417296.U879_08035 9.422e-113 374.0 COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2U1PC@28211|Alphaproteobacteria 28211|Alphaproteobacteria H biotin lipoate A B protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB GDHHQS3_k127_1313722_0 371731.Rsw2DRAFT_1853 1.315e-219 687.0 COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,2U4HP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM GDHHQS3_k127_1313722_1 1417296.U879_08050 1.415e-162 517.0 COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,2U1YU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Radical SAM - - - ko:K09711 - - - - ko00000 - - - Radical_SAM GDHHQS3_k127_1313722_2 1417296.U879_08055 2.815e-129 423.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria 28211|Alphaproteobacteria BQ Including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl GDHHQS3_k127_1313722_4 648757.Rvan_0605 2.91e-71 244.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2U6FZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 GDHHQS3_k127_1313722_5 1417296.U879_08115 1.254e-29 120.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria 1224|Proteobacteria O Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA GDHHQS3_k127_1313722_6 391937.NA2_06822 3.356e-19 87.0 COG2128@1|root,COG2128@2|Bacteria,1NDTM@1224|Proteobacteria,2U4SU@28211|Alphaproteobacteria,43MHY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD GDHHQS3_k127_131440_5 395495.Lcho_1551 8.185e-12 66.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,1KM3E@119065|unclassified Burkholderiales 28216|Betaproteobacteria P subunit of a heme lyase ccmH - - ko:K02200 - - - - ko00000 - - - CcmH GDHHQS3_k127_131440_3 1385515.N791_12470 4.442e-42 169.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1X3KB@135614|Xanthomonadales 135614|Xanthomonadales O Cytochrome C biogenesis cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_19,TPR_2 GDHHQS3_k127_131440_2 523791.Kkor_0590 3.973e-87 299.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XRBY@135619|Oceanospirillales 135619|Oceanospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_131440_0 1211114.ALIP01000042_gene476 1.708e-125 411.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X47D@135614|Xanthomonadales 135614|Xanthomonadales E Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 GDHHQS3_k127_131440_1 1300345.LF41_2649 5.012e-119 404.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - - GDHHQS3_k127_131440_4 13333.ERN03432 1.835e-33 136.0 28JIP@1|root,2QRXU@2759|Eukaryota,37IS9@33090|Viridiplantae,3GBCD@35493|Streptophyta 35493|Streptophyta S endonuclease - GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - - - - - - - - - - S1-P1_nuclease GDHHQS3_k127_1322608_4 1454004.AW11_00371 1.982e-42 158.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria 28216|Betaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_1322608_3 1458427.BAWN01000044_gene2076 1.049e-48 189.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,2VJVW@28216|Betaproteobacteria,4ACN0@80864|Comamonadaceae 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family nolF - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 GDHHQS3_k127_1322608_5 1348583.ATLH01000029_gene1592 9.449e-15 80.0 COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,1FADG@104264|Cellulophaga 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 GDHHQS3_k127_1322608_2 378806.STAUR_3770 1.789e-77 265.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,42ZS6@68525|delta/epsilon subdivisions,2WUZM@28221|Deltaproteobacteria,2YYRA@29|Myxococcales 28221|Deltaproteobacteria F Deoxynucleoside kinase - - - - - - - - - - - - dNK GDHHQS3_k127_1322608_1 383381.EH30_02410 7.248e-79 286.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2K2YU@204457|Sphingomonadales 204457|Sphingomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_8 GDHHQS3_k127_1322608_0 1121033.AUCF01000030_gene161 1.236e-265 826.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria,2JQI9@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF GDHHQS3_k127_1323218_1 498211.CJA_3146 1.024e-17 83.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1FFRR@10|Cellvibrio 1236|Gammaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3503,iYL1228.KPN_03625 Fer4_11,Fer4_20,Pyr_redox_2 GDHHQS3_k127_1323218_0 932213.SPM24T3_01190 0.0 1693.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,400KP@613|Serratia 1236|Gammaproteobacteria E Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase GDHHQS3_k127_1326139_9 1142394.PSMK_28130 1.728e-42 173.0 2DRTQ@1|root,32URN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1326139_11 290398.Csal_2929 2.245e-30 126.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales 135619|Oceanospirillales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar GDHHQS3_k127_1326139_0 545264.KB898744_gene2274 2.456e-205 660.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales 135613|Chromatiales E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 GDHHQS3_k127_1326139_2 1500893.JQNB01000001_gene950 3.748e-101 340.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1X303@135614|Xanthomonadales 135614|Xanthomonadales L exodeoxyribonuclease III xthA2 - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos GDHHQS3_k127_1326139_1 1123253.AUBD01000010_gene2153 2.253e-105 351.0 COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,1SKDF@1236|Gammaproteobacteria,1XCMH@135614|Xanthomonadales 135614|Xanthomonadales OP Rhodanese Homology Domain - - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin,Rhodanese GDHHQS3_k127_1326139_10 1163407.UU7_16972 2.453e-33 143.0 29KGK@1|root,307DX@2|Bacteria,1P3RW@1224|Proteobacteria,1RWAR@1236|Gammaproteobacteria,1X318@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_1326139_7 1173026.Glo7428_1817 2.709e-77 265.0 COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria 1117|Cyanobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE GDHHQS3_k127_1326139_8 1535422.ND16A_2142 2.903e-45 170.0 COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 GDHHQS3_k127_1326139_5 644966.Tmar_0689 2.121e-88 311.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia 186801|Clostridia P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GDHHQS3_k127_1326139_4 1121861.KB899937_gene4028 2.131e-90 310.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales 28211|Alphaproteobacteria EP Belongs to the ABC transporter superfamily - - - - - - - - - - - - ABC_tran,oligo_HPY GDHHQS3_k127_1326139_3 1415780.JPOG01000001_gene1822 3.371e-92 317.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1S670@1236|Gammaproteobacteria,1X9PH@135614|Xanthomonadales 135614|Xanthomonadales EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 GDHHQS3_k127_1326139_6 1415779.JOMH01000001_gene3135 8.585e-86 288.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1S4HN@1236|Gammaproteobacteria,1X9SZ@135614|Xanthomonadales 135614|Xanthomonadales EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 GDHHQS3_k127_1328620_2 935567.JAES01000004_gene119 7.213e-17 83.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1X4BP@135614|Xanthomonadales 135614|Xanthomonadales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran GDHHQS3_k127_1328620_0 1207063.P24_13668 9.47e-170 544.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2JPC2@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim GDHHQS3_k127_1328620_1 1123073.KB899242_gene1224 7.7e-165 544.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,1X5B6@135614|Xanthomonadales 135614|Xanthomonadales O PA domain - - - - - - - - - - - - He_PIG,PA,Peptidase_S8 GDHHQS3_k127_1335021_1 1123073.KB899241_gene2013 1.904e-100 350.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1X36E@135614|Xanthomonadales 135614|Xanthomonadales S von willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_16,TPR_2,VWA_2 GDHHQS3_k127_1335021_0 243233.MCA3085 2.649e-104 352.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA GDHHQS3_k127_1335021_4 631362.Thi970DRAFT_03276 2.194e-24 108.0 COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,1WYQH@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 GDHHQS3_k127_1335021_3 631362.Thi970DRAFT_03275 1.539e-68 244.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1WWS2@135613|Chromatiales 135613|Chromatiales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 GDHHQS3_k127_1335021_2 1234364.AMSF01000075_gene1927 9.32e-77 261.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1X580@135614|Xanthomonadales 135614|Xanthomonadales S ATPase (AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 GDHHQS3_k127_1339391_5 1333507.AUTQ01000140_gene2783 1.437e-41 159.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,2Q2IN@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 GDHHQS3_k127_1339391_7 118161.KB235922_gene3339 8.698e-28 122.0 COG0457@1|root,COG0500@1|root,COG0457@2|Bacteria,COG0500@2|Bacteria,1GGRK@1117|Cyanobacteria,3VMK4@52604|Pleurocapsales 1117|Cyanobacteria Q methyltransferase - - - - - - - - - - - - - GDHHQS3_k127_1339391_2 225937.HP15_440 9.223e-80 280.0 COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria,469U7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_1339391_8 247634.GPB2148_787 4.361e-25 108.0 COG3809@1|root,COG3809@2|Bacteria,1N33W@1224|Proteobacteria,1SASZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transcription factor zinc-finger - - - - - - - - - - - - zf-TFIIB GDHHQS3_k127_1339391_1 118161.KB235922_gene1210 1.368e-209 666.0 COG2072@1|root,COG2072@2|Bacteria,1G8W3@1117|Cyanobacteria 1117|Cyanobacteria C Flavin-binding monooxygenase-like - - - - - - - - - - - - FMO-like GDHHQS3_k127_1339391_4 247634.GPB2148_501 3.999e-56 205.0 COG1285@1|root,COG1285@2|Bacteria 2|Bacteria E pathogenesis XK27_05505 - - - - - - - - - - - DUF4956 GDHHQS3_k127_1339391_6 1123054.KB907728_gene3043 1.716e-29 134.0 2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 GDHHQS3_k127_1339391_3 1121013.P873_14170 6.993e-64 238.0 29SNM@1|root,30DU7@2|Bacteria,1RGQV@1224|Proteobacteria,1S54D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 GDHHQS3_k127_1339391_0 404589.Anae109_4277 1.081e-224 708.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42RBW@68525|delta/epsilon subdivisions,2X5G8@28221|Deltaproteobacteria,2Z35G@29|Myxococcales 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_1341590_16 551789.ATVJ01000001_gene2425 6.784e-17 86.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,2UAC1@28211|Alphaproteobacteria,43WT7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_7,TPR_8 GDHHQS3_k127_1341590_13 1122603.ATVI01000005_gene3549 2.423e-43 167.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1X6TU@135614|Xanthomonadales 135614|Xanthomonadales D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 GDHHQS3_k127_1341590_4 1122603.ATVI01000005_gene3550 8.93e-126 417.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XCFT@135614|Xanthomonadales 135614|Xanthomonadales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB GDHHQS3_k127_1341590_11 1535422.ND16A_2142 9.594e-46 171.0 COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 GDHHQS3_k127_1341590_7 1121374.KB891575_gene1433 2.452e-95 326.0 COG0738@1|root,COG0738@2|Bacteria,1QX0S@1224|Proteobacteria,1T32Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Major facilitator superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_1341590_10 1283300.ATXB01000001_gene582 5.289e-60 214.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1XFME@135618|Methylococcales 135618|Methylococcales C Cytochrome b/b6/petB - - - - - - - - - - - - Ni_hydr_CYTB GDHHQS3_k127_1341590_12 1280944.HY17_02730 1.028e-44 170.0 COG2771@1|root,COG2771@2|Bacteria,1QU5E@1224|Proteobacteria,2TW0B@28211|Alphaproteobacteria,43YDM@69657|Hyphomonadaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE GDHHQS3_k127_1341590_15 1249627.D779_3682 1.365e-29 120.0 COG1396@1|root,COG1396@2|Bacteria,1MZQK@1224|Proteobacteria,1SFEY@1236|Gammaproteobacteria,1WZ36@135613|Chromatiales 135613|Chromatiales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 GDHHQS3_k127_1341590_0 1082933.MEA186_07699 3.078e-299 931.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,43KPP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CP Proton-conducting membrane transporter - - - - - - - - - - - - Proton_antipo_M GDHHQS3_k127_1341590_3 536019.Mesop_2131 4.711e-139 455.0 COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2U0GZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH dehydrogenase hycD - - - - - - - - - - - NADHdh GDHHQS3_k127_1341590_6 1532558.JL39_17395 1.717e-102 336.0 COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2TUAC@28211|Alphaproteobacteria,4BA7A@82115|Rhizobiaceae 28211|Alphaproteobacteria C COG4237 Hydrogenase 4 membrane component (E) hyfE - - ko:K12140 - - - - ko00000,ko01000 - - - - GDHHQS3_k127_1341590_1 1082933.MEA186_07714 5.318e-248 771.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2TSRU@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) hyfF - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M GDHHQS3_k127_1341590_2 536019.Mesop_2128 6.495e-233 729.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2TRE0@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH-ubiquinone oxidoreductase chain 49kDa hycE - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases GDHHQS3_k127_1341590_9 398525.KB900701_gene3352 6.054e-81 273.0 COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2U279@28211|Alphaproteobacteria,3JTGI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hycG - - - - - - - - - - - Oxidored_q6 GDHHQS3_k127_1341590_5 998674.ATTE01000001_gene1237 3.834e-117 384.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1S2TN@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the arginase family argI - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase GDHHQS3_k127_1341590_8 479434.Sthe_0453 4.318e-84 291.0 COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi,27Z25@189775|Thermomicrobia 189775|Thermomicrobia S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GDHHQS3_k127_1341590_14 118168.MC7420_1677 2.907e-33 136.0 COG1335@1|root,COG1335@2|Bacteria,1GAHK@1117|Cyanobacteria 1117|Cyanobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase GDHHQS3_k127_1345268_11 388051.AUFE01000004_gene926 2.534e-38 151.0 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2VUFU@28216|Betaproteobacteria 28216|Betaproteobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2 GDHHQS3_k127_1345268_6 572477.Alvin_1296 3.644e-102 344.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales 135613|Chromatiales S Pfam:UPF0118 - - - - - - - - - - - - AI-2E_transport GDHHQS3_k127_1345268_3 1300345.LF41_1864 4.995e-122 410.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales 135614|Xanthomonadales S Adenylate cyclase - - - - - - - - - - - - TPR_16 GDHHQS3_k127_1345268_13 1056820.KB900645_gene3444 1.088e-07 56.0 2AU92@1|root,31JWD@2|Bacteria,1QHPA@1224|Proteobacteria,1TFD1@1236|Gammaproteobacteria,2PQHM@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF4404) - - - - - - - - - - - - DUF4404 GDHHQS3_k127_1345268_5 1280954.HPO_05877 6.938e-106 357.0 COG1887@1|root,COG1887@2|Bacteria,1R476@1224|Proteobacteria,2U4I9@28211|Alphaproteobacteria,43ZN9@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - - - - - - - - - - Glyphos_transf GDHHQS3_k127_1345268_9 1455608.JDTH01000002_gene1395 2.28e-42 158.0 arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria 183963|Halobacteria S flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx GDHHQS3_k127_1345268_7 1538295.JY96_00950 8.016e-87 293.0 COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria,2VQNR@28216|Betaproteobacteria,1KNQ5@119065|unclassified Burkholderiales 28216|Betaproteobacteria Q ubiE/COQ5 methyltransferase family ycgJ - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_1345268_4 1123257.AUFV01000008_gene678 8.8e-110 367.0 COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,1RPNK@1236|Gammaproteobacteria,1X4WP@135614|Xanthomonadales 135614|Xanthomonadales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport GDHHQS3_k127_1345268_12 234267.Acid_6770 6.02e-31 140.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,3Y77J@57723|Acidobacteria 57723|Acidobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - DUF1736,TPR_11,TPR_16 GDHHQS3_k127_1345268_2 519989.ECTPHS_02039 2.918e-124 406.0 COG0524@1|root,COG0524@2|Bacteria,1PG62@1224|Proteobacteria,1RXRC@1236|Gammaproteobacteria,1X1NV@135613|Chromatiales 135613|Chromatiales G pfkB family carbohydrate kinase - - - - - - - - - - - - PfkB GDHHQS3_k127_1345268_0 1500890.JQNL01000001_gene2501 3.857e-181 574.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1X3UK@135614|Xanthomonadales 135614|Xanthomonadales D Rod shape-determining protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl GDHHQS3_k127_1345268_8 1384054.N790_10785 1.138e-62 226.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1X3A4@135614|Xanthomonadales 135614|Xanthomonadales M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC GDHHQS3_k127_1345268_10 1234364.AMSF01000090_gene2471 9.344e-41 156.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S26R@1236|Gammaproteobacteria,1X6PV@135614|Xanthomonadales 135614|Xanthomonadales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD GDHHQS3_k127_1345268_1 666685.R2APBS1_0398 1.461e-155 506.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1X374@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase GDHHQS3_k127_1354212_2 1385517.N800_09360 2.802e-74 257.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales 135614|Xanthomonadales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 GDHHQS3_k127_1354212_0 1384054.N790_06695 6.439e-80 278.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1X4YZ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase GDHHQS3_k127_1354212_3 1500890.JQNL01000001_gene1966 1.407e-38 153.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S953@1236|Gammaproteobacteria,1X35M@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09921 - - - - ko00000 - - - DUF484 GDHHQS3_k127_1354212_1 1049564.TevJSym_at00460 5.551e-75 260.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1J4JX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GDHHQS3_k127_1355757_4 1202962.KB907161_gene278 4.776e-65 229.0 COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,1RR38@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent phosphohydrolase yedJ - - ko:K06950 - - - - ko00000 - - - HD GDHHQS3_k127_1355757_5 42256.RradSPS_2920 2.42e-48 181.0 COG0590@1|root,COG0590@2|Bacteria,2I9KR@201174|Actinobacteria 201174|Actinobacteria FJ CMP dCMP deaminase, zinc-binding - - - - - - - - - - - - dCMP_cyt_deam_1 GDHHQS3_k127_1355757_2 1207076.ALAT01000130_gene3163 9.124e-74 257.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1Z17K@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind GDHHQS3_k127_1355757_0 472759.Nhal_0436 1.008e-239 760.0 COG0557@1|root,COG2345@1|root,COG0557@2|Bacteria,COG2345@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 GDHHQS3_k127_1355757_3 566466.NOR53_3173 2.216e-71 252.0 COG2267@1|root,COG2267@2|Bacteria,1QVW4@1224|Proteobacteria,1T2Y5@1236|Gammaproteobacteria,1J9P7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Esterase,Hydrolase_4 GDHHQS3_k127_1355757_1 565045.NOR51B_2247 1.282e-159 519.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T1MR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_1390924_0 1207076.ALAT01000184_gene2708 0.0 1491.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1Z29S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 GDHHQS3_k127_1390924_3 1286106.MPL1_11628 2.332e-61 223.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,460JH@72273|Thiotrichales 72273|Thiotrichales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 GDHHQS3_k127_1390924_1 1249627.D779_1675 1.308e-104 349.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales 135613|Chromatiales L TIGRFAM Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GDHHQS3_k127_1390924_2 323261.Noc_0611 3.895e-64 236.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1X1GJ@135613|Chromatiales 135613|Chromatiales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 GDHHQS3_k127_1390924_4 1026882.MAMP_01332 1.417e-42 164.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C GDHHQS3_k127_1390924_5 1415780.JPOG01000001_gene2647 2.312e-36 142.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD GDHHQS3_k127_1393203_0 1122603.ATVI01000004_gene1823 2.379e-209 660.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1XCGK@135614|Xanthomonadales 135614|Xanthomonadales L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DUF772 GDHHQS3_k127_1393203_1 89187.ISM_10381 1.377e-55 198.0 COG0526@1|root,COG0526@2|Bacteria,1RDJB@1224|Proteobacteria,2V3RY@28211|Alphaproteobacteria,46S26@74030|Roseovarius 28211|Alphaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - - GDHHQS3_k127_1402129_12 1335757.SPICUR_07705 8.889e-23 100.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1WYWV@135613|Chromatiales 135613|Chromatiales S Stringent starvation protein B - - - ko:K03600 - - - - ko00000,ko03021 - - - SspB GDHHQS3_k127_1402129_14 768671.ThimaDRAFT_0532 3.042e-05 50.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SGKD@1236|Gammaproteobacteria,1WYKI@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 GDHHQS3_k127_1402129_10 1163408.UU9_15677 4.077e-36 145.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1SASJ@1236|Gammaproteobacteria,1X63Q@135614|Xanthomonadales 135614|Xanthomonadales S SMR domain protein - - - - - - - - - - - - Smr GDHHQS3_k127_1402129_3 1384054.N790_11350 1.76e-116 385.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1X3JC@135614|Xanthomonadales 135614|Xanthomonadales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE GDHHQS3_k127_1402129_7 1123253.AUBD01000008_gene336 1.521e-72 253.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT GDHHQS3_k127_1402129_8 1121013.P873_06420 1.632e-56 211.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1X4WB@135614|Xanthomonadales 135614|Xanthomonadales DM membrane nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 GDHHQS3_k127_1402129_5 768671.ThimaDRAFT_2263 3.69e-90 307.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales 135613|Chromatiales K TIGRFAM RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 GDHHQS3_k127_1402129_11 1163407.UU7_13298 1.007e-24 110.0 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,1X7EH@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 GDHHQS3_k127_1402129_13 2340.JV46_08480 1.323e-19 93.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1J6YZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY GDHHQS3_k127_1402129_6 1122194.AUHU01000010_gene3065 4.222e-76 262.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,464RW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ GDHHQS3_k127_1402129_0 396588.Tgr7_0981 1.212e-298 927.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 GDHHQS3_k127_1402129_4 349124.Hhal_1769 1.11e-91 309.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind GDHHQS3_k127_1402129_2 519989.ECTPHS_07022 6.308e-177 564.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales 135613|Chromatiales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GDHHQS3_k127_1402129_1 1123073.KB899245_gene60 7.953e-185 584.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_1402129_9 1123253.AUBD01000007_gene699 1.752e-47 171.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1X49B@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GDHHQS3_k127_1402460_1 396588.Tgr7_1157 6.241e-100 336.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 GDHHQS3_k127_1402460_0 1286106.MPL1_01368 3.414e-119 394.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,45ZPM@72273|Thiotrichales 72273|Thiotrichales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 GDHHQS3_k127_1402460_2 1122185.N792_03085 4.239e-76 268.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales 135614|Xanthomonadales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 GDHHQS3_k127_141230_3 653733.Selin_0267 4.732e-47 170.0 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res GDHHQS3_k127_141230_1 338969.Rfer_1962 3.856e-75 258.0 COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,4AE1T@80864|Comamonadaceae 28216|Betaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA GDHHQS3_k127_141230_0 768671.ThimaDRAFT_0808 4.411e-190 603.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1WXN7@135613|Chromatiales 135613|Chromatiales P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp GDHHQS3_k127_141230_2 204773.HEAR2507 3.921e-61 213.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA GDHHQS3_k127_1420460_5 335543.Sfum_2433 4.314e-106 366.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N GDHHQS3_k127_1420460_12 65393.PCC7424_0056 8.512e-78 288.0 COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1G3AY@1117|Cyanobacteria,3KJD0@43988|Cyanothece 1117|Cyanobacteria PT Sulfate transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp,cNMP_binding GDHHQS3_k127_1420460_34 1240349.ANGC01000020_gene4267 0.000801 49.0 2B6GM@1|root,305KJ@2|Bacteria,2HJ9P@201174|Actinobacteria,4G5ZZ@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1420460_3 565045.NOR51B_513 6.773e-134 454.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1J4UG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_1420460_1 1121374.KB891589_gene75 1.471e-157 514.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_1420460_0 392499.Swit_1064 1.343e-168 546.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,2K0QC@204457|Sphingomonadales 204457|Sphingomonadales E Oxidoreductase - - 1.1.5.9 ko:K19813 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R00305 RC00066 ko00000,ko00001,ko01000 - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 GDHHQS3_k127_1420460_24 1408433.JHXV01000027_gene3706 2.132e-39 158.0 COG0702@1|root,COG0702@2|Bacteria,4NFUX@976|Bacteroidetes 976|Bacteroidetes GM SPTR NmrA family protein - - - - - - - - - - - - NAD_binding_10 GDHHQS3_k127_1420460_23 1121374.KB891589_gene74 5.887e-46 174.0 2E7KM@1|root,3322M@2|Bacteria,1N7XR@1224|Proteobacteria,1SQEB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1420460_2 221288.JH992901_gene2438 2.388e-138 452.0 COG1960@1|root,COG1960@2|Bacteria,1G3AS@1117|Cyanobacteria,1JM6F@1189|Stigonemataceae 1117|Cyanobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_1420460_31 251221.35213314 7.969e-16 80.0 COG2329@1|root,COG2329@2|Bacteria 2|Bacteria S heme oxygenase (decyclizing) activity - - 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM,ydhR GDHHQS3_k127_1420460_28 298654.FraEuI1c_2884 5.708e-26 115.0 COG5517@1|root,COG5517@2|Bacteria,2GR5G@201174|Actinobacteria 201174|Actinobacteria Q SnoaL-like domain - - - - - - - - - - - - SnoaL_4 GDHHQS3_k127_1420460_15 1500893.JQNB01000001_gene2677 2.219e-73 277.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,1XDD8@135614|Xanthomonadales 135614|Xanthomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_1420460_30 340099.Teth39_1975 4.019e-23 109.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,42G3H@68295|Thermoanaerobacterales 186801|Clostridia K Transcriptional regulator IclR - - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR GDHHQS3_k127_1420460_16 172088.AUGA01000012_gene7214 3.619e-73 255.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3JRYC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the ABC transporter superfamily MA20_20675 - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GDHHQS3_k127_1420460_6 1144310.PMI07_005578 1.216e-103 347.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,4B7FM@82115|Rhizobiaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY GDHHQS3_k127_1420460_11 1144310.PMI07_005577 6.892e-89 303.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria 1224|Proteobacteria EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N GDHHQS3_k127_1420460_9 381666.H16_A2950 8.065e-91 308.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VR1Q@28216|Betaproteobacteria,1K78Q@119060|Burkholderiaceae 28216|Betaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 GDHHQS3_k127_1420460_22 1123060.JONP01000036_gene3557 3.37e-57 212.0 COG0329@1|root,COG0329@2|Bacteria,1NEJ4@1224|Proteobacteria,2UIK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_1420460_18 1123060.JONP01000036_gene3557 1.481e-67 245.0 COG0329@1|root,COG0329@2|Bacteria,1NEJ4@1224|Proteobacteria,2UIK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_1420460_32 47839.CCAU010000019_gene3519 4.112e-14 78.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 GDHHQS3_k127_1420460_19 1123060.JONP01000036_gene3557 5.044e-64 235.0 COG0329@1|root,COG0329@2|Bacteria,1NEJ4@1224|Proteobacteria,2UIK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_1420460_33 1089544.KB912942_gene1035 0.0001144 53.0 COG2267@1|root,COG2267@2|Bacteria,2I3P3@201174|Actinobacteria,4E207@85010|Pseudonocardiales 201174|Actinobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - - GDHHQS3_k127_1420460_10 1144310.PMI07_005575 1.443e-89 318.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,4BE6T@82115|Rhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 GDHHQS3_k127_1420460_20 584708.Apau_1382 1.01e-60 219.0 COG4689@1|root,COG4689@2|Bacteria,3TBXM@508458|Synergistetes 508458|Synergistetes Q COGs COG4689 Acetoacetate decarboxylase - - - - - - - - - - - - ADC GDHHQS3_k127_1420460_29 715226.ABI_40220 2.695e-24 118.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2KF7A@204458|Caulobacterales 204458|Caulobacterales H Belongs to the UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD GDHHQS3_k127_1420460_13 1123060.JONP01000036_gene3557 2.602e-77 274.0 COG0329@1|root,COG0329@2|Bacteria,1NEJ4@1224|Proteobacteria,2UIK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_1420460_4 1280949.HAD_10030 2.136e-119 413.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_1420460_27 551789.ATVJ01000001_gene1967 9.824e-30 125.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TSRP@28211|Alphaproteobacteria,43X75@69657|Hyphomonadaceae 28211|Alphaproteobacteria T signal transduction histidine kinase divJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07716,ko:K11357 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4 GDHHQS3_k127_1420460_25 1116369.KB890025_gene5038 2.933e-37 152.0 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,2U0V4@28211|Alphaproteobacteria,43JHA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - ko:K16516 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate GDHHQS3_k127_1420460_8 1535287.JP74_06560 1.828e-93 317.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,3N8K7@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR1 - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C GDHHQS3_k127_1420460_14 1123060.JONP01000036_gene3557 4.821e-76 268.0 COG0329@1|root,COG0329@2|Bacteria,1NEJ4@1224|Proteobacteria,2UIK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_1420460_17 1118054.CAGW01000061_gene2426 5.759e-70 246.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26RRC@186822|Paenibacillaceae 91061|Bacilli E ABC transporter - - - - - - - - - - - - ABC_tran GDHHQS3_k127_1420460_21 571166.KI421509_gene953 3.955e-59 221.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VEYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria E branched-chain amino acid MA20_09940 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C GDHHQS3_k127_1420460_7 1217720.ALOX01000127_gene1182 8.559e-95 334.0 COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2TTC6@28211|Alphaproteobacteria,2JQDN@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 GDHHQS3_k127_1420460_26 1380394.JADL01000014_gene175 1.489e-30 135.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,2JWU0@204441|Rhodospirillales 204441|Rhodospirillales E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 GDHHQS3_k127_1430708_4 203122.Sde_3895 9.839e-31 127.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 GDHHQS3_k127_1430708_6 566466.NOR53_455 6.01e-27 126.0 2EFI3@1|root,339AJ@2|Bacteria,1N96F@1224|Proteobacteria,1SE0P@1236|Gammaproteobacteria,1J9XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 GDHHQS3_k127_1430708_5 472759.Nhal_2917 1.21e-29 131.0 arCOG11477@1|root,32TJG@2|Bacteria,1MYXX@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 GDHHQS3_k127_1430708_3 1442599.JAAN01000012_gene156 5.79e-35 138.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SDD5@1236|Gammaproteobacteria,1X6IQ@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 GDHHQS3_k127_1430708_2 1215092.PA6_017_00590 1.104e-50 190.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1YDP2@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos GDHHQS3_k127_1430708_8 436717.AOLE_01920 3.661e-14 76.0 COG1983@1|root,COG1983@2|Bacteria,1NAUA@1224|Proteobacteria,1SD7E@1236|Gammaproteobacteria,3NPCM@468|Moraxellaceae 1236|Gammaproteobacteria KT PspC domain - - - - - - - - - - - - PspC GDHHQS3_k127_1430708_7 1070319.CAGGBEG34_200088 6.867e-24 106.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KA31@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM Rubredoxin-type Fe(Cys)4 protein rubA - - - - - - - - - - - Rubredoxin GDHHQS3_k127_1430708_1 666685.R2APBS1_0385 1.378e-57 209.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1X6BT@135614|Xanthomonadales 135614|Xanthomonadales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI GDHHQS3_k127_1430708_0 396588.Tgr7_2421 3.238e-170 541.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales 135613|Chromatiales H PFAM Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_143314_0 1278073.MYSTI_06476 3.116e-102 351.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales 28221|Deltaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 GDHHQS3_k127_143314_2 1237149.C900_02972 4.748e-13 80.0 COG4977@1|root,COG4977@2|Bacteria,4PKQX@976|Bacteroidetes,47Y96@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 GDHHQS3_k127_143314_1 450851.PHZ_c2012 6.136e-71 246.0 COG4774@1|root,COG4774@2|Bacteria,1R6E9@1224|Proteobacteria 1224|Proteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_1455515_4 1085623.GNIT_3183 7.357e-69 235.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,4660Y@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit hyuA - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B GDHHQS3_k127_1455515_3 1411685.U062_00432 3.437e-125 407.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1J7YX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E HMGL-like - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like GDHHQS3_k127_1455515_2 1120953.AUBH01000007_gene1695 3.078e-199 627.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,46A8R@72275|Alteromonadaceae 1236|Gammaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 GDHHQS3_k127_1455515_5 644283.Micau_3754 5.06e-49 183.0 COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria,4DG68@85008|Micromonosporales 201174|Actinobacteria K FCD - - - - - - - - - - - - FCD,GntR GDHHQS3_k127_1455515_0 314285.KT71_18921 0.0 1075.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1RYC0@1236|Gammaproteobacteria,1J7WD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_1455515_6 1485544.JQKP01000004_gene546 4.068e-48 177.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales 28216|Betaproteobacteria E ACT domain ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C GDHHQS3_k127_1455515_1 1415780.JPOG01000001_gene1540 3.27e-245 765.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales 135614|Xanthomonadales E Acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_1480140_3 392499.Swit_1698 2.129e-59 213.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GDHHQS3_k127_1480140_5 382464.ABSI01000006_gene862 8.139e-13 75.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 4.4.1.5 ko:K01759,ko:K08234 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase GDHHQS3_k127_1480140_1 493475.GARC_1700 9.54e-104 349.0 COG5505@1|root,COG5505@2|Bacteria,1RAF4@1224|Proteobacteria,1RW3U@1236|Gammaproteobacteria,46B0T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 GDHHQS3_k127_1480140_2 1396418.BATQ01000170_gene2658 1.997e-67 246.0 COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia,2IVU2@203494|Verrucomicrobiae 203494|Verrucomicrobiae KT Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B_2,Response_reg GDHHQS3_k127_1480140_0 1122185.N792_12380 5.812e-123 422.0 COG1807@1|root,COG1807@2|Bacteria,1QC11@1224|Proteobacteria,1T7NQ@1236|Gammaproteobacteria,1X9H6@135614|Xanthomonadales 135614|Xanthomonadales M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - GDHHQS3_k127_1480140_4 1205753.A989_02465 1.752e-32 131.0 COG2246@1|root,COG2246@2|Bacteria,1RBFH@1224|Proteobacteria,1T6UH@1236|Gammaproteobacteria,1X7GG@135614|Xanthomonadales 135614|Xanthomonadales S GtrA-like protein - - - - - - - - - - - - GtrA GDHHQS3_k127_1533610_0 396588.Tgr7_0817 0.0 1028.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N GDHHQS3_k127_1533610_2 1163407.UU7_06203 2.488e-120 397.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1X3M7@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_1533610_3 349124.Hhal_1470 8.757e-110 362.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1WVX8@135613|Chromatiales 135613|Chromatiales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 GDHHQS3_k127_1533610_1 187272.Mlg_1865 1.189e-167 546.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 GDHHQS3_k127_1555853_1 1280949.HAD_14109 4.946e-146 466.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases MA20_01050 - 1.17.1.10 ko:K15022 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 M00377 R00134 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3 GDHHQS3_k127_1555853_5 1537994.JQFW01000050_gene2454 2.567e-11 70.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RUS7@1236|Gammaproteobacteria,46CAV@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_1555853_4 1331060.RLDS_01755 7.305e-27 115.0 COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MAPEG family MA20_30600 - - - - - - - - - - - MAPEG GDHHQS3_k127_1555853_0 266117.Rxyl_0536 4.174e-282 893.0 COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria 201174|Actinobacteria G D-galactarate dehydratase Altronate - - 4.2.1.42,4.2.1.7 ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00631 R01540,R05608 RC00543 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF GDHHQS3_k127_1555853_3 1403819.BATR01000096_gene3103 5.4e-102 338.0 COG3970@1|root,COG3970@2|Bacteria,46S9N@74201|Verrucomicrobia,2IUA6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase GDHHQS3_k127_1555853_2 246197.MXAN_2850 4.204e-145 472.0 COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_156115_2 1249627.D779_3446 1.742e-09 62.0 COG3151@1|root,COG3151@2|Bacteria,1MYG8@1224|Proteobacteria,1S7P6@1236|Gammaproteobacteria,1X27Y@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1249) - - - ko:K09920 - - - - ko00000 - - - DUF1249 GDHHQS3_k127_156115_1 1121015.N789_12450 4.945e-97 325.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1X41E@135614|Xanthomonadales 135614|Xanthomonadales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase GDHHQS3_k127_156115_0 1249627.D779_0547 3.74e-154 500.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N GDHHQS3_k127_1570494_1 1234364.AMSF01000037_gene198 1.035e-79 276.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X462@135614|Xanthomonadales 135614|Xanthomonadales M Male sterility protein - - - - - - - - - - - - Epimerase GDHHQS3_k127_1570494_2 1384054.N790_04900 3.235e-49 189.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,1X4Y6@135614|Xanthomonadales 135614|Xanthomonadales V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 GDHHQS3_k127_1570494_0 1121015.N789_10555 2.093e-110 362.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1X54A@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the peptidase M17 family pepA2 - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 GDHHQS3_k127_159765_1 347834.RHE_CH00762 7.062e-139 446.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2TR8G@28211|Alphaproteobacteria,4B6ZB@82115|Rhizobiaceae 28211|Alphaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd GDHHQS3_k127_159765_0 1121013.P873_00620 6.89e-167 535.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1X4NT@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GDHHQS3_k127_159765_2 1116472.MGMO_4c00250 6.609e-133 432.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XE9Q@135618|Methylococcales 135618|Methylococcales M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase GDHHQS3_k127_159765_4 1384056.N787_00690 1.805e-60 219.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XC7R@135614|Xanthomonadales 135614|Xanthomonadales O Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N GDHHQS3_k127_159765_5 29581.BW37_04527 1.265e-43 162.0 COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,2WCBP@28216|Betaproteobacteria,477A4@75682|Oxalobacteraceae 28216|Betaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR GDHHQS3_k127_159765_3 1123073.KB899242_gene1422 9.044e-87 291.0 COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria,1X3B4@135614|Xanthomonadales 135614|Xanthomonadales V abc transporter atp-binding protein nodI - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_1610552_35 933262.AXAM01000009_gene1469 3.397e-05 56.0 COG5338@1|root,COG5338@2|Bacteria,1N5KN@1224|Proteobacteria,42UYK@68525|delta/epsilon subdivisions,2WQAA@28221|Deltaproteobacteria,2MMEY@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - BBP2_2 GDHHQS3_k127_1610552_26 1121441.AUCX01000008_gene2153 2.079e-33 137.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria,2MAXP@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Polysaccharide export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB GDHHQS3_k127_1610552_21 56780.SYN_00780 4.007e-47 188.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42M2D@68525|delta/epsilon subdivisions,2WJU6@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Lipopolysaccharide biosynthesis protein wzc1 - - - - - - - - - - - Wzz GDHHQS3_k127_1610552_31 118163.Ple7327_2646 2.343e-18 94.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G00H@1117|Cyanobacteria,3VIKG@52604|Pleurocapsales 1117|Cyanobacteria D CobQ CobB MinD ParA nucleotide binding domain - - - - - - - - - - - - AAA_31,GNVR,ParA,Wzz GDHHQS3_k127_1610552_19 1286631.X805_14640 5.015e-54 207.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,1KJZ4@119065|unclassified Burkholderiales 28216|Betaproteobacteria M TIGRFAM sugar transferase, PEP-CTERM system associated wcaJ - 2.7.8.40 ko:K21303 - - - - ko00000,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3 GDHHQS3_k127_1610552_4 1183438.GKIL_0464 2.713e-145 475.0 COG0677@1|root,COG0677@2|Bacteria,1G4FW@1117|Cyanobacteria 1117|Cyanobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GDHHQS3_k127_1610552_36 1044.EH31_15455 0.0003212 53.0 COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria,2JZV1@204457|Sphingomonadales 204457|Sphingomonadales M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - - - - - - - - - - Wzy_C GDHHQS3_k127_1610552_17 378806.STAUR_0612 1.018e-56 217.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_1610552_22 1303518.CCALI_02461 4.919e-46 182.0 COG5653@1|root,COG5653@2|Bacteria 2|Bacteria M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 GDHHQS3_k127_1610552_24 290397.Adeh_2761 7.529e-40 163.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,430CQ@68525|delta/epsilon subdivisions,2WW16@28221|Deltaproteobacteria,2Z33A@29|Myxococcales 28221|Deltaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 GDHHQS3_k127_1610552_23 1297742.A176_02653 7.598e-46 185.0 COG2244@1|root,COG2244@2|Bacteria,1P0EB@1224|Proteobacteria,431IR@68525|delta/epsilon subdivisions,2WW7D@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C GDHHQS3_k127_1610552_1 1499967.BAYZ01000026_gene1631 9.301e-170 555.0 COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria 2|Bacteria E PFAM asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GDHHQS3_k127_1610552_13 1267535.KB906767_gene2188 8.489e-82 286.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_1610552_12 398512.JQKC01000006_gene681 2.726e-86 314.0 COG5360@1|root,COG5360@2|Bacteria,1UZKY@1239|Firmicutes,25CFT@186801|Clostridia 186801|Clostridia S Heparinase II/III N-terminus - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N GDHHQS3_k127_1610552_2 1267535.KB906767_gene5013 1.004e-156 517.0 COG0367@1|root,COG0367@2|Bacteria,3Y75N@57723|Acidobacteria 57723|Acidobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GDHHQS3_k127_1610552_16 926566.Terro_2831 1.866e-73 268.0 COG0438@1|root,COG0438@2|Bacteria,3Y64B@57723|Acidobacteria 57723|Acidobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 GDHHQS3_k127_1610552_14 1163408.UU9_04152 1.158e-77 269.0 COG0223@1|root,COG0223@2|Bacteria,1N4W3@1224|Proteobacteria 1224|Proteobacteria J COG0223 Methionyl-tRNA formyltransferase - - - - - - - - - - - - Formyl_trans_N GDHHQS3_k127_1610552_20 234267.Acid_7807 4.954e-52 196.0 COG0726@1|root,COG0726@2|Bacteria,3Y95Z@57723|Acidobacteria 57723|Acidobacteria G PFAM Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 GDHHQS3_k127_1610552_6 879212.DespoDRAFT_03349 1.375e-135 446.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2MHMX@213118|Desulfobacterales 28221|Deltaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GDHHQS3_k127_1610552_15 75379.Tint_1508 2.094e-77 275.0 COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,2VRXN@28216|Betaproteobacteria,1KKYM@119065|unclassified Burkholderiales 28216|Betaproteobacteria M glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 GDHHQS3_k127_1610552_11 1122917.KB899662_gene2150 3.403e-96 328.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,26RRS@186822|Paenibacillaceae 91061|Bacilli GM GDP-mannose 4,6 dehydratase - - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase GDHHQS3_k127_1610552_30 1237149.C900_03408 6.7e-20 106.0 COG2755@1|root,COG3209@1|root,COG4733@1|root,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,4NJGD@976|Bacteroidetes,47VZA@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 GDHHQS3_k127_1610552_29 686340.Metal_2794 2.252e-26 117.0 COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,1SCWT@1236|Gammaproteobacteria,1XFTA@135618|Methylococcales 135618|Methylococcales T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2 GDHHQS3_k127_1610552_28 330214.NIDE1163 1.893e-27 122.0 COG4585@1|root,COG4585@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07683 ko02020,map02020 M00483 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - ABC_sub_bind,GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9 GDHHQS3_k127_1610552_18 1267535.KB906767_gene4776 3.685e-56 204.0 COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia 204432|Acidobacteriia T PFAM Response regulator receiver domain - - - - - - - - - - - - GerE,Response_reg GDHHQS3_k127_1610552_27 671143.DAMO_1129 1.623e-30 132.0 COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria 2|Bacteria T Two component transcriptional regulator, winged helix family - - - ko:K07658,ko:K07668 ko02020,map02020 M00434,M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GDHHQS3_k127_1610552_25 1283300.ATXB01000002_gene2888 1.021e-36 153.0 2DP87@1|root,330Z8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1610552_9 378806.STAUR_3664 3.59e-113 381.0 COG5653@1|root,COG5653@2|Bacteria,1NCB6@1224|Proteobacteria,430DK@68525|delta/epsilon subdivisions,2WVKU@28221|Deltaproteobacteria,2YZ7B@29|Myxococcales 28221|Deltaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 GDHHQS3_k127_1610552_3 1278073.MYSTI_04709 1.134e-152 497.0 COG0399@1|root,COG0399@2|Bacteria,1REP8@1224|Proteobacteria,42S4Y@68525|delta/epsilon subdivisions,2WNVT@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 GDHHQS3_k127_1610552_34 500640.CIT292_11168 1.624e-06 53.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,3WYTX@544|Citrobacter 1236|Gammaproteobacteria S CsbD-like yjbJ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - CsbD GDHHQS3_k127_1610552_5 1415778.JQMM01000001_gene2108 1.002e-138 452.0 COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,1RQYF@1236|Gammaproteobacteria,1J4ED@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG4553 Poly-beta-hydroxyalkanoate depolymerase phaZ - 3.1.1.75 ko:K05973 ko00650,map00650 - R05118 - ko00000,ko00001,ko01000 - - - PHB_depo_C GDHHQS3_k127_1610552_0 1395571.TMS3_0105355 3.573e-186 597.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I poly(R)-hydroxyalkanoic acid synthase phaC1 - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N GDHHQS3_k127_1610552_7 1415778.JQMM01000001_gene770 1.113e-128 435.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J6E9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec GDHHQS3_k127_1610552_10 1121948.AUAC01000005_gene2012 1.231e-97 346.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,2TWZ1@28211|Alphaproteobacteria,44159@69657|Hyphomonadaceae 28211|Alphaproteobacteria K cAMP biosynthetic process - - - - - - - - - - - - Guanylate_cyc,Trans_reg_C GDHHQS3_k127_1610552_8 887062.HGR_04393 1.414e-115 386.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,4AIFH@80864|Comamonadaceae 28216|Betaproteobacteria P Divalent cation transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N GDHHQS3_k127_1610552_33 1535422.ND16A_1877 7.859e-09 57.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,2Q73E@267889|Colwelliaceae 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 GDHHQS3_k127_1625104_5 570952.ATVH01000017_gene1822 1.201e-08 57.0 COG2801@1|root,COG2801@2|Bacteria,1NAXT@1224|Proteobacteria,2UVUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - - GDHHQS3_k127_1625104_1 748247.AZKH_4576 6.636e-174 556.0 COG3177@1|root,COG3177@2|Bacteria,1QRKG@1224|Proteobacteria,2VPMZ@28216|Betaproteobacteria 28216|Betaproteobacteria S Fic/DOC family - - - - - - - - - - - - Fic,HTH_DeoR GDHHQS3_k127_1625104_0 365044.Pnap_0395 4.561e-185 588.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria,4A9WX@80864|Comamonadaceae 28216|Betaproteobacteria G Glucose / Sorbosone dehydrogenase sndH - - - - - - - - - - - GSDH GDHHQS3_k127_1625104_4 1288494.EBAPG3_15050 2.55e-13 71.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria 28216|Betaproteobacteria P Metallo-beta-lactamase superfamily - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B GDHHQS3_k127_1625104_3 1288494.EBAPG3_15050 5.417e-14 76.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria 28216|Betaproteobacteria P Metallo-beta-lactamase superfamily - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B GDHHQS3_k127_1625104_2 261292.Nit79A3_3543 1.166e-170 546.0 COG1352@1|root,COG2201@1|root,COG3352@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3352@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria,372IJ@32003|Nitrosomonadales 28216|Betaproteobacteria NT PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,PAS_10 GDHHQS3_k127_1628739_4 930169.B5T_00058 4.137e-26 109.0 COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,1XJVV@135619|Oceanospirillales 135619|Oceanospirillales G Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C GDHHQS3_k127_1628739_1 631362.Thi970DRAFT_04389 9.424e-66 232.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding GDHHQS3_k127_1628739_0 1166948.JPZL01000003_gene765 1.298e-170 547.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1XHZ4@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM GDHHQS3_k127_1628739_2 1444770.AF72_06040 4.458e-56 200.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1X6I0@135614|Xanthomonadales 135614|Xanthomonadales H synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS GDHHQS3_k127_1628739_3 1227497.C491_14577 2.038e-26 117.0 COG3369@1|root,arCOG03175@1|root,arCOG03174@2157|Archaea,arCOG03175@2157|Archaea,2Y1YC@28890|Euryarchaeota,23ZKU@183963|Halobacteria 183963|Halobacteria S CDGSH-type zinc finger. Function unknown. - - - - - - - - - - - - Fer4_19,zf-CDGSH GDHHQS3_k127_1628739_5 1217714.F975_00743 2.038e-09 59.0 COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,1SBKN@1236|Gammaproteobacteria,3NM03@468|Moraxellaceae 1236|Gammaproteobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA GDHHQS3_k127_1648794_1 1283300.ATXB01000001_gene2342 9.365e-19 91.0 2E8SE@1|root,33338@2|Bacteria,1NAYQ@1224|Proteobacteria,1SGKS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1648794_0 1384056.N787_08895 2.276e-168 558.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X372@135614|Xanthomonadales 135614|Xanthomonadales NU General secretion pathway protein xpsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N GDHHQS3_k127_1652614_6 314278.NB231_06001 3.13e-10 69.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SWXH@1236|Gammaproteobacteria,1X1CE@135613|Chromatiales 135613|Chromatiales S signal sequence binding - - - - - - - - - - - - - GDHHQS3_k127_1652614_4 1255043.TVNIR_3021 9.334e-33 137.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 GDHHQS3_k127_1652614_5 1034943.BN1094_01798 1.209e-13 74.0 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria,1JFAY@118969|Legionellales 118969|Legionellales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 GDHHQS3_k127_1652614_1 1123073.KB899241_gene2299 2.638e-134 432.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X3ZT@135614|Xanthomonadales 135614|Xanthomonadales C Heme copper-type cytochrome quinol oxidase subunit 3 cox3 - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 GDHHQS3_k127_1652614_3 1232683.ADIMK_2935 3.177e-42 162.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,466DV@72275|Alteromonadaceae 1236|Gammaproteobacteria O oxidase assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 GDHHQS3_k127_1652614_0 1469245.JFBG01000016_gene967 1.915e-282 875.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales 135613|Chromatiales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 GDHHQS3_k127_1652614_2 1469245.JFBG01000016_gene968 1.502e-127 419.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1WX49@135613|Chromatiales 135613|Chromatiales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 GDHHQS3_k127_1652614_7 1260251.SPISAL_01490 3.693e-09 64.0 COG5488@1|root,COG5488@2|Bacteria,1N9B7@1224|Proteobacteria,1SF1J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG5488 Integral membrane protein - - - - - - - - - - - - DUF2244 GDHHQS3_k127_1661995_6 1122137.AQXF01000001_gene2597 2.61e-20 96.0 COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U2RD@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase GDHHQS3_k127_1661995_1 1122137.AQXF01000001_gene2600 1.854e-141 458.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Zn-dependent dipeptidase, microsomal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 GDHHQS3_k127_1661995_3 313606.M23134_02374 1.628e-125 411.0 COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,47K7T@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 - - - MR_MLE_C,MR_MLE_N GDHHQS3_k127_1661995_4 1122137.AQXF01000001_gene2605 1.208e-99 337.0 COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria,2U6DV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane - - - - - - - - - - - - - GDHHQS3_k127_1661995_5 1472716.KBK24_0112920 2.586e-98 329.0 COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VH22@28216|Betaproteobacteria,1K4AS@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short,adh_short_C2 GDHHQS3_k127_1661995_2 1158292.JPOE01000002_gene2076 1.991e-134 437.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2VJ31@28216|Betaproteobacteria,1KKBT@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH GDHHQS3_k127_1661995_0 596153.Alide_2901 5.828e-212 669.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VI1V@28216|Betaproteobacteria,4ABKZ@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_1686314_2 96561.Dole_2010 2.01e-13 70.0 COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,42MKC@68525|delta/epsilon subdivisions,2WK3U@28221|Deltaproteobacteria,2MI82@213118|Desulfobacterales 28221|Deltaproteobacteria IQ AMP-binding enzyme - - 6.1.3.1 ko:K22319 - - - - ko00000,ko01000 - - - AMP-binding GDHHQS3_k127_1686314_0 566466.NOR53_858 2.438e-106 355.0 COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,1RQ2R@1236|Gammaproteobacteria,1JA8Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M NAD(P)H-binding cdh1 - 1.1.1.412 ko:K22320 - - - - ko00000,ko01000 - - - 3Beta_HSD GDHHQS3_k127_1686314_1 1030157.AFMP01000040_gene1562 8.668e-82 285.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2TRYX@28211|Alphaproteobacteria,2K204@204457|Sphingomonadales 204457|Sphingomonadales S membrane transporter protein - - - - - - - - - - - - TauE GDHHQS3_k127_1696013_0 639282.DEFDS_1472 2.082e-103 347.0 COG2230@1|root,COG2230@2|Bacteria,2GENQ@200930|Deferribacteres 200930|Deferribacteres H Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS GDHHQS3_k127_1696013_1 1232683.ADIMK_3622 1.856e-94 327.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,4645M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Reductase C-terminal alkT - 1.18.1.1,1.18.1.3 ko:K00529,ko:K21738 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C GDHHQS3_k127_1696013_2 1336243.JAEA01000001_gene1971 8.17e-14 73.0 COG0633@1|root,COG0633@2|Bacteria,1N261@1224|Proteobacteria,2UC7B@28211|Alphaproteobacteria,1JYE9@119045|Methylobacteriaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain fdx - - ko:K04755 - - - - ko00000 - - - Fer2 GDHHQS3_k127_1742753_2 349124.Hhal_2265 2.651e-34 139.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1WZ5M@135613|Chromatiales 135613|Chromatiales K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components rfaH - - ko:K05785 - - - - ko00000,ko03000 - - - NusG GDHHQS3_k127_1742753_3 1123228.AUIH01000084_gene360 3.813e-31 133.0 COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,1XMBR@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_24 GDHHQS3_k127_1742753_0 1116472.MGMO_115c00180 3.24e-195 621.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XEJF@135618|Methylococcales 135618|Methylococcales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GDHHQS3_k127_1742753_1 765913.ThidrDRAFT_2196 3.387e-137 444.0 COG1089@1|root,COG1089@2|Bacteria,1R9QJ@1224|Proteobacteria,1S1QW@1236|Gammaproteobacteria,1WVZK@135613|Chromatiales 135613|Chromatiales M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - - - - - - - - - - GDP_Man_Dehyd GDHHQS3_k127_1757240_2 886293.Sinac_5166 8.711e-12 66.0 COG0451@1|root,COG0451@2|Bacteria,2IZ0M@203682|Planctomycetes 203682|Planctomycetes GM Polysaccharide biosynthesis protein - - 1.1.1.203 ko:K18981 ko00053,map00053 - R10841 RC00066 ko00000,ko00001,ko01000 - - - Epimerase GDHHQS3_k127_1757240_1 595537.Varpa_5075 3.59e-47 172.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2VSZQ@28216|Betaproteobacteria,4AEKY@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1428) ybaA - - - - - - - - - - - DUF1428 GDHHQS3_k127_1757240_0 153948.NAL212_1474 3.214e-230 725.0 COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2VTVG@28216|Betaproteobacteria,3723C@32003|Nitrosomonadales 28216|Betaproteobacteria EGP Transmembrane secretion effector - - - ko:K08225 - - - - ko00000,ko02000 2.A.1.38 - - MFS_3 GDHHQS3_k127_1781388_3 631362.Thi970DRAFT_03892 1.779e-37 149.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1WYPZ@135613|Chromatiales 135613|Chromatiales P PFAM Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P GDHHQS3_k127_1781388_2 247634.GPB2148_780 2.489e-42 162.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU GDHHQS3_k127_1781388_1 1535422.ND16A_2476 1.807e-46 172.0 COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S7IY@1236|Gammaproteobacteria,2Q76T@267889|Colwelliaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_1781388_4 398527.Bphyt_6800 9.293e-36 141.0 COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2VTIJ@28216|Betaproteobacteria,1K7KT@119060|Burkholderiaceae 28216|Betaproteobacteria T TspO/MBR family - - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR GDHHQS3_k127_1781388_0 1301098.PKB_1498 1.097e-137 451.0 COG0160@1|root,COG0160@2|Bacteria,1MX0Y@1224|Proteobacteria,1RQ9Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 GDHHQS3_k127_1781388_5 1123229.AUBC01000007_gene162 6.911e-17 84.0 COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,2U31H@28211|Alphaproteobacteria,3JZZG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH GDHHQS3_k127_1797034_0 1163617.SCD_n02069 1.327e-146 474.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria 28216|Betaproteobacteria J SMART PUA domain containing protein rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM GDHHQS3_k127_1797034_1 1280001.BAOA01000112_gene4648 1.471e-146 470.0 COG3274@1|root,COG3274@2|Bacteria,1MUJ6@1224|Proteobacteria,1S09B@1236|Gammaproteobacteria,1XT5S@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - Acyl_transf_3 GDHHQS3_k127_1797034_2 926550.CLDAP_16780 5.218e-115 377.0 COG5598@1|root,COG5598@2|Bacteria 2|Bacteria H trimethylamine methyltransferase - - 2.1.1.250 ko:K14083 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00563 R09124,R10016 RC00035,RC00732,RC01144,RC02984 ko00000,ko00001,ko00002,ko01000 - - - MTTB GDHHQS3_k127_1823109_2 1419583.V466_17860 9.549e-05 48.0 2DQB8@1|root,335RW@2|Bacteria,1NGS1@1224|Proteobacteria,1SHJ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1823109_0 1122603.ATVI01000004_gene1823 9.044e-216 678.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1XCGK@135614|Xanthomonadales 135614|Xanthomonadales L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DUF772 GDHHQS3_k127_1823109_1 330214.NIDE4316 4.381e-30 121.0 COG0389@1|root,COG0389@2|Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH GDHHQS3_k127_182885_1 1123401.JHYQ01000006_gene73 7.851e-36 136.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales 72273|Thiotrichales F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS GDHHQS3_k127_182885_0 1123399.AQVE01000011_gene1234 2.595e-161 521.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales 72273|Thiotrichales F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase GDHHQS3_k127_182885_2 622637.KE124774_gene897 3.76e-21 96.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,36X96@31993|Methylocystaceae 28211|Alphaproteobacteria E Dihydrodipicolinate reductase, C-terminus dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N GDHHQS3_k127_1841872_3 375286.mma_0505 1.782e-67 244.0 COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VKME@28216|Betaproteobacteria,475SC@75682|Oxalobacteraceae 28216|Betaproteobacteria O XdhC Rossmann domain xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI GDHHQS3_k127_1841872_0 394221.Mmar10_1236 4.643e-135 439.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria,43WCV@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase GDHHQS3_k127_1841872_1 930169.B5T_03916 2.125e-124 413.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XIB8@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - Urate_ox_N GDHHQS3_k127_1841872_5 1123377.AUIV01000022_gene1992 2.274e-42 160.0 COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1X6FA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoaC GDHHQS3_k127_1841872_4 1307834.BARL01000002_gene1264 2.716e-49 181.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2UV0F@28211|Alphaproteobacteria 28211|Alphaproteobacteria H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE GDHHQS3_k127_1841872_9 1123070.KB899249_gene327 2.734e-10 64.0 COG0746@1|root,COG1977@1|root,COG0746@2|Bacteria,COG1977@2|Bacteria,46WDY@74201|Verrucomicrobia,2IUZR@203494|Verrucomicrobiae 203494|Verrucomicrobiae H MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 GDHHQS3_k127_1841872_2 767434.Fraau_1806 1.453e-104 351.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM GDHHQS3_k127_1841872_8 247634.GPB2148_1379 1.468e-19 91.0 2EEXN@1|root,338R0@2|Bacteria,1N90Z@1224|Proteobacteria,1SF03@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF3144 GDHHQS3_k127_1841872_7 1123073.KB899241_gene2464 3.979e-26 124.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - AXE1,Peptidase_S9 GDHHQS3_k127_1874978_1 1121013.P873_06190 1.273e-69 246.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,1RZ6C@1236|Gammaproteobacteria,1X6QA@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_1874978_0 1121015.N789_02440 2.352e-93 315.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,1X4VY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF455 GDHHQS3_k127_190612_6 1122137.AQXF01000001_gene3108 4.743e-12 74.0 COG2220@1|root,COG2220@2|Bacteria,1RKSI@1224|Proteobacteria,2UNK6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 GDHHQS3_k127_190612_4 264462.Bd0784 3.76e-27 122.0 2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,42W26@68525|delta/epsilon subdivisions,2MU2D@213481|Bdellovibrionales,2WSHN@28221|Deltaproteobacteria 213481|Bdellovibrionales - - - - - - - - - - - - - - - GDHHQS3_k127_190612_3 583355.Caka_1410 8.651e-28 123.0 28IAE@1|root,2Z8D0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_190612_1 523791.Kkor_1560 1.272e-80 278.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,1SF7R@1236|Gammaproteobacteria,1XQY1@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA GDHHQS3_k127_190612_7 2340.JV46_23390 4.023e-11 73.0 COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S4VY@1236|Gammaproteobacteria,1JAMV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D sister chromatid segregation - - - - - - - - - - - - - GDHHQS3_k127_190612_2 941449.dsx2_0385 1.638e-66 242.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,2MAD8@213115|Desulfovibrionales 28221|Deltaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC GDHHQS3_k127_190612_0 1234364.AMSF01000016_gene1713 5.858e-128 433.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales 135614|Xanthomonadales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase GDHHQS3_k127_190612_5 1036674.A28LD_0015 1.974e-17 86.0 28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,1RY8I@1236|Gammaproteobacteria,2QGGD@267893|Idiomarinaceae 1236|Gammaproteobacteria S S1/P1 Nuclease - - 3.1.30.1 ko:K05986 - - - - ko00000,ko01000 - - - S1-P1_nuclease GDHHQS3_k127_191680_3 493475.GARC_1156 2.84e-27 116.0 COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,1SBVZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG GDHHQS3_k127_191680_1 1121935.AQXX01000106_gene572 2.385e-55 203.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XJA6@135619|Oceanospirillales 135619|Oceanospirillales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB GDHHQS3_k127_191680_0 572477.Alvin_2538 6.412e-112 380.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales 135613|Chromatiales F SAICAR synthetase purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt GDHHQS3_k127_191680_2 911045.PSE_1610 1.552e-48 180.0 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,2UHWY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 GDHHQS3_k127_191680_4 1449069.JMLO01000018_gene588 3.294e-08 65.0 COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae 201174|Actinobacteria C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Copper-bind,Cupredoxin_1 GDHHQS3_k127_1927422_2 1385517.N800_08795 5.398e-91 310.0 COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,1RYUQ@1236|Gammaproteobacteria,1X5KG@135614|Xanthomonadales 135614|Xanthomonadales S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - GDHHQS3_k127_1927422_4 1268068.PG5_00220 3.111e-22 102.0 COG3544@1|root,COG3544@2|Bacteria 2|Bacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 GDHHQS3_k127_1927422_3 1209072.ALBT01000011_gene3253 1.618e-50 183.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1FFYK@10|Cellvibrio 1236|Gammaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K22348 - - - - ko00000,ko01000 - - - Cu-oxidase_2,Cu-oxidase_3 GDHHQS3_k127_1927422_0 1163617.SCD_n01997 4.914e-151 484.0 COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria 28216|Betaproteobacteria P membrane protein, terc ygjT - - ko:K05794 - - - - ko00000 - - - TerC GDHHQS3_k127_1927422_1 1237149.C900_02493 2.317e-134 438.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 GDHHQS3_k127_1934970_0 1121015.N789_09360 0.0 1254.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1X36U@135614|Xanthomonadales 135614|Xanthomonadales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg GDHHQS3_k127_1934970_1 1123073.KB899241_gene2322 5.749e-119 403.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1X4ZI@135614|Xanthomonadales 135614|Xanthomonadales U AAA domain - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 GDHHQS3_k127_1934970_6 1122603.ATVI01000007_gene1685 5.279e-05 54.0 2DRAW@1|root,33B0D@2|Bacteria,1QXFT@1224|Proteobacteria 1224|Proteobacteria S Type II secretion system protein B - - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB GDHHQS3_k127_1934970_4 1123073.KB899241_gene2324 1.237e-45 173.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1S510@1236|Gammaproteobacteria,1X48B@135614|Xanthomonadales 135614|Xanthomonadales S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid GDHHQS3_k127_1934970_5 1122185.N792_11825 1.526e-35 141.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1X6Z5@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF1820) - - - - - - - - - - - - DUF1820 GDHHQS3_k127_1934970_3 1123393.KB891316_gene1129 3.812e-59 211.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales 119069|Hydrogenophilales S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI GDHHQS3_k127_1934970_2 1177181.T9A_00741 3.349e-84 290.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XHC6@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 GDHHQS3_k127_1935788_1 767434.Fraau_0160 1.564e-58 205.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1X31P@135614|Xanthomonadales 135614|Xanthomonadales J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e GDHHQS3_k127_1935788_0 1234364.AMSF01000013_gene706 4.572e-179 584.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1X31Q@135614|Xanthomonadales 135614|Xanthomonadales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f GDHHQS3_k127_195955_0 1123392.AQWL01000003_gene290 2.529e-289 892.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales 119069|Hydrogenophilales C Inorganic H+ pyrophosphatase - - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase GDHHQS3_k127_195955_7 1192759.AKIB01000023_gene2962 7.841e-09 66.0 COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2UGEJ@28211|Alphaproteobacteria,2K33W@204457|Sphingomonadales 204457|Sphingomonadales O Prolyl 4-hydroxylase alpha subunit homologues. - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 GDHHQS3_k127_195955_2 1266908.AQPB01000061_gene1104 6.85e-204 659.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 GDHHQS3_k127_195955_6 713586.KB900536_gene2547 1.32e-37 148.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1WYFK@135613|Chromatiales 135613|Chromatiales CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin GDHHQS3_k127_195955_5 945713.IALB_2033 9.787e-46 172.0 COG3000@1|root,COG3000@2|Bacteria 2|Bacteria I iron ion binding - - - - - - - - - - - - FA_hydroxylase GDHHQS3_k127_195955_3 1288826.MSNKSG1_12182 1.188e-48 179.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,4671T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0560 DHquinase_II GDHHQS3_k127_195955_4 454957.IA64_20205 5.161e-48 176.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1X67R@135614|Xanthomonadales 135614|Xanthomonadales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl GDHHQS3_k127_195955_1 84531.JMTZ01000006_gene3458 2.392e-235 733.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1X43Q@135614|Xanthomonadales 135614|Xanthomonadales I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 GDHHQS3_k127_1964852_5 1265313.HRUBRA_00522 3.815e-50 184.0 COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 - R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 - - - NAD_binding_8 GDHHQS3_k127_1964852_4 1117647.M5M_17030 2.047e-63 228.0 COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria,1J5KT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 - R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 - - - NAD_binding_8 GDHHQS3_k127_1964852_3 1121374.KB891576_gene511 1.539e-78 272.0 28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_1964852_2 743721.Psesu_2076 2.532e-87 297.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,1RS51@1236|Gammaproteobacteria,1X58W@135614|Xanthomonadales 135614|Xanthomonadales S Glutamine - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 GDHHQS3_k127_1964852_0 382245.ASA_0173 1.237e-201 636.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1Y586@135624|Aeromonadales 135624|Aeromonadales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_1964852_1 1121374.KB891575_gene800 7.741e-91 310.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 GDHHQS3_k127_1981138_2 998674.ATTE01000001_gene1024 3.936e-31 122.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,46183@72273|Thiotrichales 72273|Thiotrichales K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GDHHQS3_k127_1981138_4 565045.NOR51B_2871 7.461e-13 79.0 COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,1S8WD@1236|Gammaproteobacteria,1JBSM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - - GDHHQS3_k127_1981138_0 935863.AWZR01000002_gene1023 2.19e-93 318.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1X4GY@135614|Xanthomonadales 135614|Xanthomonadales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran GDHHQS3_k127_1981138_3 1442599.JAAN01000005_gene892 2.289e-29 126.0 COG3165@1|root,COG3165@2|Bacteria,1N8UE@1224|Proteobacteria,1SE63@1236|Gammaproteobacteria,1X5YU@135614|Xanthomonadales 135614|Xanthomonadales S Sterol-binding protein - - - ko:K03690 - - - - ko00000 - - - SCP2 GDHHQS3_k127_1981138_1 1163409.UUA_12905 1.315e-37 145.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1X3E2@135614|Xanthomonadales 135614|Xanthomonadales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 GDHHQS3_k127_208172_3 1097668.BYI23_A003320 1.081e-37 143.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,1K3IP@119060|Burkholderiaceae 28216|Betaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase GDHHQS3_k127_208172_1 395493.BegalDRAFT_0253 7.852e-152 496.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4607S@72273|Thiotrichales 72273|Thiotrichales T nitrogen regulation protein NR(I) - - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat GDHHQS3_k127_208172_2 1500893.JQNB01000001_gene1074 9.437e-55 206.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1X3AZ@135614|Xanthomonadales 135614|Xanthomonadales T Signal transduction histidine kinase, nitrogen specific ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 GDHHQS3_k127_208172_0 697282.Mettu_3264 2.602e-239 746.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XEEH@135618|Methylococcales 135618|Methylococcales F TIGRFAM glutamine synthetase, type I - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N GDHHQS3_k127_2200620_5 1384056.N787_03045 3.639e-20 95.0 2C8T8@1|root,32RMU@2|Bacteria,1N089@1224|Proteobacteria,1SAT4@1236|Gammaproteobacteria,1X7F8@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_2200620_0 913325.N799_11785 3.305e-148 490.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1X31T@135614|Xanthomonadales 135614|Xanthomonadales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 GDHHQS3_k127_2200620_3 1267534.KB906760_gene1554 3.097e-29 120.0 2DD3Z@1|root,2ZGDH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_2200620_1 1267535.KB906767_gene2749 2.438e-110 363.0 COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria 57723|Acidobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 GDHHQS3_k127_2200620_4 671143.DAMO_2910 1.004e-23 109.0 2EHMT@1|root,33BDH@2|Bacteria 2|Bacteria S Alternative oxidase - - - - - - - - - - - - AOX GDHHQS3_k127_2200620_2 290398.Csal_0859 9.081e-70 244.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XH3U@135619|Oceanospirillales 135619|Oceanospirillales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA GDHHQS3_k127_2254812_0 1122137.AQXF01000006_gene896 1.006e-159 528.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_2254812_1 1282876.BAOK01000001_gene1753 3.15e-10 72.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria 1224|Proteobacteria M Protein involved in outer membrane biogenesis - - - ko:K07289,ko:K07290 - - - - ko00000 9.B.121 - - AsmA,AsmA_2 GDHHQS3_k127_225676_3 1122135.KB893137_gene1274 1.22e-91 306.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TTN3@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 GDHHQS3_k127_225676_1 1121935.AQXX01000140_gene1032 1.385e-118 388.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XH9S@135619|Oceanospirillales 135619|Oceanospirillales EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N GDHHQS3_k127_225676_2 1201293.AKXQ01000007_gene571 2.414e-115 381.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily oppD GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - iECED1_1282.ECED1_1398,iLF82_1304.LF82_1573,iSBO_1134.SBO_1821 ABC_tran,oligo_HPY GDHHQS3_k127_225676_0 414684.RC1_3368 1.452e-120 397.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPRD@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the ABC transporter superfamily - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY GDHHQS3_k127_225676_5 1357275.AVEL02000097_gene3412 7.27e-60 213.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB GDHHQS3_k127_225676_4 187272.Mlg_2878 1.717e-64 224.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GDHHQS3_k127_2269511_4 1121015.N789_06010 1.776e-40 154.0 COG4627@1|root,COG4627@2|Bacteria,1NKXY@1224|Proteobacteria 1224|Proteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 GDHHQS3_k127_2269511_3 1123073.KB899242_gene1542 1.301e-58 214.0 2ASS6@1|root,31I79@2|Bacteria,1QFWH@1224|Proteobacteria,1TD7B@1236|Gammaproteobacteria,1XA9E@135614|Xanthomonadales 135614|Xanthomonadales S Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 GDHHQS3_k127_2269511_5 472759.Nhal_3633 2.236e-17 94.0 COG1560@1|root,COG1560@2|Bacteria,1RJ7H@1224|Proteobacteria 1224|Proteobacteria M Kdo2-lipid A biosynthetic process - - - - - - - - - - - - Lip_A_acyltrans GDHHQS3_k127_2269511_2 634176.NT05HA_2330 1.147e-78 269.0 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1Y88W@135625|Pasteurellales 135625|Pasteurellales F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK GDHHQS3_k127_2269511_0 313606.M23134_05281 5.185e-116 385.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GDHHQS3_k127_2269511_1 870187.Thini_0934 3.039e-96 327.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,4602A@72273|Thiotrichales 72273|Thiotrichales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS GDHHQS3_k127_2273030_0 998088.B565_3821 1.978e-93 323.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1Y3N1@135624|Aeromonadales 135624|Aeromonadales S DNA recombination protein RmuC - - - ko:K09760 - - - - ko00000 - - - RmuC GDHHQS3_k127_2273030_3 1280952.HJA_17233 7.293e-38 148.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,43W7G@69657|Hyphomonadaceae 28211|Alphaproteobacteria S MazG family mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG GDHHQS3_k127_2273030_1 84531.JMTZ01000044_gene979 8.074e-87 304.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1X4YX@135614|Xanthomonadales 135614|Xanthomonadales T Signal transduction histidine kinase - - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c GDHHQS3_k127_2273030_2 1283300.ATXB01000002_gene3008 3.578e-43 160.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XDXZ@135618|Methylococcales 135618|Methylococcales K Response regulator receiver - - - - - - - - - - - - Response_reg,Trans_reg_C GDHHQS3_k127_2275299_0 1040982.AXAL01000027_gene3149 6.237e-148 478.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,43J3F@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO GDHHQS3_k127_2275299_2 1123319.AUBE01000005_gene202 1.147e-32 130.0 COG4311@1|root,COG4311@2|Bacteria,2IQIZ@201174|Actinobacteria 201174|Actinobacteria E Sarcosine oxidase soxD - 1.5.3.1 ko:K00304 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxD GDHHQS3_k127_2275299_1 1207063.P24_08594 1.392e-68 237.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2JQIX@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the GcvT family - - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 GDHHQS3_k127_2281924_3 519989.ECTPHS_12617 6.844e-13 68.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d GDHHQS3_k127_2281924_2 713586.KB900536_gene2406 7.288e-23 105.0 COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR GDHHQS3_k127_2281924_0 1123073.KB899241_gene2012 1.788e-66 248.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1X3AP@135614|Xanthomonadales 135614|Xanthomonadales S Oxygen tolerance - - - - - - - - - - - - BatD GDHHQS3_k127_2281924_1 1479237.JMLY01000001_gene2865 1.343e-32 134.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 GDHHQS3_k127_2287533_4 765910.MARPU_03615 1.044e-34 135.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1WWEP@135613|Chromatiales 135613|Chromatiales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro GDHHQS3_k127_2287533_3 1121013.P873_03875 7.273e-65 229.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1X34R@135614|Xanthomonadales 135614|Xanthomonadales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C GDHHQS3_k127_2287533_0 572477.Alvin_2382 1.989e-149 477.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales 135613|Chromatiales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N GDHHQS3_k127_2287533_6 1046724.KB889908_gene927 7.943e-06 48.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,464JX@72275|Alteromonadaceae 1236|Gammaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Pribosyl_synth,Pribosyltran_N GDHHQS3_k127_2287533_2 550540.Fbal_2828 1.95e-74 260.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N GDHHQS3_k127_2287533_5 935567.JAES01000051_gene322 7.021e-31 129.0 COG3017@1|root,COG3017@2|Bacteria,1PW07@1224|Proteobacteria,1RVWS@1236|Gammaproteobacteria,1X72U@135614|Xanthomonadales 135614|Xanthomonadales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB GDHHQS3_k127_2287533_1 323261.Noc_0511 1.347e-75 276.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 GDHHQS3_k127_2297513_1 85643.Tmz1t_2955 7.645e-55 196.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,2KY1I@206389|Rhodocyclales 206389|Rhodocyclales C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N GDHHQS3_k127_2297513_0 85643.Tmz1t_2956 7.459e-129 417.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,2KY5Y@206389|Rhodocyclales 206389|Rhodocyclales C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C GDHHQS3_k127_2297513_2 316055.RPE_0600 3.714e-42 162.0 COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Rubrerythrin - - - - - - - - - - - - Rubrerythrin GDHHQS3_k127_2297513_3 1528106.JRJE01000003_gene811 3.468e-38 147.0 COG1959@1|root,COG1959@2|Bacteria,1PZ79@1224|Proteobacteria,2UCUA@28211|Alphaproteobacteria,2JTF5@204441|Rhodospirillales 204441|Rhodospirillales K transcriptional regulator - - - - - - - - - - - - Rrf2 GDHHQS3_k127_2303989_4 1384056.N787_12885 2.321e-71 246.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S2NX@1236|Gammaproteobacteria,1XCVM@135614|Xanthomonadales 135614|Xanthomonadales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - - - - - - - - - - Pro_isomerase GDHHQS3_k127_2303989_2 1123073.KB899242_gene1599 1.948e-108 367.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1X37K@135614|Xanthomonadales 135614|Xanthomonadales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_2303989_1 1123073.KB899242_gene1600 8.888e-121 402.0 COG1365@1|root,COG1365@2|Bacteria,1R62V@1224|Proteobacteria,1S2JY@1236|Gammaproteobacteria,1X5D9@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_2303989_3 1442599.JAAN01000030_gene2115 2.911e-94 327.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,1MUA6@1224|Proteobacteria,1SZXB@1236|Gammaproteobacteria,1X4T0@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family lysA - 2.7.2.4,4.1.1.20 ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC GDHHQS3_k127_2303989_0 1384054.N790_12115 1.308e-281 880.0 COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1X4EX@135614|Xanthomonadales 135614|Xanthomonadales J elongation factor G - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU GDHHQS3_k127_2304930_0 396588.Tgr7_2895 4.195e-242 754.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1WVY5@135613|Chromatiales 135613|Chromatiales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD GDHHQS3_k127_2304930_1 1031711.RSPO_c03266 1.248e-107 356.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,1K09X@119060|Burkholderiaceae 28216|Betaproteobacteria E Methylenetetrahydrofolate reductase metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR GDHHQS3_k127_2304930_2 1268239.PALB_32680 5.858e-94 314.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,2Q19T@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG1446 Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 GDHHQS3_k127_2310783_10 1185876.BN8_05409 5.782e-12 73.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin GDHHQS3_k127_2310783_2 1323663.AROI01000006_gene2908 1.482e-87 304.0 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp GDHHQS3_k127_2310783_0 1384054.N790_02840 1.051e-308 961.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Nitrite reductase nirS - 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 GDHHQS3_k127_2310783_1 713586.KB900536_gene3092 5.763e-141 475.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1WWEW@135613|Chromatiales 135613|Chromatiales P TonB-dependent heme hemoglobin receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec GDHHQS3_k127_2310783_4 1166948.JPZL01000003_gene752 5.533e-42 158.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,1XJZ2@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator - - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 GDHHQS3_k127_2310783_7 261292.Nit79A3_2142 5.065e-22 103.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,373C5@32003|Nitrosomonadales 28216|Betaproteobacteria S PFAM Invasion gene expression up-regulator, SirB sirB - - - - - - - - - - - SirB GDHHQS3_k127_2310783_3 1121937.AUHJ01000010_gene1681 3.927e-69 245.0 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,1T3KJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 GDHHQS3_k127_2310783_8 1120972.AUMH01000004_gene1526 1.011e-15 79.0 COG3565@1|root,COG3565@2|Bacteria,1V6AX@1239|Firmicutes,4HIET@91061|Bacilli 91061|Bacilli S glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06991 - - - - ko00000 - - - Glyoxalase GDHHQS3_k127_2310783_5 1045855.DSC_05585 5.208e-33 128.0 COG3514@1|root,COG3514@2|Bacteria,1NAV1@1224|Proteobacteria,1SC0H@1236|Gammaproteobacteria,1XBA7@135614|Xanthomonadales 135614|Xanthomonadales S CopG antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin GDHHQS3_k127_2310783_6 1123401.JHYQ01000001_gene1824 2.06e-31 124.0 COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,463D1@72273|Thiotrichales 72273|Thiotrichales S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - ko:K09803 - - - - ko00000 - - - BrnT_toxin GDHHQS3_k127_2310783_9 1158146.KB907125_gene2405 2.491e-14 74.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria,1WXG0@135613|Chromatiales 135613|Chromatiales V Type II restriction enzyme, methylase - - - - - - - - - - - - - GDHHQS3_k127_2327680_3 1026882.MAMP_01739 2.43e-158 506.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N GDHHQS3_k127_2327680_0 247633.GP2143_05430 1.867e-202 644.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1J506@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB GDHHQS3_k127_2327680_2 1049564.TevJSym_aa01800 2.222e-182 581.0 COG1055@1|root,COG1055@2|Bacteria 2|Bacteria P arsenite transmembrane transporter activity - - - - - - - - - - - - CitMHS GDHHQS3_k127_2327680_6 1122951.ATUE01000006_gene1424 9.914e-65 224.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,3NN4K@468|Moraxellaceae 1236|Gammaproteobacteria E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase GDHHQS3_k127_2327680_9 1282876.BAOK01000001_gene1175 1.313e-24 108.0 COG3409@1|root,COG3409@2|Bacteria,1NP3I@1224|Proteobacteria,2UM8V@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - GDHHQS3_k127_2327680_7 639282.DEFDS_1443 2.865e-36 143.0 COG2905@1|root,COG2905@2|Bacteria,2GGGX@200930|Deferribacteres 200930|Deferribacteres T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS GDHHQS3_k127_2327680_8 913325.N799_08065 1.803e-27 115.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,1X8CT@135614|Xanthomonadales 135614|Xanthomonadales P ferredoxin - - - - - - - - - - - - Rieske GDHHQS3_k127_2327680_1 1469245.JFBG01000054_gene2119 5.603e-197 632.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXQ0@135613|Chromatiales 135613|Chromatiales P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C GDHHQS3_k127_2327680_5 568768.CM001975_gene880 1.184e-82 282.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,2JDPC@204037|Dickeya 1236|Gammaproteobacteria H Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 GDHHQS3_k127_2327680_4 396588.Tgr7_3236 7.527e-97 319.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales 135613|Chromatiales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG GDHHQS3_k127_2332897_6 1255043.TVNIR_0794 4.18e-30 121.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG GDHHQS3_k127_2332897_3 1120960.ATXG01000006_gene2234 9.408e-110 388.0 COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria 201174|Actinobacteria C Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos GDHHQS3_k127_2332897_2 1122137.AQXF01000001_gene3211 8.626e-113 379.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,2TSKZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE GDHHQS3_k127_2332897_7 715226.ABI_30290 8.086e-23 109.0 290BZ@1|root,2ZN1G@2|Bacteria,1R9MB@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2608) - - - - - - - - - - - - DUF2608 GDHHQS3_k127_2332897_8 194867.ALBQ01000011_gene384 4.765e-06 50.0 COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales 204457|Sphingomonadales H receptor - - - - - - - - - - - - Plug GDHHQS3_k127_2332897_0 622637.KE124774_gene690 1.084e-219 705.0 COG3119@1|root,COG3119@2|Bacteria,1R7JF@1224|Proteobacteria,2UHTB@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Sulfatase - - - - - - - - - - - - Sulfatase GDHHQS3_k127_2332897_9 1185652.USDA257_c22330 9.527e-05 48.0 COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,2U73E@28211|Alphaproteobacteria,4BMWB@82115|Rhizobiaceae 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN GDHHQS3_k127_2332897_5 1122603.ATVI01000009_gene2697 1.745e-39 148.0 COG4691@1|root,COG4691@2|Bacteria,1N8BI@1224|Proteobacteria,1SDUR@1236|Gammaproteobacteria,1X8G9@135614|Xanthomonadales 135614|Xanthomonadales S Plasmid stability protein - - - ko:K21495 - - - - ko00000,ko02048 - - - Arc GDHHQS3_k127_2332897_4 1122603.ATVI01000009_gene2698 1.391e-66 228.0 COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,1SAJG@1236|Gammaproteobacteria,1X758@135614|Xanthomonadales 135614|Xanthomonadales S Toxic component of a toxin-antitoxin (TA) module. An RNase vapC - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN GDHHQS3_k127_2332897_1 565045.NOR51B_513 4.806e-133 453.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1J4UG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_2338190_16 519989.ECTPHS_00685 1.69e-13 74.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 GDHHQS3_k127_2338190_12 84531.JMTZ01000083_gene4300 4.861e-52 190.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1X5ZP@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterized protein family UPF0029 - - - - - - - - - - - - DUF1949,UPF0029 GDHHQS3_k127_2338190_0 1121405.dsmv_1458 8.212e-293 906.0 COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria,42P34@68525|delta/epsilon subdivisions,2WK9S@28221|Deltaproteobacteria,2MI0B@213118|Desulfobacterales 28221|Deltaproteobacteria I Carboxyl transferase domain gcdA - 4.1.1.70 ko:K01615 ko00362,ko00650,ko01120,map00362,map00650,map01120 - R03028 RC00832 ko00000,ko00001,ko01000,ko02000 3.B.1.1.3 - - Carboxyl_trans GDHHQS3_k127_2338190_3 879212.DespoDRAFT_00645 3.159e-167 532.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MI33@213118|Desulfobacterales 28221|Deltaproteobacteria C Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta GDHHQS3_k127_2338190_15 1121405.dsmv_2550 1.283e-17 87.0 COG4770@1|root,COG4770@2|Bacteria,1NCKN@1224|Proteobacteria,42W8Y@68525|delta/epsilon subdivisions,2WRW7@28221|Deltaproteobacteria,2MM43@213118|Desulfobacterales 28221|Deltaproteobacteria I Biotin-requiring enzyme - - - - - - - - - - - - Biotin_lipoyl GDHHQS3_k127_2338190_2 1125863.JAFN01000001_gene3100 1.203e-175 557.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM Acyl-CoA dehydrogenase - - 1.3.99.32 ko:K16173 ko00362,ko01120,map00362,map01120 - R05579 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_2338190_5 1384056.N787_02570 2.403e-127 419.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,1X4TS@135614|Xanthomonadales 135614|Xanthomonadales S Saccharopine dehydrogenase NADP binding domain - - - - - - - - - - - - Sacchrp_dh_NADP GDHHQS3_k127_2338190_10 1033802.SSPSH_000452 1.569e-67 240.0 COG0300@1|root,COG0300@2|Bacteria,1QU6Z@1224|Proteobacteria,1T1P9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short GDHHQS3_k127_2338190_14 118005.AWNK01000003_gene2249 1.966e-22 103.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_24,MarR_2 GDHHQS3_k127_2338190_1 1385517.N800_05265 7.57e-285 889.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1X445@135614|Xanthomonadales 135614|Xanthomonadales C 2,4-dienoyl-coa reductase fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 GDHHQS3_k127_2338190_7 1442599.JAAN01000031_gene1411 5.217e-76 262.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1X3NA@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine deoD - 2.4.2.44 ko:K19696 ko00270,ko01100,map00270,map01100 - R09668 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 GDHHQS3_k127_2338190_13 1415780.JPOG01000001_gene1518 1.438e-39 153.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1X3NG@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran GDHHQS3_k127_2338190_6 349124.Hhal_1261 1.598e-88 303.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales 135613|Chromatiales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 GDHHQS3_k127_2338190_4 1384054.N790_10935 1.009e-159 514.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr GDHHQS3_k127_2338190_11 1121013.P873_12700 4.773e-55 199.0 COG3784@1|root,COG3784@2|Bacteria,1MYIH@1224|Proteobacteria,1S8D2@1236|Gammaproteobacteria,1X61X@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1318) - - - - - - - - - - - - DUF1318 GDHHQS3_k127_2338190_9 1384054.N790_10925 5.166e-73 273.0 COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,1S3FX@1236|Gammaproteobacteria,1X466@135614|Xanthomonadales 135614|Xanthomonadales S Protein conserved in bacteria - - - - - - - - - - - - - GDHHQS3_k127_2338190_17 68223.JNZY01000010_gene1840 7.759e-07 60.0 COG0745@1|root,COG0745@2|Bacteria,2GNFH@201174|Actinobacteria 201174|Actinobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain prrA GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944 - ko:K07671 ko02020,map02020 M00462 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GDHHQS3_k127_2338190_8 1231391.AMZF01000013_gene2623 4.251e-74 254.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,3T249@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ GDHHQS3_k127_2350474_5 690597.JH730961_gene4518 0.0008562 43.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1YP92@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD GDHHQS3_k127_2350474_3 1123377.AUIV01000010_gene2210 5.738e-45 169.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1X6GB@135614|Xanthomonadales 135614|Xanthomonadales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA GDHHQS3_k127_2350474_1 243365.CV_2208 2.046e-96 321.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KQB9@206351|Neisseriales 206351|Neisseriales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep GDHHQS3_k127_2350474_0 84531.JMTZ01000008_gene3333 1.883e-118 392.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1X349@135614|Xanthomonadales 135614|Xanthomonadales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB GDHHQS3_k127_2350474_2 1499686.BN1079_01487 4.08e-60 215.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII GDHHQS3_k127_2350474_4 935863.AWZR01000013_gene1530 1.878e-36 141.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,1X6EX@135614|Xanthomonadales 135614|Xanthomonadales CO Thioredoxin yneN - - - - - - - - - - - AhpC-TSA GDHHQS3_k127_2351005_3 247633.GP2143_03953 5.04e-11 63.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1J9Y8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - - - - - - - - - - - Fer2,Fer2_2 GDHHQS3_k127_2351005_0 493475.GARC_3526 6.414e-287 900.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 GDHHQS3_k127_2351005_1 1207063.P24_08439 2.684e-254 806.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JREA@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A GDHHQS3_k127_2351005_2 1207063.P24_08444 8.939e-88 295.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JV59@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B GDHHQS3_k127_2351423_2 1121013.P873_11895 2.322e-114 393.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,1X535@135614|Xanthomonadales 135614|Xanthomonadales I LssY C-terminus - - - - - - - - - - - - LssY_C,PAP2,SNARE_assoc GDHHQS3_k127_2351423_1 1234364.AMSF01000053_gene1285 9.434e-173 553.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1X4Y7@135614|Xanthomonadales 135614|Xanthomonadales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_2351423_5 765914.ThisiDRAFT_1753 1.039e-09 66.0 2952G@1|root,2ZSF9@2|Bacteria,1NFKJ@1224|Proteobacteria,1S5Q0@1236|Gammaproteobacteria,1WY9R@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - GDHHQS3_k127_2351423_4 383407.XOC_3699 4.09e-68 236.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1X668@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK GDHHQS3_k127_2351423_0 105559.Nwat_0242 5.469e-191 604.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK GDHHQS3_k127_2351423_3 1123392.AQWL01000003_gene290 1.623e-98 328.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales 119069|Hydrogenophilales C Inorganic H+ pyrophosphatase - - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase GDHHQS3_k127_2354892_2 392499.Swit_3254 5.385e-73 257.0 COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,2U257@28211|Alphaproteobacteria,2K2QA@204457|Sphingomonadales 204457|Sphingomonadales S Methylamine dehydrogenase heavy chain (MADH) - - 1.4.9.1 ko:K15229 ko00680,ko01120,map00680,map01120 - R00606 RC00189 ko00000,ko00001,ko01000 - - - Me-amine-dh_H GDHHQS3_k127_2354892_1 999141.GME_09194 5.231e-157 500.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RZGP@1236|Gammaproteobacteria,1XM4B@135619|Oceanospirillales 135619|Oceanospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_2354892_0 1118153.MOY_15483 1.178e-201 642.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1XKHY@135619|Oceanospirillales 135619|Oceanospirillales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 GDHHQS3_k127_2354892_6 411684.HPDFL43_21267 1.875e-14 78.0 2E3JP@1|root,32YI0@2|Bacteria,1N6ZI@1224|Proteobacteria,2UF5U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2783) - - - - - - - - - - - - DUF2783 GDHHQS3_k127_2354892_4 1049564.TevJSym_ai00380 3.434e-37 145.0 COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,1S89I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Hemerythrin HHE - - - - - - - - - - - - Hemerythrin GDHHQS3_k127_2354892_5 1123368.AUIS01000008_gene2154 1.375e-16 81.0 COG0425@1|root,COG0425@2|Bacteria,1QU8C@1224|Proteobacteria,1T5JF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249 GDHHQS3_k127_2354892_3 335283.Neut_0429 4.538e-44 161.0 COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,373DM@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative member of DMT superfamily (DUF486) - - - ko:K09922 - - - - ko00000 - - - DMT_6 GDHHQS3_k127_2380294_3 566466.NOR53_477 3.445e-112 389.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_2380294_1 314285.KT71_03017 6.18e-118 406.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_2380294_0 566466.NOR53_477 1.308e-119 411.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_2380294_2 566466.NOR53_3413 1.69e-114 396.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 GDHHQS3_k127_2380294_5 1415780.JPOG01000001_gene1950 3.705e-10 66.0 2DPMS@1|root,332PR@2|Bacteria,1N9MC@1224|Proteobacteria,1SEWG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2628) - - - - - - - - - - - - DUF2628 GDHHQS3_k127_2380294_4 247633.GP2143_10412 3.389e-40 151.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N GDHHQS3_k127_2383202_1 1384056.N787_01370 2.87e-121 398.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtB - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran GDHHQS3_k127_2383202_4 1121930.AQXG01000001_gene1204 3.654e-87 300.0 COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 GDHHQS3_k127_2383202_7 1384056.N787_01360 9.575e-32 127.0 COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,1SBJR@1236|Gammaproteobacteria,1X7P5@135614|Xanthomonadales 135614|Xanthomonadales C cytochrome - - - - - - - - - - - - Cytochrom_C GDHHQS3_k127_2383202_8 1469245.JFBG01000056_gene2461 2.749e-21 99.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales 135613|Chromatiales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 GDHHQS3_k127_2383202_5 1500890.JQNL01000001_gene3334 9.903e-66 231.0 COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1X4F3@135614|Xanthomonadales 135614|Xanthomonadales C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA - - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU GDHHQS3_k127_2383202_3 1122613.ATUP01000001_gene2020 5.952e-90 308.0 COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria,43Z22@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase GDHHQS3_k127_2383202_2 1384054.N790_00655 4.02e-109 362.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1X33Q@135614|Xanthomonadales 135614|Xanthomonadales M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase GDHHQS3_k127_2383202_0 1123073.KB899242_gene995 2.765e-216 692.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1X4MS@135614|Xanthomonadales 135614|Xanthomonadales GM Multidrug MFS transporter - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 GDHHQS3_k127_2383202_6 1118235.CAJH01000010_gene675 8.234e-32 133.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1X4RV@135614|Xanthomonadales 135614|Xanthomonadales M UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase rfb303 - - - - - - - - - - - Glycos_transf_4 GDHHQS3_k127_2384427_1 454957.IA64_04510 3.083e-22 100.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X30G@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 GDHHQS3_k127_2384427_0 545264.KB898755_gene2773 3.785e-149 486.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat GDHHQS3_k127_2389353_2 1232410.KI421415_gene3092 9.418e-124 411.0 COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase GDHHQS3_k127_2389353_7 765911.Thivi_2760 3.105e-32 132.0 COG2010@1|root,COG2010@2|Bacteria,1NDHN@1224|Proteobacteria,1S700@1236|Gammaproteobacteria,1WYGG@135613|Chromatiales 135613|Chromatiales C Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1 GDHHQS3_k127_2389353_4 472759.Nhal_1655 2.793e-95 323.0 COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria,1X27I@135613|Chromatiales 135613|Chromatiales C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 GDHHQS3_k127_2389353_1 1122194.AUHU01000004_gene1448 9.918e-148 494.0 COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB GDHHQS3_k127_2389353_0 1150626.PHAMO_570076 3.557e-251 786.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales 204441|Rhodospirillales C Fumarate reductase flavoprotein C-term - - - - - - - - - - - - FAD_binding_2,Succ_DH_flav_C GDHHQS3_k127_2389353_3 1238182.C882_4199 1.822e-97 325.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U3AH@28211|Alphaproteobacteria,2JRIM@204441|Rhodospirillales 204441|Rhodospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_3,Fer4_8 GDHHQS3_k127_2389353_10 1122212.AULO01000012_gene1062 4.053e-13 75.0 COG3029@1|root,COG3029@2|Bacteria,1MZ4C@1224|Proteobacteria,1SC0P@1236|Gammaproteobacteria,1XMN1@135619|Oceanospirillales 135619|Oceanospirillales C Fumarate reductase subunit C - - - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_C GDHHQS3_k127_2389353_9 1238182.C882_4201 9.465e-17 89.0 COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2UI14@28211|Alphaproteobacteria,2JUB3@204441|Rhodospirillales 204441|Rhodospirillales C Fumarate reductase subunit D - - - - - - - - - - - - Fumarate_red_D GDHHQS3_k127_2389353_6 156889.Mmc1_2223 8.548e-71 247.0 COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2U613@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Ubie_methyltran GDHHQS3_k127_2389353_8 1123322.KB904668_gene3754 5.06e-30 128.0 COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria 201174|Actinobacteria IQ Dehydrogenase bdhA - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 GDHHQS3_k127_2389353_5 1283300.ATXB01000001_gene1712 3.821e-76 261.0 COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,1T2D2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Dienelactone hydrolase family - - - ko:K07100 - - - - ko00000 - - - DLH GDHHQS3_k127_2389353_11 525309.HMPREF0494_0554 3.915e-07 55.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HCZ0@91061|Bacilli,3F3K6@33958|Lactobacillaceae 91061|Bacilli E amino acid potE2 - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GDHHQS3_k127_2403866_4 913325.N799_10455 8.235e-05 46.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1X4BP@135614|Xanthomonadales 135614|Xanthomonadales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran GDHHQS3_k127_2403866_2 686340.Metal_1017 3.211e-70 245.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1XE2F@135618|Methylococcales 135618|Methylococcales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB GDHHQS3_k127_2403866_1 1163409.UUA_04378 3.158e-92 311.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1X357@135614|Xanthomonadales 135614|Xanthomonadales O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm GDHHQS3_k127_2403866_3 243233.MCA0419 5.777e-44 166.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1XF78@135618|Methylococcales 135618|Methylococcales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE GDHHQS3_k127_2403866_0 935567.JAES01000004_gene114 5.616e-181 572.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1X4P1@135614|Xanthomonadales 135614|Xanthomonadales O Cytochrome C biogenesis ccmF2 - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm GDHHQS3_k127_2429865_5 1163407.UU7_12616 3.506e-27 120.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1X733@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 GDHHQS3_k127_2429865_0 870187.Thini_0837 4.873e-157 507.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales 72273|Thiotrichales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His GDHHQS3_k127_2429865_6 675817.VDA_002702 9.91e-25 116.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XSGH@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria rodZ - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 GDHHQS3_k127_2429865_4 1286106.MPL1_10677 2.484e-48 183.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,460N9@72273|Thiotrichales 72273|Thiotrichales NU TIGRFAM type IV pilus biogenesis stability protein PilW - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_2,TPR_8 GDHHQS3_k127_2429865_1 666685.R2APBS1_1776 6.699e-144 467.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1X39G@135614|Xanthomonadales 135614|Xanthomonadales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM GDHHQS3_k127_2429865_2 1442599.JAAN01000020_gene2571 1.115e-66 229.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1X62I@135614|Xanthomonadales 135614|Xanthomonadales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK GDHHQS3_k127_2429865_3 1266925.JHVX01000008_gene319 1.85e-50 186.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3724V@32003|Nitrosomonadales 28216|Betaproteobacteria I acyl-CoA dehydrogenase fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 GDHHQS3_k127_2432068_12 335284.Pcryo_2447 5.03e-19 89.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,3NIII@468|Moraxellaceae 1236|Gammaproteobacteria O Magnesium chelatase, subunit ChlI comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C GDHHQS3_k127_2432068_13 1211114.ALIP01000039_gene915 2.687e-17 83.0 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1X7UU@135614|Xanthomonadales 135614|Xanthomonadales S Membrane fusogenic activity - - - ko:K09806 - - - - ko00000 - - - BMFP GDHHQS3_k127_2432068_8 1479238.JQMZ01000001_gene1672 2.599e-50 181.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,43XWB@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnB GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II GDHHQS3_k127_2432068_5 1500890.JQNL01000001_gene2157 3.567e-80 277.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1X5NN@135614|Xanthomonadales 135614|Xanthomonadales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 GDHHQS3_k127_2432068_4 314285.KT71_03017 7.259e-82 299.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_2432068_0 2340.JV46_17210 4.312e-245 775.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1J4VK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge GDHHQS3_k127_2432068_9 765914.ThisiDRAFT_0458 3.964e-47 173.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales 135613|Chromatiales J PFAM Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP GDHHQS3_k127_2432068_1 1384056.N787_04280 2.184e-231 736.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X43I@135614|Xanthomonadales 135614|Xanthomonadales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS GDHHQS3_k127_2432068_11 1335757.SPICUR_01535 5.144e-24 104.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 GDHHQS3_k127_2432068_6 472759.Nhal_0755 1.541e-71 246.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1WY9P@135613|Chromatiales 135613|Chromatiales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin GDHHQS3_k127_2432068_3 1121013.P873_11400 3.011e-85 292.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1X4G5@135614|Xanthomonadales 135614|Xanthomonadales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N GDHHQS3_k127_2432068_2 754477.Q7C_1335 1.23e-111 365.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales 72273|Thiotrichales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C GDHHQS3_k127_2432068_7 435908.IDSA_10695 2.111e-68 238.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,2QG0M@267893|Idiomarinaceae 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like GDHHQS3_k127_2432068_10 296591.Bpro_1341 7.173e-38 144.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,4AAMV@80864|Comamonadaceae 28216|Betaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN2 - - - - - - - - - - - HemN_C,Radical_SAM GDHHQS3_k127_2432222_1 1163407.UU7_00812 6.75e-108 360.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1X2Y9@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD GDHHQS3_k127_2432222_2 187272.Mlg_1854 4.675e-18 91.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1WY1I@135613|Chromatiales 135613|Chromatiales M PFAM Outer membrane - - - ko:K06142 - - - - ko00000 - - - OmpH GDHHQS3_k127_2432222_0 1123073.KB899241_gene3367 6.005e-236 755.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales 135614|Xanthomonadales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA GDHHQS3_k127_244610_15 1177928.TH2_15207 9.363e-19 87.0 COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,2JRQF@204441|Rhodospirillales 204441|Rhodospirillales E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase GDHHQS3_k127_244610_0 682795.AciX8_0257 4.151e-229 731.0 COG3590@1|root,COG3590@2|Bacteria,3Y3CC@57723|Acidobacteria,2JIQB@204432|Acidobacteriia 204432|Acidobacteriia O Endothelin-converting enzyme - - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_244610_2 1122599.AUGR01000013_gene779 4.084e-138 459.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XI0W@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase class I and II - - 2.6.1.84,2.6.1.88 ko:K12252,ko:K14287 ko00330,ko01100,map00330,map01100 - R08197,R08618 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_244610_11 765911.Thivi_4526 1.314e-52 192.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1WXKD@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0502 family - - - ko:K09915 - - - - ko00000 - - - DUF480 GDHHQS3_k127_244610_9 1265503.KB905161_gene3478 1.206e-84 292.0 COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,1S2FJ@1236|Gammaproteobacteria,2Q6GX@267889|Colwelliaceae 1236|Gammaproteobacteria I Enoyl-CoA hydratase/isomerase phaB - - - - - - - - - - - ECH_1 GDHHQS3_k127_244610_1 1123399.AQVE01000032_gene788 1.827e-176 562.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,461NF@72273|Thiotrichales 72273|Thiotrichales E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 GDHHQS3_k127_244610_5 765952.PUV_00830 3.038e-115 380.0 COG0861@1|root,COG0861@2|Bacteria,2JGY6@204428|Chlamydiae 204428|Chlamydiae P Integral membrane protein TerC family - - - ko:K05794 - - - - ko00000 - - - TerC GDHHQS3_k127_244610_3 1380393.JHVP01000005_gene3588 1.161e-137 449.0 COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N GDHHQS3_k127_244610_12 1380393.JHVP01000005_gene3586 4.061e-44 172.0 COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria 201174|Actinobacteria E Belongs to the peptidase S51 family - - - - - - - - - - - - Peptidase_S51 GDHHQS3_k127_244610_6 1172188.KB911820_gene2095 1.251e-106 361.0 COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae 201174|Actinobacteria P Putative esterase - - - ko:K07214 - - - - ko00000 - - - DUF3327,Esterase GDHHQS3_k127_244610_4 649638.Trad_2691 1.209e-118 394.0 COG0189@1|root,COG0189@2|Bacteria 2|Bacteria HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - - GDHHQS3_k127_244610_8 710696.Intca_0099 4.279e-85 289.0 COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4FFF6@85021|Intrasporangiaceae 201174|Actinobacteria S Putative esterase - - - - - - - - - - - - Esterase GDHHQS3_k127_244610_13 1040989.AWZU01000025_gene6305 2.73e-27 121.0 COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 GDHHQS3_k127_244610_7 1120956.JHZK01000021_gene1586 3.692e-104 346.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,1JN5X@119043|Rhodobiaceae 28211|Alphaproteobacteria C Cytochrome c, mono- and diheme variants cycG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C GDHHQS3_k127_244610_14 631454.N177_2169 7.914e-20 98.0 COG3909@1|root,COG3909@2|Bacteria,1PT48@1224|Proteobacteria,2VBN6@28211|Alphaproteobacteria,1JPEM@119043|Rhodobiaceae 28211|Alphaproteobacteria C Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 GDHHQS3_k127_244610_10 344747.PM8797T_26070 1.795e-83 294.0 COG0076@1|root,COG0076@2|Bacteria 2|Bacteria E glutamate decarboxylase activity - - 4.1.1.86 ko:K13745 ko00260,ko01120,map00260,map01120 - R07650 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC GDHHQS3_k127_2463978_10 1121374.KB891589_gene74 1.736e-37 150.0 2E7KM@1|root,3322M@2|Bacteria,1N7XR@1224|Proteobacteria,1SQEB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_2463978_3 1121374.KB891589_gene75 8.994e-175 563.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_2463978_2 1123020.AUIE01000002_gene1406 2.775e-193 610.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria,1YFPY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase GDHHQS3_k127_2463978_7 392499.Swit_4807 1.31e-88 310.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,2K4V2@204457|Sphingomonadales 204457|Sphingomonadales C FAD binding domain - - - - - - - - - - - - FAD_binding_4 GDHHQS3_k127_2463978_12 318161.Sden_1464 7.303e-21 98.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,2QE2W@267890|Shewanellaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_2463978_5 596152.DesU5LDRAFT_0225 6.509e-122 402.0 COG1062@1|root,COG1062@2|Bacteria,1R15D@1224|Proteobacteria,43D6X@68525|delta/epsilon subdivisions,2X8DV@28221|Deltaproteobacteria,2MHGW@213115|Desulfovibrionales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N GDHHQS3_k127_2463978_4 1445613.JALM01000081_gene959 4.925e-171 542.0 COG0388@1|root,COG0388@2|Bacteria,2HW1E@201174|Actinobacteria,4EAGX@85010|Pseudonocardiales 201174|Actinobacteria S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase GDHHQS3_k127_2463978_1 1144672.F966_03290 1.427e-215 679.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,3NIKA@468|Moraxellaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family hcaB - 1.2.1.39,1.2.1.67 ko:K00146,ko:K21802 ko00360,ko00627,ko00643,ko01100,ko01120,map00360,map00627,map00643,map01100,map01120 - R02536,R05699 RC00075,RC00080 ko00000,ko00001,ko01000 - - - Aldedh GDHHQS3_k127_2463978_11 316067.Geob_0129 1.375e-23 108.0 COG3787@1|root,COG3787@2|Bacteria,1Q17Y@1224|Proteobacteria,42VKN@68525|delta/epsilon subdivisions,2WTH3@28221|Deltaproteobacteria,43V5G@69541|Desulfuromonadales 28221|Deltaproteobacteria S Pfam:Pyridox_oxidase - - - ko:K09979 - - - - ko00000 - - - Putative_PNPOx GDHHQS3_k127_2463978_8 1411685.U062_00561 1.438e-73 252.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1J5R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573 Flavoprotein GDHHQS3_k127_2463978_9 1122137.AQXF01000002_gene648 2.613e-38 160.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Zn-dependent dipeptidase, microsomal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 GDHHQS3_k127_2463978_6 392499.Swit_0918 6.095e-118 396.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2U1SE@28211|Alphaproteobacteria,2K2V3@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_2463978_0 1265310.CCBD010000014_gene3838 7.836e-218 686.0 COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae 201174|Actinobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD GDHHQS3_k127_2487161_6 1001585.MDS_0556 1.651e-16 82.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1YGR4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 GDHHQS3_k127_2487161_7 1123073.KB899241_gene2736 9.605e-15 77.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1X84C@135614|Xanthomonadales 135614|Xanthomonadales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 GDHHQS3_k127_2487161_3 768671.ThimaDRAFT_3082 3.508e-93 312.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC GDHHQS3_k127_2487161_9 1304883.KI912532_gene620 1.499e-10 71.0 COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,2KWHK@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - GDHHQS3_k127_2487161_5 234267.Acid_3894 4.352e-54 199.0 COG1611@1|root,COG1611@2|Bacteria,3Y4RU@57723|Acidobacteria 57723|Acidobacteria S Cytokinin riboside 5'-monophosphate phosphoribohydrolase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox GDHHQS3_k127_2487161_4 518766.Rmar_0276 2.59e-61 218.0 COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1FJ6W@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Eukaryotic integral membrane protein (DUF1751) - - 3.4.21.105 ko:K09650 - - - - ko00000,ko01000,ko01002,ko03029 - - - Rhomboid GDHHQS3_k127_2487161_1 85643.Tmz1t_1473 9.144e-174 572.0 COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales 206389|Rhodocyclales M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,Patatin GDHHQS3_k127_2487161_0 1282876.BAOK01000002_gene290 2.02e-310 962.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,4BP7M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C GDHHQS3_k127_2487161_8 991905.SL003B_3502 1.849e-14 77.0 COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2U9R9@28211|Alphaproteobacteria,4BSDQ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Lysin motif - - - - - - - - - - - - BON,LysM GDHHQS3_k127_2487161_2 1384056.N787_01985 4.788e-149 490.0 2DNHZ@1|root,32XM8@2|Bacteria,1QUVC@1224|Proteobacteria,1T3US@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_249535_5 675813.VIB_001743 5.997e-13 70.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XT77@135623|Vibrionales 135623|Vibrionales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB GDHHQS3_k127_249535_4 697282.Mettu_1399 3.133e-18 88.0 COG2921@1|root,COG2921@2|Bacteria,1PJDX@1224|Proteobacteria,1THTC@1236|Gammaproteobacteria,1XFN8@135618|Methylococcales 135618|Methylococcales S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 GDHHQS3_k127_249535_0 1026882.MAMP_00704 2.671e-128 422.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4602E@72273|Thiotrichales 72273|Thiotrichales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 GDHHQS3_k127_249535_3 1260251.SPISAL_07155 2.356e-62 223.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales 135613|Chromatiales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR GDHHQS3_k127_249535_2 377629.TERTU_0605 3.517e-87 299.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,2PN4W@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Transglycosylase SLT domain mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 GDHHQS3_k127_249535_1 1286106.MPL1_05409 1.316e-108 356.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,460BS@72273|Thiotrichales 72273|Thiotrichales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE GDHHQS3_k127_2513763_2 365046.Rta_27730 1.719e-05 46.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,4A9JV@80864|Comamonadaceae 28216|Betaproteobacteria M HlyD membrane-fusion protein of T1SS - - - ko:K02022,ko:K11003 ko03070,ko05133,map03070,map05133 M00325,M00575 - - ko00000,ko00001,ko00002,ko02000,ko02044 8.A.1.3.1,8.A.1.3.2 - - Biotin_lipoyl_2,HlyD,HlyD_3 GDHHQS3_k127_2513763_1 1227499.C493_19856 8.908e-102 347.0 COG1457@1|root,arCOG03447@2157|Archaea,2XW3K@28890|Euryarchaeota,23UB3@183963|Halobacteria 183963|Halobacteria F Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K10974 - - - - ko00000,ko02000 2.A.39.1 - - Transp_cyt_pur GDHHQS3_k127_2513763_0 1097668.BYI23_C004790 7.007e-216 677.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,1KFGH@119060|Burkholderiaceae 28216|Betaproteobacteria J Belongs to the amidase family - - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase GDHHQS3_k127_2528460_0 713586.KB900536_gene843 8.852e-132 432.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria 1236|Gammaproteobacteria I desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase GDHHQS3_k127_2528460_3 935863.AWZR01000001_gene1579 7.575e-108 355.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales 135614|Xanthomonadales V Transport permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane GDHHQS3_k127_2528460_1 1163407.UU7_06898 1.797e-129 421.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X31S@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 GDHHQS3_k127_2528460_2 251221.35210613 1.214e-115 390.0 COG0596@1|root,COG4188@1|root,COG0596@2|Bacteria,COG4188@2|Bacteria,1G7IV@1117|Cyanobacteria 1117|Cyanobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 GDHHQS3_k127_2528460_4 1384056.N787_11450 2.072e-98 332.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,1X307@135614|Xanthomonadales 135614|Xanthomonadales CP abc transporter atp-binding protein - - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran GDHHQS3_k127_2528460_5 1121015.N789_07665 6.644e-28 118.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1T04X@1236|Gammaproteobacteria,1XCYU@135614|Xanthomonadales 135614|Xanthomonadales CP Sodium ABC transporter permease - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 GDHHQS3_k127_2536752_2 1167006.UWK_01780 4.371e-20 95.0 2DMI9@1|root,32RQF@2|Bacteria,1NBF5@1224|Proteobacteria,42WJG@68525|delta/epsilon subdivisions,2WWMR@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core3 GDHHQS3_k127_2536752_0 309807.SRU_1660 8.773e-56 204.0 COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1FK1Q@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S DUF218 domain - - - - - - - - - - - - DUF218 GDHHQS3_k127_2536752_1 1415780.JPOG01000001_gene1595 1.006e-42 159.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1X738@135614|Xanthomonadales 135614|Xanthomonadales H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a GDHHQS3_k127_2536752_3 511.JT27_08625 7.45e-12 66.0 COG1522@1|root,COG1522@2|Bacteria,1N17E@1224|Proteobacteria,2VVKC@28216|Betaproteobacteria,3T3WJ@506|Alcaligenaceae 28216|Betaproteobacteria K transcriptional lrp_3 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type GDHHQS3_k127_2542897_1 1158150.KB906247_gene2316 1.749e-92 306.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1WWQP@135613|Chromatiales 135613|Chromatiales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B GDHHQS3_k127_2542897_3 1123073.KB899245_gene32 1.298e-73 253.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1X4TD@135614|Xanthomonadales 135614|Xanthomonadales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N GDHHQS3_k127_2542897_2 1500890.JQNL01000001_gene3056 3.604e-80 280.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X5AM@135614|Xanthomonadales 135614|Xanthomonadales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 GDHHQS3_k127_2542897_0 1279017.AQYJ01000024_gene1107 1.289e-107 349.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,465BP@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1525 DCD,dUTPase GDHHQS3_k127_2542897_4 754476.Q7A_1607 1.695e-62 218.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4606S@72273|Thiotrichales 72273|Thiotrichales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA GDHHQS3_k127_2559714_1 1408444.JHYC01000008_gene1427 1.861e-09 58.0 2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_2559714_0 472759.Nhal_0280 4.155e-15 87.0 COG2335@1|root,COG2335@2|Bacteria 2|Bacteria M COG2335, Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - CHRD,Fasciclin GDHHQS3_k127_2559714_2 864051.BurJ1DRAFT_0839 0.0009616 50.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2VR7A@28216|Betaproteobacteria,1KNN0@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP GDHHQS3_k127_2564105_2 767434.Fraau_2235 2.236e-109 362.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1X31G@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp GDHHQS3_k127_2564105_0 396588.Tgr7_2464 6.543e-145 469.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_2564105_5 314278.NB231_11974 3.432e-81 279.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1WWW9@135613|Chromatiales 135613|Chromatiales L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt - - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T GDHHQS3_k127_2564105_10 768671.ThimaDRAFT_4048 7.827e-35 145.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1WZGS@135613|Chromatiales 135613|Chromatiales S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB GDHHQS3_k127_2564105_9 1384056.N787_05285 3.981e-53 195.0 COG2259@1|root,COG2259@2|Bacteria,1RHIY@1224|Proteobacteria,1SIZV@1236|Gammaproteobacteria,1X7C9@135614|Xanthomonadales 135614|Xanthomonadales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX GDHHQS3_k127_2564105_6 768671.ThimaDRAFT_4544 4.416e-79 275.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1WXZ1@135613|Chromatiales 135613|Chromatiales S Putative DNA-binding domain - - - ko:K09929 - - - - ko00000 - - - DUF2063 GDHHQS3_k127_2564105_1 713586.KB900536_gene2708 7.963e-123 400.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1WWJ1@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 GDHHQS3_k127_2564105_11 1026882.MAMP_02002 4.148e-08 62.0 COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,461CR@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - GDHHQS3_k127_2564105_4 1121015.N789_05455 2.719e-96 319.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales 135614|Xanthomonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD GDHHQS3_k127_2564105_7 1198232.CYCME_0157 7.152e-73 255.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr GDHHQS3_k127_2564105_8 396588.Tgr7_2630 1.377e-55 201.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03612 - - - - ko00000 - - - FMN_bind GDHHQS3_k127_2564105_3 1121015.N789_05440 6.715e-103 338.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1X5Y0@135614|Xanthomonadales 135614|Xanthomonadales C Part of a membrane complex involved in electron transport - - - - - - - - - - - - NQR2_RnfD_RnfE GDHHQS3_k127_2568569_11 1122137.AQXF01000002_gene544 6.168e-66 236.0 COG4757@1|root,COG4757@2|Bacteria,1RI0P@1224|Proteobacteria 1224|Proteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 GDHHQS3_k127_2568569_15 1123368.AUIS01000003_gene1841 1.261e-24 108.0 COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 GDHHQS3_k127_2568569_3 2340.JV46_29040 1.026e-175 565.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH GDHHQS3_k127_2568569_2 187272.Mlg_2622 5.722e-190 603.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N GDHHQS3_k127_2568569_5 1123073.KB899241_gene2690 1.021e-137 452.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1X5SE@135614|Xanthomonadales 135614|Xanthomonadales T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat GDHHQS3_k127_2568569_6 187272.Mlg_2624 1.159e-133 456.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 GDHHQS3_k127_2568569_16 472759.Nhal_3819 1.383e-07 62.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 GDHHQS3_k127_2568569_8 1149133.ppKF707_5470 5.232e-111 374.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1YE4T@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB GDHHQS3_k127_2568569_7 767434.Fraau_3081 3.317e-111 369.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1X45U@135614|Xanthomonadales 135614|Xanthomonadales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N GDHHQS3_k127_2568569_12 1129374.AJE_09177 4.243e-57 203.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,466J1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GDHHQS3_k127_2568569_10 1163408.UU9_13513 9.729e-69 249.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1X3I7@135614|Xanthomonadales 135614|Xanthomonadales S peptidoglycan-binding protein, lysm - - - - - - - - - - - - LysM GDHHQS3_k127_2568569_9 1163407.UU7_12109 1.666e-107 360.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1X2Y5@135614|Xanthomonadales 135614|Xanthomonadales LU DNA processing protein DprA smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A GDHHQS3_k127_2568569_13 1384056.N787_09810 1.505e-54 195.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1X63Y@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 GDHHQS3_k127_2568569_1 187272.Mlg_2632 5.575e-296 929.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales 135613|Chromatiales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom GDHHQS3_k127_2568569_14 765914.ThisiDRAFT_1017 2.82e-48 181.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales 135613|Chromatiales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC GDHHQS3_k127_2568569_4 697282.Mettu_0781 6.994e-150 481.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XEKQ@135618|Methylococcales 135618|Methylococcales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas GDHHQS3_k127_2568569_0 396588.Tgr7_0087 0.0 1155.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales 135613|Chromatiales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 GDHHQS3_k127_2579203_5 686340.Metal_1713 4.176e-09 60.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1XEXS@135618|Methylococcales 135618|Methylococcales L Belongs to the DnaA family. HdA subfamily - - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA GDHHQS3_k127_2579203_1 697282.Mettu_1140 8.62e-98 332.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XEVN@135618|Methylococcales 135618|Methylococcales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport GDHHQS3_k127_2579203_3 472759.Nhal_0875 6.775e-45 169.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales 135613|Chromatiales I PFAM CDP-alcohol phosphatidyltransferase - - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf GDHHQS3_k127_2579203_4 105559.Nwat_1839 2.444e-27 124.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 GDHHQS3_k127_2579203_0 519989.ECTPHS_02936 3.104e-137 449.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1WWGF@135613|Chromatiales 135613|Chromatiales F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GDHHQS3_k127_2579203_2 1158182.KB905027_gene1559 1.41e-61 219.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1WY1C@135613|Chromatiales 135613|Chromatiales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N GDHHQS3_k127_2579203_6 1049564.TevJSym_af00870 7.568e-06 55.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T3YZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 GDHHQS3_k127_2608578_1 517722.AEUE01000001_gene2850 1.247e-95 318.0 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,2TXPM@28211|Alphaproteobacteria,2K1U8@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_2608578_3 1179773.BN6_46520 3.087e-76 268.0 COG2141@1|root,COG2141@2|Bacteria,2IEM9@201174|Actinobacteria 201174|Actinobacteria C Luciferase-like monooxygenase - - 1.5.98.2 ko:K00320 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R04464 RC01607 ko00000,ko00001,ko00002,ko01000 - - - Bac_luciferase GDHHQS3_k127_2608578_2 1123279.ATUS01000001_gene1689 1.883e-87 303.0 COG2807@1|root,COG2807@2|Bacteria,1QUSV@1224|Proteobacteria,1T3IC@1236|Gammaproteobacteria,1JC14@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_2608578_0 1123054.KB907730_gene2546 5.516e-141 460.0 COG1228@1|root,COG1228@2|Bacteria,1R2MB@1224|Proteobacteria,1T5T7@1236|Gammaproteobacteria,1X2W5@135613|Chromatiales 135613|Chromatiales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_2608578_5 381666.H16_B2446 7.204e-34 130.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VQCJ@28216|Betaproteobacteria,1K1CQ@119060|Burkholderiaceae 28216|Betaproteobacteria H Belongs to the UbiD family - - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD GDHHQS3_k127_262480_0 519989.ECTPHS_10341 3.352e-134 439.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N GDHHQS3_k127_262480_2 1469245.JFBG01000023_gene1283 3.089e-59 211.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales 135613|Chromatiales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf GDHHQS3_k127_262480_1 1163408.UU9_00455 9.526e-88 294.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1X491@135614|Xanthomonadales 135614|Xanthomonadales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE GDHHQS3_k127_2658137_2 998674.ATTE01000001_gene589 2.147e-96 333.0 COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 50S ribosome-binding GTPase - - - ko:K06883 - - - - ko00000 - - - DUF697,MMR_HSR1 GDHHQS3_k127_2658137_1 1123399.AQVE01000004_gene2538 2.792e-112 377.0 COG1100@1|root,COG1100@2|Bacteria,1R1W9@1224|Proteobacteria,1SK3H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF697) - - - - - - - - - - - - DUF697,MMR_HSR1 GDHHQS3_k127_2658137_4 1123377.AUIV01000024_gene144 1.096e-46 180.0 COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales 135614|Xanthomonadales S Putative adhesin - - - - - - - - - - - - DUF4097 GDHHQS3_k127_2658137_5 1384056.N787_04780 2.302e-05 54.0 2CKCT@1|root,32SC5@2|Bacteria,1N1BJ@1224|Proteobacteria,1T6U5@1236|Gammaproteobacteria,1X85I@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_2658137_3 1121015.N789_09510 2.062e-48 180.0 COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 GDHHQS3_k127_2658137_0 1121015.N789_09550 1.164e-317 992.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales 135614|Xanthomonadales I converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974 GDHHQS3_k127_266760_1 566466.NOR53_958 2.998e-91 307.0 COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,1RNFC@1236|Gammaproteobacteria,1J9ZS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ AMP-binding enzyme - - 6.1.3.1 ko:K22319 - - - - ko00000,ko01000 - - - AMP-binding GDHHQS3_k127_266760_0 566466.NOR53_726 4.044e-116 388.0 COG2267@1|root,COG2267@2|Bacteria,1QUW0@1224|Proteobacteria,1T231@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alpha beta hydrolase - - - ko:K22318 - - - - ko00000 - - - Abhydrolase_1 GDHHQS3_k127_266760_2 566466.NOR53_1454 2.366e-50 181.0 COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,1S3GP@1236|Gammaproteobacteria,1J7XP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - ko:K22317 - - - - ko00000 - - - ACP_syn_III,ACP_syn_III_C GDHHQS3_k127_267295_1 767434.Fraau_2757 1.891e-21 99.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1X41H@135614|Xanthomonadales 135614|Xanthomonadales S Pathogenicity protein - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB GDHHQS3_k127_267295_0 523791.Kkor_1776 2.323e-70 253.0 COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,1RXX1@1236|Gammaproteobacteria,1XQQE@135619|Oceanospirillales 135619|Oceanospirillales E Zn_pept - - - - - - - - - - - - Peptidase_M14,Peptidase_M6 GDHHQS3_k127_2701848_9 864051.BurJ1DRAFT_1892 7.249e-30 121.0 COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,2VVRD@28216|Betaproteobacteria,1KP3J@119065|unclassified Burkholderiales 28216|Betaproteobacteria S addiction module killer protein - - - - - - - - - - - - Gp49 GDHHQS3_k127_2701848_8 396588.Tgr7_1725 3.108e-39 149.0 COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,1SC8G@1236|Gammaproteobacteria,1WYIJ@135613|Chromatiales 135613|Chromatiales K addiction module antidote protein - - - - - - - - - - - - HTH_3 GDHHQS3_k127_2701848_13 1122604.JONR01000020_gene509 1.026e-08 57.0 COG3905@1|root,COG3905@2|Bacteria,1NBCD@1224|Proteobacteria,1SHTT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - - - - - - - - - - - GDHHQS3_k127_2701848_11 1122604.JONR01000020_gene508 3.927e-21 96.0 COG3668@1|root,COG3668@2|Bacteria,1N9C2@1224|Proteobacteria,1SHFW@1236|Gammaproteobacteria,1X8S9@135614|Xanthomonadales 135614|Xanthomonadales S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_2701848_2 493475.GARC_1691 2.348e-226 704.0 COG0388@1|root,COG0388@2|Bacteria,1RIJI@1224|Proteobacteria,1SA17@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase GDHHQS3_k127_2701848_0 493475.GARC_1690 1.031e-293 906.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1SBQZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Phytoene dehydrogenase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 GDHHQS3_k127_2701848_1 392499.Swit_1693 2.813e-231 719.0 COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TV84@28211|Alphaproteobacteria,2JZUU@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the mandelate racemase muconate lactonizing enzyme family - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704,GO:1901575 4.2.1.8 ko:K08323 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N GDHHQS3_k127_2701848_5 493475.GARC_1694 6.559e-103 360.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464J1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_2701848_3 493475.GARC_1695 1.781e-156 508.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh GDHHQS3_k127_2701848_12 1122221.JHVI01000003_gene382 6.315e-20 95.0 COG1846@1|root,COG1846@2|Bacteria,1WMZ0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR GDHHQS3_k127_2701848_7 1123059.KB823011_gene1808 5.966e-62 220.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,43XRN@69657|Hyphomonadaceae 28211|Alphaproteobacteria G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase GDHHQS3_k127_2701848_4 1121948.AUAC01000002_gene877 2.832e-142 459.0 COG0524@1|root,COG0524@2|Bacteria,1QNWF@1224|Proteobacteria,2TT7H@28211|Alphaproteobacteria,43XH4@69657|Hyphomonadaceae 28211|Alphaproteobacteria G pfkB family carbohydrate kinase - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB GDHHQS3_k127_2701848_10 565045.NOR51B_594 4.664e-27 125.0 COG0346@1|root,COG0346@2|Bacteria,1RIW7@1224|Proteobacteria 1224|Proteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_2701848_6 392499.Swit_1688 7.443e-68 246.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U6BM@28211|Alphaproteobacteria,2K23B@204457|Sphingomonadales 204457|Sphingomonadales P TonB-dependent receptor plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_2703849_4 627192.SLG_22570 0.0004604 43.0 COG0596@1|root,COG0596@2|Bacteria,1R3U1@1224|Proteobacteria,2TVFV@28211|Alphaproteobacteria,2KAG5@204457|Sphingomonadales 204457|Sphingomonadales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 GDHHQS3_k127_2703849_2 1121406.JAEX01000005_gene2904 6.977e-76 265.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM RarD protein, DMT superfamily transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA GDHHQS3_k127_2703849_0 1123073.KB899241_gene3413 5.639e-241 757.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1X38N@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon GDHHQS3_k127_2703849_3 472759.Nhal_3858 2.549e-28 119.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1WYXS@135613|Chromatiales 135613|Chromatiales S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 GDHHQS3_k127_2703849_1 1042377.AFPJ01000021_gene2122 1.234e-116 385.0 COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 GDHHQS3_k127_2705709_1 395961.Cyan7425_2892 5.907e-123 408.0 COG1136@1|root,COG2203@1|root,COG1136@2|Bacteria,COG2203@2|Bacteria,1G1SM@1117|Cyanobacteria,3KJGB@43988|Cyanothece 1117|Cyanobacteria V TIGRFAM ABC exporter ATP-binding subunit, DevA family - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_2705709_0 215803.DB30_4063 1.058e-231 729.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales 28221|Deltaproteobacteria Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 GDHHQS3_k127_2705709_2 666681.M301_1213 5.266e-44 165.0 COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria 28216|Betaproteobacteria P ABC-3 protein - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 GDHHQS3_k127_2705926_1 472759.Nhal_2673 4.263e-150 484.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon GDHHQS3_k127_2705926_0 1283300.ATXB01000001_gene693 1.391e-279 871.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XDMC@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD GDHHQS3_k127_2764206_6 1385517.N800_15095 3.103e-29 119.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - - - - - - - - - - HTH_5 GDHHQS3_k127_2764206_3 287.DR97_2946 5.208e-142 464.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1YEGQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N GDHHQS3_k127_2764206_2 713586.KB900536_gene2136 7.986e-162 527.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas GDHHQS3_k127_2764206_8 2340.JV46_22910 2.954e-12 72.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1J74P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P GDHHQS3_k127_2764206_7 371731.Rsw2DRAFT_3094 3.939e-13 72.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,1FC87@1060|Rhodobacter 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 GDHHQS3_k127_2764206_1 506534.Rhein_0267 7.559e-163 524.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales 135613|Chromatiales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N GDHHQS3_k127_2764206_4 380358.XALC_0002 3.387e-129 422.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1X3F0@135614|Xanthomonadales 135614|Xanthomonadales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 GDHHQS3_k127_2764206_5 1384054.N790_12355 1.704e-68 246.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1X3R9@135614|Xanthomonadales 135614|Xanthomonadales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_23,SMC_N GDHHQS3_k127_2764206_0 713586.KB900536_gene2143 0.0 1107.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim GDHHQS3_k127_277378_3 497321.C664_14194 1.031e-70 243.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KVNK@206389|Rhodocyclales 206389|Rhodocyclales C Part of a membrane complex involved in electron transport - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 GDHHQS3_k127_277378_2 1056512.D515_03322 1.266e-82 278.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1XSIP@135623|Vibrionales 135623|Vibrionales C Part of a membrane complex involved in electron transport rnfA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03617 - - - - ko00000 - - - Rnf-Nqr GDHHQS3_k127_277378_0 519989.ECTPHS_09088 4.695e-299 930.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales 135613|Chromatiales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind GDHHQS3_k127_277378_1 1384054.N790_09075 1.051e-92 314.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1X4VI@135614|Xanthomonadales 135614|Xanthomonadales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA GDHHQS3_k127_2787171_10 247634.GPB2148_746 6.85e-104 346.0 COG0183@1|root,COG0183@2|Bacteria,1QE43@1224|Proteobacteria,1RZQI@1236|Gammaproteobacteria,1J5BQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Thiolase, C-terminal domain - - - - - - - - - - - - Thiolase_C,Thiolase_N GDHHQS3_k127_2787171_2 1121937.AUHJ01000007_gene1769 5.429e-202 634.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1RRAB@1236|Gammaproteobacteria,469HS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N GDHHQS3_k127_2787171_3 247634.GPB2148_849 2.574e-186 599.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T3JY@1236|Gammaproteobacteria,1J7N2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C GDHHQS3_k127_2787171_8 1121937.AUHJ01000007_gene1777 2.792e-111 368.0 COG1733@1|root,COG1733@2|Bacteria,1R4WK@1224|Proteobacteria,1S7FZ@1236|Gammaproteobacteria,46B25@72275|Alteromonadaceae 1236|Gammaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GDHHQS3_k127_2787171_15 1121937.AUHJ01000017_gene3019 6.542e-37 147.0 COG0662@1|root,COG0662@2|Bacteria,1N5XM@1224|Proteobacteria,1SC7V@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Lipocalin-like domain - - - - - - - - - - - - Lipocalin_5 GDHHQS3_k127_2787171_1 1161401.ASJA01000005_gene2487 8.066e-205 653.0 COG1012@1|root,COG1012@2|Bacteria,1MY4N@1224|Proteobacteria,2TV5F@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Aldehyde dehydrogenase family paaN - - - - - - - - - - - Aldedh GDHHQS3_k127_2787171_9 1161401.ASJA01000005_gene2499 1.205e-110 371.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,43WIT@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding GDHHQS3_k127_2787171_7 1161401.ASJA01000005_gene2502 1.073e-111 366.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2TTEP@28211|Alphaproteobacteria,43XY0@69657|Hyphomonadaceae 28211|Alphaproteobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 GDHHQS3_k127_2787171_0 317655.Sala_1008 7.809e-237 740.0 COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,2K2TY@204457|Sphingomonadales 204457|Sphingomonadales Q Retinal pigment epithelial membrane protein - - 1.13.11.82 ko:K11159,ko:K21822 - - - - ko00000,ko01000 - - - RPE65 GDHHQS3_k127_2787171_11 314285.KT71_02277 6.801e-103 351.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RZG3@1236|Gammaproteobacteria,1J5K2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf GDHHQS3_k127_2787171_13 1265313.HRUBRA_02318 8.208e-83 301.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1J527@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GDHHQS3_k127_2787171_5 1265313.HRUBRA_02301 4.107e-131 434.0 COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1J8AD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase,HAD GDHHQS3_k127_2787171_17 314278.NB231_01678 6.929e-18 96.0 COG3945@1|root,COG3945@2|Bacteria,1NDGV@1224|Proteobacteria,1SGA3@1236|Gammaproteobacteria,1X27K@135613|Chromatiales 135613|Chromatiales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin GDHHQS3_k127_2787171_16 1151061.CAJY01000039_gene3541 1.798e-31 135.0 COG1075@1|root,COG1075@2|Bacteria,2GJGC@201174|Actinobacteria 201174|Actinobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - GDHHQS3_k127_2787171_4 1161401.ASJA01000005_gene2474 1.148e-178 572.0 COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,43Y7G@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes - - - - - - - - - - - - RPE65 GDHHQS3_k127_2787171_12 1121937.AUHJ01000007_gene1774 1.509e-84 289.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,464RH@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short GDHHQS3_k127_2787171_6 1282876.BAOK01000001_gene2101 1.025e-111 369.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TRZS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO GDHHQS3_k127_2787171_19 1121937.AUHJ01000007_gene1773 1.904e-10 65.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - DUF1295 GDHHQS3_k127_2787171_14 1123279.ATUS01000001_gene1291 7.265e-75 263.0 COG1733@1|root,COG1733@2|Bacteria,1R4WK@1224|Proteobacteria,1S7FZ@1236|Gammaproteobacteria,1JA84@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GDHHQS3_k127_2787171_18 565045.NOR51B_571 3.14e-17 82.0 COG1574@1|root,COG1574@2|Bacteria,1MXST@1224|Proteobacteria,1RS60@1236|Gammaproteobacteria,1J7XW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 GDHHQS3_k127_2868776_1 1042377.AFPJ01000021_gene2122 1.894e-153 495.0 COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 GDHHQS3_k127_2868776_4 472759.Nhal_3858 8.526e-29 120.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1WYXS@135613|Chromatiales 135613|Chromatiales S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 GDHHQS3_k127_2868776_0 1123073.KB899241_gene3413 4.118e-241 757.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1X38N@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon GDHHQS3_k127_2868776_2 641491.DND132_1053 8.085e-77 267.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM RarD protein, DMT superfamily transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA GDHHQS3_k127_2868776_3 1288494.EBAPG3_11070 3.721e-36 145.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2VU6X@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 GDHHQS3_k127_2886348_0 1121015.N789_11445 6.191e-139 452.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1X31N@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 GDHHQS3_k127_2886348_1 1260251.SPISAL_02375 4.205e-54 194.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase GDHHQS3_k127_2886348_2 935567.JAES01000018_gene1413 9.97e-38 147.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1X6GZ@135614|Xanthomonadales 135614|Xanthomonadales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB GDHHQS3_k127_2886348_3 1169143.KB911052_gene5757 5.131e-21 94.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,1K08C@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GDHHQS3_k127_2890463_5 1348583.ATLH01000029_gene1153 0.00055 46.0 2DUW9@1|root,33SPC@2|Bacteria,4P1AG@976|Bacteroidetes,1I792@117743|Flavobacteriia,1F9Z1@104264|Cellulophaga 976|Bacteroidetes S von Willebrand factor type A domain - - - - - - - - - - - - VWA_3 GDHHQS3_k127_2890463_3 715451.ambt_00990 4.131e-05 49.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - - - - - - - - - - - FHA,Trans_reg_C,Yop-YscD_cpl GDHHQS3_k127_2890463_0 1127673.GLIP_0097 1.309e-62 224.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Pfam MotA TolQ ExbB proton channel family - - - - - - - - - - - - MotA_ExbB GDHHQS3_k127_2890463_4 1157640.AQWO01000005_gene2183 0.0001757 54.0 COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K01990,ko:K21397 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl GDHHQS3_k127_2890463_2 614083.AWQR01000055_gene1978 8.42e-23 115.0 COG0515@1|root,COG2114@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,4AB4Y@80864|Comamonadaceae 28216|Betaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Pkinase GDHHQS3_k127_2890463_1 1280944.HY17_19140 5.937e-58 228.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,43ZFH@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,TIR_2 GDHHQS3_k127_2901353_0 378806.STAUR_1294 4.379e-212 679.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,42S4X@68525|delta/epsilon subdivisions,2WNPW@28221|Deltaproteobacteria,2YU9Y@29|Myxococcales 28221|Deltaproteobacteria O Peptidase family M13 - - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_2901353_3 1384054.N790_09605 4.504e-22 110.0 COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - GT87 GDHHQS3_k127_2901353_1 452637.Oter_0991 1.009e-152 506.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,46V2N@74201|Verrucomicrobia,3K73R@414999|Opitutae 2|Bacteria T PFAM adenylyl cyclase class-3 4 guanylyl cyclase cyaD1 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc GDHHQS3_k127_2901353_2 452637.Oter_0990 8.387e-31 129.0 2EKQ4@1|root,33EDV@2|Bacteria 2|Bacteria S Bacterial SH3 domain homologues - - - - - - - - - - - - SH3_3 GDHHQS3_k127_2953760_1 1122176.KB903542_gene354 5.312e-78 270.0 COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,1IQN1@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA GDHHQS3_k127_2953760_0 760192.Halhy_1886 1.256e-146 475.0 COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,1IPIT@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_2953760_2 1123073.KB899241_gene2348 2.451e-77 265.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1X60Y@135614|Xanthomonadales 135614|Xanthomonadales F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase GDHHQS3_k127_2959091_12 477228.YO5_05809 1.322e-25 108.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1Z2BE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD GDHHQS3_k127_2959091_3 323261.Noc_1722 3.982e-103 346.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales 135613|Chromatiales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA GDHHQS3_k127_2959091_2 1123073.KB899243_gene779 1.261e-109 370.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales 135614|Xanthomonadales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N GDHHQS3_k127_2959091_1 396588.Tgr7_2714 1.239e-149 499.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales 135613|Chromatiales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C GDHHQS3_k127_2959091_4 1333856.L686_08430 6.492e-74 262.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0JM@1236|Gammaproteobacteria,1Z2GR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E aminopeptidase - - - - - - - - - - - - Aminopep GDHHQS3_k127_2959091_6 1121004.ATVC01000044_gene773 9.433e-52 186.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,2KR7X@206351|Neisseriales 206351|Neisseriales C Belongs to the MsrB Met sulfoxide reductase family trh1 - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR GDHHQS3_k127_2959091_5 1044.EH31_16610 2.684e-53 196.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales 204457|Sphingomonadales S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase GDHHQS3_k127_2959091_9 189753.AXAS01000063_gene3512 6.291e-34 132.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3 GDHHQS3_k127_2959091_15 1265502.KB905948_gene982 2.61e-12 68.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2VJ4E@28216|Betaproteobacteria,4ABMB@80864|Comamonadaceae 28216|Betaproteobacteria I PFAM fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase,YhhN GDHHQS3_k127_2959091_7 1045855.DSC_09865 5.532e-41 152.0 COG2161@1|root,COG2161@2|Bacteria,1MZ6E@1224|Proteobacteria,1SD5I@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox GDHHQS3_k127_2959091_8 1266908.AQPB01000059_gene2663 2.203e-40 154.0 COG3668@1|root,COG3668@2|Bacteria,1N8NU@1224|Proteobacteria,1SPUN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Plasmid stabilization system - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_2959091_10 1120983.KB894575_gene524 3.663e-32 130.0 COG2050@1|root,COG2050@2|Bacteria,1MYM3@1224|Proteobacteria,2U5K2@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protein possibly involved in aromatic compounds catabolism MA20_08885 - - - - - - - - - - - 4HBT GDHHQS3_k127_2959091_0 1122603.ATVI01000006_gene831 7.662e-180 573.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,1RPW8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome p450 - - - - - - - - - - - - p450 GDHHQS3_k127_2959091_13 360094.PXO_00079 1.341e-23 105.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,zf-ISL3 GDHHQS3_k127_2959091_11 1415779.JOMH01000001_gene563 2.958e-26 110.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1X3Z7@135614|Xanthomonadales 135614|Xanthomonadales I Acyltransferase aas - - - - - - - - - - - Acyltransferase,MFS_1 GDHHQS3_k127_298036_1 1117315.AHCA01000006_gene2977 6.658e-11 69.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,2Q2IQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl GDHHQS3_k127_298036_2 1278309.KB907106_gene1371 1.034e-05 56.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1XRFR@135619|Oceanospirillales 135619|Oceanospirillales NU Type IV Pilus-assembly protein W - - - - - - - - - - - - N_methyl,PilW GDHHQS3_k127_298036_0 1283300.ATXB01000001_gene79 9.821e-13 77.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1XFI4@135618|Methylococcales 135618|Methylococcales NU TIGRFAM Pilus modification type IV, PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_30011_0 1049564.TevJSym_au00270 4.669e-293 910.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1J4ZW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C GDHHQS3_k127_30011_6 1123377.AUIV01000005_gene1607 1.83e-39 148.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales 135614|Xanthomonadales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding GDHHQS3_k127_30011_8 106648.BBLJ01000011_gene1070 1.917e-15 77.0 2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_30011_3 935863.AWZR01000006_gene1369 1.773e-115 396.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales 135614|Xanthomonadales O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 GDHHQS3_k127_30011_2 1384054.N790_06185 1.004e-115 378.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1X4CF@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes a key regulatory step in fatty acid biosynthesis - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 GDHHQS3_k127_30011_1 998088.B565_1429 1.82e-168 542.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,1Y3ZK@135624|Aeromonadales 135624|Aeromonadales F Amidohydrolase family - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 GDHHQS3_k127_30011_7 1173025.GEI7407_1238 5.272e-25 110.0 COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1HCVK@1150|Oscillatoriales 1117|Cyanobacteria S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic GDHHQS3_k127_30011_4 1123073.KB899243_gene601 9.139e-56 198.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S6VE@1236|Gammaproteobacteria,1X5JD@135614|Xanthomonadales 135614|Xanthomonadales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR GDHHQS3_k127_30011_5 1121015.N789_06080 7.469e-52 196.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family mopB - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 GDHHQS3_k127_3008131_1 1232410.KI421412_gene166 1.892e-151 488.0 COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales 28221|Deltaproteobacteria C Alanine dehydrogenase/PNT, C-terminal domain bamQ - 1.1.1.368 ko:K07538 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05581 RC00850 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N GDHHQS3_k127_3008131_2 316067.Geob_0098 1.79e-91 308.0 COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 GDHHQS3_k127_3008131_0 85643.Tmz1t_2953 2.227e-188 594.0 COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2VPM9@28216|Betaproteobacteria,2KVX4@206389|Rhodocyclales 206389|Rhodocyclales I Enoyl-CoA hydratase/isomerase - - 3.7.1.21 ko:K07539 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05593,R05594,R10696 RC01430,RC01431,RC03237 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 GDHHQS3_k127_3008131_3 876044.IMCC3088_215 6.279e-65 234.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1T3IM@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_305451_1 748247.AZKH_0434 1.136e-125 408.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,2KZSM@206389|Rhodocyclales 206389|Rhodocyclales H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_305451_0 1121918.ARWE01000001_gene383 8.574e-251 781.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,43T3E@69541|Desulfuromonadales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_3067240_1 1123368.AUIS01000014_gene2314 5.783e-161 536.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,2NC9Z@225057|Acidithiobacillales 225057|Acidithiobacillales H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE GDHHQS3_k127_3067240_0 715451.ambt_14275 2.449e-176 573.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,464W2@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase pepN - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 GDHHQS3_k127_3067240_2 765911.Thivi_3483 5.284e-80 271.0 COG0457@1|root,COG4715@1|root,COG0457@2|Bacteria,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,1S0TU@1236|Gammaproteobacteria,1WXSB@135613|Chromatiales 135613|Chromatiales S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM GDHHQS3_k127_3089764_3 518766.Rmar_0401 5.112e-40 152.0 COG3304@1|root,COG3304@2|Bacteria,4P9H5@976|Bacteroidetes,1FKBZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Inner membrane component domain - - - - - - - - - - - - YccF GDHHQS3_k127_3089764_1 472759.Nhal_0251 8.43e-103 342.0 COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales 135613|Chromatiales L PFAM Transposase IS200 like - - - - - - - - - - - - Y1_Tnp GDHHQS3_k127_3089764_2 565045.NOR51B_190 2.261e-99 336.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1J569@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK GDHHQS3_k127_3089764_0 1216007.AOPM01000024_gene3056 4.705e-110 370.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,2PZFT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 GDHHQS3_k127_3089764_4 1384056.N787_11090 1.477e-20 92.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1X3S4@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b GDHHQS3_k127_3114925_0 1207063.P24_08594 1.285e-206 670.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2JQIX@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the GcvT family - - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 GDHHQS3_k127_3114925_3 43354.JOIJ01000006_gene1943 2.159e-09 66.0 COG4583@1|root,COG4583@2|Bacteria,2HJE7@201174|Actinobacteria,4E4X2@85010|Pseudonocardiales 201174|Actinobacteria E Sarcosine oxidase, gamma subunit family soxG - 1.5.3.1 ko:K00305 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxG GDHHQS3_k127_3114925_1 1122194.AUHU01000004_gene1430 1.495e-91 314.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,465BY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N GDHHQS3_k127_3114925_2 380703.AHA_1040 3.84e-80 272.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1Y51Z@135624|Aeromonadales 135624|Aeromonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C GDHHQS3_k127_3121567_1 448385.sce2299 3.101e-132 433.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales 28221|Deltaproteobacteria H Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC GDHHQS3_k127_3121567_5 1517416.IDAT_10430 1.536e-21 96.0 2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,1SCC9@1236|Gammaproteobacteria,2QH16@267893|Idiomarinaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RHH_3 GDHHQS3_k127_3121567_4 396595.TK90_2100 4.274e-31 123.0 COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,1SDK6@1236|Gammaproteobacteria,1WZ7U@135613|Chromatiales 135613|Chromatiales DJ PFAM plasmid - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin GDHHQS3_k127_3121567_0 1123400.KB904758_gene2205 7.111e-155 498.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0798 Arsenite efflux pump ACR3 and related permeases arsB - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF GDHHQS3_k127_3121567_2 1123368.AUIS01000014_gene2288 1.05e-56 200.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,2NCUY@225057|Acidithiobacillales 225057|Acidithiobacillales T low molecular weight - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc GDHHQS3_k127_3121567_3 743720.Psefu_3308 6.236e-53 191.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1S52P@1236|Gammaproteobacteria,1YXDB@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Glycine zipper 2TM domain ycfJ - - - - - - - - - - - Rick_17kDa_Anti GDHHQS3_k127_3335880_0 83406.HDN1F_19940 6e-323 991.0 COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,1RPYS@1236|Gammaproteobacteria,1J6N5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S FAD binding domain - - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 GDHHQS3_k127_3335880_1 1268622.AVS7_03385 4.087e-144 461.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2VV5Q@28216|Betaproteobacteria,4AF8V@80864|Comamonadaceae 28216|Betaproteobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF GDHHQS3_k127_3335880_2 1396858.Q666_10220 4.886e-43 161.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,1RRA5@1236|Gammaproteobacteria,46AE0@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N GDHHQS3_k127_3378494_5 509190.Cseg_0124 0.0002065 44.0 COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,2UA0K@28211|Alphaproteobacteria,2KH61@204458|Caulobacterales 204458|Caulobacterales S MAPEG family - - - - - - - - - - - - MAPEG GDHHQS3_k127_3378494_0 935863.AWZR01000001_gene2077 2.842e-110 359.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1X3J3@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim GDHHQS3_k127_3378494_4 876044.IMCC3088_250 5.1e-11 70.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Von willebrand factor, type a - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 GDHHQS3_k127_3378494_2 1123073.KB899241_gene2200 8.572e-100 331.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,1X4ZK@135614|Xanthomonadales 135614|Xanthomonadales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C GDHHQS3_k127_3378494_1 1384056.N787_06150 3.604e-110 381.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,1X4YC@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA GDHHQS3_k127_3378494_3 1496688.ER33_14755 5.855e-18 85.0 COG1848@1|root,COG1848@2|Bacteria,1GMT6@1117|Cyanobacteria,22TVN@167375|Cyanobium 1117|Cyanobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07064 - - - - ko00000 - - - PIN GDHHQS3_k127_3389980_4 1121396.KB892983_gene4263 6.371e-05 46.0 COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,43BQR@68525|delta/epsilon subdivisions,2X71T@28221|Deltaproteobacteria,2MKDF@213118|Desulfobacterales 28221|Deltaproteobacteria G Sugar (and other) transporter - - - - - - - - - - - - MFS_1 GDHHQS3_k127_3389980_1 414684.RC1_1744 1.372e-178 568.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JQCM@204441|Rhodospirillales 204441|Rhodospirillales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N GDHHQS3_k127_3389980_0 1123261.AXDW01000033_gene2110 3.713e-262 825.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X4U6@135614|Xanthomonadales 135614|Xanthomonadales I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1 GDHHQS3_k127_3389980_2 1030157.AFMP01000026_gene1056 6.126e-162 525.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2K16K@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_3389980_3 1179773.BN6_46520 1.964e-87 300.0 COG2141@1|root,COG2141@2|Bacteria,2IEM9@201174|Actinobacteria 201174|Actinobacteria C Luciferase-like monooxygenase - - 1.5.98.2 ko:K00320 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R04464 RC01607 ko00000,ko00001,ko00002,ko01000 - - - Bac_luciferase GDHHQS3_k127_3395854_2 158500.BV97_01748 4.1e-09 66.0 COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2UF6H@28211|Alphaproteobacteria,2K30F@204457|Sphingomonadales 204457|Sphingomonadales S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_3395854_0 1121428.DESHY_80025___1 5.871e-73 260.0 COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia,261ZI@186807|Peptococcaceae 186801|Clostridia M PFAM NAD-dependent epimerase dehydratase rfbG - 4.2.1.45 ko:K01709 ko00520,map00520 - R02426 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd GDHHQS3_k127_3395854_1 1121445.ATUZ01000011_gene658 8.189e-13 74.0 COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MCW@68525|delta/epsilon subdivisions,2WIYK@28221|Deltaproteobacteria,2M8ZW@213115|Desulfovibrionales 28221|Deltaproteobacteria JM TIGRFAM Glucose-1-phosphate cytidylyltransferase rfbF - 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R00956 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase GDHHQS3_k127_3402696_6 349124.Hhal_2347 1.273e-19 97.0 COG0515@1|root,COG0515@2|Bacteria 349124.Hhal_2347|- KLT protein kinase activity - - - - - - - - - - - - - GDHHQS3_k127_3402696_1 1453501.JELR01000002_gene593 1.4e-149 486.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,465BJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase amaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_3402696_0 1384054.N790_05135 2.251e-199 636.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X4H6@135614|Xanthomonadales 135614|Xanthomonadales M gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept GDHHQS3_k127_3402696_5 1304883.KI912532_gene1248 3.154e-38 145.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KX13@206389|Rhodocyclales 206389|Rhodocyclales C Ferredoxin - - - - - - - - - - - - Fer4 GDHHQS3_k127_3402696_2 1384054.N790_05120 5.275e-63 220.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1X5VI@135614|Xanthomonadales 135614|Xanthomonadales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GDHHQS3_k127_3402696_4 1056820.KB900634_gene1945 5.57e-41 158.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,2PNJY@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L Conserved hypothetical protein 95 rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 GDHHQS3_k127_3402696_3 1123517.JOMR01000001_gene407 9.874e-48 180.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,4605U@72273|Thiotrichales 72273|Thiotrichales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N GDHHQS3_k127_3410518_1 497964.CfE428DRAFT_4183 2.057e-107 355.0 COG1232@1|root,COG1232@2|Bacteria,46TGR@74201|Verrucomicrobia 74201|Verrucomicrobia H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase GDHHQS3_k127_3410518_2 234267.Acid_4640 4.666e-85 290.0 COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria 57723|Acidobacteria GM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane GDHHQS3_k127_3410518_3 525904.Tter_2802 1.4e-81 278.0 COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria 2|Bacteria GM ATPases associated with a variety of cellular activities - - 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 - - ABC_tran,Wzt_C GDHHQS3_k127_3410518_0 565045.NOR51B_571 1.491e-218 702.0 COG1574@1|root,COG1574@2|Bacteria,1MXST@1224|Proteobacteria,1RS60@1236|Gammaproteobacteria,1J7XW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 GDHHQS3_k127_3411679_3 519989.ECTPHS_03387 1.437e-56 205.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1X2F6@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase M17 family - - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3663,Peptidase_M17 GDHHQS3_k127_3411679_0 1500890.JQNL01000001_gene2538 4.278e-143 470.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X3EN@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase S1C family htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 GDHHQS3_k127_3411679_2 1283300.ATXB01000001_gene566 3.403e-85 289.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1XFYM@135618|Methylococcales 135618|Methylococcales L HNH endonuclease - - - - - - - - - - - - HNH_5 GDHHQS3_k127_3411679_1 1500890.JQNL01000001_gene2960 2.584e-88 300.0 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1X448@135614|Xanthomonadales 135614|Xanthomonadales L Exodeoxyribonuclease IX exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N GDHHQS3_k127_3411679_4 1123073.KB899241_gene1776 3.549e-50 196.0 COG3391@1|root,COG3391@2|Bacteria,1NC58@1224|Proteobacteria 1224|Proteobacteria S amine dehydrogenase activity - - - - - - - - - - - - TPR_19 GDHHQS3_k127_3416887_2 472759.Nhal_2202 3.711e-70 239.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N GDHHQS3_k127_3416887_0 1123256.KB907929_gene3378 2.319e-109 364.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1X4F8@135614|Xanthomonadales 135614|Xanthomonadales L glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 GDHHQS3_k127_3416887_1 1122603.ATVI01000005_gene3497 1.792e-100 351.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_3416887_4 1123073.KB899241_gene1786 5.871e-35 135.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1X7KK@135614|Xanthomonadales 135614|Xanthomonadales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX - - - - - - - - - - - Iron_traffic GDHHQS3_k127_3416887_3 1282360.ABAC460_16250 3.914e-42 158.0 29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,2UKUZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 GDHHQS3_k127_3416887_5 700598.Niako_2344 1.22e-33 149.0 COG1216@1|root,COG1216@2|Bacteria,4NPNF@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF616) - - - - - - - - - - - - DUF616 GDHHQS3_k127_3416947_2 1121015.N789_00420 3.529e-12 68.0 2EUIT@1|root,33N0U@2|Bacteria,1NMNE@1224|Proteobacteria,1SHKN@1236|Gammaproteobacteria,1X7TN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_3416947_0 697282.Mettu_1061 0.0 1431.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C GDHHQS3_k127_3416947_1 1255043.TVNIR_1572 7.451e-55 194.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C GDHHQS3_k127_3422408_29 1547437.LL06_23045 5.975e-37 141.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,43JHB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria BQ including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl GDHHQS3_k127_3422408_31 1292020.H483_0114515 1.917e-27 119.0 COG0824@1|root,COG0824@2|Bacteria,2ISIV@201174|Actinobacteria 201174|Actinobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 GDHHQS3_k127_3422408_22 565045.NOR51B_2692 2.077e-63 227.0 28NHW@1|root,33UXZ@2|Bacteria,1NVCE@1224|Proteobacteria,1SNM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3422408_15 743720.Psefu_1896 5.309e-82 287.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,1YWXU@136845|Pseudomonas putida group 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - - GDHHQS3_k127_3422408_5 237368.SCABRO_00745 1.061e-132 437.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily ycaD - - - - - - - - - - - MFS_1,Sugar_tr GDHHQS3_k127_3422408_4 748247.AZKH_p0307 4.294e-191 602.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2VJCK@28216|Betaproteobacteria,2KZ15@206389|Rhodocyclales 206389|Rhodocyclales C Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 GDHHQS3_k127_3422408_27 742159.HMPREF0004_4362 3.782e-46 173.0 2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2VSQ3@28216|Betaproteobacteria,3T6ZC@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 GDHHQS3_k127_3422408_19 105559.Nwat_0152 1.216e-76 270.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales 135613|Chromatiales S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA GDHHQS3_k127_3422408_30 311403.Arad_3392 1.447e-32 132.0 COG0454@1|root,COG0456@2|Bacteria,1N09D@1224|Proteobacteria,2UBWZ@28211|Alphaproteobacteria,4BFU6@82115|Rhizobiaceae 28211|Alphaproteobacteria K Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring - - 2.3.1.82 ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1 GDHHQS3_k127_3422408_25 130081.XP_005706629.1 2.145e-49 201.0 COG0439@1|root,2RN4Y@2759|Eukaryota 2759|Eukaryota I ATP-grasp domain - - 6.3.2.11 ko:K14755 ko00330,ko00340,ko00410,map00330,map00340,map00410 - R00910,R00912,R01164,R01991,R03286 RC00064,RC00090 ko00000,ko00001,ko01000 - - - ATP-grasp_4 GDHHQS3_k127_3422408_24 1232410.KI421421_gene3684 2.145e-49 201.0 COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales 28221|Deltaproteobacteria M ATP-grasp domain - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C GDHHQS3_k127_3422408_28 187272.Mlg_1582 5.221e-46 173.0 COG3034@1|root,COG3034@2|Bacteria,1QE27@1224|Proteobacteria,1SKB4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD GDHHQS3_k127_3422408_37 243233.MCA0605 8.044e-06 52.0 2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,1SHZI@1236|Gammaproteobacteria,1XFQZ@135618|Methylococcales 135618|Methylococcales S Alanine-zipper, major outer membrane lipoprotein - - - - - - - - - - - - Alanine_zipper GDHHQS3_k127_3422408_10 1283300.ATXB01000001_gene2393 8.025e-102 345.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XE3K@135618|Methylococcales 135618|Methylococcales M PFAM YkuD domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - YkuD GDHHQS3_k127_3422408_36 1122180.Lokhon_01629 2.249e-07 60.0 COG3218@1|root,COG3218@2|Bacteria,1PHIY@1224|Proteobacteria,2VC87@28211|Alphaproteobacteria,2PA33@245186|Loktanella 28211|Alphaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - - - - - - - - - - - GDHHQS3_k127_3422408_35 582515.KR51_00027560 1.557e-07 63.0 COG1463@1|root,COG1463@2|Bacteria,1G1A7@1117|Cyanobacteria 1117|Cyanobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component ycf22 - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD GDHHQS3_k127_3422408_16 1380391.JIAS01000013_gene3761 1.73e-81 278.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQTF@204441|Rhodospirillales 204441|Rhodospirillales Q ATPases associated with a variety of cellular activities - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran GDHHQS3_k127_3422408_20 1121374.KB891586_gene2762 2.149e-75 267.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component mlaE_1 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 GDHHQS3_k127_3422408_23 1380391.JIAS01000020_gene1408 1.286e-52 194.0 COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VFPM@28211|Alphaproteobacteria,2JWWJ@204441|Rhodospirillales 204441|Rhodospirillales IQ KR domain - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_3422408_18 402881.Plav_1710 6.056e-78 275.0 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria,1JNHM@119043|Rhodobiaceae 28211|Alphaproteobacteria EGP MFS_1 like family - - - - - - - - - - - - MFS_1 GDHHQS3_k127_3422408_3 228405.HNE_1303 4.807e-216 685.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,43XB8@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 GDHHQS3_k127_3422408_0 29581.BW37_05230 0.0 1189.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,475Z8@75682|Oxalobacteraceae 28216|Betaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_3422408_11 1500894.JQNN01000001_gene467 1.67e-97 332.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family nolF - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 GDHHQS3_k127_3422408_13 264462.Bd3564 2.856e-90 306.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2MTS4@213481|Bdellovibrionales,2WJ3N@28221|Deltaproteobacteria 213481|Bdellovibrionales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1986 Pan_kinase GDHHQS3_k127_3422408_14 765869.BDW_13125 7.16e-89 307.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2MT56@213481|Bdellovibrionales,2WIR1@28221|Deltaproteobacteria 213481|Bdellovibrionales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein GDHHQS3_k127_3422408_17 1191523.MROS_1795 6.851e-80 280.0 COG0414@1|root,COG0414@2|Bacteria 2|Bacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase GDHHQS3_k127_3422408_12 765869.BDW_13115 2.261e-92 312.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2MSX4@213481|Bdellovibrionales,2WIQK@28221|Deltaproteobacteria 213481|Bdellovibrionales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf GDHHQS3_k127_3422408_26 1089439.KB902240_gene904 2.898e-48 182.0 COG5495@1|root,COG5495@2|Bacteria,1N50Y@1224|Proteobacteria,1SBC4@1236|Gammaproteobacteria,462MA@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF2520) - - - - - - - - - - - - DUF2520 GDHHQS3_k127_3422408_7 1163617.SCD_n02608 6.499e-131 432.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VIZB@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - ko:K11102 - - - - ko00000,ko02000 2.A.23.1.1,2.A.23.1.2 - - SDF GDHHQS3_k127_3422408_2 472759.Nhal_2311 1.173e-246 784.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales 135613|Chromatiales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N GDHHQS3_k127_3422408_8 697282.Mettu_2833 2.324e-130 422.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1XE9F@135618|Methylococcales 135618|Methylococcales O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 GDHHQS3_k127_3422408_21 1121015.N789_10160 3.136e-64 237.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1RAQ0@1224|Proteobacteria,1RP2P@1236|Gammaproteobacteria,1X4CX@135614|Xanthomonadales 135614|Xanthomonadales S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE,ThrE_2 GDHHQS3_k127_3422408_9 595460.RRSWK_03194 3.16e-129 428.0 COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes 203682|Planctomycetes P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N GDHHQS3_k127_3422408_34 1249627.D779_3900 8.938e-20 96.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1WZDM@135613|Chromatiales 135613|Chromatiales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 GDHHQS3_k127_3422408_6 1049564.TevJSym_af00130 2.11e-132 429.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1J5VE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C GDHHQS3_k127_3422408_1 745411.B3C1_10727 1.137e-274 860.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1J8W5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S oligopeptide transporter - - - - - - - - - - - - OPT GDHHQS3_k127_3422408_32 1439940.BAY1663_00976 7.129e-27 118.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA GDHHQS3_k127_3425696_8 754476.Q7A_2479 1.126e-18 87.0 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,46193@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 GDHHQS3_k127_3425696_5 765912.Thimo_0632 4.367e-45 169.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1WXYX@135613|Chromatiales 135613|Chromatiales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ GDHHQS3_k127_3425696_3 292415.Tbd_2504 1.274e-63 229.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,1KSYB@119069|Hydrogenophilales 119069|Hydrogenophilales E Shikimate dehydrogenase substrate binding domain - - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N GDHHQS3_k127_3425696_0 713586.KB900536_gene2241 2.185e-155 496.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales 135613|Chromatiales H Belongs to the ALAD family - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD GDHHQS3_k127_3425696_2 1123073.KB899241_gene2259 1.5e-65 231.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1X5C6@135614|Xanthomonadales 135614|Xanthomonadales D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 GDHHQS3_k127_3425696_4 1049564.TevJSym_as00580 8.773e-56 204.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C GDHHQS3_k127_3425696_6 1232683.ADIMK_3296 3.413e-38 153.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,466ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 GDHHQS3_k127_3425696_1 314278.NB231_10753 3.683e-75 261.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1S296@1236|Gammaproteobacteria,1X2D7@135613|Chromatiales 135613|Chromatiales L Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos GDHHQS3_k127_3425696_7 713587.THITH_16390 6.942e-22 106.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L GDHHQS3_k127_342657_0 2340.JV46_27120 7.568e-130 416.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 GDHHQS3_k127_342657_3 396588.Tgr7_0971 6.098e-37 146.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1WY2F@135613|Chromatiales 135613|Chromatiales O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE GDHHQS3_k127_342657_1 243233.MCA1860 3.46e-117 404.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XDJB@135618|Methylococcales 135618|Methylococcales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N GDHHQS3_k127_342657_2 1121015.N789_00510 1.581e-42 157.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1X6F1@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR GDHHQS3_k127_3427542_7 1234364.AMSF01000024_gene3787 9.233e-62 231.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X30G@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 GDHHQS3_k127_3427542_2 1384054.N790_02575 8.372e-169 539.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1X3IA@135614|Xanthomonadales 135614|Xanthomonadales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA GDHHQS3_k127_3427542_3 1123073.KB899241_gene1999 1.085e-141 454.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1X36R@135614|Xanthomonadales 135614|Xanthomonadales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA GDHHQS3_k127_3427542_1 666685.R2APBS1_0699 4.784e-177 570.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1X3Q1@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase GDHHQS3_k127_3427542_6 644801.Psest_0708 4.343e-71 251.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1Z084@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO GDHHQS3_k127_3427542_4 768066.HELO_1330 5.653e-106 353.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GDHHQS3_k127_3427542_5 765910.MARPU_10365 4.78e-83 284.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1WX0I@135613|Chromatiales 135613|Chromatiales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 GDHHQS3_k127_3427542_0 247633.GP2143_11292 3.608e-201 651.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,1J4T5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0457 FOG TPR repeat - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 GDHHQS3_k127_3427542_8 1173028.ANKO01000052_gene1631 9.264e-20 93.0 COG2008@1|root,COG2008@2|Bacteria,1G1VY@1117|Cyanobacteria,1H7SC@1150|Oscillatoriales 1117|Cyanobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GDHHQS3_k127_3429098_1 243233.MCA0707 2.805e-228 713.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XER9@135618|Methylococcales 135618|Methylococcales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 GDHHQS3_k127_3429098_0 1121374.KB891575_gene1102 1.829e-232 737.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 GDHHQS3_k127_3429098_2 1122137.AQXF01000003_gene2089 3.448e-186 602.0 COG1629@1|root,COG1629@2|Bacteria,1QUTW@1224|Proteobacteria,2TW7F@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_3430627_1 1385517.N800_12300 8.015e-221 702.0 COG0739@1|root,COG1680@1|root,COG0739@2|Bacteria,COG1680@2|Bacteria,1PI1J@1224|Proteobacteria,1TDYR@1236|Gammaproteobacteria,1XB7D@135614|Xanthomonadales 135614|Xanthomonadales V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - - GDHHQS3_k127_3430627_2 1121878.AUGL01000006_gene753 4.103e-176 571.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S0VJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O cysteine protease - - - - - - - - - - - - Peptidase_C1 GDHHQS3_k127_3430627_7 472759.Nhal_1647 1.724e-37 144.0 COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,1T3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE GDHHQS3_k127_3430627_8 1517416.IDAT_06290 8.204e-37 147.0 COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 GDHHQS3_k127_3430627_0 1385935.N836_20045 1.093e-316 993.0 COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1H7PF@1150|Oscillatoriales 1117|Cyanobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 GDHHQS3_k127_3430627_10 1266925.JHVX01000022_gene1759 8.867e-24 109.0 2E6CY@1|root,3310K@2|Bacteria,1NFYR@1224|Proteobacteria,2WBBD@28216|Betaproteobacteria,372S0@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3430627_9 926550.CLDAP_10800 3.535e-26 113.0 2E4GK@1|root,32ZBS@2|Bacteria 2|Bacteria S YtkA-like - - - - - - - - - - - - YtkA GDHHQS3_k127_3430627_3 926554.KI912671_gene402 1.068e-129 433.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C GDHHQS3_k127_3430627_11 1033802.SSPSH_003246 8.63e-23 105.0 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG4970 Tfp pilus assembly protein FimT - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl GDHHQS3_k127_3430627_14 314278.NB231_03947 2.101e-17 88.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1WZHE@135613|Chromatiales 135613|Chromatiales NU pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_3430627_15 1122599.AUGR01000024_gene1375 1.274e-15 88.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S7JH@1236|Gammaproteobacteria,1XKGS@135619|Oceanospirillales 135619|Oceanospirillales NU Type IV Pilus-assembly protein W - - - - - - - - - - - - N_methyl,PilW GDHHQS3_k127_3430627_12 314278.NB231_03972 6.567e-22 100.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1WYU2@135613|Chromatiales 135613|Chromatiales NU TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl GDHHQS3_k127_3430627_6 349521.HCH_01257 7.821e-42 161.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XKKS@135619|Oceanospirillales 135619|Oceanospirillales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit GDHHQS3_k127_3430627_5 1244869.H261_13384 1.217e-45 169.0 2CRRJ@1|root,32SPH@2|Bacteria,1NYMT@1224|Proteobacteria,2UTVD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3307) - - - - - - - - - - - - DUF3307 GDHHQS3_k127_3430627_16 1249627.D779_3722 1.759e-13 73.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,1WWSI@135613|Chromatiales 135613|Chromatiales L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 GDHHQS3_k127_3432596_2 1122182.KB903814_gene2961 2.627e-48 181.0 COG0122@1|root,COG0122@2|Bacteria,2HGAB@201174|Actinobacteria,4DIJN@85008|Micromonosporales 201174|Actinobacteria L endonuclease III - - - - - - - - - - - - HhH-GPD GDHHQS3_k127_3432596_5 234831.PSM_A1961 0.0008164 48.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,2Q2K7@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 GDHHQS3_k127_3432596_3 1207063.P24_15831 3.643e-42 168.0 2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,2U9KT@28211|Alphaproteobacteria,2JSXH@204441|Rhodospirillales 204441|Rhodospirillales S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 GDHHQS3_k127_3432596_0 1123073.KB899242_gene1476 4.404e-158 519.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1X4RC@135614|Xanthomonadales 135614|Xanthomonadales N transport system involved in gliding motility, auxiliary component - - - - - - - - - - - - ABC_transp_aux GDHHQS3_k127_3432596_1 1123073.KB899242_gene1477 1.731e-112 370.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales 135614|Xanthomonadales S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 GDHHQS3_k127_3432596_4 83406.HDN1F_28530 3.624e-10 63.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_3440740_7 631362.Thi970DRAFT_03892 4.248e-12 75.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1WYPZ@135613|Chromatiales 135613|Chromatiales P PFAM Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P GDHHQS3_k127_3440740_6 765910.MARPU_08560 8.466e-33 137.0 COG2067@1|root,COG2067@2|Bacteria,1RDE4@1224|Proteobacteria,1SCXR@1236|Gammaproteobacteria 1236|Gammaproteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - GDHHQS3_k127_3440740_0 1454004.AW11_03580 3.269e-124 413.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2VHA3@28216|Betaproteobacteria 28216|Betaproteobacteria S Phospholipase, patatin family - - - ko:K07001 - - - - ko00000 - - - Patatin GDHHQS3_k127_3440740_4 550540.Fbal_3608 4.858e-49 183.0 2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria,1S7CH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 GDHHQS3_k127_3440740_3 1246484.D479_12413 2.348e-50 197.0 COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HEAJ@91061|Bacilli,3NFYA@45667|Halobacillus 91061|Bacilli S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 GDHHQS3_k127_3440740_1 859657.RPSI07_1075 1.599e-67 244.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,1K1P1@119060|Burkholderiaceae 28216|Betaproteobacteria P Periplasmic binding protein btuF - - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - - Peripla_BP_2 GDHHQS3_k127_3440740_5 1121015.N789_13745 5.385e-42 166.0 COG3725@1|root,COG3725@2|Bacteria,1MYFA@1224|Proteobacteria,1SE2J@1236|Gammaproteobacteria,1X4YH@135614|Xanthomonadales 135614|Xanthomonadales V Membrane protein required for beta-lactamase induction ampE - - ko:K03807 - - - - ko00000 - - - CobD_Cbib GDHHQS3_k127_3440740_2 1163408.UU9_13553 5.069e-65 228.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1X4JM@135614|Xanthomonadales 135614|Xanthomonadales L nadh pyrophosphatase nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase GDHHQS3_k127_3451497_6 89462.XP_006051536.1 0.0004424 45.0 KOG3656@1|root,KOG3656@2759|Eukaryota,38HSJ@33154|Opisthokonta,3BJJJ@33208|Metazoa,3D396@33213|Bilateria,4881V@7711|Chordata,491S4@7742|Vertebrata,3J2RE@40674|Mammalia,4J8SB@91561|Cetartiodactyla 33208|Metazoa S Lymphocyte-specific protein 1 LSP1 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0006915,GO:0006935,GO:0006950,GO:0006952,GO:0006968,GO:0006996,GO:0007010,GO:0008092,GO:0008150,GO:0008219,GO:0009605,GO:0009987,GO:0012501,GO:0015629,GO:0016020,GO:0016043,GO:0040011,GO:0042221,GO:0042330,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0050896,GO:0071840,GO:0071944 - ko:K14957 ko05152,map05152 - - - ko00000,ko00001 - - - Caldesmon GDHHQS3_k127_3451497_4 394221.Mmar10_0334 2.069e-92 323.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_3451497_3 1123057.P872_08575 4.924e-104 357.0 COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia 976|Bacteroidetes E Amino acid permease - - - ko:K03294,ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 GDHHQS3_k127_3451497_1 1280950.HJO_00770 1.371e-122 419.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_3451497_0 1280950.HJO_00770 2.495e-123 421.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_3451497_2 566466.NOR53_477 3.387e-111 386.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_3451497_5 1122604.JONR01000004_gene852 3.284e-05 48.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales 135614|Xanthomonadales S Adenylate cyclase - - - - - - - - - - - - TPR_16 GDHHQS3_k127_3459410_3 324925.Ppha_0411 1.067e-46 177.0 2B73M@1|root,3204M@2|Bacteria 2|Bacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_21,Methyltransf_22 GDHHQS3_k127_3459410_4 1121875.KB907547_gene3110 1.9e-19 93.0 COG4313@1|root,COG4313@2|Bacteria,4NS24@976|Bacteroidetes,1I03V@117743|Flavobacteriia 976|Bacteroidetes C Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg GDHHQS3_k127_3459410_1 1122137.AQXF01000002_gene562 2.153e-76 264.0 COG3658@1|root,COG3658@2|Bacteria 2|Bacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - DHC,Ni_hydr_CYTB GDHHQS3_k127_3459410_0 1120953.AUBH01000002_gene1524 1.194e-101 347.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RQJX@1236|Gammaproteobacteria,464B6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - DUF1298,WES_acyltransf GDHHQS3_k127_3459410_2 502025.Hoch_6599 1.121e-70 248.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales 28221|Deltaproteobacteria E Prephenate dehydrogenase chorismate mutase - - 1.3.1.12 ko:K00210 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH GDHHQS3_k127_3460579_6 1157490.EL26_20550 8.164e-22 109.0 COG3919@1|root,COG3919@2|Bacteria,1TR1E@1239|Firmicutes 1239|Firmicutes S ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3,CPSase_L_D2 GDHHQS3_k127_3460579_0 1134413.ANNK01000087_gene279 3.708e-123 412.0 COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA GDHHQS3_k127_3460579_5 333138.LQ50_20125 1.689e-28 128.0 COG3181@1|root,COG3181@2|Bacteria 2|Bacteria E Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC GDHHQS3_k127_3460579_2 880072.Desac_1199 1.826e-54 216.0 COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions,2X8I9@28221|Deltaproteobacteria 28221|Deltaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_3460579_3 1144310.PMI07_006025 4.27e-44 174.0 COG0667@1|root,COG0667@2|Bacteria,1PPQF@1224|Proteobacteria,2V25N@28211|Alphaproteobacteria,4BIT2@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red GDHHQS3_k127_3460579_1 247634.GPB2148_3131 7.685e-75 263.0 COG2021@1|root,COG3509@1|root,COG2021@2|Bacteria,COG3509@2|Bacteria,1PPZW@1224|Proteobacteria,1TH7N@1236|Gammaproteobacteria,1JASD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E alpha/beta hydrolase fold - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 GDHHQS3_k127_3460579_4 570952.ATVH01000017_gene1822 4.245e-36 139.0 COG2801@1|root,COG2801@2|Bacteria,1NAXT@1224|Proteobacteria,2UVUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - - GDHHQS3_k127_3460706_1 1384056.N787_06225 1.665e-77 262.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,1X4IZ@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 GDHHQS3_k127_3460706_2 287.DR97_4856 1.736e-71 255.0 COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria,1YEE8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR GDHHQS3_k127_3460706_0 1123253.AUBD01000009_gene2350 3.01e-270 855.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1X5AZ@135614|Xanthomonadales 135614|Xanthomonadales S MMPL family - - - - - - - - - - - - MMPL GDHHQS3_k127_3461083_5 871585.BDGL_001346 3.023e-14 75.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,3NIQU@468|Moraxellaceae 1236|Gammaproteobacteria G Organic Anion Transporter Polypeptide (OATP) family - - - - - - - - - - - - MFS_1 GDHHQS3_k127_3461083_6 211165.AJLN01000056_gene2884 1.632e-09 68.0 COG2197@1|root,COG2197@2|Bacteria,1G22Y@1117|Cyanobacteria,1JGRX@1189|Stigonemataceae 1117|Cyanobacteria KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GAF,GerE GDHHQS3_k127_3461083_2 1353531.AZNX01000039_gene5951 4.135e-157 504.0 COG5485@1|root,COG5485@2|Bacteria,1MXSP@1224|Proteobacteria,2TVPC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Haem-containing dehydratase - - 4.99.1.5 ko:K13028 - - R02827 RC00791 ko00000,ko01000 - - - Dehydratase_hem GDHHQS3_k127_3461083_0 420662.Mpe_A0993 1.827e-166 529.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2VM10@28216|Betaproteobacteria 28216|Betaproteobacteria S Carbon-nitrogen hydrolase - - 3.5.5.7 ko:K01502 ko00643,ko01120,map00643,map01120 - R05358 RC01336 ko00000,ko00001,ko01000 - - - CN_hydrolase GDHHQS3_k127_3461083_1 1219035.NT2_07_01850 6.131e-158 529.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2U30T@28211|Alphaproteobacteria,2K228@204457|Sphingomonadales 204457|Sphingomonadales M TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_3461083_3 756499.Desde_0320 1.558e-155 498.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,260HN@186807|Peptococcaceae 186801|Clostridia S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase GDHHQS3_k127_3461083_4 1173024.KI912148_gene4124 6.561e-28 117.0 COG0388@1|root,COG0388@2|Bacteria,1G1UJ@1117|Cyanobacteria 1117|Cyanobacteria S nitrilase - - 3.5.5.1,3.5.5.7 ko:K01501,ko:K01502 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05358,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC01336,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase GDHHQS3_k127_3468120_7 686340.Metal_0082 1.017e-23 113.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria,1XFCG@135618|Methylococcales 135618|Methylococcales C PFAM Cytochrome C - - - - - - - - - - - - Cytochrome_CBB3 GDHHQS3_k127_3468120_8 1121935.AQXX01000143_gene4197 3.952e-17 93.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_3468120_5 1116472.MGMO_147c00110 1.331e-48 184.0 293CN@1|root,2Z9VJ@2|Bacteria,1MXNG@1224|Proteobacteria,1RZCQ@1236|Gammaproteobacteria,1XDMH@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - GDHHQS3_k127_3468120_9 930169.B5T_04287 4.545e-13 73.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_3468120_6 1535422.ND16A_2692 1.929e-34 149.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome c cc4 - - - - - - - - - - - Cytochrom_C GDHHQS3_k127_3468120_1 1397527.Q670_06160 2.059e-134 443.0 COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,1RSDG@1236|Gammaproteobacteria,1XNVN@135619|Oceanospirillales 135619|Oceanospirillales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - DUF3336,Patatin GDHHQS3_k127_3468120_0 338966.Ppro_2773 9.63e-136 443.0 COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria 28221|Deltaproteobacteria K acetyltransferase - - - - - - - - - - - - - GDHHQS3_k127_3468120_4 338966.Ppro_2772 4.664e-49 189.0 COG0746@1|root,COG0746@2|Bacteria,1QWF1@1224|Proteobacteria 1224|Proteobacteria H MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 GDHHQS3_k127_3468120_3 1283300.ATXB01000001_gene1373 4.576e-75 262.0 COG4424@1|root,COG4424@2|Bacteria,1RGI6@1224|Proteobacteria,1S85X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_1,Sulfotransfer_3 GDHHQS3_k127_3468120_2 331678.Cphamn1_1855 2.977e-125 421.0 COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi 1090|Chlorobi C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 GDHHQS3_k127_3488221_0 1121374.KB891591_gene3471 1.505e-131 427.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR GDHHQS3_k127_3488221_1 713587.THITH_13175 3.186e-61 214.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales 135613|Chromatiales O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB GDHHQS3_k127_3488221_2 312309.VF_2001 1.492e-37 145.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1XWWV@135623|Vibrionales 135623|Vibrionales I oligoketide cyclase lipid transport protein ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc GDHHQS3_k127_3488221_5 1158762.KB898047_gene576 2.217e-21 98.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ6P@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH GDHHQS3_k127_3488221_4 1500890.JQNL01000001_gene397 1.167e-21 105.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1X6JC@135614|Xanthomonadales 135614|Xanthomonadales J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA GDHHQS3_k127_3488221_3 1121013.P873_00190 1.096e-27 113.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1X6F1@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR GDHHQS3_k127_3507962_9 649638.Trad_0190 2.121e-49 179.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1WMCG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C GDHHQS3_k127_3507962_5 1121013.P873_03695 8.52e-80 276.0 COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,1S2WV@1236|Gammaproteobacteria,1X3F1@135614|Xanthomonadales 135614|Xanthomonadales EG EamA-like transporter family - - - ko:K15268 - - - - ko00000,ko02000 2.A.7.3.2 - - EamA GDHHQS3_k127_3507962_10 76114.ebA3896 3.625e-42 166.0 COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 GDHHQS3_k127_3507962_1 502025.Hoch_5031 2.654e-137 460.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,438DH@68525|delta/epsilon subdivisions,2WXQW@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - Exo_endo_phos GDHHQS3_k127_3507962_8 1121440.AUMA01000003_gene3007 3.989e-51 195.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,42RJH@68525|delta/epsilon subdivisions,2WP0R@28221|Deltaproteobacteria,2M8CZ@213115|Desulfovibrionales 28221|Deltaproteobacteria G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase GDHHQS3_k127_3507962_12 1219035.NT2_06_04400 7.233e-12 68.0 2EHHF@1|root,33B9C@2|Bacteria,1N3NN@1224|Proteobacteria,2UC59@28211|Alphaproteobacteria,2K6MT@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_3507962_0 1278307.KB907015_gene3524 1.183e-211 672.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,2QIUB@267894|Psychromonadaceae 1236|Gammaproteobacteria V ABC transporter transmembrane region draA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GDHHQS3_k127_3507962_3 318161.Sden_3305 4.023e-105 349.0 2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3507962_6 1502851.FG93_06077 6.72e-55 204.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,3JRK1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2 GDHHQS3_k127_3507962_4 566466.NOR53_3405 1.202e-99 335.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1J643@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 GDHHQS3_k127_3507962_13 84531.JMTZ01000020_gene3704 1.849e-11 72.0 2ANYG@1|root,2ZGFF@2|Bacteria,1QEQI@1224|Proteobacteria,1TBIU@1236|Gammaproteobacteria,1X94U@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_3507962_2 617140.AJZE01000039_gene2291 1.893e-115 384.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,1XW2T@135623|Vibrionales 135623|Vibrionales FL Metal binding domain of Ada - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18 GDHHQS3_k127_3507962_7 452637.Oter_0989 1.998e-53 200.0 COG4783@1|root,COG4783@2|Bacteria 2|Bacteria L chaperone-mediated protein folding - - - - - - - - - - - - Peptidase_M48 GDHHQS3_k127_3507962_11 452637.Oter_0990 9.304e-32 132.0 2EKQ4@1|root,33EDV@2|Bacteria 2|Bacteria S Bacterial SH3 domain homologues - - - - - - - - - - - - SH3_3 GDHHQS3_k127_3507962_14 1197906.CAJQ02000023_gene2215 0.0001312 47.0 COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TS3S@28211|Alphaproteobacteria,3JS4X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP GDHHQS3_k127_3512793_1 1298593.TOL_0809 2.211e-27 113.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XIFQ@135619|Oceanospirillales 135619|Oceanospirillales M peptidase - - - - - - - - - - - - Peptidase_M23 GDHHQS3_k127_3512793_0 472759.Nhal_0500 0.0 1152.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW GDHHQS3_k127_3515086_1 745014.OMB55_00002470 9.534e-66 239.0 COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,1SB13@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR GDHHQS3_k127_3515086_0 1192868.CAIU01000016_gene2144 4.473e-120 396.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2U3SA@28211|Alphaproteobacteria,43JJ9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P PFAM Rieske 2Fe-2S - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A GDHHQS3_k127_3532857_12 1121013.P873_03985 4.052e-38 144.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P GDHHQS3_k127_3532857_8 243365.CV_3399 5.043e-73 249.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2VPZP@28216|Betaproteobacteria,2KQW5@206351|Neisseriales 206351|Neisseriales P Iron-storage protein bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin GDHHQS3_k127_3532857_13 768066.HELO_1362 3.415e-11 66.0 COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria,1SGGM@1236|Gammaproteobacteria,1XMP1@135619|Oceanospirillales 135619|Oceanospirillales P Bacterioferritin-associated ferredoxin bfd - - ko:K02192 - - - - ko00000 - - - Fer2_BFD GDHHQS3_k127_3532857_2 342610.Patl_3109 6.842e-226 723.0 COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,2Q13H@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P COG4772 Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_3532857_9 1094184.KWO_0121580 2.238e-72 248.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,1X38R@135614|Xanthomonadales 135614|Xanthomonadales F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX GDHHQS3_k127_3532857_6 521719.ATXQ01000013_gene203 5.011e-97 327.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1YDHA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD GDHHQS3_k127_3532857_10 1178482.BJB45_14365 9.376e-64 227.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RQ6C@1236|Gammaproteobacteria 1236|Gammaproteobacteria HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran GDHHQS3_k127_3532857_5 1232410.KI421421_gene3631 1.857e-99 339.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC GDHHQS3_k127_3532857_11 1535422.ND16A_1248 8.707e-63 229.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,1RQTS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_3,HlyD_D23 GDHHQS3_k127_3532857_0 1535422.ND16A_1247 0.0 1078.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_3532857_3 1300345.LF41_2027 6.407e-203 643.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1X3AK@135614|Xanthomonadales 135614|Xanthomonadales E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_3532857_4 713586.KB900536_gene567 4.436e-190 614.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales 135613|Chromatiales O PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 GDHHQS3_k127_3532857_7 765913.ThidrDRAFT_0724 8.286e-80 270.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1WWRQ@135613|Chromatiales 135613|Chromatiales S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA GDHHQS3_k127_3532857_1 519989.ECTPHS_00235 6.106e-253 792.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1WW7Z@135613|Chromatiales 135613|Chromatiales J TIGRFAM glutaminyl-tRNA synthetase glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C GDHHQS3_k127_3536003_2 671143.DAMO_3069 6.14e-43 160.0 COG0156@1|root,COG0156@2|Bacteria,2NNMX@2323|unclassified Bacteria 2|Bacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.29,2.3.1.47,2.3.1.50 ko:K00639,ko:K00652,ko:K00654 ko00260,ko00600,ko00780,ko01100,ko04071,ko04138,map00260,map00600,map00780,map01100,map04071,map04138 M00094,M00099,M00123,M00573,M00577 R00371,R01281,R03210,R10124 RC00004,RC00039,RC00394,RC02725,RC02849 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_3536003_0 1283300.ATXB01000001_gene564 1.021e-67 246.0 COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,1RMK6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Polysaccharide biosynthesis protein yghQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 GDHHQS3_k127_3536003_1 1121405.dsmv_2095 5.656e-47 175.0 COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria 1224|Proteobacteria I lipid kinase activity - - - - - - - - - - - - Mmp37 GDHHQS3_k127_3543957_2 1395571.TMS3_0108230 1.665e-110 362.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.54,1.2.1.99 ko:K09472,ko:K12254 ko00330,ko01100,map00330,map01100 M00136 R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_3543957_4 1380394.JADL01000010_gene4401 6.492e-69 245.0 COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,2JW6C@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 GDHHQS3_k127_3543957_1 247634.GPB2148_1644 2.41e-125 420.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1J8P3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C GDHHQS3_k127_3543957_0 247490.KSU1_C1110 4.988e-129 424.0 COG5008@1|root,COG5008@2|Bacteria,2J2NM@203682|Planctomycetes 203682|Planctomycetes NU Type II/IV secretion system protein - - - - - - - - - - - - T2SSE GDHHQS3_k127_3543957_7 1255043.TVNIR_0908 2.972e-39 149.0 COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria,1WZDP@135613|Chromatiales 135613|Chromatiales S PFAM Plasmid maintenance system killer - - - ko:K07334 - - - - ko00000,ko02048 - - - HigB-like_toxin GDHHQS3_k127_3543957_6 667632.KB890165_gene2460 3.297e-41 153.0 COG3093@1|root,COG3093@2|Bacteria,1N2TD@1224|Proteobacteria,2WFU8@28216|Betaproteobacteria,1KI64@119060|Burkholderiaceae 28216|Betaproteobacteria K TIGRFAM Addiction module antidote protein, HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_3543957_3 382464.ABSI01000012_gene2216 9.474e-105 350.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,46XK4@74201|Verrucomicrobia,2IW45@203494|Verrucomicrobiae 203494|Verrucomicrobiae L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 GDHHQS3_k127_3543957_5 580332.Slit_2475 3.825e-55 195.0 COG4634@1|root,COG4634@2|Bacteria,1NAN6@1224|Proteobacteria,2VVRB@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3543957_8 580332.Slit_2476 3.53e-35 135.0 COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,2VWIS@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 GDHHQS3_k127_3561603_5 1163408.UU9_13296 2.885e-28 119.0 28I3N@1|root,2Z87C@2|Bacteria,1R8BJ@1224|Proteobacteria,1S1F3@1236|Gammaproteobacteria,1X2XC@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 GDHHQS3_k127_3561603_3 935863.AWZR01000007_gene311 1.601e-87 297.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1X3M9@135614|Xanthomonadales 135614|Xanthomonadales P Transporter corC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC GDHHQS3_k127_3561603_4 1027273.GZ77_21695 4.435e-46 172.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XJZW@135619|Oceanospirillales 135619|Oceanospirillales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 GDHHQS3_k127_3561603_2 1283300.ATXB01000001_gene504 3.63e-128 417.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XE38@135618|Methylococcales 135618|Methylococcales T PFAM PhoH-like protein - - - ko:K06217 - - - - ko00000 - - - PhoH GDHHQS3_k127_3561603_0 396588.Tgr7_2292 6.548e-209 657.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 GDHHQS3_k127_3561603_1 1123253.AUBD01000007_gene699 6.113e-160 508.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1X49B@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GDHHQS3_k127_3563304_0 76114.ebA4954 1.811e-200 630.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNN@28216|Betaproteobacteria,2KVWA@206389|Rhodocyclales 206389|Rhodocyclales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh GDHHQS3_k127_3563304_1 1123368.AUIS01000008_gene2155 2.114e-67 246.0 COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,1T4ST@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the heme-copper respiratory oxidase family - - - - - - - - - - - - - GDHHQS3_k127_3563304_2 1123368.AUIS01000008_gene2154 2.223e-09 60.0 COG0425@1|root,COG0425@2|Bacteria,1QU8C@1224|Proteobacteria,1T5JF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249 GDHHQS3_k127_3567520_6 748247.AZKH_p0448 1.68e-13 71.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,2KW21@206389|Rhodocyclales 206389|Rhodocyclales S VIT family - - - - - - - - - - - - VIT1 GDHHQS3_k127_3567520_4 396588.Tgr7_0507 1.374e-28 115.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GDHHQS3_k127_3567520_5 697282.Mettu_3285 2.994e-23 103.0 COG0724@1|root,COG0724@2|Bacteria,1NDEM@1224|Proteobacteria,1SFDX@1236|Gammaproteobacteria,1XFGC@135618|Methylococcales 135618|Methylococcales S PFAM RNA recognition motif - - - - - - - - - - - - RRM_1 GDHHQS3_k127_3567520_2 522306.CAP2UW1_2786 2.333e-78 279.0 COG3064@1|root,COG4969@1|root,COG3064@2|Bacteria,COG4969@2|Bacteria,1MXPS@1224|Proteobacteria,2VKTY@28216|Betaproteobacteria,1KQQJ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Protein of unknown function (DUF3300) - - - - - - - - - - - - DUF3300 GDHHQS3_k127_3567520_3 909663.KI867150_gene2891 1.872e-69 246.0 COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales 28221|Deltaproteobacteria N Protein of unknown function (DUF2950) - - - - - - - - - - - - DUF2950 GDHHQS3_k127_3567520_0 1049564.TevJSym_ac00480 1.132e-199 629.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C GDHHQS3_k127_3567520_1 523791.Kkor_0209 1.319e-193 621.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C GDHHQS3_k127_3572838_0 76114.ebA5393 2.21e-279 863.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family padB - 1.17.5.1,3.1.2.25 ko:K18361 ko00360,map00360 - R07222,R07294 RC00004,RC01844,RC01903 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding GDHHQS3_k127_3572838_1 76114.ebA5390 4.47e-149 477.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,2VP5N@28216|Betaproteobacteria,2KVFG@206389|Rhodocyclales 206389|Rhodocyclales K PaaX family padR - - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C GDHHQS3_k127_3572838_2 76114.ebA5403 1.973e-30 125.0 COG1042@1|root,COG1042@2|Bacteria,1NU6B@1224|Proteobacteria,2VPMK@28216|Betaproteobacteria,2KVD5@206389|Rhodocyclales 206389|Rhodocyclales C CoA binding domain - - - - - - - - - - - - CoA_binding_2,Succ_CoA_lig GDHHQS3_k127_3574436_0 1117647.M5M_15680 0.0 1218.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J4WC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_3574436_3 425104.Ssed_1612 7.688e-18 88.0 COG0607@1|root,COG0607@2|Bacteria,1RHVM@1224|Proteobacteria,1SD9C@1236|Gammaproteobacteria,2QCHJ@267890|Shewanellaceae 1236|Gammaproteobacteria P PFAM Rhodanese domain protein pspE GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K03972 - - - - ko00000 - - iE2348C_1286.E2348C_1500,iECABU_c1320.ECABU_c15910,iSDY_1059.SDY_1936,ic_1306.c1779 Rhodanese GDHHQS3_k127_3574436_2 648757.Rvan_2520 1.056e-24 108.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,3N8YG@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 GDHHQS3_k127_3574436_1 566466.NOR53_3227 3.129e-139 455.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1J804@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X GDHHQS3_k127_3586284_1 1234364.AMSF01000015_gene3226 7.407e-142 457.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1X4RS@135614|Xanthomonadales 135614|Xanthomonadales IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB GDHHQS3_k127_3586284_3 247634.GPB2148_1352 2.222e-49 184.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 GDHHQS3_k127_3586284_0 472759.Nhal_0903 0.0 1202.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS GDHHQS3_k127_3586284_2 1123073.KB899241_gene1833 6.18e-81 280.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1X3EA@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase GDHHQS3_k127_3586284_4 1298593.TOL_2881 3.18e-25 109.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XH8T@135619|Oceanospirillales 135619|Oceanospirillales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN GDHHQS3_k127_3589532_1 396588.Tgr7_1407 2.298e-167 543.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1WXN2@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H GDHHQS3_k127_3589532_10 666685.R2APBS1_3164 5.315e-20 96.0 COG0457@1|root,COG0457@2|Bacteria,1N3T7@1224|Proteobacteria,1T1KY@1236|Gammaproteobacteria,1X75P@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 GDHHQS3_k127_3589532_0 1123073.KB899243_gene826 3.344e-214 683.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1X3ZE@135614|Xanthomonadales 135614|Xanthomonadales KL Helicase yoaA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,ResIII GDHHQS3_k127_3589532_7 754436.JCM19237_504 7.241e-35 143.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1XTAV@135623|Vibrionales 135623|Vibrionales O COG1214 Inactive homolog of metal-dependent proteases tsaB - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 GDHHQS3_k127_3589532_2 1049564.TevJSym_ak00740 2.79e-139 462.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1JC0Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C GDHHQS3_k127_3589532_9 391038.Bphy_0261 9.343e-24 105.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,1K8I2@119060|Burkholderiaceae 28216|Betaproteobacteria G phosphocarrier, HPr family ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr GDHHQS3_k127_3589532_12 1415780.JPOG01000001_gene473 1.153e-17 88.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1XD2Z@135614|Xanthomonadales 135614|Xanthomonadales G Phosphotransferase system, mannose fructose-specific component IIA - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man GDHHQS3_k127_3589532_5 767434.Fraau_1262 2.829e-84 288.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1X3TG@135614|Xanthomonadales 135614|Xanthomonadales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 GDHHQS3_k127_3589532_4 913325.N799_01930 4.899e-100 338.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S2K0@1236|Gammaproteobacteria,1X321@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N GDHHQS3_k127_3589532_6 472759.Nhal_0332 6.321e-40 153.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1WYAA@135613|Chromatiales 135613|Chromatiales G PTS IIA-like nitrogen-regulatory protein PtsN - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 GDHHQS3_k127_3589532_8 396588.Tgr7_0725 3.848e-34 135.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales 135613|Chromatiales J Sigma 54 modulation protein - - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE GDHHQS3_k127_3589532_3 713587.THITH_14660 1.197e-117 395.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1WVZD@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD GDHHQS3_k127_3589532_11 935863.AWZR01000004_gene720 2.319e-19 87.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1X31A@135614|Xanthomonadales 135614|Xanthomonadales S abc transporter atp-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C GDHHQS3_k127_3612795_3 1234364.AMSF01000095_gene2585 6.195e-32 132.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1X3ZW@135614|Xanthomonadales 135614|Xanthomonadales S overlaps another CDS with the same product name - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ GDHHQS3_k127_3612795_4 686340.Metal_3725 5.226e-26 113.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XFBI@135618|Methylococcales 135618|Methylococcales S RDD family - - - - - - - - - - - - RDD GDHHQS3_k127_3612795_1 1137799.GZ78_18090 4.54e-55 204.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1XK5S@135619|Oceanospirillales 135619|Oceanospirillales D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 GDHHQS3_k127_3612795_0 414684.RC1_0800 5.44e-110 371.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,2TU50@28211|Alphaproteobacteria,2JSBB@204441|Rhodospirillales 204441|Rhodospirillales U MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB GDHHQS3_k127_3612795_2 1122137.AQXF01000001_gene2819 1.954e-53 196.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,2UAB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria U TonB system transport protein ExbB - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB GDHHQS3_k127_36149_4 414684.RC1_1459 9.411e-112 368.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JPVQ@204441|Rhodospirillales 204441|Rhodospirillales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 GDHHQS3_k127_36149_3 247634.GPB2148_1766 1.725e-119 397.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1J4HX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 GDHHQS3_k127_36149_1 247634.GPB2148_1766 2.369e-127 416.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1J4HX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 GDHHQS3_k127_36149_0 1122135.KB893134_gene3128 6.955e-154 498.0 COG1960@1|root,COG1960@2|Bacteria,1MUTN@1224|Proteobacteria,2U38F@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_36149_5 935261.JAGL01000019_gene597 8.509e-58 209.0 COG1309@1|root,COG1309@2|Bacteria,1RDM7@1224|Proteobacteria,2U83S@28211|Alphaproteobacteria,43HPZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K BetI-type transcriptional repressor, C-terminal - - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N GDHHQS3_k127_36149_2 1122135.KB893134_gene3130 4.577e-124 402.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,CTP_transf_3 GDHHQS3_k127_3624491_1 1344012.ATMI01000003_gene992 3.713e-192 611.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,4BUEX@82986|Tatumella 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c GDHHQS3_k127_3624491_2 768671.ThimaDRAFT_1585 3.117e-86 295.0 COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,1RYHJ@1236|Gammaproteobacteria,1WXZG@135613|Chromatiales 135613|Chromatiales K WYL domain - - - - - - - - - - - - HTH_11,WYL GDHHQS3_k127_3624491_0 1234364.AMSF01000082_gene2992 8.89e-199 632.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1X4AB@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - - - - - - - - - - - Aminotran_3 GDHHQS3_k127_3624491_3 1419583.V466_06595 2.578e-06 49.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1YP5K@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 GDHHQS3_k127_3625469_1 243160.BMA0733 2.723e-139 454.0 COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2VHF2@28216|Betaproteobacteria,1K0JD@119060|Burkholderiaceae 28216|Betaproteobacteria G PFAM major facilitator superfamily MFS_1 rhmT_2 - - - - - - - - - - - MFS_1 GDHHQS3_k127_3625469_11 1334046.AYTB01000015_gene1649 3.236e-07 58.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,26E9V@186818|Planococcaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH GDHHQS3_k127_3625469_6 675635.Psed_0101 3.538e-29 121.0 COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E0R9@85010|Pseudonocardiales 201174|Actinobacteria S protein involved in propionate catabolism - - - - - - - - - - - - MmgE_PrpD GDHHQS3_k127_3625469_7 1380391.JIAS01000013_gene3446 1.704e-26 118.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD GDHHQS3_k127_3625469_5 1123290.AUDQ01000030_gene3045 2.535e-59 220.0 COG1638@1|root,COG1638@2|Bacteria 2|Bacteria G carbohydrate transport - - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP GDHHQS3_k127_3625469_9 1238450.VIBNISOn1_830143 1.05e-22 104.0 COG3090@1|root,COG3090@2|Bacteria,1NDAE@1224|Proteobacteria,1T5R5@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ GDHHQS3_k127_3625469_2 1123290.AUDQ01000030_gene3046 2.191e-135 443.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4HE36@91061|Bacilli 91061|Bacilli G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM GDHHQS3_k127_3625469_12 644076.SCH4B_0664 4.48e-06 58.0 COG1802@1|root,COG1802@2|Bacteria,1MW9G@1224|Proteobacteria,2TVAR@28211|Alphaproteobacteria,4NCK9@97050|Ruegeria 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR GDHHQS3_k127_3625469_4 1123023.JIAI01000023_gene4286 1.87e-77 271.0 COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E0K0@85010|Pseudonocardiales 201174|Actinobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B GDHHQS3_k127_3625469_8 469383.Cwoe_4138 4.563e-23 102.0 COG2141@1|root,COG2141@2|Bacteria,2ID60@201174|Actinobacteria,4CTIG@84995|Rubrobacteria 84995|Rubrobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase GDHHQS3_k127_3625469_13 1122194.AUHU01000004_gene1332 0.0001742 47.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RS91@1236|Gammaproteobacteria,4663Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_3625469_0 1230476.C207_02619 3e-183 593.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6,4.1.1.7 ko:K01576,ko:K01652 ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00595,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_3625469_10 392499.Swit_1527 1.772e-15 83.0 COG2010@1|root,COG2010@2|Bacteria,1NK3D@1224|Proteobacteria,2UN55@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 GDHHQS3_k127_3625469_3 1265313.HRUBRA_00384 7.975e-130 428.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J57E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_3634543_2 247634.GPB2148_793 2.315e-110 365.0 COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,1RQBF@1236|Gammaproteobacteria,1J62W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S11 family pbpG GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07262 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S11 GDHHQS3_k127_3634543_1 498211.CJA_2201 1.217e-111 370.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1FG8A@10|Cellvibrio 1236|Gammaproteobacteria S Rhodanese Homology Domain yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C GDHHQS3_k127_3634543_0 1123519.PSJM300_01780 1.152e-131 429.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1Z0UX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria U Transport permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane GDHHQS3_k127_3634543_3 1449049.JONW01000005_gene1466 3.842e-59 207.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2KFAS@204458|Caulobacterales 204458|Caulobacterales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_3636779_7 1300345.LF41_487 4.367e-54 191.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1X30J@135614|Xanthomonadales 135614|Xanthomonadales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 GDHHQS3_k127_3636779_9 1123073.KB899243_gene732 1.302e-33 133.0 2ANPD@1|root,31DNY@2|Bacteria,1PCJI@1224|Proteobacteria,1SXMI@1236|Gammaproteobacteria,1X6E6@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_3636779_8 857087.Metme_0971 3.459e-50 179.0 COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,1XFTT@135618|Methylococcales 135618|Methylococcales S Evidence 4 Homologs of previously reported genes of - - - ko:K09700 - - - - ko00000 - - - - GDHHQS3_k127_3636779_0 1121935.AQXX01000108_gene413 2.829e-201 630.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1XH2U@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GDHHQS3_k127_3636779_1 1042375.AFPL01000046_gene1979 2.965e-132 426.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,46528@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde fghA - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase GDHHQS3_k127_3636779_10 1027273.GZ77_11445 8.086e-23 109.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1XM8K@135619|Oceanospirillales 135619|Oceanospirillales L Methyltransferase - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 GDHHQS3_k127_3636779_6 1267533.KB906741_gene549 1.823e-54 198.0 COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia 204432|Acidobacteriia S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 GDHHQS3_k127_3636779_5 1123368.AUIS01000004_gene248 6.684e-76 263.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2NBQP@225057|Acidithiobacillales 225057|Acidithiobacillales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase GDHHQS3_k127_3636779_3 1286106.MPL1_04417 1.595e-86 293.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,46025@72273|Thiotrichales 72273|Thiotrichales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P GDHHQS3_k127_3636779_4 1292034.OR37_00750 4.985e-80 276.0 COG0457@1|root,COG4424@1|root,COG0457@2|Bacteria,COG4424@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 GDHHQS3_k127_3636779_2 768671.ThimaDRAFT_0706 9.208e-101 338.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG GDHHQS3_k127_3636779_11 1304275.C41B8_17923 1.036e-14 74.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG GDHHQS3_k127_3654584_3 379066.GAU_2382 2.862e-132 432.0 COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C GDHHQS3_k127_3654584_7 290340.AAur_4049 0.0001434 55.0 COG0739@1|root,COG5479@1|root,COG5640@1|root,COG0739@2|Bacteria,COG5479@2|Bacteria,COG5640@2|Bacteria,2GN4T@201174|Actinobacteria,1WA90@1268|Micrococcaceae 201174|Actinobacteria MO FG-GAP repeat - - - - - - - - - - - - VCBS GDHHQS3_k127_3654584_6 944481.JAFP01000001_gene1117 6.447e-16 92.0 COG0419@1|root,COG3591@1|root,COG0419@2|Bacteria,COG3591@2|Bacteria,1NG4U@1224|Proteobacteria,43BII@68525|delta/epsilon subdivisions,2X6WW@28221|Deltaproteobacteria,2M6YU@213113|Desulfurellales 28221|Deltaproteobacteria E PAN domain - - - - - - - - - - - - PAN_4,WSC GDHHQS3_k127_3654584_2 2340.JV46_24410 3.355e-193 626.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.89,4.2.2.3 ko:K01224,ko:K01729 ko00051,map00051 - R03706 - ko00000,ko00001,ko01000 - - - Beta_helix,Big_4,Glyco_hydro_53,PKD,SLH GDHHQS3_k127_3654584_4 1244869.H261_21029 1.171e-59 210.0 COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria,2JTDY@204441|Rhodospirillales 204441|Rhodospirillales S Rubrerythrin - - - - - - - - - - - - Rubrerythrin GDHHQS3_k127_3654584_0 1410619.SRDD_19360 3.464e-254 794.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,400PM@613|Serratia 1236|Gammaproteobacteria E converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP asnB GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - iB21_1397.B21_00622,iECBD_1354.ECBD_2988,iECB_1328.ECB_00631,iECD_1391.ECD_00631,iEcHS_1320.EcHS_A0717,iEcolC_1368.EcolC_2982,iSF_1195.SF0619 Asn_synthase,GATase_7 GDHHQS3_k127_3654584_1 506534.Rhein_0386 3.606e-226 726.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1WW7C@135613|Chromatiales 135613|Chromatiales E Belongs to the aspartokinase family - - - - - - - - - - - - AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3 GDHHQS3_k127_3654584_5 223926.28805478 5.315e-51 188.0 COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,1XU46@135623|Vibrionales 135623|Vibrionales F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GDHHQS3_k127_3671504_6 1280941.HY2_13765 6.153e-41 159.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,2U93S@28211|Alphaproteobacteria,43XT0@69657|Hyphomonadaceae 28211|Alphaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB GDHHQS3_k127_3671504_1 402881.Plav_1906 3.636e-139 470.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2TT1Y@28211|Alphaproteobacteria,1JNKQ@119043|Rhodobiaceae 28211|Alphaproteobacteria D G-rich domain on putative tyrosine kinase - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz GDHHQS3_k127_3671504_9 1150626.PHAMO_270226 5.734e-08 63.0 2EAYM@1|root,334ZJ@2|Bacteria,1NE7J@1224|Proteobacteria,2UGV7@28211|Alphaproteobacteria,2JUAK@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - GDHHQS3_k127_3671504_4 1380394.JADL01000002_gene1572 1.792e-72 253.0 COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2JSBR@204441|Rhodospirillales 204441|Rhodospirillales T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos GDHHQS3_k127_3671504_7 717772.THIAE_06015 9.6e-26 122.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG0790 FOG TPR repeat, SEL1 subfamily Z012_10315 - - ko:K07126 - - - - ko00000 - - - Sel1 GDHHQS3_k127_3671504_10 585.DR95_2528 0.0001237 54.0 COG3266@1|root,COG3266@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,3Z2MY@583|Proteus 1236|Gammaproteobacteria D Cell division protein DamX damX GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR GDHHQS3_k127_3671504_3 402881.Plav_1908 4.047e-74 266.0 COG3307@1|root,COG3307@2|Bacteria,1PR67@1224|Proteobacteria,2VCTX@28211|Alphaproteobacteria,1JQF7@119043|Rhodobiaceae 28211|Alphaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C GDHHQS3_k127_3671504_5 1454004.AW11_03536 1.809e-64 234.0 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VIE1@28216|Betaproteobacteria 28216|Betaproteobacteria M Glycosyl transferase, family 4 wecA - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 GDHHQS3_k127_3671504_0 743721.Psesu_3002 2.274e-170 540.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1X3HX@135614|Xanthomonadales 135614|Xanthomonadales GM dehydratase - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd GDHHQS3_k127_3671504_2 1499967.BAYZ01000050_gene2808 2.48e-136 443.0 COG1087@1|root,COG1087@2|Bacteria,2NNVI@2323|unclassified Bacteria 2|Bacteria M NAD(P)H-binding galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd GDHHQS3_k127_3671504_8 2340.JV46_19280 3.233e-12 75.0 2C8KX@1|root,32RMF@2|Bacteria,1N68G@1224|Proteobacteria,1SDSS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised nucleotidyltransferase - - - - - - - - - - - - NTP_transf_5 GDHHQS3_k127_3688744_1 1038860.AXAP01000040_gene2864 2.238e-54 195.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,3JUMX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Na+ dependent nucleoside transporter C-terminus MA20_32460 - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N GDHHQS3_k127_3688744_3 671143.DAMO_2687 5.141e-22 97.0 COG2161@1|root,COG2161@2|Bacteria 2|Bacteria D toxin-antitoxin pair type II binding relF GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 ko:K08591,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 - - - PhdYeFM_antitox GDHHQS3_k127_3688744_2 671143.DAMO_2686 4.685e-22 99.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity relE GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin GDHHQS3_k127_3688744_0 204669.Acid345_2426 3.853e-123 409.0 COG3550@1|root,COG3550@2|Bacteria,3Y5G9@57723|Acidobacteria,2JJW5@204432|Acidobacteriia 204432|Acidobacteriia S Pfam:HipA_N - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C GDHHQS3_k127_3688744_4 1298593.TOL_2045 8.573e-09 63.0 COG1396@1|root,COG1396@2|Bacteria,1QUPK@1224|Proteobacteria,1T4CG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 GDHHQS3_k127_3727537_6 314270.RB2083_2846 1.842e-09 60.0 COG2801@1|root,COG2801@2|Bacteria,1NYK4@1224|Proteobacteria,2UTDW@28211|Alphaproteobacteria,3ZIHF@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - - GDHHQS3_k127_3727537_2 247634.GPB2148_14 4.693e-25 107.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria 1224|Proteobacteria L Transposase and inactivated derivatives - - 2.7.7.49 ko:K00986,ko:K07497 - - - - ko00000,ko01000 - - - HTH_32,rve,rve_3 GDHHQS3_k127_3727537_0 247634.GPB2148_14 2.031e-64 228.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria 1224|Proteobacteria L Transposase and inactivated derivatives - - 2.7.7.49 ko:K00986,ko:K07497 - - - - ko00000,ko01000 - - - HTH_32,rve,rve_3 GDHHQS3_k127_3727537_4 1123247.AUIJ01000043_gene802 1.264e-15 78.0 COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2963 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_Tnp_1 GDHHQS3_k127_3727537_5 864069.MicloDRAFT_00051360 2.981e-10 64.0 COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria,1JVFR@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GDHHQS3_k127_3727537_3 1034807.FBFL15_0657 3.14e-16 89.0 28PPK@1|root,2ZCC0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3727537_1 864702.OsccyDRAFT_2878 2.419e-54 215.0 COG2114@1|root,COG2114@2|Bacteria,1G53R@1117|Cyanobacteria,1HFDP@1150|Oscillatoriales 1117|Cyanobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc GDHHQS3_k127_3728268_1 565045.NOR51B_3 1.143e-108 363.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,1JA4W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 GDHHQS3_k127_3728268_0 1121374.KB891589_gene44 9.02e-145 493.0 COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,1SM3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_3735427_1 1458427.BAWN01000013_gene920 1.895e-128 424.0 COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,2VQ1T@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4143) - - - - - - - - - - - - AAA_14,DUF4143 GDHHQS3_k127_3735427_2 1123256.KB907941_gene123 2.528e-120 393.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1X54Q@135614|Xanthomonadales 135614|Xanthomonadales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GDHHQS3_k127_3735427_3 1123256.KB907941_gene125 3.135e-44 164.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,1X7J3@135614|Xanthomonadales 135614|Xanthomonadales S PFAM DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX GDHHQS3_k127_3735427_0 1415779.JOMH01000001_gene494 2.528e-130 422.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1X33N@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C GDHHQS3_k127_3737738_3 1179778.PMM47T1_27769 5.787e-18 86.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,1S44M@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09983 - - - - ko00000 - - - DUF1993 GDHHQS3_k127_3737738_1 1188252.AJYK01000035_gene1556 6.848e-46 167.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,1XXYD@135623|Vibrionales 135623|Vibrionales S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM GDHHQS3_k127_3737738_2 1234364.AMSF01000015_gene3299 7.805e-42 174.0 COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,1RRB8@1236|Gammaproteobacteria,1X4PQ@135614|Xanthomonadales 135614|Xanthomonadales S 3-alpha domain - - - - - - - - - - - - 3-alpha,MOSC GDHHQS3_k127_3737738_0 1040983.AXAE01000014_gene4906 1.647e-124 419.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E PFAM Pyridoxal-dependent decarboxylase - - - - - - - - - - - - Pyridoxal_deC GDHHQS3_k127_3755646_0 1385517.N800_12900 3.527e-48 179.0 COG3118@1|root,COG3118@2|Bacteria,1QWQK@1224|Proteobacteria,1T5NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 GDHHQS3_k127_3755646_1 765914.ThisiDRAFT_2440 1.389e-47 175.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H GDHHQS3_k127_3755646_2 1123073.KB899242_gene1378 5.418e-07 56.0 2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3779227_3 1499968.TCA2_5335 0.0001026 48.0 2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GDHHQS3_k127_3779227_0 330214.NIDE2703 1.436e-85 297.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_3779227_1 700598.Niako_2315 2.037e-81 286.0 COG0463@1|root,COG0463@2|Bacteria,4NW1M@976|Bacteroidetes 976|Bacteroidetes M InterPro IPR008166 - - - - - - - - - - - - Glyco_transf_92 GDHHQS3_k127_3779227_2 1123508.JH636441_gene3513 6.332e-36 146.0 COG0438@1|root,COG0438@2|Bacteria,2J1Z8@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 GDHHQS3_k127_3801173_1 1121035.AUCH01000025_gene3293 4.667e-162 518.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,2KUT9@206389|Rhodocyclales 206389|Rhodocyclales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b GDHHQS3_k127_3801173_5 305900.GV64_09220 3.686e-58 207.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase - - 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000,ko03400 - - - DUF4743,NUDIX GDHHQS3_k127_3801173_2 493475.GARC_4475 1.277e-142 469.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,465Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zn-dependent dipeptidase, microsomal dipeptidase acdP - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 GDHHQS3_k127_3801173_6 1123368.AUIS01000019_gene1216 4.862e-32 133.0 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1SCSV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MobA-Related Protein ygfJ - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 GDHHQS3_k127_3801173_7 570952.ATVH01000015_gene1435 6.984e-23 106.0 COG1396@1|root,COG1396@2|Bacteria,1QV8H@1224|Proteobacteria,2TY0I@28211|Alphaproteobacteria,2JU06@204441|Rhodospirillales 204441|Rhodospirillales K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 GDHHQS3_k127_3801173_0 999547.KI421503_gene122 8.624e-177 562.0 COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein related to capsule biosynthesis enzymes - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C GDHHQS3_k127_3801173_3 1265313.HRUBRA_02377 9.822e-70 249.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,1J5FH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family xdhC2 - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI GDHHQS3_k127_3801173_4 1242864.D187_000213 1.409e-64 229.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - MFS_1,OEP GDHHQS3_k127_3818372_3 1454004.AW11_00969 4.263e-37 146.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria 28216|Betaproteobacteria G carbohydrate binding - - - - - - - - - - - - Glyco_hydro_36,Glyco_transf_36,Glycoamylase GDHHQS3_k127_3818372_0 1120999.JONM01000001_gene1485 7.117e-156 513.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria 28216|Betaproteobacteria G carbohydrate binding - - - - - - - - - - - - Glyco_hydro_36,Glyco_transf_36,Glycoamylase GDHHQS3_k127_3818372_2 420662.Mpe_A2927 2.992e-129 424.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,1KJE6@119065|unclassified Burkholderiales 28216|Betaproteobacteria S AI-2E family transporter yhhT - - - - - - - - - - - AI-2E_transport GDHHQS3_k127_3818372_6 697282.Mettu_0608 6.743e-15 80.0 2FJC4@1|root,34B20@2|Bacteria,1P1U3@1224|Proteobacteria,1SIFI@1236|Gammaproteobacteria,1XFQN@135618|Methylococcales 135618|Methylococcales S Putative Actinobacterial Holin-X, holin superfamily III - - - - - - - - - - - - Phage_holin_3_6 GDHHQS3_k127_3818372_8 697282.Mettu_0610 3.201e-09 64.0 COG4575@1|root,COG4575@2|Bacteria,1PB58@1224|Proteobacteria,1SGWN@1236|Gammaproteobacteria,1XFX4@135618|Methylococcales 135618|Methylococcales S ribosome binding - - - - - - - - - - - - DUF883 GDHHQS3_k127_3818372_7 944435.AXAJ01000004_gene2317 1.866e-12 68.0 2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria,1KB1T@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 GDHHQS3_k127_3818372_4 1316936.K678_09843 4.346e-34 136.0 2C07T@1|root,33YBK@2|Bacteria,1NVKV@1224|Proteobacteria,2USFY@28211|Alphaproteobacteria,2JWKP@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - GDHHQS3_k127_3818372_5 614083.AWQR01000025_gene3719 5.26e-25 108.0 2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_3818372_1 1163407.UU7_04782 1.662e-151 488.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X36N@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug ABC transporter ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_3822695_0 1385517.N800_09470 1.453e-179 581.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GDHHQS3_k127_3822695_1 1122604.JONR01000010_gene3961 4.096e-88 297.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1X4ID@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase GDHHQS3_k127_3822695_3 1384056.N787_10880 4.799e-59 215.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,1XDA2@135614|Xanthomonadales 135614|Xanthomonadales I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 GDHHQS3_k127_3822695_2 1163409.UUA_17557 2.78e-78 265.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1X3W3@135614|Xanthomonadales 135614|Xanthomonadales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C GDHHQS3_k127_3825175_1 314285.KT71_03017 6.61e-74 274.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_3825175_0 1313172.YM304_15210 2.886e-232 729.0 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CMUF@84992|Acidimicrobiia 84992|Acidimicrobiia IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C GDHHQS3_k127_3833131_1 1123073.KB899241_gene2836 1.16e-120 409.0 COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,1T22C@1236|Gammaproteobacteria,1X4WW@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial virulence factor lipase N-terminal - - - - - - - - - - - - Lipase_bact_N GDHHQS3_k127_3833131_2 326297.Sama_3456 3.527e-50 189.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,1S2WK@1236|Gammaproteobacteria,2QBNE@267890|Shewanellaceae 1236|Gammaproteobacteria S Methyl-transferase - - - - - - - - - - - - Methyltransf_11,PCMT,Ubie_methyltran GDHHQS3_k127_3833131_0 1123073.KB899241_gene2833 3.935e-139 447.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales 135614|Xanthomonadales C dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim GDHHQS3_k127_3837533_0 1122951.ATUE01000008_gene91 2.024e-129 418.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,3NIYZ@468|Moraxellaceae 1236|Gammaproteobacteria G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P GDHHQS3_k127_3837533_1 1177154.Y5S_00841 8.602e-19 93.0 COG0642@1|root,COG2205@2|Bacteria,1R9DM@1224|Proteobacteria,1S0EG@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase retS - - ko:K20972 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg GDHHQS3_k127_3887174_1 1242864.D187_007079 4.484e-31 131.0 COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_3887174_0 1442599.JAAN01000020_gene2534 9.198e-240 749.0 COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_3890471_3 159450.NH14_07010 2.064e-14 73.0 COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2VRA3@28216|Betaproteobacteria,1K816@119060|Burkholderiaceae 28216|Betaproteobacteria E glyoxalase - - - ko:K07032 - - - - ko00000 - - - Glyoxalase GDHHQS3_k127_3890471_0 1121937.AUHJ01000011_gene2916 2.596e-146 473.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,4641Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca GO:0001680,GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016437,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042245,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd GDHHQS3_k127_3890471_2 1123253.AUBD01000010_gene2203 4.454e-81 282.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RSKV@1236|Gammaproteobacteria,1X40S@135614|Xanthomonadales 135614|Xanthomonadales GM NAD(P)H-binding - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 GDHHQS3_k127_3890471_1 743721.Psesu_0220 6.085e-90 312.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales 135614|Xanthomonadales M Lytic murein transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L GDHHQS3_k127_3928062_5 1123487.KB892839_gene225 3.08e-07 53.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KUDE@206389|Rhodocyclales 206389|Rhodocyclales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 GDHHQS3_k127_3928062_1 743721.Psesu_0325 1.057e-91 313.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1X42P@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS GDHHQS3_k127_3928062_0 396588.Tgr7_2799 5.686e-133 431.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 GDHHQS3_k127_3928062_2 748247.AZKH_4359 6.068e-69 239.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2VKEU@28216|Betaproteobacteria,2KYH3@206389|Rhodocyclales 206389|Rhodocyclales O maleylacetoacetate isomerase - - 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_N_3 GDHHQS3_k127_3928062_3 640510.BC1001_0291 1.097e-45 167.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,1K027@119060|Burkholderiaceae 28216|Betaproteobacteria Q fumarylacetoacetate (FAA) hydrolase - - 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase GDHHQS3_k127_3970788_7 314285.KT71_06262 4.158e-54 216.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT7@1236|Gammaproteobacteria,1JBPX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_3970788_2 745411.B3C1_13104 4.509e-121 422.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_3970788_10 323261.Noc_0230 1.383e-37 161.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,1S2EP@1236|Gammaproteobacteria,1WZIK@135613|Chromatiales 135613|Chromatiales S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_6 GDHHQS3_k127_3970788_12 1123073.KB899241_gene3044 2.183e-09 70.0 COG2931@1|root,COG2931@2|Bacteria,1NFGA@1224|Proteobacteria,1SBZG@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - CHRD,Spond_N GDHHQS3_k127_3970788_11 323261.Noc_0158 1.193e-20 107.0 COG2335@1|root,COG2931@1|root,COG2335@2|Bacteria,COG2931@2|Bacteria,1NFGA@1224|Proteobacteria,1SBZG@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - CHRD,Spond_N GDHHQS3_k127_3970788_9 1278309.KB907099_gene2599 2.967e-43 167.0 COG0457@1|root,COG0457@2|Bacteria,1RESK@1224|Proteobacteria,1S41N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Tetratricopeptide - - - - - - - - - - - - TPR_11,TPR_16,TPR_2,TPR_8 GDHHQS3_k127_3970788_8 196490.AUEZ01000003_gene3819 9.319e-53 193.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,2U1C3@28211|Alphaproteobacteria,3JR4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DTW MA20_30020 - - ko:K05812 - - - - ko00000 - - - DTW GDHHQS3_k127_3970788_5 1120953.AUBH01000001_gene914 1.627e-100 341.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GDHHQS3_k127_3970788_1 435908.IDSA_11385 5.619e-124 411.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,2QG93@267893|Idiomarinaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GDHHQS3_k127_3970788_4 1279017.AQYJ01000022_gene2698 6.022e-103 341.0 COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter ycfV - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_3970788_3 435908.IDSA_11395 4.94e-115 384.0 COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 GDHHQS3_k127_3970788_6 977880.RALTA_A1537 8.505e-84 284.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria,1K39I@119060|Burkholderiaceae 28216|Betaproteobacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT GDHHQS3_k127_3970788_0 1353531.AZNX01000005_gene3261 2.574e-158 514.0 COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae 28211|Alphaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth GDHHQS3_k127_4007683_3 998088.B565_3839 1.127e-118 390.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1Y3IY@135624|Aeromonadales 135624|Aeromonadales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 GDHHQS3_k127_4007683_7 566466.NOR53_3671 2.631e-29 121.0 COG2119@1|root,COG2119@2|Bacteria,1N85A@1224|Proteobacteria,1SAAX@1236|Gammaproteobacteria,1JB92@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein family UPF0016 - - - - - - - - - - - - UPF0016 GDHHQS3_k127_4007683_5 317025.Tcr_1014 3.765e-102 344.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,461ZY@72273|Thiotrichales 72273|Thiotrichales P TIGRFAM cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux GDHHQS3_k127_4007683_1 251221.35211907 1.394e-199 639.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1G4JM@1117|Cyanobacteria 1117|Cyanobacteria P TrkA-N domain - - - ko:K11745 - - - - ko00000,ko02000 2.A.37.1.1 - - Na_H_Exchanger,TrkA_N GDHHQS3_k127_4007683_6 745310.G432_08025 4.953e-35 140.0 COG3832@1|root,COG3832@2|Bacteria,1N2PR@1224|Proteobacteria,2VGJB@28211|Alphaproteobacteria,2KE45@204457|Sphingomonadales 204457|Sphingomonadales J glyoxalase III activity - - - - - - - - - - - - Polyketide_cyc2 GDHHQS3_k127_4007683_0 1122134.KB893651_gene1922 2.84e-221 694.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1XR0E@135619|Oceanospirillales 135619|Oceanospirillales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_4007683_2 1384056.N787_03865 3.566e-195 622.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X3CQ@135614|Xanthomonadales 135614|Xanthomonadales E Transporter yhiP - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 GDHHQS3_k127_4007683_4 472759.Nhal_1374 1.38e-113 380.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 GDHHQS3_k127_4008322_0 493475.GARC_3253 6.112e-167 536.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 GDHHQS3_k127_4008322_1 69395.JQLZ01000002_gene1029 9.793e-61 213.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2KGN6@204458|Caulobacterales 204458|Caulobacterales C 2Fe-2S -binding domain protein - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 GDHHQS3_k127_4014276_12 1380350.JIAP01000025_gene3373 1.323e-08 65.0 COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2TS08@28211|Alphaproteobacteria 28211|Alphaproteobacteria D sister chromatid segregation - - - - - - - - - - - - - GDHHQS3_k127_4014276_0 935567.JAES01000003_gene173 1.012e-223 704.0 COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,1RMU4@1236|Gammaproteobacteria,1X3ZM@135614|Xanthomonadales 135614|Xanthomonadales J asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GDHHQS3_k127_4014276_9 519989.ECTPHS_12813 1.719e-36 141.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn GDHHQS3_k127_4014276_8 1123354.AUDR01000020_gene2007 6.142e-47 175.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,1KRM1@119069|Hydrogenophilales 119069|Hydrogenophilales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 GDHHQS3_k127_4014276_10 1387197.AWGA01000024_gene684 6.163e-31 122.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 GDHHQS3_k127_4014276_6 935567.JAES01000027_gene1260 2.817e-53 191.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1X6DH@135614|Xanthomonadales 135614|Xanthomonadales J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N GDHHQS3_k127_4014276_2 1123073.KB899243_gene626 1.136e-177 568.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1X3P0@135614|Xanthomonadales 135614|Xanthomonadales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C GDHHQS3_k127_4014276_4 1121015.N789_00945 5.705e-95 322.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1X36D@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N GDHHQS3_k127_4014276_3 1517416.IDAT_00650 5.609e-136 440.0 COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,2QFPQ@267893|Idiomarinaceae 1236|Gammaproteobacteria K Magnesium chelatase, subunit ChlI pspF - - ko:K03974 - - - - ko00000,ko03000 - - - HTH_8,Sigma54_activat GDHHQS3_k127_4014276_1 1123073.KB899243_gene621 2.32e-182 581.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1X3DQ@135614|Xanthomonadales 135614|Xanthomonadales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - ATPase,ChlI GDHHQS3_k127_4014276_11 1123059.KB823014_gene269 2.317e-29 130.0 COG1835@1|root,COG1835@2|Bacteria,1RFYX@1224|Proteobacteria,2VFS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 GDHHQS3_k127_4014276_7 472759.Nhal_0923 1.328e-50 189.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales 135613|Chromatiales S Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm GDHHQS3_k127_4014276_5 187272.Mlg_1938 6.723e-75 255.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1WW6N@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB GDHHQS3_k127_4078988_10 1479237.JMLY01000001_gene1351 4.906e-22 97.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,465IN@72275|Alteromonadaceae 1236|Gammaproteobacteria M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_4078988_5 1163408.UU9_02948 1.649e-124 417.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1X3IV@135614|Xanthomonadales 135614|Xanthomonadales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_4078988_2 1234364.AMSF01000001_gene2380 1.466e-160 521.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1X3Y2@135614|Xanthomonadales 135614|Xanthomonadales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 GDHHQS3_k127_4078988_7 1500890.JQNL01000001_gene1308 1.918e-105 356.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1X3GX@135614|Xanthomonadales 135614|Xanthomonadales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE GDHHQS3_k127_4078988_6 1121013.P873_03180 7.278e-117 387.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1X3JZ@135614|Xanthomonadales 135614|Xanthomonadales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 GDHHQS3_k127_4078988_0 666685.R2APBS1_3268 9.245e-182 580.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1X3C1@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_4078988_8 1283300.ATXB01000002_gene2644 5.753e-90 310.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XE3P@135618|Methylococcales 135618|Methylococcales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N GDHHQS3_k127_4078988_9 391008.Smal_0605 1.759e-44 171.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X5H6@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 GDHHQS3_k127_4078988_1 396588.Tgr7_0774 4.993e-180 571.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales 135613|Chromatiales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA GDHHQS3_k127_4078988_3 1500893.JQNB01000001_gene362 6.301e-152 490.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1X4TG@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin GDHHQS3_k127_4078988_4 1163407.UU7_14178 7.985e-143 458.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC GDHHQS3_k127_4078988_12 477228.YO5_13303 2.418e-06 57.0 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SDJY@1236|Gammaproteobacteria,1Z21M@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 GDHHQS3_k127_4078988_11 380358.XALC_2806 3.534e-15 80.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1X3EY@135614|Xanthomonadales 135614|Xanthomonadales M Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 GDHHQS3_k127_4089420_4 268407.PWYN_18005 0.0002295 48.0 2E083@1|root,32VVX@2|Bacteria,1VWRN@1239|Firmicutes,4HXBR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - GDHHQS3_k127_4089420_1 1340493.JNIF01000003_gene2285 1.262e-41 166.0 COG1442@1|root,COG1442@2|Bacteria,3Y7VU@57723|Acidobacteria 57723|Acidobacteria M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 GDHHQS3_k127_4089420_3 1142394.PSMK_19720 6.732e-32 138.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_4089420_2 1173028.ANKO01000030_gene3286 1.463e-38 158.0 COG0673@1|root,COG0673@2|Bacteria,1G18V@1117|Cyanobacteria,1HG44@1150|Oscillatoriales 1117|Cyanobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.335,1.1.99.28 ko:K00118,ko:K13020 ko00520,map00520 - R10140 RC00182 ko00000,ko00001,ko01000,ko01005 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GDHHQS3_k127_4089420_0 1173028.ANKO01000030_gene3283 1.203e-55 211.0 COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1HH59@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_4204169_1 1123073.KB899241_gene3501 2.302e-29 127.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,1RQTS@1236|Gammaproteobacteria,1X80N@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_3,HlyD_D23 GDHHQS3_k127_4204169_0 1117647.M5M_13023 0.0 1043.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_420515_3 460265.Mnod_2756 5.227e-157 501.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,1JRZF@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit cysB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP GDHHQS3_k127_420515_6 1149133.ppKF707_1544 2.374e-80 275.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,1YFPR@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KT Transcriptional regulatory protein, C terminal kdpE - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GDHHQS3_k127_420515_5 1026882.MAMP_02233 5.1e-114 387.0 COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,45ZRT@72273|Thiotrichales 72273|Thiotrichales T Osmosensitive K channel histidine kinase - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,KdpD GDHHQS3_k127_420515_1 1026882.MAMP_02232 1.429e-218 689.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH GDHHQS3_k127_420515_4 1122137.AQXF01000003_gene2096 1.252e-133 432.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Prokaryotic protein of - - - - - - - - - - - - BKACE GDHHQS3_k127_420515_8 1049564.TevJSym_aa00830 7.21e-42 160.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 GDHHQS3_k127_420515_0 1122599.AUGR01000002_gene3491 3.082e-259 808.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XIYC@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS GDHHQS3_k127_420515_7 1232437.KL662013_gene1341 2.071e-51 194.0 COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions 1224|Proteobacteria I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat GDHHQS3_k127_420515_9 1123256.KB907936_gene2599 7.4e-35 145.0 COG0823@1|root,COG0823@2|Bacteria,1QYUC@1224|Proteobacteria,1S70B@1236|Gammaproteobacteria,1X60J@135614|Xanthomonadales 135614|Xanthomonadales U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - GDHHQS3_k127_420515_2 243233.MCA2438 3.413e-165 529.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XDT1@135618|Methylococcales 135618|Methylococcales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 GDHHQS3_k127_421548_4 1121013.P873_05470 9.164e-09 60.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1X3E2@135614|Xanthomonadales 135614|Xanthomonadales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 GDHHQS3_k127_421548_2 269797.Mbar_A0834 7.917e-38 149.0 COG1309@1|root,arCOG02646@2157|Archaea,2Y6WS@28890|Euryarchaeota,2NAD5@224756|Methanomicrobia 224756|Methanomicrobia K Bacterial regulatory proteins, tetR family - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N GDHHQS3_k127_421548_0 1123073.KB899241_gene2521 1.929e-135 458.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RQM3@1236|Gammaproteobacteria,1X4AK@135614|Xanthomonadales 135614|Xanthomonadales I Cardiolipin synthase - - - - - - - - - - - - PLDc_2 GDHHQS3_k127_421548_3 306281.AJLK01000131_gene1390 7.4e-26 117.0 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1JH83@1189|Stigonemataceae 1117|Cyanobacteria H 4'-phosphopantetheinyl transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS GDHHQS3_k127_421548_1 566466.NOR53_1454 8.192e-107 352.0 COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,1S3GP@1236|Gammaproteobacteria,1J7XP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - ko:K22317 - - - - ko00000 - - - ACP_syn_III,ACP_syn_III_C GDHHQS3_k127_4290802_0 1163617.SCD_n01957 0.0 1056.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria 28216|Betaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C GDHHQS3_k127_4290802_1 1333998.M2A_0184 4.116e-83 299.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,4BQ5X@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 GDHHQS3_k127_4333730_1 1205680.CAKO01000040_gene664 3.078e-50 190.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2JRUX@204441|Rhodospirillales 204441|Rhodospirillales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - - - - - - - - - - Metallophos GDHHQS3_k127_4333730_0 391615.ABSJ01000026_gene120 2.093e-195 632.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1J52P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc GDHHQS3_k127_4333730_4 118163.Ple7327_2767 1.792e-12 70.0 2EA6P@1|root,334BF@2|Bacteria,1G9KH@1117|Cyanobacteria,3VN58@52604|Pleurocapsales 1117|Cyanobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox GDHHQS3_k127_4333730_2 1173027.Mic7113_4762 1.54e-27 112.0 COG3668@1|root,COG3668@2|Bacteria,1G7UC@1117|Cyanobacteria,1HDRH@1150|Oscillatoriales 1117|Cyanobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_4333730_3 1120792.JAFV01000001_gene149 6.613e-18 84.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,36XF0@31993|Methylocystaceae 28211|Alphaproteobacteria G Carbohydrate phosphorylase glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase GDHHQS3_k127_4387301_0 159450.NH14_15235 1.632e-205 647.0 COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,2W9H2@28216|Betaproteobacteria,1KBZG@119060|Burkholderiaceae 28216|Betaproteobacteria E Amino acid permease - - - - - - - - - - - - AA_permease GDHHQS3_k127_4387301_1 6500.XP_005092325.1 6.204e-90 308.0 COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria 33208|Metazoa ET Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP GDHHQS3_k127_4387301_4 1208323.B30_10780 1.351e-38 157.0 COG1712@1|root,COG1712@2|Bacteria,1RCA6@1224|Proteobacteria,2U5XU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function DUF108 - - - - - - - - - - - - DUF108,NAD_binding_3 GDHHQS3_k127_4387301_5 511.JT27_12445 6.002e-32 130.0 2E52M@1|root,32ZVV@2|Bacteria,1Q06R@1224|Proteobacteria,2W4WF@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_4387301_6 743718.Isova_2672 1.057e-18 96.0 COG1920@1|root,COG1920@2|Bacteria,2I0MF@201174|Actinobacteria,4F4S3@85017|Promicromonosporaceae 201174|Actinobacteria S GTP binding - - 2.7.7.68 ko:K14941 ko00680,ko01120,map00680,map01120 M00378 R09397 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CofC GDHHQS3_k127_4387301_2 745310.G432_18305 7.166e-69 241.0 COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,2TS1W@28211|Alphaproteobacteria,2K27G@204457|Sphingomonadales 204457|Sphingomonadales S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored GDHHQS3_k127_4387301_3 1547445.LO80_04115 3.798e-50 193.0 COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Neurotransmitter-gated ion-channel ligand binding domain - - - - - - - - - - - - Neur_chan_LBD,Neur_chan_memb GDHHQS3_k127_440288_2 29495.EA26_15800 2.619e-67 235.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XTJ4@135623|Vibrionales 135623|Vibrionales F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C GDHHQS3_k127_440288_0 767434.Fraau_1736 2.447e-124 415.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1X4GX@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh GDHHQS3_k127_440288_1 1163407.UU7_02432 1.047e-75 270.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_440288_3 1121013.P873_01110 6.603e-37 151.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1X38F@135614|Xanthomonadales 135614|Xanthomonadales E Histidine biosynthesis bifunctional protein HisB hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_like,IGPD,PNK3P GDHHQS3_k127_4414271_0 247634.GPB2148_2426 1.035e-160 518.0 COG1132@1|root,COG1132@2|Bacteria,1R8US@1224|Proteobacteria,1SK1D@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran GDHHQS3_k127_4419526_0 1385515.N791_03975 3.46e-256 798.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1X3UI@135614|Xanthomonadales 135614|Xanthomonadales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C GDHHQS3_k127_4419526_2 225937.HP15_782 5.477e-83 285.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 GDHHQS3_k127_4419526_6 935567.JAES01000030_gene2876 5.51e-23 102.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X76E@135614|Xanthomonadales 135614|Xanthomonadales NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 GDHHQS3_k127_4419526_3 743299.Acife_1759 3.264e-60 216.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,2NCMX@225057|Acidithiobacillales 225057|Acidithiobacillales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm GDHHQS3_k127_4419526_1 1123279.ATUS01000005_gene3306 1.743e-97 331.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1J4EI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 GDHHQS3_k127_4419526_4 1469245.JFBG01000059_gene2398 6.793e-57 206.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N GDHHQS3_k127_4419526_5 1304275.C41B8_12694 1.448e-28 116.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ GDHHQS3_k127_4446777_1 1458427.BAWN01000033_gene1903 2.602e-57 226.0 COG2887@1|root,COG2887@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria 28216|Betaproteobacteria L RecB family exonuclease - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - PDDEXK_1 GDHHQS3_k127_4446777_0 338963.Pcar_1708 4.813e-155 523.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,43S3Q@69541|Desulfuromonadales 28221|Deltaproteobacteria L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C GDHHQS3_k127_4463637_1 1242864.D187_008232 8.528e-30 120.0 2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 GDHHQS3_k127_4463637_2 1380394.JADL01000001_gene2139 5.165e-08 62.0 COG4520@1|root,COG4520@2|Bacteria,1Q8T1@1224|Proteobacteria,2UY9R@28211|Alphaproteobacteria,2JY67@204441|Rhodospirillales 204441|Rhodospirillales M surface antigen - - - - - - - - - - - - - GDHHQS3_k127_4463637_0 234267.Acid_7851 2.757e-106 364.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria 57723|Acidobacteria K Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_4466160_1 270374.MELB17_04972 2.252e-36 139.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K TIGRFAM Addiction module antidote protein, HigA higA - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_4466160_0 864702.OsccyDRAFT_2545 9.329e-177 585.0 COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 GDHHQS3_k127_4496413_0 1198114.AciX9_0014 2.628e-228 726.0 COG3590@1|root,COG3590@2|Bacteria,3Y3CC@57723|Acidobacteria,2JIQB@204432|Acidobacteriia 204432|Acidobacteriia O Endothelin-converting enzyme - - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_4496413_7 1380391.JIAS01000016_gene436 9.342e-76 267.0 COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,2JRQF@204441|Rhodospirillales 204441|Rhodospirillales E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase GDHHQS3_k127_4496413_9 869210.Marky_1499 9.322e-48 190.0 COG2074@1|root,COG2074@2|Bacteria,1WI2U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G 2-phosphoglycerate kinase - - - ko:K05715 - - R02664 RC00002,RC00017 ko00000,ko01000 - - - AAA_33,ATP-cone GDHHQS3_k127_4496413_5 883110.HMPREF9260_00361 9.729e-79 279.0 COG3635@1|root,COG3635@2|Bacteria,1TQ5S@1239|Firmicutes,4HCYI@91061|Bacilli 91061|Bacilli G 2,3-bisphosphoglycerate-independent phosphoglycerate mutase - - - - - - - - - - - - Metalloenzyme,PhosphMutase GDHHQS3_k127_4496413_4 1454004.AW11_02489 2.351e-117 384.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2VTJU@28216|Betaproteobacteria 28216|Betaproteobacteria P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 GDHHQS3_k127_4496413_8 1454004.AW11_02488 6.196e-72 256.0 COG0394@1|root,COG0704@1|root,COG0394@2|Bacteria,COG0704@2|Bacteria 2|Bacteria P negative regulation of phosphate transmembrane transport phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 ko:K01104,ko:K02039,ko:K03741 - - - - ko00000,ko01000 - - - PhoU GDHHQS3_k127_4496413_1 522306.CAP2UW1_1749 1.678e-140 452.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria 28216|Betaproteobacteria P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GDHHQS3_k127_4496413_2 522306.CAP2UW1_1750 1.446e-132 427.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GDHHQS3_k127_4496413_3 522306.CAP2UW1_1751 2.672e-126 410.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - - - - - - - - - - ABC_tran GDHHQS3_k127_4496413_6 1454004.AW11_02484 8.261e-77 266.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran GDHHQS3_k127_4502982_0 1121012.AUKX01000039_gene3157 5.666e-43 173.0 COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,1I0DS@117743|Flavobacteriia,23G9P@178469|Arenibacter 976|Bacteroidetes S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS GDHHQS3_k127_4502982_1 203122.Sde_0721 1.077e-27 125.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,469B1@72275|Alteromonadaceae 1236|Gammaproteobacteria M TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_4521957_22 644107.SL1157_1223 3.175e-34 147.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TYZY@28211|Alphaproteobacteria,4NDTN@97050|Ruegeria 28211|Alphaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg GDHHQS3_k127_4521957_7 765912.Thimo_3618 1.114e-156 501.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1WWT0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D GDHHQS3_k127_4521957_11 631362.Thi970DRAFT_00489 8.738e-110 367.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase GDHHQS3_k127_4521957_20 713586.KB900536_gene1837 3.142e-47 176.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1WWA2@135613|Chromatiales 135613|Chromatiales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI GDHHQS3_k127_4521957_18 713586.KB900536_gene1112 6.798e-54 197.0 COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria,1X10E@135613|Chromatiales 135613|Chromatiales S Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH GDHHQS3_k127_4521957_19 414684.RC1_0584 6.491e-51 192.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2JRUZ@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx GDHHQS3_k127_4521957_25 713586.KB900536_gene1713 6.729e-22 107.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1WZKG@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4426) - - - - - - - - - - - - DUF4426 GDHHQS3_k127_4521957_21 318161.Sden_2684 3.205e-40 155.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,2Q8UQ@267890|Shewanellaceae 1236|Gammaproteobacteria S YGGT family yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT GDHHQS3_k127_4521957_16 1121013.P873_13235 4.867e-71 249.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1X56M@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer GDHHQS3_k127_4521957_17 1232683.ADIMK_0889 5.894e-70 243.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N GDHHQS3_k127_4521957_4 935567.JAES01000015_gene2807 2.385e-166 529.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1X3Y4@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE GDHHQS3_k127_4521957_8 1205753.A989_15978 1.928e-147 475.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X4F6@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE GDHHQS3_k127_4521957_14 935863.AWZR01000007_gene261 1.602e-102 340.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1X41P@135614|Xanthomonadales 135614|Xanthomonadales KT XRE family transcriptional regulator VL23_03445 - - - - - - - - - - - Response_reg,Trans_reg_C GDHHQS3_k127_4521957_13 1384054.N790_08665 2.795e-106 359.0 COG0642@1|root,COG0642@2|Bacteria,1R514@1224|Proteobacteria,1T1KV@1236|Gammaproteobacteria,1X3D5@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase colS - - - - - - - - - - - HATPase_c,HisKA GDHHQS3_k127_4521957_24 1123253.AUBD01000010_gene2107 1.457e-25 111.0 2ET5N@1|root,33KPQ@2|Bacteria,1NG8Z@1224|Proteobacteria,1SH39@1236|Gammaproteobacteria,1X73G@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_4521957_26 1384054.N790_07045 1.717e-08 66.0 29NIW@1|root,309GT@2|Bacteria,1QSW3@1224|Proteobacteria,1RWGT@1236|Gammaproteobacteria,1X3TI@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_4521957_15 243233.MCA2020 2.234e-80 273.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1XEZK@135618|Methylococcales 135618|Methylococcales O Redoxin - - - - - - - - - - - - AhpC-TSA GDHHQS3_k127_4521957_2 1163407.UU7_08990 1.496e-300 936.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1X498@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N GDHHQS3_k127_4521957_5 314278.NB231_13371 1.871e-163 519.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WXC0@135613|Chromatiales 135613|Chromatiales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N GDHHQS3_k127_4521957_6 697282.Mettu_2550 9.989e-161 515.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XDUK@135618|Methylococcales 135618|Methylococcales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK GDHHQS3_k127_4521957_3 1163407.UU7_08965 3.611e-167 539.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1X3J7@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C GDHHQS3_k127_4521957_9 1429851.X548_14735 3.83e-145 467.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1X34A@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the class I fructose-bisphosphate aldolase family - - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic GDHHQS3_k127_4521957_1 349124.Hhal_1029 1.952e-306 956.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales 135613|Chromatiales C PFAM malic - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic GDHHQS3_k127_4521957_0 1122134.KB893651_gene2042 0.0 1302.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N GDHHQS3_k127_4521957_10 1234364.AMSF01000085_gene2875 2.506e-143 469.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1X3PC@135614|Xanthomonadales 135614|Xanthomonadales C acetyltransferase component of pyruvate dehydrogenase complex aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding GDHHQS3_k127_4521957_23 1005395.CSV86_13210 1.437e-28 121.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1YYGY@136845|Pseudomonas putida group 1236|Gammaproteobacteria S gag-polyprotein putative aspartyl protease orf - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas GDHHQS3_k127_4521957_12 1163409.UUA_14184 2.118e-107 362.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales 135614|Xanthomonadales C dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim GDHHQS3_k127_4524178_0 1117647.M5M_13023 1.162e-297 934.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_4524178_1 1122137.AQXF01000003_gene1871 7.306e-50 191.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,2VFH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 GDHHQS3_k127_4553917_0 439497.RR11_2029 4.555e-148 479.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,4NB9H@97050|Ruegeria 28211|Alphaproteobacteria E Aminotransferase, class V - - - - - - - - - - - - Aminotran_5 GDHHQS3_k127_4553917_1 1123257.AUFV01000006_gene449 2.725e-41 155.0 COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,1S1AU@1236|Gammaproteobacteria,1XCD3@135614|Xanthomonadales 135614|Xanthomonadales M OmpA family - - - - - - - - - - - - OMP_b-brl,OmpA GDHHQS3_k127_4562190_1 247634.GPB2148_538 1.987e-207 659.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF87 - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 GDHHQS3_k127_4562190_4 1121015.N789_03695 1.119e-161 522.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1S1HS@1236|Gammaproteobacteria,1X48P@135614|Xanthomonadales 135614|Xanthomonadales Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf GDHHQS3_k127_4562190_0 1163407.UU7_02732 3.171e-219 691.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1X3ZZ@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran GDHHQS3_k127_4562190_13 1286106.MPL1_07837 4.344e-39 153.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,4618X@72273|Thiotrichales 72273|Thiotrichales S Colicin V production protein - - - ko:K03558 - - - - ko00000 - - - Colicin_V GDHHQS3_k127_4562190_14 767434.Fraau_2171 1.11e-17 94.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SH3N@1236|Gammaproteobacteria,1X4NY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - SPOR GDHHQS3_k127_4562190_7 1500893.JQNB01000001_gene3315 3.162e-102 347.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1X32Z@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M GDHHQS3_k127_4562190_5 1384056.N787_00170 4.272e-128 415.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1X3KH@135614|Xanthomonadales 135614|Xanthomonadales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans GDHHQS3_k127_4562190_9 1121015.N789_01680 4.651e-87 295.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1X40W@135614|Xanthomonadales 135614|Xanthomonadales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA GDHHQS3_k127_4562190_2 2340.JV46_26460 8.23e-196 619.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1J5D5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP GDHHQS3_k127_4562190_11 580332.Slit_2116 1.799e-57 208.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales 28216|Betaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI GDHHQS3_k127_4562190_8 1158756.AQXQ01000008_gene2473 5.303e-93 312.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales 135613|Chromatiales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 GDHHQS3_k127_4562190_12 1385517.N800_13005 7.252e-51 201.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1X4MQ@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - TPR_19 GDHHQS3_k127_4562190_6 713586.KB900536_gene67 5.828e-127 415.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC GDHHQS3_k127_4562190_3 519989.ECTPHS_11080 1.559e-163 520.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales 135613|Chromatiales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt GDHHQS3_k127_4562190_10 519989.ECTPHS_11070 8.058e-86 292.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS GDHHQS3_k127_4562218_2 1116472.MGMO_45c00700 8.555e-31 126.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales 135618|Methylococcales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N GDHHQS3_k127_4562218_0 1123377.AUIV01000015_gene223 1.544e-217 681.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1X3U8@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the reversible formation of glyoxylate and succinate from isocitrate aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL GDHHQS3_k127_4562218_1 519989.ECTPHS_03999 5.93e-47 173.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RXZ5@1236|Gammaproteobacteria,1WXP8@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator, LysR - - - - - - - - - - - - HTH_1,LysR_substrate GDHHQS3_k127_4573828_2 1286106.MPL1_05569 5.046e-25 121.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,460M8@72273|Thiotrichales 72273|Thiotrichales M LppC putative lipoprotein - - - ko:K07121 - - - - ko00000 - - - LppC GDHHQS3_k127_4573828_0 1385515.N791_03410 1.815e-87 297.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1X4QV@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase GDHHQS3_k127_4573828_1 440512.C211_08439 2.476e-28 127.0 2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_458254_5 1453501.JELR01000002_gene1068 2.034e-90 308.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA GDHHQS3_k127_458254_4 1123073.KB899241_gene2294 1.819e-114 376.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1X3GV@135614|Xanthomonadales 135614|Xanthomonadales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA GDHHQS3_k127_458254_0 1121937.AUHJ01000002_gene3554 0.0 1234.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,4658W@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P GDHHQS3_k127_458254_1 518766.Rmar_1656 1.59e-241 773.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Belongs to the Orn Lys Arg decarboxylase class-II family - - 2.7.2.4,4.1.1.20 ko:K00928,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC GDHHQS3_k127_458254_3 1429851.X548_17075 1.362e-114 375.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1X3U9@135614|Xanthomonadales 135614|Xanthomonadales K RNA polymerase sigma factor RpoH rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 GDHHQS3_k127_458254_7 1384054.N790_13950 1.854e-55 207.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1X3UJ@135614|Xanthomonadales 135614|Xanthomonadales D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX GDHHQS3_k127_458254_6 1123073.KB899241_gene2878 1.003e-84 286.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1X4HD@135614|Xanthomonadales 135614|Xanthomonadales D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran GDHHQS3_k127_458254_2 396588.Tgr7_0356 8.204e-158 509.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C GDHHQS3_k127_4592078_1 1550073.JROH01000018_gene435 1.173e-21 101.0 COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,2U1JF@28211|Alphaproteobacteria,2KEB9@204457|Sphingomonadales 204457|Sphingomonadales S Cupin domain - - - - - - - - - - - - Cupin_2 GDHHQS3_k127_4592078_0 795666.MW7_0585 1.297e-82 287.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC GDHHQS3_k127_45966_1 396588.Tgr7_0025 1.413e-108 360.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 GDHHQS3_k127_45966_10 879212.DespoDRAFT_01664 0.0002496 43.0 COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MP0R@213118|Desulfobacterales 28221|Deltaproteobacteria P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 GDHHQS3_k127_45966_4 227377.CBU_2081 9.979e-41 171.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1JCX6@118969|Legionellales 118969|Legionellales H HemY protein N-terminus hemY - - ko:K02498 - - - - ko00000 - - - HemY_N GDHHQS3_k127_45966_9 1397528.Q671_00180 1.127e-16 93.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XH3M@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis hemX - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX GDHHQS3_k127_45966_8 1163407.UU7_06718 3.13e-19 97.0 COG1587@1|root,COG1587@2|Bacteria,1PBXH@1224|Proteobacteria,1RV28@1236|Gammaproteobacteria,1X6RF@135614|Xanthomonadales 135614|Xanthomonadales H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 GDHHQS3_k127_45966_3 159087.Daro_4073 2.32e-75 255.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,2KWH9@206389|Rhodocyclales 206389|Rhodocyclales S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 GDHHQS3_k127_45966_7 477228.YO5_02031 4.446e-30 122.0 COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Plasmid maintenance system killer - - - ko:K07334 - - - - ko00000,ko02048 - - - HigB-like_toxin GDHHQS3_k127_45966_6 713586.KB900536_gene2391 2.959e-35 138.0 COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,1S8Z4@1236|Gammaproteobacteria,1WZ50@135613|Chromatiales 135613|Chromatiales K TIGRFAM Addiction module antidote protein, HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_45966_0 861299.J421_5951 2.175e-111 390.0 COG0642@1|root,COG2205@2|Bacteria 861299.J421_5951|- T PhoQ Sensor - - - - - - - - - - - - - GDHHQS3_k127_45966_2 436717.AOLE_18095 2.403e-96 328.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,3NIRA@468|Moraxellaceae 1236|Gammaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849 Porphobil_deam,Porphobil_deamC GDHHQS3_k127_45966_5 1163408.UU9_04639 1.032e-38 150.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X3HP@135614|Xanthomonadales 135614|Xanthomonadales KT Response regulator of the LytR AlgR family - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg GDHHQS3_k127_4609690_3 1123504.JQKD01000008_gene5394 3.848e-22 113.0 COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,1QUP3@1224|Proteobacteria,2VM2I@28216|Betaproteobacteria,4AFJ9@80864|Comamonadaceae 28216|Betaproteobacteria K CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_16 GDHHQS3_k127_4609690_2 45351.EDO42421 6.62e-26 119.0 KOG3714@1|root,KOG3714@2759|Eukaryota,39URU@33154|Opisthokonta,3BFDN@33208|Metazoa 33208|Metazoa O Astacin (Peptidase family M12A) - - - - - - - - - - - - Astacin GDHHQS3_k127_4609690_4 398767.Glov_0179 1.418e-11 70.0 COG3620@1|root,COG3620@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K18830 - - - - ko00000,ko02048,ko03000 - - - DUF4065,HTH_3,MqsA_antitoxin GDHHQS3_k127_4609690_5 243233.MCA2139 6.378e-09 60.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XDIR@135618|Methylococcales 135618|Methylococcales O Mg chelatase-related protein - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C GDHHQS3_k127_4609690_1 1255043.TVNIR_2901 1.038e-191 610.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein ygdH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox GDHHQS3_k127_4609690_0 1122194.AUHU01000011_gene1720 0.0 1135.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec GDHHQS3_k127_461272_2 1198452.Jab_2c22660 5.547e-41 155.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,47372@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - - - - - - - - - - - DNA_pol3_alpha,HHH_6,PHP GDHHQS3_k127_461272_0 1123073.KB899244_gene261 5.027e-295 937.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X5CT@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran GDHHQS3_k127_461272_1 1121104.AQXH01000001_gene1412 1.574e-89 302.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran GDHHQS3_k127_4613242_2 1384056.N787_00475 1.341e-67 255.0 COG1404@1|root,COG1404@2|Bacteria,1R5Y1@1224|Proteobacteria,1SEMA@1236|Gammaproteobacteria,1X940@135614|Xanthomonadales 135614|Xanthomonadales O Subtilase family - - - - - - - - - - - - Inhibitor_I9,Peptidase_S8 GDHHQS3_k127_4613242_0 1045855.DSC_08470 3.282e-152 493.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 GDHHQS3_k127_4613242_1 631362.Thi970DRAFT_00974 7.649e-136 443.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales 135613|Chromatiales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth GDHHQS3_k127_4613242_3 1187848.AJYQ01000121_gene3204 1.832e-23 100.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XTCG@135623|Vibrionales 135623|Vibrionales F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT GDHHQS3_k127_4613699_1 1121013.P873_01025 1.26e-143 464.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 ko:K09065 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N GDHHQS3_k127_4613699_0 1192034.CAP_0320 1.302e-144 468.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YUQY@29|Myxococcales 28221|Deltaproteobacteria E Arginosuccinate synthase argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth GDHHQS3_k127_4613699_5 1385515.N791_01770 5.125e-83 288.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1X48W@135614|Xanthomonadales 135614|Xanthomonadales E Acetylornithine deacetylase argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_4613699_3 448385.sce0073 1.227e-125 419.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,43A0N@68525|delta/epsilon subdivisions,2X1X7@28221|Deltaproteobacteria,2YWBC@29|Myxococcales 28221|Deltaproteobacteria E NAT, N-acetyltransferase, of N-acetylglutamate synthase - - 1.2.1.38,2.3.1.1,2.7.2.8 ko:K12659,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649,R03443 RC00002,RC00004,RC00043,RC00064,RC00684 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,NAT GDHHQS3_k127_4613699_4 1123253.AUBD01000001_gene1673 9.397e-91 309.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1X32E@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC GDHHQS3_k127_4613699_2 1192034.CAP_0324 2.944e-141 461.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales 28221|Deltaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1,NUDIX GDHHQS3_k127_4629513_0 745411.B3C1_17162 5.101e-49 198.0 COG4967@1|root,COG4967@2|Bacteria,1R7RM@1224|Proteobacteria,1S1SU@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_4629513_1 380703.AHA_0695 1.102e-19 103.0 COG4726@1|root,COG4726@2|Bacteria,1RCDE@1224|Proteobacteria,1S36A@1236|Gammaproteobacteria,1Y5JX@135624|Aeromonadales 135624|Aeromonadales NU Pilus assembly protein PilX - - - - - - - - - - - - - GDHHQS3_k127_4629513_2 1232683.ADIMK_0980 1.729e-17 93.0 COG4795@1|root,COG4795@2|Bacteria,1RHSZ@1224|Proteobacteria,1S374@1236|Gammaproteobacteria,468S3@72275|Alteromonadaceae 1236|Gammaproteobacteria U prepilin peptidase dependent protein ppdB - - ko:K02680 - - - - ko00000,ko02044 - - - N_methyl GDHHQS3_k127_4660347_1 1161401.ASJA01000016_gene1380 2.122e-100 337.0 COG1629@1|root,COG1629@2|Bacteria,1QYF4@1224|Proteobacteria,2TXUT@28211|Alphaproteobacteria,440U3@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec GDHHQS3_k127_4660347_0 366602.Caul_0680 6.072e-115 380.0 COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,2KFGU@204458|Caulobacterales 204458|Caulobacterales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_4660347_2 1201293.AKXQ01000034_gene947 9.01e-16 84.0 COG0428@1|root,COG0428@2|Bacteria,1QZBY@1224|Proteobacteria,1T456@1236|Gammaproteobacteria 1236|Gammaproteobacteria P transporter - - - - - - - - - - - - ArsP_1 GDHHQS3_k127_4671842_1 243233.MCA2097 6.647e-139 444.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XEJP@135618|Methylococcales 135618|Methylococcales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 GDHHQS3_k127_4671842_4 1123279.ATUS01000001_gene1050 3.052e-18 91.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1J6Y3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG2927 DNA polymerase III, chi subunit holC GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi GDHHQS3_k127_4671842_0 1123073.KB899241_gene3148 9.593e-158 512.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1X38B@135614|Xanthomonadales 135614|Xanthomonadales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N GDHHQS3_k127_4671842_2 519989.ECTPHS_04935 3.863e-64 233.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ GDHHQS3_k127_4671842_3 1247024.JRLH01000001_gene827 8.246e-27 121.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S permease lptG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iSSON_1240.SSON_4447 YjgP_YjgQ GDHHQS3_k127_4675114_0 768671.ThimaDRAFT_0301 2.806e-227 719.0 COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,1S0TR@1236|Gammaproteobacteria,1WZ58@135613|Chromatiales 135613|Chromatiales P Cytochrome c554 and c-prime - - - - - - - - - - - - - GDHHQS3_k127_4675114_1 1535422.ND16A_2692 5.968e-25 116.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome c cc4 - - - - - - - - - - - Cytochrom_C GDHHQS3_k127_4684469_1 1382304.JNIL01000001_gene1390 1.037e-106 355.0 COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4HDCE@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF2088) larA - 5.1.2.1 ko:K22373 ko00620,map00620 - R01450 RC00519 ko00000,ko00001,ko01000 - - - DUF2088 GDHHQS3_k127_4684469_0 246194.CHY_0789 5.564e-140 466.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,42ERP@68295|Thermoanaerobacterales 186801|Clostridia C Aldehyde ferredoxin oxidoreductase aor - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS09915 AFOR_C,AFOR_N GDHHQS3_k127_4684469_3 666510.ASAC_1296 2.592e-17 94.0 COG1142@1|root,arCOG01502@2157|Archaea 2157|Archaea C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein porF - - ko:K00196 ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200 - R07157,R08034 RC00250,RC02800 ko00000,ko00001 - - - Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_9 GDHHQS3_k127_4684469_2 42256.RradSPS_3024 1.129e-34 147.0 COG1830@1|root,COG1830@2|Bacteria,2IB09@201174|Actinobacteria 201174|Actinobacteria G Aldolase - - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC GDHHQS3_k127_4688882_7 1121033.AUCF01000030_gene161 1.129e-18 89.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria,2JQI9@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF GDHHQS3_k127_4688882_6 1492922.GY26_15385 3.966e-30 124.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1J6YP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF4212 GDHHQS3_k127_4688882_5 493475.GARC_1985 7.234e-61 229.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K01993 - - - - ko00000 - - - HlyD_D23 GDHHQS3_k127_4688882_0 493475.GARC_1986 3.085e-163 522.0 COG0577@1|root,COG0577@2|Bacteria,1PVW8@1224|Proteobacteria,1SZYK@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - - - - - - - - - - FtsX GDHHQS3_k127_4688882_3 404589.Anae109_3179 1.004e-95 336.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin,cNMP_binding GDHHQS3_k127_4688882_1 1026882.MAMP_02004 2.786e-123 402.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,4609Z@72273|Thiotrichales 72273|Thiotrichales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb GDHHQS3_k127_4688882_4 1123392.AQWL01000002_gene1981 1.706e-63 227.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KSU5@119069|Hydrogenophilales 119069|Hydrogenophilales C Ferric reductase like transmembrane component - - - - - - - - - - - - Ferric_reduct GDHHQS3_k127_4688882_2 1146883.BLASA_0113 3.872e-109 361.0 COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4EU9C@85013|Frankiales 201174|Actinobacteria I Alpha/beta hydrolase family dhmA - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 GDHHQS3_k127_4700482_0 1122613.ATUP01000001_gene1705 2.139e-129 426.0 COG0520@1|root,COG0520@2|Bacteria,1N124@1224|Proteobacteria,2TZXB@28211|Alphaproteobacteria,43ZHD@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 GDHHQS3_k127_4700482_2 582899.Hden_0696 1.136e-63 221.0 COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glycine cleavage H-protein - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H GDHHQS3_k127_4700482_3 582899.Hden_0695 1.857e-41 160.0 2AKRU@1|root,31BIQ@2|Bacteria,1Q7DM@1224|Proteobacteria,2UEKS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_4700482_1 1417296.U879_08095 8.476e-85 282.0 COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2U4AQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG GDHHQS3_k127_4705086_2 1049564.TevJSym_bl00230 1.175e-122 404.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225 AMIN,Amidase_3,LysM GDHHQS3_k127_4705086_1 1123253.AUBD01000008_gene401 6.404e-129 427.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1X4XY@135614|Xanthomonadales 135614|Xanthomonadales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C GDHHQS3_k127_4705086_4 305900.GV64_03890 1.978e-65 227.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XHJY@135619|Oceanospirillales 135619|Oceanospirillales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C GDHHQS3_k127_4705086_3 90371.CY43_22735 1.797e-108 362.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,3ZM4H@590|Salmonella 1236|Gammaproteobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT GDHHQS3_k127_4705086_5 105559.Nwat_0529 2.115e-34 134.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1WYTY@135613|Chromatiales 135613|Chromatiales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq GDHHQS3_k127_4705086_0 187272.Mlg_0574 8.883e-132 433.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales 135613|Chromatiales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 GDHHQS3_k127_4705086_6 765910.MARPU_07610 0.0004132 43.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales 135613|Chromatiales O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N GDHHQS3_k127_4723893_3 1121935.AQXX01000068_gene5863 4.148e-129 416.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 GDHHQS3_k127_4723893_2 1411685.U062_00654 1.354e-168 544.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RZHC@1236|Gammaproteobacteria 1236|Gammaproteobacteria C acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_4723893_4 314285.KT71_07889 1.167e-110 369.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1S9S5@1236|Gammaproteobacteria,1J8AP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_4723893_7 1323663.AROI01000004_gene2064 5.835e-43 164.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S72R@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Dehydratase - - - - - - - - - - - - MaoC_dehydratas GDHHQS3_k127_4723893_5 314287.GB2207_00240 6.338e-110 366.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,1SYCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N GDHHQS3_k127_4723893_0 1038860.AXAP01000008_gene5969 8.975e-256 796.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2UQJ2@28211|Alphaproteobacteria,3K2BQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - - - - - - - - - - HpaB,HpaB_N GDHHQS3_k127_4723893_1 1049564.TevJSym_ac01450 4.601e-187 602.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1J5AY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 GDHHQS3_k127_4723893_8 472759.Nhal_0877 7.779e-32 139.0 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1SBFD@1236|Gammaproteobacteria,1X23N@135613|Chromatiales 135613|Chromatiales S Protein conserved in bacteria - - - - - - - - - - - - - GDHHQS3_k127_4723893_6 396588.Tgr7_0978 1.153e-61 220.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales 135613|Chromatiales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N GDHHQS3_k127_4723893_9 349124.Hhal_1775 5.384e-30 120.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS GDHHQS3_k127_4735126_1 926549.KI421517_gene2642 2.835e-76 281.0 COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - CarbopepD_reg_2,Plug,TonB_dep_Rec GDHHQS3_k127_4735126_0 1461693.ATO10_12494 4.304e-137 448.0 COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,2TS26@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC GDHHQS3_k127_474902_1 1244869.H261_14160 4.656e-195 614.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_474902_3 76114.ebA2050 3.901e-139 458.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,2KW5T@206389|Rhodocyclales 206389|Rhodocyclales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C GDHHQS3_k127_474902_4 1244869.H261_14155 3.485e-20 93.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS GDHHQS3_k127_474902_0 1056512.D515_01370 3.675e-209 657.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1XYXH@135623|Vibrionales 135623|Vibrionales H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 GDHHQS3_k127_474902_2 1121374.KB891576_gene678 5.977e-158 505.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,1RVX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CI Aldehyde dehydrogenase paaN GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991 Aldedh,MaoC_dehydratas GDHHQS3_k127_478080_2 1123269.NX02_25120 1.033e-18 87.0 COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,2U5XC@28211|Alphaproteobacteria,2K2S2@204457|Sphingomonadales 204457|Sphingomonadales M Nucleotidyltransferase - - - - - - - - - - - - NTP_transf_3,NTP_transferase GDHHQS3_k127_478080_0 1088721.NSU_0815 3.448e-183 589.0 COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2V983@28211|Alphaproteobacteria,2K2B5@204457|Sphingomonadales 204457|Sphingomonadales E GMC oxidoreductase - - - - - - - - - - - - DAO,GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_478080_4 1150599.MPHLEI_10349 1.217e-05 55.0 COG3832@1|root,COG3832@2|Bacteria,2IMWI@201174|Actinobacteria,23A7C@1762|Mycobacteriaceae 201174|Actinobacteria S cyclase dehydrase - - - - - - - - - - - - Polyketide_cyc2 GDHHQS3_k127_478080_1 1121875.KB907548_gene1638 2.84e-109 370.0 COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes 976|Bacteroidetes C oxidoreductase - - - - - - - - - - - - - GDHHQS3_k127_478080_3 109871.XP_006675196.1 3.84e-12 72.0 COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi 4751|Fungi T cAMP-dependent protein kinase regulatory subunit PKAR GO:0000003,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032502,GO:0033036,GO:0033043,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045761,GO:0045762,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051641,GO:0051704,GO:0051716,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0097271,GO:0098772,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1902531,GO:1902532,GO:1903664,GO:1903666 - ko:K04739 ko04910,map04910 - - - ko00000,ko00001 - - - RIIa,cNMP_binding GDHHQS3_k127_4788839_3 1121374.KB891589_gene70 1.892e-11 65.0 COG5631@1|root,COG5631@2|Bacteria,1RDM3@1224|Proteobacteria,1S11S@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcription regulator, contains HTH domain (MarR family) - - - - - - - - - - - - HTH_27 GDHHQS3_k127_4788839_0 1408254.T458_07935 5.534e-133 439.0 COG1457@1|root,COG1457@2|Bacteria,1TWBM@1239|Firmicutes,4HA08@91061|Bacilli,270I3@186822|Paenibacillaceae 91061|Bacilli F Permease for cytosine/purines, uracil, thiamine, allantoin - - - - - - - - - - - - Transp_cyt_pur GDHHQS3_k127_4788839_1 1218074.BAXZ01000003_gene781 2.068e-53 207.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VSFQ@28216|Betaproteobacteria,1K13T@119060|Burkholderiaceae 28216|Betaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 GDHHQS3_k127_4788839_2 1120972.AUMH01000023_gene560 5.323e-16 79.0 COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4HINQ@91061|Bacilli 91061|Bacilli C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 GDHHQS3_k127_4799487_2 84531.JMTZ01000033_gene281 3.267e-98 323.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X5GF@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 GDHHQS3_k127_4799487_0 290512.Paes_0726 1.681e-163 529.0 COG1236@1|root,COG1236@2|Bacteria,1FER3@1090|Chlorobi 1090|Chlorobi J PFAM beta-lactamase domain protein - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL GDHHQS3_k127_4799487_3 517417.Cpar_1378 3.641e-87 304.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1FFEV@1090|Chlorobi 1090|Chlorobi O Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_8 GDHHQS3_k127_4799487_6 1123518.ARWI01000001_gene911 4.896e-14 78.0 2DW1F@1|root,33Y3G@2|Bacteria,1NQFD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_4799487_5 795359.TOPB45_0353 1.142e-15 80.0 COG1724@1|root,COG1724@2|Bacteria,2GIPV@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria N HicA toxin of bacterial toxin-antitoxin, - - - - - - - - - - - - HicA_toxin GDHHQS3_k127_4799487_4 228410.NE1268 3.972e-27 112.0 COG1598@1|root,COG1598@2|Bacteria,1Q9NN@1224|Proteobacteria,2W6S7@28216|Betaproteobacteria,374GI@32003|Nitrosomonadales 28216|Betaproteobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - GDHHQS3_k127_4799487_1 1265313.HRUBRA_01348 4.3e-124 413.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - DUF222,HNH GDHHQS3_k127_480410_1 1158292.JPOE01000005_gene886 3.734e-46 169.0 COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2VSFK@28216|Betaproteobacteria,1KP1A@119065|unclassified Burkholderiales 28216|Betaproteobacteria P DsrE/DsrF-like family - - - ko:K06039 - - - - ko00000 - - - DrsE GDHHQS3_k127_480410_0 1163617.SCD_n00142 8.066e-155 494.0 COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2VI3X@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 GDHHQS3_k127_4818545_0 1123073.KB899241_gene2724 5.154e-170 565.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1X4Z1@135614|Xanthomonadales 135614|Xanthomonadales G phosphomannomutase - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GDHHQS3_k127_4818545_2 1120970.AUBZ01000006_gene1131 1.493e-66 229.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,466EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase GDHHQS3_k127_4818545_1 322710.Avin_02940 5.532e-77 265.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC GDHHQS3_k127_4818545_3 857087.Metme_0129 1.659e-35 136.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1XFJ2@135618|Methylococcales 135618|Methylococcales J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 GDHHQS3_k127_4818545_5 1202962.KB907175_gene12 2.922e-23 100.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 GDHHQS3_k127_4818545_4 379066.GAU_3068 1.991e-35 149.0 COG0627@1|root,COG0627@2|Bacteria,1ZU1Y@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Putative esterase - - - - - - - - - - - - Esterase GDHHQS3_k127_4818545_7 1248760.ANFZ01000018_gene659 7.687e-16 85.0 COG2026@1|root,COG2026@2|Bacteria,1MZ76@1224|Proteobacteria,2UF8I@28211|Alphaproteobacteria,2KB18@204457|Sphingomonadales 204457|Sphingomonadales DJ ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_4818545_6 1458357.BG58_10285 5.312e-17 83.0 COG2161@1|root,COG2161@2|Bacteria 2|Bacteria D toxin-antitoxin pair type II binding yafN GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0044092,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K18923,ko:K19161 - - - - ko00000,ko02048 - - - PhdYeFM_antitox GDHHQS3_k127_4824388_0 713586.KB900536_gene926 2.045e-213 675.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV GDHHQS3_k127_4824388_4 1384056.N787_11825 4.972e-42 173.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1X3GK@135614|Xanthomonadales 135614|Xanthomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 GDHHQS3_k127_4824388_1 472759.Nhal_0691 2.722e-167 535.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales 135613|Chromatiales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE GDHHQS3_k127_4824388_3 1234364.AMSF01000017_gene1428 8.119e-66 242.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1X3C4@135614|Xanthomonadales 135614|Xanthomonadales O abc transporter, permease sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 GDHHQS3_k127_4824388_2 1500890.JQNL01000001_gene1120 8.473e-79 265.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1X32R@135614|Xanthomonadales 135614|Xanthomonadales O Part of SUF system involved in inserting iron-sulfur clusters into proteins sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran GDHHQS3_k127_4824995_0 1123253.AUBD01000005_gene100 2.534e-218 689.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,1RY9G@1236|Gammaproteobacteria,1X3B2@135614|Xanthomonadales 135614|Xanthomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_4824995_1 1335757.SPICUR_06225 2.158e-81 280.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales 135613|Chromatiales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 GDHHQS3_k127_4824995_2 1049564.TevJSym_ah00310 2.337e-17 90.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SWYJ@1236|Gammaproteobacteria,1J6IG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Anti sigma-E protein RseA, N-terminal domain - - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_N GDHHQS3_k127_4828129_1 1449049.JONW01000005_gene1908 2.247e-58 205.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2KFS1@204458|Caulobacterales 204458|Caulobacterales E PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein - - 4.4.1.1,4.4.1.11 ko:K01758,ko:K01761 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00654,R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00196,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP GDHHQS3_k127_4828129_0 1234364.AMSF01000078_gene1824 4.761e-219 688.0 COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales 135614|Xanthomonadales E Cystathionine beta-synthase cysB - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP GDHHQS3_k127_4828129_3 1218076.BAYB01000001_gene58 4.299e-06 53.0 COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,2VVX0@28216|Betaproteobacteria,1KACR@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF465) - - - ko:K09794 - - - - ko00000 - - - DUF465 GDHHQS3_k127_4828129_2 686578.AFFX01000009_gene2935 1.373e-30 124.0 COG2885@1|root,COG2885@2|Bacteria,1N97C@1224|Proteobacteria,1S8TJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - DUF4398,OmpA GDHHQS3_k127_4839406_6 909663.KI867150_gene786 5.454e-31 128.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales 28221|Deltaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 4.1.1.7 ko:K01576 ko00627,ko01120,map00627,map01120 - R01764,R02672 RC00595 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_4839406_4 909663.KI867150_gene786 8.132e-89 314.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales 28221|Deltaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 4.1.1.7 ko:K01576 ko00627,ko01120,map00627,map01120 - R01764,R02672 RC00595 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_4839406_8 926566.Terro_3907 6.388e-09 61.0 COG2010@1|root,COG2010@2|Bacteria,3Y78Q@57723|Acidobacteria,2JM8T@204432|Acidobacteriia 2|Bacteria C Cytochrome c - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_4839406_3 1134413.ANNK01000087_gene253 2.533e-94 327.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,1ZR0K@1386|Bacillus 91061|Bacilli H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 ko:K01612 ko00627,ko01120,ko01220,map00627,map01120,map01220 - R01238 RC00391 ko00000,ko00001,ko01000 - - - UbiD GDHHQS3_k127_4839406_7 1120949.KB903315_gene208 1.348e-29 132.0 COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria,4DESX@85008|Micromonosporales 201174|Actinobacteria K AraC-binding-like domain - - - - - - - - - - - - AraC_binding_2,HTH_18 GDHHQS3_k127_4839406_2 1123279.ATUS01000001_gene1689 1.166e-98 337.0 COG2807@1|root,COG2807@2|Bacteria,1QUSV@1224|Proteobacteria,1T3IC@1236|Gammaproteobacteria,1JC14@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_4839406_5 497964.CfE428DRAFT_3867 1.133e-35 139.0 COG1977@1|root,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process - - 2.7.7.80,2.8.1.11 ko:K03636,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - ThiS GDHHQS3_k127_4839406_0 1382359.JIAL01000001_gene657 5.171e-212 663.0 COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia 204432|Acidobacteriia S cellulose binding - - - - - - - - - - - - BNR GDHHQS3_k127_4839406_1 1210884.HG799465_gene11770 3.373e-116 384.0 COG0476@1|root,COG0476@2|Bacteria,2IWVB@203682|Planctomycetes 203682|Planctomycetes H involved in molybdopterin and thiamine biosynthesis family 2 - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF GDHHQS3_k127_4841896_2 1476583.DEIPH_ctg025orf0105 1.677e-79 271.0 COG2521@1|root,COG2521@2|Bacteria 2|Bacteria AJ methyltransferase - - 2.1.1.113,2.1.1.72 ko:K00590,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - Methyltransf_11,N6_N4_Mtase GDHHQS3_k127_4841896_1 1298593.TOL_1245 2.131e-109 388.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales 135619|Oceanospirillales D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 GDHHQS3_k127_4841896_0 1121937.AUHJ01000015_gene144 5.068e-275 858.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,463XW@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GDHHQS3_k127_4842024_1 1535422.ND16A_1676 0.0001591 47.0 COG3609@1|root,COG3609@2|Bacteria,1N9NJ@1224|Proteobacteria,1SCVS@1236|Gammaproteobacteria,2Q884@267889|Colwelliaceae 1236|Gammaproteobacteria K Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH - - - ko:K07746 - - - - ko00000,ko02048 - - - ParD_antitoxin GDHHQS3_k127_4842024_0 314285.KT71_02627 2.459e-95 335.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_4844199_6 1248916.ANFY01000003_gene1040 5.848e-50 185.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2K3D5@204457|Sphingomonadales 204457|Sphingomonadales C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN GDHHQS3_k127_4844199_5 1390370.O203_19190 2.306e-64 226.0 COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,1SGA2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin GDHHQS3_k127_4844199_12 319224.Sputcn32_0590 1.617e-05 50.0 COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,2QAZ7@267890|Shewanellaceae 1236|Gammaproteobacteria C Belongs to the catalase family katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - iECO26_1355.ECO26_2506 Catalase,Catalase-rel,DJ-1_PfpI GDHHQS3_k127_4844199_9 1122185.N792_07155 3.531e-36 141.0 COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,1X490@135614|Xanthomonadales 135614|Xanthomonadales P Serves to protect cells from the toxic effects of hydrogen peroxide katE - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI GDHHQS3_k127_4844199_8 319224.Sputcn32_0590 4.473e-41 155.0 COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,2QAZ7@267890|Shewanellaceae 1236|Gammaproteobacteria C Belongs to the catalase family katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - iECO26_1355.ECO26_2506 Catalase,Catalase-rel,DJ-1_PfpI GDHHQS3_k127_4844199_10 1158165.KB898872_gene1121 2.63e-27 112.0 COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,1WZZG@135613|Chromatiales 135613|Chromatiales C Serves to protect cells from the toxic effects of hydrogen peroxide - - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI GDHHQS3_k127_4844199_7 1403819.BATR01000016_gene492 6.564e-50 186.0 COG3861@1|root,COG3861@2|Bacteria,46YHK@74201|Verrucomicrobia,2IVQ4@203494|Verrucomicrobiae 203494|Verrucomicrobiae S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - - - - - - - - - - - GDHHQS3_k127_4844199_3 1245471.PCA10_07180 1.623e-73 254.0 COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,1S488@1236|Gammaproteobacteria,1YFC5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2 GDHHQS3_k127_4844199_1 1279015.KB908455_gene1268 4.779e-110 362.0 COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1Y5BU@135624|Aeromonadales 135624|Aeromonadales K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2 GDHHQS3_k127_4844199_2 211165.AJLN01000085_gene1672 9.82e-75 257.0 COG0605@1|root,COG0605@2|Bacteria,1G0VH@1117|Cyanobacteria,1JJAI@1189|Stigonemataceae 1117|Cyanobacteria P Iron/manganese superoxide dismutases, alpha-hairpin domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N GDHHQS3_k127_4844199_4 1454004.AW11_00951 7.729e-67 239.0 COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria 28216|Betaproteobacteria K crp fnr family - - - - - - - - - - - - HTH_Crp_2 GDHHQS3_k127_4844199_0 1232410.KI421422_gene2063 9.708e-187 602.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43S1W@69541|Desulfuromonadales 28221|Deltaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS GDHHQS3_k127_4844199_11 485918.Cpin_3605 1.192e-09 67.0 COG0250@1|root,COG0250@2|Bacteria,4NUBQ@976|Bacteroidetes,1ITIT@117747|Sphingobacteriia 976|Bacteroidetes K Transcription termination factor nusG - - - - - - - - - - - - NusG GDHHQS3_k127_4864805_4 1535422.ND16A_1733 1.623e-42 162.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase,DUF3471 GDHHQS3_k127_4864805_0 1163409.UUA_03463 2.499e-299 929.0 COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1RZQR@1236|Gammaproteobacteria,1XCEP@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type multidrug transport system ATPase and permease - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran GDHHQS3_k127_4864805_2 857087.Metme_1914 5.267e-91 326.0 COG0419@1|root,COG3264@1|root,COG0419@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales 135618|Methylococcales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel GDHHQS3_k127_4864805_1 1550073.JROH01000072_gene2819 5.89e-128 432.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales 204457|Sphingomonadales J Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase GDHHQS3_k127_4864805_3 1122137.AQXF01000001_gene2778 6.417e-60 231.0 2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 GDHHQS3_k127_4876760_8 1232437.KL662057_gene3898 4.88e-38 147.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K08357 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding GDHHQS3_k127_4876760_3 1232437.KL662057_gene3899 2.666e-86 289.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2MNMB@213118|Desulfobacterales 28221|Deltaproteobacteria C 4Fe-4S dicluster domain - - - ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Fer4_11,Fer4_4 GDHHQS3_k127_4876760_6 1232437.KL662057_gene3900 7.054e-40 160.0 COG3301@1|root,COG3301@2|Bacteria,1N6TR@1224|Proteobacteria 1224|Proteobacteria P DMSO reductase anchor subunit (DmsC) - - - - - - - - - - - - NrfD GDHHQS3_k127_4876760_2 1121374.KB891589_gene75 1.358e-155 507.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_4876760_1 443598.AUFA01000022_gene3254 1.013e-170 551.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,3JXYK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase - - 1.1.99.3 ko:K06151 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_4876760_5 1121374.KB891589_gene74 1.47e-43 165.0 2E7KM@1|root,3322M@2|Bacteria,1N7XR@1224|Proteobacteria,1SQEB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_4876760_10 1121374.KB891592_gene2908 1.367e-25 117.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1SD0V@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c class I - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_4876760_12 743299.Acife_0041 9.972e-18 85.0 COG4113@1|root,COG4113@2|Bacteria,1RIR6@1224|Proteobacteria,1T962@1236|Gammaproteobacteria,2NDXX@225057|Acidithiobacillales 225057|Acidithiobacillales S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN GDHHQS3_k127_4876760_9 671143.DAMO_0771 4.078e-35 135.0 COG3514@1|root,COG3514@2|Bacteria 2|Bacteria S BrnA antitoxin of type II toxin-antitoxin system - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - BrnA_antitoxin GDHHQS3_k127_4876760_11 1125863.JAFN01000001_gene2242 3.934e-23 102.0 COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,42VRN@68525|delta/epsilon subdivisions,2WS04@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox GDHHQS3_k127_4876760_7 56107.Cylst_0051 4.856e-38 145.0 COG4115@1|root,COG4115@2|Bacteria,1G9S6@1117|Cyanobacteria,1HPFI@1161|Nostocales 1117|Cyanobacteria S TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family - - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin GDHHQS3_k127_4876760_13 314285.KT71_02822 3.286e-17 88.0 COG5472@1|root,COG5472@2|Bacteria 2|Bacteria S Small integral membrane protein - - - - - - - - - - - - DUF2165 GDHHQS3_k127_4876760_4 1122604.JONR01000034_gene418 5.641e-46 170.0 295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_4876760_0 469383.Cwoe_3870 9.22e-205 657.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS94@84995|Rubrobacteria 201174|Actinobacteria C xanthine dehydrogenase, a b hammerhead - - 1.2.5.3,1.5.99.4 ko:K03520,ko:K19820 ko00760,ko01120,map00760,map01120 M00810 R02860,R07946,R11168 RC00589,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_4888876_3 118166.JH976537_gene974 0.0001812 44.0 COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria,1HCPC@1150|Oscillatoriales 1117|Cyanobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin GDHHQS3_k127_4888876_0 1226994.AMZB01000103_gene1569 8.711e-164 538.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1YIHF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria CG PQQ-like domain - - 1.1.2.8,1.1.5.5,1.1.9.1 ko:K00114,ko:K17760,ko:K22473 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285,R09479 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 GDHHQS3_k127_4888876_1 443143.GM18_4429 3.721e-69 240.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA - - ko:K06883 - - - - ko00000 - - - Arf,Ras GDHHQS3_k127_4960546_0 550540.Fbal_3188 3.129e-99 342.0 COG0369@1|root,COG0369@2|Bacteria,1MWYV@1224|Proteobacteria,1S126@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ GO:0000166,GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016667,GO:0016668,GO:0032553,GO:0032991,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - iECO26_1355.ECO26_3835,iECSE_1348.ECSE_3020,iECW_1372.ECW_m2972,iEKO11_1354.EKO11_1004,iEcE24377_1341.EcE24377A_3066,iEcolC_1368.EcolC_0948,iWFL_1372.ECW_m2972 FAD_binding_1,Flavodoxin_1,NAD_binding_1 GDHHQS3_k127_4960546_1 686340.Metal_3669 1.005e-28 120.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XG35@135618|Methylococcales 135618|Methylococcales CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - - - - - - - - - - FAD_binding_3 GDHHQS3_k127_496647_0 1123073.KB899243_gene829 3.539e-243 797.0 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1X3GZ@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyl transferase - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glycos_transf_2 GDHHQS3_k127_4971688_1 1123377.AUIV01000010_gene2195 2.005e-87 296.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1X2ZH@135614|Xanthomonadales 135614|Xanthomonadales J Involved in the processing of the 5'end of 16S rRNA rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 GDHHQS3_k127_4971688_5 1283300.ATXB01000001_gene1866 2.09e-53 194.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XEYD@135618|Methylococcales 135618|Methylococcales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf GDHHQS3_k127_4971688_4 1396858.Q666_09000 2.165e-55 198.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,466GK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase GDHHQS3_k127_4971688_6 1158165.KB898880_gene1517 1.832e-34 136.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales 135613|Chromatiales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS GDHHQS3_k127_4971688_3 472759.Nhal_0541 1.356e-60 220.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales 135613|Chromatiales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GDHHQS3_k127_4971688_2 498211.CJA_0452 3.346e-68 244.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1FGH0@10|Cellvibrio 1236|Gammaproteobacteria L DNA polymerase III, delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta GDHHQS3_k127_4971688_7 472759.Nhal_0538 5.24e-18 90.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales 135613|Chromatiales M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE GDHHQS3_k127_4971688_0 1384054.N790_09415 0.0 1087.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1X3DK@135614|Xanthomonadales 135614|Xanthomonadales J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 GDHHQS3_k127_4973942_6 1502770.JQMG01000001_gene1696 9.024e-14 72.0 2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,2VR76@28216|Betaproteobacteria,2KMVQ@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_4973942_1 1122137.AQXF01000003_gene1995 0.0 1058.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C GDHHQS3_k127_4973942_7 472759.Nhal_2867 0.0002029 53.0 2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,1X1CC@135613|Chromatiales 135613|Chromatiales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV GDHHQS3_k127_4973942_0 1500893.JQNB01000001_gene2084 0.0 1221.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1X4J8@135614|Xanthomonadales 135614|Xanthomonadales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF GDHHQS3_k127_4973942_3 1122134.KB893650_gene156 3.148e-117 386.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1XIV0@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus GDHHQS3_k127_4973942_2 1049564.TevJSym_at00120 5.9e-133 437.0 COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,1RPND@1236|Gammaproteobacteria,1J945@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S TraB family traB - - - - - - - - - - - TraB GDHHQS3_k127_4973942_5 1122134.KB893650_gene1507 2.871e-14 76.0 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1XMTM@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - GDHHQS3_k127_4973942_4 1166948.JPZL01000002_gene1647 3.324e-62 225.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XHIQ@135619|Oceanospirillales 135619|Oceanospirillales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase GDHHQS3_k127_4994171_2 1122599.AUGR01000024_gene1368 2.782e-147 478.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XH8T@135619|Oceanospirillales 135619|Oceanospirillales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN GDHHQS3_k127_4994171_8 396588.Tgr7_3210 6.792e-22 97.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1WYU8@135613|Chromatiales 135613|Chromatiales J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p GDHHQS3_k127_4994171_3 767434.Fraau_2619 9.338e-143 460.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1X3H0@135614|Xanthomonadales 135614|Xanthomonadales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obgE - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 GDHHQS3_k127_4994171_7 740709.A10D4_03070 2.341e-37 141.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,2QGB8@267893|Idiomarinaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 GDHHQS3_k127_4994171_6 1049564.TevJSym_aa00520 6.963e-42 156.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1J6G6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p GDHHQS3_k127_4994171_0 1123253.AUBD01000007_gene615 0.0 1483.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1X45Q@135614|Xanthomonadales 135614|Xanthomonadales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran GDHHQS3_k127_4994171_9 1384056.N787_05120 1.072e-13 77.0 COG2847@1|root,COG2847@2|Bacteria,1NDCJ@1224|Proteobacteria,1SG2J@1236|Gammaproteobacteria,1X86E@135614|Xanthomonadales 135614|Xanthomonadales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC GDHHQS3_k127_4994171_1 523791.Kkor_1536 2.277e-166 537.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 GDHHQS3_k127_4994171_4 1123253.AUBD01000007_gene619 1.904e-63 226.0 COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,1RRTJ@1236|Gammaproteobacteria,1X44B@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 GDHHQS3_k127_4994171_5 1231391.AMZF01000025_gene1417 7.273e-43 159.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,3T2UC@506|Alcaligenaceae 28216|Betaproteobacteria P Sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese GDHHQS3_k127_5035976_6 314270.RB2083_766 1.782e-17 84.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,3ZHH4@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_N,GST_N_3 GDHHQS3_k127_5035976_0 1123401.JHYQ01000017_gene2515 0.0 1735.0 COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,1T41W@1236|Gammaproteobacteria 1236|Gammaproteobacteria C catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second - - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA GDHHQS3_k127_5035976_1 762376.AXYL_03506 1.698e-115 387.0 COG0154@1|root,COG0154@2|Bacteria,1MUKC@1224|Proteobacteria,2VK9V@28216|Betaproteobacteria,3T8XI@506|Alcaligenaceae 28216|Betaproteobacteria J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase GDHHQS3_k127_5035976_2 697282.Mettu_2857 2.668e-91 308.0 COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,1XGHM@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF541) - - - - - - - - - - - - SIMPL GDHHQS3_k127_5035976_5 1122176.KB903571_gene4786 1.23e-22 113.0 COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - DUF1736,TPR_16,TPR_2,TPR_8 GDHHQS3_k127_5035976_7 521674.Plim_3716 1.996e-07 56.0 COG0476@1|root,COG0476@2|Bacteria,2IWVB@203682|Planctomycetes 203682|Planctomycetes H involved in molybdopterin and thiamine biosynthesis family 2 - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF GDHHQS3_k127_5041238_0 1123073.KB899242_gene1137 4.906e-191 612.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1X3V7@135614|Xanthomonadales 135614|Xanthomonadales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon GDHHQS3_k127_5041238_3 1304875.JAFZ01000001_gene1514 8.163e-28 122.0 COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria,3TCC8@508458|Synergistetes 508458|Synergistetes MOP NlpE C-terminal OB domain - - - - - - - - - - - - META,NlpE,NlpE_C GDHHQS3_k127_5041238_2 187272.Mlg_0268 1.17e-51 189.0 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1WZFF@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 GDHHQS3_k127_5041238_4 686340.Metal_2390 6.994e-17 83.0 COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1XFAF@135618|Methylococcales 135618|Methylococcales S Putative member of DMT superfamily (DUF486) - - - ko:K09922 - - - - ko00000 - - - DMT_6 GDHHQS3_k127_5041238_1 204669.Acid345_3656 2.676e-90 306.0 COG3191@1|root,COG3191@2|Bacteria 2|Bacteria EQ aminopeptidase activity dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 GDHHQS3_k127_5042816_1 740709.A10D4_07947 1.229e-146 468.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,2QF9C@267893|Idiomarinaceae 1236|Gammaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N GDHHQS3_k127_5042816_2 1121013.P873_13335 2.321e-116 381.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1X3U6@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt GDHHQS3_k127_5042816_0 1380387.JADM01000004_gene2844 2.197e-245 763.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XIMC@135619|Oceanospirillales 135619|Oceanospirillales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N GDHHQS3_k127_5042816_3 1121940.AUDZ01000013_gene609 1.295e-15 78.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1XK0R@135619|Oceanospirillales 135619|Oceanospirillales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N GDHHQS3_k127_5070452_3 314278.NB231_03947 1.064e-10 64.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1WZHE@135613|Chromatiales 135613|Chromatiales NU pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_5070452_2 857087.Metme_2145 7.168e-28 119.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1XFP2@135618|Methylococcales 135618|Methylococcales U Type IV minor pilin ComP, DNA uptake sequence receptor - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl GDHHQS3_k127_5070452_0 1283300.ATXB01000001_gene78 4.418e-43 166.0 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1XFKE@135618|Methylococcales 135618|Methylococcales NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl GDHHQS3_k127_509629_5 1168065.DOK_12301 5.313e-28 121.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1J9DQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold fldW - 4.1.1.45,4.2.1.83 ko:K03392,ko:K10220 ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120 M00038 R04323,R04478 RC00498,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 GDHHQS3_k127_509629_3 1121022.ABENE_11255 1.115e-72 268.0 COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2TVBS@28211|Alphaproteobacteria,2KIQV@204458|Caulobacterales 204458|Caulobacterales I Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,NAD_binding_2 GDHHQS3_k127_509629_0 1168065.DOK_12291 4.127e-157 502.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1J5BN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria galD GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF GDHHQS3_k127_509629_2 1168065.DOK_12286 3.553e-102 337.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,1J8VD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG0684 Demethylmenaquinone methyltransferase fldZ - 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 - - - RraA-like GDHHQS3_k127_509629_1 1121374.KB891585_gene2196 1.197e-115 385.0 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,1RWPD@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K16516 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate GDHHQS3_k127_509629_4 1187851.A33M_3204 9.587e-41 157.0 COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,2UDB6@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 GDHHQS3_k127_5097887_1 1265313.HRUBRA_01045 1.515e-160 516.0 2CHDJ@1|root,2Z8E7@2|Bacteria,1MXGG@1224|Proteobacteria,1RQ5A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1864) prnB - - ko:K19981 ko00404,ko01130,map00404,map01130 M00790 R11105 RC03359 ko00000,ko00001,ko00002 - - - DUF1864 GDHHQS3_k127_5097887_2 747365.Thena_1145 5.111e-09 70.0 COG0243@1|root,COG0243@2|Bacteria,1V2XY@1239|Firmicutes,24GWZ@186801|Clostridia,42GHT@68295|Thermoanaerobacterales 186801|Clostridia C Molybdopterin oxidoreductase Fe4S4 domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4 GDHHQS3_k127_5097887_0 1232437.KL662057_gene3898 4.1e-246 781.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K08357 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding GDHHQS3_k127_5098016_0 1122135.KB893134_gene3134 3.182e-152 497.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1042 Acyl-CoA synthetase (NDP forming) - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig GDHHQS3_k127_5098016_1 1122135.KB893134_gene3135 3.175e-114 378.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.99 ko:K09472 ko00330,ko01100,map00330,map01100 M00136 R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_5102444_4 62928.azo0048 8.876e-85 290.0 COG4676@1|root,COG4676@2|Bacteria,1R4HE@1224|Proteobacteria,2VP30@28216|Betaproteobacteria,2KXYF@206389|Rhodocyclales 206389|Rhodocyclales S Uncharacterized protein conserved in bacteria (DUF2135) - - - - - - - - - - - - DUF2135 GDHHQS3_k127_5102444_5 1472716.KBK24_0125300 3.517e-75 260.0 COG4676@1|root,COG4676@2|Bacteria,1R801@1224|Proteobacteria,2VPGN@28216|Betaproteobacteria,1K4IF@119060|Burkholderiaceae 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2135) - - - - - - - - - - - - DUF2135 GDHHQS3_k127_5102444_1 522306.CAP2UW1_3998 1.428e-122 412.0 COG5445@1|root,COG5445@2|Bacteria,1QBHH@1224|Proteobacteria,2VM12@28216|Betaproteobacteria 28216|Betaproteobacteria S Stage II sporulation protein - - - - - - - - - - - - DUF2300,SpoIID GDHHQS3_k127_5102444_0 29581.BW37_03584 0.0 1340.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VMEI@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,Thiol-ester_cl GDHHQS3_k127_5102444_6 1031711.RSPO_c00464 1.151e-70 246.0 COG3234@1|root,COG3234@2|Bacteria,1R6VA@1224|Proteobacteria,2VKIF@28216|Betaproteobacteria,1K3WU@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1175) - - - ko:K09934 - - - - ko00000 - - - DUF1175 GDHHQS3_k127_5102444_3 29581.BW37_03586 2.149e-85 303.0 COG4685@1|root,COG4685@2|Bacteria,1MY31@1224|Proteobacteria,2VNU8@28216|Betaproteobacteria 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2138) - - - - - - - - - - - - DUF2138 GDHHQS3_k127_5102444_7 1323663.AROI01000027_gene1584 1.235e-06 51.0 COG2963@1|root,COG2963@2|Bacteria,1N28U@1224|Proteobacteria,1S9BK@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GDHHQS3_k127_5102444_2 1123256.KB907940_gene198 5.353e-104 350.0 2BQ5T@1|root,32J08@2|Bacteria,1NV57@1224|Proteobacteria,1SNJR@1236|Gammaproteobacteria,1X7WY@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_5121165_0 930169.B5T_01008 1.5e-134 436.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XHUY@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N GDHHQS3_k127_5121165_1 1234364.AMSF01000053_gene1332 8.804e-103 338.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1X3W3@135614|Xanthomonadales 135614|Xanthomonadales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C GDHHQS3_k127_512433_2 1122185.N792_06685 2.195e-21 93.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1X3VD@135614|Xanthomonadales 135614|Xanthomonadales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 GDHHQS3_k127_512433_1 243233.MCA1876 9.543e-142 458.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XE2G@135618|Methylococcales 135618|Methylococcales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metAS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS GDHHQS3_k127_512433_0 1121935.AQXX01000139_gene3072 4.875e-210 659.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1XIBP@135619|Oceanospirillales 135619|Oceanospirillales E O-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP GDHHQS3_k127_512433_3 330214.NIDE1164 3.163e-18 86.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - GerE,Response_reg GDHHQS3_k127_5293321_1 472759.Nhal_3832 1.551e-139 463.0 COG5492@1|root,COG5492@2|Bacteria,1QXT5@1224|Proteobacteria,1T4IG@1236|Gammaproteobacteria,1X2RJ@135613|Chromatiales 135613|Chromatiales N domain, Protein - - - - - - - - - - - - - GDHHQS3_k127_5293321_0 472759.Nhal_3833 5.109e-202 660.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,1X0CV@135613|Chromatiales 135613|Chromatiales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_5293321_2 382245.ASA_1522 1.039e-76 265.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1Y42Q@135624|Aeromonadales 135624|Aeromonadales P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU GDHHQS3_k127_5293321_3 1123073.KB899242_gene1472 1.225e-51 198.0 COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,1SASN@1236|Gammaproteobacteria,1X577@135614|Xanthomonadales 135614|Xanthomonadales M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY GDHHQS3_k127_5302450_2 1122185.N792_07260 1.114e-40 152.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1X7QC@135614|Xanthomonadales 135614|Xanthomonadales S BolA family transcriptional regulator yciI - - ko:K09780 - - - - ko00000 - - - YCII GDHHQS3_k127_5302450_3 1045855.DSC_07805 2.057e-25 112.0 COG0271@1|root,COG0271@2|Bacteria,1QCDM@1224|Proteobacteria,1RTFD@1236|Gammaproteobacteria,1X7ES@135614|Xanthomonadales 135614|Xanthomonadales T Belongs to the BolA IbaG family - - - ko:K05527 - - - - ko00000,ko03000 - - - BolA GDHHQS3_k127_5302450_1 631362.Thi970DRAFT_03684 3.336e-59 207.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales 135613|Chromatiales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF GDHHQS3_k127_5302450_0 1049564.TevJSym_ah00850 9.726e-143 469.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1J4IV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge GDHHQS3_k127_5338755_2 323848.Nmul_A1150 4.052e-102 336.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales 28216|Betaproteobacteria CEH PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 GDHHQS3_k127_5338755_3 404589.Anae109_3693 8.242e-47 184.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2Z198@29|Myxococcales 28221|Deltaproteobacteria I Alpha/beta hydrolase family agmH - - - - - - - - - - - Hydrolase_4 GDHHQS3_k127_5338755_0 717605.Theco_0520 1.19e-190 607.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,26QJT@186822|Paenibacillaceae 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N GDHHQS3_k127_5338755_1 1415780.JPOG01000001_gene1824 1.536e-188 607.0 COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1X9CV@135614|Xanthomonadales 135614|Xanthomonadales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - - - - - - - - - - SBP_bac_5 GDHHQS3_k127_5338755_4 1415780.JPOG01000001_gene1823 1.324e-39 155.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1S4HN@1236|Gammaproteobacteria,1X9SZ@135614|Xanthomonadales 135614|Xanthomonadales EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 GDHHQS3_k127_5342663_0 1187851.A33M_0168 3.451e-161 523.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding pyrK - 1.16.1.3,1.18.1.2,1.19.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.1.41,1.5.8.1,1.5.8.2 ko:K00207,ko:K00219,ko:K00317,ko:K00528,ko:K02293,ko:K02823,ko:K05368,ko:K10797 ko00240,ko00360,ko00410,ko00680,ko00740,ko00770,ko00860,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00680,map00740,map00770,map00860,map00906,map00983,map01100,map01110,map01120,map01200 M00046,M00097 R00097,R00978,R01415,R01588,R02252,R02511,R04786,R04787,R05705,R07510,R08226,R09652,R09653,R09654,R10159 RC00072,RC00123,RC00126,RC00185,RC00220,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC03092,RC03093 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase,DHODB_Fe-S_bind,NAD_binding_1,Pyr_redox_2 GDHHQS3_k127_5342663_3 523791.Kkor_0990 6.413e-56 204.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XJNB@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA GDHHQS3_k127_5342663_6 1283300.ATXB01000001_gene733 8.293e-09 61.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XFQI@135618|Methylococcales 135618|Methylococcales S STAS domain - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 GDHHQS3_k127_5342663_5 767434.Fraau_0417 7.483e-31 130.0 COG2854@1|root,COG2854@2|Bacteria,1R4I3@1224|Proteobacteria,1RY1E@1236|Gammaproteobacteria,1XBZ7@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC GDHHQS3_k127_5342663_4 1249627.D779_0309 5.058e-43 162.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1WXYG@135613|Chromatiales 135613|Chromatiales Q PFAM Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD GDHHQS3_k127_5342663_2 1123073.KB899241_gene2050 2.981e-66 236.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1X51X@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents permease component yrbE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE GDHHQS3_k127_5342663_1 1049564.TevJSym_ag00260 1.868e-93 315.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1J8TI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q ABC transporter mlaF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran GDHHQS3_k127_5343976_2 1163408.UU9_02973 4.249e-43 162.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S76U@1236|Gammaproteobacteria,1X5ZX@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ GDHHQS3_k127_5343976_1 1318628.MARLIPOL_14290 2.479e-98 329.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 GDHHQS3_k127_5343976_3 1045855.DSC_02850 1.911e-13 74.0 COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SEN9@1236|Gammaproteobacteria,1X7JK@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL GDHHQS3_k127_5343976_0 713586.KB900536_gene1379 8.765e-114 379.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase GDHHQS3_k127_5366496_0 1249627.D779_2312 7.521e-130 425.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXUN@135613|Chromatiales 135613|Chromatiales P TrkA-C domain - - - - - - - - - - - - CitMHS,TrkA_C GDHHQS3_k127_5366496_2 686340.Metal_0957 6.935e-22 105.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,1XFRS@135618|Methylococcales 135618|Methylococcales L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG GDHHQS3_k127_5366496_1 1129374.AJE_03221 4.017e-42 162.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,464GK@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins ampC - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase GDHHQS3_k127_5376114_9 765912.Thimo_0714 6.486e-39 147.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA GDHHQS3_k127_5376114_8 492774.JQMB01000004_gene1930 3.001e-45 168.0 COG0346@1|root,COG0346@2|Bacteria,1RH4D@1224|Proteobacteria,2U7GX@28211|Alphaproteobacteria,4BN3V@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_5376114_3 1121015.N789_05605 1.937e-93 325.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1X53G@135614|Xanthomonadales 135614|Xanthomonadales L Nucleotidyltransferase DNA polymerase involved in DNA repair - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS GDHHQS3_k127_5376114_7 62928.azo3955 4.382e-47 178.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,2VUGI@28216|Betaproteobacteria,2KWPG@206389|Rhodocyclales 206389|Rhodocyclales S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K14160 - - - - ko00000,ko03400 - - - RecA,SulA GDHHQS3_k127_5376114_5 713586.KB900536_gene826 3.103e-70 250.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 GDHHQS3_k127_5376114_2 1128427.KB904821_gene838 1.416e-96 333.0 COG0591@1|root,COG0591@2|Bacteria,1G2XQ@1117|Cyanobacteria,1HA58@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF GDHHQS3_k127_5376114_0 1121448.DGI_3104 4.984e-125 420.0 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2WJGZ@28221|Deltaproteobacteria,2M9Y5@213115|Desulfovibrionales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 GDHHQS3_k127_5376114_6 525897.Dbac_2637 5.054e-52 189.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2WNI1@28221|Deltaproteobacteria,2MBH5@213115|Desulfovibrionales 28221|Deltaproteobacteria S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA GDHHQS3_k127_5376114_4 765910.MARPU_08750 5.94e-81 276.0 COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,1S1WW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM conserved - - - - - - - - - - - - DUF2461 GDHHQS3_k127_5376114_10 1163409.UUA_07718 1.778e-35 143.0 COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1X64R@135614|Xanthomonadales 135614|Xanthomonadales M Outer membrane lipoprotein slp - - ko:K07285 - - - - ko00000 - - - Slp GDHHQS3_k127_5376114_1 1385517.N800_14350 2.316e-123 419.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1X3BD@135614|Xanthomonadales 135614|Xanthomonadales E Transglutaminase/protease-like homologues - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core GDHHQS3_k127_5376114_11 1349767.GJA_4067 1.027e-10 63.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,473SB@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 GDHHQS3_k127_5457754_3 929712.KI912613_gene624 1.843e-20 93.0 COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4CPAN@84995|Rubrobacteria 84995|Rubrobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase GDHHQS3_k127_5457754_1 1234364.AMSF01000037_gene208 2.284e-90 302.0 COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,1RS8B@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Nitroreductase - - - - - - - - - - - - Nitroreductase GDHHQS3_k127_5457754_0 1535422.ND16A_1642 8.389e-290 904.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,2Q7WG@267889|Colwelliaceae 1236|Gammaproteobacteria O Peptidase family M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_5457754_2 710687.KI912270_gene4057 2.613e-76 273.0 COG0160@1|root,COG0160@2|Bacteria,2H3YC@201174|Actinobacteria,23C7F@1762|Mycobacteriaceae 201174|Actinobacteria E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 GDHHQS3_k127_5471236_5 342610.Patl_3353 2.217e-09 63.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,2PZX8@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O peptidase M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_5471236_3 1265503.KB905168_gene1401 7.919e-64 229.0 COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,2Q70T@267889|Colwelliaceae 1236|Gammaproteobacteria G Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase GDHHQS3_k127_5471236_4 1335757.SPICUR_01325 3.542e-29 124.0 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_5471236_2 1121918.ARWE01000001_gene2703 3.023e-77 275.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH GDHHQS3_k127_5471236_6 243265.plu0423 7.052e-09 63.0 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX GDHHQS3_k127_5471236_0 316274.Haur_2807 5.139e-186 587.0 COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,3764B@32061|Chloroflexia 32061|Chloroflexia E PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GDHHQS3_k127_5471236_1 392499.Swit_4257 3.113e-138 463.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U0W6@28211|Alphaproteobacteria,2K2Q5@204457|Sphingomonadales 204457|Sphingomonadales P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_5552568_6 1380358.JADJ01000003_gene4616 3.33e-37 156.0 2CA5V@1|root,2Z9I7@2|Bacteria,1R50M@1224|Proteobacteria,1RQS7@1236|Gammaproteobacteria,1XK87@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - GDHHQS3_k127_5552568_0 765914.ThisiDRAFT_0190 6.812e-190 607.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB GDHHQS3_k127_5552568_5 765914.ThisiDRAFT_0189 8.793e-46 166.0 COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SA8D@1236|Gammaproteobacteria,1X1J6@135613|Chromatiales 135613|Chromatiales C 4TM region of pyridine nucleotide transhydrogenase, mitoch - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM GDHHQS3_k127_5552568_1 396588.Tgr7_0268 9.875e-130 425.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1WWTF@135613|Chromatiales 135613|Chromatiales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM GDHHQS3_k127_5552568_4 765912.Thimo_3699 5.253e-71 251.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales 135613|Chromatiales JM PFAM Nucleotidyl transferase - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase GDHHQS3_k127_5552568_3 1215092.PA6_037_00320 1.046e-78 274.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1YDF8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phosphotransferase enzyme family - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH GDHHQS3_k127_5552568_7 913325.N799_01730 6.297e-35 138.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator - - - - - - - - - - - - Rrf2 GDHHQS3_k127_5552568_2 472759.Nhal_0688 1.268e-109 359.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly protein SufB - - - ko:K09014 - - - - ko00000 - - - UPF0051 GDHHQS3_k127_5559726_0 1283300.ATXB01000001_gene1978 1.107e-116 384.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XE9P@135618|Methylococcales 1236|Gammaproteobacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide JD73_00825 - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_5559726_3 1408419.JHYG01000002_gene1070 1.396e-07 56.0 COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2JUKH@204441|Rhodospirillales 204441|Rhodospirillales IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding GDHHQS3_k127_5559726_1 1500890.JQNL01000001_gene245 9.347e-71 252.0 COG0702@1|root,COG0702@2|Bacteria,1R2KN@1224|Proteobacteria,1T5SD@1236|Gammaproteobacteria,1XDE2@135614|Xanthomonadales 135614|Xanthomonadales GM NmrA-like family - - - - - - - - - - - - Epimerase GDHHQS3_k127_5559726_2 1304275.C41B8_04656 7.845e-33 131.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II JD73_00810 - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C_2,PP-binding GDHHQS3_k127_5579439_2 743720.Psefu_3674 3.554e-48 178.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1YV1C@136845|Pseudomonas putida group 1236|Gammaproteobacteria P ABC transporter lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C GDHHQS3_k127_5579439_5 631362.Thi970DRAFT_02467 7.273e-07 59.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1WYD5@135613|Chromatiales 135613|Chromatiales T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA,SH3_3 GDHHQS3_k127_5579439_4 1120953.AUBH01000004_gene3061 5.499e-08 62.0 COG3117@1|root,COG3117@2|Bacteria,1RA1Y@1224|Proteobacteria,1SDZE@1236|Gammaproteobacteria,4675P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03015,iECBD_1354.ECBD_0543,iECB_1328.ECB_03064,iECD_1391.ECD_03064 LptC GDHHQS3_k127_5579439_1 1121403.AUCV01000028_gene2458 2.347e-50 184.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WP0X@28221|Deltaproteobacteria,2MPUR@213118|Desulfobacterales 28221|Deltaproteobacteria S haloacid dehalogenase-like hydrolase kdsC - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_3 GDHHQS3_k127_5579439_0 105559.Nwat_0300 1.763e-131 426.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales 135613|Chromatiales M Arabinose 5-phosphate isomerase - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS GDHHQS3_k127_5579439_3 1442599.JAAN01000014_gene3556 5.145e-23 100.0 COG5007@1|root,COG5007@2|Bacteria,1R3MK@1224|Proteobacteria,1SE4M@1236|Gammaproteobacteria,1X7EE@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the BolA IbaG family SN15_13775 - - - - - - - - - - - BolA GDHHQS3_k127_559038_3 1123073.KB899241_gene2821 8.047e-23 100.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1X6IK@135614|Xanthomonadales 135614|Xanthomonadales O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA GDHHQS3_k127_559038_0 94624.Bpet0232 2.909e-224 706.0 COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2VNF9@28216|Betaproteobacteria,3T7US@506|Alcaligenaceae 28216|Betaproteobacteria S protein related to capsule biosynthesis enzymes - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C GDHHQS3_k127_559038_2 1209072.ALBT01000023_gene3995 9.416e-39 145.0 COG1396@1|root,COG1396@2|Bacteria,1NARB@1224|Proteobacteria,1SF0Q@1236|Gammaproteobacteria,1FIF3@10|Cellvibrio 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 GDHHQS3_k127_559038_1 1121015.N789_07665 5.303e-76 265.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1T04X@1236|Gammaproteobacteria,1XCYU@135614|Xanthomonadales 135614|Xanthomonadales CP Sodium ABC transporter permease - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 GDHHQS3_k127_5612179_6 1159870.KB907784_gene984 5.317e-40 149.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,3T6CU@506|Alcaligenaceae 28216|Betaproteobacteria S Belongs to the LOG family yvdD_1 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox GDHHQS3_k127_5612179_5 247634.GPB2148_2270 2.547e-44 167.0 COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,1JB8F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_5612179_3 1384054.N790_07690 1.155e-55 207.0 COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria,1XCS6@135614|Xanthomonadales 135614|Xanthomonadales M Periplasmic protein TonB links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C GDHHQS3_k127_5612179_1 1384056.N787_12615 1.106e-126 413.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1X3UD@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the prokaryotic GSH synthase family gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N GDHHQS3_k127_5612179_4 1123261.AXDW01000018_gene783 6.125e-50 183.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1X6HP@135614|Xanthomonadales 135614|Xanthomonadales KT response regulator pilG - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg GDHHQS3_k127_5612179_7 1123253.AUBD01000010_gene2096 1.337e-30 127.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1X5IW@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW GDHHQS3_k127_5612179_0 225937.HP15_3516 2.477e-161 532.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465M4@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ GDHHQS3_k127_5612179_2 1234364.AMSF01000055_gene1106 7.08e-108 391.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg GDHHQS3_k127_5622429_2 504472.Slin_1556 5.22e-39 151.0 COG0477@1|root,COG2814@2|Bacteria,4NI75@976|Bacteroidetes,47M13@768503|Cytophagia 976|Bacteroidetes EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,MFS_4,Sugar_tr GDHHQS3_k127_5622429_1 313612.L8106_08051 2.219e-119 403.0 COG3961@1|root,COG3961@2|Bacteria,1G1A5@1117|Cyanobacteria,1H9TP@1150|Oscillatoriales 1117|Cyanobacteria GH Belongs to the TPP enzyme family pdc - 4.1.1.74 ko:K04103 ko00380,ko01100,map00380,map01100 - R01974 RC00506 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_5622429_0 1003200.AXXA_30782 5.435e-144 468.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2VQ15@28216|Betaproteobacteria,3T243@506|Alcaligenaceae 28216|Betaproteobacteria P Organic Anion Transporter Polypeptide (OATP) family - - - - - - - - - - - - MFS_1 GDHHQS3_k127_5624376_1 84531.JMTZ01000038_gene3596 0.0 1266.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N GDHHQS3_k127_5624376_2 1500890.JQNL01000001_gene856 5.615e-175 557.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales 135614|Xanthomonadales I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_5624376_4 1094184.KWO_0121255 1.264e-100 336.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,1SC37@1236|Gammaproteobacteria,1XCHM@135614|Xanthomonadales 135614|Xanthomonadales KQ ArsR family transcriptional regulator - - - - - - - - - - - - HTH_5,Methyltransf_11 GDHHQS3_k127_5624376_0 1286106.MPL1_11008 0.0 1526.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales 72273|Thiotrichales E Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans GDHHQS3_k127_5624376_5 666685.R2APBS1_2244 1.519e-16 88.0 COG3122@1|root,COG3122@2|Bacteria,1P4D6@1224|Proteobacteria,1SGUC@1236|Gammaproteobacteria,1X2Y4@135614|Xanthomonadales 135614|Xanthomonadales S Nucleoprotein polynucleotide-associated enzyme - - - ko:K09912 - - - - ko00000 - - - DUF2058 GDHHQS3_k127_5624376_3 1266914.ATUK01000001_gene826 7.997e-103 340.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1WVWB@135613|Chromatiales 135613|Chromatiales GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase GDHHQS3_k127_5632177_1 1123073.KB899242_gene1206 9.856e-61 217.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1X3PI@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer GDHHQS3_k127_5632177_0 767434.Fraau_3196 1.674e-122 398.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase GDHHQS3_k127_5651042_5 471874.PROSTU_04571 2.171e-40 153.0 COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,3Z8C2@586|Providencia 1236|Gammaproteobacteria F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_0003 GHMP_kinases_C,GHMP_kinases_N GDHHQS3_k127_5651042_1 416269.APL_1499 5.399e-156 503.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1Y7IQ@135625|Pasteurellales 135625|Pasteurellales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N GDHHQS3_k127_5651042_4 743721.Psesu_1753 4.938e-42 159.0 COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09793 - - - - ko00000 - - - DUF456 GDHHQS3_k127_5651042_2 187303.BN69_3503 3.558e-125 408.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,36XYF@31993|Methylocystaceae 28211|Alphaproteobacteria S Polyphosphate kinase 2 (PPK2) ppk2 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 GDHHQS3_k127_5651042_6 317936.Nos7107_5165 2.21e-26 114.0 COG1846@1|root,COG1846@2|Bacteria,1G61S@1117|Cyanobacteria 1117|Cyanobacteria K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 GDHHQS3_k127_5651042_3 1415778.JQMM01000001_gene1373 5.382e-43 160.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1J66X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 GDHHQS3_k127_5651042_0 1236542.BALM01000001_gene338 5.776e-164 526.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,2Q937@267890|Shewanellaceae 1236|Gammaproteobacteria C TIGRFAM glutamate synthase, small subunit gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 GDHHQS3_k127_5657069_0 1120953.AUBH01000006_gene2643 2.347e-104 351.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,46AI8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_5662785_1 1173027.Mic7113_2972 1.646e-75 261.0 COG2008@1|root,COG2008@2|Bacteria,1G1VY@1117|Cyanobacteria,1H7SC@1150|Oscillatoriales 1117|Cyanobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GDHHQS3_k127_5662785_0 105559.Nwat_1185 4.172e-176 566.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales 135613|Chromatiales L TIGRFAM ATP-dependent helicase HrpA - - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind GDHHQS3_k127_5668830_0 1384056.N787_00865 7.828e-188 597.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1X3DG@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the aldehyde dehydrogenase family betB GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_5668830_3 1121015.N789_01005 8.611e-91 305.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1X562@135614|Xanthomonadales 135614|Xanthomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 GDHHQS3_k127_5668830_2 114615.BRADO5212 2.635e-99 336.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase GDHHQS3_k127_5668830_1 390235.PputW619_2014 1.478e-159 510.0 COG3384@1|root,COG3384@2|Bacteria 2|Bacteria S 3-carboxyethylcatechol 2,3-dioxygenase activity hpaD - 1.13.11.15,1.13.11.74,1.13.11.76 ko:K00455,ko:K15058,ko:K15059 ko00350,ko00627,ko01120,ko01220,map00350,map00627,map01120,map01220 M00533 R03303,R05405 RC00387,RC00643 ko00000,ko00001,ko00002,ko01000 - - - LigB GDHHQS3_k127_5668830_4 1392838.AWNM01000019_gene4051 2.746e-08 56.0 COG3384@1|root,COG3384@2|Bacteria,1NRIH@1224|Proteobacteria,2W0P8@28216|Betaproteobacteria,3T5YW@506|Alcaligenaceae 28216|Betaproteobacteria C Catalytic LigB subunit of aromatic ring-opening dioxygenase amnA - - ko:K15058 ko00627,ko01120,map00627,map01120 - R05405 RC00387 ko00000,ko00001 - - - LigB GDHHQS3_k127_5679771_10 1416759.AYMR01000007_gene966 5.643e-60 215.0 2DBF0@1|root,2Z8VT@2|Bacteria,2I88D@201174|Actinobacteria 201174|Actinobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - 1.3.1.22 ko:K12343 ko00140,map00140 - R02208,R02497,R08954,R10242 RC00145 ko00000,ko00001,ko01000 - - - Steroid_dh GDHHQS3_k127_5679771_2 194439.CT1275 1.671e-125 414.0 COG1064@1|root,COG1064@2|Bacteria,1FERU@1090|Chlorobi 1090|Chlorobi C alcohol dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N GDHHQS3_k127_5679771_11 1415778.JQMM01000001_gene1934 6.981e-33 134.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1J66J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp GDHHQS3_k127_5679771_8 595494.Tola_2879 3.062e-80 272.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,1Y5P1@135624|Aeromonadales 135624|Aeromonadales S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 GDHHQS3_k127_5679771_0 1234364.AMSF01000095_gene2511 2.664e-264 827.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1X2YR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C GDHHQS3_k127_5679771_6 1269813.ATUL01000023_gene655 5.024e-87 297.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt GDHHQS3_k127_5679771_12 1278309.KB907100_gene1966 9.285e-13 72.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XM23@135619|Oceanospirillales 135619|Oceanospirillales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S GDHHQS3_k127_5679771_9 2340.JV46_14880 3.385e-73 265.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1J5PD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C GDHHQS3_k127_5679771_1 1049564.TevJSym_ap00800 5.115e-144 462.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1J4RX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 ACCA GDHHQS3_k127_5679771_5 582744.Msip34_1144 9.715e-89 302.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KM5R@206350|Nitrosomonadales 206350|Nitrosomonadales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c GDHHQS3_k127_5679771_7 472759.Nhal_0222 3.211e-84 304.0 COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg GDHHQS3_k127_5679771_4 572477.Alvin_1754 4.459e-89 297.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales 135613|Chromatiales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C GDHHQS3_k127_5679771_3 472759.Nhal_2414 1.107e-102 345.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales 135613|Chromatiales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 GDHHQS3_k127_5701921_2 1279009.ADICEAN_03948 7.494e-14 74.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47NKR@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.86 ko:K13745 ko00260,ko01120,map00260,map01120 - R07650 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC GDHHQS3_k127_5701921_0 582744.Msip34_1119 4.289e-57 203.0 29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,2VRJJ@28216|Betaproteobacteria,2KMRG@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_5701921_1 1123279.ATUS01000001_gene2606 1.363e-46 192.0 COG0304@1|root,COG0304@2|Bacteria,1R2NH@1224|Proteobacteria,1SEJN@1236|Gammaproteobacteria,1J6XZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ beta-ketoacyl-acyl-carrier-protein synthase II activity - - - - - - - - - - - - - GDHHQS3_k127_5701921_4 382464.ABSI01000010_gene3402 0.0003244 53.0 COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,2IUI0@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA GDHHQS3_k127_5701921_3 157783.LK03_16810 8.868e-08 62.0 COG2194@1|root,COG2194@2|Bacteria 2|Bacteria T sulfuric ester hydrolase activity - - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1499,DUF1705,Sulfatase GDHHQS3_k127_5706993_6 1132855.KB913035_gene1476 5.179e-26 117.0 COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,2VRF2@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - DUF4398,OmpA GDHHQS3_k127_5706993_7 472759.Nhal_2790 1.733e-08 61.0 2E41E@1|root,32YY1@2|Bacteria,1NGB3@1224|Proteobacteria,1SDTK@1236|Gammaproteobacteria,1X1PQ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4398) - - - - - - - - - - - - DUF4398 GDHHQS3_k127_5706993_2 1234364.AMSF01000010_gene596 9.545e-146 469.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1X4ZT@135614|Xanthomonadales 135614|Xanthomonadales Q 2-keto-4-pentenoate hydratase uptA - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase GDHHQS3_k127_5706993_0 1121033.AUCF01000016_gene5419 7.417e-192 603.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2TRFI@28211|Alphaproteobacteria,2JPCP@204441|Rhodospirillales 204441|Rhodospirillales Q homogentisate 1,2-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA GDHHQS3_k127_5706993_4 1279017.AQYJ01000029_gene3514 1.215e-34 138.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,467UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 GDHHQS3_k127_5706993_3 1094184.KWO_0110925 2.967e-42 165.0 COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1S5Z3@1236|Gammaproteobacteria,1X659@135614|Xanthomonadales 135614|Xanthomonadales S PAP2 superfamily - - - - - - - - - - - - PAP2 GDHHQS3_k127_5706993_1 1121374.KB891586_gene2811 4.114e-175 572.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily mdoB - - - - - - - - - - - Sulfatase GDHHQS3_k127_5706993_5 1120972.AUMH01000007_gene1617 1.65e-29 118.0 2CA5R@1|root,2Z81H@2|Bacteria,1UYYB@1239|Firmicutes,4HA7J@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4153) - - - - - - - - - - - - DUF4153 GDHHQS3_k127_5716190_2 1267535.KB906767_gene705 1.803e-108 364.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_31 GDHHQS3_k127_5716190_4 1121930.AQXG01000001_gene953 1.335e-11 64.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_5716190_5 153948.NAL212_2555 2.929e-09 60.0 2DRB5@1|root,33B20@2|Bacteria,1PVK8@1224|Proteobacteria,2VYTH@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox GDHHQS3_k127_5716190_1 247639.MGP2080_08319 1.311e-117 387.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N GDHHQS3_k127_5716190_0 247639.MGP2080_08314 4.172e-178 576.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1JA3P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 GDHHQS3_k127_5716190_3 1267005.KB911264_gene3157 2.528e-21 94.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria 28211|Alphaproteobacteria E oxidoreductase - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO GDHHQS3_k127_5723111_2 1385517.N800_02520 5.771e-58 211.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales 135614|Xanthomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh GDHHQS3_k127_5723111_1 1121015.N789_00825 7.343e-60 214.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1X3N1@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C GDHHQS3_k127_5723111_0 1163407.UU7_12319 4.326e-69 237.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase GDHHQS3_k127_5735236_12 84531.JMTZ01000008_gene3392 5.175e-09 60.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1X5YQ@135614|Xanthomonadales 135614|Xanthomonadales M Peptidyl-prolyl cis-trans VL23_22180 - 5.2.1.8 ko:K01802,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N GDHHQS3_k127_5735236_9 28229.ND2E_2629 9.183e-59 211.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,2Q685@267889|Colwelliaceae 1236|Gammaproteobacteria KT PspA/IM30 family pspA GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - ko:K03969 - - - - ko00000 - - - PspA_IM30 GDHHQS3_k127_5735236_11 1121033.AUCF01000003_gene3238 1.22e-22 100.0 2CJWQ@1|root,32C05@2|Bacteria,1Q6G6@1224|Proteobacteria,2VCM2@28211|Alphaproteobacteria,2JUC8@204441|Rhodospirillales 204441|Rhodospirillales S Phage shock protein B - - - ko:K03970 - - - - ko00000,ko02048 - - - PspB GDHHQS3_k127_5735236_10 1380394.JADL01000001_gene2267 1.402e-27 119.0 COG1983@1|root,COG1983@2|Bacteria,1NECC@1224|Proteobacteria,2UEYZ@28211|Alphaproteobacteria,2JTP5@204441|Rhodospirillales 204441|Rhodospirillales KT PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC GDHHQS3_k127_5735236_7 1163407.UU7_05389 3.343e-69 246.0 COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 GDHHQS3_k127_5735236_0 1123368.AUIS01000027_gene1353 2.947e-168 543.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,2NC4X@225057|Acidithiobacillales 225057|Acidithiobacillales M Belongs to the mannose-6-phosphate isomerase type 2 family - - 2.7.7.13,5.3.1.8 ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase GDHHQS3_k127_5735236_6 1122185.N792_13200 6.107e-70 248.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,1X3YC@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind GDHHQS3_k127_5735236_4 1442599.JAAN01000035_gene697 7.222e-72 247.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1X327@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rmlC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom GDHHQS3_k127_5735236_2 1123377.AUIV01000013_gene2294 3.54e-137 441.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1X399@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rmlA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase GDHHQS3_k127_5735236_1 1385517.N800_00405 1.563e-159 509.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1X3KP@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rmlB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd GDHHQS3_k127_5735236_8 203122.Sde_0996 2.648e-60 212.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,466WC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB GDHHQS3_k127_5735236_5 506534.Rhein_0102 7.62e-72 257.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GDHHQS3_k127_5735236_3 870187.Thini_1999 2.768e-105 351.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales 72273|Thiotrichales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt GDHHQS3_k127_5735448_0 1117647.M5M_11425 8.255e-132 423.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J4MS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases aldH - 1.2.1.54,1.2.1.99 ko:K09472,ko:K12254 ko00330,ko01100,map00330,map01100 M00136 R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5278 Aldedh GDHHQS3_k127_5735448_1 1134474.O59_001218 3.942e-125 415.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1FFYY@10|Cellvibrio 1236|Gammaproteobacteria V MatE - - - - - - - - - - - - MatE GDHHQS3_k127_5735448_4 338969.Rfer_3267 2.402e-64 227.0 COG0625@1|root,COG0625@2|Bacteria,1PPF9@1224|Proteobacteria,2VQQZ@28216|Betaproteobacteria 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_3,GST_N GDHHQS3_k127_5735448_7 1110697.NCAST_23_01440 2.481e-10 61.0 COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4G2AF@85025|Nocardiaceae 201174|Actinobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_5735448_6 366602.Caul_2323 7.144e-29 116.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,2UFMJ@28211|Alphaproteobacteria,2KJH2@204458|Caulobacterales 204458|Caulobacterales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - GDHHQS3_k127_5735448_5 1279015.KB908460_gene2923 2.065e-37 143.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria IV02_17390 - - ko:K09948 - - - - ko00000 - - - DUF1244 GDHHQS3_k127_5735448_2 1121374.KB891575_gene815 4.464e-109 360.0 COG1082@1|root,COG1082@2|Bacteria,1R4JM@1224|Proteobacteria,1S5N0@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 GDHHQS3_k127_5735448_3 247639.MGP2080_12053 5.511e-109 362.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase GDHHQS3_k127_5744241_1 187272.Mlg_2878 3.188e-104 345.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GDHHQS3_k127_5744241_3 314278.NB231_10873 2.658e-93 317.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales 135613|Chromatiales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc GDHHQS3_k127_5744241_7 1452718.JBOY01000005_gene3322 0.0009762 49.0 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria C atp synthase atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I GDHHQS3_k127_5744241_0 314287.GB2207_08731 5.708e-114 377.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A GDHHQS3_k127_5744241_6 1318628.MARLIPOL_10356 4.145e-33 130.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,468H6@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C GDHHQS3_k127_5744241_4 1300345.LF41_1508 4.907e-40 153.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1X60B@135614|Xanthomonadales 135614|Xanthomonadales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B GDHHQS3_k127_5744241_5 1300345.LF41_1509 4.955e-35 140.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1X6DJ@135614|Xanthomonadales 135614|Xanthomonadales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP GDHHQS3_k127_5744241_2 1500890.JQNL01000001_gene1703 2.023e-99 328.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1X31U@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N GDHHQS3_k127_5751244_1 566466.NOR53_1852 2.849e-177 556.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1J9DQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold fldW - 4.1.1.45,4.2.1.83 ko:K03392,ko:K10220 ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120 M00038 R04323,R04478 RC00498,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 GDHHQS3_k127_5751244_3 1168065.DOK_12306 3.135e-155 495.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,1RQ8V@1236|Gammaproteobacteria,1J5VK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold - - 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R04277 RC03110 ko00000,ko00001,ko01000 - - - Amidohydro_2 GDHHQS3_k127_5751244_10 1168065.DOK_12311 1.071e-59 210.0 COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria,1JAUT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Aromatic-ring-opening dioxygenase LigAB, LigA subunit ligA_1 - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA GDHHQS3_k127_5751244_4 1123399.AQVE01000005_gene959 1.213e-150 480.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols mhpB - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB GDHHQS3_k127_5751244_2 1168065.DOK_12321 1.817e-165 525.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1J9Q9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S dehydrogenases and related proteins - - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C GDHHQS3_k127_5751244_0 1335760.ASTG01000003_gene1502 4.955e-187 590.0 COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria,2K1NN@204457|Sphingomonadales 204457|Sphingomonadales CH Catalyzes the formation of protocatechuate from 4-hydroxybenzoate - - 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 GDHHQS3_k127_5751244_8 1244869.H261_01182 9.847e-68 237.0 COG1309@1|root,COG1309@2|Bacteria,1PF4T@1224|Proteobacteria,2UN0E@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GDHHQS3_k127_5751244_9 76114.ebA720 3.325e-67 239.0 COG1024@1|root,COG1024@2|Bacteria,1REB8@1224|Proteobacteria,2W1XT@28216|Betaproteobacteria,2KYP7@206389|Rhodocyclales 206389|Rhodocyclales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 GDHHQS3_k127_5751244_5 670292.JH26_12415 3.717e-149 482.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,1JX8D@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, middle domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_5751244_6 76114.ebA722 6.251e-136 436.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,2KYCR@206389|Rhodocyclales 206389|Rhodocyclales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 GDHHQS3_k127_5751244_7 76114.ebA723 3.28e-99 329.0 COG1028@1|root,COG1028@2|Bacteria,1RCD5@1224|Proteobacteria,2W04R@28216|Betaproteobacteria,2KXRA@206389|Rhodocyclales 206389|Rhodocyclales IQ KR domain - - - ko:K07535 ko00362,ko01120,ko01220,map00362,map01120,map01220 M00540 R05582 RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 GDHHQS3_k127_5751244_11 1244869.H261_03563 1.717e-44 164.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,2JRE7@204441|Rhodospirillales 204441|Rhodospirillales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - 6.2.1.32 ko:K08295 ko00627,ko01120,map00627,map01120 - R00982 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C GDHHQS3_k127_5761375_3 1205680.CAKO01000002_gene2535 2.803e-64 221.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JR19@204441|Rhodospirillales 204441|Rhodospirillales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C GDHHQS3_k127_5761375_0 977880.RALTA_A1577 0.0 1050.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,1JZS1@119060|Burkholderiaceae 28216|Betaproteobacteria G PQQ-dependent dehydrogenase, methanol ethanol family exaA1 - 1.1.2.9,1.1.9.1 ko:K17760,ko:K20936 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ GDHHQS3_k127_5761375_5 765913.ThidrDRAFT_2994 2.431e-15 76.0 2CJ4Q@1|root,32S97@2|Bacteria,1N0B9@1224|Proteobacteria,1S97T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ethyl tert-butyl ether degradation ethD - - - - - - - - - - - EthD GDHHQS3_k127_5761375_1 754476.Q7A_3069 6.13e-107 356.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,460F1@72273|Thiotrichales 72273|Thiotrichales S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ - 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ GDHHQS3_k127_5761375_4 526225.Gobs_2887 4.844e-16 79.0 COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria,4EW6Q@85013|Frankiales 201174|Actinobacteria E Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR GDHHQS3_k127_5781069_4 998674.ATTE01000001_gene511 9.836e-53 190.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4601Y@72273|Thiotrichales 72273|Thiotrichales F Belongs to the GARS family purD - 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N,SAICAR_synt GDHHQS3_k127_5781069_0 1211114.ALIP01000116_gene2648 5.499e-201 638.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS GDHHQS3_k127_5781069_6 493475.GARC_2269 1.099e-15 81.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,468HA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 GDHHQS3_k127_5781069_5 391615.ABSJ01000001_gene427 1.391e-18 95.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mj0042 family finger-like - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 GDHHQS3_k127_5781069_8 519989.ECTPHS_08728 9.001e-08 62.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S7FF@1236|Gammaproteobacteria,1WYCM@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 GDHHQS3_k127_5781069_3 1286106.MPL1_06567 5.932e-76 264.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,460FX@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran GDHHQS3_k127_5781069_2 998674.ATTE01000001_gene2317 6.749e-116 378.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,4606Q@72273|Thiotrichales 72273|Thiotrichales L Exodeoxyribonuclease III xth xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos GDHHQS3_k127_5781069_1 1279017.AQYJ01000023_gene3254 3.858e-159 512.0 COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,1T226@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Permeases of the major facilitator superfamily Z012_03780 - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 GDHHQS3_k127_5781069_7 1233950.IW22_23720 6.969e-11 72.0 2EIYT@1|root,33CQ0@2|Bacteria,4P77Y@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - GDHHQS3_k127_5787780_1 1128421.JAGA01000002_gene1742 1.076e-134 442.0 COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria 2|Bacteria O Protein of unknown function, DUF255 yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH GDHHQS3_k127_5787780_0 1122137.AQXF01000007_gene3562 7.66e-322 1004.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase GDHHQS3_k127_5787780_2 1173026.Glo7428_2279 1.508e-71 248.0 COG0212@1|root,COG0212@2|Bacteria,1G2B2@1117|Cyanobacteria 1117|Cyanobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - - - - - - - - - - - GDHHQS3_k127_5788503_1 1205753.A989_11374 1.083e-112 368.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1X31P@135614|Xanthomonadales 135614|Xanthomonadales J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e GDHHQS3_k127_5788503_5 754476.Q7A_1243 5.043e-44 165.0 COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria,462TR@72273|Thiotrichales 72273|Thiotrichales OU of membrane protease - - - ko:K07340 - - - - ko00000 - - - NfeD GDHHQS3_k127_5788503_0 546414.Deide_07280 8.426e-124 405.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion qmcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Band_7,Band_7_C GDHHQS3_k127_5788503_3 104623.Ser39006_02423 1.525e-74 258.0 COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 GDHHQS3_k127_5788503_2 243233.MCA2790 8.069e-93 319.0 COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1XH17@135618|Methylococcales 135618|Methylococcales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 GDHHQS3_k127_5788503_4 870187.Thini_3578 9.535e-46 170.0 COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,1SFB1@1236|Gammaproteobacteria,462H1@72273|Thiotrichales 72273|Thiotrichales S SEC-C Motif Domain Protein - - - - - - - - - - - - - GDHHQS3_k127_5844308_0 1211114.ALIP01000007_gene2608 5.977e-125 413.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1X3YE@135614|Xanthomonadales 135614|Xanthomonadales D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge GDHHQS3_k127_5844308_2 1123073.KB899242_gene930 3.919e-40 159.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1X3YH@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C GDHHQS3_k127_5844308_1 1385517.N800_01285 7.22e-98 328.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1X2ZU@135614|Xanthomonadales 135614|Xanthomonadales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 GDHHQS3_k127_5848231_2 1122604.JONR01000011_gene3598 3.802e-25 106.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,1X8EZ@135614|Xanthomonadales 135614|Xanthomonadales K Helix-turn-helix XRE-family like proteins - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_5848231_1 1266908.AQPB01000059_gene2670 2.014e-53 193.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria,1WXG0@135613|Chromatiales 135613|Chromatiales V Type II restriction enzyme, methylase - - - - - - - - - - - - - GDHHQS3_k127_5848231_0 1266908.AQPB01000059_gene2670 1.26e-82 282.0 COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria,1WXG0@135613|Chromatiales 135613|Chromatiales V Type II restriction enzyme, methylase - - - - - - - - - - - - - GDHHQS3_k127_5848231_3 85643.Tmz1t_2741 8.141e-16 87.0 COG1002@1|root,COG1002@2|Bacteria 2|Bacteria V DNA modification - - - - - - - - - - - - - GDHHQS3_k127_5903107_0 1123368.AUIS01000009_gene2455 2.596e-298 955.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,2NC0P@225057|Acidithiobacillales 225057|Acidithiobacillales E Domain of unknown function (DUF3458_C) ARM repeats pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 GDHHQS3_k127_5903107_2 1163408.UU9_08907 2.622e-76 282.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,1X2XV@135614|Xanthomonadales 135614|Xanthomonadales E dehydratase ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP GDHHQS3_k127_5903107_3 631362.Thi970DRAFT_00635 1.758e-71 246.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1X0M6@135613|Chromatiales 135613|Chromatiales L Methyladenine glycosylase - - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco GDHHQS3_k127_5903107_1 1121405.dsmv_1943 6.471e-134 437.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,42UCU@68525|delta/epsilon subdivisions,2WR0U@28221|Deltaproteobacteria,2MKMP@213118|Desulfobacterales 28221|Deltaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC GDHHQS3_k127_5903107_4 472759.Nhal_0931 2.122e-55 199.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1WXZ5@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 GDHHQS3_k127_5903107_5 1242864.D187_007270 1.004e-28 126.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria 1224|Proteobacteria T FHA domain - - - - - - - - - - - - FHA,Yop-YscD_cpl GDHHQS3_k127_5916573_1 1121374.KB891575_gene803 9.145e-144 483.0 COG4773@1|root,COG4773@2|Bacteria,1NRKQ@1224|Proteobacteria,1SJXP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_5916573_2 1121374.KB891575_gene801 3.427e-87 297.0 2CEWZ@1|root,33QME@2|Bacteria,1NTHN@1224|Proteobacteria,1SKH8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_5916573_0 1121374.KB891575_gene800 4.883e-155 498.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 GDHHQS3_k127_5918642_2 1255043.TVNIR_1057 1.907e-16 83.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZF3@135613|Chromatiales 135613|Chromatiales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA GDHHQS3_k127_5918642_3 913325.N799_06565 5.207e-10 62.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,1X83G@135614|Xanthomonadales 135614|Xanthomonadales S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - ZapB GDHHQS3_k127_5918642_1 187272.Mlg_2541 1.68e-21 102.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1WYR7@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 GDHHQS3_k127_5918642_0 1123073.KB899241_gene2767 5.356e-163 524.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1X34E@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 GDHHQS3_k127_5920917_0 1198452.Jab_1c09800 1.169e-138 462.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VI6S@28216|Betaproteobacteria,476XN@75682|Oxalobacteraceae 28216|Betaproteobacteria E ERAP1-like C-terminal domain - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 GDHHQS3_k127_5920917_5 450851.PHZ_c0288 0.0005298 45.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KI2D@204458|Caulobacterales 204458|Caulobacterales E PFAM peptidase M19 renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 GDHHQS3_k127_5920917_1 1122137.AQXF01000004_gene1809 2.335e-81 288.0 COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria 1224|Proteobacteria P Mn2 and Fe2 transporters of the NRAMP family Z012_09610 - - - - - - - - - - - Nramp GDHHQS3_k127_5920917_2 1120956.JHZK01000002_gene1027 2.775e-40 162.0 COG2175@1|root,COG2175@2|Bacteria,1Q8GZ@1224|Proteobacteria,2VCP6@28211|Alphaproteobacteria,1JQ4Y@119043|Rhodobiaceae 28211|Alphaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD GDHHQS3_k127_5920917_3 627192.SLG_31140 1.213e-22 102.0 COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,2U0PN@28211|Alphaproteobacteria,2KD49@204457|Sphingomonadales 204457|Sphingomonadales E Amino acid permease - - - ko:K11735 - - - - ko00000,ko02000 2.A.3.1.4,2.A.3.1.5 - - AA_permease GDHHQS3_k127_5923641_4 1387197.AWGA01000006_gene1439 4.851e-05 46.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N GDHHQS3_k127_5923641_0 745411.B3C1_16004 1.879e-175 568.0 COG4805@1|root,COG4805@2|Bacteria,1PIM6@1224|Proteobacteria,1RRW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 GDHHQS3_k127_5923641_3 1005395.CSV86_01293 5.55e-25 109.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,1YYRD@136845|Pseudomonas putida group 1236|Gammaproteobacteria S PFAM DoxX family protein - - - ko:K15977 - - - - ko00000 - - - DoxX GDHHQS3_k127_5923641_2 882.DVU_1702 9.954e-41 159.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42M5N@68525|delta/epsilon subdivisions,2X5TD@28221|Deltaproteobacteria,2MBXV@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 GDHHQS3_k127_5923641_1 1123073.KB899245_gene133 4.011e-63 227.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X50D@135614|Xanthomonadales 135614|Xanthomonadales S adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans GDHHQS3_k127_5926591_0 1385515.N791_13170 1.527e-192 604.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN GDHHQS3_k127_5926591_3 713587.THITH_01775 4.765e-84 290.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria 1236|Gammaproteobacteria F COG0209 Ribonucleotide reductase, alpha subunit nrdJb - - - - - - - - - - - - GDHHQS3_k127_5926591_6 765911.Thivi_0168 2.286e-31 135.0 COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,1RQ64@1236|Gammaproteobacteria,1WXVE@135613|Chromatiales 135613|Chromatiales L NERD domain protein - - - - - - - - - - - - NERD,zf-C4_Topoisom GDHHQS3_k127_5926591_2 1382359.JIAL01000001_gene644 1.45e-112 382.0 COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia 204432|Acidobacteriia E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GDHHQS3_k127_5926591_1 465817.ETA_06670 4.987e-150 486.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3X5JH@551|Erwinia 1236|Gammaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 Glycos_trans_3N,Glycos_transf_3,PYNP_C GDHHQS3_k127_5926591_5 1121459.AQXE01000007_gene679 1.198e-35 140.0 COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2MDR0@213115|Desulfovibrionales 28221|Deltaproteobacteria F PFAM CMP dCMP deaminase zinc-binding cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 GDHHQS3_k127_5926591_4 32057.KB217480_gene8180 8.762e-45 167.0 COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1HK8V@1161|Nostocales 1117|Cyanobacteria J TIGRFAM endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP GDHHQS3_k127_5926591_7 755732.Fluta_0261 3.352e-12 66.0 2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - 1.3.1.22 ko:K12343 ko00140,map00140 - R02208,R02497,R08954,R10242 RC00145 ko00000,ko00001,ko01000 - - - Steroid_dh GDHHQS3_k127_5948409_2 1380394.JADL01000010_gene4323 7.099e-152 492.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2JQGJ@204441|Rhodospirillales 204441|Rhodospirillales C Domain of unknown function (DUF4445) - - - - - - - - - - - - DUF4445,Fer2 GDHHQS3_k127_5948409_3 745014.OMB55_00017560 3.496e-137 445.0 COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RZF4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG1410 Methionine synthase I cobalamin-binding domain - - - - - - - - - - - - Pterin_bind GDHHQS3_k127_5948409_10 1380380.JIAX01000008_gene1846 1.501e-15 81.0 2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Virulence factor - - - - - - - - - - - - Virulence_fact GDHHQS3_k127_5948409_7 247639.MGP2080_08811 1.835e-63 224.0 28I8Y@1|root,2Z8BR@2|Bacteria,1MXN1@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1638) - - - - - - - - - - - - DUF1638 GDHHQS3_k127_5948409_5 998674.ATTE01000001_gene278 3.736e-109 357.0 COG5012@1|root,COG5012@2|Bacteria,1QDZ3@1224|Proteobacteria,1RYST@1236|Gammaproteobacteria 1236|Gammaproteobacteria S B12 binding domain - - - - - - - - - - - - B12-binding,B12-binding_2 GDHHQS3_k127_5948409_4 246200.SPO0143 1.462e-114 379.0 COG1600@1|root,COG1600@2|Bacteria,1NG2H@1224|Proteobacteria,2UMVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4 GDHHQS3_k127_5948409_1 1121937.AUHJ01000007_gene1776 1.512e-158 528.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,46D93@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_5948409_9 1380394.JADL01000001_gene2033 9.406e-31 142.0 COG2905@1|root,COG2905@2|Bacteria,1R2AR@1224|Proteobacteria,2TZF3@28211|Alphaproteobacteria,2JZ0Y@204441|Rhodospirillales 204441|Rhodospirillales T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding GDHHQS3_k127_5948409_0 1121033.AUCF01000003_gene3320 1.415e-230 750.0 COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,2TRSY@28211|Alphaproteobacteria,2JPPS@204441|Rhodospirillales 204441|Rhodospirillales V ABC transporter transmembrane region - - - ko:K02021 - - - - ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran,cNMP_binding GDHHQS3_k127_5948409_8 314607.KB13_305 3.916e-46 183.0 29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_5948409_6 402881.Plav_1936 7.682e-74 259.0 COG2035@1|root,COG2035@2|Bacteria 2|Bacteria S Membrane - - - ko:K08974 - - - - ko00000 - - - DUF368 GDHHQS3_k127_5953370_4 396588.Tgr7_0998 6.652e-226 708.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales 135613|Chromatiales C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M GDHHQS3_k127_5953370_0 713586.KB900536_gene3054 2.112e-263 826.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N GDHHQS3_k127_5953370_19 1384054.N790_03870 1.994e-43 160.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1X6XC@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 GDHHQS3_k127_5953370_16 472759.Nhal_3691 1.863e-64 227.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S4ZA@1236|Gammaproteobacteria,1X25S@135613|Chromatiales 135613|Chromatiales C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 GDHHQS3_k127_5953370_14 935567.JAES01000001_gene2309 1.188e-79 269.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,1X2Z3@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 GDHHQS3_k127_5953370_6 1469245.JFBG01000086_gene1621 4.798e-147 474.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh GDHHQS3_k127_5953370_2 187272.Mlg_1964 2.02e-234 751.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 GDHHQS3_k127_5953370_3 1384054.N790_03845 2.087e-230 719.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1X2ZD@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB GDHHQS3_k127_5953370_15 1122185.N792_06600 1.757e-69 239.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1X3TC@135614|Xanthomonadales 135614|Xanthomonadales C NADH dehydrogenase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx GDHHQS3_k127_5953370_1 666685.R2APBS1_1462 3.958e-237 737.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1X3JR@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa GDHHQS3_k127_5953370_11 1384054.N790_03830 6.419e-92 308.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1X302@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa GDHHQS3_k127_5953370_9 1121013.P873_09390 7.306e-101 330.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1X4BY@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 GDHHQS3_k127_5953370_18 1469245.JFBG01000086_gene1628 7.062e-48 174.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,1WYJ8@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 GDHHQS3_k127_5953370_21 380358.XALC_0997 1.095e-17 90.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1X70B@135614|Xanthomonadales 135614|Xanthomonadales U Preprotein translocase subunit SecG secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG GDHHQS3_k127_5953370_12 1123401.JHYQ01000005_gene292 5.854e-88 299.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,4608G@72273|Thiotrichales 72273|Thiotrichales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM GDHHQS3_k127_5953370_13 1500890.JQNL01000001_gene2598 3.9e-80 276.0 COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,1RQTP@1236|Gammaproteobacteria,1X42F@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short GDHHQS3_k127_5953370_17 748247.AZKH_3313 1.512e-55 203.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,2VQVV@28216|Betaproteobacteria,2KVMI@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - GDHHQS3_k127_5953370_7 187272.Mlg_0413 1.15e-143 470.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1WWPA@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD GDHHQS3_k127_5953370_20 1385515.N791_04110 1.472e-31 130.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1X636@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0307 family - - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 GDHHQS3_k127_5953370_5 314278.NB231_05811 3.625e-211 665.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD GDHHQS3_k127_5953370_8 1384056.N787_10085 1.161e-143 501.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 GDHHQS3_k127_5953370_10 1234364.AMSF01000027_gene3497 3.376e-95 315.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1X2ZH@135614|Xanthomonadales 135614|Xanthomonadales J Involved in the processing of the 5'end of 16S rRNA rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 GDHHQS3_k127_5955719_1 247639.MGP2080_13869 4.719e-122 406.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria 1236|Gammaproteobacteria E amino acid frlA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - ko:K03294,ko:K19540 - - - - ko00000,ko02000 2.A.3.2,2.A.3.8.17 - iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365 AA_permease_2 GDHHQS3_k127_5955719_3 314285.KT71_05862 2.172e-91 308.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function Z012_09445 - - - - - - - - - - - Peptidase_M48 GDHHQS3_k127_5955719_5 517418.Ctha_0553 4.93e-25 111.0 COG0239@1|root,COG0239@2|Bacteria,1FE6H@1090|Chlorobi 1090|Chlorobi D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GDHHQS3_k127_5955719_4 1191523.MROS_2390 1.504e-32 129.0 COG1993@1|root,COG1993@2|Bacteria 2|Bacteria T acr, cog1993 - - - ko:K06199,ko:K09137 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CBS,DUF190 GDHHQS3_k127_5955719_6 1068980.ARVW01000001_gene3715 3.402e-19 98.0 COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,4E0FR@85010|Pseudonocardiales 201174|Actinobacteria EG metabolite transporter - - - ko:K15268 - - - - ko00000,ko02000 2.A.7.3.2 - - EamA GDHHQS3_k127_5955719_0 1316936.K678_05006 1.234e-202 642.0 COG5310@1|root,COG5310@2|Bacteria,1MUZB@1224|Proteobacteria,2TRTR@28211|Alphaproteobacteria,2JR46@204441|Rhodospirillales 204441|Rhodospirillales Q Homospermidine synthase hss - 2.5.1.44 ko:K00808 ko00960,ko01110,map00960,map01110 - R00018 RC00053 ko00000,ko00001,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP GDHHQS3_k127_5955719_2 1144275.COCOR_00931 4.594e-105 350.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42Z9B@68525|delta/epsilon subdivisions,2WMPJ@28221|Deltaproteobacteria,2YTYW@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C GDHHQS3_k127_5983115_1 485918.Cpin_3446 1.008e-84 282.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IV6M@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.1.53,3.5.1.6 ko:K01431,ko:K12251 ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100 M00046 R00905,R01152,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase GDHHQS3_k127_5983115_0 391625.PPSIR1_12543 1.091e-140 456.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales 28221|Deltaproteobacteria FH Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur GDHHQS3_k127_5989397_2 863365.XHC_3466 3.25e-13 70.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1X3C9@135614|Xanthomonadales 135614|Xanthomonadales H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_5989397_0 1242864.D187_010215 9.702e-114 381.0 COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYJ0@29|Myxococcales 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short GDHHQS3_k127_5989397_1 713586.KB900536_gene2495 1.574e-88 310.0 COG1368@1|root,COG1368@2|Bacteria 2|Bacteria M sulfuric ester hydrolase activity - - - - - - - - - - - - Sulfatase GDHHQS3_k127_5994208_2 247634.GPB2148_1848 1.154e-09 62.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C GDHHQS3_k127_5994208_1 1297569.MESS2_1480041 3.623e-156 509.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,43GY1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 GDHHQS3_k127_5994208_0 247634.GPB2148_1633 9.507e-212 666.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 GDHHQS3_k127_600305_1 314285.KT71_02627 1.466e-21 105.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_600305_0 1265503.KB905166_gene652 1.117e-96 342.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_6014927_1 666685.R2APBS1_1434 2.388e-165 543.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1X32S@135614|Xanthomonadales 135614|Xanthomonadales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 GDHHQS3_k127_6014927_2 1384056.N787_08025 1.25e-80 273.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales 135614|Xanthomonadales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 GDHHQS3_k127_6014927_3 1232683.ADIMK_0380 4.608e-18 87.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,4693D@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 GDHHQS3_k127_6014927_0 1415779.JOMH01000001_gene562 4.755e-176 578.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,1X3GP@135614|Xanthomonadales 135614|Xanthomonadales C acetyl-coa hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C GDHHQS3_k127_6014927_4 743721.Psesu_1688 2.09e-15 78.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1X41G@135614|Xanthomonadales 135614|Xanthomonadales L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T GDHHQS3_k127_6019874_5 1502770.JQMG01000001_gene1085 1.506e-24 105.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KNV2@206350|Nitrosomonadales 206350|Nitrosomonadales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - HlyD_D23 GDHHQS3_k127_6019874_2 1502770.JQMG01000001_gene1086 2.203e-155 502.0 COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria 28216|Betaproteobacteria MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP GDHHQS3_k127_6019874_0 76114.ebA2180 0.0 1095.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KVKK@206389|Rhodocyclales 206389|Rhodocyclales P P-type ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS GDHHQS3_k127_6019874_1 247634.GPB2148_2129 2.586e-182 582.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1J4US@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh GDHHQS3_k127_6019874_3 1121940.AUDZ01000007_gene2334 1.773e-152 495.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales 135619|Oceanospirillales C FAD linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 GDHHQS3_k127_6019874_4 1265313.HRUBRA_00325 1.322e-119 398.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,1RRJR@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Belongs to the TPP enzyme family mdlC - 4.1.1.7 ko:K01576 ko00627,ko01120,map00627,map01120 - R01764,R02672 RC00595 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_6022359_2 926569.ANT_06250 3.802e-57 207.0 COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi 200795|Chloroflexi L Domain of unknown function DUF83 - - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - Cas_Cas4 GDHHQS3_k127_6022359_1 926569.ANT_00510 1.761e-91 309.0 COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi 200795|Chloroflexi F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase GDHHQS3_k127_6022359_3 926569.ANT_00520 8.492e-33 135.0 COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi 200795|Chloroflexi NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - zf-B_box GDHHQS3_k127_6022359_0 926569.ANT_00530 2.122e-211 671.0 COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi 200795|Chloroflexi L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N GDHHQS3_k127_6024599_2 1163408.UU9_16863 1.808e-10 66.0 COG3308@1|root,COG3308@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - DUF2069 GDHHQS3_k127_6024599_0 1123256.KB907942_gene91 1.282e-77 270.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1X4PZ@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red GDHHQS3_k127_6024599_1 1384056.N787_07800 7.872e-66 237.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1X3UE@135614|Xanthomonadales 135614|Xanthomonadales S UPF0761 membrane protein rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB GDHHQS3_k127_6026317_4 1125863.JAFN01000001_gene3165 1.591e-65 229.0 COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,42PVV@68525|delta/epsilon subdivisions,2WIN9@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - - - - - - - - - - Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIV GDHHQS3_k127_6026317_0 1121918.ARWE01000001_gene171 1.845e-172 552.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PP9@68525|delta/epsilon subdivisions,2WMFX@28221|Deltaproteobacteria,43T5W@69541|Desulfuromonadales 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM GDHHQS3_k127_6026317_5 1125863.JAFN01000001_gene3167 2.714e-55 195.0 2BBG1@1|root,324ZB@2|Bacteria,1RHTK@1224|Proteobacteria,42URH@68525|delta/epsilon subdivisions,2WQKH@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Quinohemoprotein amine dehydrogenase, gamma subunit - - - - - - - - - - - - QH-AmDH_gamma GDHHQS3_k127_6026317_1 1125863.JAFN01000001_gene3168 7.09e-132 429.0 COG3391@1|root,COG3391@2|Bacteria,1P6I0@1224|Proteobacteria,42Q47@68525|delta/epsilon subdivisions,2WJYF@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - - GDHHQS3_k127_6026317_3 1121918.ARWE01000001_gene174 2.453e-72 252.0 COG0826@1|root,COG0826@2|Bacteria,1RGGH@1224|Proteobacteria,42RX8@68525|delta/epsilon subdivisions,2WNAI@28221|Deltaproteobacteria,43THH@69541|Desulfuromonadales 28221|Deltaproteobacteria O peptidase U32 - - - - - - - - - - - - - GDHHQS3_k127_6026317_2 1232410.KI421415_gene3048 3.92e-121 396.0 COG0826@1|root,COG0826@2|Bacteria,1R58U@1224|Proteobacteria,42Q3K@68525|delta/epsilon subdivisions,2WMIH@28221|Deltaproteobacteria,43T39@69541|Desulfuromonadales 28221|Deltaproteobacteria O Peptidase family U32 - - - - - - - - - - - - Peptidase_U32 GDHHQS3_k127_6026317_6 1121918.ARWE01000001_gene176 4.287e-42 158.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria 1224|Proteobacteria V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain - - - ko:K06147,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 GDHHQS3_k127_6029348_2 247634.GPB2148_3140 7.21e-76 268.0 COG3386@1|root,COG3386@2|Bacteria,1RFKJ@1224|Proteobacteria,1S4X1@1236|Gammaproteobacteria,1J68P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - SGL GDHHQS3_k127_6029348_4 1121324.CLIT_2c03230 1.052e-30 132.0 COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia 186801|Clostridia H Copper amine oxidase N-terminal domain - - - - - - - - - - - - Cu_amine_oxidN1 GDHHQS3_k127_6029348_3 748658.KB907312_gene1807 2.257e-51 190.0 COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales 135613|Chromatiales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 GDHHQS3_k127_6029348_0 1183438.GKIL_1522 1.634e-157 512.0 COG0531@1|root,COG0531@2|Bacteria,1G2VF@1117|Cyanobacteria 1117|Cyanobacteria E PFAM Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GDHHQS3_k127_6029348_1 627192.SLG_31140 1.049e-132 434.0 COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,2U0PN@28211|Alphaproteobacteria,2KD49@204457|Sphingomonadales 204457|Sphingomonadales E Amino acid permease - - - ko:K11735 - - - - ko00000,ko02000 2.A.3.1.4,2.A.3.1.5 - - AA_permease GDHHQS3_k127_6040356_2 313606.M23134_01148 8.438e-54 201.0 2F4SK@1|root,33XF9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6040356_4 449447.MAE_38920 6.825e-32 126.0 COG3549@1|root,COG3549@2|Bacteria,1GB1B@1117|Cyanobacteria 1117|Cyanobacteria S Plasmid maintenance system killer - - - ko:K07334 - - - - ko00000,ko02048 - - - HigB-like_toxin GDHHQS3_k127_6040356_5 287.DR97_2010 8.126e-12 69.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,1YGUW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins vapI - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_6040356_7 1120999.JONM01000009_gene290 0.0003718 44.0 COG3093@1|root,COG3093@2|Bacteria 2|Bacteria K addiction module antidote protein HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3,HTH_31 GDHHQS3_k127_6040356_1 1121004.ATVC01000018_gene1932 1.357e-196 628.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,2KQEU@206351|Neisseriales 206351|Neisseriales T Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK GDHHQS3_k127_6040356_0 566466.NOR53_824 0.0 1235.0 COG4447@1|root,COG4447@2|Bacteria,1R6KJ@1224|Proteobacteria 1224|Proteobacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 GDHHQS3_k127_6040356_3 551789.ATVJ01000001_gene2146 1.331e-44 165.0 COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - 2.7.10.2,3.3.2.9 ko:K01253,ko:K08253 ko00980,ko04976,ko05204,map00980,map04976,map05204 - R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443 RC01447,RC01728,RC01764,RC02528 ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GDHHQS3_k127_6074528_2 1469245.JFBG01000054_gene2109 6.926e-12 68.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1WYST@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 GDHHQS3_k127_6074528_1 857087.Metme_0076 4.438e-45 169.0 COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1SC8R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA GDHHQS3_k127_6074528_0 398720.MED217_11914 1.317e-53 196.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia,2XK11@283735|Leeuwenhoekiella 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer GDHHQS3_k127_6075211_2 215803.DB30_4494 5.228e-89 308.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,433V8@68525|delta/epsilon subdivisions,2X3MJ@28221|Deltaproteobacteria,2YWID@29|Myxococcales 28221|Deltaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 GDHHQS3_k127_6075211_6 522373.Smlt0140 5.261e-20 98.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1X61S@135614|Xanthomonadales 135614|Xanthomonadales T phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 GDHHQS3_k127_6075211_4 1004785.AMBLS11_09320 2.725e-56 200.0 COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,4670T@72275|Alteromonadaceae 1236|Gammaproteobacteria T GAF domain-containing protein yebR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 GDHHQS3_k127_6075211_5 713586.KB900536_gene595 3.393e-55 200.0 COG0500@1|root,COG2226@2|Bacteria,1QWW2@1224|Proteobacteria,1T361@1236|Gammaproteobacteria,1WY3X@135613|Chromatiales 135613|Chromatiales Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 GDHHQS3_k127_6075211_1 237609.PSAKL28_49280 7.034e-135 443.0 COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,1RMZR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate hutF - 3.5.3.13 ko:K05603 ko00340,map00340 - R02286 RC00682 ko00000,ko00001,ko01000 - - - Amidohydro_1 GDHHQS3_k127_6075211_3 322710.Avin_26150 2.563e-74 258.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RUSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E N-formylglutamate amidohydrolase hutG - 3.5.1.68,3.5.3.8 ko:K01458,ko:K01479 ko00340,ko00630,ko01100,map00340,map00630,map01100 M00045 R00525,R02285 RC00165,RC00221,RC00323,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase GDHHQS3_k127_6075211_0 472759.Nhal_3887 3.728e-168 553.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N GDHHQS3_k127_6075211_7 1442599.JAAN01000011_gene372 3.939e-09 58.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales 135614|Xanthomonadales NU pilus assembly protein pilp pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP GDHHQS3_k127_6105350_4 1223521.BBJX01000002_gene2859 2.506e-33 129.0 COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria,4AGHP@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM cytochrome c oxidase subunit II - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 GDHHQS3_k127_6105350_0 1223521.BBJX01000002_gene2860 2.877e-252 790.0 COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2VJ1N@28216|Betaproteobacteria,4AHFT@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Cytochrome c oxidase, subunit I cbaA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 GDHHQS3_k127_6105350_3 1244869.H261_01537 8.862e-64 229.0 COG1999@1|root,COG1999@2|Bacteria 2|Bacteria M signal sequence binding sco - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC GDHHQS3_k127_6105350_1 1123360.thalar_02888 1.522e-148 497.0 COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - Cytochrome_B,FlpD GDHHQS3_k127_6105350_6 596153.Alide_3613 2.09e-25 123.0 2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria,4AGT7@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6105350_5 1123360.thalar_02890 9.488e-32 128.0 COG2703@1|root,COG2703@2|Bacteria 2|Bacteria P oxygen carrier activity - - - ko:K07216 - - - - ko00000 - - - Hemerythrin GDHHQS3_k127_6105350_2 870187.Thini_0877 2.019e-99 334.0 COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,1SKBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I - - - - - - - - - - - - COX1 GDHHQS3_k127_6129829_1 889378.Spiaf_1296 7.18e-101 346.0 COG1502@1|root,COG1502@2|Bacteria,2J62N@203691|Spirochaetes 203691|Spirochaetes I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol clsD - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N GDHHQS3_k127_6129829_0 1283299.AUKG01000002_gene4029 7.438e-110 367.0 COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria 201174|Actinobacteria E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.87 ko:K07806,ko:K21337 ko00520,ko00523,ko01130,ko01503,ko02020,map00520,map00523,map01130,map01503,map02020 M00721,M00761 R07659,R11467 RC00006,RC01514,RC03445 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 GDHHQS3_k127_6129829_4 1379270.AUXF01000001_gene2051 9.324e-38 160.0 COG2124@1|root,COG2124@2|Bacteria 2|Bacteria Q cytochrome p450 - - - - - - - - - - - - p450 GDHHQS3_k127_6129829_3 103690.17132156 4.322e-49 190.0 COG1216@1|root,COG1216@2|Bacteria,1G2ZC@1117|Cyanobacteria,1HJ8R@1161|Nostocales 1117|Cyanobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_6129829_5 886293.Sinac_2707 3.361e-20 101.0 COG1215@1|root,COG1215@2|Bacteria,2J0YZ@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_6129829_2 102232.GLO73106DRAFT_00011930 1.488e-82 288.0 COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria 1117|Cyanobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_6129829_6 203907.Bfl178 4.948e-09 62.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,2837C@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria E Prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,5.4.99.5 ko:K04517,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R01715,R01728 RC00125,RC03116 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_2925 ACT,CM_2,PDH GDHHQS3_k127_6131595_2 1485544.JQKP01000015_gene2059 4.1e-16 82.0 COG3905@1|root,COG3905@2|Bacteria,1NDJP@1224|Proteobacteria,2VXH7@28216|Betaproteobacteria 28216|Betaproteobacteria K .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - - - - - - - - - - - GDHHQS3_k127_6131595_0 1357399.HMPREF2087_00823 3.095e-28 128.0 COG2755@1|root,COG2755@2|Bacteria,1R5F6@1224|Proteobacteria 1224|Proteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - GDHHQS3_k127_6131595_3 565045.NOR51B_2886 1.381e-08 57.0 COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,1SFPB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Death-on-curing protein doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic GDHHQS3_k127_6149177_3 247639.MGP2080_13984 3.091e-109 364.0 COG0477@1|root,COG2814@2|Bacteria,1PESQ@1224|Proteobacteria,1RU5F@1236|Gammaproteobacteria,1JAWC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_6149177_1 1121374.KB891592_gene2902 1.184e-198 643.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_6149177_5 1353528.DT23_18175 6.991e-59 213.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_6149177_7 379066.GAU_1183 1.097e-17 97.0 COG0664@1|root,COG0664@2|Bacteria,1ZTHA@142182|Gemmatimonadetes 142182|Gemmatimonadetes K helix_turn_helix, cAMP Regulatory protein - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding GDHHQS3_k127_6149177_4 1192034.CAP_2543 9.516e-68 250.0 COG0574@1|root,COG0574@2|Bacteria,1Q9MN@1224|Proteobacteria,434GW@68525|delta/epsilon subdivisions,2WYU9@28221|Deltaproteobacteria,2Z0MI@29|Myxococcales 28221|Deltaproteobacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - - - - - - - - - - PPDK_N GDHHQS3_k127_6149177_2 2074.JNYD01000015_gene4604 1.197e-127 427.0 COG3848@1|root,COG3848@2|Bacteria,2H2J1@201174|Actinobacteria 201174|Actinobacteria T PEP-utilising enzyme, mobile domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers GDHHQS3_k127_6149177_0 1384056.N787_09570 2.514e-230 732.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales 135614|Xanthomonadales E Prolyl oligopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N GDHHQS3_k127_6149177_9 1123073.KB899242_gene1378 3.285e-05 55.0 2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6149177_6 351348.Maqu_2298 2.581e-19 97.0 COG0484@1|root,COG4103@1|root,COG0484@2|Bacteria,COG4103@2|Bacteria,1NKPH@1224|Proteobacteria,1RTMM@1236|Gammaproteobacteria,46AN8@72275|Alteromonadaceae 1236|Gammaproteobacteria O Tellurite resistance protein TerB - - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB GDHHQS3_k127_6149177_8 1121943.KB900004_gene2917 1.297e-07 59.0 2FI32@1|root,349VU@2|Bacteria,1ND8X@1224|Proteobacteria,1SCWX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6187507_0 566466.NOR53_1771 1.263e-287 893.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1J8EP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A GDHHQS3_k127_6187507_1 1120953.AUBH01000007_gene1692 4.526e-273 842.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,46AGN@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B GDHHQS3_k127_6202956_4 926569.ANT_31630 1.57e-32 129.0 COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi 200795|Chloroflexi M PFAM UDP-glucose GDP-mannose dehydrogenase - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GDHHQS3_k127_6202956_0 926569.ANT_31640 7.446e-78 265.0 COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG GDHHQS3_k127_6202956_3 926569.ANT_31650 8.553e-35 140.0 COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi 200795|Chloroflexi K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 GDHHQS3_k127_6202956_1 926569.ANT_31660 4.862e-72 250.0 COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase M22 glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 GDHHQS3_k127_6202956_2 926569.ANT_31670 3.934e-58 206.0 COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi 200795|Chloroflexi S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE GDHHQS3_k127_6202956_5 926569.ANT_00690 1.569e-22 98.0 COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase 28 domain - - 2.4.1.46 ko:K03715 ko00561,ko01100,map00561,map01100 - R02691 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,MGDG_synth GDHHQS3_k127_6204405_3 1042377.AFPJ01000043_gene885 5.104e-126 417.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,466BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_6204405_0 565045.NOR51B_721 4.687e-137 457.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1S13F@1236|Gammaproteobacteria,1JB3R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_19,TPR_8 GDHHQS3_k127_6204405_1 565045.NOR51B_817 6.092e-129 423.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,1RXRI@1236|Gammaproteobacteria,1J6VS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_6204405_2 324602.Caur_1297 3.415e-128 422.0 COG0477@1|root,COG2814@2|Bacteria,2G6UA@200795|Chloroflexi 200795|Chloroflexi EGP TIGRFAM drug resistance transporter, Bcr CflA subfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 GDHHQS3_k127_6204405_4 935863.AWZR01000002_gene1070 4.479e-16 80.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18303 - M00642 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.17 - - ACR_tran GDHHQS3_k127_623776_2 1121033.AUCF01000003_gene3513 1.008e-86 294.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria,2JYWX@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GDHHQS3_k127_623776_4 1218076.BAYB01000048_gene5906 7.161e-46 171.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,1K3QS@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1993) - - - ko:K09983 - - - - ko00000 - - - DUF1993 GDHHQS3_k127_623776_3 1298593.TOL_1512 3.108e-60 210.0 COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria,1XPSI@135619|Oceanospirillales 135619|Oceanospirillales S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN GDHHQS3_k127_623776_6 1298593.TOL_1513 1.496e-22 98.0 COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,1SD4N@1236|Gammaproteobacteria,1XQDU@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial antitoxin of type II TA system, VapB - - - - - - - - - - - - VapB_antitoxin GDHHQS3_k127_623776_0 1122137.AQXF01000004_gene1727 4.468e-170 544.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the peptidase M24B family - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 GDHHQS3_k127_623776_1 1415778.JQMM01000001_gene1038 3.348e-146 473.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1J542@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S flavoproteins yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like GDHHQS3_k127_623776_5 1112274.KI911560_gene1036 1.799e-29 121.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2VP54@28216|Betaproteobacteria,2KM8U@206350|Nitrosomonadales 206350|Nitrosomonadales I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase GDHHQS3_k127_6241539_4 338966.Ppro_0014 7.249e-30 121.0 COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase GDHHQS3_k127_6241539_0 338969.Rfer_4073 4.131e-218 695.0 COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria 28216|Betaproteobacteria P Cytochrome c554 and c-prime - - - - - - - - - - - - - GDHHQS3_k127_6241539_3 338969.Rfer_2735 1.393e-36 148.0 COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria 1224|Proteobacteria T response regulator - - - - - - - - - - - - Response_reg GDHHQS3_k127_6241539_2 338969.Rfer_2740 9.875e-74 274.0 COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria 1224|Proteobacteria C cytochrome cbcB - - - - - - - - - - - Ni_hydr_CYTB GDHHQS3_k127_6241539_1 338969.Rfer_2739 5.264e-97 343.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1 GDHHQS3_k127_6264063_2 765911.Thivi_2682 8.011e-48 178.0 COG2227@1|root,COG2227@2|Bacteria,1QZX6@1224|Proteobacteria,1S4AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Methylase involved in ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_6264063_0 1384056.N787_09330 4.865e-206 665.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X3FJ@135614|Xanthomonadales 135614|Xanthomonadales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS GDHHQS3_k127_6264063_1 472759.Nhal_1290 1.792e-102 352.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales 135613|Chromatiales L TIGRFAM ATP-dependent helicase HrpA - - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind GDHHQS3_k127_6290873_1 493475.GARC_1693 1.236e-62 218.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,465G8@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6,4.1.1.75 ko:K01652,ko:K12253 ko00290,ko00330,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00330,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R03178,R04672,R04673,R08648 RC00027,RC00106,RC00506,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_6290873_2 948106.AWZT01000096_gene4620 2.297e-31 129.0 COG1028@1|root,COG1028@2|Bacteria,1P3AE@1224|Proteobacteria,2VN49@28216|Betaproteobacteria,1KGKH@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Polysaccharide biosynthesis protein - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_6290873_0 383372.Rcas_3215 1.208e-98 333.0 COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia 32061|Chloroflexia S PFAM oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA GDHHQS3_k127_6290873_3 1123276.KB893301_gene4190 1.42e-14 78.0 COG1028@1|root,COG1028@2|Bacteria,4PPND@976|Bacteroidetes,47YR9@768503|Cytophagia 976|Bacteroidetes IQ Fungal family of unknown function (DUF1776) - - - - - - - - - - - - adh_short GDHHQS3_k127_6296342_0 1121374.KB891576_gene671 6.979e-180 569.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed paaJ GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K00632,ko:K02615 ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N GDHHQS3_k127_6296342_1 1122201.AUAZ01000037_gene3842 9.407e-114 373.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria,465J5@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase paaG GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475 ECH_1 GDHHQS3_k127_6296342_2 1232683.ADIMK_2821 1.646e-75 256.0 COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,1RYPQ@1236|Gammaproteobacteria,469IT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial transferase hexapeptide (six repeats) paaY GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009437,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0044237,GO:0071704,GO:0097164,GO:1901564 - ko:K02617,ko:K08279 - - - - ko00000 - - - Hexapep GDHHQS3_k127_6306504_1 1122603.ATVI01000005_gene3549 3.098e-62 224.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1X6TU@135614|Xanthomonadales 135614|Xanthomonadales D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 GDHHQS3_k127_6306504_0 1122603.ATVI01000005_gene3550 1.678e-130 431.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XCFT@135614|Xanthomonadales 135614|Xanthomonadales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB GDHHQS3_k127_6306504_2 1122604.JONR01000015_gene139 2.119e-59 212.0 COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1X7KH@135614|Xanthomonadales 135614|Xanthomonadales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB GDHHQS3_k127_6306504_6 572480.Arnit_0564 2.201e-31 128.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,42SKN@68525|delta/epsilon subdivisions 1224|Proteobacteria U PFAM Biopolymer transport protein ExbD TolR exbD - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD GDHHQS3_k127_6306504_3 1122604.JONR01000015_gene137 1.096e-51 188.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1X7VH@135614|Xanthomonadales 135614|Xanthomonadales U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD GDHHQS3_k127_6306504_5 414684.RC1_0803 2.383e-32 133.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,2UEEK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C GDHHQS3_k127_6306504_4 1265313.HRUBRA_01305 9.962e-34 142.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1J575@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - ANAPC3,TPR_16,TPR_8 GDHHQS3_k127_6320916_4 382245.ASA_3262 1.956e-65 228.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1Y51Z@135624|Aeromonadales 135624|Aeromonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C GDHHQS3_k127_6320916_1 1121935.AQXX01000093_gene3416 9.94e-145 472.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1XIC6@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bkdA1 - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh GDHHQS3_k127_6320916_0 1121374.KB891576_gene736 2.543e-172 549.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bkdA2 - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C GDHHQS3_k127_6320916_2 1123257.AUFV01000010_gene3202 5.271e-121 401.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RMJR@1236|Gammaproteobacteria,1X3BI@135614|Xanthomonadales 135614|Xanthomonadales C e3 binding domain - - - - - - - - - - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding GDHHQS3_k127_6320916_6 1173025.GEI7407_1777 1.963e-05 56.0 COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales 1117|Cyanobacteria O PDZ domain (Also known as DHR or GLGF) htrA - - - - - - - - - - - PDZ_2,Trypsin_2 GDHHQS3_k127_6320916_5 1215092.PA6_007_01260 1.568e-55 207.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1YEZU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E GDSL-like Lipase/Acylhydrolase tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 GDHHQS3_k127_6320916_3 1442599.JAAN01000010_gene211 1.106e-83 286.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_6328377_1 450851.PHZ_c2260 5.137e-25 107.0 COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2U7MF@28211|Alphaproteobacteria,2KGXQ@204458|Caulobacterales 204458|Caulobacterales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg GDHHQS3_k127_6328377_0 1496688.ER33_11550 4.829e-74 254.0 28PFD@1|root,2ZC6I@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6336387_11 383407.XOC_1170 3.294e-26 115.0 COG1399@1|root,COG1399@2|Bacteria,1PCKS@1224|Proteobacteria,1SXPD@1236|Gammaproteobacteria,1X6HR@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 GDHHQS3_k127_6336387_13 765912.Thimo_2384 1.988e-24 103.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1WZ7D@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p GDHHQS3_k127_6336387_6 519989.ECTPHS_10366 1.058e-86 298.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis GDHHQS3_k127_6336387_1 935863.AWZR01000006_gene1221 3.527e-140 452.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1X3CE@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C GDHHQS3_k127_6336387_3 314292.VAS14_05248 2.807e-99 332.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1XTJB@135623|Vibrionales 135623|Vibrionales I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 GDHHQS3_k127_6336387_5 1123253.AUBD01000006_gene839 5.653e-90 306.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1X475@135614|Xanthomonadales 135614|Xanthomonadales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 GDHHQS3_k127_6336387_10 1122185.N792_04885 9.251e-36 136.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales 135614|Xanthomonadales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding GDHHQS3_k127_6336387_0 1163407.UU7_02852 5.018e-177 563.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3AN@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt GDHHQS3_k127_6336387_2 1123261.AXDW01000004_gene2871 6.487e-133 439.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales 135614|Xanthomonadales EH component I pabB - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind GDHHQS3_k127_6336387_7 1163407.UU7_02862 9.563e-67 237.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1X65C@135614|Xanthomonadales 135614|Xanthomonadales EH Amino-transferase class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 GDHHQS3_k127_6336387_4 743721.Psesu_1999 9.726e-91 313.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1X31Z@135614|Xanthomonadales 135614|Xanthomonadales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG GDHHQS3_k127_6336387_8 351746.Pput_3795 1.008e-64 227.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1YVBH@136845|Pseudomonas putida group 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin GDHHQS3_k127_6336387_9 1123253.AUBD01000006_gene832 8.969e-49 188.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1X34V@135614|Xanthomonadales 135614|Xanthomonadales L the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 GDHHQS3_k127_6336387_12 1384056.N787_08135 7.918e-25 104.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1X6W7@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ GDHHQS3_k127_6336677_6 292564.Cyagr_2281 8.296e-66 229.0 COG1235@1|root,COG2199@1|root,COG2203@1|root,COG1235@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1G1UR@1117|Cyanobacteria,22TIW@167375|Cyanobium 1117|Cyanobacteria T Beta-lactamase superfamily domain - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 GDHHQS3_k127_6336677_1 269799.Gmet_2131 1.817e-206 652.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WIUM@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_6336677_3 1458427.BAWN01000013_gene920 1.798e-125 415.0 COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,2VQ1T@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4143) - - - - - - - - - - - - AAA_14,DUF4143 GDHHQS3_k127_6336677_7 570967.JMLV01000037_gene1282 7.613e-32 128.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2UFXF@28211|Alphaproteobacteria,2JU2Z@204441|Rhodospirillales 204441|Rhodospirillales K Helix-turn-helix XRE-family like proteins - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 GDHHQS3_k127_6336677_8 449447.MAE_58320 9.296e-31 123.0 COG3549@1|root,COG3549@2|Bacteria,1GAID@1117|Cyanobacteria 1117|Cyanobacteria S Plasmid maintenance system killer - - - ko:K07334 - - - - ko00000,ko02048 - - - - GDHHQS3_k127_6336677_12 1122603.ATVI01000005_gene3860 6.812e-09 66.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - - GDHHQS3_k127_6336677_11 2340.JV46_08960 4.361e-09 60.0 28PZQ@1|root,2ZCIX@2|Bacteria,1RA7M@1224|Proteobacteria,1S25R@1236|Gammaproteobacteria,1JBES@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S EF hand - - - - - - - - - - - - EF-hand_5 GDHHQS3_k127_6336677_9 1266925.JHVX01000001_gene2466 2.568e-23 106.0 COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,2WG5K@28216|Betaproteobacteria,37390@32003|Nitrosomonadales 28216|Betaproteobacteria S bacterial OsmY and nodulation domain - - - ko:K04065 - - - - ko00000 - - - BON GDHHQS3_k127_6336677_0 1095769.CAHF01000011_gene2198 2.412e-278 863.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,472FB@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C GDHHQS3_k127_6336677_4 204773.HEAR1090 1.464e-119 391.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,47238@75682|Oxalobacteraceae 28216|Betaproteobacteria H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N GDHHQS3_k127_6336677_2 1005048.CFU_1381 2.351e-184 582.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,47296@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA GDHHQS3_k127_6336677_5 472759.Nhal_2003 6.473e-82 286.0 COG5505@1|root,COG5505@2|Bacteria,1RAF4@1224|Proteobacteria,1S8PC@1236|Gammaproteobacteria,1WZZD@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 GDHHQS3_k127_6336677_10 1118235.CAJH01000027_gene1910 2.071e-20 92.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,1X55T@135614|Xanthomonadales 135614|Xanthomonadales V Beta-lactamase ampC2 - - - - - - - - - - - Beta-lactamase,DUF3471 GDHHQS3_k127_63499_1 1304275.C41B8_11825 1.509e-196 626.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0050896,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 GDHHQS3_k127_63499_3 187272.Mlg_1358 1.307e-187 596.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1WW57@135613|Chromatiales 135613|Chromatiales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 GDHHQS3_k127_63499_6 396588.Tgr7_1850 1.057e-89 312.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1WYFQ@135613|Chromatiales 135613|Chromatiales S A domain family that is part of the cupin metalloenzyme superfamily. - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 GDHHQS3_k127_63499_0 1163407.UU7_03062 0.0 1107.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1X4NM@135614|Xanthomonadales 135614|Xanthomonadales C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr GDHHQS3_k127_63499_4 767434.Fraau_1675 2.068e-139 452.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1X3Y6@135614|Xanthomonadales 135614|Xanthomonadales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding GDHHQS3_k127_63499_2 1500890.JQNL01000001_gene485 2.385e-192 611.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3A1@135614|Xanthomonadales 135614|Xanthomonadales C E3 component of 2-oxoglutarate dehydrogenase complex ldp - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim GDHHQS3_k127_63499_5 1384054.N790_14475 6.157e-127 413.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1X33P@135614|Xanthomonadales 135614|Xanthomonadales C Quinone oxidoreductase - - - - - - - - - - - - ADH_N,ADH_zinc_N GDHHQS3_k127_6366994_2 1123073.KB899243_gene599 1.329e-43 162.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S852@1236|Gammaproteobacteria,1XCMB@135614|Xanthomonadales 135614|Xanthomonadales S SufE protein probably involved in Fe-S center assembly - - - ko:K02426 - - - - ko00000 - - - SufE GDHHQS3_k127_6366994_0 1384056.N787_11800 6.079e-180 575.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1X2ZK@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e GDHHQS3_k127_6366994_1 1537994.JQFW01000015_gene1589 4.179e-85 294.0 COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,465D3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Splits dipeptides with a prolyl residue in the C- terminal position pepQ GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 GDHHQS3_k127_6376499_1 1209072.ALBT01000031_gene1854 7.101e-134 439.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1FG23@10|Cellvibrio 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N GDHHQS3_k127_6376499_5 1385517.N800_15095 1.802e-30 123.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - - - - - - - - - - HTH_5 GDHHQS3_k127_6376499_3 913325.N799_05720 8.778e-93 314.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1X3E4@135614|Xanthomonadales 135614|Xanthomonadales S Zn-dependent hydrolases including glyoxylases - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_6376499_0 983920.Y88_2418 1.232e-181 577.0 COG0446@1|root,COG0446@2|Bacteria,1QSG6@1224|Proteobacteria,2TUP1@28211|Alphaproteobacteria,2K2NT@204457|Sphingomonadales 204457|Sphingomonadales S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 GDHHQS3_k127_6376499_2 1265313.HRUBRA_00870 4.064e-99 343.0 COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1SYRU@1236|Gammaproteobacteria,1JBZC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 GDHHQS3_k127_6376499_4 1117647.M5M_15680 1.336e-84 284.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J4WC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_6378288_0 1123253.AUBD01000006_gene794 3.293e-111 362.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1X491@135614|Xanthomonadales 135614|Xanthomonadales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE GDHHQS3_k127_6378288_1 1049564.TevJSym_ab01230 5.626e-92 309.0 COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 GDHHQS3_k127_6378288_2 314278.NB231_01074 7.924e-34 141.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales 135613|Chromatiales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C GDHHQS3_k127_6378288_4 1123073.KB899244_gene434 8.316e-09 59.0 COG5508@1|root,COG5508@2|Bacteria,1QBN7@1224|Proteobacteria,1SGI9@1236|Gammaproteobacteria,1X8XH@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1674) - - - - - - - - - - - - DUF1674 GDHHQS3_k127_6378288_3 1122603.ATVI01000013_gene1342 1.503e-09 59.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,1SBJ7@1236|Gammaproteobacteria,1X7WB@135614|Xanthomonadales 135614|Xanthomonadales C Succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt GDHHQS3_k127_6401002_1 765910.MARPU_11595 2.118e-183 583.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N GDHHQS3_k127_6401002_3 1500890.JQNL01000001_gene3243 7.812e-45 164.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1X72N@135614|Xanthomonadales 135614|Xanthomonadales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS GDHHQS3_k127_6401002_2 1123073.KB899244_gene331 6.906e-149 480.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1X446@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans GDHHQS3_k127_6401002_4 395493.BegalDRAFT_2787 8.498e-37 147.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,460TW@72273|Thiotrichales 72273|Thiotrichales S High frequency lysogenization protein hflD homolog hflD - - ko:K07153 - - - - ko00000 - - - DUF489 GDHHQS3_k127_6401002_0 1304275.C41B8_02437 5.85e-280 873.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547 Aconitase,Aconitase_C GDHHQS3_k127_6436403_12 1384056.N787_10945 3.651e-31 124.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RXZ5@1236|Gammaproteobacteria,1X4RH@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulator rbcR - - - - - - - - - - - HTH_1,LysR_substrate GDHHQS3_k127_6436403_0 765913.ThidrDRAFT_0180 2.114e-180 574.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales 135613|Chromatiales U Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp GDHHQS3_k127_6436403_8 1411685.U062_00841 1.023e-49 183.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II GDHHQS3_k127_6436403_14 1178482.BJB45_20095 1.235e-15 85.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XKPZ@135619|Oceanospirillales 135619|Oceanospirillales C cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 GDHHQS3_k127_6436403_11 1500890.JQNL01000001_gene2278 3.314e-38 151.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1X6KI@135614|Xanthomonadales 135614|Xanthomonadales S Acyl carrier protein phosphodiesterase - - - - - - - - - - - - ACP_PD GDHHQS3_k127_6436403_4 1163408.UU9_14400 3.69e-75 266.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1X4H4@135614|Xanthomonadales 135614|Xanthomonadales S Alpha beta - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 GDHHQS3_k127_6436403_1 395493.BegalDRAFT_1809 5.043e-113 376.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,460G7@72273|Thiotrichales 72273|Thiotrichales D AFG1-like ATPase zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase GDHHQS3_k127_6436403_6 187272.Mlg_2433 1.91e-56 209.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales 135613|Chromatiales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 GDHHQS3_k127_6436403_7 1442599.JAAN01000044_gene2880 4.402e-51 189.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X6Y9@135614|Xanthomonadales 135614|Xanthomonadales S Competence protein - - - - - - - - - - - - Pribosyltran GDHHQS3_k127_6436403_3 247639.MGP2080_03335 1.652e-94 322.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - iZ_1308.Z5639 UbiA GDHHQS3_k127_6436403_2 1385515.N791_06850 7.258e-104 344.0 COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales 135614|Xanthomonadales L Preprotein translocase subunit TatD tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase GDHHQS3_k127_6436403_13 1265313.HRUBRA_00686 5.995e-30 124.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1JBFQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT GDHHQS3_k127_6436403_9 716928.AJQT01000067_gene3879 2.499e-42 165.0 COG3900@1|root,COG3900@2|Bacteria,1NXBA@1224|Proteobacteria,2U3G3@28211|Alphaproteobacteria,4B7F5@82115|Rhizobiaceae 28211|Alphaproteobacteria M Predicted periplasmic protein (DUF2092) - - - - - - - - - - - - DUF2092,OmpA GDHHQS3_k127_6436403_15 159450.NH14_00665 6.021e-05 50.0 2E8Y7@1|root,3337X@2|Bacteria,1NBJG@1224|Proteobacteria,2W2J4@28216|Betaproteobacteria,1KA7X@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6436403_5 765911.Thivi_3668 1.398e-65 229.0 COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria,1X1C2@135613|Chromatiales 135613|Chromatiales S Patatin-like phospholipase - - - - - - - - - - - - Patatin GDHHQS3_k127_6436403_10 640511.BC1002_5548 9.273e-42 158.0 2E5SP@1|root,330H2@2|Bacteria,1NDBY@1224|Proteobacteria,2VXDV@28216|Betaproteobacteria,1K76Z@119060|Burkholderiaceae 28216|Betaproteobacteria S YMGG-like Gly-zipper - - - - - - - - - - - - Gly-zipper_YMGG GDHHQS3_k127_644037_0 314285.KT71_12610 1.431e-303 939.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1J9RR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept GDHHQS3_k127_6441465_2 935848.JAEN01000010_gene1075 2.957e-27 117.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2TTAB@28211|Alphaproteobacteria,2PV0A@265|Paracoccus 28211|Alphaproteobacteria F Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_6441465_0 1123366.TH3_03000 2.329e-149 487.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria,2JR7F@204441|Rhodospirillales 204441|Rhodospirillales F CO dehydrogenase flavoprotein C-terminal domain xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 GDHHQS3_k127_6441465_1 1286093.C266_20289 6.479e-48 176.0 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2VUG8@28216|Betaproteobacteria,1K7R7@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily uraH - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin GDHHQS3_k127_6460336_2 1002340.AFCF01000028_gene3148 6.196e-63 221.0 COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,34E23@302485|Phaeobacter 28211|Alphaproteobacteria S Alkylhydroperoxidase AhpD family core domain protein - - - - - - - - - - - - CMD GDHHQS3_k127_6460336_1 1273538.G159_17110 8.43e-87 300.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,26FJQ@186818|Planococcaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 GDHHQS3_k127_6460336_3 1178482.BJB45_14285 2.02e-28 119.0 COG3474@1|root,COG3474@2|Bacteria,1QZ7V@1224|Proteobacteria,1TI9S@1236|Gammaproteobacteria,1XPX9@135619|Oceanospirillales 135619|Oceanospirillales C cytochrome - - - - - - - - - - - - - GDHHQS3_k127_6460336_0 1283300.ATXB01000002_gene2988 3.913e-197 622.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XGME@135618|Methylococcales 135618|Methylococcales S Mo-co oxidoreductase dimerisation domain - - - ko:K17225 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Mo-co_dimer,Oxidored_molyb GDHHQS3_k127_6460336_4 396588.Tgr7_2202 2.388e-15 77.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1WXF3@135613|Chromatiales 135613|Chromatiales I Membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X GDHHQS3_k127_6513385_0 83406.HDN1F_19940 1.873e-185 581.0 COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,1RPYS@1236|Gammaproteobacteria,1J6N5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S FAD binding domain - - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 GDHHQS3_k127_6513385_1 1268622.AVS7_03385 2.982e-144 461.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2VV5Q@28216|Betaproteobacteria,4AF8V@80864|Comamonadaceae 28216|Betaproteobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF GDHHQS3_k127_6513385_2 1215114.BBIU01000007_gene1159 2.479e-89 304.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh GDHHQS3_k127_6528857_0 572477.Alvin_1616 1.02e-158 508.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b GDHHQS3_k127_6528857_1 658187.LDG_6503 8.286e-41 159.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1JCRY@118969|Legionellales 118969|Legionellales S Belongs to the BI1 family yccA - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I GDHHQS3_k127_6528857_2 1168059.KB899087_gene1061 3.062e-06 52.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae 28211|Alphaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom GDHHQS3_k127_6528857_3 1191299.AJYX01000052_gene1553 0.0002999 44.0 COG1986@1|root,COG1986@2|Bacteria,1RG2E@1224|Proteobacteria,1S5QG@1236|Gammaproteobacteria,1XUT8@135623|Vibrionales 135623|Vibrionales F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions yjjX GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - - - - - - - - - - NTPase_I-T GDHHQS3_k127_65703_5 323261.Noc_2182 1.835e-20 95.0 COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,1S0H9@1236|Gammaproteobacteria,1X247@135613|Chromatiales 135613|Chromatiales GM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane GDHHQS3_k127_65703_0 1384056.N787_08905 1.837e-122 406.0 COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1X5H8@135614|Xanthomonadales 135614|Xanthomonadales GM ABC transporter - - - - - - - - - - - - ABC_tran GDHHQS3_k127_65703_1 1384056.N787_08910 3.178e-77 272.0 COG1216@1|root,COG1216@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria,1X4AI@135614|Xanthomonadales 135614|Xanthomonadales S glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_65703_2 1123073.KB899241_gene3172 8.537e-67 239.0 COG2227@1|root,COG2227@2|Bacteria,1N6SE@1224|Proteobacteria,1SCC1@1236|Gammaproteobacteria,1X6AF@135614|Xanthomonadales 135614|Xanthomonadales H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_65703_3 344747.PM8797T_20274 1.118e-50 190.0 COG1216@1|root,COG1216@2|Bacteria,2J0AR@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 GDHHQS3_k127_65703_4 1045855.DSC_15570 1.207e-40 168.0 COG0451@1|root,COG0451@2|Bacteria,1RB7F@1224|Proteobacteria,1S6UB@1236|Gammaproteobacteria,1X5HR@135614|Xanthomonadales 135614|Xanthomonadales GM epimerase - - - - - - - - - - - - Epimerase GDHHQS3_k127_663049_3 913325.N799_13740 2.327e-97 327.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1X3KG@135614|Xanthomonadales 135614|Xanthomonadales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 GDHHQS3_k127_663049_0 1121035.AUCH01000017_gene2306 2.114e-145 471.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales 206389|Rhodocyclales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom GDHHQS3_k127_663049_6 1033802.SSPSH_001098 3.895e-42 167.0 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 GDHHQS3_k127_663049_4 1234364.AMSF01000027_gene3470 1.364e-89 302.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1X31M@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf GDHHQS3_k127_663049_5 765913.ThidrDRAFT_3537 3.383e-73 250.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1WY5S@135613|Chromatiales 135613|Chromatiales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF GDHHQS3_k127_663049_1 1163407.UU7_00847 4.604e-107 351.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1X4J2@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase GDHHQS3_k127_663049_2 396588.Tgr7_1160 8.475e-101 338.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales 135613|Chromatiales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS GDHHQS3_k127_663049_7 1384056.N787_10210 8.018e-25 111.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1X2XU@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 GDHHQS3_k127_6652981_1 1121013.P873_03325 1.419e-74 253.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1X3XK@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT GDHHQS3_k127_6652981_0 751994.AGIG01000030_gene763 1.404e-270 844.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1J503@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn GDHHQS3_k127_6731239_5 1307759.JOMJ01000005_gene8 2.232e-10 65.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3,DUF1080,Phenol_MetA_deg GDHHQS3_k127_6731239_3 439235.Dalk_4800 3.747e-133 440.0 COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,43CSJ@68525|delta/epsilon subdivisions,2X807@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function(DUF2779) - - - - - - - - - - - - DUF2779 GDHHQS3_k127_6731239_4 565045.NOR51B_754 1.163e-40 156.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity yrgI - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GDHHQS3_k127_6731239_0 864051.BurJ1DRAFT_4547 3.365e-321 989.0 COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales 28216|Betaproteobacteria C NADPH-dependent glutamate synthase beta - - - - - - - - - - - - Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3 GDHHQS3_k127_6731239_2 395495.Lcho_2151 1.769e-185 582.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,1KJCA@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain porB - 1.2.1.58,1.2.7.1 ko:K00170,ko:K18356 ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R02450,R08034 RC00004,RC00250,RC02742,RC02833,RC02860 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4_11,Fer4_6,TPP_enzyme_C GDHHQS3_k127_6731239_1 864051.BurJ1DRAFT_4545 2.306e-204 639.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,1KK3S@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Pyruvate:ferredoxin oxidoreductase core domain II porA - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N GDHHQS3_k127_6748692_0 316274.Haur_0869 9.598e-06 49.0 28IKZ@1|root,2Z8MJ@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1702) - - - ko:K21161 ko01059,ko01130,map01059,map01130 M00824 - - ko00000,ko00001,ko00002 - - - DUF1702 GDHHQS3_k127_6749107_7 925409.KI911562_gene2676 2.612e-29 116.0 COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_6749107_3 1123393.KB891328_gene699 1.207e-117 388.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,1KRZ5@119069|Hydrogenophilales 119069|Hydrogenophilales F Dihydroorotate dehydrogenase - - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh GDHHQS3_k127_6749107_6 1118235.CAJH01000010_gene637 1.458e-92 317.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1X3P6@135614|Xanthomonadales 135614|Xanthomonadales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C GDHHQS3_k127_6749107_1 1122137.AQXF01000001_gene3093 9.171e-171 554.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Peptidase, M28 - - - - - - - - - - - - PA,Peptidase_M28 GDHHQS3_k127_6749107_0 1211114.ALIP01000007_gene2601 6.203e-197 620.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_6749107_4 1380387.JADM01000010_gene3938 2.844e-115 379.0 2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,1XIXA@135619|Oceanospirillales 135619|Oceanospirillales S 5'-nucleotidase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase GDHHQS3_k127_6749107_8 981383.AEWH01000026_gene2851 1.34e-20 106.0 COG3173@1|root,COG3173@2|Bacteria,1VH64@1239|Firmicutes,4HQ3F@91061|Bacilli 91061|Bacilli S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH GDHHQS3_k127_6749107_5 1123073.KB899242_gene1144 1.229e-95 319.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1X4HU@135614|Xanthomonadales 135614|Xanthomonadales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP ppnK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase GDHHQS3_k127_6749107_2 1385515.N791_14135 1.076e-129 427.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N GDHHQS3_k127_6752723_2 1366050.N234_31975 1.215e-103 341.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VKKS@28216|Betaproteobacteria,1K3P0@119060|Burkholderiaceae 28216|Betaproteobacteria C oxidase, subunit coxP - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 GDHHQS3_k127_6752723_4 1121935.AQXX01000131_gene2882 7.655e-41 153.0 COG5605@1|root,COG5605@2|Bacteria,1RH8B@1224|Proteobacteria,1S95E@1236|Gammaproteobacteria,1XPY2@135619|Oceanospirillales 135619|Oceanospirillales S Prokaryotic Cytochrome C oxidase subunit IV - - - - - - - - - - - - COX4_pro GDHHQS3_k127_6752723_5 1088721.NSU_3671 9.021e-25 110.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales 28211|Alphaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - Glutaredoxin,PALP GDHHQS3_k127_6752723_1 926569.ANT_27020 2.243e-122 407.0 COG1816@1|root,COG1816@2|Bacteria 2|Bacteria F deaminase activity add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780 A_deaminase GDHHQS3_k127_6752723_3 1120963.KB894505_gene3714 1.613e-92 318.0 COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,1RXQ8@1236|Gammaproteobacteria,2Q4HS@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria Q Phytanoyl-CoA dioxygenase (PhyH) - - 1.14.11.18 ko:K00477 ko04146,map04146 - - - ko00000,ko00001,ko01000 - - - PhyH GDHHQS3_k127_6752723_0 519989.ECTPHS_03592 2.658e-179 586.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales 135613|Chromatiales Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GDHHQS3_k127_6754035_1 1123240.ATVO01000005_gene1908 1.178e-86 297.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2K3D5@204457|Sphingomonadales 204457|Sphingomonadales C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN GDHHQS3_k127_6754035_6 1454004.AW11_00035 3.1e-20 98.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - - - - - - - - - - Usp GDHHQS3_k127_6754035_0 572477.Alvin_1243 4.856e-167 544.0 COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1WXUR@135613|Chromatiales 135613|Chromatiales P PFAM Na Picotransporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU GDHHQS3_k127_6754035_4 314285.KT71_06262 1.918e-60 235.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT7@1236|Gammaproteobacteria,1JBPX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - GDHHQS3_k127_6754035_2 1122604.JONR01000031_gene1279 4.572e-74 274.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T5SE@1236|Gammaproteobacteria,1XDE6@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 GDHHQS3_k127_6754035_3 722419.PH505_ar00570 2.527e-62 224.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RS8E@1236|Gammaproteobacteria,2Q1N0@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - 1.14.19.20 ko:K00227 ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130 M00101,M00102 R07215,R07486,R07491,R07505 RC00904 ko00000,ko00001,ko00002,ko01000 - - - FA_hydroxylase GDHHQS3_k127_6764166_1 886293.Sinac_5166 2.181e-136 443.0 COG0451@1|root,COG0451@2|Bacteria,2IZ0M@203682|Planctomycetes 203682|Planctomycetes GM Polysaccharide biosynthesis protein - - 1.1.1.203 ko:K18981 ko00053,map00053 - R10841 RC00066 ko00000,ko00001,ko01000 - - - Epimerase GDHHQS3_k127_6764166_0 870187.Thini_1689 2.513e-215 684.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4607X@72273|Thiotrichales 72273|Thiotrichales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C GDHHQS3_k127_6764166_2 545264.KB898751_gene2524 1.711e-63 222.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1WYBE@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 GDHHQS3_k127_6768800_7 1129794.C427_3114 1.067e-35 145.0 COG2863@1|root,COG2863@2|Bacteria,1QXWH@1224|Proteobacteria,1T3IQ@1236|Gammaproteobacteria,468V6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,ThuA GDHHQS3_k127_6768800_0 565045.NOR51B_1833 8.375e-199 632.0 COG2010@1|root,COG3420@1|root,COG2010@2|Bacteria,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,1T2I7@1236|Gammaproteobacteria,1J4SI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG3420 Nitrous oxidase accessory protein - - - - - - - - - - - - Beta_helix,NosD GDHHQS3_k127_6768800_2 565045.NOR51B_1548 1.147e-146 477.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1J7GB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1858 Cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C GDHHQS3_k127_6768800_8 84531.JMTZ01000020_gene3692 3.207e-27 116.0 COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,1SF8F@1236|Gammaproteobacteria,1X7JH@135614|Xanthomonadales 135614|Xanthomonadales S MAPEG family - - - - - - - - - - - - MAPEG GDHHQS3_k127_6768800_6 1385517.N800_12720 1.613e-48 177.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S69Q@1236|Gammaproteobacteria,1X8MY@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA GDHHQS3_k127_6768800_3 1177181.T9A_01867 1.829e-98 327.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,1XI06@135619|Oceanospirillales 135619|Oceanospirillales L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG GDHHQS3_k127_6768800_5 1231391.AMZF01000017_gene154 3.927e-70 240.0 COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,2W22Q@28216|Betaproteobacteria,3T79J@506|Alcaligenaceae 28216|Betaproteobacteria FJ MafB19-like deaminase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 GDHHQS3_k127_6768800_1 1123278.KB893488_gene6138 1.499e-189 607.0 COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 GDHHQS3_k127_6768800_4 1089552.KI911559_gene1088 3.47e-79 267.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2JQ3S@204441|Rhodospirillales 204441|Rhodospirillales S Carbon-nitrogen hydrolase - - 3.5.1.6 ko:K01431 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R00905,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase GDHHQS3_k127_6773197_5 1245471.PCA10_07270 1.715e-91 308.0 COG2823@1|root,COG2823@2|Bacteria,1MY8V@1224|Proteobacteria,1S2D4@1236|Gammaproteobacteria,1YFBY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S bacterial OsmY and nodulation domain - - - ko:K04065 - - - - ko00000 - - - BON GDHHQS3_k127_6773197_0 748280.NH8B_2742 1.374e-223 706.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,2KQD0@206351|Neisseriales 206351|Neisseriales I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 GDHHQS3_k127_6773197_12 697282.Mettu_0548 3.426e-26 112.0 2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Family of unknown function (DUF5329) - - - - - - - - - - - - DUF5329 GDHHQS3_k127_6773197_16 1165841.SULAR_02563 2.056e-14 76.0 2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6773197_10 1249480.B649_08035 9.74e-41 156.0 2ATZM@1|root,31JJE@2|Bacteria,1RIFX@1224|Proteobacteria,431W9@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6773197_3 748247.AZKH_2012 3.368e-150 497.0 COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria,2VIKR@28216|Betaproteobacteria,2KVI1@206389|Rhodocyclales 28216|Betaproteobacteria PT iron ion homeostasis - - - - - - - - - - - - FecR GDHHQS3_k127_6773197_1 76114.ebA6098 1.707e-196 621.0 COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,2KUTD@206389|Rhodocyclales 206389|Rhodocyclales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger GDHHQS3_k127_6773197_17 1123073.KB899242_gene1378 2.822e-10 75.0 2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6773197_7 211165.AJLN01000085_gene1672 3.817e-71 249.0 COG0605@1|root,COG0605@2|Bacteria,1G0VH@1117|Cyanobacteria,1JJAI@1189|Stigonemataceae 1117|Cyanobacteria P Iron/manganese superoxide dismutases, alpha-hairpin domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N GDHHQS3_k127_6773197_15 1287276.X752_15530 8.614e-20 91.0 COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria,43M7Y@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin GDHHQS3_k127_6773197_20 1236542.BALM01000005_gene2624 1.752e-06 59.0 2EQSJ@1|root,33ICE@2|Bacteria,1NMDR@1224|Proteobacteria,1SIP0@1236|Gammaproteobacteria,2QDWY@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6773197_11 247634.GPB2148_2591 3.102e-36 149.0 COG3764@1|root,COG3764@2|Bacteria,1N05G@1224|Proteobacteria,1SB22@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG3764 Sortase (surface protein transpeptidase) - - - - - - - - - - - - Sortase GDHHQS3_k127_6773197_4 1301098.PKB_5465 6.392e-115 374.0 COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K PFAM Cyclic nucleotide-binding - - - - - - - - - - - - HTH_Crp_2,cNMP_binding GDHHQS3_k127_6773197_6 1245471.PCA10_07180 1.859e-74 259.0 COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,1S488@1236|Gammaproteobacteria,1YFC5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2 GDHHQS3_k127_6773197_8 1123269.NX02_24455 2.093e-62 226.0 COG2162@1|root,COG2162@2|Bacteria,1RDF3@1224|Proteobacteria,2U7QG@28211|Alphaproteobacteria,2K15A@204457|Sphingomonadales 204457|Sphingomonadales Q Belongs to the arylamine N-acetyltransferase family nat - 2.3.1.118 ko:K00675 - - - - ko00000,ko01000 - - - Acetyltransf_2 GDHHQS3_k127_6773197_2 1123503.KB908056_gene1593 1.561e-176 561.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2KFJN@204458|Caulobacterales 204458|Caulobacterales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N GDHHQS3_k127_6773197_9 449447.MAE_43070 3.494e-50 182.0 COG1487@1|root,COG1487@2|Bacteria,1G63I@1117|Cyanobacteria 1117|Cyanobacteria S nucleic acid-binding protein contains PIN domain - - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN GDHHQS3_k127_6773197_14 91464.S7335_179 4.218e-20 91.0 COG4691@1|root,COG4691@2|Bacteria,1G9I8@1117|Cyanobacteria 1117|Cyanobacteria S Plasmid stability protein - - - - - - - - - - - - - GDHHQS3_k127_6787925_0 94122.Shewana3_2156 1.771e-237 749.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,2QANN@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM peptidase M2, peptidyl-dipeptidase A - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 GDHHQS3_k127_6787925_3 1341151.ASZU01000009_gene908 3.712e-127 423.0 COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,4HC8W@91061|Bacilli,27C2A@186824|Thermoactinomycetaceae 91061|Bacilli E Pyridoxal-dependent decarboxylase conserved domain sidD - 4.1.1.86 ko:K13745 ko00260,ko01120,map00260,map01120 - R07650 RC00299 ko00000,ko00001,ko01000 - - - Pyridoxal_deC GDHHQS3_k127_6787925_4 204669.Acid345_1679 2.253e-111 376.0 COG0531@1|root,COG0531@2|Bacteria,3Y6AZ@57723|Acidobacteria,2JME9@204432|Acidobacteriia 204432|Acidobacteriia E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GDHHQS3_k127_6787925_2 342949.PNA2_1572 6.516e-149 481.0 COG0520@1|root,arCOG00065@2157|Archaea,2XVQU@28890|Euryarchaeota,243RH@183968|Thermococci 2157|Archaea E Cys/Met metabolism PLP-dependent enzyme - - 3.7.1.3,4.1.2.48 ko:K01556,ko:K01620 ko00260,ko00380,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00380,map01100,map01110,map01120,map01130,map01230 M00038 R00751,R00987,R02668,R03936,R06171 RC00284,RC00312,RC00372,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,Beta_elim_lyase GDHHQS3_k127_6787925_1 518766.Rmar_1948 1.818e-230 721.0 COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1FJ19@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Beta-eliminating lyase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GDHHQS3_k127_6788475_7 1121374.KB891589_gene45 1.765e-18 88.0 COG0733@1|root,COG0733@2|Bacteria,1NQUA@1224|Proteobacteria,1SN07@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - - - - - - - - - - SNF GDHHQS3_k127_6788475_4 565045.NOR51B_3 9.971e-114 379.0 COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,1JA4W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 GDHHQS3_k127_6788475_2 1121374.KB891589_gene44 2.332e-151 508.0 COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,1SM3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_6788475_5 204669.Acid345_1679 5.224e-113 378.0 COG0531@1|root,COG0531@2|Bacteria,3Y6AZ@57723|Acidobacteria,2JME9@204432|Acidobacteriia 204432|Acidobacteriia E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GDHHQS3_k127_6788475_3 342949.PNA2_1572 4.147e-144 468.0 COG0520@1|root,arCOG00065@2157|Archaea,2XVQU@28890|Euryarchaeota,243RH@183968|Thermococci 2157|Archaea E Cys/Met metabolism PLP-dependent enzyme - - 3.7.1.3,4.1.2.48 ko:K01556,ko:K01620 ko00260,ko00380,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00380,map01100,map01110,map01120,map01130,map01230 M00038 R00751,R00987,R02668,R03936,R06171 RC00284,RC00312,RC00372,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,Beta_elim_lyase GDHHQS3_k127_6788475_0 518766.Rmar_1948 6.072e-229 716.0 COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1FJ19@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Beta-eliminating lyase tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GDHHQS3_k127_6788475_1 1265313.HRUBRA_02104 1.891e-169 542.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1RWA9@1236|Gammaproteobacteria,1J6XV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 GDHHQS3_k127_6788475_6 225937.HP15_4020 2.179e-21 95.0 COG3103@1|root,COG3103@2|Bacteria,1QXFZ@1224|Proteobacteria,1RPAR@1236|Gammaproteobacteria,465YC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Sh3 type 3 domain protein - - - - - - - - - - - - DUF1302 GDHHQS3_k127_6805209_1 566466.NOR53_2349 1.275e-97 323.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1J4CY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GDHHQS3_k127_6805209_2 1121937.AUHJ01000003_gene3328 9.222e-71 249.0 COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,466K9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Carbon-nitrogen hydrolase yafV GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase GDHHQS3_k127_6805209_0 1123368.AUIS01000019_gene1224 2.937e-139 465.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R3QQ@1224|Proteobacteria,1RPFS@1236|Gammaproteobacteria,2NC05@225057|Acidithiobacillales 225057|Acidithiobacillales P Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N GDHHQS3_k127_6805209_3 1249627.D779_1945 2.843e-43 160.0 2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,1S7UG@1236|Gammaproteobacteria,1WY6X@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - GDHHQS3_k127_6812201_5 566466.NOR53_2754 8.282e-09 57.0 COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria,1J8GU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - NAD_binding_8 GDHHQS3_k127_6812201_0 1163617.SCD_n01513 2.374e-102 347.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria 28216|Betaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 GDHHQS3_k127_6812201_1 1163617.SCD_n01514 1.062e-76 264.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria 28216|Betaproteobacteria Q Abc transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran GDHHQS3_k127_6812201_2 748247.AZKH_p0369 1.072e-64 234.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,2KWAS@206389|Rhodocyclales 28216|Betaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD GDHHQS3_k127_6812201_4 472759.Nhal_0466 1.17e-25 117.0 COG3218@1|root,COG3218@2|Bacteria,1NCG2@1224|Proteobacteria,1T8NM@1236|Gammaproteobacteria,1X1B3@135613|Chromatiales 135613|Chromatiales S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux GDHHQS3_k127_6812201_3 1122604.JONR01000015_gene186 3.815e-50 184.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X42D@135614|Xanthomonadales 135614|Xanthomonadales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - - - - - - - - - - ApbE GDHHQS3_k127_6833721_12 324925.Ppha_0411 5.218e-40 155.0 2B73M@1|root,3204M@2|Bacteria 2|Bacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_21,Methyltransf_22 GDHHQS3_k127_6833721_5 485918.Cpin_4936 3.487e-107 357.0 COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IX1T@117747|Sphingobacteriia 976|Bacteroidetes S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans GDHHQS3_k127_6833721_11 1278309.KB907106_gene1284 7.73e-44 166.0 COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S764@1236|Gammaproteobacteria,1XREF@135619|Oceanospirillales 135619|Oceanospirillales E ACT domain - - - - - - - - - - - - ACT_6 GDHHQS3_k127_6833721_8 1415778.JQMM01000001_gene1077 1.984e-55 200.0 COG1309@1|root,COG1309@2|Bacteria,1RE2I@1224|Proteobacteria,1SH5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N GDHHQS3_k127_6833721_0 1266909.AUAG01000035_gene1151 2.39e-266 830.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales 135613|Chromatiales P PUA-like domain - - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 GDHHQS3_k127_6833721_1 498211.CJA_2895 1.22e-130 429.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1FFX3@10|Cellvibrio 1236|Gammaproteobacteria E Aminotransferase class I and II phhC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_6833721_3 396588.Tgr7_2936 8.172e-120 402.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM GDHHQS3_k127_6833721_4 713586.KB900536_gene1727 2.143e-110 366.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales 135613|Chromatiales HJ TIGRFAM alpha-L-glutamate ligase-like protein - - - - - - - - - - - - ATPgrasp_ST GDHHQS3_k127_6833721_6 1396858.Q666_08910 4.156e-102 341.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - ko:K13292 - - - - ko00000,ko01000 - - - LGT GDHHQS3_k127_6833721_2 1328313.DS2_17337 3.186e-128 417.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt GDHHQS3_k127_6833721_9 237609.PSAKL28_02330 3.244e-47 174.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 ko:K00287,ko:K18590 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020 DHFR_1 GDHHQS3_k127_6833721_7 935567.JAES01000006_gene357 3.639e-77 266.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1X3SY@135614|Xanthomonadales 135614|Xanthomonadales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos GDHHQS3_k127_6833721_13 159087.Daro_3484 6.364e-35 137.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,2KWM4@206389|Rhodocyclales 206389|Rhodocyclales P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 GDHHQS3_k127_6833721_10 95619.PM1_0200200 4.125e-45 167.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD GDHHQS3_k127_6833919_2 519989.ECTPHS_10666 7.326e-74 256.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales 135613|Chromatiales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD GDHHQS3_k127_6833919_1 1415778.JQMM01000001_gene1585 9.492e-81 279.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1J54Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GDHHQS3_k127_6833919_0 2340.JV46_04770 1.23e-224 721.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1J4XZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 GDHHQS3_k127_6863542_0 349521.HCH_04995 1.239e-224 704.0 COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales 135619|Oceanospirillales M dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - - - - - - - - - - NAD_binding_4,adh_short GDHHQS3_k127_6863542_3 319225.Plut_0230 5.414e-38 148.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3,AhpC-TSA GDHHQS3_k127_6863542_4 1046724.KB889828_gene2981 4.594e-16 82.0 2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,1SH79@1236|Gammaproteobacteria,46CBD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - - - - - - - - - - PHA_gran_rgn GDHHQS3_k127_6863542_5 637905.SVI_2391 0.0009326 51.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,2Q902@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM AsmA family protein asmA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 GDHHQS3_k127_6863542_1 84531.JMTZ01000022_gene4194 9.436e-135 440.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales 135614|Xanthomonadales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT GDHHQS3_k127_6863542_2 1123073.KB899244_gene271 6.964e-130 428.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1X36A@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase GDHHQS3_k127_6864695_1 565045.NOR51B_2110 1.016e-55 204.0 COG4773@1|root,COG4773@2|Bacteria 2|Bacteria P Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_6864695_2 1125863.JAFN01000001_gene1202 6.527e-29 122.0 COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,42U19@68525|delta/epsilon subdivisions,2WR05@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q PFAM thioesterase superfamily - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT GDHHQS3_k127_6864695_0 565045.NOR51B_2808 4.834e-261 820.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C indolepyruvate ferredoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C GDHHQS3_k127_6886228_7 380358.XALC_2423 1.777e-21 101.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales 135614|Xanthomonadales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N GDHHQS3_k127_6886228_8 767434.Fraau_2871 1.288e-12 78.0 COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,1S72T@1236|Gammaproteobacteria,1X3C2@135614|Xanthomonadales 135614|Xanthomonadales M Membrane protein TolA tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 GDHHQS3_k127_6886228_5 754476.Q7A_8 3.638e-40 153.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,46135@72273|Thiotrichales 72273|Thiotrichales U Biopolymer transport protein ExbD TolR tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD GDHHQS3_k127_6886228_2 1198232.CYCME_2169 5.846e-78 266.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,460DQ@72273|Thiotrichales 72273|Thiotrichales U MotA TolQ ExbB proton channel - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB GDHHQS3_k127_6886228_6 631362.Thi970DRAFT_03566 1.601e-28 119.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1WYUJ@135613|Chromatiales 135613|Chromatiales S Tol-Pal system-associated acyl-CoA thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 GDHHQS3_k127_6886228_0 913325.N799_03360 6.186e-161 512.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1X2XF@135614|Xanthomonadales 135614|Xanthomonadales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N GDHHQS3_k127_6886228_3 1163407.UU7_11457 6.602e-63 223.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1X373@135614|Xanthomonadales 135614|Xanthomonadales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N GDHHQS3_k127_6886228_4 1121937.AUHJ01000007_gene1902 2.513e-50 183.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC GDHHQS3_k127_6886228_1 396588.Tgr7_2237 1.102e-97 325.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1WX1Y@135613|Chromatiales 135613|Chromatiales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg GDHHQS3_k127_6889932_1 640081.Dsui_1519 1.201e-30 124.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,2KVM3@206389|Rhodocyclales 206389|Rhodocyclales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GDHHQS3_k127_6889932_0 1158146.KB907122_gene262 1.41e-61 219.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1WY1C@135613|Chromatiales 135613|Chromatiales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N GDHHQS3_k127_6889932_2 1049564.TevJSym_af00870 6.706e-11 70.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T3YZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 GDHHQS3_k127_689960_2 370438.PTH_0205 1.236e-41 158.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,2629P@186807|Peptococcaceae 186801|Clostridia H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - FolB,HPPK GDHHQS3_k127_689960_0 1163409.UUA_17500 1.297e-120 400.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1X3TM@135614|Xanthomonadales 135614|Xanthomonadales H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C GDHHQS3_k127_689960_1 1211114.ALIP01000113_gene878 3.192e-57 200.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X6V9@135614|Xanthomonadales 135614|Xanthomonadales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions VM57_07835 - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 GDHHQS3_k127_689960_4 105559.Nwat_0611 3.993e-07 59.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,1WXBS@135613|Chromatiales 135613|Chromatiales M NlpB/DapX lipoprotein - - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 GDHHQS3_k127_689960_3 1123073.KB899241_gene1863 4.15e-34 135.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1X41F@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_6901558_2 1122603.ATVI01000007_gene1439 7.63e-07 55.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X462@135614|Xanthomonadales 135614|Xanthomonadales M Male sterility protein - - - - - - - - - - - - Epimerase GDHHQS3_k127_6901558_0 1163407.UU7_15640 2.958e-115 386.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1X57H@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE GDHHQS3_k127_6901558_1 1205680.CAKO01000002_gene2852 9.785e-112 366.0 COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2TWRY@28211|Alphaproteobacteria,2JYTX@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 GDHHQS3_k127_6915522_0 1380391.JIAS01000011_gene4836 1.24e-152 488.0 COG3938@1|root,COG3938@2|Bacteria,1NVF9@1224|Proteobacteria,2TX8Z@28211|Alphaproteobacteria,2JR5Z@204441|Rhodospirillales 204441|Rhodospirillales E Proline racemase - - 5.1.1.8 ko:K12658 ko00330,map00330 - R03296 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase GDHHQS3_k127_6915522_1 1380394.JADL01000023_gene60 5.381e-94 322.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2JPPT@204441|Rhodospirillales 204441|Rhodospirillales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO GDHHQS3_k127_6915522_3 1437448.AZRT01000002_gene2270 3.54e-38 152.0 COG1802@1|root,COG1802@2|Bacteria,1RKMP@1224|Proteobacteria,2UAUH@28211|Alphaproteobacteria,1J2HU@118882|Brucellaceae 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR GDHHQS3_k127_6915522_2 761193.Runsl_0789 2.612e-93 314.0 COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,47MUZ@768503|Cytophagia 976|Bacteroidetes EM Belongs to the DapA family - - 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_6915522_6 1163408.UU9_04984 1.128e-12 78.0 COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales 135614|Xanthomonadales S Putative adhesin - - - - - - - - - - - - DUF4097 GDHHQS3_k127_6915522_5 84531.JMTZ01000009_gene3244 5.109e-26 110.0 COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales 135614|Xanthomonadales S protein, YerC YecD - - - - - - - - - - - - Trp_repressor GDHHQS3_k127_6915522_4 1500890.JQNL01000001_gene3223 8.977e-37 143.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1X4SF@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C GDHHQS3_k127_6917761_2 506534.Rhein_1765 1.094e-39 150.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,1X2RZ@135613|Chromatiales 135613|Chromatiales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_6917761_0 247634.GPB2148_2037 3.843e-135 445.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J8WE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_6917761_1 1265313.HRUBRA_02232 5.247e-91 316.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1J5HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT GDHHQS3_k127_6937726_0 1415779.JOMH01000001_gene494 3.908e-134 434.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1X33N@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C GDHHQS3_k127_6937726_3 1123256.KB907941_gene125 1.367e-42 162.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,1X7J3@135614|Xanthomonadales 135614|Xanthomonadales S PFAM DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX GDHHQS3_k127_6937726_2 1123261.AXDW01000009_gene166 1.153e-70 244.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,1X6B8@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 GDHHQS3_k127_6937726_1 1123261.AXDW01000009_gene167 4.743e-120 392.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1X54Q@135614|Xanthomonadales 135614|Xanthomonadales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate GDHHQS3_k127_6953900_4 522306.CAP2UW1_1752 2.307e-65 224.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran GDHHQS3_k127_6953900_5 323850.Shew_1935 5.723e-60 230.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,2QATA@267890|Shewanellaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 GDHHQS3_k127_6953900_3 552811.Dehly_1596 7.973e-101 337.0 COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,34DQK@301297|Dehalococcoidia 2|Bacteria E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 ko:K12339,ko:K21148 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122 M00021 R00897,R03132,R03601,R04859,R10610 RC00020,RC02814,RC02821,RC02876,RC03225 ko00000,ko00001,ko00002,ko01000 - - - PALP GDHHQS3_k127_6953900_2 1123253.AUBD01000010_gene2149 6.077e-140 464.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1X32P@135614|Xanthomonadales 135614|Xanthomonadales E aminotransferase - - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GDHHQS3_k127_6953900_6 1056820.KB900642_gene407 2.083e-49 190.0 COG1305@1|root,COG3063@1|root,COG1305@2|Bacteria,COG3063@2|Bacteria,1QZGT@1224|Proteobacteria,1T46B@1236|Gammaproteobacteria,2PNS8@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria ENU Transglutaminase-like superfamily - - - - - - - - - - - - TPR_19,TPR_8,Transglut_core GDHHQS3_k127_6953900_0 1117647.M5M_03535 9.045e-184 581.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RNB1@1236|Gammaproteobacteria,1J4UW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 GDHHQS3_k127_6953900_1 1415778.JQMM01000001_gene610 3.331e-163 522.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1J5JA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT GDHHQS3_k127_6953900_7 1408164.MOLA814_00485 0.0009165 42.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria 28216|Betaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran GDHHQS3_k127_6962460_4 1385517.N800_14305 1.83e-100 339.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X5BS@135614|Xanthomonadales 135614|Xanthomonadales M heptosyltransferase opsX - - ko:K12982 - - - - ko00000,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 GDHHQS3_k127_6962460_1 382245.ASA_3795 2.247e-146 474.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1Y3Q7@135624|Aeromonadales 135624|Aeromonadales E Cys/Met metabolism PLP-dependent enzyme metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GDHHQS3_k127_6962460_12 1479237.JMLY01000001_gene1231 1.814e-43 162.0 COG0859@1|root,COG0859@2|Bacteria,1MZGQ@1224|Proteobacteria,1S7TT@1236|Gammaproteobacteria,46AYD@72275|Alteromonadaceae 1236|Gammaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - - GDHHQS3_k127_6962460_7 323261.Noc_1391 2.552e-82 283.0 COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria,1SDAB@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Phytanoyl-CoA dioxygenase (PhyH) - - 1.14.11.46 ko:K21195 ko00440,map00440 - R10724 RC01107 ko00000,ko00001,ko01000 - - - PhyH GDHHQS3_k127_6962460_15 663321.REG_1083 1.254e-34 149.0 COG0706@1|root,COG0706@2|Bacteria,1P1HH@1224|Proteobacteria 1224|Proteobacteria U 60Kd inner membrane protein - - - - - - - - - - - - 60KD_IMP GDHHQS3_k127_6962460_6 1121939.L861_15145 2.352e-96 340.0 COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XIUH@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase of alkaline phosphatase superfamily - - - ko:K07014 - - - - ko00000 - - - DUF3413,Sulfatase GDHHQS3_k127_6962460_10 436308.Nmar_0664 1.161e-65 240.0 COG1887@1|root,arCOG04827@2157|Archaea 2157|Archaea M CDP-glycerol poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf GDHHQS3_k127_6962460_22 1230343.CANP01000046_gene3646 3.292e-05 49.0 2AGY4@1|root,33HSC@2|Bacteria,1NJ83@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_6962460_3 398527.Bphyt_5997 5.308e-113 376.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VXMC@28216|Betaproteobacteria,1K0UT@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37 ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R04152 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_5 GDHHQS3_k127_6962460_19 349124.Hhal_2346 1.216e-27 120.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT GDHHQS3_k127_6962460_2 1122604.JONR01000008_gene2214 7.175e-126 414.0 COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1R6QP@1224|Proteobacteria,1RZWJ@1236|Gammaproteobacteria,1XA0A@135614|Xanthomonadales 135614|Xanthomonadales EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_N GDHHQS3_k127_6962460_0 472759.Nhal_1306 8.284e-223 702.0 COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RY5Q@1236|Gammaproteobacteria,1X09Q@135613|Chromatiales 135613|Chromatiales C Phosphoenolpyruvate phosphomutase - - 5.4.2.9 ko:K01841 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R00661 RC02792 ko00000,ko00001,ko01000 - - - NTP_transf_3,PEP_mutase GDHHQS3_k127_6962460_8 323261.Noc_1318 6.462e-80 275.0 COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,1S3HP@1236|Gammaproteobacteria,1WZBI@135613|Chromatiales 135613|Chromatiales M MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 GDHHQS3_k127_6962460_13 435908.IDSA_01375 4.336e-41 173.0 COG4967@1|root,COG4967@2|Bacteria,1R7RM@1224|Proteobacteria,1S1SU@1236|Gammaproteobacteria,2QGRF@267893|Idiomarinaceae 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_6962460_17 292415.Tbd_1862 9.017e-30 136.0 COG4726@1|root,COG4726@2|Bacteria,1RCDE@1224|Proteobacteria 1224|Proteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - PilX_N GDHHQS3_k127_6962460_20 1232683.ADIMK_0980 7.392e-07 59.0 COG4795@1|root,COG4795@2|Bacteria,1RHSZ@1224|Proteobacteria,1S374@1236|Gammaproteobacteria,468S3@72275|Alteromonadaceae 1236|Gammaproteobacteria U prepilin peptidase dependent protein ppdB - - ko:K02680 - - - - ko00000,ko02044 - - - N_methyl GDHHQS3_k127_6962460_21 666681.M301_2620 1.146e-06 58.0 COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl GDHHQS3_k127_6962460_18 765910.MARPU_08935 1.524e-29 129.0 COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WW8P@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg GDHHQS3_k127_6962460_5 983917.RGE_39420 3.629e-98 356.0 COG0784@1|root,COG2202@1|root,COG4251@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,2WHTA@28216|Betaproteobacteria 28216|Betaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg GDHHQS3_k127_6962460_9 751944.HALDL1_15195 4.148e-74 278.0 COG0642@1|root,arCOG02329@1|root,arCOG02350@1|root,arCOG02352@1|root,arCOG02329@2157|Archaea,arCOG02350@2157|Archaea,arCOG02352@2157|Archaea,arCOG02358@2157|Archaea,2Y5ZU@28890|Euryarchaeota 28890|Euryarchaeota T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9 GDHHQS3_k127_6962460_16 903818.KI912268_gene3359 2.038e-34 148.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,3Y8F2@57723|Acidobacteria 57723|Acidobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg GDHHQS3_k127_6962460_14 546414.Deide_01860 6.388e-36 145.0 COG0784@1|root,COG0784@2|Bacteria,1WMM2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T PFAM response regulator receiver - - - - - - - - - - - - Response_reg GDHHQS3_k127_6962460_11 204669.Acid345_4067 1.07e-57 207.0 COG2197@1|root,COG2197@2|Bacteria,3Y7QM@57723|Acidobacteria,2JMPR@204432|Acidobacteriia 204432|Acidobacteriia T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GDHHQS3_k127_6972181_1 1249627.D779_2908 1.113e-47 173.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,1WWZ7@135613|Chromatiales 135613|Chromatiales O PFAM peptidase - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 GDHHQS3_k127_6972181_2 66269.NL54_07400 1.209e-29 128.0 COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,1RMJD@1236|Gammaproteobacteria,3W0MF@53335|Pantoea 1236|Gammaproteobacteria I lipid carrier protein yhbT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - SCP2 GDHHQS3_k127_6972181_0 305700.B447_07754 5.399e-199 623.0 COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,2VH5G@28216|Betaproteobacteria,2KXZ2@206389|Rhodocyclales 206389|Rhodocyclales S Fic/DOC family - - - - - - - - - - - - Fic GDHHQS3_k127_6976893_3 1348338.ADILRU_2300 4.57e-06 57.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - DUF4347,Haemagg_act,PATR GDHHQS3_k127_6976893_2 1396141.BATP01000020_gene2 3.916e-09 66.0 COG2755@1|root,COG3317@1|root,COG4409@1|root,COG5267@1|root,COG2755@2|Bacteria,COG3317@2|Bacteria,COG4409@2|Bacteria,COG5267@2|Bacteria,46XM5@74201|Verrucomicrobia,2IW6D@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Carbohydrate esterase, sialic acid-specific acetylesterase - - - - - - - - - - - - Lipase_GDSL_2,SASA GDHHQS3_k127_6976893_0 1116472.MGMO_137c00120 3.707e-41 156.0 2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria,1XGHH@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - GDHHQS3_k127_6976893_1 301.JNHE01000002_gene2367 7.961e-13 68.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1YH64@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT GDHHQS3_k127_6995541_1 1049564.TevJSym_be00030 1.207e-102 341.0 COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1J5V7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Peptidase family U32 yhbV - - - - - - - - - - - Peptidase_U32 GDHHQS3_k127_6995541_0 1255043.TVNIR_3824 4.742e-167 539.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1WWBG@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD GDHHQS3_k127_6997086_0 1449357.JQLK01000001_gene2118 3.729e-31 138.0 COG3385@1|root,COG3385@2|Bacteria,1WI7I@1297|Deinococcus-Thermus 2|Bacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 GDHHQS3_k127_7016906_2 565045.NOR51B_1505 8.821e-142 459.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1J99F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Aminotransferase class I and II aspC - 2.6.1.1,2.6.1.84,3.6.3.21 ko:K00812,ko:K02028,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00236 R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko00002,ko01000,ko01007,ko02000 3.A.1.3 - - ABC_tran,Aminotran_1_2 GDHHQS3_k127_7016906_6 6500.XP_005092325.1 1.726e-73 259.0 COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria 33208|Metazoa ET Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP GDHHQS3_k127_7016906_1 565045.NOR51B_2349 7.906e-181 577.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1J801@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C FAD linked oxidases, C-terminal domain - - 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 GDHHQS3_k127_7016906_0 314285.KT71_04350 3.769e-199 631.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 GDHHQS3_k127_7016906_4 391624.OIHEL45_20671 1.465e-129 445.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-transferase - - - - - - - - - - - - Acyl_transf_3 GDHHQS3_k127_7016906_3 1031711.RSPO_c00318 1.085e-141 460.0 COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2W362@28216|Betaproteobacteria,1JZMY@119060|Burkholderiaceae 28216|Betaproteobacteria E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 GDHHQS3_k127_7016906_5 102129.Lepto7375DRAFT_1521 8.502e-85 292.0 COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria 1117|Cyanobacteria E Threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GDHHQS3_k127_7016906_7 797304.Natgr_3053 1.195e-43 171.0 COG0384@1|root,arCOG02256@2157|Archaea,2XUVT@28890|Euryarchaeota,23RZN@183963|Halobacteria 183963|Halobacteria S Phenazine biosynthesis protein phzf family phzF - - - - - - - - - - - PhzC-PhzF GDHHQS3_k127_7016906_9 861299.J421_5888 2.543e-26 109.0 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 GDHHQS3_k127_7016906_8 861299.J421_5889 9.676e-27 115.0 2DSP1@1|root,33GVU@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 GDHHQS3_k127_7034333_1 1255043.TVNIR_2774 3.809e-57 201.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1WW24@135613|Chromatiales 135613|Chromatiales OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease GDHHQS3_k127_7034333_0 1121013.P873_06920 3.35e-81 283.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1X4P4@135614|Xanthomonadales 135614|Xanthomonadales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N GDHHQS3_k127_7050159_2 1121033.AUCF01000006_gene4262 6.793e-178 564.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2JQTH@204441|Rhodospirillales 204441|Rhodospirillales S protein conserved in bacteria - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE GDHHQS3_k127_7050159_14 338969.Rfer_0248 2.311e-05 52.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2WC2E@28216|Betaproteobacteria,4AIRV@80864|Comamonadaceae 28216|Betaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - GDHHQS3_k127_7050159_7 663610.JQKO01000012_gene3076 1.767e-75 268.0 COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_7050159_8 1123368.AUIS01000019_gene1213 4.716e-69 237.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales 225057|Acidithiobacillales C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 GDHHQS3_k127_7050159_0 1168065.DOK_09459 1.246e-214 688.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1J5AB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.3.99.16 ko:K00256,ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_7050159_6 1230476.C207_01213 1.534e-85 296.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 GDHHQS3_k127_7050159_9 211165.AJLN01000039_gene1896 1.517e-56 208.0 COG0385@1|root,COG0385@2|Bacteria,1G2W8@1117|Cyanobacteria,1JJ6Q@1189|Stigonemataceae 1117|Cyanobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF GDHHQS3_k127_7050159_4 543728.Vapar_5311 3.392e-109 363.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VP80@28216|Betaproteobacteria,4ADEX@80864|Comamonadaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 GDHHQS3_k127_7050159_10 1144275.COCOR_00870 6.939e-36 141.0 COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria 1224|Proteobacteria J Translation initiation inhibitor, yjgF family - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP GDHHQS3_k127_7050159_3 566466.NOR53_1510 3.276e-134 457.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RS91@1236|Gammaproteobacteria,1J4WX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_7050159_1 1230476.C207_02619 5.516e-186 601.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6,4.1.1.7 ko:K01576,ko:K01652 ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00595,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_7050159_13 392499.Swit_1527 9.939e-17 84.0 COG2010@1|root,COG2010@2|Bacteria,1NK3D@1224|Proteobacteria,2UN55@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 GDHHQS3_k127_7050159_5 686340.Metal_1984 3.283e-93 312.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T23Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA GDHHQS3_k127_7050159_12 379066.GAU_3813 1.277e-17 84.0 COG2271@1|root,COG2271@2|Bacteria,1ZSWA@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GDHHQS3_k127_7068673_3 190486.XAC3385 1.05e-56 203.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 GDHHQS3_k127_7068673_0 754477.Q7C_1790 8.558e-250 795.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales 72273|Thiotrichales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase GDHHQS3_k127_7068673_4 1260251.SPISAL_01405 3.456e-41 161.0 COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,1T424@1236|Gammaproteobacteria,1X2QN@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - GDHHQS3_k127_7068673_1 1198232.CYCME_0053 2.639e-189 601.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales 72273|Thiotrichales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt GDHHQS3_k127_7068673_5 1121013.P873_11365 1.075e-34 140.0 COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X7FM@135614|Xanthomonadales 135614|Xanthomonadales J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 GDHHQS3_k127_7068673_2 713586.KB900536_gene1770 1.299e-108 360.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales 135613|Chromatiales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM GDHHQS3_k127_7098109_2 748247.AZKH_0434 6.485e-78 265.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,2KZSM@206389|Rhodocyclales 206389|Rhodocyclales H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 GDHHQS3_k127_7098109_4 318167.Sfri_3025 1.645e-26 118.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1S1VT@1236|Gammaproteobacteria,2QAAI@267890|Shewanellaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp GDHHQS3_k127_7098109_0 426114.THI_0200 3.284e-179 571.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VJHJ@28216|Betaproteobacteria,1KJKE@119065|unclassified Burkholderiales 28216|Betaproteobacteria E glutamine synthetase puuA2 - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C GDHHQS3_k127_7098109_1 574966.KB898648_gene789 1.838e-115 382.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1XHZF@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase GDHHQS3_k127_7098109_3 1123366.TH3_05685 1.268e-59 211.0 COG1396@1|root,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,2TU8R@28211|Alphaproteobacteria,2JSB1@204441|Rhodospirillales 204441|Rhodospirillales K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 GDHHQS3_k127_7098109_5 1089553.Tph_c01950 0.0009726 42.0 28VBQ@1|root,2ZHEF@2|Bacteria,1W5WF@1239|Firmicutes,257CF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - GDHHQS3_k127_7133298_3 1121935.AQXX01000104_gene353 2.809e-18 87.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1XHTW@135619|Oceanospirillales 135619|Oceanospirillales EF Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N GDHHQS3_k127_7133298_0 1046724.KB889902_gene3241 1.705e-168 534.0 COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria,46A9X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Virulence protein RhuM family - - - - - - - - - - - - Fic,Virulence_RhuM GDHHQS3_k127_7133298_1 1523503.JPMY01000009_gene671 4.689e-55 199.0 COG1695@1|root,COG1695@2|Bacteria,1RFWJ@1224|Proteobacteria,1SYA4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Virulence activator alpha C-term - - - ko:K10917 ko02024,ko05111,map02024,map05111 - - - ko00000,ko00001,ko03000 - - - PadR,Vir_act_alpha_C GDHHQS3_k127_7133298_2 349521.HCH_01940 2.068e-37 142.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1XI9F@135619|Oceanospirillales 135619|Oceanospirillales Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 GDHHQS3_k127_714893_6 1415780.JPOG01000001_gene2437 2.673e-88 305.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X32B@135614|Xanthomonadales 135614|Xanthomonadales P COG2217 Cation transport ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase GDHHQS3_k127_714893_12 426114.THI_1359 6.779e-10 64.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria 28216|Betaproteobacteria S FixH - - - ko:K09926 - - - - ko00000 - - - FixH GDHHQS3_k127_714893_2 713587.THITH_06425 4.437e-174 557.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C GDHHQS3_k127_714893_16 1300345.LF41_2203 1.182e-05 53.0 2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria,1X7EB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_714893_4 1123073.KB899241_gene3484 1.248e-95 321.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1X4SS@135614|Xanthomonadales 135614|Xanthomonadales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N GDHHQS3_k127_714893_15 583345.Mmol_0543 7.13e-07 53.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ GDHHQS3_k127_714893_5 1123377.AUIV01000005_gene1734 7.116e-92 305.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1X3EF@135614|Xanthomonadales 135614|Xanthomonadales C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO GDHHQS3_k127_714893_1 1123073.KB899241_gene3481 3.451e-260 806.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1X3WE@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 GDHHQS3_k127_714893_11 1408164.MOLA814_00052 3.785e-18 89.0 2E69Z@1|root,330XW@2|Bacteria,1MZGG@1224|Proteobacteria,2VW79@28216|Betaproteobacteria 28216|Betaproteobacteria C Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria hip - - - - - - - - - - - HIPIP GDHHQS3_k127_714893_13 477228.YO5_12832 1.659e-09 64.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1Z190@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat GDHHQS3_k127_714893_8 1121374.KB891587_gene3036 6.863e-52 190.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K response regulator - - - - - - - - - - - - GerE,Response_reg GDHHQS3_k127_714893_7 1120792.JAFV01000001_gene2158 2.652e-77 278.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,36Y0R@31993|Methylocystaceae 28211|Alphaproteobacteria T PAS fold fixL - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_9 GDHHQS3_k127_714893_14 1123377.AUIV01000001_gene901 2.63e-09 61.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1X883@135614|Xanthomonadales 135614|Xanthomonadales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 GDHHQS3_k127_714893_3 913325.N799_00505 3.492e-145 462.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1X3D9@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17 GDHHQS3_k127_714893_0 1234364.AMSF01000016_gene1685 1.085e-311 962.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1X4JC@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C GDHHQS3_k127_714893_10 1163407.UU7_10401 1.017e-23 110.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,1SAC6@1236|Gammaproteobacteria,1X7KQ@135614|Xanthomonadales 135614|Xanthomonadales C succinate dehydrogenase sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt GDHHQS3_k127_714893_9 1123237.Salmuc_04790 1.044e-31 127.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt GDHHQS3_k127_7151692_7 1380408.AVGH01000022_gene1928 1.587e-05 49.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,21VC1@150247|Anoxybacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase GDHHQS3_k127_7151692_6 153948.NAL212_2555 8.382e-11 65.0 2DRB5@1|root,33B20@2|Bacteria,1PVK8@1224|Proteobacteria,2VYTH@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox GDHHQS3_k127_7151692_5 1100721.ALKO01000032_gene173 3.471e-18 87.0 COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria 28216|Betaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_7151692_3 1123392.AQWL01000009_gene1085 5.109e-22 99.0 COG4118@1|root,COG4118@2|Bacteria 2|Bacteria D positive regulation of growth - - - - - - - - - - - - PhdYeFM_antitox GDHHQS3_k127_7151692_2 713587.THITH_03375 1.319e-25 109.0 2AFGR@1|root,315H2@2|Bacteria,1PVK9@1224|Proteobacteria,1STVA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox GDHHQS3_k127_7151692_4 864051.BurJ1DRAFT_1943 2.104e-21 96.0 COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria 28216|Betaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin GDHHQS3_k127_7151692_8 83406.HDN1F_36290 1.818e-05 50.0 COG3668@1|root,COG3668@2|Bacteria,1N75M@1224|Proteobacteria,1S67C@1236|Gammaproteobacteria,1JBBB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the RelE toxin family - - - ko:K19092 - - - - ko00000,ko02048 - - - ParE_toxin GDHHQS3_k127_7151692_0 1487953.JMKF01000041_gene3114 4.907e-157 511.0 COG0212@1|root,COG0212@2|Bacteria,1G2B2@1117|Cyanobacteria,1H86T@1150|Oscillatoriales 1117|Cyanobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - - - - - - - - - - - GDHHQS3_k127_7151692_1 713586.KB900536_gene403 1.039e-77 266.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1SYH1@1236|Gammaproteobacteria,1X2II@135613|Chromatiales 135613|Chromatiales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 GDHHQS3_k127_7165867_4 189753.AXAS01000016_gene1404 6.559e-49 181.0 COG1845@1|root,COG1845@2|Bacteria,1MXAB@1224|Proteobacteria,2TRFQ@28211|Alphaproteobacteria,3JTBK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c oxidase subunit III coxO - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 GDHHQS3_k127_7165867_1 1535422.ND16A_1083 1.448e-304 941.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RNUX@1236|Gammaproteobacteria,2Q7YB@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 GDHHQS3_k127_7165867_2 1535422.ND16A_1084 7.026e-169 541.0 COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria,2Q7HW@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome C oxidase subunit II, periplasmic domain - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C GDHHQS3_k127_7165867_3 1116472.MGMO_71c00030 2.406e-55 201.0 2E0NX@1|root,32W7W@2|Bacteria,1N3K6@1224|Proteobacteria,1SA9T@1236|Gammaproteobacteria,1XFTJ@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - GDHHQS3_k127_7165867_5 1121937.AUHJ01000001_gene573 2.487e-36 148.0 2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria,1S7CH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 GDHHQS3_k127_7165867_0 1120953.AUBH01000005_gene2427 0.0 1294.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,46979@72275|Alteromonadaceae 1236|Gammaproteobacteria G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 GDHHQS3_k127_7185289_2 1123073.KB899242_gene1199 3.639e-65 225.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales 135614|Xanthomonadales E Acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_7185289_1 1288826.MSNKSG1_14177 6.68e-75 263.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA GDHHQS3_k127_7185289_0 1279017.AQYJ01000027_gene1618 4.996e-164 523.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,4674P@72275|Alteromonadaceae 1236|Gammaproteobacteria EU Prolyl oligopeptidase, N-terminal beta-propeller domain - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N GDHHQS3_k127_7190258_1 247634.GPB2148_547 2.465e-111 362.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria,1J8G4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14,6.4.1.6 ko:K01474,ko:K10854 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B GDHHQS3_k127_7190258_2 247633.GP2143_10507 6.297e-76 260.0 COG1335@1|root,COG1335@2|Bacteria,1MVZX@1224|Proteobacteria,1T012@1236|Gammaproteobacteria,1JA63@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase GDHHQS3_k127_7190258_5 1267005.KB911265_gene3648 4.118e-12 71.0 COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria 1224|Proteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding GDHHQS3_k127_7190258_3 329726.AM1_2994 1.452e-26 115.0 COG0664@1|root,COG0664@2|Bacteria,1G9GW@1117|Cyanobacteria 1117|Cyanobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding GDHHQS3_k127_7190258_0 566466.NOR53_2826 1.14e-174 559.0 COG0591@1|root,COG0591@2|Bacteria,1MVBV@1224|Proteobacteria,1RZ3Y@1236|Gammaproteobacteria,1J9ST@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF GDHHQS3_k127_7190258_4 247634.GPB2148_746 1.957e-14 73.0 COG0183@1|root,COG0183@2|Bacteria,1QE43@1224|Proteobacteria,1RZQI@1236|Gammaproteobacteria,1J5BQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Thiolase, C-terminal domain - - - - - - - - - - - - Thiolase_C,Thiolase_N GDHHQS3_k127_71999_1 314275.MADE_1010040 1.989e-105 354.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT GDHHQS3_k127_71999_3 365044.Pnap_1678 1.93e-76 265.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,4A9S4@80864|Comamonadaceae 28216|Betaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B GDHHQS3_k127_71999_10 1367847.JCM7686_2591 0.0004973 50.0 COG0500@1|root,COG2226@2|Bacteria,1R92P@1224|Proteobacteria,2VEX9@28211|Alphaproteobacteria,2PZ7K@265|Paracoccus 28211|Alphaproteobacteria Q Hypothetical methyltransferase - - - - - - - - - - - - Methyltransf_11 GDHHQS3_k127_71999_4 1528106.JRJE01000005_gene1349 3.026e-59 212.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2JS6U@204441|Rhodospirillales 204441|Rhodospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H GDHHQS3_k127_71999_2 740709.A10D4_06081 9.669e-86 291.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,2QFH0@267893|Idiomarinaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T GDHHQS3_k127_71999_0 1333856.L686_04220 2.474e-119 398.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1YZRR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT GDHHQS3_k127_71999_7 396595.TK90_0220 6.473e-18 91.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1WZ6E@135613|Chromatiales 135613|Chromatiales NU Type IV minor pilin ComP, DNA uptake sequence receptor - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl GDHHQS3_k127_71999_9 1217718.ALOU01000031_gene1574 2.044e-06 59.0 COG4970@1|root,COG4970@2|Bacteria,1N0DB@1224|Proteobacteria,2VU1S@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl GDHHQS3_k127_71999_8 1120953.AUBH01000012_gene375 1.603e-12 78.0 COG4795@1|root,COG4795@2|Bacteria,1RHSZ@1224|Proteobacteria,1S374@1236|Gammaproteobacteria,468S3@72275|Alteromonadaceae 1236|Gammaproteobacteria U prepilin peptidase dependent protein ppdB - - ko:K02680 - - - - ko00000,ko02044 - - - N_methyl GDHHQS3_k127_71999_6 1300345.LF41_656 2.549e-24 118.0 COG4726@1|root,COG4726@2|Bacteria 2|Bacteria NU Pilus assembly protein PilX - - - - - - - - - - - - PilX_N GDHHQS3_k127_71999_5 745411.B3C1_17162 4.802e-42 176.0 COG4967@1|root,COG4967@2|Bacteria,1R7RM@1224|Proteobacteria,1S1SU@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_7214105_2 1122134.KB893651_gene2330 4.375e-63 219.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XJJA@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA GDHHQS3_k127_7214105_0 1205753.A989_15852 7.558e-197 624.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1X3HE@135614|Xanthomonadales 135614|Xanthomonadales T Phosphate starvation protein PhoH - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH GDHHQS3_k127_7214105_5 2340.JV46_22000 7.302e-13 81.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1JA5D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X GDHHQS3_k127_7214105_3 316056.RPC_1443 1.655e-57 210.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,3JRSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin GDHHQS3_k127_7214105_8 558884.JRGM01000130_gene171 6.409e-05 51.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria,1Y53V@135624|Aeromonadales 135624|Aeromonadales C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh GDHHQS3_k127_7214105_4 349124.Hhal_1956 7.961e-34 134.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1WYFA@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC GDHHQS3_k127_7214105_7 1265313.HRUBRA_01982 3.901e-05 51.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1J7BW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the DsrF TusC family tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE GDHHQS3_k127_7214105_6 1278307.KB906972_gene1233 1.6e-08 65.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,2QI7E@267894|Psychromonadaceae 1236|Gammaproteobacteria P DsrE/DsrF-like family tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE GDHHQS3_k127_7214105_1 1122185.N792_05135 2.438e-88 314.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1X2ZN@135614|Xanthomonadales 135614|Xanthomonadales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_19 GDHHQS3_k127_7222296_5 1415755.JQLV01000002_gene576 1.036e-06 51.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XI3Q@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS GDHHQS3_k127_7222296_1 1411685.U062_00600 1.759e-122 404.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1J4IQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N GDHHQS3_k127_7222296_3 491952.Mar181_2591 7.92e-72 246.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XJ5T@135619|Oceanospirillales 135619|Oceanospirillales H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth GDHHQS3_k127_7222296_4 314287.GB2207_03609 1.675e-33 139.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1J8VC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 NTP_transf_3 GDHHQS3_k127_7222296_6 1120983.KB894570_gene1350 1.781e-05 51.0 2AD9M@1|root,312YS@2|Bacteria,1PUCH@1224|Proteobacteria,2VCXS@28211|Alphaproteobacteria,1JQJ3@119043|Rhodobiaceae 28211|Alphaproteobacteria S NADH-dependant formate dehydrogenase delta subunit FdsD - - - - - - - - - - - - FdsD GDHHQS3_k127_7222296_2 314287.GB2207_03649 5.924e-81 278.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1JBRV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ GDHHQS3_k127_7222296_0 339670.Bamb_0895 0.0 1450.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1JZNE@119060|Burkholderiaceae 28216|Betaproteobacteria C Formate dehydrogenase alpha subunit fdsA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 GDHHQS3_k127_7239662_1 713587.THITH_07425 6.285e-118 395.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1SMH6@1236|Gammaproteobacteria,1X0JB@135613|Chromatiales 135613|Chromatiales E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept GDHHQS3_k127_7239662_0 1121013.P873_12285 2.43e-143 462.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1X4QH@135614|Xanthomonadales 135614|Xanthomonadales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 GDHHQS3_k127_7239662_4 1123073.KB899241_gene2270 3.353e-46 171.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1X878@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB GDHHQS3_k127_7239662_5 1123073.KB899241_gene2269 1.452e-40 155.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1X6J5@135614|Xanthomonadales 135614|Xanthomonadales H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK1 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK GDHHQS3_k127_7239662_3 631362.Thi970DRAFT_03885 4.944e-78 267.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1WXHM@135613|Chromatiales 135613|Chromatiales IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 GDHHQS3_k127_7239662_2 713586.KB900536_gene2467 3.084e-109 366.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,1WWJG@135613|Chromatiales 135613|Chromatiales S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 GDHHQS3_k127_7239662_6 1286106.MPL1_12698 2.084e-29 117.0 COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,1SD4N@1236|Gammaproteobacteria,4636M@72273|Thiotrichales 72273|Thiotrichales K Bacterial antitoxin of type II TA system, VapB - - - - - - - - - - - - VapB_antitoxin GDHHQS3_k127_7239662_7 754476.Q7A_2745 1.595e-23 100.0 COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria,462PP@72273|Thiotrichales 72273|Thiotrichales S PIN domain - - - - - - - - - - - - PIN GDHHQS3_k127_7240433_5 85643.Tmz1t_2951 4.809e-31 122.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales 206389|Rhodocyclales E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D GDHHQS3_k127_7240433_0 258594.RPA0658 1.428e-224 704.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E benzoyl-CoA reductase - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D GDHHQS3_k127_7240433_1 1244869.H261_03128 1.429e-188 598.0 COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04114 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG GDHHQS3_k127_7240433_2 85643.Tmz1t_2948 1.572e-120 392.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales 206389|Rhodocyclales I BadF/BadG/BcrA/BcrD ATPase family - - 1.3.7.8 ko:K04115 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG GDHHQS3_k127_7240433_4 258594.RPA0662 3.62e-35 135.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2UG0Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria C ferredoxin - - - - - - - - - - - - Fer4 GDHHQS3_k127_7240433_3 391625.PPSIR1_18797 2.728e-57 203.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 GDHHQS3_k127_7249384_4 34007.IT40_16315 4.73e-22 96.0 COG0633@1|root,COG0633@2|Bacteria,1N261@1224|Proteobacteria,2UC7B@28211|Alphaproteobacteria,2PYTW@265|Paracoccus 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 GDHHQS3_k127_7249384_2 314285.KT71_06272 7.325e-88 305.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,1J9C0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GDHHQS3_k127_7249384_3 291985.CCSI01000007_gene460 2.701e-56 211.0 28M5H@1|root,2ZAJ9@2|Bacteria,1RJY2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7249384_1 326297.Sama_2949 1.931e-166 533.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,2Q9KH@267890|Shewanellaceae 1236|Gammaproteobacteria C D-isomer specific 2-hydroxyacid dehydrogenase catalytic region serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYL1228.KPN_03348 2-Hacid_dh,2-Hacid_dh_C,ACT GDHHQS3_k127_7249384_0 1500890.JQNL01000001_gene3106 1.748e-168 548.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1X4KB@135614|Xanthomonadales 135614|Xanthomonadales C FAD-linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 GDHHQS3_k127_7249384_5 1123073.KB899242_gene1634 3.307e-08 55.0 COG2835@1|root,COG2835@2|Bacteria,1P6IM@1224|Proteobacteria,1SV7D@1236|Gammaproteobacteria,1X7IE@135614|Xanthomonadales 135614|Xanthomonadales S Trm112p-like protein - - - - - - - - - - - - Trm112p GDHHQS3_k127_7274530_2 745411.B3C1_12174 6.433e-99 329.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1J4M2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT GDHHQS3_k127_7274530_3 572477.Alvin_2484 1.008e-52 192.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1WY0M@135613|Chromatiales 135613|Chromatiales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM GDHHQS3_k127_7274530_4 1121940.AUDZ01000009_gene2098 1.949e-32 128.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1XKJQ@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 GDHHQS3_k127_7274530_0 1384054.N790_05150 3.921e-126 419.0 COG3211@1|root,COG3211@2|Bacteria,1QY0R@1224|Proteobacteria,1S13A@1236|Gammaproteobacteria,1X5KR@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839,TAT_signal GDHHQS3_k127_7274530_1 1120970.AUBZ01000031_gene3138 3.149e-125 407.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB GDHHQS3_k127_7298399_2 1392540.P256_02117 4.21e-13 70.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,3NJMZ@468|Moraxellaceae 1236|Gammaproteobacteria E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 GDHHQS3_k127_7298399_0 713586.KB900536_gene2597 1.861e-99 341.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 GDHHQS3_k127_7298399_1 666685.R2APBS1_3248 5.037e-73 256.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1X3DS@135614|Xanthomonadales 135614|Xanthomonadales CH Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol visC - - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3,SE GDHHQS3_k127_7313151_2 234267.Acid_1726 1.998e-10 61.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria 2|Bacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_12 GDHHQS3_k127_7313151_0 886293.Sinac_4372 7.406e-162 522.0 COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes 203682|Planctomycetes M PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_4 GDHHQS3_k127_7313151_1 401526.TcarDRAFT_2300 1.541e-64 237.0 COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4H280@909932|Negativicutes 909932|Negativicutes I Short chain fatty acid transporter - - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans GDHHQS3_k127_7334843_3 768671.ThimaDRAFT_1059 3.843e-34 132.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1WYKM@135613|Chromatiales 135613|Chromatiales S RNA-binding protein - - - - - - - - - - - - RRM_1 GDHHQS3_k127_7334843_2 1284352.AOIG01000003_gene1154 1.131e-56 199.0 COG0346@1|root,COG0346@2|Bacteria,1V235@1239|Firmicutes,4HHQP@91061|Bacilli,26WSR@186822|Paenibacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase GDHHQS3_k127_7334843_1 1229172.JQFA01000002_gene2150 7.461e-91 306.0 COG0625@1|root,COG0625@2|Bacteria,1G1K3@1117|Cyanobacteria,1HBTT@1150|Oscillatoriales 1117|Cyanobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N GDHHQS3_k127_7334843_0 313596.RB2501_12577 2.312e-212 675.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer GDHHQS3_k127_7351840_5 1045855.DSC_09555 2.415e-61 214.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1X2X9@135614|Xanthomonadales 135614|Xanthomonadales V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran GDHHQS3_k127_7351840_1 1163407.UU7_10366 8.108e-122 419.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1X47B@135614|Xanthomonadales 135614|Xanthomonadales S DNA internalization-related competence protein ComEC Rec2 comA - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B GDHHQS3_k127_7351840_3 1121015.N789_12295 7.965e-75 256.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1X3F3@135614|Xanthomonadales 135614|Xanthomonadales U Biopolymer exbB2 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB GDHHQS3_k127_7351840_6 519989.ECTPHS_10701 3.807e-34 135.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales 135613|Chromatiales U PFAM Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD GDHHQS3_k127_7351840_0 754476.Q7A_2974 4.409e-165 540.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,45ZWJ@72273|Thiotrichales 72273|Thiotrichales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran GDHHQS3_k127_7351840_2 1384054.N790_00040 2.532e-79 278.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1X3DM@135614|Xanthomonadales 135614|Xanthomonadales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK GDHHQS3_k127_7351840_4 1121937.AUHJ01000005_gene2278 8.784e-64 226.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,464GE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 GDHHQS3_k127_737416_0 1129794.C427_0297 3.633e-234 741.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,464P3@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 GDHHQS3_k127_737416_4 1487953.JMKF01000068_gene3266 4.325e-22 98.0 COG1598@1|root,COG1598@2|Bacteria,1G9X3@1117|Cyanobacteria,1HDAI@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - HicB_lk_antitox GDHHQS3_k127_737416_5 13035.Dacsa_0101 2.74e-21 94.0 COG1724@1|root,COG1724@2|Bacteria,1G90Q@1117|Cyanobacteria 1117|Cyanobacteria N Periplasmic or secreted lipoprotein - - - - - - - - - - - - HicA_toxin GDHHQS3_k127_737416_7 366602.Caul_4023 1.493e-06 56.0 COG2353@1|root,COG2353@2|Bacteria,1RDEA@1224|Proteobacteria,2U7QJ@28211|Alphaproteobacteria,2KHSP@204458|Caulobacterales 204458|Caulobacterales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI GDHHQS3_k127_737416_6 69395.JQLZ01000012_gene4282 2.624e-13 70.0 COG2353@1|root,COG2353@2|Bacteria,1RDEA@1224|Proteobacteria,2U804@28211|Alphaproteobacteria,2KJTA@204458|Caulobacterales 204458|Caulobacterales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI GDHHQS3_k127_737416_2 999141.GME_12850 1.147e-35 138.0 COG3440@1|root,COG3440@2|Bacteria,1NGF6@1224|Proteobacteria,1RWDB@1236|Gammaproteobacteria,1XMRB@135619|Oceanospirillales 135619|Oceanospirillales L HNH endonuclease - - - - - - - - - - - - HNH_2 GDHHQS3_k127_737416_3 234267.Acid_0689 2.449e-35 137.0 COG3093@1|root,COG3093@2|Bacteria,3Y5MG@57723|Acidobacteria 2|Bacteria K TIGRFAM Addiction module antidote protein, HigA vapL - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3,HTH_31 GDHHQS3_k127_737416_1 1266914.ATUK01000012_gene312 3.579e-75 256.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C GDHHQS3_k127_742236_8 1408424.JHYI01000018_gene3195 1.254e-09 68.0 2DZYS@1|root,32VNG@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_742236_5 1123400.KB904769_gene2917 1.312e-39 153.0 COG3038@1|root,COG3038@2|Bacteria 2|Bacteria C cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - DUF3611,Ni_hydr_CYTB GDHHQS3_k127_742236_2 366602.Caul_1136 4.621e-103 367.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2KK80@204458|Caulobacterales 204458|Caulobacterales M TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_742236_6 349521.HCH_04415 1.176e-22 101.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 GDHHQS3_k127_742236_7 194439.CT1335 1.568e-17 91.0 COG4704@1|root,COG4704@2|Bacteria,1FFAT@1090|Chlorobi 1090|Chlorobi S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 GDHHQS3_k127_742236_1 221288.JH992901_gene2438 1.424e-114 383.0 COG1960@1|root,COG1960@2|Bacteria,1G3AS@1117|Cyanobacteria,1JM6F@1189|Stigonemataceae 1117|Cyanobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_742236_4 1163409.UUA_14524 1.771e-67 236.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1X4FI@135614|Xanthomonadales 135614|Xanthomonadales O protein-L-isoaspartate O-methyltransferase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT GDHHQS3_k127_742236_3 1286106.MPL1_03613 5.162e-89 309.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales 72273|Thiotrichales MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP GDHHQS3_k127_742236_0 1123253.AUBD01000011_gene2067 6.85e-118 392.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1X4GI@135614|Xanthomonadales 135614|Xanthomonadales M transferase waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N GDHHQS3_k127_7558924_6 525897.Dbac_1425 3.674e-12 70.0 COG0642@1|root,COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_9,Response_reg GDHHQS3_k127_7558924_2 391615.ABSJ01000027_gene180 1.995e-113 381.0 COG2199@1|root,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1J62M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF GDHHQS3_k127_7558924_4 1120977.JHUX01000009_gene2638 5.674e-50 182.0 COG2050@1|root,COG2050@2|Bacteria,1PP3M@1224|Proteobacteria,1SJ4P@1236|Gammaproteobacteria,3NMS8@468|Moraxellaceae 1236|Gammaproteobacteria Q Thioesterase-like superfamily - - - - - - - - - - - - 4HBT GDHHQS3_k127_7558924_3 1395571.TMS3_0120700 2.429e-87 289.0 COG2050@1|root,COG2050@2|Bacteria,1PP3M@1224|Proteobacteria,1SJ4P@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q protein possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT GDHHQS3_k127_7558924_0 1395571.TMS3_0120705 3.666e-187 603.0 COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,1RS1H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4872) - - - - - - - - - - - - BtrH_N,DUF4872 GDHHQS3_k127_7558924_1 1120977.JHUX01000009_gene2642 5.529e-141 455.0 COG3687@1|root,COG3687@2|Bacteria,1R8U6@1224|Proteobacteria,1RQUW@1236|Gammaproteobacteria,3NMY0@468|Moraxellaceae 1236|Gammaproteobacteria S Predicted metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol GDHHQS3_k127_7558924_5 296591.Bpro_5304 3.086e-20 90.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N GDHHQS3_k127_7602829_1 1121013.P873_07185 1.619e-111 367.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,1X38E@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA thioesterase tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 GDHHQS3_k127_7602829_2 1341151.ASZU01000004_gene320 3.959e-61 215.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4IQH5@91061|Bacilli,27DB5@186824|Thermoactinomycetaceae 91061|Bacilli O Peptide methionine sulfoxide reductase - - - - - - - - - - - - PMSR GDHHQS3_k127_7602829_3 225937.HP15_2679 2.806e-51 192.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,46768@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - DUF4124,SLT GDHHQS3_k127_7602829_0 1260251.SPISAL_04425 0.0 1036.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon GDHHQS3_k127_7636523_1 556269.ACDQ01000012_gene420 4.882e-18 90.0 COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria,2VVZ0@28216|Betaproteobacteria,474HE@75682|Oxalobacteraceae 28216|Betaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12976 - - - - ko00000,ko01000,ko01005 - - - PagL GDHHQS3_k127_7636523_0 1163617.SCD_n01957 7.275e-282 875.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria 28216|Betaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C GDHHQS3_k127_7689714_0 215803.DB30_7204 0.0 1084.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,42YZ6@68525|delta/epsilon subdivisions,2WU2X@28221|Deltaproteobacteria,2YXQD@29|Myxococcales 28221|Deltaproteobacteria E FAD dependent oxidoreductase central domain - - - - - - - - - - - - DAO,FAO_M,GCV_T,GCV_T_C GDHHQS3_k127_7689714_4 1040989.AWZU01000048_gene1470 4.672e-64 231.0 COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,3JV19@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha beta hydrolase MA20_16655 - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,DUF676,Hydrolase_4 GDHHQS3_k127_7689714_2 313606.M23134_00683 7.44e-138 456.0 COG4908@1|root,COG4908@2|Bacteria,4PMCQ@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf GDHHQS3_k127_7689714_3 1384054.N790_09325 2.444e-66 235.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1X57R@135614|Xanthomonadales 135614|Xanthomonadales S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 GDHHQS3_k127_7689714_1 1122134.KB893650_gene1081 1.231e-194 623.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XH5X@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GDHHQS3_k127_7724909_1 1123054.KB907702_gene1647 1.744e-74 256.0 COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,1X1ED@135613|Chromatiales 135613|Chromatiales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase GDHHQS3_k127_7724909_0 1121374.KB891576_gene624 4.456e-154 507.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 GDHHQS3_k127_7724909_2 314285.KT71_02627 1.763e-41 159.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_7784821_2 319003.Bra1253DRAFT_08264 3.048e-33 145.0 COG1696@1|root,COG1696@2|Bacteria,1R5WP@1224|Proteobacteria,2U7N8@28211|Alphaproteobacteria,3K3CQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Membrane protein involved in D-alanine export - - - - - - - - - - - - - GDHHQS3_k127_7784821_0 1032480.MLP_27670 9.998e-143 464.0 COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales 201174|Actinobacteria M Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - - - - - - - - - - ATP-grasp,ATP-grasp_4,CPSase_L_D2 GDHHQS3_k127_7784821_1 880073.Calab_3584 1.174e-98 332.0 COG0297@1|root,COG0297@2|Bacteria,2NQKG@2323|unclassified Bacteria 2|Bacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 GDHHQS3_k127_7787962_0 1137799.GZ78_10820 1.13e-261 901.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1XMIT@135619|Oceanospirillales 135619|Oceanospirillales M Salmonella virulence plasmid 65kDa B protein - - - - - - - - - - - - RHS_repeat,SpvB GDHHQS3_k127_7787962_1 926550.CLDAP_23540 2.947e-40 164.0 COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria 2|Bacteria S homoserine kinase activity gabT - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - APH,Aminotran_3,Peptidase_M23 GDHHQS3_k127_7825867_0 742767.HMPREF9456_02897 0.0 1387.0 COG3459@1|root,COG3459@2|Bacteria,4NIVN@976|Bacteroidetes,2FQ10@200643|Bacteroidia 976|Bacteroidetes G Putative carbohydrate binding domain - - - - - - - - - - - - Glyco_hydro_36,Glyco_transf_36,Glycoamylase GDHHQS3_k127_7825867_1 1123073.KB899241_gene2407 1.546e-18 85.0 2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1SCQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 GDHHQS3_k127_7842724_0 765911.Thivi_3483 2.988e-151 488.0 COG0457@1|root,COG4715@1|root,COG0457@2|Bacteria,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,1S0TU@1236|Gammaproteobacteria,1WXSB@135613|Chromatiales 135613|Chromatiales S Zinc finger, swim domain protein - - - - - - - - - - - - SWIM GDHHQS3_k127_7842724_2 637390.AFOH01000137_gene1778 1.795e-73 250.0 COG5611@1|root,COG5611@2|Bacteria,1RDUI@1224|Proteobacteria,1S7Z8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PIN domain - - - - - - - - - - - - PIN GDHHQS3_k127_7842724_4 562970.Btus_2098 2.823e-06 52.0 COG2002@1|root,COG2002@2|Bacteria,1VNHK@1239|Firmicutes,4HRZF@91061|Bacilli,27AKV@186823|Alicyclobacillaceae 91061|Bacilli K TIGRFAM transcriptional regulator, AbrB family - - - - - - - - - - - - MazE_antitoxin GDHHQS3_k127_7842724_3 1380394.JADL01000004_gene5908 2.917e-09 60.0 2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,2UGT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7842724_1 1469245.JFBG01000006_gene1597 5.742e-150 484.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Sarcosine oxidase, subunit beta soxB - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO GDHHQS3_k127_7856668_4 1123269.NX02_04875 5.81e-73 250.0 COG1228@1|root,COG1228@2|Bacteria,1R86X@1224|Proteobacteria,2U400@28211|Alphaproteobacteria,2K1TI@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 GDHHQS3_k127_7856668_0 1121104.AQXH01000001_gene1490 3.468e-290 925.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVPS@117747|Sphingobacteriia 976|Bacteroidetes M Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 GDHHQS3_k127_7856668_3 935840.JAEQ01000019_gene2102 9.524e-176 578.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,43H6S@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase - - 1.17.1.4,1.2.5.3 ko:K00087,ko:K03520 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_7856668_6 1125863.JAFN01000001_gene1570 2.908e-50 183.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,42S8R@68525|delta/epsilon subdivisions,2WNW6@28221|Deltaproteobacteria 28221|Deltaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 GDHHQS3_k127_7856668_7 330084.JNYZ01000067_gene8547 8.064e-41 162.0 COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria 2|Bacteria C Dehydrogenase - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 GDHHQS3_k127_7856668_5 1265313.HRUBRA_02101 1.758e-70 251.0 COG4447@1|root,COG4447@2|Bacteria,1R5ZV@1224|Proteobacteria,1S0FG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR GDHHQS3_k127_7856668_1 225937.HP15_4021 8.188e-289 908.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,465N7@72275|Alteromonadaceae 1236|Gammaproteobacteria S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL GDHHQS3_k127_7856668_2 1232410.KI421423_gene1931 2.804e-181 587.0 28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF1302 GDHHQS3_k127_7862587_2 420324.KI912071_gene8168 1.402e-67 237.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - Rhodanese GDHHQS3_k127_7862587_1 1280950.HJO_13121 9.741e-96 336.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_7862587_0 384765.SIAM614_18959 2.518e-163 521.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N GDHHQS3_k127_7862587_3 1125863.JAFN01000001_gene546 2.932e-34 135.0 COG2402@1|root,COG2402@2|Bacteria,1NK19@1224|Proteobacteria 1224|Proteobacteria S PIN domain - - - - - - - - - - - - PIN GDHHQS3_k127_7862587_4 1121430.JMLG01000037_gene136 0.0002535 46.0 28VBQ@1|root,2ZHEF@2|Bacteria,1W5WF@1239|Firmicutes,257CF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - GDHHQS3_k127_7873732_1 583355.Caka_1487 3.514e-176 576.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec GDHHQS3_k127_7873732_0 562970.Btus_1004 8.551e-189 604.0 COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,27820@186823|Alicyclobacillaceae 91061|Bacilli C Belongs to the malate synthase family aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase GDHHQS3_k127_7873732_2 1417296.U879_11855 4.557e-128 417.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM Mg2 transporter protein CorA family protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA GDHHQS3_k127_7873732_3 223283.PSPTO_3669 3.174e-13 70.0 COG3194@1|root,COG3194@2|Bacteria,1RE91@1224|Proteobacteria,1S4PA@1236|Gammaproteobacteria,1Z4N4@136849|Pseudomonas syringae group 1236|Gammaproteobacteria F Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source allA - 4.3.2.3 ko:K01483 ko00230,ko01100,map00230,map01100 - R00776 RC00153,RC00379 ko00000,ko00001,ko01000 - - - Ureidogly_lyase GDHHQS3_k127_7887704_5 1500894.JQNN01000001_gene4169 3.464e-10 63.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2VHWJ@28216|Betaproteobacteria,4725F@75682|Oxalobacteraceae 28216|Betaproteobacteria M BCCT, betaine/carnitine/choline family transporter betT - - ko:K02168,ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11,2.A.15.1.3,2.A.15.1.4 - - BCCT GDHHQS3_k127_7887704_1 1123399.AQVE01000001_gene684 3.094e-151 506.0 COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria 1236|Gammaproteobacteria UW Metallo-peptidase family M12B Reprolysin-like - - - - - - - - - - - - Reprolysin_3 GDHHQS3_k127_7887704_6 420662.Mpe_A0013 4.683e-10 62.0 2CIC8@1|root,33JK4@2|Bacteria,1NH5Z@1224|Proteobacteria,2VYDU@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7887704_3 247634.GPB2148_1942 7.125e-40 155.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,1JAKJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin GDHHQS3_k127_7887704_4 247634.GPB2148_2055 1.326e-27 121.0 2CEYX@1|root,30452@2|Bacteria,1QR0R@1224|Proteobacteria,1RTSI@1236|Gammaproteobacteria,1JBF2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7887704_2 1408473.JHXO01000010_gene3654 1.168e-74 257.0 COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia 976|Bacteroidetes F uracil phosphoribosyltransferase upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase GDHHQS3_k127_7887704_0 1168059.KB899087_gene2387 1.078e-199 633.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 GDHHQS3_k127_7905655_4 338966.Ppro_2745 5.122e-06 53.0 COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,42SIA@68525|delta/epsilon subdivisions,2X5AU@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos GDHHQS3_k127_7905655_2 1408419.JHYG01000002_gene1068 1.273e-43 176.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria 1224|Proteobacteria S Permease, YjgP YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ GDHHQS3_k127_7905655_0 391165.GbCGDNIH1_0249 5.723e-58 215.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria 1224|Proteobacteria S Permease, YjgP YjgQ family lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ GDHHQS3_k127_7905655_3 565045.NOR51B_2157 5.238e-07 59.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria 1224|Proteobacteria T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA GDHHQS3_k127_7905655_1 338966.Ppro_2774 2.459e-50 185.0 COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,42PKE@68525|delta/epsilon subdivisions,2WSF9@28221|Deltaproteobacteria 28221|Deltaproteobacteria M MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 GDHHQS3_k127_7919664_0 314285.KT71_05772 1.038e-169 550.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J8Q2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF2 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT GDHHQS3_k127_7919664_5 985054.JQEZ01000003_gene1478 1.406e-21 107.0 COG2327@1|root,COG2327@2|Bacteria 2|Bacteria S slime layer polysaccharide biosynthetic process - - - - - - - - - - - - PS_pyruv_trans GDHHQS3_k127_7919664_4 926550.CLDAP_28250 1.24e-37 145.0 COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 GDHHQS3_k127_7919664_3 1201288.M900_2198 1.379e-45 174.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,42T5R@68525|delta/epsilon subdivisions,2WX1F@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def_2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GDHHQS3_k127_7919664_1 314285.KT71_17566 1.76e-103 351.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1J76K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E amino acid - - - - - - - - - - - - AA_permease_2 GDHHQS3_k127_7919664_2 1283300.ATXB01000001_gene1712 2.563e-74 258.0 COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,1T2D2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Dienelactone hydrolase family - - - ko:K07100 - - - - ko00000 - - - DLH GDHHQS3_k127_7919664_6 1123320.KB889708_gene8179 5.512e-13 72.0 COG1028@1|root,COG1028@2|Bacteria,2GIVT@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_7934568_0 1244869.H261_14160 2.901e-227 709.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 GDHHQS3_k127_7934568_8 1244869.H261_12201 1.054e-45 173.0 COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria,2JYPY@204441|Rhodospirillales 28211|Alphaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - - - - - - - - - - - Fer2,Fer2_2 GDHHQS3_k127_7934568_3 1244869.H261_14170 1.445e-116 381.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TZIJ@28211|Alphaproteobacteria,2JZ34@204441|Rhodospirillales 204441|Rhodospirillales C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5 GDHHQS3_k127_7934568_5 1123320.KB889666_gene3115 1.705e-53 199.0 COG0045@1|root,COG0045@2|Bacteria 2|Bacteria C succinate-CoA ligase activity - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig GDHHQS3_k127_7934568_2 1123320.KB889666_gene3114 1.527e-147 480.0 COG1042@1|root,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria 201174|Actinobacteria C CoA-binding domain protein - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig GDHHQS3_k127_7934568_4 643648.Slip_2083 7.437e-81 283.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42KB1@68298|Syntrophomonadaceae 186801|Clostridia C PFAM acyl-CoA dehydrogenase domain protein - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N GDHHQS3_k127_7934568_7 292414.TM1040_1594 8.89e-46 179.0 COG0329@1|root,COG0329@2|Bacteria,1R73B@1224|Proteobacteria,2U0S8@28211|Alphaproteobacteria,4N9ZS@97050|Ruegeria 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GDHHQS3_k127_7934568_1 314278.NB231_05195 1.934e-157 503.0 COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1WZ4K@135613|Chromatiales 135613|Chromatiales L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 GDHHQS3_k127_7934568_9 270374.MELB17_22515 4.599e-22 96.0 COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1T7KM@1236|Gammaproteobacteria,46C37@72275|Alteromonadaceae 1236|Gammaproteobacteria L PFAM Integrase - - - - - - - - - - - - - GDHHQS3_k127_7934568_6 765912.Thimo_0061 4.138e-46 174.0 COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1S15T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Pfam Integrase core domain - - - - - - - - - - - - rve GDHHQS3_k127_7936763_4 1538295.JY96_16030 0.0001013 51.0 COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - GDHHQS3_k127_7936763_0 767434.Fraau_2811 1.719e-246 771.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1X31X@135614|Xanthomonadales 135614|Xanthomonadales C Electron transfer flavoprotein-ubiquinone oxidoreductase etf-QO - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8,Thi4 GDHHQS3_k127_7936763_2 84531.JMTZ01000021_gene3754 3.139e-99 329.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1X34D@135614|Xanthomonadales 135614|Xanthomonadales C electron transfer flavoprotein beta subunit etfB - - ko:K03521 - - - - ko00000 - - - ETF GDHHQS3_k127_7936763_1 1123253.AUBD01000012_gene973 1.953e-117 388.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1X4RW@135614|Xanthomonadales 135614|Xanthomonadales C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha GDHHQS3_k127_7936763_3 1123073.KB899241_gene2071 1.936e-32 130.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1X5HI@135614|Xanthomonadales 135614|Xanthomonadales I Acetyl-coenzyme A synthetase N-terminus - - - - - - - - - - - - ACAS_N,AMP-binding GDHHQS3_k127_7944425_0 1415780.JPOG01000001_gene1610 3.759e-211 661.0 COG0517@1|root,COG0538@1|root,COG0517@2|Bacteria,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1X3IR@135614|Xanthomonadales 135614|Xanthomonadales C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - CBS,Iso_dh GDHHQS3_k127_7944425_3 404589.Anae109_4248 3.254e-23 103.0 2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7944425_2 379066.GAU_1075 1.098e-55 199.0 COG0454@1|root,COG0454@2|Bacteria,1ZTWK@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 GDHHQS3_k127_7954077_3 1056820.KB900630_gene1473 1.858e-07 57.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1T3FE@1236|Gammaproteobacteria,2PPJ3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 GDHHQS3_k127_7954077_1 675812.VHA_002709 9.202e-37 148.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XTG2@135623|Vibrionales 135623|Vibrionales S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 GDHHQS3_k127_7954077_2 1415780.JPOG01000001_gene2436 2.332e-09 64.0 COG3197@1|root,COG3197@2|Bacteria,1QSIT@1224|Proteobacteria,1RW0B@1236|Gammaproteobacteria,1X8QU@135614|Xanthomonadales 135614|Xanthomonadales P Cytochrome oxidase maturation protein - - - - - - - - - - - - FixS GDHHQS3_k127_7954077_0 2340.JV46_28240 1.915e-94 327.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase GDHHQS3_k127_7954235_4 1385515.N791_12785 2.643e-104 351.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1XAMK@135614|Xanthomonadales 135614|Xanthomonadales S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 GDHHQS3_k127_7954235_3 1120970.AUBZ01000047_gene2618 2.159e-105 373.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,46D6F@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GDHHQS3_k127_7954235_5 1120970.AUBZ01000047_gene2617 4.515e-52 192.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S18G@1236|Gammaproteobacteria,466W4@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_7954235_6 208439.AJAP_30200 4.757e-44 167.0 COG2128@1|root,COG2128@2|Bacteria,2IFPC@201174|Actinobacteria,4EEQZ@85010|Pseudonocardiales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD GDHHQS3_k127_7954235_2 622637.KE124774_gene1454 5.397e-273 846.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P arylsulfatase A aslA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C GDHHQS3_k127_7954235_0 566466.NOR53_696 0.0 1086.0 COG3544@1|root,COG3544@2|Bacteria,1N0KY@1224|Proteobacteria,1SBTF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 GDHHQS3_k127_7954235_1 1095769.CAHF01000006_gene1883 1.077e-321 1005.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VNZD@28216|Betaproteobacteria,4764S@75682|Oxalobacteraceae 28216|Betaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon2 - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C GDHHQS3_k127_7954235_7 392499.Swit_1147 2.989e-29 121.0 COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2UE1E@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the small heat shock protein (HSP20) family MA20_45160 - - - - - - - - - - - HSP20 GDHHQS3_k127_7954235_9 105559.Nwat_1964 3.238e-18 98.0 2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7954235_8 472759.Nhal_0280 2.584e-20 105.0 COG2335@1|root,COG2335@2|Bacteria 2|Bacteria M COG2335, Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - CHRD,Fasciclin GDHHQS3_k127_7954235_10 1077972.ARGLB_080_00570 3.773e-06 59.0 COG4932@1|root,COG4932@2|Bacteria,2GXWA@201174|Actinobacteria,1W96H@1268|Micrococcaceae 201174|Actinobacteria M Belongs to the peptidase S8 family - - - - - - - - - - - - CarboxypepD_reg GDHHQS3_k127_7968341_3 747.DR93_640 1.057e-30 128.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1Y8G4@135625|Pasteurellales 135625|Pasteurellales H 5-formyltetrahydrofolate cyclo-ligase Z012_01860 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig GDHHQS3_k127_7968341_2 857087.Metme_1141 6.612e-63 220.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XEYU@135618|Methylococcales 135618|Methylococcales S EVE domain - - - - - - - - - - - - EVE GDHHQS3_k127_7968341_0 435908.IDSA_10525 5.805e-82 281.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,2QFMI@267893|Idiomarinaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A GDHHQS3_k127_7968341_1 643867.Ftrac_2945 8.01e-78 266.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin GDHHQS3_k127_7972954_3 1454004.AW11_02526 5.804e-48 197.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2W7C4@28216|Betaproteobacteria,1KR2P@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M AsmA family - - - ko:K07290 - - - - ko00000 9.B.121 - - AsmA GDHHQS3_k127_7972954_2 1384054.N790_03995 6.532e-70 254.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XCGD@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 GDHHQS3_k127_7972954_0 396588.Tgr7_0704 0.0 1052.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran GDHHQS3_k127_7972954_4 1161401.ASJA01000009_gene1796 2.701e-20 102.0 2EH1A@1|root,33ATA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GDHHQS3_k127_7972954_1 1415780.JPOG01000001_gene2121 1.583e-71 252.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,1X3E7@135614|Xanthomonadales 135614|Xanthomonadales S Methyltransferase - - - - - - - - - - - - - GDHHQS3_k127_7972954_5 1042377.AFPJ01000028_gene2262 1.358e-12 70.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,464G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GDHHQS3_k127_7989499_3 85643.Tmz1t_2728 4.895e-56 199.0 COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,2KU66@206389|Rhodocyclales 206389|Rhodocyclales S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - GDHHQS3_k127_7989499_2 1131553.JIBI01000026_gene58 3.993e-56 204.0 COG0500@1|root,COG2226@2|Bacteria,1PE85@1224|Proteobacteria,2W92M@28216|Betaproteobacteria,373FB@32003|Nitrosomonadales 28216|Betaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_25 GDHHQS3_k127_7989499_4 1161401.ASJA01000001_gene260 3.017e-51 194.0 COG4244@1|root,COG4244@2|Bacteria,1R2SC@1224|Proteobacteria,2UJ91@28211|Alphaproteobacteria,440SI@69657|Hyphomonadaceae 2|Bacteria S Predicted membrane protein (DUF2231) - - - - - - - - - - - - DUF2231,SnoaL_3 GDHHQS3_k127_7989499_5 640081.Dsui_0097 7.769e-36 142.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2VSDN@28216|Betaproteobacteria,2KWKP@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function, DUF - - - - - - - - - - - - DUF411 GDHHQS3_k127_7989499_0 1132855.KB913035_gene1495 0.0 1851.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KMG8@206350|Nitrosomonadales 28216|Betaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran GDHHQS3_k127_7989499_1 1132855.KB913035_gene1494 1.394e-191 604.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KNV2@206350|Nitrosomonadales 206350|Nitrosomonadales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - HlyD_D23 GDHHQS3_k127_7993743_0 1537917.JU82_07535 6.466e-225 709.0 COG0028@1|root,COG0028@2|Bacteria,1MYUS@1224|Proteobacteria,42QE8@68525|delta/epsilon subdivisions,2YNKA@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_7993743_1 243924.LT42_22430 5.417e-35 138.0 COG2246@1|root,COG2246@2|Bacteria,1NENT@1224|Proteobacteria 1224|Proteobacteria S GtrA-like protein - - - - - - - - - - - - GtrA GDHHQS3_k127_7993743_2 114615.BRADO5185 7.938e-27 128.0 COG4485@1|root,COG4485@2|Bacteria 2|Bacteria M Bacterial membrane protein, YfhO - - - - - - - - - - - - YfhO GDHHQS3_k127_7997817_0 671143.DAMO_3072 9.146e-71 246.0 COG0558@1|root,COG0558@2|Bacteria 2|Bacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family spsI GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0016780 2.7.7.74,2.7.8.34 ko:K07281,ko:K07291 ko00562,map00562 - R09669,R09670 RC00002,RC00078 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf,NTP_transf_3 GDHHQS3_k127_7997817_1 1283300.ATXB01000001_gene1372 5.433e-65 234.0 COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria,1S4B3@1236|Gammaproteobacteria 1236|Gammaproteobacteria I lipid kinase activity - - - - - - - - - - - - Mmp37 GDHHQS3_k127_7997817_2 1283300.ATXB01000001_gene564 6.027e-27 116.0 COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,1RMK6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Polysaccharide biosynthesis protein yghQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 GDHHQS3_k127_8005138_2 493475.GARC_3527 3.051e-66 228.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,466WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 GDHHQS3_k127_8005138_3 1121104.AQXH01000004_gene99 1.214e-43 167.0 COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1J0HU@117747|Sphingobacteriia 976|Bacteroidetes S SMART Metal-dependent phosphohydrolase, HD region - - - - - - - - - - - - HD GDHHQS3_k127_8005138_0 1479238.JQMZ01000001_gene1005 4.821e-95 336.0 COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,2U3NK@28211|Alphaproteobacteria,43YWS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 GDHHQS3_k127_8005138_1 1123401.JHYQ01000009_gene2282 8.06e-76 263.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) dcsG - - - - - - - - - - - GSH-S_ATP,RimK GDHHQS3_k127_805243_2 118166.JH976537_gene974 2.286e-22 98.0 COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria,1HCPC@1150|Oscillatoriales 1117|Cyanobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin GDHHQS3_k127_805243_3 272134.KB731324_gene3016 4.591e-19 89.0 COG2929@1|root,COG2929@2|Bacteria,1G8FA@1117|Cyanobacteria,1HHKT@1150|Oscillatoriales 1117|Cyanobacteria S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - ko:K09803 - - - - ko00000 - - - BrnT_toxin GDHHQS3_k127_805243_1 1280950.HJO_13121 7.693e-91 322.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C GDHHQS3_k127_805243_0 1122603.ATVI01000005_gene3497 7.106e-111 382.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_805243_4 314285.KT71_02627 3.416e-12 68.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - GDHHQS3_k127_8058204_2 1500890.JQNL01000001_gene916 2.309e-21 98.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1X3MH@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf GDHHQS3_k127_8058204_1 1384056.N787_04205 1.211e-42 161.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 GDHHQS3_k127_8058204_0 686340.Metal_2510 4.826e-209 662.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XEJP@135618|Methylococcales 135618|Methylococcales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 GDHHQS3_k127_8073262_0 1157635.KB892006_gene3201 4.223e-89 301.0 COG1024@1|root,COG1024@2|Bacteria,2IBBD@201174|Actinobacteria 201174|Actinobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - - ECH_1 GDHHQS3_k127_8073262_1 1448860.BBJO01000014_gene1338 1.047e-74 271.0 COG0318@1|root,arCOG00856@2157|Archaea,2XW27@28890|Euryarchaeota,23RYA@183963|Halobacteria 183963|Halobacteria I AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C GDHHQS3_k127_8073262_2 983920.Y88_3404 1.395e-46 174.0 COG4206@1|root,COG4206@2|Bacteria,1QVV2@1224|Proteobacteria 1224|Proteobacteria H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_8077136_0 1122134.KB893650_gene1117 6.03e-177 573.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 GDHHQS3_k127_8077136_1 1173264.KI913949_gene2441 7.589e-38 147.0 2CD0I@1|root,32RWS@2|Bacteria,1G74B@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF4399) - - - - - - - - - - - - DUF4399 GDHHQS3_k127_8077136_2 876044.IMCC3088_108 1.137e-29 123.0 COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,1J661@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C GDHHQS3_k127_8091565_0 523791.Kkor_0209 1.431e-190 612.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C GDHHQS3_k127_8095997_0 269796.Rru_A0570 6.044e-142 455.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2JPAV@204441|Rhodospirillales 204441|Rhodospirillales H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 GDHHQS3_k127_8095997_1 111780.Sta7437_0893 1.372e-28 117.0 COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales 1117|Cyanobacteria V ABC-type multidrug transport system ATPase and permease - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GDHHQS3_k127_8116406_1 1207063.P24_18112 2.016e-87 294.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,2JSD0@204441|Rhodospirillales 204441|Rhodospirillales I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase GDHHQS3_k127_8116406_2 1049564.TevJSym_ae00640 5.291e-76 260.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator, ArsR family - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese GDHHQS3_k127_8116406_0 1120985.AUMI01000018_gene2985 2.824e-123 407.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4H20F@909932|Negativicutes 909932|Negativicutes E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - Aminotran_1_2 GDHHQS3_k127_8116406_3 1323663.AROI01000035_gene1340 6.904e-53 196.0 COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,1SBM0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_2 GDHHQS3_k127_8131234_0 1123240.ATVO01000005_gene1973 2.332e-115 379.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales 204457|Sphingomonadales L alcohol dehydrogenase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N GDHHQS3_k127_8131234_2 1158756.AQXQ01000009_gene1181 1.334e-52 190.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria,1X1DX@135613|Chromatiales 135613|Chromatiales M 17 kDa outer membrane surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti GDHHQS3_k127_8131234_1 1232410.KI421424_gene1749 2.547e-89 308.0 COG0412@1|root,COG0412@2|Bacteria,1QW3K@1224|Proteobacteria,43C4E@68525|delta/epsilon subdivisions,2X7EV@28221|Deltaproteobacteria,43S1I@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Dienelactone hydrolase - - - - - - - - - - - - - GDHHQS3_k127_8131234_3 314287.GB2207_03060 8.283e-35 134.0 COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1J54J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid desaturase alkB1 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase GDHHQS3_k127_8137088_2 1123073.KB899241_gene1744 1.367e-23 100.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P GDHHQS3_k127_8137088_1 765914.ThisiDRAFT_0772 2.071e-79 277.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X102@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE GDHHQS3_k127_8137088_0 1385517.N800_14715 3.818e-198 623.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N GDHHQS3_k127_8151849_0 565045.NOR51B_2574 1.885e-199 638.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase - - - - - - - - - - - - PQQ,PQQ_2 GDHHQS3_k127_8151849_3 1430440.MGMSRv2_4162 2.424e-35 145.0 COG0596@1|root,COG0596@2|Bacteria,1QXP7@1224|Proteobacteria,2UBA7@28211|Alphaproteobacteria,2JU5X@204441|Rhodospirillales 204441|Rhodospirillales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 GDHHQS3_k127_8151849_2 1347369.CCAD010000086_gene1738 2.483e-82 287.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus 91061|Bacilli I COG0657 Esterase lipase - - - - - - - - - - - - Abhydrolase_3 GDHHQS3_k127_8151849_4 1121438.JNJA01000010_gene1993 2.805e-23 110.0 COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,42TIX@68525|delta/epsilon subdivisions,2WP2M@28221|Deltaproteobacteria,2MAUW@213115|Desulfovibrionales 28221|Deltaproteobacteria K AraC protein, arabinose-binding - - - - - - - - - - - - AraC_binding,HTH_18 GDHHQS3_k127_8151849_1 1280949.HAD_10030 5.323e-183 597.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec GDHHQS3_k127_8180671_18 56780.SYN_02733 1.435e-11 66.0 COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria,42W9Y@68525|delta/epsilon subdivisions,2WSG7@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 GDHHQS3_k127_8180671_11 234267.Acid_2061 3.209e-50 195.0 COG3550@1|root,COG3550@2|Bacteria,3Y4V9@57723|Acidobacteria 57723|Acidobacteria S HipA N-terminal domain - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C GDHHQS3_k127_8180671_5 56110.Oscil6304_5587 9.044e-74 264.0 COG2848@1|root,COG2848@2|Bacteria,1G3IK@1117|Cyanobacteria 1117|Cyanobacteria S Uncharacterised ACR (DUF711) - - - ko:K09157 - - - - ko00000 - - - DUF711 GDHHQS3_k127_8180671_2 1282876.BAOK01000001_gene1823 1.208e-122 399.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH GDHHQS3_k127_8180671_8 565045.NOR51B_2818 7.067e-61 225.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K07685 ko02020,map02020 M00472 - - ko00000,ko00001,ko00002,ko02022 - - - Autoind_bind,GerE,Response_reg GDHHQS3_k127_8180671_0 565045.NOR51B_1387 0.0 1086.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria,1J84P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_8180671_12 392499.Swit_0770 2.07e-43 164.0 COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2U1WR@28211|Alphaproteobacteria,2K70M@204457|Sphingomonadales 204457|Sphingomonadales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase_4 GDHHQS3_k127_8180671_1 565045.NOR51B_2791 2.331e-302 934.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H acetolactate synthase - - 1.2.5.1,2.2.1.6 ko:K00156,ko:K01652 ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648 RC00027,RC00106,RC00860,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GDHHQS3_k127_8180671_4 392499.Swit_0769 3.936e-78 269.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,2K35D@204457|Sphingomonadales 204457|Sphingomonadales IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short_C2 GDHHQS3_k127_8180671_3 502025.Hoch_1142 1.089e-101 346.0 COG2963@1|root,COG2963@2|Bacteria,1NMA3@1224|Proteobacteria,434KN@68525|delta/epsilon subdivisions,2WYXX@28221|Deltaproteobacteria,2Z0W6@29|Myxococcales 28221|Deltaproteobacteria L transposase activity - - - - - - - - - - - - - GDHHQS3_k127_8180671_16 330214.NIDE2935 1.014e-20 93.0 COG1724@1|root,COG1724@2|Bacteria 2|Bacteria N mRNA binding - - - - - - - - - - - - HicA_toxin GDHHQS3_k127_8180671_14 272134.KB731324_gene2076 1.463e-22 100.0 COG1598@1|root,COG1598@2|Bacteria,1G9D5@1117|Cyanobacteria,1HDHB@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - GDHHQS3_k127_8180671_15 401053.AciPR4_3620 2.852e-21 99.0 COG1506@1|root,COG1506@2|Bacteria,3Y798@57723|Acidobacteria,2JKSR@204432|Acidobacteriia 204432|Acidobacteriia E peptidase - - - - - - - - - - - - - GDHHQS3_k127_8180671_17 1038859.AXAU01000011_gene2412 1.275e-16 87.0 2EH8B@1|root,33B05@2|Bacteria,1NQEC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_8180671_9 862908.BMS_1178 3.639e-60 214.0 COG0625@1|root,COG0625@2|Bacteria,1PEUK@1224|Proteobacteria,437SY@68525|delta/epsilon subdivisions,2MUK6@213481|Bdellovibrionales,2X324@28221|Deltaproteobacteria 213481|Bdellovibrionales H Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N GDHHQS3_k127_8180671_13 1382359.JIAL01000001_gene658 1.114e-35 142.0 COG1733@1|root,COG1733@2|Bacteria,3Y7XV@57723|Acidobacteria,2JN1Y@204432|Acidobacteriia 204432|Acidobacteriia K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GDHHQS3_k127_8180671_7 288000.BBta_1820 9.014e-63 220.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TUGP@28211|Alphaproteobacteria,3JTRR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain MA20_05155 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 GDHHQS3_k127_8180671_6 1280953.HOC_05029 4.577e-66 234.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2TRRV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG2513 PEP phosphonomutase and related enzymes - - - - - - - - - - - - PEP_mutase GDHHQS3_k127_8180671_10 530564.Psta_1556 1.128e-56 205.0 29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - GDHHQS3_k127_8191321_1 331869.BAL199_07498 1.197e-128 419.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria 28211|Alphaproteobacteria EQ N-methylhydantoinase B acetone carboxylase alpha subunit - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B GDHHQS3_k127_8191321_2 338969.Rfer_2416 1.161e-108 362.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2VSDG@28216|Betaproteobacteria,4AFT8@80864|Comamonadaceae 28216|Betaproteobacteria I Steryl acetyl hydrolase - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 GDHHQS3_k127_8191321_0 1249627.D779_1090 2.416e-151 482.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1WX7Z@135613|Chromatiales 135613|Chromatiales HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK GDHHQS3_k127_8191321_4 1396858.Q666_04845 3.419e-48 177.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,467C1@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease GDHHQS3_k127_8191321_3 1121090.KB894695_gene1399 8.812e-70 252.0 COG1457@1|root,COG1457@2|Bacteria,1UNJV@1239|Firmicutes,4IK09@91061|Bacilli,1ZEY6@1386|Bacillus 1239|Firmicutes F Permease for cytosine/purines, uracil, thiamine, allantoin - - - - - - - - - - - - Transp_cyt_pur GDHHQS3_k127_8192470_0 1123519.PSJM300_18090 6.003e-44 162.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1Z04B@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_2953 GCV_T,GCV_T_C GDHHQS3_k127_8192470_2 1123073.KB899241_gene1965 7.829e-41 157.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1X8MB@135614|Xanthomonadales 135614|Xanthomonadales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA GDHHQS3_k127_8192470_3 517417.Cpar_1037 9.333e-14 74.0 2E3QA@1|root,32YN8@2|Bacteria,1FFJG@1090|Chlorobi 1090|Chlorobi M Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 GDHHQS3_k127_8192470_1 1123279.ATUS01000003_gene527 6.046e-41 161.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1J75U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 GDHHQS3_k127_8198496_3 375286.mma_2819 3.454e-69 239.0 COG3791@1|root,COG3791@2|Bacteria,1MX4A@1224|Proteobacteria,2VQXV@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione gfa - 4.4.1.22 ko:K03396 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R06982 RC00069,RC01707 ko00000,ko00001,ko01000 - - - GFA GDHHQS3_k127_8198496_0 566466.NOR53_3605 5.205e-112 372.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1J59R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase GDHHQS3_k127_8198496_1 314285.KT71_09622 4.381e-105 349.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,1J7HT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Methyltransferase - - - - - - - - - - - - - GDHHQS3_k127_8198496_2 153948.NAL212_2914 9.168e-77 265.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,2W832@28216|Betaproteobacteria,372AS@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 GDHHQS3_k127_8198496_4 1265313.HRUBRA_02122 6.489e-54 191.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1J4KZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases yliI - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH GDHHQS3_k127_8199171_2 1122604.JONR01000008_gene2172 8.822e-57 201.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XCA1@135614|Xanthomonadales 135614|Xanthomonadales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg GDHHQS3_k127_8199171_0 261292.Nit79A3_0852 8.351e-124 404.0 COG3437@1|root,COG3437@2|Bacteria,1PDX2@1224|Proteobacteria,2VMIS@28216|Betaproteobacteria,372X7@32003|Nitrosomonadales 28216|Betaproteobacteria KT cheY-homologous receiver domain - - - ko:K07814 - - - - ko00000,ko02022 - - - Response_reg GDHHQS3_k127_8199171_1 1458427.BAWN01000006_gene361 1.058e-96 323.0 COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae 28216|Betaproteobacteria K Crp Fnr family - - - - - - - - - - - - HTH_Crp_2,cNMP_binding GDHHQS3_k127_8199171_3 1079460.ATTQ01000016_gene5421 1.389e-50 186.0 COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae 28211|Alphaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth GDHHQS3_k127_8236587_1 768066.HELO_2294 5.269e-41 157.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1XJ85@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DnaA family. HdA subfamily - - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA GDHHQS3_k127_8236587_0 1499967.BAYZ01000058_gene4761 1.079e-135 436.0 COG2820@1|root,COG2820@2|Bacteria,2NQCN@2323|unclassified Bacteria 2|Bacteria F Phosphorylase superfamily amn - 2.4.2.3,3.2.2.4 ko:K00757,ko:K01241 ko00230,ko00240,ko00983,ko01100,map00230,map00240,map00983,map01100 - R00182,R01876,R02484,R08229 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 GDHHQS3_k127_8236587_2 767434.Fraau_2329 1.218e-10 70.0 2CA5V@1|root,2Z9I7@2|Bacteria,1R50M@1224|Proteobacteria,1THFK@1236|Gammaproteobacteria,1X4JB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_8335876_7 626887.J057_09996 2.09e-19 87.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,465B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family XCC2717 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C GDHHQS3_k127_8335876_8 240015.ACP_3138 2.814e-18 85.0 COG3384@1|root,COG3384@2|Bacteria,3Y57M@57723|Acidobacteria 57723|Acidobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB GDHHQS3_k127_8335876_6 572477.Alvin_2092 4.216e-27 119.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,1WWSI@135613|Chromatiales 135613|Chromatiales L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 GDHHQS3_k127_8335876_5 1197906.CAJQ02000010_gene3277 4.806e-67 239.0 2EE0X@1|root,337VQ@2|Bacteria,1N7Y3@1224|Proteobacteria,2UGEB@28211|Alphaproteobacteria,3K4QF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - GDHHQS3_k127_8335876_10 2340.JV46_16940 1.529e-05 58.0 COG1141@1|root,COG1141@2|Bacteria 2|Bacteria C electron transfer activity - - 1.2.7.1 ko:K03737,ko:K05337 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C GDHHQS3_k127_8335876_4 1187851.A33M_4209 4.525e-84 306.0 COG1013@1|root,COG1013@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - - - - - - - - - - Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C GDHHQS3_k127_8335876_3 1049564.TevJSym_bb00040 1.395e-96 326.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C GDHHQS3_k127_8335876_1 1049564.TevJSym_bb00050 1.187e-222 708.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N GDHHQS3_k127_8335876_0 1187851.A33M_4208 4.117e-225 707.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum 28211|Alphaproteobacteria E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2 GDHHQS3_k127_8335876_2 1187851.A33M_4207 1.284e-145 466.0 COG0543@1|root,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding gltA - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 ko:K00266,ko:K00528,ko:K02823 ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248,R10159 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2 GDHHQS3_k127_8335876_9 306263.Cla_0288 7.482e-07 53.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S hmm pf04305 - - - - - - - - - - - - DUF455 GDHHQS3_k127_8341715_9 1123072.AUDH01000006_gene3323 1.183e-06 52.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,2JPY6@204441|Rhodospirillales 204441|Rhodospirillales L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding - - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase GDHHQS3_k127_8341715_5 1123073.KB899241_gene3005 9.705e-52 185.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1X6E5@135614|Xanthomonadales 135614|Xanthomonadales C Iron-sulfur cluster insertion protein ErpA erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn GDHHQS3_k127_8341715_7 1045855.DSC_14270 4.209e-23 110.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1X665@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - GDHHQS3_k127_8341715_6 391615.ABSJ01000022_gene286 3.153e-42 163.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1J6C5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 GDHHQS3_k127_8341715_1 2340.JV46_24910 2.007e-98 329.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1J5ZG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P GDHHQS3_k127_8341715_3 1234364.AMSF01000055_gene1099 3.081e-71 250.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1X3RK@135614|Xanthomonadales 135614|Xanthomonadales L ADP-ribose diphosphatase nudE - - ko:K08312 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX GDHHQS3_k127_8341715_2 713586.KB900536_gene1483 3.512e-94 316.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,1RMVD@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Inositol monophosphatase - - 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P GDHHQS3_k127_8341715_4 1384056.N787_14000 1.102e-58 214.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales 135614|Xanthomonadales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA GDHHQS3_k127_8341715_8 1121015.N789_09050 6.8e-19 95.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X71Z@135614|Xanthomonadales 135614|Xanthomonadales NT Two component signalling adaptor domain - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW GDHHQS3_k127_8341715_0 666685.R2APBS1_0864 2.292e-107 357.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg GDHHQS3_k127_8394050_5 1216966.BAUC01000002_gene2686 1.321e-05 49.0 COG1457@1|root,COG1457@2|Bacteria,1PNMU@1224|Proteobacteria,1RPMZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F permease - - - - - - - - - - - - Transp_cyt_pur GDHHQS3_k127_8394050_0 1380394.JADL01000003_gene5185 1.258e-213 679.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2JPYI@204441|Rhodospirillales 204441|Rhodospirillales IQ AMP-binding enzyme - - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding GDHHQS3_k127_8394050_4 316055.RPE_3219 2.162e-26 111.0 COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2TUBT@28211|Alphaproteobacteria,3K2FJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Thiolase, C-terminal domain - - - - - - - - - - - - Thiolase_C,Thiolase_N GDHHQS3_k127_8394050_1 13689.BV96_00587 6.218e-160 514.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,2K261@204457|Sphingomonadales 204457|Sphingomonadales EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_4,TRI12 GDHHQS3_k127_8394050_2 555779.Dthio_PD3715 1.327e-138 450.0 COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MAH6@213115|Desulfovibrionales 28221|Deltaproteobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GDHHQS3_k127_8394050_3 598659.NAMH_1015 2.635e-91 307.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF GDHHQS3_k127_8415999_1 1280949.HAD_14109 1.406e-157 503.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases MA20_01050 - 1.17.1.10 ko:K15022 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 M00377 R00134 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3 GDHHQS3_k127_8415999_0 1280953.HOC_18124 2.067e-260 814.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,43Z43@69657|Hyphomonadaceae 28211|Alphaproteobacteria C pyruvate flavodoxin ferredoxin oxidoreductase MA20_01045 - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N GDHHQS3_k127_843598_1 333138.LQ50_20165 6.45e-41 162.0 2A6Y1@1|root,30VSZ@2|Bacteria,1UBKQ@1239|Firmicutes,4IN0U@91061|Bacilli,1ZMG5@1386|Bacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 GDHHQS3_k127_843598_0 983545.Glaag_4219 7.756e-167 540.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,465DH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase dimerisation domain - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 GDHHQS3_k127_8442944_1 531844.FIC_01836 2.423e-94 315.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,4067R@61432|unclassified Flavobacteriaceae 976|Bacteroidetes C Aldehyde dehydrogenase family aldB - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_8442944_2 1122603.ATVI01000007_gene1457 7.569e-88 318.0 COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,1SZ1B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 GDHHQS3_k127_8442944_0 1121374.KB891575_gene1256 3.958e-173 554.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C GDHHQS3_k127_8442944_3 1123519.PSJM300_13320 1.16e-68 238.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,1Z2J6@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C L-lactate dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh GDHHQS3_k127_8483437_9 748247.AZKH_p0450 1.613e-05 53.0 COG0705@1|root,COG0705@2|Bacteria,1RJYI@1224|Proteobacteria,2W1AJ@28216|Betaproteobacteria,2KXTX@206389|Rhodocyclales 206389|Rhodocyclales S Rhomboid family - - - - - - - - - - - - Rhomboid GDHHQS3_k127_8483437_3 1265505.ATUG01000002_gene1088 9.923e-71 247.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales 28221|Deltaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GDHHQS3_k127_8483437_5 765911.Thivi_1756 1.125e-47 177.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,1WYB2@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 GDHHQS3_k127_8483437_4 1123257.AUFV01000002_gene2682 3.562e-54 200.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1X5XX@135614|Xanthomonadales 135614|Xanthomonadales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N GDHHQS3_k127_8483437_0 1242864.D187_010399 3.969e-223 711.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,42S4X@68525|delta/epsilon subdivisions,2WNPW@28221|Deltaproteobacteria,2YU9Y@29|Myxococcales 28221|Deltaproteobacteria O Peptidase family M13 - - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N GDHHQS3_k127_8483437_6 1123253.AUBD01000005_gene128 2.806e-35 144.0 COG1595@1|root,COG1595@2|Bacteria,1QDHS@1224|Proteobacteria,1SS07@1236|Gammaproteobacteria,1X6DE@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 GDHHQS3_k127_8483437_7 1121013.P873_05025 5.904e-26 122.0 COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales 135614|Xanthomonadales O PDZ domain - - - - - - - - - - - - PDZ_2 GDHHQS3_k127_8483437_2 550540.Fbal_3052 5.461e-110 364.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Co Zn Cd cation transporters - - - - - - - - - - - - Cation_efflux,ZT_dimer GDHHQS3_k127_8483437_1 742159.HMPREF0004_0368 2.488e-202 638.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,3T2A2@506|Alcaligenaceae 28216|Betaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 GDHHQS3_k127_8483437_8 435908.IDSA_00735 4.274e-08 61.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,2QG2K@267893|Idiomarinaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N GDHHQS3_k127_8528195_1 323261.Noc_0676 3.523e-77 268.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1WYD3@135613|Chromatiales 135613|Chromatiales K PFAM Response regulator receiver domain - - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GDHHQS3_k127_8528195_2 1094715.CM001373_gene997 1.883e-65 240.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,1JCC4@118969|Legionellales 118969|Legionellales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA GDHHQS3_k127_8528195_0 743721.Psesu_1733 2.528e-97 327.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1X456@135614|Xanthomonadales 135614|Xanthomonadales J Elongation factor P--(R)-beta-lysine ligase lysS - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 GDHHQS3_k127_8562629_10 1380358.JADJ01000031_gene4177 1.115e-31 132.0 2DF7Q@1|root,32U4W@2|Bacteria,1N0SY@1224|Proteobacteria,1SAUR@1236|Gammaproteobacteria,1XQ16@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - GDHHQS3_k127_8562629_0 767434.Fraau_1882 2.005e-243 765.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1X4G4@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase GDHHQS3_k127_8562629_2 1384056.N787_05435 1.11e-134 435.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1X45V@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 GDHHQS3_k127_8562629_1 1123073.KB899242_gene1436 6.78e-185 586.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1X2YM@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N GDHHQS3_k127_8562629_11 1260251.SPISAL_04395 6.243e-21 95.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1WZ9J@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC GDHHQS3_k127_8562629_8 713586.KB900536_gene114 6.177e-53 196.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales 135613|Chromatiales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD GDHHQS3_k127_8562629_6 1094184.KWO_0111450 2.477e-65 227.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1X5Z0@135614|Xanthomonadales 135614|Xanthomonadales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB GDHHQS3_k127_8562629_12 216816.GS08_00325 6.007e-07 57.0 COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales 201174|Actinobacteria T Protein of unknown function (DUF2662) fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - - - - - - - - - - DUF3662,FHA,Yop-YscD_cpl GDHHQS3_k127_8562629_9 391625.PPSIR1_30385 2.89e-40 156.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,43APS@68525|delta/epsilon subdivisions,2X63H@28221|Deltaproteobacteria,2YVYC@29|Myxococcales 28221|Deltaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 GDHHQS3_k127_8562629_7 870187.Thini_4144 4.447e-57 205.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - GDHHQS3_k127_8562629_3 913325.N799_12770 2.203e-107 360.0 COG4585@1|root,COG4585@2|Bacteria,1RAKD@1224|Proteobacteria,1S33T@1236|Gammaproteobacteria,1X3EC@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - HisKA_3 GDHHQS3_k127_8562629_4 913325.N799_12775 2.947e-101 334.0 COG2197@1|root,COG2197@2|Bacteria,1RAQG@1224|Proteobacteria,1S31E@1236|Gammaproteobacteria,1X4HP@135614|Xanthomonadales 135614|Xanthomonadales K regulator - - - - - - - - - - - - GerE,Response_reg GDHHQS3_k127_8562629_5 1123073.KB899242_gene1478 1.542e-85 287.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X3JY@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GDHHQS3_k127_8583861_0 296591.Bpro_2390 1.066e-160 514.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg GDHHQS3_k127_8583861_1 1207063.P24_01480 1.524e-93 324.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2TSQ2@28211|Alphaproteobacteria,2JRD2@204441|Rhodospirillales 204441|Rhodospirillales P protein involved in response to NO - - - ko:K07234 - - - - ko00000 - - - NnrS GDHHQS3_k127_8583861_5 211586.SO_0850 1.408e-15 90.0 COG4726@1|root,COG4726@2|Bacteria,1R7GS@1224|Proteobacteria,1RS5Q@1236|Gammaproteobacteria,2QAIR@267890|Shewanellaceae 1236|Gammaproteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - Bactofilin GDHHQS3_k127_8583861_2 1283300.ATXB01000001_gene80 2.534e-41 170.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1XF4P@135618|Methylococcales 135618|Methylococcales NU Type IV Pilus-assembly protein W - - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW GDHHQS3_k127_8583861_4 1268635.Loa_02136 1.075e-20 96.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1JE30@118969|Legionellales 118969|Legionellales NU Prokaryotic N-terminal methylation motif - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl GDHHQS3_k127_8623376_2 596153.Alide_2964 9.484e-27 114.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,4ACUE@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM L-carnitine dehydratase bile acid-inducible protein F - - 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 GDHHQS3_k127_8623376_0 1205753.A989_09918 6.411e-123 402.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1X44J@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus GDHHQS3_k127_8623376_1 1121013.P873_07835 3.495e-87 301.0 COG4874@1|root,COG4874@2|Bacteria,1N05R@1224|Proteobacteria,1S34T@1236|Gammaproteobacteria,1X5DC@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria containing a pentein-type domain - - - - - - - - - - - - Amidinotransf GDHHQS3_k127_86271_5 311402.Avi_1475 1.614e-10 62.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,4BA2M@82115|Rhizobiaceae 28211|Alphaproteobacteria S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox GDHHQS3_k127_86271_0 1163407.UU7_14755 5.96e-84 288.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1X3TW@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N GDHHQS3_k127_86271_3 1123073.KB899241_gene3521 2.423e-29 125.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1X6P1@135614|Xanthomonadales 135614|Xanthomonadales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX GDHHQS3_k127_86271_1 1279015.KB908456_gene1636 3.249e-57 206.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1Y4ET@135624|Aeromonadales 135624|Aeromonadales K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 GDHHQS3_k127_86271_4 1121013.P873_11175 4.187e-13 73.0 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria,1X8YH@135614|Xanthomonadales 135614|Xanthomonadales H ThiS family - - - - - - - - - - - - ThiS GDHHQS3_k127_86271_2 84531.JMTZ01000019_gene3992 3.599e-51 183.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1X4FP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG GDHHQS3_k127_8681868_2 313606.M23134_00438 1.782e-23 99.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.32,1.2.1.85 ko:K00128,ko:K10217 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220 M00038,M00135,M00569 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh GDHHQS3_k127_8681868_1 1278073.MYSTI_00938 2.289e-54 196.0 COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,438KW@68525|delta/epsilon subdivisions,2X3V9@28221|Deltaproteobacteria,2YX7P@29|Myxococcales 28221|Deltaproteobacteria J Endoribonuclease L-PSP - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP GDHHQS3_k127_8681868_0 1127673.GLIP_3524 7.958e-74 261.0 COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,1SYS3@1236|Gammaproteobacteria,4672R@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 GDHHQS3_k127_8688148_2 1163407.UU7_16617 2.646e-84 288.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GDHHQS3_k127_8688148_4 1384054.N790_03690 7.53e-17 83.0 COG5481@1|root,COG5481@2|Bacteria,1QB94@1224|Proteobacteria,1SHNI@1236|Gammaproteobacteria,1X84D@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 GDHHQS3_k127_8688148_1 1286106.MPL1_05037 1.136e-130 422.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales 72273|Thiotrichales D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 GDHHQS3_k127_8688148_0 631362.Thi970DRAFT_04690 3.091e-133 445.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP GDHHQS3_k127_8688148_3 1049564.TevJSym_as00390 1.336e-47 172.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM GDHHQS3_k127_8703617_7 1441629.PCH70_49770 1.165e-26 114.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1Z4RZ@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 GDHHQS3_k127_8703617_3 523791.Kkor_2300 1.019e-63 233.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XJ9V@135619|Oceanospirillales 135619|Oceanospirillales D peptidase - - - - - - - - - - - - Peptidase_M23 GDHHQS3_k127_8703617_0 1300345.LF41_1662 8.332e-196 623.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1X44Q@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N GDHHQS3_k127_8703617_6 1397528.Q671_03315 1.709e-27 119.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1XKHI@135619|Oceanospirillales 135619|Oceanospirillales P Sulfurtransferase - - - - - - - - - - - - Rhodanese GDHHQS3_k127_8703617_5 1211114.ALIP01000134_gene1596 1.248e-44 168.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1X65X@135614|Xanthomonadales 135614|Xanthomonadales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB GDHHQS3_k127_8703617_1 1045855.DSC_02130 1.479e-118 390.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales 135614|Xanthomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N GDHHQS3_k127_8703617_4 1001585.MDS_4574 1.27e-57 204.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1YFZM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase GDHHQS3_k127_8703617_2 1123073.KB899241_gene2359 6.363e-116 376.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN GDHHQS3_k127_8769678_0 1265505.ATUG01000002_gene1059 3.529e-133 454.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3 GDHHQS3_k127_8769678_1 1396418.BATQ01000049_gene417 2.815e-102 364.0 COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae 203494|Verrucomicrobiae T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 GDHHQS3_k127_8769678_2 1191523.MROS_2017 2.763e-19 91.0 COG0745@1|root,COG0745@2|Bacteria 1191523.MROS_2017|- T phosphorelay signal transduction system - - - - - - - - - - - - - GDHHQS3_k127_8810654_1 1265313.HRUBRA_02110 1.029e-32 136.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,1RY70@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 GDHHQS3_k127_8810654_0 1121374.KB891589_gene71 9.33e-109 363.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2BS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec GDHHQS3_k127_8830000_4 1230476.C207_01464 1.866e-12 68.0 COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,2UMFB@28211|Alphaproteobacteria,3K277@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SEC-C Motif Domain Protein - - - - - - - - - - - - - GDHHQS3_k127_8830000_5 95619.PM1_0203300 3.705e-09 65.0 2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,1SI3D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2845) - - - - - - - - - - - - DUF2845 GDHHQS3_k127_8830000_1 1122185.N792_05240 5.499e-69 240.0 COG3023@1|root,COG3023@2|Bacteria,1N0IM@1224|Proteobacteria,1S959@1236|Gammaproteobacteria,1X602@135614|Xanthomonadales 135614|Xanthomonadales V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 GDHHQS3_k127_8830000_0 247634.GPB2148_2252 8.799e-118 388.0 COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1J4BZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2333 GDHHQS3_k127_8830000_2 1123073.KB899241_gene2996 5.661e-51 186.0 COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S27W@1236|Gammaproteobacteria,1X6CI@135614|Xanthomonadales 135614|Xanthomonadales K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 GDHHQS3_k127_8830000_3 1211114.ALIP01000088_gene766 4.208e-47 170.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1X4N0@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM GDHHQS3_k127_8854389_9 706587.Desti_4725 4.531e-21 103.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gumK - 2.4.1.264 ko:K07011,ko:K13659 - - R09732 RC00005,RC00049 ko00000,ko01000,ko01003 - GT70 - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2 GDHHQS3_k127_8854389_4 211165.AJLN01000104_gene6579 2.026e-51 196.0 COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria,1JHI8@1189|Stigonemataceae 1117|Cyanobacteria M Glycosyl transferases group 1 - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_8854389_2 861299.J421_0868 1.68e-99 351.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups epsN - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GDHHQS3_k127_8854389_5 351160.RCIX216 5.643e-49 186.0 COG1134@1|root,arCOG00210@2157|Archaea,2Y2WI@28890|Euryarchaeota,2NAPC@224756|Methanomicrobia 224756|Methanomicrobia E ATPases associated with a variety of cellular activities - - - ko:K09691 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC_tran,Wzt_C GDHHQS3_k127_8854389_8 1232443.BAIA02000155_gene1826 2.727e-24 113.0 COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,269GF@186813|unclassified Clostridiales 186801|Clostridia GM ABC-2 type transporter - - - ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 - - ABC2_membrane GDHHQS3_k127_8854389_10 1267535.KB906767_gene5425 5.687e-10 70.0 COG1216@1|root,COG1216@2|Bacteria,3Y6DH@57723|Acidobacteria 57723|Acidobacteria M Glycosyltransferase like family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 GDHHQS3_k127_8854389_7 118166.JH976537_gene3933 6.595e-32 136.0 COG1215@1|root,COG1215@2|Bacteria,1FZZM@1117|Cyanobacteria,1H716@1150|Oscillatoriales 1117|Cyanobacteria M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GDHHQS3_k127_8854389_11 1121405.dsmv_2746 8.033e-08 64.0 COG0438@1|root,COG0438@2|Bacteria,1R7ZD@1224|Proteobacteria,42PZN@68525|delta/epsilon subdivisions,2WKSY@28221|Deltaproteobacteria,2MIJW@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - - GDHHQS3_k127_8854389_1 187272.Mlg_1761 2.31e-112 376.0 COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales 135613|Chromatiales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin GDHHQS3_k127_8854389_0 1123057.P872_11785 1.895e-167 546.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia 976|Bacteroidetes E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 GDHHQS3_k127_8875116_2 1211114.ALIP01000135_gene1122 6.929e-56 204.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria,1X5QD@135614|Xanthomonadales 135614|Xanthomonadales I acetyltransferase plsC1 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GDHHQS3_k127_8875116_0 1300345.LF41_2144 4.294e-100 337.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1X3GG@135614|Xanthomonadales 135614|Xanthomonadales S hydrolase of the alpha beta-hydrolase fold - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 GDHHQS3_k127_8875116_1 1123368.AUIS01000007_gene2734 1.441e-69 249.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,2NCDI@225057|Acidithiobacillales 225057|Acidithiobacillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 GDHHQS3_k127_8875116_3 1485544.JQKP01000001_gene1165 2.52e-18 84.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales 28216|Betaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrD4 - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran GDHHQS3_k127_8897056_2 435908.IDSA_11890 1.112e-32 145.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,2QFKS@267893|Idiomarinaceae 1236|Gammaproteobacteria M POTRA domain TamA domain 1 tamA - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 GDHHQS3_k127_8897056_1 1249627.D779_3720 2.347e-93 317.0 COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1WXBJ@135613|Chromatiales 135613|Chromatiales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B GDHHQS3_k127_8897056_0 1210884.HG799471_gene14692 1.975e-191 608.0 COG3069@1|root,COG3069@2|Bacteria,2IZPM@203682|Planctomycetes 203682|Planctomycetes C C4-dicarboxylate transmembrane transporter activity - - - ko:K03326 - - - - ko00000,ko02000 2.A.61.1 - - DcuC GDHHQS3_k127_8897056_3 1122137.AQXF01000003_gene1871 5.796e-18 86.0 COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,2VFH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 GDHHQS3_k127_8910030_2 187272.Mlg_0761 2.318e-54 193.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1WYCP@135613|Chromatiales 135613|Chromatiales K PFAM regulatory protein, MerR - - - - - - - - - - - - MerR_1 GDHHQS3_k127_8910030_3 1123256.KB907928_gene2115 6.297e-41 153.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,1X6Y2@135614|Xanthomonadales 135614|Xanthomonadales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ihfA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding GDHHQS3_k127_8910030_0 1385515.N791_14185 7.762e-238 758.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1X313@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind GDHHQS3_k127_8910030_1 666685.R2APBS1_1051 5.372e-118 382.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1X40X@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d GDHHQS3_k127_993043_5 1234364.AMSF01000095_gene2535 6.27e-65 228.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1X3MH@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf GDHHQS3_k127_993043_8 1042377.AFPJ01000029_gene526 9.703e-06 55.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 GDHHQS3_k127_993043_0 572477.Alvin_1217 9.672e-263 822.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1WXRW@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit GDHHQS3_k127_993043_1 1209072.ALBT01000011_gene3204 1.134e-152 488.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1FGZ3@10|Cellvibrio 1236|Gammaproteobacteria J tRNA synthetases class I (W and Y) trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b GDHHQS3_k127_993043_7 1449049.JONW01000006_gene2762 2.721e-10 69.0 COG2867@1|root,COG2867@2|Bacteria 2|Bacteria I negative regulation of translational initiation - - - - - - - - - - - - Polyketide_cyc,Polyketide_cyc2,START GDHHQS3_k127_993043_3 1442599.JAAN01000033_gene1614 9.557e-118 385.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1X3SU@135614|Xanthomonadales 135614|Xanthomonadales K Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate GDHHQS3_k127_993043_2 1121015.N789_05525 1.412e-146 470.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X393@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP GDHHQS3_k127_993043_4 243365.CV_0813 9.718e-117 391.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KPZP@206351|Neisseriales 206351|Neisseriales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase GDHHQS3_k127_993043_6 935863.AWZR01000002_gene1181 3.434e-37 145.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1X43G@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulator cysB - - - - - - - - - - - HTH_1,LysR_substrate ## 2984 queries scanned ## Total time (seconds): 59.0571665763855 ## Rate: 50.53 q/s