## Fri Nov 15 10:52:53 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin4/GDHHQS_3_bin.93.fa -m mmseqs --itype genome -o GDHHQS_3_bin.93 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/GDHHQS_3_bin.93 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GDHHQS3_k127_1033202_1	926569.ANT_05310	2.107e-88	303.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS3_k127_1033202_0	926569.ANT_05300	1.328e-267	836.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS3_k127_1033202_2	926569.ANT_05280	1.703e-66	235.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS3_k127_1033202_3	926569.ANT_05250	2.44e-46	176.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
GDHHQS3_k127_1033202_4	926569.ANT_05240	1.995e-38	152.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GDHHQS3_k127_1106236_2	926569.ANT_26980	1.938e-78	266.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
GDHHQS3_k127_1106236_1	926569.ANT_26970	2.998e-82	283.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
GDHHQS3_k127_1106236_9	234267.Acid_6209	5.328e-30	125.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GDHHQS3_k127_1106236_3	330214.NIDE3889	1.204e-71	248.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
GDHHQS3_k127_1106236_10	234267.Acid_6208	7.746e-27	128.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_B
GDHHQS3_k127_1106236_11	1125863.JAFN01000001_gene2793	3.667e-24	119.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS3_k127_1106236_0	926569.ANT_21940	2.065e-181	583.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
GDHHQS3_k127_1106236_12	1348908.KI518608_gene3432	5.066e-12	70.0	COG0640@1|root,COG0640@2|Bacteria,1TVW1@1239|Firmicutes,4I4FZ@91061|Bacilli,1ZIYD@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS3_k127_1106236_6	1121920.AUAU01000012_gene2648	2.117e-50	199.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
GDHHQS3_k127_1106236_5	523841.HFX_2210	1.026e-59	215.0	COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,23TXG@183963|Halobacteria	183963|Halobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	hmoA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11
GDHHQS3_k127_1106236_14	452637.Oter_2583	2.593e-08	66.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS3_k127_1106236_4	485913.Krac_6669	1.038e-63	224.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_1106236_7	290397.Adeh_1998	1.36e-42	174.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
GDHHQS3_k127_1106236_13	926569.ANT_26960	6.912e-09	59.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1145145_3	240302.BN982_02690	8.605e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3NESW@45667|Halobacillus	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS3_k127_1145145_2	926569.ANT_31640	1.115e-77	265.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_1145145_0	926569.ANT_31630	1.817e-202	638.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_1145145_1	926569.ANT_31620	1.317e-130	424.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_1158867_7	1444309.JAQG01000092_gene1331	3.332e-14	78.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,26XCY@186822|Paenibacillaceae	91061|Bacilli	P	Chromate transporter	srpC_2	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS3_k127_1158867_5	593105.S7A_13485	2.799e-33	136.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,3W0K9@53335|Pantoea	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GDHHQS3_k127_1158867_2	926569.ANT_00660	2.76e-61	225.0	COG0287@1|root,COG0287@2|Bacteria,2G9BH@200795|Chloroflexi	200795|Chloroflexi	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GDHHQS3_k127_1158867_6	926569.ANT_00650	6.633e-28	116.0	COG2827@1|root,COG2827@2|Bacteria,2G9H6@200795|Chloroflexi	200795|Chloroflexi	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS3_k127_1158867_0	926569.ANT_00640	5.294e-89	296.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GDHHQS3_k127_1158867_4	1227360.C176_00815	1.963e-40	159.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,4HTH7@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1158867_3	926569.ANT_06250	4.407e-50	183.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
GDHHQS3_k127_1158867_1	926569.ANT_00510	8.48e-75	258.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GDHHQS3_k127_1160693_13	760568.Desku_0322	2.417e-29	133.0	COG4924@1|root,COG4924@2|Bacteria,1V0BQ@1239|Firmicutes,24DRK@186801|Clostridia,2625E@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
GDHHQS3_k127_1160693_3	760568.Desku_0321	2.468e-136	474.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,2630X@186807|Peptococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
GDHHQS3_k127_1160693_14	760568.Desku_0320	3.805e-22	104.0	2A8HA@1|root,30XJD@2|Bacteria,1UPU3@1239|Firmicutes,25HP8@186801|Clostridia,26728@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
GDHHQS3_k127_1160693_10	457570.Nther_0773	7.682e-44	179.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1160693_17	457429.ABJI02000040_gene3876	4.945e-06	53.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
GDHHQS3_k127_1160693_5	1094508.Tsac_0588	5.512e-84	297.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
GDHHQS3_k127_1160693_16	1382356.JQMP01000001_gene1270	1.079e-08	58.0	COG1925@1|root,COG1925@2|Bacteria,2GBTB@200795|Chloroflexi,27ZBR@189775|Thermomicrobia	189775|Thermomicrobia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_1160693_12	1304874.JAFY01000002_gene11	1.451e-37	147.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PEP-utilisers_N,PEP-utilizers,PTS-HPr,PTS_EIIA_2
GDHHQS3_k127_1160693_11	300852.55771488	1.372e-43	167.0	COG0036@1|root,COG0036@2|Bacteria,1WI8K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_1160693_6	1232447.BAHW02000058_gene3406	1.754e-76	269.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,267PI@186813|unclassified Clostridiales	186801|Clostridia	E	M42 glutamyl aminopeptidase	-	-	-	ko:K20609	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M42
GDHHQS3_k127_1160693_0	1304874.JAFY01000002_gene12	6.916e-182	577.0	COG3775@1|root,COG3775@2|Bacteria	2|Bacteria	G	galactitol transmembrane transporter activity	sgcC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015791,GO:0015796,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090584	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
GDHHQS3_k127_1160693_15	1211115.ALIQ01000067_gene3452	2.264e-18	91.0	COG3414@1|root,COG3414@2|Bacteria,1N061@1224|Proteobacteria,2VGXN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.200	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_IIB
GDHHQS3_k127_1160693_4	526218.Sterm_3749	1.889e-122	399.0	COG0434@1|root,COG0434@2|Bacteria	2|Bacteria	S	BtpA family	sgcQ	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
GDHHQS3_k127_1160693_8	926550.CLDAP_27090	8.442e-63	224.0	COG1349@1|root,COG1349@2|Bacteria,2G8GY@200795|Chloroflexi	200795|Chloroflexi	K	Helix-turn-helix type 11 domain protein	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GDHHQS3_k127_1160693_1	926569.ANT_15960	1.284e-177	563.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
GDHHQS3_k127_1160693_9	926569.ANT_15970	1.596e-48	178.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_1160693_7	926569.ANT_15980	1.325e-68	246.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1160693_2	1047013.AQSP01000144_gene895	2.49e-155	501.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS3_k127_1178788_1	926569.ANT_21060	2.697e-98	331.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_1178788_3	316274.Haur_2664	7.186e-27	122.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GDHHQS3_k127_1178788_0	926569.ANT_21050	8.386e-292	908.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
GDHHQS3_k127_1180499_7	926567.TheveDRAFT_0773	2.283e-05	49.0	COG0223@1|root,COG0223@2|Bacteria,3TAJ5@508458|Synergistetes	508458|Synergistetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS3_k127_1180499_4	290512.Paes_2197	3.549e-65	227.0	COG1592@1|root,COG1592@2|Bacteria,1FE9N@1090|Chlorobi	1090|Chlorobi	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GDHHQS3_k127_1180499_0	653733.Selin_2559	0.0	1209.0	COG0376@1|root,COG0376@2|Bacteria	2|Bacteria	P	catalase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
GDHHQS3_k127_1180499_3	697282.Mettu_2925	4.454e-180	569.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1XF21@135618|Methylococcales	135618|Methylococcales	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GDHHQS3_k127_1180499_5	497321.C664_07233	1.805e-24	106.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VU78@28216|Betaproteobacteria,2KX1D@206389|Rhodocyclales	206389|Rhodocyclales	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GDHHQS3_k127_1180499_2	595494.Tola_1002	2.432e-237	741.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1S0YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
GDHHQS3_k127_1180499_6	867845.KI911784_gene13	7.401e-15	79.0	COG0640@1|root,COG0640@2|Bacteria,2GB64@200795|Chloroflexi,377ES@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS3_k127_1180499_1	926569.ANT_27610	1.199e-257	801.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_1180628_3	485913.Krac_11859	2.161e-57	207.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_1180628_0	926569.ANT_12730	5.873e-165	529.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_1180628_6	1077974.GOEFS_006_00180	7.38e-11	68.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4GACS@85026|Gordoniaceae	201174|Actinobacteria	T	Universal stress protein family	uspA1	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_1180628_4	926569.ANT_29910	1.115e-50	189.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi	200795|Chloroflexi	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTPase_1
GDHHQS3_k127_1180628_5	1123024.AUII01000021_gene6	3.186e-15	90.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GDHHQS3_k127_1180628_1	926569.ANT_29620	7.458e-112	391.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GDHHQS3_k127_1180628_2	926569.ANT_27540	1.012e-108	361.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS3_k127_1183710_2	926569.ANT_09460	6.633e-70	245.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GDHHQS3_k127_1183710_0	926569.ANT_03560	2.336e-205	647.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GDHHQS3_k127_1183710_1	926569.ANT_29500	5.247e-72	248.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_1183710_5	1521187.JPIM01000032_gene1982	5.133e-08	63.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_1183710_3	926569.ANT_29480	1.431e-36	142.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_1223369_3	1521187.JPIM01000001_gene834	2.837e-88	305.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_1223369_0	383372.Rcas_4054	2.602e-197	623.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1223369_1	926569.ANT_23180	1.563e-129	426.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GDHHQS3_k127_1223369_2	926569.ANT_23190	2.501e-105	351.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GDHHQS3_k127_1227911_4	754027.HMPREF9554_01554	1.536e-21	96.0	COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes	203691|Spirochaetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS3_k127_1227911_0	1089553.Tph_c26530	3.339e-165	535.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GDHHQS3_k127_1227911_2	1336243.JAEA01000013_gene3290	5.846e-59	216.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,1JRHR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GDHHQS3_k127_1227911_3	926569.ANT_05910	1.492e-53	195.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GDHHQS3_k127_1227911_1	926569.ANT_05900	4.519e-98	324.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1251559_0	635013.TherJR_2241	1.106e-298	932.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_1251559_35	1487923.DP73_11295	2.657e-06	52.0	2EPM3@1|root,33H7R@2|Bacteria,1VN2P@1239|Firmicutes,24WDX@186801|Clostridia,26384@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1251559_12	926569.ANT_30130	3.682e-68	244.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS3_k127_1251559_29	1349820.M707_22385	8.094e-13	77.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,1WA5E@1268|Micrococcaceae	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_1251559_6	926569.ANT_23190	7.123e-117	389.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GDHHQS3_k127_1251559_20	926569.ANT_19420	9.196e-39	160.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GDHHQS3_k127_1251559_36	1448860.BBJO01000024_gene3096	3.109e-06	56.0	arCOG01916@1|root,arCOG01916@2157|Archaea,2XXSB@28890|Euryarchaeota,23W7I@183963|Halobacteria	183963|Halobacteria	S	Zn-ribbon RNA-binding protein with a function in translation	-	-	-	-	-	-	-	-	-	-	-	-	DZR,RHH_1,zinc_ribbon_2
GDHHQS3_k127_1251559_23	926569.ANT_19460	1.639e-32	133.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GDHHQS3_k127_1251559_2	926550.CLDAP_40030	6.933e-168	550.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS3_k127_1251559_19	926550.CLDAP_40040	5.219e-42	160.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
GDHHQS3_k127_1251559_42	697303.Thewi_2667	0.0009052	47.0	COG3350@1|root,COG3350@2|Bacteria,1VKZJ@1239|Firmicutes,24VQV@186801|Clostridia,42HIA@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam yhs	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_1251559_4	1276756.AUEX01000008_gene3277	4.805e-158	504.0	COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria	1224|Proteobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
GDHHQS3_k127_1251559_39	926569.ANT_24830	1.734e-05	49.0	COG2230@1|root,COG2230@2|Bacteria,2G8QA@200795|Chloroflexi	200795|Chloroflexi	H	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GDHHQS3_k127_1251559_1	365044.Pnap_4524	1.215e-273	865.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VMF6@28216|Betaproteobacteria,4ABS8@80864|Comamonadaceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_1251559_21	926550.CLDAP_28250	1.145e-37	145.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GDHHQS3_k127_1251559_14	1123377.AUIV01000013_gene2385	5.831e-61	220.0	COG1073@1|root,COG1073@2|Bacteria,1QFTH@1224|Proteobacteria,1TD3S@1236|Gammaproteobacteria,1XA29@135614|Xanthomonadales	135614|Xanthomonadales	S	Serine hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_1251559_27	1121423.JONT01000007_gene533	2.059e-20	98.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24C8S@186801|Clostridia,2615Y@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_1251559_38	1123377.AUIV01000006_gene1544	1.387e-05	56.0	2ASN4@1|root,31I2V@2|Bacteria,1QFS0@1224|Proteobacteria,1TD1J@1236|Gammaproteobacteria,1X9WY@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1251559_24	1305732.JAGG01000001_gene1178	1.216e-28	124.0	COG4478@1|root,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,4FS2J@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
GDHHQS3_k127_1251559_26	153721.MYP_861	1.148e-24	108.0	28JUV@1|root,30VEM@2|Bacteria,4NY80@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1251559_30	83219.PM02_17820	1.794e-09	64.0	28JUV@1|root,2Z9JV@2|Bacteria,1R9BS@1224|Proteobacteria,2TQV7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1251559_37	1306174.JODP01000004_gene1159	5.08e-06	54.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria	201174|Actinobacteria	E	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_1251559_16	1227484.C471_16132	6.172e-59	223.0	COG0402@1|root,arCOG00695@2157|Archaea,2XV7Z@28890|Euryarchaeota,23TQA@183963|Halobacteria	183963|Halobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_1251559_9	926560.KE387025_gene3980	3.33e-99	335.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1251559_10	926560.KE387025_gene3981	2.043e-96	329.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1251559_5	926560.KE387025_gene3982	1.391e-118	392.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1251559_15	926550.CLDAP_04380	5.037e-60	220.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS3_k127_1251559_18	1123284.KB899044_gene613	3.015e-47	176.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,4HGC7@91061|Bacilli,26PJP@186821|Sporolactobacillaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_1251559_40	292459.STH2810	0.000176	44.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_1251559_7	926569.ANT_15760	1.84e-114	378.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_1251559_17	1041139.KB902697_gene2668	3.744e-48	180.0	COG1018@1|root,COG1018@2|Bacteria,1Q8DS@1224|Proteobacteria,2VEKC@28211|Alphaproteobacteria,4BJCK@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1251559_25	926569.ANT_01150	1.314e-25	114.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS3_k127_1251559_8	926569.ANT_26570	1.149e-111	372.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_1251559_11	926569.ANT_26560	4.221e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1251559_13	926569.ANT_26550	1.84e-65	231.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
GDHHQS3_k127_1251559_22	1196322.A370_04755	3.962e-35	139.0	COG0666@1|root,COG0666@2|Bacteria,1VD0K@1239|Firmicutes,24X0T@186801|Clostridia	186801|Clostridia	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
GDHHQS3_k127_1251559_3	195250.CM001776_gene1918	8.483e-165	536.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1GCX6@1117|Cyanobacteria,1GZFG@1129|Synechococcus	1117|Cyanobacteria	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GDHHQS3_k127_1251559_28	868595.Desca_1376	5.211e-15	80.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS3_k127_126093_7	926569.ANT_14720	1.275e-12	68.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_126093_6	411471.SUBVAR_04595	5.689e-20	104.0	COG1807@1|root,COG1807@2|Bacteria,1V1A0@1239|Firmicutes,24DT2@186801|Clostridia,3WK77@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_126093_0	926569.ANT_14730	8.328e-134	437.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_126093_3	926569.ANT_22300	1.205e-64	240.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
GDHHQS3_k127_126093_4	926569.ANT_22310	7.685e-37	146.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GDHHQS3_k127_126093_2	926569.ANT_22320	1.386e-96	327.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GDHHQS3_k127_126093_1	1121918.ARWE01000001_gene3548	5.983e-100	333.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,42R1Q@68525|delta/epsilon subdivisions,2WN15@28221|Deltaproteobacteria,43TCU@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_126093_5	671143.DAMO_0400	3.175e-27	115.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
GDHHQS3_k127_1290582_0	926569.ANT_04130	1.543e-147	486.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GDHHQS3_k127_1290582_3	926550.CLDAP_16010	2.661e-50	191.0	COG2267@1|root,COG2267@2|Bacteria,2G6W2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_1290582_2	926569.ANT_04120	1.649e-69	241.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GDHHQS3_k127_1290582_1	926569.ANT_23050	3.52e-107	358.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
GDHHQS3_k127_1290582_4	1117108.PAALTS15_21638	1.451e-05	55.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
GDHHQS3_k127_1290582_5	1128421.JAGA01000002_gene246	0.0003695	46.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,Transglut_core,VCBS
GDHHQS3_k127_12977_3	247633.GP2143_03938	7.759e-50	187.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1JARK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_12977_1	316274.Haur_3061	3.74e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,2GAJP@200795|Chloroflexi,37683@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_12977_2	326427.Cagg_2708	6.875e-61	224.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_12977_5	926550.CLDAP_15590	6.308e-14	81.0	2FKQZ@1|root,30TRG@2|Bacteria,2G9KN@200795|Chloroflexi	200795|Chloroflexi	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
GDHHQS3_k127_12977_6	1410630.JNKP01000006_gene199	1.071e-11	69.0	2EFXE@1|root,339PN@2|Bacteria,1VPU7@1239|Firmicutes,24VU8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_12977_0	926569.ANT_05230	1.44e-223	702.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
GDHHQS3_k127_1309435_5	926569.ANT_31760	5.24e-88	296.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
GDHHQS3_k127_1309435_4	926569.ANT_02410	1.164e-92	315.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pelF	-	-	ko:K21011,ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
GDHHQS3_k127_1309435_7	765420.OSCT_0663	1.502e-56	215.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1309435_1	926569.ANT_23150	8.78e-122	400.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_1309435_6	1382356.JQMP01000003_gene2120	5.501e-76	275.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
GDHHQS3_k127_1309435_12	525904.Tter_0431	4.328e-05	55.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF1581,DUF1583,PD40,Peptidase_C14,PrcB_C,SLH,WD40
GDHHQS3_k127_1309435_3	398767.Glov_0718	3.78e-98	327.0	COG3527@1|root,COG3527@2|Bacteria,1MWDZ@1224|Proteobacteria,42R9C@68525|delta/epsilon subdivisions,2WN1P@28221|Deltaproteobacteria,43UXZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
GDHHQS3_k127_1309435_9	504728.K649_00235	1.566e-36	146.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
GDHHQS3_k127_1309435_8	1306174.JODP01000004_gene781	1.814e-39	158.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GDHHQS3_k127_1309435_0	526227.Mesil_1248	8.466e-124	415.0	COG3119@1|root,COG3119@2|Bacteria,1WM9P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
GDHHQS3_k127_1309435_2	927677.ALVU02000001_gene3793	3.624e-117	397.0	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1FZWU@1117|Cyanobacteria,1H61N@1142|Synechocystis	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
GDHHQS3_k127_1309435_11	1380391.JIAS01000020_gene1408	1.141e-29	121.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VFPM@28211|Alphaproteobacteria,2JWWJ@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_1311776_23	313628.LNTAR_21780	8.889e-14	72.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
GDHHQS3_k127_1311776_8	316274.Haur_2046	7.497e-88	305.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
GDHHQS3_k127_1311776_17	926550.CLDAP_22540	1.366e-37	146.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_1311776_15	1521187.JPIM01000134_gene1339	4.518e-50	184.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi,3770T@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_1311776_25	926569.ANT_15080	5.444e-13	78.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_1311776_19	926569.ANT_28120	1.612e-29	130.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
GDHHQS3_k127_1311776_14	926569.ANT_18550	1.211e-59	217.0	COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GDHHQS3_k127_1311776_20	926569.ANT_18570	8.322e-28	121.0	COG0400@1|root,COG0400@2|Bacteria,2G7EK@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS3_k127_1311776_5	926569.ANT_18500	4.033e-95	323.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS3_k127_1311776_6	926569.ANT_18490	2.663e-94	314.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS3_k127_1311776_7	926569.ANT_18470	4.723e-89	304.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS3_k127_1311776_11	926569.ANT_18460	7.032e-69	242.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GDHHQS3_k127_1311776_10	926569.ANT_18450	3.082e-76	262.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi	200795|Chloroflexi	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GDHHQS3_k127_1311776_22	926569.ANT_18440	2.601e-16	81.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GDHHQS3_k127_1311776_18	926569.ANT_18430	1.356e-32	128.0	COG1872@1|root,COG1872@2|Bacteria,2G7H4@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GDHHQS3_k127_1311776_1	926569.ANT_14290	3.577e-174	575.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
GDHHQS3_k127_1311776_4	926569.ANT_16190	2.939e-127	415.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GDHHQS3_k127_1311776_16	530564.Psta_0724	3.237e-47	179.0	COG1994@1|root,COG1994@2|Bacteria,2J0CK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS3_k127_1311776_3	926569.ANT_16180	1.423e-134	436.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS3_k127_1311776_0	926569.ANT_16170	1.643e-214	672.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GDHHQS3_k127_1311776_26	867845.KI911784_gene2206	6.354e-07	60.0	COG1716@1|root,COG3391@1|root,COG4733@1|root,COG1716@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1,3.2.1.78	ko:K01218,ko:K12132	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26	-	FHA,NHL,PA14,fn3
GDHHQS3_k127_1311776_9	926569.ANT_03800	2.725e-85	293.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GDHHQS3_k127_1311776_21	1280706.AUJE01000004_gene2432	4.278e-18	96.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4H30N@909932|Negativicutes	909932|Negativicutes	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS3_k127_1311776_12	926569.ANT_03810	2.575e-62	229.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
GDHHQS3_k127_1311776_13	926569.ANT_03610	5.636e-61	220.0	COG1708@1|root,COG1708@2|Bacteria,2G7IZ@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4111)	-	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
GDHHQS3_k127_1311776_2	479434.Sthe_1490	3.48e-138	456.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_1315682_40	926569.ANT_19020	6.926e-16	77.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi	200795|Chloroflexi	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_1315682_25	926569.ANT_10030	1.256e-52	186.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GDHHQS3_k127_1315682_17	867845.KI911784_gene938	4.128e-65	229.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GDHHQS3_k127_1315682_12	926569.ANT_10050	2.634e-78	267.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GDHHQS3_k127_1315682_36	926569.ANT_10060	1.313e-30	123.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
GDHHQS3_k127_1315682_4	926569.ANT_10070	3.758e-146	466.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
GDHHQS3_k127_1315682_30	926569.ANT_10080	3.678e-43	158.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
GDHHQS3_k127_1315682_32	926569.ANT_10090	7.931e-39	147.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
GDHHQS3_k127_1315682_8	926569.ANT_10100	2e-94	316.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
GDHHQS3_k127_1315682_18	926569.ANT_10110	1.067e-64	223.0	COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi	200795|Chloroflexi	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
GDHHQS3_k127_1315682_43	926569.ANT_10120	3.17e-10	64.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
GDHHQS3_k127_1315682_37	926569.ANT_10130	3.389e-30	123.0	COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
GDHHQS3_k127_1315682_19	926569.ANT_10140	5.178e-64	220.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi	200795|Chloroflexi	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
GDHHQS3_k127_1315682_31	926569.ANT_10150	5.261e-42	156.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi	200795|Chloroflexi	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
GDHHQS3_k127_1315682_10	926569.ANT_10160	3.322e-87	291.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
GDHHQS3_k127_1315682_38	926569.ANT_10170	2.335e-29	117.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
GDHHQS3_k127_1315682_21	926569.ANT_10180	1.149e-61	214.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
GDHHQS3_k127_1315682_14	926569.ANT_10190	1.03e-71	247.0	COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GDHHQS3_k127_1315682_33	1158318.ATXC01000001_gene1258	1.148e-38	147.0	COG0256@1|root,COG0256@2|Bacteria,2G476@200783|Aquificae	200783|Aquificae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
GDHHQS3_k127_1315682_15	926569.ANT_10210	1.615e-70	243.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GDHHQS3_k127_1315682_39	485913.Krac_12510	1.277e-17	84.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
GDHHQS3_k127_1315682_23	926569.ANT_10230	6.181e-58	205.0	COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GDHHQS3_k127_1315682_2	926569.ANT_10240	1.474e-164	529.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GDHHQS3_k127_1315682_11	926569.ANT_10250	7.589e-82	277.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GDHHQS3_k127_1315682_6	926569.ANT_10260	2.27e-115	377.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_1315682_42	161156.JQKW01000006_gene1057	2.146e-12	70.0	COG0257@1|root,COG0257@2|Bacteria,2GI5G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GDHHQS3_k127_1315682_22	926569.ANT_10280	4.162e-59	206.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GDHHQS3_k127_1315682_20	926569.ANT_10290	8.358e-63	217.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GDHHQS3_k127_1315682_9	926569.ANT_10300	3.111e-89	298.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GDHHQS3_k127_1315682_3	926569.ANT_10310	8.134e-156	497.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GDHHQS3_k127_1315682_26	926569.ANT_10320	1.551e-50	183.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GDHHQS3_k127_1315682_13	926569.ANT_10330	2.369e-74	257.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GDHHQS3_k127_1315682_27	525904.Tter_0745	9.854e-50	181.0	COG0102@1|root,COG0102@2|Bacteria,2NPCI@2323|unclassified Bacteria	2|Bacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GDHHQS3_k127_1315682_29	926569.ANT_10350	2.503e-45	167.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GDHHQS3_k127_1315682_7	926569.ANT_10380	3.577e-104	350.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
GDHHQS3_k127_1315682_1	110319.CF8_2443	2.553e-291	923.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,2GJEW@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M4,Peptidase_M4_C
GDHHQS3_k127_1315682_34	316274.Haur_1185	2.325e-35	140.0	COG0454@1|root,COG0456@2|Bacteria,2G9MN@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_1315682_5	189753.AXAS01000017_gene3061	9.33e-141	466.0	COG1622@1|root,COG2132@1|root,COG3474@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,COG3474@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,3JV1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
GDHHQS3_k127_1315682_28	926569.ANT_15330	1.692e-45	173.0	COG0664@1|root,COG0664@2|Bacteria,2G70E@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_1315682_35	926569.ANT_12610	9.968e-33	129.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GDHHQS3_k127_1315682_41	926569.ANT_12600	9.893e-16	78.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
GDHHQS3_k127_1315682_0	926569.ANT_12590	0.0	1116.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_1315682_24	926569.ANT_12580	2.269e-56	201.0	2EQH8@1|root,33I38@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1315682_16	926569.ANT_26810	1.039e-69	244.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
GDHHQS3_k127_1331603_4	909663.KI867150_gene1871	3.593e-116	378.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MQRM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
GDHHQS3_k127_1331603_8	1449126.JQKL01000002_gene1553	3.097e-27	116.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
GDHHQS3_k127_1331603_12	394503.Ccel_3365	5.674e-15	78.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GDHHQS3_k127_1331603_2	926569.ANT_17860	1.221e-234	751.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GDHHQS3_k127_1331603_9	926569.ANT_17870	7.349e-25	106.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi	200795|Chloroflexi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
GDHHQS3_k127_1331603_3	926569.ANT_17880	7.067e-162	516.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
GDHHQS3_k127_1331603_5	635013.TherJR_1303	3.919e-115	382.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,260QH@186807|Peptococcaceae	186801|Clostridia	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_1331603_10	1540221.JQNI01000002_gene1262	3.141e-19	91.0	COG2388@1|root,COG2388@2|Bacteria,1WMZW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
GDHHQS3_k127_1331603_7	457570.Nther_2759	1.747e-50	192.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_1331603_1	926569.ANT_25010	2.818e-254	788.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
GDHHQS3_k127_1331603_0	926569.ANT_24980	2.633e-297	936.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GDHHQS3_k127_1331603_6	1382306.JNIM01000001_gene3886	1.102e-103	348.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GDHHQS3_k127_1349687_31	1121441.AUCX01000018_gene1493	2.219e-15	76.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_1349687_1	926569.ANT_10010	0.0	1042.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_1349687_21	926569.ANT_10000	8.121e-59	207.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GDHHQS3_k127_1349687_19	926569.ANT_09990	1.352e-71	243.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GDHHQS3_k127_1349687_0	926569.ANT_09980	0.0	2010.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GDHHQS3_k127_1349687_34	935836.JAEL01000201_gene4586	9.573e-05	49.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1349687_26	1173021.ALWA01000016_gene2104	1.444e-34	155.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G46J@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS3_k127_1349687_13	926569.ANT_03450	3.065e-93	347.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS3_k127_1349687_6	926550.CLDAP_22390	1.453e-135	443.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GDHHQS3_k127_1349687_17	926550.CLDAP_29040	4.185e-76	265.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GDHHQS3_k127_1349687_16	926569.ANT_09940	7.723e-79	265.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GDHHQS3_k127_1349687_22	518766.Rmar_1910	1.06e-45	175.0	COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS3_k127_1349687_9	926569.ANT_09930	2.196e-116	391.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
GDHHQS3_k127_1349687_14	765420.OSCT_0605	1.204e-89	304.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi,374U5@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1349687_18	926569.ANT_09910	3.086e-75	261.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_1349687_20	926569.ANT_09900	1.166e-61	218.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_1349687_2	926569.ANT_09890	2.483e-210	677.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS3_k127_1349687_15	926569.ANT_09880	3.097e-79	276.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
GDHHQS3_k127_1349687_3	926569.ANT_09870	1.668e-183	594.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GDHHQS3_k127_1349687_24	926569.ANT_09860	1.067e-42	162.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GDHHQS3_k127_1349687_25	926569.ANT_09850	1.046e-37	150.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1349687_10	926569.ANT_09840	1.085e-114	376.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_1349687_12	926569.ANT_09820	1.806e-96	334.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G97C@200795|Chloroflexi	200795|Chloroflexi	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_1349687_8	926569.ANT_09810	1.478e-126	413.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GDHHQS3_k127_1349687_28	1492738.FEM21_17350	1.805e-24	106.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia,2NWDS@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_1349687_7	926569.ANT_09800	2.855e-128	416.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_1349687_23	926569.ANT_09790	4.808e-43	164.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GDHHQS3_k127_1349687_11	1191523.MROS_0930	3.687e-101	341.0	COG0787@1|root,COG0787@2|Bacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GDHHQS3_k127_1349687_29	43759.JNWK01000046_gene2823	9.907e-21	97.0	COG0454@1|root,COG1670@1|root,COG0456@2|Bacteria,COG1670@2|Bacteria,2IHSI@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_1349687_5	1128421.JAGA01000004_gene2611	3.361e-144	473.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GDHHQS3_k127_1349687_32	686340.Metal_3032	1.615e-10	65.0	COG4691@1|root,COG4691@2|Bacteria,1N09T@1224|Proteobacteria,1SH18@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
GDHHQS3_k127_1349687_30	13035.Dacsa_1483	2.516e-20	94.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GDHHQS3_k127_1349687_4	266117.Rxyl_0743	3.978e-148	476.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS3_k127_1360454_3	1499967.BAYZ01000009_gene5290	8.153e-180	571.0	COG1155@1|root,COG1155@2|Bacteria,2NNYK@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
GDHHQS3_k127_1360454_2	1499967.BAYZ01000009_gene5291	2.331e-189	602.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS3_k127_1360454_16	309803.CTN_0922	3.182e-36	148.0	COG1394@1|root,COG1394@2|Bacteria,2GD6P@200918|Thermotogae	200918|Thermotogae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
GDHHQS3_k127_1360454_8	1144275.COCOR_04108	5.409e-65	229.0	COG2085@1|root,COG2085@2|Bacteria,1NF95@1224|Proteobacteria,4380B@68525|delta/epsilon subdivisions,2X3AC@28221|Deltaproteobacteria,2YURK@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS3_k127_1360454_1	926569.ANT_10550	1.331e-203	645.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_1360454_12	485913.Krac_0932	1.303e-55	200.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_1360454_9	269797.Mbar_A1683	2.182e-63	228.0	COG0604@1|root,arCOG01458@2157|Archaea,2XURG@28890|Euryarchaeota,2N9N6@224756|Methanomicrobia	224756|Methanomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS3_k127_1360454_5	926569.ANT_03400	4.056e-110	369.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_1360454_17	365044.Pnap_0159	3.612e-25	109.0	2E75R@1|root,331PX@2|Bacteria,1NAGT@1224|Proteobacteria,2W4DV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1360454_0	926569.ANT_10570	4.199e-304	949.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GDHHQS3_k127_1360454_18	926569.ANT_10580	3.768e-25	109.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GDHHQS3_k127_1360454_11	697284.ERIC2_c09080	4.42e-58	211.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,4HFXH@91061|Bacilli,26S9D@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS3_k127_1360454_10	697284.ERIC2_c09070	1.271e-61	222.0	COG4587@1|root,COG4587@2|Bacteria,1UZ3Y@1239|Firmicutes,4HFHM@91061|Bacilli,26V8Z@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS3_k127_1360454_14	485913.Krac_5382	8.383e-46	176.0	2DM3D@1|root,31J5I@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
GDHHQS3_k127_1360454_4	1408422.JHYF01000013_gene500	1.252e-112	380.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,36F1A@31979|Clostridiaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1360454_7	1128421.JAGA01000003_gene3146	1.419e-84	287.0	COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria	2|Bacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS3_k127_1360454_19	479435.Kfla_2617	2.654e-18	89.0	COG4308@1|root,COG4308@2|Bacteria,2IJ55@201174|Actinobacteria	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS3_k127_1360454_13	485913.Krac_1641	2.547e-51	188.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_1360454_6	485913.Krac_7710	7.857e-101	331.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_1360454_20	386456.JQKN01000001_gene2088	0.0005948	42.0	COG0251@1|root,arCOG01630@2157|Archaea	2157|Archaea	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_1385168_2	179408.Osc7112_4771	9.316e-183	585.0	COG2114@1|root,COG2114@2|Bacteria,1G335@1117|Cyanobacteria,1H8VG@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_1385168_9	867845.KI911784_gene751	2.777e-16	80.0	28VCT@1|root,2ZHFH@2|Bacteria,2GB88@200795|Chloroflexi,377J8@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1385168_5	56107.Cylst_1905	9.542e-89	299.0	COG0455@1|root,COG0455@2|Bacteria,1G1EJ@1117|Cyanobacteria,1HQDQ@1161|Nostocales	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
GDHHQS3_k127_1385168_7	1140.Synpcc7942_1814	1.156e-21	104.0	COG0664@1|root,COG3850@1|root,COG0664@2|Bacteria,COG3850@2|Bacteria,1GEZE@1117|Cyanobacteria,1H27Y@1129|Synechococcus	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GDHHQS3_k127_1385168_11	138119.DSY4459	7.308e-10	70.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,266DG@186807|Peptococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GDHHQS3_k127_1385168_6	1499967.BAYZ01000090_gene4936	8.308e-35	151.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_1385168_8	1122919.KB905603_gene4708	1.826e-19	96.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4INIS@91061|Bacilli,26UFN@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_1385168_3	765420.OSCT_2174	4.841e-114	373.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
GDHHQS3_k127_1385168_1	316274.Haur_0810	7.019e-199	641.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,3756T@32061|Chloroflexia	32061|Chloroflexia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GDHHQS3_k127_1385168_4	457425.XNR_0019	1.147e-106	359.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
GDHHQS3_k127_1385168_0	926569.ANT_01580	2.361e-281	885.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS3_k127_1398713_13	479434.Sthe_2302	1.999e-48	188.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS3_k127_1398713_4	926569.ANT_08920	3.38e-115	379.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_1398713_6	926569.ANT_08910	1.314e-98	339.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
GDHHQS3_k127_1398713_12	926569.ANT_02700	3.492e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GDHHQS3_k127_1398713_8	929703.KE386491_gene2365	1.753e-64	229.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,47PEW@768503|Cytophagia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_1398713_11	877455.Metbo_1144	9.251e-53	209.0	COG0784@1|root,arCOG06712@1|root,arCOG06537@2157|Archaea,arCOG06712@2157|Archaea,2XWYJ@28890|Euryarchaeota	28890|Euryarchaeota	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_4,PAS_9,PadR,Response_reg
GDHHQS3_k127_1398713_14	243164.DET1064	2.384e-45	186.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8KS@200795|Chloroflexi,34CTW@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_9
GDHHQS3_k127_1398713_9	311424.DhcVS_934	1.759e-63	224.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,34CR4@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_1398713_15	1132855.KB913035_gene720	1.078e-35	158.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VMSZ@28216|Betaproteobacteria,2KMS6@206350|Nitrosomonadales	206350|Nitrosomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GGDEF,PAS_9
GDHHQS3_k127_1398713_10	457570.Nther_2059	4.226e-54	217.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
GDHHQS3_k127_1398713_7	929703.KE386491_gene2187	1.039e-76	265.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,47PJY@768503|Cytophagia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
GDHHQS3_k127_1398713_3	926569.ANT_13490	8.861e-120	396.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS3_k127_1398713_5	1321778.HMPREF1982_02748	2.143e-111	376.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,2686Y@186813|unclassified Clostridiales	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GDHHQS3_k127_1398713_2	926569.ANT_04660	7.469e-157	499.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GDHHQS3_k127_1398713_19	240302.BN982_00337	9.189e-17	93.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3NDHD@45667|Halobacillus	91061|Bacilli	S	AI-2E family transporter	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_1398713_1	926569.ANT_04670	1.948e-173	553.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_1398713_16	504472.Slin_1330	7.21e-26	108.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160,Phage_integrase
GDHHQS3_k127_1398713_18	395961.Cyan7425_0492	7.071e-24	104.0	COG1396@1|root,COG1396@2|Bacteria,1GGP9@1117|Cyanobacteria	1117|Cyanobacteria	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_1398713_17	980584.AFPB01000113_gene3031	4.576e-24	103.0	arCOG06613@1|root,2Z7VT@2|Bacteria,4NFYT@976|Bacteroidetes,1I71S@117743|Flavobacteriia	976|Bacteroidetes	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
GDHHQS3_k127_1398713_20	397290.C810_00801	1.956e-14	74.0	2BHUU@1|root,32BYI@2|Bacteria,1UJXD@1239|Firmicutes,25FDA@186801|Clostridia,27Q6J@186928|unclassified Lachnospiraceae	186801|Clostridia	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
GDHHQS3_k127_1398713_0	926569.ANT_14810	1.633e-272	850.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GDHHQS3_k127_1431583_11	1449058.JQKT01000007_gene1960	9.271e-13	72.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431583_10	479435.Kfla_2275	9.29e-20	94.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DR0C@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431583_3	765420.OSCT_1468	4.136e-110	368.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_1431583_14	246197.MXAN_7185	1.081e-05	57.0	2D28H@1|root,32TC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431583_12	443143.GM18_0409	6.11e-08	65.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.78	ko:K01218,ko:K13276	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH26	-	CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3
GDHHQS3_k127_1431583_15	935567.JAES01000008_gene1989	0.0006452	48.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431583_4	536227.CcarbDRAFT_4777	1.838e-99	330.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
GDHHQS3_k127_1431583_2	926569.ANT_18650	1.876e-127	414.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_1431583_7	926569.ANT_18660	9.572e-68	238.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
GDHHQS3_k127_1431583_1	926569.ANT_18670	1.805e-135	449.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
GDHHQS3_k127_1431583_13	203119.Cthe_2709	7.233e-08	62.0	2DBSS@1|root,2ZATI@2|Bacteria,1V481@1239|Firmicutes,24C13@186801|Clostridia,3WJTS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
GDHHQS3_k127_1431583_0	926550.CLDAP_07480	6.745e-136	443.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_1431583_9	1379270.AUXF01000001_gene2369	1.975e-21	100.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_1431583_5	926569.ANT_11510	4.076e-80	285.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431583_8	926569.ANT_11540	2.331e-60	228.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_1431583_6	926569.ANT_11570	2.405e-75	277.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GDHHQS3_k127_1431649_16	211165.AJLN01000098_gene5105	9.264e-18	83.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,1JMCI@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_1431649_14	118168.MC7420_2828	1.785e-31	125.0	COG1669@1|root,COG1669@2|Bacteria,1G8U6@1117|Cyanobacteria,1HCKC@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_1431649_17	866536.Belba_2531	4.009e-15	80.0	COG2361@1|root,COG2361@2|Bacteria,4NV8D@976|Bacteroidetes,47SBF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_1431649_0	926569.ANT_16840	0.0	1141.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GDHHQS3_k127_1431649_13	641526.ADIWIN_2870	2.601e-42	178.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1431649_20	926550.CLDAP_12150	1.147e-06	59.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1	ko:K12132,ko:K15539	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	SH3_3,SH3_4
GDHHQS3_k127_1431649_5	1444309.JAQG01000164_gene1837	1.815e-140	464.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
GDHHQS3_k127_1431649_6	926569.ANT_14740	1.04e-130	426.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GDHHQS3_k127_1431649_8	765420.OSCT_2364	5.217e-79	269.0	COG0586@1|root,COG0586@2|Bacteria,2G79V@200795|Chloroflexi	200795|Chloroflexi	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
GDHHQS3_k127_1431649_19	323850.Shew_0750	4.064e-12	72.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria,2QCRS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GDHHQS3_k127_1431649_1	1173028.ANKO01000042_gene858	4.439e-317	992.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS3_k127_1431649_9	926569.ANT_15050	3.476e-60	219.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GDHHQS3_k127_1431649_21	926569.ANT_15060	2.197e-06	54.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GDHHQS3_k127_1431649_11	926569.ANT_14610	7.934e-53	190.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GDHHQS3_k127_1431649_15	926569.ANT_14620	4.474e-31	128.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GDHHQS3_k127_1431649_7	556261.HMPREF0240_00427	1.763e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36EGR@31979|Clostridiaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_1431649_12	926569.ANT_20710	9.505e-48	180.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
GDHHQS3_k127_1431649_4	926569.ANT_20700	1.661e-173	558.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GDHHQS3_k127_1431649_2	1122222.AXWR01000018_gene2629	6.133e-247	774.0	COG0286@1|root,COG0286@2|Bacteria,1WI3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	HsdM N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HsdM_N,N6_Mtase
GDHHQS3_k127_1431649_10	402777.KB235903_gene2254	2.165e-55	198.0	COG1943@1|root,COG1943@2|Bacteria,1G79U@1117|Cyanobacteria,1HBVQ@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS3_k127_1515894_1	316274.Haur_1681	1.491e-95	323.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi,3759N@32061|Chloroflexia	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS3_k127_1515894_0	497964.CfE428DRAFT_5350	5.964e-103	352.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GDHHQS3_k127_1523622_5	926569.ANT_13960	3.22e-171	552.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GDHHQS3_k127_1523622_15	1125863.JAFN01000001_gene577	3.415e-51	194.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS3_k127_1523622_10	926569.ANT_13900	3.242e-103	348.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_13900|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1523622_11	926569.ANT_13890	4.255e-102	336.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_1523622_22	326427.Cagg_3209	5.256e-18	96.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
GDHHQS3_k127_1523622_21	1232437.KL662077_gene1836	4.201e-18	88.0	2EU69@1|root,33MNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1523622_3	926569.ANT_13870	1.711e-184	586.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS3_k127_1523622_17	926569.ANT_13860	1.329e-42	164.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GDHHQS3_k127_1523622_20	926569.ANT_13850	6.705e-26	113.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_13850|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1523622_16	926569.ANT_13840	6.901e-45	174.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_1523622_24	765420.OSCT_2813	0.000189	51.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
GDHHQS3_k127_1523622_13	1449126.JQKL01000016_gene2859	1.118e-70	250.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
GDHHQS3_k127_1523622_19	1382356.JQMP01000003_gene1647	2.379e-35	145.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS3_k127_1523622_12	926569.ANT_08740	1.162e-84	286.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_1523622_18	266117.Rxyl_2810	4.696e-38	166.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_1523622_0	1047013.AQSP01000070_gene34	6.321e-202	674.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y
GDHHQS3_k127_1523622_4	545276.KB898724_gene2041	3.033e-173	573.0	COG0747@1|root,COG3889@1|root,COG0747@2|Bacteria,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_1523622_8	926550.CLDAP_11030	1.116e-133	437.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_1523622_6	926550.CLDAP_11020	1.129e-149	485.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_1523622_9	1121939.L861_22650	1.083e-127	415.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1S1BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_1523622_23	1035308.AQYY01000001_gene3509	5.456e-07	59.0	COG2318@1|root,COG2318@2|Bacteria,1V3EE@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
GDHHQS3_k127_1523622_7	926550.CLDAP_11000	2.4e-142	459.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_1523622_14	1333998.M2A_0597	1.797e-66	239.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,4BQ8Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GDHHQS3_k127_1523622_1	926569.ANT_30330	1.21e-195	635.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
GDHHQS3_k127_1523622_2	926569.ANT_30340	3.205e-191	605.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_1529959_4	1535422.ND16A_3796	3.861e-06	51.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,2Q6EE@267889|Colwelliaceae	1236|Gammaproteobacteria	J	N2,N2-dimethylguanosine tRNA methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_1529959_0	485913.Krac_8270	2.501e-189	609.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_1529959_1	1501230.ET33_37205	4.125e-181	583.0	COG1132@1|root,COG1132@2|Bacteria,1TRCZ@1239|Firmicutes,4HCDT@91061|Bacilli,26RQU@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_1529959_2	1163617.SCD_n02069	1.279e-148	479.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_1529959_3	760192.Halhy_2350	1.421e-24	104.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,1IT43@117747|Sphingobacteriia	976|Bacteroidetes	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GDHHQS3_k127_153230_8	316274.Haur_3935	1.077e-24	109.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_153230_9	1033743.CAES01000066_gene4211	7.223e-15	80.0	2FC4Z@1|root,3448W@2|Bacteria,1U2X0@1239|Firmicutes,4ICJY@91061|Bacilli,272JJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_153230_5	1144275.COCOR_05704	1.294e-36	150.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GDHHQS3_k127_153230_7	1034943.BN1094_01655	9.484e-27	114.0	2ERG8@1|root,33J1S@2|Bacteria,1NMXE@1224|Proteobacteria,1SVEJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
GDHHQS3_k127_153230_6	351160.RCIX701	1.147e-32	130.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_153230_4	635013.TherJR_0758	2.661e-50	191.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
GDHHQS3_k127_153230_0	292459.STH384	9.057e-100	334.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia	186801|Clostridia	H	PFAM extracellular solute-binding protein family 1	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
GDHHQS3_k127_153230_1	1382356.JQMP01000003_gene1639	1.817e-90	304.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
GDHHQS3_k127_153230_2	671143.DAMO_1144	8.78e-76	259.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
GDHHQS3_k127_153230_3	1121430.JMLG01000007_gene2536	2.602e-60	217.0	COG3842@1|root,COG3842@2|Bacteria,1V5RM@1239|Firmicutes,24IMD@186801|Clostridia,261V9@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_1537816_2	1265503.KB905164_gene1785	1.327e-42	159.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,2Q8CE@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_1537816_1	661478.OP10G_2200	4.128e-89	308.0	2DQGC@1|root,336PP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
GDHHQS3_k127_1537816_0	1538295.JY96_06170	1.099e-126	415.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VNXC@28216|Betaproteobacteria,1KMBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.148	ko:K07222,ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3,SnoaL_2
GDHHQS3_k127_1537816_3	696747.NIES39_Q00900	0.0003504	43.0	COG3335@1|root,COG3335@2|Bacteria,1GAQA@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS3_k127_1537876_10	926569.ANT_11990	4.43e-28	117.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS3_k127_1537876_4	1869.MB27_20185	3.207e-78	273.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4D9FN@85008|Micromonosporales	201174|Actinobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS3_k127_1537876_5	675635.Psed_0413	4.966e-76	267.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GDHHQS3_k127_1537876_2	365046.Rta_32000	2.237e-103	344.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_1537876_1	1121272.KB903249_gene1588	1.598e-145	467.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DCFG@85008|Micromonosporales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_1537876_9	1172188.KB911820_gene2389	1.102e-54	202.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria,4FH1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
GDHHQS3_k127_1537876_6	926569.ANT_19570	1.211e-69	255.0	COG1807@1|root,COG1807@2|Bacteria,2G79E@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS3_k127_1537876_7	926569.ANT_19510	1.21e-60	237.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
GDHHQS3_k127_1537876_14	1173028.ANKO01000112_gene4858	1.647e-06	56.0	2DR31@1|root,339YG@2|Bacteria,1GAVI@1117|Cyanobacteria,1HDY2@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
GDHHQS3_k127_1537876_12	1128427.KB904821_gene4604	1.727e-12	72.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1HCUI@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GDHHQS3_k127_1537876_13	395961.Cyan7425_2954	6.227e-12	76.0	COG1493@1|root,COG1493@2|Bacteria,1G5K9@1117|Cyanobacteria	1117|Cyanobacteria	T	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1537876_3	1487953.JMKF01000041_gene3159	2.464e-78	285.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1H8UK@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_1537876_8	395493.BegalDRAFT_1833	1.11e-55	227.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
GDHHQS3_k127_1537876_0	1541065.JRFE01000014_gene1505	1.687e-234	815.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G8F1@1117|Cyanobacteria,3VMVS@52604|Pleurocapsales	1117|Cyanobacteria	M	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
GDHHQS3_k127_1537876_11	1001585.MDS_1417	1.327e-14	85.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NTP_transf_5
GDHHQS3_k127_154121_6	768706.Desor_1586	2.712e-26	117.0	2EIQA@1|root,33CFR@2|Bacteria,1W559@1239|Firmicutes,254YN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_154121_1	926569.ANT_23020	6.846e-152	501.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_154121_2	926569.ANT_23030	4.325e-96	326.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
GDHHQS3_k127_154121_0	926569.ANT_01520	1.47e-182	577.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GDHHQS3_k127_154121_5	1121936.AUHI01000006_gene1919	8.536e-29	119.0	2E363@1|root,32Y5Y@2|Bacteria,1W3CU@1239|Firmicutes,4HZRV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_154121_7	926569.ANT_02810	6.83e-16	81.0	2ESUF@1|root,33KCV@2|Bacteria,2G9MJ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_154121_3	926569.ANT_02820	1.734e-60	224.0	COG0681@1|root,COG2200@1|root,COG0681@2|Bacteria,COG2200@2|Bacteria,2G85E@200795|Chloroflexi	200795|Chloroflexi	U	Family of unknown function (DUF5305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5305,Peptidase_S24
GDHHQS3_k127_155221_1	1121422.AUMW01000006_gene704	8.843e-166	530.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,26029@186807|Peptococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
GDHHQS3_k127_155221_2	383372.Rcas_1705	3.34e-110	363.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_155221_0	1121324.CLIT_8c01210	9.237e-169	550.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_155221_3	357808.RoseRS_3926	2.968e-106	351.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_1576301_8	1166018.FAES_4235	1.019e-26	128.0	COG1413@1|root,COG2905@1|root,COG1413@2|Bacteria,COG2905@2|Bacteria,4PKPI@976|Bacteroidetes,47YF3@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
GDHHQS3_k127_1576301_0	118161.KB235922_gene3038	4.716e-139	453.0	COG2081@1|root,COG2081@2|Bacteria,1FZZ1@1117|Cyanobacteria,3VIXX@52604|Pleurocapsales	1117|Cyanobacteria	S	flavoprotein, HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GDHHQS3_k127_1576301_7	1461580.CCAS010000015_gene1869	3.581e-41	161.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GDHHQS3_k127_1576301_1	1293054.HSACCH_00979	2.621e-129	426.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,249WU@186801|Clostridia,3WB1M@53433|Halanaerobiales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_1576301_3	1293054.HSACCH_00980	5.121e-101	338.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WBQ6@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_1576301_4	1293054.HSACCH_00981	3.038e-81	280.0	COG0395@1|root,COG0395@2|Bacteria,1V3Y9@1239|Firmicutes,25C5H@186801|Clostridia,3WBP0@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_1576301_5	1267533.KB906735_gene4567	1.568e-59	226.0	COG1940@1|root,COG1940@2|Bacteria,3Y6YN@57723|Acidobacteria,2JKMS@204432|Acidobacteriia	204432|Acidobacteriia	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_1576301_6	204669.Acid345_0004	7.343e-53	199.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS3_k127_1576301_2	926569.ANT_01810	2.186e-106	351.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_157754_6	221288.JH992901_gene4609	4.391e-51	186.0	COG0563@1|root,COG0563@2|Bacteria,1G696@1117|Cyanobacteria,1JKMG@1189|Stigonemataceae	1117|Cyanobacteria	F	COG0563 Adenylate kinase and related	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PduV-EutP,SKI
GDHHQS3_k127_157754_1	1172188.KB911823_gene524	1.884e-140	459.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria,4FE6Q@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
GDHHQS3_k127_157754_4	765420.OSCT_3196	7.59e-66	250.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_157754_7	941449.dsx2_1285	1.187e-39	153.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2MB6D@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_157754_5	1499967.BAYZ01000095_gene4130	2.653e-59	213.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	pfs	-	3.2.2.1,3.2.2.9,4.1.99.14	ko:K01239,ko:K01243,ko:K03716	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_157754_2	926569.ANT_16530	1.873e-127	420.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_157754_3	552811.Dehly_1197	2.316e-103	351.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GDHHQS3_k127_157754_0	926569.ANT_04080	5.627e-273	851.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
GDHHQS3_k127_157754_8	330214.NIDE0792	5.611e-11	63.0	COG1399@1|root,COG1399@2|Bacteria,3J0UQ@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS3_k127_1584827_19	1382356.JQMP01000001_gene1035	7.062e-05	45.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_1584827_16	234267.Acid_4775	6.606e-13	83.0	COG1361@1|root,COG1649@1|root,COG1361@2|Bacteria,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Glyco_hydro_42M,PKD,SLH,WG_beta_rep
GDHHQS3_k127_1584827_0	1386089.N865_11030	1.941e-252	812.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4FFZJ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
GDHHQS3_k127_1584827_11	1007105.PT7_0932	5.742e-36	141.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,2VUU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
GDHHQS3_k127_1584827_12	867845.KI911784_gene226	2.482e-33	137.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_1584827_6	765420.OSCT_2137	6.029e-104	351.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1584827_8	765420.OSCT_2138	2.01e-84	295.0	COG4591@1|root,COG4591@2|Bacteria,2G7ZF@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GDHHQS3_k127_1584827_7	765420.OSCT_2139	1.425e-94	315.0	COG1136@1|root,COG1136@2|Bacteria,2G7XA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_1584827_14	926550.CLDAP_36980	8.83e-28	123.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS3_k127_1584827_13	926550.CLDAP_36980	7.28e-28	124.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS3_k127_1584827_5	658086.HMPREF0994_03756	5.467e-106	359.0	COG1486@1|root,COG1486@2|Bacteria,1V6E5@1239|Firmicutes,24KU5@186801|Clostridia	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS3_k127_1584827_9	1242864.D187_001151	2.275e-71	253.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_1584827_1	1144275.COCOR_02904	1.657e-126	420.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,42Y39@68525|delta/epsilon subdivisions,2WSYZ@28221|Deltaproteobacteria,2YV2T@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GDHHQS3_k127_1584827_15	269800.Tfu_1426	2.169e-21	109.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1584827_17	1173264.KI913949_gene683	3.481e-10	71.0	28MCN@1|root,2ZAQR@2|Bacteria,1G1C5@1117|Cyanobacteria,1H8NJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1584827_3	1128421.JAGA01000002_gene694	6.236e-107	357.0	COG1092@1|root,COG1092@2|Bacteria	2|Bacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_1584827_10	926569.ANT_23300	1.278e-40	155.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS3_k127_1584827_4	926569.ANT_23310	1.937e-106	353.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GDHHQS3_k127_1584827_2	926569.ANT_23330	2.557e-120	403.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_1606699_5	1232410.KI421421_gene3301	5.038e-36	139.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2WSYR@28221|Deltaproteobacteria,43VCK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1606699_2	269799.Gmet_1792	4.656e-56	201.0	2B0BZ@1|root,31SP3@2|Bacteria,1RM1T@1224|Proteobacteria,42RVA@68525|delta/epsilon subdivisions,2WR20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1606699_9	468556.AQYG01000051_gene2286	0.0001746	48.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4GA38@85026|Gordoniaceae	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
GDHHQS3_k127_1606699_1	593750.Metfor_2818	9.389e-118	383.0	COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota	28890|Euryarchaeota	L	COG0863 DNA modification methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS3_k127_1606699_4	525904.Tter_1733	1.183e-39	156.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS3_k127_1606699_0	926569.ANT_06210	6.014e-204	653.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
GDHHQS3_k127_1606699_7	926569.ANT_06190	5.131e-28	113.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
GDHHQS3_k127_1606699_8	1173027.Mic7113_2574	0.0001452	49.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
GDHHQS3_k127_1646842_2	926569.ANT_03510	3.217e-73	251.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GDHHQS3_k127_1646842_1	926569.ANT_03500	1.037e-106	350.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS3_k127_1646842_3	926569.ANT_03490	1.238e-63	229.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS3_k127_1646842_0	926569.ANT_02050	6.719e-131	425.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi	200795|Chloroflexi	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
GDHHQS3_k127_1646842_4	797304.Natgr_1738	4.042e-07	59.0	COG1241@1|root,COG3780@1|root,arCOG03155@1|root,arCOG00439@2157|Archaea,arCOG03155@2157|Archaea,arCOG03156@2157|Archaea,2XT5D@28890|Euryarchaeota,23SII@183963|Halobacteria	183963|Halobacteria	L	ATPase involved in replication control, Cdc46 Mcm family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
GDHHQS3_k127_1646842_5	653733.Selin_0935	1.7e-06	50.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	repC	-	-	ko:K18996	-	-	-	-	ko00000,ko03032	-	-	-	RP-C,RP-C_C
GDHHQS3_k127_1656953_6	1122223.KB890697_gene1094	4.785e-06	48.0	COG0274@1|root,COG0274@2|Bacteria,1WI7Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS3_k127_1656953_5	1460634.JCM19037_2740	3.789e-13	74.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_1656953_2	1144275.COCOR_04930	1.455e-68	239.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria,434J2@68525|delta/epsilon subdivisions,2WYWB@28221|Deltaproteobacteria,2Z0SI@29|Myxococcales	28221|Deltaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_1656953_1	649638.Trad_0835	1.079e-136	441.0	COG0274@1|root,COG0274@2|Bacteria,1WI7Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS3_k127_1656953_4	118168.MC7420_7238	2.204e-14	75.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GDHHQS3_k127_1656953_3	221288.JH992901_gene1040	2.956e-38	149.0	COG2405@1|root,COG2405@2|Bacteria,1GJUX@1117|Cyanobacteria,1JJRP@1189|Stigonemataceae	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GDHHQS3_k127_1656953_0	45351.EDO38308	1.506e-137	442.0	COG1012@1|root,KOG2450@2759|Eukaryota,38CQ7@33154|Opisthokonta,3BH9X@33208|Metazoa	33208|Metazoa	C	aldehyde dehydrogenase (NAD) activity	aldh16a1	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_1676391_6	357808.RoseRS_3926	1.607e-51	187.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_1676391_0	1118054.CAGW01000101_gene4724	1.374e-191	608.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS3_k127_1676391_2	696369.KI912183_gene1935	1.369e-163	533.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_1676391_1	926569.ANT_01730	2.775e-172	549.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_1676391_12	138119.DSY0716	4.3e-05	53.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,263F4@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1676391_5	1223523.H340_12652	6.113e-58	218.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_1676391_9	1249480.B649_04605	5.652e-12	76.0	2BYFR@1|root,32R3B@2|Bacteria,1NSDG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1676391_10	400668.Mmwyl1_0056	1.995e-11	68.0	2ED2F@1|root,336ZC@2|Bacteria,1N758@1224|Proteobacteria,1SE5R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_1676391_8	870967.VIS19158_11633	4.297e-20	91.0	2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,1SADI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_1676391_4	926569.ANT_26870	3.455e-85	289.0	COG1432@1|root,COG1432@2|Bacteria,2G7FS@200795|Chloroflexi	200795|Chloroflexi	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GDHHQS3_k127_1676391_3	316274.Haur_1256	5.222e-98	337.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
GDHHQS3_k127_1676391_11	316274.Haur_1257	1.046e-05	56.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_7
GDHHQS3_k127_1676391_7	1173029.JH980292_gene2960	7.407e-47	183.0	COG0642@1|root,COG2205@2|Bacteria	1173029.JH980292_gene2960|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1683152_6	926569.ANT_01450	1.028e-70	242.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GDHHQS3_k127_1683152_12	41431.PCC8801_0803	5.183e-13	75.0	2E3GU@1|root,32YFI@2|Bacteria,1G9HI@1117|Cyanobacteria,3KIKQ@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1683152_1	926569.ANT_29060	1.362e-169	543.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
GDHHQS3_k127_1683152_8	926569.ANT_29050	1.783e-44	167.0	COG3005@1|root,COG3005@2|Bacteria,2G748@200795|Chloroflexi	200795|Chloroflexi	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
GDHHQS3_k127_1683152_7	485913.Krac_2500	2.717e-69	250.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
GDHHQS3_k127_1683152_0	926569.ANT_23160	4.157e-179	591.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
GDHHQS3_k127_1683152_5	926569.ANT_05520	2.054e-112	381.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS3_k127_1683152_3	926569.ANT_05530	1.709e-124	408.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS3_k127_1683152_10	485913.Krac_2293	4.633e-38	151.0	COG3340@1|root,COG3340@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GDHHQS3_k127_1683152_4	926569.ANT_05540	1.716e-121	398.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GDHHQS3_k127_1683152_11	926569.ANT_23620	2.71e-27	117.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GDHHQS3_k127_1683152_2	555079.Toce_0176	1.339e-135	445.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42EYY@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GDHHQS3_k127_1683152_9	317936.Nos7107_1874	3.785e-44	171.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_1683152_13	933262.AXAM01000051_gene2990	1.436e-05	49.0	COG3464@1|root,COG3464@2|Bacteria,1N5CJ@1224|Proteobacteria,43CJ2@68525|delta/epsilon subdivisions,2X7TC@28221|Deltaproteobacteria,2MPPB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_168410_0	1128421.JAGA01000004_gene2674	1.265e-205	645.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_168410_1	926550.CLDAP_06990	9.837e-172	556.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GDHHQS3_k127_168410_2	118168.MC7420_8015	4.325e-86	300.0	COG0395@1|root,COG0395@2|Bacteria,1G2TR@1117|Cyanobacteria,1H9ME@1150|Oscillatoriales	1117|Cyanobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GDHHQS3_k127_168410_3	1382306.JNIM01000001_gene1416	4.276e-78	272.0	COG1175@1|root,COG1175@2|Bacteria,2G7P7@200795|Chloroflexi	200795|Chloroflexi	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_168410_4	373903.Hore_14550	4.613e-63	233.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes	1239|Firmicutes	G	ABC transporter, substratebinding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
GDHHQS3_k127_168410_5	349521.HCH_06913	4.191e-15	76.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XJ8N@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_1686726_5	926569.ANT_31670	3.608e-59	209.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GDHHQS3_k127_1686726_3	97138.C820_01570	1.08e-61	229.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,36F75@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1,RecX
GDHHQS3_k127_1686726_7	926569.ANT_00680	5.736e-19	89.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
GDHHQS3_k127_1686726_1	316274.Haur_0048	5.97e-97	326.0	COG1235@1|root,COG1235@2|Bacteria,2G833@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GDHHQS3_k127_1686726_2	316274.Haur_0049	1.407e-67	237.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_1686726_6	926569.ANT_07030	1.602e-38	149.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GDHHQS3_k127_1686726_4	1286106.MPL1_08848	1.141e-60	218.0	2BH5I@1|root,32B6M@2|Bacteria,1RKHK@1224|Proteobacteria,1S7RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GDHHQS3_k127_1686726_0	926569.ANT_07040	1.017e-134	438.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
GDHHQS3_k127_1725338_2	1449063.JMLS01000007_gene3590	2.058e-13	83.0	COG2373@1|root,COG2373@2|Bacteria,1UMF4@1239|Firmicutes,4IUMG@91061|Bacilli,26W6D@186822|Paenibacillaceae	91061|Bacilli	S	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
GDHHQS3_k127_1725338_3	867903.ThesuDRAFT_00698	4.287e-06	59.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,3WDF8@538999|Clostridiales incertae sedis	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GDHHQS3_k127_1725338_1	469381.Dpep_0962	1.047e-52	191.0	COG0537@1|root,COG0537@2|Bacteria,3TB29@508458|Synergistetes	508458|Synergistetes	FG	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
GDHHQS3_k127_1725338_0	926569.ANT_26230	2.713e-55	197.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS3_k127_1727877_6	926569.ANT_05360	4.512e-68	235.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GDHHQS3_k127_1727877_7	316274.Haur_3781	9.916e-61	220.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_3781|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_1727877_2	316274.Haur_1250	2.972e-123	407.0	COG0477@1|root,COG2814@2|Bacteria,2G7YK@200795|Chloroflexi,376E9@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
GDHHQS3_k127_1727877_5	926569.ANT_28890	2.355e-74	264.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_1727877_4	926569.ANT_01460	1.402e-100	336.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GDHHQS3_k127_1727877_3	926569.ANT_02930	8.728e-108	356.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
GDHHQS3_k127_1727877_1	926569.ANT_19100	8.596e-133	436.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_1727877_9	926569.ANT_20640	4.807e-25	113.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
GDHHQS3_k127_1727877_0	926569.ANT_19090	4.445e-179	569.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_1727877_10	1041147.AUFB01000003_gene3813	7.044e-12	76.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_1727877_8	926569.ANT_22190	7.773e-37	152.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_181623_7	909663.KI867150_gene921	5.376e-42	159.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2MQAU@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
GDHHQS3_k127_181623_9	311424.DhcVS_1292	1.434e-41	167.0	COG1961@1|root,COG1961@2|Bacteria,2G8DZ@200795|Chloroflexi,34DGR@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_181623_6	330214.NIDE4178	5.748e-52	196.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS3_k127_181623_3	478741.JAFS01000001_gene1555	6.226e-71	249.0	28I4Y@1|root,2Z88D@2|Bacteria,46VRF@74201|Verrucomicrobia,37GMA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_181623_18	113355.CM001775_gene1870	4.101e-11	66.0	COG1724@1|root,COG1724@2|Bacteria,1G9H4@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_181623_14	933262.AXAM01000060_gene2895	1.73e-24	104.0	COG1598@1|root,COG1598@2|Bacteria,1NDHG@1224|Proteobacteria,432RS@68525|delta/epsilon subdivisions,2WXV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_181623_16	641149.HMPREF9016_01714	8.142e-23	102.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS3_k127_181623_1	1121382.JQKG01000080_gene894	1.652e-227	730.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_181623_2	1121382.JQKG01000080_gene895	3.301e-99	329.0	COG1136@1|root,COG1136@2|Bacteria,1WJ97@1297|Deinococcus-Thermus	2|Bacteria	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_181623_11	2002.JOEQ01000011_gene3842	1.235e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,2IMEB@201174|Actinobacteria,4ENRV@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS3_k127_181623_8	195103.CPF_2928	1.156e-41	156.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,36JKZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
GDHHQS3_k127_181623_13	641149.HMPREF9016_01714	1.29e-25	112.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS3_k127_181623_15	1343740.M271_17195	6.606e-23	107.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_181623_10	1170562.Cal6303_0400	4.326e-40	154.0	COG3385@1|root,COG3385@2|Bacteria,1G2T1@1117|Cyanobacteria,1HMX0@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_181623_19	306281.AJLK01000102_gene3400	4.084e-07	53.0	COG3385@1|root,COG3385@2|Bacteria,1G2T1@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_181623_5	211165.AJLN01000005_gene3823	1.21e-57	205.0	COG3385@1|root,COG3385@2|Bacteria,1GGJ4@1117|Cyanobacteria,1JJPW@1189|Stigonemataceae	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_181623_21	1174528.JH992893_gene5700	4.629e-06	49.0	COG3385@1|root,COG3385@2|Bacteria,1GGJ4@1117|Cyanobacteria,1JJPW@1189|Stigonemataceae	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_181623_17	324602.Caur_3419	1.071e-13	73.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi,375X2@32061|Chloroflexia	32061|Chloroflexia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_181623_20	765912.Thimo_2726	1.866e-06	52.0	COG1487@1|root,COG1487@2|Bacteria,1MZCD@1224|Proteobacteria,1S90W@1236|Gammaproteobacteria,1WZ6H@135613|Chromatiales	135613|Chromatiales	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_181623_0	926569.ANT_02690	1.294e-258	807.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
GDHHQS3_k127_1960898_1	926569.ANT_03330	4.641e-159	507.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_1960898_0	290397.Adeh_2070	7.864e-173	547.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_1960898_2	1242864.D187_003310	1.294e-130	422.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_1960898_3	926569.ANT_31030	1.623e-112	370.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GDHHQS3_k127_1960898_5	926569.ANT_31020	3.657e-79	269.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GDHHQS3_k127_1960898_4	926569.ANT_31010	8.65e-102	337.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_196808_13	118166.JH976537_gene2339	1.091e-05	48.0	COG5002@1|root,COG5002@2|Bacteria,1GQU9@1117|Cyanobacteria,1HH44@1150|Oscillatoriales	1117|Cyanobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,dCache_1
GDHHQS3_k127_196808_9	926569.ANT_26560	1.249e-94	314.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_196808_6	926569.ANT_26570	4.153e-101	341.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_196808_12	485913.Krac_9920	2.669e-19	90.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GDHHQS3_k127_196808_4	1121946.AUAX01000008_gene7362	4.99e-120	397.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4D9VG@85008|Micromonosporales	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
GDHHQS3_k127_196808_2	926569.ANT_18360	2.586e-144	466.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_196808_7	926569.ANT_18350	4.973e-98	335.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_196808_10	1089550.ATTH01000001_gene925	5.505e-94	317.0	COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,1FJDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GDHHQS3_k127_196808_3	926569.ANT_18090	2.68e-142	457.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_196808_0	926569.ANT_18100	5.749e-214	668.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
GDHHQS3_k127_196808_8	243365.CV_2022	5.793e-98	331.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria,2KQ2P@206351|Neisseriales	206351|Neisseriales	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GDHHQS3_k127_196808_1	1232410.KI421419_gene2455	2.02e-212	666.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,43UGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
GDHHQS3_k127_196808_5	383381.EH30_11975	3.691e-103	353.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2K07D@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GDHHQS3_k127_212805_2	1307761.L21SP2_3279	7.321e-31	128.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K03977,ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko03009	-	-	-	G3P_acyltransf
GDHHQS3_k127_212805_1	926569.ANT_29550	2.14e-68	242.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS3_k127_212805_0	926569.ANT_29560	1.738e-83	301.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
GDHHQS3_k127_2158427_1	1521187.JPIM01000021_gene179	3.187e-30	129.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2158427_2	929703.KE386491_gene499	4.403e-27	118.0	COG2020@1|root,COG2020@2|Bacteria,4NTXI@976|Bacteroidetes,47RFP@768503|Cytophagia	976|Bacteroidetes	O	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
GDHHQS3_k127_2158427_0	670487.Ocepr_1935	6.552e-250	797.0	COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_219707_10	260799.BAS0521	1.53e-28	124.0	COG0454@1|root,COG0456@2|Bacteria,1TU2N@1239|Firmicutes,4HH34@91061|Bacilli,1ZG8E@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_4
GDHHQS3_k127_219707_3	1121898.Q766_07240	1.992e-90	310.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2NSRJ@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_219707_4	357808.RoseRS_2229	4.442e-79	290.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_219707_11	68170.KL590484_gene7687	3.233e-20	99.0	2BX5G@1|root,33UAJ@2|Bacteria,2IIJA@201174|Actinobacteria,4E3J5@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_219707_5	644966.Tmar_2131	2.598e-60	217.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GDHHQS3_k127_219707_0	926569.ANT_06270	2.976e-220	690.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GDHHQS3_k127_219707_1	570952.ATVH01000011_gene229	4.636e-210	657.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2JPB4@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_219707_7	1192868.CAIU01000019_gene2649	1.729e-41	155.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria,43KUM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_219707_2	1128421.JAGA01000002_gene774	3.563e-151	498.0	COG1164@1|root,COG1164@2|Bacteria,2NNUU@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS3_k127_219707_8	926569.ANT_29860	2.327e-36	143.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2207047_4	745776.DGo_PC0169	7.572e-21	99.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_33
GDHHQS3_k127_2207047_5	227882.SAV_7570	4.559e-18	90.0	COG3415@1|root,COG3415@2|Bacteria,2IHIM@201174|Actinobacteria	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_29,HTH_32,HTH_33
GDHHQS3_k127_2207047_1	264462.Bd3476	6.223e-62	226.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2MTST@213481|Bdellovibrionales,2WQCC@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS3_k127_2207047_0	857087.Metme_3214	7.037e-80	282.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_2207047_2	357808.RoseRS_0197	1.562e-36	143.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,375U7@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS3_k127_2207047_3	383372.Rcas_0405	2.16e-30	134.0	COG3385@1|root,COG3385@2|Bacteria,2G8GC@200795|Chloroflexi,3768R@32061|Chloroflexia	32061|Chloroflexia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS3_k127_222856_3	926550.CLDAP_10690	9.848e-161	517.0	COG3552@1|root,COG4372@1|root,COG3552@2|Bacteria,COG4372@2|Bacteria,2G60I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
GDHHQS3_k127_222856_5	926550.CLDAP_10700	1.533e-145	467.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GDHHQS3_k127_222856_2	864051.BurJ1DRAFT_3434	2.503e-217	682.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,1KJ23@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS3_k127_222856_12	765420.OSCT_1686	3.145e-88	304.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_222856_7	765420.OSCT_1688	9.982e-119	391.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS3_k127_222856_19	398512.JQKC01000013_gene1399	1.228e-49	188.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_222856_13	926569.ANT_26780	9.891e-59	209.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_222856_6	926569.ANT_11560	4.232e-125	417.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_222856_16	479434.Sthe_1615	3.063e-55	201.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_222856_9	926569.ANT_11580	5.5e-110	364.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
GDHHQS3_k127_222856_14	926569.ANT_20630	3.683e-56	209.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GDHHQS3_k127_222856_4	926569.ANT_20640	7.222e-150	484.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
GDHHQS3_k127_222856_1	926569.ANT_20650	3.401e-230	720.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GDHHQS3_k127_222856_10	926569.ANT_20660	8.994e-104	346.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS3_k127_222856_8	926569.ANT_20670	4.728e-110	364.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GDHHQS3_k127_222856_18	926569.ANT_20680	5.576e-50	188.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi	200795|Chloroflexi	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GDHHQS3_k127_222856_15	926569.ANT_20690	2.248e-55	200.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
GDHHQS3_k127_222856_22	926569.ANT_20530	6.658e-42	163.0	COG0682@1|root,COG0682@2|Bacteria,2G8YW@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_222856_21	765420.OSCT_1795	2.053e-44	168.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_222856_0	926569.ANT_18080	2.514e-301	936.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GDHHQS3_k127_222856_17	926569.ANT_18070	2.218e-50	183.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GDHHQS3_k127_2246550_5	926569.ANT_11300	2.23e-132	432.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_2246550_28	926569.ANT_11310	1.009e-17	87.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GDHHQS3_k127_2246550_7	926569.ANT_11320	6.027e-129	421.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2246550_26	926569.ANT_22410	8.051e-26	109.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GDHHQS3_k127_2246550_20	926569.ANT_22420	1.128e-62	218.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS3_k127_2246550_25	926569.ANT_22430	1.794e-27	113.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GDHHQS3_k127_2246550_17	926569.ANT_22440	1.602e-87	306.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
GDHHQS3_k127_2246550_0	926569.ANT_22450	3.847e-318	1012.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GDHHQS3_k127_2246550_19	926569.ANT_22460	4.206e-78	268.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GDHHQS3_k127_2246550_12	926569.ANT_15400	2.79e-102	342.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_2246550_27	102125.Xen7305DRAFT_00020060	3.533e-21	112.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
GDHHQS3_k127_2246550_2	32057.KB217483_gene8946	4.237e-216	745.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GPZZ@1117|Cyanobacteria,1HJUW@1161|Nostocales	1117|Cyanobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VWA
GDHHQS3_k127_2246550_29	225849.swp_3374	2.466e-16	84.0	2DN6S@1|root,32VV5@2|Bacteria,1NFSJ@1224|Proteobacteria,1SCH4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4265)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4265
GDHHQS3_k127_2246550_21	1128421.JAGA01000002_gene1568	2.336e-47	186.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	wapA	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	NHL,PT-HINT,RHS_repeat
GDHHQS3_k127_2246550_11	1499967.BAYZ01000138_gene184	7.331e-116	379.0	28IMV@1|root,2Z8NA@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2246550_14	926569.ANT_20910	1.774e-98	330.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GDHHQS3_k127_2246550_3	1128421.JAGA01000002_gene879	1.153e-181	586.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_2246550_1	926569.ANT_20890	1.592e-282	881.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS3_k127_2246550_10	290397.Adeh_2106	3.494e-119	391.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GDHHQS3_k127_2246550_4	316274.Haur_1713	4.278e-164	529.0	COG2070@1|root,COG2070@2|Bacteria,2G78C@200795|Chloroflexi,376A6@32061|Chloroflexia	32061|Chloroflexia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
GDHHQS3_k127_2246550_18	880073.Calab_1950	1.182e-80	275.0	COG0708@1|root,COG0708@2|Bacteria,2NP5K@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
GDHHQS3_k127_2246550_22	926569.ANT_16430	5.54e-44	166.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2246550_24	926569.ANT_16420	1.221e-28	119.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GDHHQS3_k127_2246550_15	926569.ANT_16410	1.51e-94	328.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GDHHQS3_k127_2246550_32	9940.ENSOARP00000017324	1.406e-05	53.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BESA@33208|Metazoa,3CWK8@33213|Bilateria,488CJ@7711|Chordata,49309@7742|Vertebrata,3J3W5@40674|Mammalia,4J1G3@91561|Cetartiodactyla	33208|Metazoa	T	cAMP-dependent protein kinase type II-alpha regulatory	PRKAR2A	GO:0000166,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006469,GO:0006928,GO:0006935,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022607,GO:0023052,GO:0030030,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044853,GO:0045121,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050878,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051716,GO:0051726,GO:0060255,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097485,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902911,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
GDHHQS3_k127_2246550_6	1128421.JAGA01000002_gene1294	7.956e-132	433.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_2246550_8	1128421.JAGA01000002_gene1295	1.029e-126	415.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_2246550_9	311403.Arad_9357	4.027e-125	422.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,4B9PR@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2,DUF3382
GDHHQS3_k127_2246550_13	926550.CLDAP_29810	4.56e-100	333.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_2246550_16	1128421.JAGA01000002_gene1298	9.021e-94	312.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS3_k127_2246550_23	1173021.ALWA01000037_gene3519	5.533e-32	132.0	COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
GDHHQS3_k127_2284187_4	478741.JAFS01000002_gene633	3.472e-18	91.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,37GQ2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	NUDIX domain	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	NUDIX,RrnaAD
GDHHQS3_k127_2284187_1	1192034.CAP_1512	2.532e-130	426.0	COG0265@1|root,COG3287@1|root,COG0265@2|Bacteria,COG3287@2|Bacteria,1QUQH@1224|Proteobacteria,42Q8C@68525|delta/epsilon subdivisions,2WWR9@28221|Deltaproteobacteria,2YU1Q@29|Myxococcales	28221|Deltaproteobacteria	M	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS3_k127_2284187_0	926569.ANT_22520	3.315e-261	819.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GDHHQS3_k127_2284187_3	926569.ANT_22530	1.971e-49	184.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
GDHHQS3_k127_2284187_2	765420.OSCT_3068	4.997e-83	287.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GDHHQS3_k127_2284187_6	1395513.P343_06705	1.249e-06	61.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,1V0NC@1239|Firmicutes,4HNGM@91061|Bacilli	91061|Bacilli	GT	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
GDHHQS3_k127_2284187_5	748449.Halha_1337	4.814e-07	61.0	COG4254@1|root,COG4254@2|Bacteria,1UTZ3@1239|Firmicutes,254XU@186801|Clostridia,3WC5R@53433|Halanaerobiales	186801|Clostridia	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS3_k127_2290724_2	926550.CLDAP_38240	1.462e-94	312.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_2290724_5	1121481.AUAS01000006_gene588	1.046e-39	153.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GDHHQS3_k127_2290724_9	1521187.JPIM01000053_gene2946	1.519e-14	81.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_2290724_6	485913.Krac_7961	6.197e-38	164.0	COG0515@1|root,COG0515@2|Bacteria	485913.Krac_7961|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2290724_1	1395513.P343_13685	9.532e-107	355.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4IJPG@91061|Bacilli,26Q3J@186821|Sporolactobacillaceae	91061|Bacilli	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_2290724_8	1123073.KB899245_gene178	1.343e-18	92.0	COG1418@1|root,COG1418@2|Bacteria,1RGE5@1224|Proteobacteria,1SSYD@1236|Gammaproteobacteria,1XDF6@135614|Xanthomonadales	135614|Xanthomonadales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2290724_0	936053.I1C091	2.409e-154	502.0	COG4770@1|root,KOG0238@2759|Eukaryota,38B7N@33154|Opisthokonta,3NVGW@4751|Fungi,1GSZ7@112252|Fungi incertae sedis	4751|Fungi	C	Biotin carboxylase C-terminal domain	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS3_k127_2290724_7	926550.CLDAP_16280	3.21e-19	93.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS3_k127_2290724_4	926550.CLDAP_16300	1.228e-62	218.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
GDHHQS3_k127_2290724_3	1123389.ATXJ01000002_gene1468	4.701e-64	226.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
GDHHQS3_k127_22989_7	316274.Haur_3936	4.327e-49	179.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi,3780K@32061|Chloroflexia	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_22989_8	926550.CLDAP_07730	9.045e-43	164.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_10010	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_22989_1	926550.CLDAP_07720	2.555e-116	385.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GDHHQS3_k127_22989_10	1487923.DP73_01125	3.436e-33	144.0	COG0845@1|root,COG0845@2|Bacteria,1V0ZP@1239|Firmicutes,24DH2@186801|Clostridia,261UT@186807|Peptococcaceae	186801|Clostridia	M	PFAM HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_22989_2	926550.CLDAP_07700	3.055e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_22989_13	443218.AS9A_2168	1.596e-18	91.0	COG3832@1|root,COG3832@2|Bacteria,2GVS1@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_22989_3	926550.CLDAP_07690	2.374e-106	353.0	COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_22989_14	309799.DICTH_0496	4.616e-15	76.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspB	-	-	ko:K03970,ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF4097,PspB,PspC
GDHHQS3_k127_22989_6	1035308.AQYY01000001_gene2006	2.745e-56	203.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,264ZM@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2174)	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
GDHHQS3_k127_22989_4	871968.DESME_06805	2.4e-82	287.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,2601Y@186807|Peptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GDHHQS3_k127_22989_15	529818.AMSG_01102T0	8.409e-13	83.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota	2759|Eukaryota	V	zinc ion binding	-	GO:0000322,GO:0000323,GO:0000324,GO:0000328,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005775,GO:0005829,GO:0006914,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031974,GO:0031982,GO:0032182,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0051179,GO:0051258,GO:0051259,GO:0051641,GO:0061919,GO:0061957,GO:0065003,GO:0070013,GO:0070727,GO:0071840,GO:0072665,GO:0097708,GO:0120113	2.1.1.62	ko:K05925,ko:K17987,ko:K21997	ko04137,map04137	-	-	-	ko00000,ko00001,ko01000,ko03019,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
GDHHQS3_k127_22989_12	583355.Caka_0120	7.779e-27	129.0	COG3401@1|root,COG3401@2|Bacteria	2|Bacteria	Q	FG-GAP repeat protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_4,CBM_6,DUF5060,LRR_4,Lipase_GDSL_2,SLH,Transglut_core
GDHHQS3_k127_22989_5	926569.ANT_22190	3.576e-74	282.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_22989_11	583355.Caka_0119	2.572e-27	130.0	COG3401@1|root,COG3401@2|Bacteria	2|Bacteria	Q	FG-GAP repeat protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_4,CBM_6,DUF5060,LRR_4,Lipase_GDSL_2,SLH,Transglut_core
GDHHQS3_k127_22989_17	392499.Swit_1774	9.937e-07	62.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GDHHQS3_k127_22989_0	765420.OSCT_2276	5.899e-121	398.0	COG1092@1|root,COG1092@2|Bacteria,2G7Y9@200795|Chloroflexi,3767A@32061|Chloroflexia	32061|Chloroflexia	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_22989_9	926569.ANT_17620	1.873e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
GDHHQS3_k127_2299260_0	926569.ANT_27410	0.0	1223.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GDHHQS3_k127_2299260_11	471854.Dfer_0822	0.0009013	51.0	COG4099@1|root,COG4099@2|Bacteria,4NJFP@976|Bacteroidetes,47SYK@768503|Cytophagia	976|Bacteroidetes	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
GDHHQS3_k127_2299260_10	926569.ANT_01630	2.36e-27	119.0	2CMS6@1|root,339SN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_2299260_4	926569.ANT_02510	2.362e-75	260.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GDHHQS3_k127_2299260_8	926550.CLDAP_13470	1.016e-43	165.0	COG2087@1|root,COG2087@2|Bacteria,2G6SV@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cobalbumin biosynthesis protein	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
GDHHQS3_k127_2299260_6	926550.CLDAP_13480	2.036e-68	241.0	COG1082@1|root,COG1082@2|Bacteria,2G9PW@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GDHHQS3_k127_2299260_9	563192.HMPREF0179_00017	1.141e-43	168.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
GDHHQS3_k127_2299260_1	867845.KI911784_gene2935	8.335e-129	421.0	COG2038@1|root,COG2038@2|Bacteria,2G5R3@200795|Chloroflexi,376BT@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
GDHHQS3_k127_2299260_5	926550.CLDAP_16570	4.968e-69	238.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
GDHHQS3_k127_2299260_2	926569.ANT_02520	1.69e-115	381.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GDHHQS3_k127_2299260_3	926569.ANT_02530	4.205e-80	277.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GDHHQS3_k127_2299260_7	926569.ANT_30230	6.533e-63	221.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
GDHHQS3_k127_2315072_1	926569.ANT_30560	2.106e-146	467.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS3_k127_2315072_2	926569.ANT_30570	1.428e-133	435.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GDHHQS3_k127_2315072_0	1000565.METUNv1_04052	3.335e-148	476.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GDHHQS3_k127_2315072_4	479434.Sthe_2320	3.335e-19	97.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
GDHHQS3_k127_2315072_3	243231.GSU2308	1.25e-81	280.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
GDHHQS3_k127_2323167_1	926569.ANT_01340	1.085e-77	261.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GDHHQS3_k127_2323167_7	111780.Sta7437_3636	1.356e-09	59.0	COG1724@1|root,COG1724@2|Bacteria,1G7S1@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_2323167_5	111780.Sta7437_3635	1.124e-25	107.0	COG1598@1|root,COG1598@2|Bacteria,1GF2K@1117|Cyanobacteria,3VKUB@52604|Pleurocapsales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_2323167_4	926569.ANT_01330	1.087e-26	115.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	ycaI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS3_k127_2323167_0	926569.ANT_25030	5.146e-108	358.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GDHHQS3_k127_2323167_2	671143.DAMO_2925	2.719e-42	159.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
GDHHQS3_k127_2323167_3	671143.DAMO_2926	1.977e-38	147.0	COG0239@1|root,COG0239@2|Bacteria,2NQ56@2323|unclassified Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GDHHQS3_k127_2323167_6	316274.Haur_0149	8.694e-19	91.0	COG1051@1|root,COG1051@2|Bacteria,2G9MA@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_2323167_8	479437.Elen_1647	7.014e-07	52.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CUYQ@84998|Coriobacteriia	84998|Coriobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_2326898_10	316274.Haur_1524	3.494e-106	363.0	COG3711@1|root,COG3711@2|Bacteria	2|Bacteria	K	transcriptional antiterminator	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
GDHHQS3_k127_2326898_5	316274.Haur_1525	1.319e-153	493.0	COG2213@1|root,COG2213@2|Bacteria	2|Bacteria	G	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
GDHHQS3_k127_2326898_30	316274.Haur_1526	1.047e-31	126.0	COG2213@1|root,COG2213@2|Bacteria	2|Bacteria	G	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
GDHHQS3_k127_2326898_25	316274.Haur_1527	1.384e-42	160.0	COG4668@1|root,COG4668@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015166,GO:0015318,GO:0015575,GO:0015791,GO:0015797,GO:0015850,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090565,GO:1901618	2.7.1.197,2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02798,ko:K02799,ko:K02800,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00274	R02704,R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	iAPECO1_1312.APECO1_2858,iEC042_1314.EC042_3906,iECIAI39_1322.ECIAI39_4114,iECOK1_1307.ECOK1_4040,iECS88_1305.ECS88_4012,iECUMN_1333.ECUMN_4110,iUMN146_1321.UM146_18140,iUTI89_1310.UTI89_C4137	PTS_EIIA_2,PTS_EIIC,PTS_IIB
GDHHQS3_k127_2326898_1	316274.Haur_1528	2.996e-210	674.0	COG1080@1|root,COG1080@2|Bacteria,2G806@200795|Chloroflexi,376IB@32061|Chloroflexia	32061|Chloroflexia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
GDHHQS3_k127_2326898_0	177437.HRM2_08660	3.147e-237	746.0	COG1063@1|root,COG1063@2|Bacteria,1QA80@1224|Proteobacteria	1224|Proteobacteria	E	L-sorbose 1-phosphate reductase	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N
GDHHQS3_k127_2326898_12	177437.HRM2_08650	1.727e-97	328.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,42U95@68525|delta/epsilon subdivisions,2WQWB@28221|Deltaproteobacteria,2MNQA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS3_k127_2326898_37	671143.DAMO_0445	8.938e-09	64.0	COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria	2|Bacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GDHHQS3_k127_2326898_18	1396141.BATP01000039_gene1352	2.782e-87	293.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia,2IV5M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_2326898_38	504487.JCM19302_1747	6.803e-07	55.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2326898_36	552811.Dehly_0164	7.919e-13	71.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_2326898_39	926550.CLDAP_04930	1.117e-06	52.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2326898_16	926550.CLDAP_26530	2.698e-94	319.0	COG1609@1|root,COG1609@2|Bacteria,2G8C1@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_2326898_6	649831.L083_5589	1.673e-152	494.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4DC3J@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_2326898_9	356851.JOAN01000029_gene4939	2.315e-110	365.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4DE1N@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GDHHQS3_k127_2326898_8	1463845.JOIG01000002_gene2280	1.078e-116	384.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GDHHQS3_k127_2326898_13	1120950.KB892708_gene4260	1.9e-96	322.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4DRMF@85009|Propionibacteriales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	axe1	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
GDHHQS3_k127_2326898_28	1356854.N007_09130	4.89e-34	132.0	COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,4HDID@91061|Bacilli	91061|Bacilli	Q	acetyl esterase	cah	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
GDHHQS3_k127_2326898_2	234267.Acid_2070	8.552e-209	661.0	COG0366@1|root,COG0366@2|Bacteria,3Y6H6@57723|Acidobacteria	57723|Acidobacteria	G	Alpha amylase, catalytic domain	-	-	2.4.1.7,3.2.1.1,5.4.99.16	ko:K00690,ko:K05343	ko00500,ko01100,map00500,map01100	-	R00803,R01557,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_2326898_27	926569.ANT_26050	2.932e-37	149.0	COG5433@1|root,COG5433@2|Bacteria,2G91M@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
GDHHQS3_k127_2326898_33	926569.ANT_26040	3.525e-15	82.0	COG5433@1|root,COG5433@2|Bacteria,2G91G@200795|Chloroflexi	200795|Chloroflexi	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
GDHHQS3_k127_2326898_29	877455.Metbo_1440	1.634e-33	138.0	COG3371@1|root,arCOG02008@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_2326898_19	1449126.JQKL01000072_gene2880	3.904e-75	263.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,24DHN@186801|Clostridia,26C9Q@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2326898_34	929703.KE386491_gene2804	4.792e-14	78.0	arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes,47Q9D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2326898_24	316274.Haur_1699	6.862e-46	171.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GDHHQS3_k127_2326898_7	269797.Mbar_A0315	1.499e-120	392.0	COG0382@1|root,arCOG00476@2157|Archaea,2XWP0@28890|Euryarchaeota,2N9JB@224756|Methanomicrobia	224756|Methanomicrobia	H	UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
GDHHQS3_k127_2326898_20	684949.ATTJ01000002_gene334	1.55e-71	250.0	2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2326898_23	930171.Asphe3_21200	5.277e-48	181.0	2FGCJ@1|root,3488S@2|Bacteria,2H97A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2326898_17	439235.Dalk_4420	4.099e-91	313.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,42USJ@68525|delta/epsilon subdivisions,2WQ3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS3_k127_2326898_31	994479.GL877880_gene3858	4.004e-23	104.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DXF3@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_2326898_35	324602.Caur_3229	5.548e-13	78.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_2326898_26	765420.OSCT_1712	9.259e-40	163.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_2326898_21	1120973.AQXL01000118_gene454	7.87e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,278BX@186823|Alicyclobacillaceae	91061|Bacilli	T	helix_turn_helix, Lux Regulon	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_2326898_32	1128421.JAGA01000002_gene732	6.937e-18	85.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2326898_14	926569.ANT_04070	3.635e-95	317.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GDHHQS3_k127_2326898_3	926569.ANT_04060	7.979e-175	552.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_2326898_15	926569.ANT_04050	8.008e-95	321.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS3_k127_2326898_4	926569.ANT_04040	2.352e-174	556.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_2326898_11	926569.ANT_04030	4.482e-103	339.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_23322_4	926550.CLDAP_21020	5.121e-06	49.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_23322_3	192952.MM_1091	1.655e-39	153.0	COG0526@1|root,arCOG07612@2157|Archaea,2Y43J@28890|Euryarchaeota,2NB18@224756|Methanomicrobia	224756|Methanomicrobia	O	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
GDHHQS3_k127_23322_0	1159870.KB907784_gene2606	1.559e-237	746.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GDHHQS3_k127_23322_1	926550.CLDAP_21020	1.111e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_23322_2	926550.CLDAP_21010	4.896e-59	211.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_2341496_2	926550.CLDAP_23290	1.272e-178	575.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2341496_3	1267535.KB906767_gene4070	4.047e-74	261.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
GDHHQS3_k127_2341496_1	926569.ANT_05370	6.217e-192	608.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GDHHQS3_k127_2341496_4	926569.ANT_30550	1.404e-73	254.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS3_k127_2341496_6	161156.JQKW01000008_gene434	3.317e-26	109.0	2E46S@1|root,32Z2Q@2|Bacteria,2GIJU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2341496_0	926569.ANT_30560	7.984e-205	647.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GDHHQS3_k127_2341496_5	338963.Pcar_1481	7.738e-44	163.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42U5G@68525|delta/epsilon subdivisions,2WQ28@28221|Deltaproteobacteria,43VIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GDHHQS3_k127_2354891_3	655981.L8FQK1	2.995e-10	74.0	2C4XU@1|root,2S2WU@2759|Eukaryota,39T28@33154|Opisthokonta,3P0UQ@4751|Fungi,3QT9S@4890|Ascomycota	4751|Fungi	S	Oocyst wall protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2354891_4	1254432.SCE1572_22880	0.0001335	55.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,434N1@68525|delta/epsilon subdivisions,2WYZF@28221|Deltaproteobacteria,2Z0ZV@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS3_k127_2354891_0	112098.XP_008617902.1	1.328e-177	572.0	COG0405@1|root,KOG2410@2759|Eukaryota	2759|Eukaryota	E	glutathione hydrolase activity	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GDHHQS3_k127_2354891_2	489825.LYNGBM3L_21480	8.003e-37	142.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HGCH@1150|Oscillatoriales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_2354891_1	765420.OSCT_2101	8.296e-66	229.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_2355559_5	428126.CLOSPI_00194	2.393e-11	64.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,3VPAI@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_2355559_0	926569.ANT_28010	2.742e-216	678.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
GDHHQS3_k127_2355559_1	118166.JH976537_gene972	3.042e-134	435.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1H8R3@1150|Oscillatoriales	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2355559_3	452637.Oter_2875	1.534e-66	236.0	COG0672@1|root,COG0672@2|Bacteria,46XX5@74201|Verrucomicrobia,3K8IC@414999|Opitutae	414999|Opitutae	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
GDHHQS3_k127_2355559_2	926569.ANT_06860	2.256e-120	404.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GDHHQS3_k127_2355559_4	1382306.JNIM01000001_gene3959	2.709e-25	113.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GDHHQS3_k127_2358288_3	1151126.AQYI01000006_gene3363	9.423e-18	98.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4FKWB@85023|Microbacteriaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_2358288_2	1235457.C404_25045	2.072e-73	253.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_2358288_1	1297570.MESS4_830418	1.163e-81	290.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,43GTD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Osmosensitive K channel histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
GDHHQS3_k127_2358288_0	926569.ANT_07430	2.737e-105	349.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS3_k127_2360270_23	1123276.KB893279_gene2186	4.363e-13	73.0	2EMBT@1|root,33F0S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2360270_7	1408254.T458_09100	9.149e-100	335.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS3_k127_2360270_3	489825.LYNGBM3L_30250	1.508e-121	398.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1H9U9@1150|Oscillatoriales	1117|Cyanobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS3_k127_2360270_20	236097.ADG881_2747	1.848e-35	139.0	COG0346@1|root,COG0346@2|Bacteria,1N8P0@1224|Proteobacteria,1SGYP@1236|Gammaproteobacteria,1XPDJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_2360270_21	187303.BN69_1803	2.577e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,2UC34@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GDHHQS3_k127_2360270_15	1396418.BATQ01000076_gene706	4.495e-58	205.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_2360270_16	485913.Krac_2977	2.299e-55	200.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_2360270_12	717606.PaecuDRAFT_0852	2.084e-68	235.0	COG3832@1|root,COG3832@2|Bacteria,1U0QY@1239|Firmicutes,4IA68@91061|Bacilli,272ER@186822|Paenibacillaceae	91061|Bacilli	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2360270_24	765420.OSCT_1064	1.659e-09	64.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS3_k127_2360270_22	485913.Krac_5508	1.64e-23	107.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
GDHHQS3_k127_2360270_18	509191.AEDB02000094_gene4169	5.43e-49	177.0	COG1670@1|root,COG5646@1|root,COG1670@2|Bacteria,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,3WKGY@541000|Ruminococcaceae	186801|Clostridia	J	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
GDHHQS3_k127_2360270_25	1536773.R70331_11575	5.084e-06	54.0	COG0702@1|root,COG0702@2|Bacteria,1V6KQ@1239|Firmicutes,4HJ7A@91061|Bacilli,26SS2@186822|Paenibacillaceae	91061|Bacilli	GM	nucleoside-diphosphate sugar epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GDHHQS3_k127_2360270_2	95619.PM1_0227045	2.084e-124	415.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GDHHQS3_k127_2360270_10	485913.Krac_5625	6.582e-87	292.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GDHHQS3_k127_2360270_14	1247649.D560_0365	2.302e-62	230.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,3T6KB@506|Alcaligenaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase class IV	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GDHHQS3_k127_2360270_17	1298863.AUEP01000008_gene1241	8.656e-55	202.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
GDHHQS3_k127_2360270_9	1382306.JNIM01000001_gene1512	4.403e-87	292.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_2360270_19	1382306.JNIM01000001_gene1513	3.186e-36	146.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
GDHHQS3_k127_2360270_8	1254432.SCE1572_20265	6.553e-90	302.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_2360270_6	1254432.SCE1572_20260	4.746e-100	332.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_2360270_5	1254432.SCE1572_20255	2.876e-110	366.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,42TEH@68525|delta/epsilon subdivisions,2WPV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_2360270_4	1254432.SCE1572_20250	8.748e-116	379.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_2360270_1	1254432.SCE1572_20250	1.599e-131	434.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_2360270_11	316274.Haur_2262	4.138e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_2360270_0	316274.Haur_2261	5.44e-135	463.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,2G8T7@200795|Chloroflexi,3780G@32061|Chloroflexia	2|Bacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,dCache_1
GDHHQS3_k127_2360270_13	926569.ANT_26550	1.86e-65	232.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
GDHHQS3_k127_2360270_26	479434.Sthe_2159	8.546e-05	51.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi,27YII@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_2360485_3	926569.ANT_15680	4.896e-117	385.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi	200795|Chloroflexi	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_2360485_10	926569.ANT_14540	2.853e-35	145.0	COG0115@1|root,COG0115@2|Bacteria,2G8EE@200795|Chloroflexi	200795|Chloroflexi	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_2360485_2	1121272.KB903249_gene2216	1.881e-135	445.0	COG1653@1|root,COG1653@2|Bacteria,2IDWS@201174|Actinobacteria,4DFMA@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_2360485_6	70601.3256580	3.848e-86	297.0	COG3839@1|root,arCOG00175@2157|Archaea,2Y7MN@28890|Euryarchaeota,2431V@183968|Thermococci	183968|Thermococci	G	Function Code 14.4 Transport and Binding Proteins Carbohydrates, organic alcohols, and acids	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_2360485_5	2074.JNYD01000004_gene4950	8.027e-97	325.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4DY7F@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_2360485_4	2074.JNYD01000004_gene4951	1.649e-102	342.0	COG0395@1|root,COG0395@2|Bacteria,2IDQB@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_2360485_8	357808.RoseRS_3515	1.569e-71	249.0	COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia	32061|Chloroflexia	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_2360485_0	926569.ANT_22690	5.233e-244	767.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2360485_1	926569.ANT_22700	2.883e-236	746.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2360485_12	1463917.JODC01000007_gene7664	1.002e-09	67.0	2E9YS@1|root,3344A@2|Bacteria,2IJZ5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GDHHQS3_k127_2360485_9	246197.MXAN_4594	9.381e-62	225.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
GDHHQS3_k127_2360485_7	926560.KE387027_gene263	1.114e-81	280.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_2360485_11	391612.CY0110_11692	3.02e-18	85.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,3KG4M@43988|Cyanothece	1117|Cyanobacteria	C	Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
GDHHQS3_k127_23832_4	429009.Adeg_1147	2.402e-23	109.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,42GFG@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_23832_3	552811.Dehly_0238	1.066e-23	109.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_23832_0	926569.ANT_10810	3.773e-75	258.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GDHHQS3_k127_23832_2	926569.ANT_15850	1.403e-35	154.0	COG4745@1|root,COG4745@2|Bacteria,2G9RB@200795|Chloroflexi	200795|Chloroflexi	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_23832_1	926569.ANT_27260	2.365e-71	263.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
GDHHQS3_k127_2387344_6	1123386.AUIW01000004_gene595	2.636e-07	57.0	COG2161@1|root,COG2161@2|Bacteria,1WKH8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_2387344_1	518766.Rmar_2863	1.36e-30	125.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_2387344_3	926550.CLDAP_33390	7.561e-19	89.0	COG3039@1|root,COG3039@2|Bacteria,2G8AP@200795|Chloroflexi	200795|Chloroflexi	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
GDHHQS3_k127_2387344_2	671143.DAMO_0399	1.908e-20	94.0	COG1708@1|root,COG1708@2|Bacteria,2NS1D@2323|unclassified Bacteria	2|Bacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_2387344_4	113355.CM001775_gene2842	7.884e-12	68.0	COG1895@1|root,COG1895@2|Bacteria,1G7UH@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS3_k127_2387344_7	927677.ALVU02000001_gene4336	7.774e-05	45.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
GDHHQS3_k127_2387344_5	357808.RoseRS_2660	3.117e-10	68.0	2A53T@1|root,30TSE@2|Bacteria,2G9SA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GDHHQS3_k127_2387344_0	680198.SCAB_23781	6.82e-41	156.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_238813_14	926569.ANT_30190	2.059e-34	135.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_238813_8	926550.CLDAP_06860	1e-69	242.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GDHHQS3_k127_238813_9	926569.ANT_30170	9.37e-57	207.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
GDHHQS3_k127_238813_7	926569.ANT_30900	2.658e-122	402.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_238813_6	765420.OSCT_0206	3.771e-140	453.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,376PM@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_238813_2	765420.OSCT_0207	3.374e-215	683.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_238813_4	1042163.BRLA_c001470	2.394e-147	480.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,26QQ5@186822|Paenibacillaceae	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
GDHHQS3_k127_238813_10	926569.ANT_13170	6.822e-55	202.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_238813_11	926569.ANT_00140	3.204e-53	192.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS3_k127_238813_0	926569.ANT_31720	3.918e-300	928.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GDHHQS3_k127_238813_13	1396141.BATP01000038_gene1221	5.399e-35	147.0	COG1524@1|root,COG1524@2|Bacteria,46TNY@74201|Verrucomicrobia,2IV18@203494|Verrucomicrobiae	2|Bacteria	U	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
GDHHQS3_k127_238813_12	1396141.BATP01000038_gene1221	3.945e-48	185.0	COG1524@1|root,COG1524@2|Bacteria,46TNY@74201|Verrucomicrobia,2IV18@203494|Verrucomicrobiae	2|Bacteria	U	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
GDHHQS3_k127_238813_3	91464.S7335_3099	3.385e-166	536.0	COG0308@1|root,COG2931@1|root,COG0308@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	pepN_1	-	3.4.24.40	ko:K01269,ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
GDHHQS3_k127_238813_5	765420.OSCT_2920	9.786e-147	471.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GDHHQS3_k127_238813_15	318424.EU78_19665	3.489e-08	61.0	COG1846@1|root,COG1846@2|Bacteria,2IHTR@201174|Actinobacteria,239I0@1762|Mycobacteriaceae	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
GDHHQS3_k127_238813_1	316274.Haur_0948	9.35e-216	686.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi,376W8@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_2399645_0	404380.Gbem_2307	2.89e-134	448.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-3	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GDHHQS3_k127_2399645_2	1382306.JNIM01000001_gene2493	1.476e-05	48.0	COG1012@1|root,COG1012@2|Bacteria,2G86D@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GDHHQS3_k127_2428673_0	1283300.ATXB01000002_gene2758	0.0	1252.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria,1XFZD@135618|Methylococcales	135618|Methylococcales	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
GDHHQS3_k127_2428673_5	926569.ANT_17670	3.39e-31	125.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2428673_10	479434.Sthe_2726	6.931e-11	63.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2428673_3	765420.OSCT_2454	8.042e-98	330.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
GDHHQS3_k127_2428673_2	247490.KSU1_C0516	9.31e-106	349.0	COG1830@1|root,COG1830@2|Bacteria,2J2PV@203682|Planctomycetes	203682|Planctomycetes	G	DeoC/LacD family aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DeoC
GDHHQS3_k127_2428673_9	867903.ThesuDRAFT_00838	4.77e-20	95.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WDM8@538999|Clostridiales incertae sedis	186801|Clostridia	G	PFAM PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_2428673_4	1128421.JAGA01000003_gene3306	2.232e-48	185.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
GDHHQS3_k127_2428673_8	1408254.T458_10795	1.888e-21	97.0	COG3414@1|root,COG3414@2|Bacteria,1VHRV@1239|Firmicutes,4HXWV@91061|Bacilli	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.200	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_IIB
GDHHQS3_k127_2428673_6	888060.HMPREF9081_1330	1.641e-25	111.0	COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes	1239|Firmicutes	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.200	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_EIIA_2
GDHHQS3_k127_2428673_1	1408254.T458_10800	3.244e-156	506.0	COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HF7Z@91061|Bacilli,274V4@186822|Paenibacillaceae	91061|Bacilli	G	PTS system sugar-specific permease component	-	-	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
GDHHQS3_k127_2432257_3	1210884.HG799474_gene15133	9.325e-06	55.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
GDHHQS3_k127_2432257_2	326427.Cagg_3119	2.785e-09	61.0	2A426@1|root,30SKW@2|Bacteria,2GAFI@200795|Chloroflexi,375XZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2432257_0	926569.ANT_30000	3.139e-255	812.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
GDHHQS3_k127_2432257_1	1198452.Jab_2c34270	4.005e-37	149.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4779T@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_2440244_3	926550.CLDAP_24080	1.675e-10	69.0	COG0739@1|root,COG0739@2|Bacteria,2G8J0@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M23
GDHHQS3_k127_2440244_2	1173023.KE650771_gene4058	4.223e-27	112.0	28MFE@1|root,2ZASW@2|Bacteria,1G34V@1117|Cyanobacteria	1117|Cyanobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
GDHHQS3_k127_2440244_1	765420.OSCT_0637	7.607e-45	167.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2440244_0	485913.Krac_3951	7.245e-162	521.0	COG3666@1|root,COG3666@2|Bacteria,2G998@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
GDHHQS3_k127_2440487_2	1128421.JAGA01000002_gene1281	6.664e-85	296.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_2440487_4	316274.Haur_2801	6.473e-61	226.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_2440487_0	1499967.BAYZ01000036_gene2415	1.571e-196	624.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GDHHQS3_k127_2440487_8	317936.Nos7107_3521	2.883e-35	139.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2440487_12	215803.DB30_0629	2.278e-21	108.0	COG1020@1|root,COG1020@2|Bacteria,1NBUQ@1224|Proteobacteria,434Q7@68525|delta/epsilon subdivisions,2X8YY@28221|Deltaproteobacteria,2Z146@29|Myxococcales	28221|Deltaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
GDHHQS3_k127_2440487_9	867845.KI911784_gene3101	4.722e-27	123.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
GDHHQS3_k127_2440487_1	357808.RoseRS_3935	1.898e-115	395.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
GDHHQS3_k127_2440487_17	575609.HMPREF0629_01126	2.413e-06	56.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_2440487_3	187303.BN69_0729	1.932e-77	279.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,371I4@31993|Methylocystaceae	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding
GDHHQS3_k127_2440487_15	391625.PPSIR1_06783	5.386e-11	65.0	2DNQT@1|root,32YKZ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
GDHHQS3_k127_2440487_5	329726.AM1_3247	8.342e-53	192.0	2DNQT@1|root,32YKZ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
GDHHQS3_k127_2440487_14	926550.CLDAP_04930	3.007e-14	74.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2440487_10	765420.OSCT_0637	1.998e-23	102.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2440487_20	489825.LYNGBM3L_67340	0.000115	54.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1G5@1117|Cyanobacteria,1H794@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetratricopeptide repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_6,TPR_8
GDHHQS3_k127_2440487_19	1170562.Cal6303_0259	1.761e-05	57.0	COG1595@1|root,COG3903@1|root,COG1595@2|Bacteria,COG3903@2|Bacteria,1G5J8@1117|Cyanobacteria,1HMYS@1161|Nostocales	1117|Cyanobacteria	K	PFAM NB-ARC domain	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,NB-ARC,Sigma70_r4_2,TPR_4
GDHHQS3_k127_2440487_11	309801.trd_1552	1.171e-21	111.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_2440487_6	391625.PPSIR1_24309	9.382e-51	192.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_2440487_13	1172181.KB911701_gene973	9.091e-15	84.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_2440487_7	204669.Acid345_3825	3.975e-42	164.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS3_k127_2440487_16	66269.NL54_09380	1.509e-07	57.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria,3W2MD@53335|Pantoea	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_2440487_18	1122221.JHVI01000024_gene297	3.341e-06	55.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1WIX1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_2487173_8	926569.ANT_12920	6.847e-97	330.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
GDHHQS3_k127_2487173_10	357808.RoseRS_3344	1.016e-66	235.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GDHHQS3_k127_2487173_13	1172188.KB911822_gene707	3.573e-53	203.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_2487173_16	926569.ANT_14090	4.271e-31	129.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
GDHHQS3_k127_2487173_7	926569.ANT_14100	8.882e-98	333.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GDHHQS3_k127_2487173_20	247490.KSU1_B0699	9.423e-07	61.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
GDHHQS3_k127_2487173_18	324602.Caur_0429	4.936e-22	101.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi,375XQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
GDHHQS3_k127_2487173_12	926569.ANT_04150	7.236e-59	216.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_2487173_0	926569.ANT_04140	0.0	1298.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GDHHQS3_k127_2487173_2	926569.ANT_29200	6.971e-223	709.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GDHHQS3_k127_2487173_1	926569.ANT_29200	2.859e-232	736.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GDHHQS3_k127_2487173_15	1220534.B655_1748	9.928e-34	132.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota,23P5U@183925|Methanobacteria	183925|Methanobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_2487173_11	383372.Rcas_3135	2.434e-64	251.0	COG0642@1|root,COG1609@1|root,COG2197@1|root,COG5002@1|root,COG1609@2|Bacteria,COG2197@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2GA8I@200795|Chloroflexi,376WQ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
GDHHQS3_k127_2487173_6	926569.ANT_27790	4.85e-107	355.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_2487173_3	926550.CLDAP_35420	2.051e-175	559.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_2487173_9	926569.ANT_23140	1.295e-95	325.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_2487173_21	221109.22777914	0.0005953	46.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,23KVT@182709|Oceanobacillus	91061|Bacilli	S	YtxH-like protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS3_k127_2487173_4	192952.MM_3038	1.281e-116	388.0	COG0675@1|root,arCOG00684@2157|Archaea,2XSWB@28890|Euryarchaeota,2NAE6@224756|Methanomicrobia	224756|Methanomicrobia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GDHHQS3_k127_2487173_5	477974.Daud_0100	4.374e-109	362.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GDHHQS3_k127_2487173_14	324602.Caur_2859	8.27e-51	192.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS3_k127_2487173_19	635013.TherJR_2284	4.742e-07	60.0	2CEA6@1|root,32D7X@2|Bacteria,1V9H5@1239|Firmicutes,24KZA@186801|Clostridia,26222@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_248789_0	880073.Calab_3543	1.473e-106	364.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,2NNXM@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE5,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,MASE2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
GDHHQS3_k127_248789_1	765420.OSCT_1933	1.795e-96	329.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi,377XT@32061|Chloroflexia	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
GDHHQS3_k127_248789_4	34007.IT40_05395	1.51e-28	127.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,2PV8T@265|Paracoccus	28211|Alphaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
GDHHQS3_k127_248789_6	1226325.HMPREF1548_06244	1.836e-21	104.0	COG0596@1|root,COG0596@2|Bacteria,1UVYM@1239|Firmicutes,24HNG@186801|Clostridia	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_248789_2	1128421.JAGA01000002_gene1424	1.456e-92	314.0	COG4948@1|root,COG4948@2|Bacteria,2NP34@2323|unclassified Bacteria	2|Bacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	ycjG	GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855	4.2.1.113,5.1.1.20	ko:K02549,ko:K19802	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031,R10938	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_248789_5	1114970.PSF113_2283	6.283e-24	106.0	COG1943@1|root,COG1943@2|Bacteria,1RG4K@1224|Proteobacteria,1S8JN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_248789_8	1123508.JH636441_gene3020	8.015e-17	85.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_248789_3	1173026.Glo7428_0480	9.225e-52	193.0	COG2020@1|root,COG2020@2|Bacteria,1G57G@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
GDHHQS3_k127_248789_9	485913.Krac_1305	3.262e-16	81.0	COG1308@1|root,COG1308@2|Bacteria	2|Bacteria	K	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
GDHHQS3_k127_248789_7	926554.KI912628_gene2716	2.599e-17	83.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS3_k127_2493097_21	1303518.CCALI_02745	5.14e-49	176.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HD_5,HWE_HK,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_2493097_15	357808.RoseRS_3403	2.127e-68	240.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_2493097_20	370438.PTH_1214	9.538e-51	198.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	dltB	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
GDHHQS3_k127_2493097_33	1210884.HG799474_gene15133	1.74e-14	84.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
GDHHQS3_k127_2493097_37	765698.Mesci_5373	9.283e-06	51.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,2UUMY@28211|Alphaproteobacteria,43M2U@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GDHHQS3_k127_2493097_10	204669.Acid345_0734	1.443e-121	409.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
GDHHQS3_k127_2493097_4	326427.Cagg_3546	1.489e-162	529.0	COG0370@1|root,COG0370@2|Bacteria,2G5RW@200795|Chloroflexi,3761U@32061|Chloroflexia	32061|Chloroflexia	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
GDHHQS3_k127_2493097_18	644282.Deba_1263	2.609e-57	203.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GDHHQS3_k127_2493097_32	1232437.KL661978_gene3836	3.523e-18	87.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
GDHHQS3_k127_2493097_27	266117.Rxyl_0653	2.775e-37	149.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_2493097_23	479434.Sthe_1384	2.048e-45	173.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_2493097_8	926569.ANT_29710	8.469e-139	454.0	COG1840@1|root,COG1840@2|Bacteria,2G5QA@200795|Chloroflexi	200795|Chloroflexi	P	extracellular solute-binding protein, family 1	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
GDHHQS3_k127_2493097_0	926569.ANT_29700	4.821e-246	769.0	COG1178@1|root,COG1178@2|Bacteria,2G5Q0@200795|Chloroflexi	200795|Chloroflexi	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GDHHQS3_k127_2493097_7	926569.ANT_29690	3.449e-144	466.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_2493097_2	886293.Sinac_6978	8.131e-205	654.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_2493097_34	867903.ThesuDRAFT_02068	8.154e-13	76.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
GDHHQS3_k127_2493097_35	1313172.YM304_38650	1.576e-07	56.0	2A8HP@1|root,30XJU@2|Bacteria,2HB16@201174|Actinobacteria	201174|Actinobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GDHHQS3_k127_2493097_29	357808.RoseRS_2265	2.339e-34	139.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi,375ZR@32061|Chloroflexia	32061|Chloroflexia	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GDHHQS3_k127_2493097_38	1267535.KB906767_gene5178	0.0002677	46.0	2C2MA@1|root,2Z87X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2493097_17	1382306.JNIM01000001_gene4038	1.055e-57	211.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GDHHQS3_k127_2493097_30	318424.EU78_27805	2.088e-26	115.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,233AV@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome c oxidase, subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GDHHQS3_k127_2493097_1	383372.Rcas_3557	1.605e-229	722.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GDHHQS3_k127_2493097_13	1382306.JNIM01000001_gene4037	2.812e-76	267.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS3_k127_2493097_19	1051632.TPY_3593	4.873e-51	193.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WDBM@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_2493097_9	926550.CLDAP_35510	1.753e-136	446.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_2493097_26	926550.CLDAP_35520	9.867e-38	146.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS3_k127_2493097_14	1121468.AUBR01000025_gene2988	2.519e-74	261.0	COG3177@1|root,COG3177@2|Bacteria,1TV5J@1239|Firmicutes,24CRC@186801|Clostridia	186801|Clostridia	S	PFAM Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24,TrmB
GDHHQS3_k127_2493097_5	404589.Anae109_3304	2.172e-153	521.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42P16@68525|delta/epsilon subdivisions,2WMD4@28221|Deltaproteobacteria,2YXD8@29|Myxococcales	28221|Deltaproteobacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
GDHHQS3_k127_2493097_6	340177.Cag_0588	3.304e-152	490.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
GDHHQS3_k127_2493097_28	1121405.dsmv_2498	5.886e-36	145.0	29RCQ@1|root,30CEV@2|Bacteria,1REEK@1224|Proteobacteria,42U5Z@68525|delta/epsilon subdivisions,2WW3V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
GDHHQS3_k127_2493097_22	479434.Sthe_2091	1.033e-46	194.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
GDHHQS3_k127_2493097_12	368407.Memar_1498	4.483e-82	308.0	COG0210@1|root,arCOG00802@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K16898	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GDHHQS3_k127_2493097_16	765911.Thivi_2617	1.269e-61	217.0	COG4974@1|root,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,1S9MN@1236|Gammaproteobacteria,1X0YU@135613|Chromatiales	135613|Chromatiales	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
GDHHQS3_k127_2493097_25	485913.Krac_10713	1.4e-42	169.0	2DGVE@1|root,32U82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2493097_24	1121035.AUCH01000004_gene383	9.458e-44	171.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,2WEH2@28216|Betaproteobacteria,2KUPJ@206389|Rhodocyclales	206389|Rhodocyclales	S	BAAT Acyl-CoA thioester hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS3_k127_2493097_3	326427.Cagg_3068	1.384e-163	543.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GDHHQS3_k127_2493097_31	316274.Haur_0626	6.984e-23	106.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,377W5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GDHHQS3_k127_2493097_11	926569.ANT_19910	1.908e-92	312.0	COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi	200795|Chloroflexi	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
GDHHQS3_k127_2495218_0	1521187.JPIM01000001_gene834	1.037e-178	565.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_2495218_1	485913.Krac_4421	4.136e-51	192.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS3_k127_2495218_3	926569.ANT_24350	7.908e-13	73.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_2495218_2	1227457.C451_03814	9.155e-17	89.0	COG3385@1|root,arCOG06380@2157|Archaea	2157|Archaea	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2514298_6	926560.KE387023_gene2478	1.244e-100	332.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_2514298_4	485913.Krac_3296	9.749e-120	394.0	COG0809@1|root,COG0809@2|Bacteria,2G7UA@200795|Chloroflexi	200795|Chloroflexi	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS3_k127_2514298_16	926554.KI912673_gene2827	3.74e-06	53.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS3_k127_2514298_11	62928.azo2566	6.297e-45	180.0	COG4916@1|root,COG4916@2|Bacteria,1MXWM@1224|Proteobacteria,2WEG3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GDHHQS3_k127_2514298_1	1173028.ANKO01000130_gene1861	5.902e-156	534.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9
GDHHQS3_k127_2514298_9	290315.Clim_1144	3.779e-70	240.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
GDHHQS3_k127_2514298_10	219305.MCAG_02727	1.05e-63	231.0	COG3178@1|root,COG3178@2|Bacteria,2GNRB@201174|Actinobacteria,4DD76@85008|Micromonosporales	201174|Actinobacteria	S	'Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS3_k127_2514298_7	1306406.ASHX01000001_gene1484	1.159e-82	284.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	sseA2	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_2514298_2	357808.RoseRS_3240	2.463e-147	476.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_2514298_5	926569.ANT_03150	9.038e-115	379.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_2514298_13	696369.KI912183_gene1125	3.205e-37	148.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,261U1@186807|Peptococcaceae	186801|Clostridia	P	chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS3_k127_2514298_14	1282876.BAOK01000001_gene1190	1.91e-27	116.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,4BSK1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_2514298_3	324602.Caur_1250	1.113e-136	442.0	COG0667@1|root,COG0667@2|Bacteria,2G7Z5@200795|Chloroflexi,375GY@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_2514298_0	931276.Cspa_c04630	1.826e-232	758.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,36DGD@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS3_k127_2514298_12	926569.ANT_06060	3.275e-43	161.0	COG1970@1|root,COG1970@2|Bacteria,2G733@200795|Chloroflexi	200795|Chloroflexi	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GDHHQS3_k127_2514298_8	309801.trd_1629	1.368e-80	272.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,27XUE@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_2537630_4	1192034.CAP_8363	1.509e-12	78.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439KJ@68525|delta/epsilon subdivisions,2X4XC@28221|Deltaproteobacteria,2Z096@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_2537630_2	383372.Rcas_3166	1.485e-52	195.0	COG2086@1|root,COG2086@2|Bacteria,2G6YY@200795|Chloroflexi,374W0@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Electron transfer flavoprotein alpha beta-subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GDHHQS3_k127_2537630_1	926550.CLDAP_15410	1.644e-68	245.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GDHHQS3_k127_2537630_0	926550.CLDAP_12700	3.344e-183	591.0	COG0326@1|root,COG0326@2|Bacteria,2G60B@200795|Chloroflexi	200795|Chloroflexi	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
GDHHQS3_k127_2537630_3	478741.JAFS01000002_gene870	1.021e-45	173.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,37FUH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
GDHHQS3_k127_2538900_0	1088721.NSU_2987	0.0	1485.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2K0DW@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GDHHQS3_k127_2538900_2	626887.J057_06391	5.993e-45	175.0	COG0589@1|root,COG0589@2|Bacteria,1NAHQ@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_2538900_1	479434.Sthe_0598	1.389e-48	181.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GDHHQS3_k127_2540705_2	926569.ANT_23510	5.567e-60	225.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GDHHQS3_k127_2540705_3	1108045.GORHZ_109_00020	5.908e-43	174.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS3_k127_2540705_0	926569.ANT_00310	1.577e-79	282.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
GDHHQS3_k127_2540705_4	926569.ANT_25090	4.942e-37	150.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2559829_15	1197130.BAFM01000011_gene2051	6.612e-05	46.0	arCOG08099@1|root,arCOG08099@2157|Archaea,2XTZD@28890|Euryarchaeota,23S2K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2559829_14	235985.BBPN01000048_gene8222	3.411e-06	59.0	COG3405@1|root,COG4409@1|root,COG3405@2|Bacteria,COG4409@2|Bacteria,2ID1A@201174|Actinobacteria,2NGZY@228398|Streptacidiphilus	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2559829_2	926569.ANT_21040	7.585e-133	439.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GDHHQS3_k127_2559829_1	1128421.JAGA01000003_gene2944	3.264e-185	591.0	COG1640@1|root,COG1640@2|Bacteria,2NP2W@2323|unclassified Bacteria	2|Bacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	iJN678.malQ	Glyco_hydro_77
GDHHQS3_k127_2559829_7	1122222.AXWR01000038_gene479	2.42e-61	216.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GDHHQS3_k127_2559829_5	383372.Rcas_3054	9.414e-73	248.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GDHHQS3_k127_2559829_8	1128421.JAGA01000002_gene796	6.29e-55	197.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS3_k127_2559829_10	1123368.AUIS01000006_gene679	7.169e-43	162.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1RP41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Gluconokinase	gntK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iUTI89_1310.UTI89_C3945,iYL1228.KPN_03801	AAA_33,DctQ,SKI
GDHHQS3_k127_2559829_6	926569.ANT_21020	1.156e-69	247.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_2559829_4	1536770.R50345_02910	1.722e-88	296.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,26QNA@186822|Paenibacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GDHHQS3_k127_2559829_9	926569.ANT_21000	5.76e-53	189.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GDHHQS3_k127_2559829_0	926569.ANT_11400	1.49e-213	689.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_2559829_3	926569.ANT_11390	3.718e-118	387.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GDHHQS3_k127_2559829_12	926569.ANT_11380	2.389e-26	113.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GDHHQS3_k127_2559829_11	926569.ANT_11370	1.527e-29	128.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
GDHHQS3_k127_2559829_13	485913.Krac_0943	1.969e-07	61.0	2DRCD@1|root,33B7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_256679_8	926569.ANT_14440	5.995e-51	188.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
GDHHQS3_k127_256679_1	926569.ANT_14450	5.645e-182	573.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
GDHHQS3_k127_256679_13	1079986.JH164838_gene4310	5.764e-13	82.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ1@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_256679_10	748449.Halha_2023	1.324e-44	184.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,3WBTB@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS19835	UbiA
GDHHQS3_k127_256679_12	748727.CLJU_c40290	4.568e-32	134.0	COG1266@1|root,COG1266@2|Bacteria,1VEJJ@1239|Firmicutes,24EDW@186801|Clostridia,36GT3@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_256679_3	926569.ANT_24730	2.374e-78	267.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GDHHQS3_k127_256679_11	369723.Strop_0334	4.261e-43	173.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4DBGR@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_256679_2	118163.Ple7327_2881	1.633e-116	383.0	COG1052@1|root,COG1052@2|Bacteria,1G1BP@1117|Cyanobacteria,3VHQK@52604|Pleurocapsales	1117|Cyanobacteria	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26,1.20.1.1	ko:K00015,ko:K18916	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_256679_5	926569.ANT_25970	2.002e-62	220.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_256679_7	926569.ANT_14460	2.329e-51	191.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_256679_9	614083.AWQR01000009_gene652	4.409e-47	183.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,2VNH2@28216|Betaproteobacteria,4ACVV@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE2
GDHHQS3_k127_256679_4	926569.ANT_19600	1.215e-67	234.0	COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS3_k127_256679_6	1333998.M2A_1545	2.09e-62	221.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,4BPGB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	ccrM	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS3_k127_256679_0	1499967.BAYZ01000019_gene6268	1.062e-240	760.0	COG1026@1|root,COG1026@2|Bacteria,2NQI2@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16C associated	CP_0875	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_2574777_1	926569.ANT_22490	1.47e-65	236.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GDHHQS3_k127_2574777_3	926569.ANT_22480	6.542e-61	214.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GDHHQS3_k127_2574777_6	926569.ANT_22470	1.087e-17	85.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS3_k127_2574777_2	926569.ANT_22470	4.182e-64	222.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GDHHQS3_k127_2574777_4	926560.KE387023_gene2625	2.354e-44	168.0	COG1670@1|root,COG1670@2|Bacteria,1WMV0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_2574777_0	485916.Dtox_1182	2.571e-136	447.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_2574777_5	926569.ANT_04540	2.824e-39	149.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS3_k127_259687_13	1444309.JAQG01000082_gene3957	7.539e-10	64.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	dppA_1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_259687_10	1178825.ALIH01000002_gene1080	1.173e-37	156.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_259687_6	1238182.C882_2587	2.545e-51	194.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,2U0PD@28211|Alphaproteobacteria,2JPZE@204441|Rhodospirillales	204441|Rhodospirillales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD_5
GDHHQS3_k127_259687_5	926569.ANT_13190	4.509e-55	200.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_259687_8	572547.Amico_1311	9.762e-43	171.0	COG4927@1|root,COG4927@2|Bacteria,3TB4S@508458|Synergistetes	508458|Synergistetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
GDHHQS3_k127_259687_9	926569.ANT_13160	1.048e-38	158.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS3_k127_259687_4	926569.ANT_13140	1.855e-56	203.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_259687_2	309801.trd_0274	9.692e-72	256.0	COG5438@1|root,COG5438@2|Bacteria	2|Bacteria	S	YibE/F-like protein	yibE	-	-	-	-	-	-	-	-	-	-	-	YibE_F
GDHHQS3_k127_259687_12	1147.D082_30850	4.307e-15	77.0	2E712@1|root,331JU@2|Bacteria,1G93M@1117|Cyanobacteria,1H6V7@1142|Synechocystis	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_259687_11	211165.AJLN01000047_gene6258	3.114e-31	124.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7YD@1117|Cyanobacteria,1JIYE@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_259687_7	926569.ANT_17460	5.969e-45	181.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117,ko:K17318	ko02010,map02010	M00196,M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_259687_1	926569.ANT_27830	6.669e-114	379.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GDHHQS3_k127_259687_14	1089546.AQUI01000002_gene2798	2.914e-05	51.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mycobact_memb
GDHHQS3_k127_259687_3	926569.ANT_06830	3.807e-57	204.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GDHHQS3_k127_259687_0	926569.ANT_06840	8.759e-203	640.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GDHHQS3_k127_259687_15	1382306.JNIM01000001_gene3959	0.0003338	46.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GDHHQS3_k127_260041_6	1089553.Tph_c26220	7.684e-78	270.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia,42EUN@68295|Thermoanaerobacterales	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_17	62928.azo0356	7.023e-12	66.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2VTKI@28216|Betaproteobacteria,2KX5S@206389|Rhodocyclales	206389|Rhodocyclales	L	Very short patch repair endonuclease	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
GDHHQS3_k127_260041_14	383372.Rcas_0271	6.736e-25	106.0	2E9PK@1|root,333W0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GDHHQS3_k127_260041_13	926550.CLDAP_21940	6.495e-25	104.0	COG5428@1|root,COG5428@2|Bacteria,2G9DH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
GDHHQS3_k127_260041_19	62928.azo0356	1.551e-05	48.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2VTKI@28216|Betaproteobacteria,2KX5S@206389|Rhodocyclales	206389|Rhodocyclales	L	Very short patch repair endonuclease	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
GDHHQS3_k127_260041_10	1123288.SOV_5c01990	3.006e-34	145.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4H234@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_260041_7	637390.AFOH01000123_gene530	8.599e-66	234.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RX0F@1236|Gammaproteobacteria,2NE1A@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
GDHHQS3_k127_260041_2	1283300.ATXB01000001_gene318	3.356e-139	452.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
GDHHQS3_k127_260041_8	118166.JH976538_gene5111	1.859e-47	177.0	2AWZQ@1|root,31NXM@2|Bacteria,1G6ZZ@1117|Cyanobacteria,1HBW7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_18	324602.Caur_0711	3.712e-06	60.0	COG1807@1|root,COG1807@2|Bacteria,2GAB8@200795|Chloroflexi,374WB@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_260041_20	926550.CLDAP_25720	0.0001904	52.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GDHHQS3_k127_260041_5	1089553.Tph_c26220	3.469e-84	289.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia,42EUN@68295|Thermoanaerobacterales	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_9	1499967.BAYZ01000008_gene5408	4.496e-46	182.0	COG2931@1|root,COG2931@2|Bacteria,2NQ7A@2323|unclassified Bacteria	2|Bacteria	Q	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Calx-beta,DUF4214,DUF4347,Peptidase_C11,SLH,SWM_repeat
GDHHQS3_k127_260041_11	631454.N177_4036	8.599e-30	128.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,1JPDT@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GDHHQS3_k127_260041_12	324602.Caur_2581	2.989e-25	109.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_21	1336208.JADY01000012_gene2935	0.0003649	54.0	2DWIE@1|root,340GU@2|Bacteria,1NZ7I@1224|Proteobacteria,2USW7@28211|Alphaproteobacteria,2JXG9@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_0	1121468.AUBR01000036_gene1308	2.596e-159	528.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
GDHHQS3_k127_260041_4	311424.DhcVS_1445	4.951e-96	325.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260041_1	485913.Krac_5320	1.955e-142	456.0	COG1878@1|root,COG1878@2|Bacteria,2G8PN@200795|Chloroflexi	200795|Chloroflexi	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS3_k127_260041_15	634452.APA01_02670	1.167e-21	96.0	2DNRM@1|root,32YT2@2|Bacteria,1N8BS@1224|Proteobacteria,2UI9R@28211|Alphaproteobacteria,2JY0H@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_260041_16	1187851.A33M_0936	7.915e-18	85.0	2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,2UGJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_260041_3	926569.ANT_00880	3.098e-120	401.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_260152_14	867903.ThesuDRAFT_01803	1.421e-41	169.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
GDHHQS3_k127_260152_10	1192034.CAP_3530	1.996e-59	215.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
GDHHQS3_k127_260152_2	1303518.CCALI_01587	6.106e-143	467.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GDHHQS3_k127_260152_13	1449357.JQLK01000001_gene310	6.095e-46	176.0	COG0321@1|root,COG0321@2|Bacteria,1WIJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_260152_15	1499686.BN1079_03058	2.76e-38	156.0	COG2199@1|root,COG3706@2|Bacteria,1MZQ8@1224|Proteobacteria,1RS4B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	yneF	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,MASE1
GDHHQS3_k127_260152_1	926569.ANT_12970	5.461e-217	688.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GDHHQS3_k127_260152_12	926569.ANT_12960	1.173e-50	188.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS3_k127_260152_3	926569.ANT_12940	8e-140	457.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GDHHQS3_k127_260152_9	194439.CT0786	5.561e-64	226.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
GDHHQS3_k127_260152_7	926569.ANT_12930	1.375e-72	257.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_260152_0	926569.ANT_14570	2.807e-297	936.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
GDHHQS3_k127_260152_5	316274.Haur_4661	5.981e-130	428.0	COG0477@1|root,COG2814@2|Bacteria,2G5ZW@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_260152_16	1122915.AUGY01000001_gene7174	2.804e-37	144.0	COG4275@1|root,COG4275@2|Bacteria,1V6T7@1239|Firmicutes	1239|Firmicutes	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_260152_11	1122915.AUGY01000001_gene7175	5.296e-53	190.0	COG4275@1|root,COG4275@2|Bacteria,1VNZY@1239|Firmicutes	1239|Firmicutes	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS3_k127_260152_17	688270.Celal_0214	5.787e-24	106.0	COG0394@1|root,COG0394@2|Bacteria,4P803@976|Bacteroidetes	976|Bacteroidetes	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS3_k127_260152_4	316274.Haur_3911	1.26e-139	454.0	COG2059@1|root,COG2059@2|Bacteria,2G6NB@200795|Chloroflexi,375VI@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS3_k127_260152_6	338969.Rfer_0357	5.713e-78	265.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GDHHQS3_k127_260152_8	338969.Rfer_0358	1.83e-69	238.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_2615466_11	357808.RoseRS_3404	4.281e-69	239.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia	32061|Chloroflexia	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS3_k127_2615466_2	926569.ANT_19690	1.728e-215	676.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_2615466_14	926569.ANT_19700	4.011e-57	205.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_2615466_13	383372.Rcas_3544	3.502e-62	218.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi,377YV@32061|Chloroflexia	32061|Chloroflexia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GDHHQS3_k127_2615466_9	926569.ANT_19710	2.271e-83	282.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS3_k127_2615466_18	313603.FB2170_17341	1.045e-16	81.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia,2PHTD@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GDHHQS3_k127_2615466_8	926569.ANT_22980	6.454e-88	300.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS3_k127_2615466_4	926569.ANT_09690	3.901e-165	525.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_2615466_10	926569.ANT_09700	3.661e-83	284.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GDHHQS3_k127_2615466_1	926569.ANT_09720	6.969e-220	703.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_2615466_15	926569.ANT_09730	2.045e-55	201.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
GDHHQS3_k127_2615466_6	926569.ANT_09740	5.68e-118	385.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
GDHHQS3_k127_2615466_19	457415.HMPREF1006_00612	1.181e-16	85.0	COG0851@1|root,COG0851@2|Bacteria,3TBIQ@508458|Synergistetes	508458|Synergistetes	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
GDHHQS3_k127_2615466_5	926569.ANT_09760	7.263e-123	404.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_2615466_3	926569.ANT_09770	6.999e-204	646.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GDHHQS3_k127_2615466_12	1121015.N789_13050	2.155e-63	223.0	COG2114@1|root,COG2114@2|Bacteria,1QTA2@1224|Proteobacteria,1S8ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_2615466_0	1125863.JAFN01000001_gene1578	6.749e-245	767.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
GDHHQS3_k127_2615466_7	324602.Caur_0607	2.746e-98	344.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
GDHHQS3_k127_2615466_16	357808.RoseRS_1997	3.076e-48	181.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GDHHQS3_k127_2636404_4	883112.HMPREF9707_01146	1.33e-05	54.0	COG1388@1|root,COG1388@2|Bacteria,1UKE7@1239|Firmicutes,4ITHJ@91061|Bacilli	91061|Bacilli	M	Lysin motif	-	-	3.5.1.28	ko:K22409	-	-	-	-	ko00000,ko01000	-	CBM50	-	CHAP,LysM
GDHHQS3_k127_2636404_0	926569.ANT_08950	3.804e-129	442.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
GDHHQS3_k127_2636404_3	1173022.Cri9333_0048	1.365e-14	87.0	COG0457@1|root,COG0457@2|Bacteria,1G07G@1117|Cyanobacteria,1H8X6@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
GDHHQS3_k127_2636404_1	926569.ANT_02380	4.058e-116	380.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GDHHQS3_k127_263685_0	926569.ANT_15620	2.395e-194	620.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS3_k127_263685_4	926569.ANT_15630	2.794e-31	135.0	COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi	200795|Chloroflexi	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
GDHHQS3_k127_263685_2	926569.ANT_15640	2.165e-57	211.0	COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS3_k127_263685_3	1191523.MROS_0663	1.459e-55	205.0	COG3358@1|root,COG3358@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS3_k127_263685_1	926569.ANT_11190	8.473e-108	351.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GDHHQS3_k127_2670_2	926569.ANT_09640	1.48e-112	367.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_2670_7	1120963.KB894491_gene705	2.008e-31	143.0	COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,1RRHX@1236|Gammaproteobacteria,2Q0MD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
GDHHQS3_k127_2670_6	511051.CSE_03870	4.265e-51	192.0	COG3833@1|root,COG3833@2|Bacteria	2|Bacteria	P	maltose-transporting ATPase activity	malG	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GDHHQS3_k127_2670_4	926569.ANT_09630	3.666e-64	232.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GDHHQS3_k127_2670_5	523850.TON_1086	4.369e-52	190.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,243AA@183968|Thermococci	183968|Thermococci	J	required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GDHHQS3_k127_2670_0	926569.ANT_12010	1.685e-143	462.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GDHHQS3_k127_2670_1	926569.ANT_12000	2.231e-126	417.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_2670_3	926569.ANT_11990	4.457e-93	312.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GDHHQS3_k127_268322_9	1183438.GKIL_2981	2.036e-141	454.0	COG0001@1|root,COG0001@2|Bacteria,1G162@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_268322_16	479434.Sthe_2327	1.014e-124	417.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS3_k127_268322_22	479434.Sthe_2326	2.674e-90	307.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
GDHHQS3_k127_268322_68	649761.HMPREF0973_01922	1.59e-11	68.0	2E5N7@1|root,330D0@2|Bacteria,4NTFC@976|Bacteroidetes,2FU36@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4491
GDHHQS3_k127_268322_10	330214.NIDE1215	2.052e-140	453.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS3_k127_268322_37	661478.OP10G_0939	2.726e-57	207.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114	1.13.11.49	ko:K09162	-	-	-	-	ko00000,ko01000	-	-	-	Chlor_dismutase
GDHHQS3_k127_268322_11	710696.Intca_0489	4.803e-136	445.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
GDHHQS3_k127_268322_15	1345697.M493_03930	3.623e-125	411.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1WEVQ@129337|Geobacillus	91061|Bacilli	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS3_k127_268322_13	717605.Theco_2570	3.701e-128	418.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,26RU4@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
GDHHQS3_k127_268322_42	767817.Desgi_2074	4.663e-48	181.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,2602S@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
GDHHQS3_k127_268322_23	1408254.T458_04785	6.335e-87	296.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
GDHHQS3_k127_268322_21	644966.Tmar_1263	1.761e-90	314.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GDHHQS3_k127_268322_8	324602.Caur_0549	1.392e-143	466.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
GDHHQS3_k127_268322_12	485913.Krac_2547	1.952e-132	434.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
GDHHQS3_k127_268322_38	552811.Dehly_0391	2.367e-54	199.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.1.3.23,5.4.2.6	ko:K01838,ko:K19270	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_268322_40	443143.GM18_3902	9.144e-49	186.0	COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1QVAY@1224|Proteobacteria,42TG1@68525|delta/epsilon subdivisions,2WVCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response receiver sensor diguanylate cyclase, PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
GDHHQS3_k127_268322_24	1502770.JQMG01000001_gene1431	4.584e-85	290.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VNMF@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_268322_36	316274.Haur_1237	1.813e-57	209.0	COG0398@1|root,COG0398@2|Bacteria,2G8YU@200795|Chloroflexi,377CD@32061|Chloroflexia	32061|Chloroflexia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_268322_6	357808.RoseRS_3142	1.102e-161	521.0	COG1249@1|root,COG1249@2|Bacteria,2G5VW@200795|Chloroflexi,377BB@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_268322_5	316274.Haur_1236	7.349e-180	572.0	COG4134@1|root,COG4134@2|Bacteria	2|Bacteria	S	Bacterial extracellular solute-binding protein	ynjB	-	-	ko:K02055,ko:K05777	ko02024,map02024	M00192,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
GDHHQS3_k127_268322_29	316274.Haur_1235	1.068e-71	252.0	COG1176@1|root,COG1176@2|Bacteria	2|Bacteria	P	putrescine transport	Z012_03375	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS3_k127_268322_30	316274.Haur_1234	1.117e-71	250.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	-	-	-	ko:K02053,ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS3_k127_268322_26	316274.Haur_1233	2.518e-75	265.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_268322_3	1121396.KB893107_gene1848	3.417e-192	614.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
GDHHQS3_k127_268322_50	246197.MXAN_4966	2.304e-35	146.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
GDHHQS3_k127_268322_28	330214.NIDE2126	8.506e-72	248.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yezE	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
GDHHQS3_k127_268322_25	931627.MycrhDRAFT_3238	5.365e-79	272.0	COG1225@1|root,COG1225@2|Bacteria,2IFM1@201174|Actinobacteria,23913@1762|Mycobacteriaceae	201174|Actinobacteria	O	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
GDHHQS3_k127_268322_52	675635.Psed_1306	7.07e-32	131.0	2E8I5@1|root,332W5@2|Bacteria,2GRF8@201174|Actinobacteria,4E68Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_268322_33	861299.J421_0662	6.108e-62	215.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GDHHQS3_k127_268322_7	324602.Caur_3056	1.055e-147	481.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_268322_54	326427.Cagg_3676	4.133e-30	124.0	COG0789@1|root,COG0789@2|Bacteria,2G9AM@200795|Chloroflexi,377U8@32061|Chloroflexia	32061|Chloroflexia	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GDHHQS3_k127_268322_39	926550.CLDAP_18520	7.114e-52	188.0	COG2608@1|root,COG2608@2|Bacteria,2G911@200795|Chloroflexi	200795|Chloroflexi	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_268322_71	1128421.JAGA01000003_gene2931	6.877e-08	57.0	2DRUP@1|root,33D4Q@2|Bacteria,2NRVU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	ko:K19059	-	-	-	-	ko00000,ko02000	1.A.72.5	-	-	MerE
GDHHQS3_k127_268322_56	525904.Tter_2080	2.088e-26	115.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
GDHHQS3_k127_268322_34	1198232.CYCME_0208	1.157e-58	210.0	COG1249@1|root,COG1249@2|Bacteria,1RGSP@1224|Proteobacteria,1S5IU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB
GDHHQS3_k127_268322_48	1128421.JAGA01000003_gene2929	4.205e-43	167.0	COG0785@1|root,COG0785@2|Bacteria,2NRAI@2323|unclassified Bacteria	2|Bacteria	O	PFAM Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
GDHHQS3_k127_268322_70	1041930.Mtc_1618	1.646e-08	58.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_268322_63	472759.Nhal_1677	1.237e-18	87.0	2E3VI@1|root,32YSQ@2|Bacteria,1N7PI@1224|Proteobacteria,1SEWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane transport protein MerF	-	-	-	ko:K19058	-	-	-	-	ko00000,ko02000	1.A.72.4	-	-	Transport_MerF
GDHHQS3_k127_268322_65	572477.Alvin_1041	8.801e-16	87.0	COG0697@1|root,COG0697@2|Bacteria,1RJFE@1224|Proteobacteria,1RZF0@1236|Gammaproteobacteria,1WWYW@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_268322_4	1128421.JAGA01000003_gene2935	2.864e-182	582.0	COG1249@1|root,COG1249@2|Bacteria,2NQD5@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	HMA,Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_268322_43	580332.Slit_2799	1.04e-46	177.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_268322_62	7719.NP_001177306.1	1.162e-18	90.0	2C27E@1|root,2S2R7@2759|Eukaryota,3A0FP@33154|Opisthokonta,3BQ2T@33208|Metazoa,3D6FG@33213|Bilateria,48EFC@7711|Chordata	33208|Metazoa	S	AhpC/TSA antioxidant enzyme	sell	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
GDHHQS3_k127_268322_41	926550.CLDAP_18680	1.197e-48	182.0	COG0558@1|root,COG0558@2|Bacteria,2G8JI@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_268322_1	857087.Metme_1103	8.934e-244	764.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidoreductase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
GDHHQS3_k127_268322_32	926550.CLDAP_35990	1.477e-65	229.0	2F1C8@1|root,33UD3@2|Bacteria,2G8D9@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_268322_64	558169.AGAV01000015_gene443	3.4e-16	81.0	COG3369@1|root,COG3369@2|Bacteria,1VFK3@1239|Firmicutes,4HNHY@91061|Bacilli	91061|Bacilli	S	SMART zinc finger CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GDHHQS3_k127_268322_53	869210.Marky_0299	5.818e-31	125.0	COG3370@1|root,COG3370@2|Bacteria,1WKRN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
GDHHQS3_k127_268322_49	926569.ANT_15100	6.321e-43	159.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_268322_45	1382356.JQMP01000003_gene1897	2.909e-46	175.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS3_k127_268322_17	755178.Cyan10605_2558	1.354e-101	338.0	COG0730@1|root,COG0730@2|Bacteria,1G456@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GDHHQS3_k127_268322_20	65093.PCC7418_3088	3.516e-94	325.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_268322_27	309807.SRU_2159	2.8e-75	266.0	COG3173@1|root,COG3173@2|Bacteria,4PIG6@976|Bacteroidetes,1FJU2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GDHHQS3_k127_268322_57	907348.TresaDRAFT_2516	2.319e-25	109.0	COG0296@1|root,COG0296@2|Bacteria,2J7YS@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
GDHHQS3_k127_268322_19	926569.ANT_18490	1.126e-95	319.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS3_k127_268322_2	485913.Krac_8287	1.152e-240	761.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS3_k127_268322_58	926569.ANT_20770	4.278e-25	107.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GDHHQS3_k127_268322_0	945713.IALB_1964	3.918e-302	951.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9	ko:K00033,ko:K00616,ko:K01810,ko:K08300,ko:K13810	ko00010,ko00030,ko00480,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,map00010,map00030,map00480,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230,map03018	M00001,M00004,M00006,M00007,M00114,M00394	R01528,R01827,R02739,R02740,R03321,R10221	RC00001,RC00376,RC00439,RC00539,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS3_k127_268322_18	1254432.SCE1572_28920	3.301e-99	329.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
GDHHQS3_k127_268322_47	1121015.N789_12055	1.7e-45	172.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria	1224|Proteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
GDHHQS3_k127_268322_67	479434.Sthe_2194	6.733e-13	75.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
GDHHQS3_k127_268322_44	316274.Haur_1237	2.02e-46	176.0	COG0398@1|root,COG0398@2|Bacteria,2G8YU@200795|Chloroflexi,377CD@32061|Chloroflexia	32061|Chloroflexia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_268322_31	926550.CLDAP_03620	2.753e-66	233.0	COG0062@1|root,COG0062@2|Bacteria,2G8T6@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	-	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
GDHHQS3_k127_268322_61	595460.RRSWK_00516	9.351e-20	97.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_268322_51	595460.RRSWK_00516	1.14e-33	138.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_268322_60	66897.DJ64_23480	5.839e-22	106.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_268322_66	641526.ADIWIN_2520	2.342e-15	82.0	2E6UR@1|root,331EF@2|Bacteria,4NW12@976|Bacteroidetes,1I63K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_268322_14	1121946.AUAX01000008_gene7362	2.806e-125	412.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4D9VG@85008|Micromonosporales	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
GDHHQS3_k127_268322_69	795359.TOPB45_0125	9.948e-11	65.0	2DPS5@1|root,3335G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
GDHHQS3_k127_268322_72	392499.Swit_2410	9.448e-07	51.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,2K1TH@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GDHHQS3_k127_2723955_1	357808.RoseRS_1605	5.128e-265	837.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_2723955_4	926569.ANT_15320	4.673e-137	448.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_2723955_10	349521.HCH_01576	6.212e-84	295.0	2E47A@1|root,32Z36@2|Bacteria,1NIP8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2723955_24	926569.ANT_22500	4.442e-26	111.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GDHHQS3_k127_2723955_8	926569.ANT_22510	5.578e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_2723955_5	926569.ANT_28150	2.699e-129	429.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_2723955_14	926569.ANT_03890	6.126e-61	224.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2723955_21	926569.ANT_03880	1.074e-32	133.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GDHHQS3_k127_2723955_6	926550.CLDAP_16810	2.434e-126	418.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_2723955_17	926569.ANT_03850	3.039e-51	202.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GDHHQS3_k127_2723955_18	926569.ANT_03840	1.35e-48	181.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GDHHQS3_k127_2723955_27	926569.ANT_27460	8.865e-13	73.0	COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi	200795|Chloroflexi	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
GDHHQS3_k127_2723955_3	926550.CLDAP_31520	4.777e-155	501.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GDHHQS3_k127_2723955_20	926569.ANT_15290	2.554e-46	172.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2723955_13	926569.ANT_15280	6.676e-65	226.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GDHHQS3_k127_2723955_0	926569.ANT_15270	7.397e-276	873.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GDHHQS3_k127_2723955_19	926569.ANT_22980	9.549e-48	181.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS3_k127_2723955_23	981383.AEWH01000059_gene2244	1.574e-29	121.0	COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,4HJMF@91061|Bacilli	91061|Bacilli	K	PadR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_2723955_28	1267533.KB906734_gene3845	1.049e-08	66.0	2DMUF@1|root,32TR1@2|Bacteria,3Y98H@57723|Acidobacteria,2JMXW@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2723955_2	926569.ANT_15250	1.424e-202	648.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
GDHHQS3_k127_2723955_22	926569.ANT_15240	5.715e-31	126.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GDHHQS3_k127_2723955_26	926569.ANT_15230	1.188e-18	88.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
GDHHQS3_k127_2723955_11	926569.ANT_15220	2.263e-67	237.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_2723955_9	926569.ANT_15210	7.403e-97	328.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GDHHQS3_k127_2723955_15	1347369.CCAD010000065_gene3754	1.613e-57	211.0	COG0596@1|root,COG0596@2|Bacteria,1V0M4@1239|Firmicutes,4HPRJ@91061|Bacilli,1ZHQC@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_2723955_29	326427.Cagg_3274	0.0001416	44.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
GDHHQS3_k127_2723955_25	1379698.RBG1_1C00001G1431	1.74e-20	93.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
GDHHQS3_k127_2723955_7	1396141.BATP01000003_gene5023	4.49e-100	340.0	COG1819@1|root,COG1819@2|Bacteria,46URP@74201|Verrucomicrobia,2IVGV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
GDHHQS3_k127_2723955_16	1265313.HRUBRA_01153	1.961e-53	194.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,1S1F0@1236|Gammaproteobacteria,1J7P3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GDHHQS3_k127_2723955_12	368407.Memar_1159	1.517e-66	240.0	COG1002@1|root,arCOG02635@2157|Archaea,2Y89Z@28890|Euryarchaeota	28890|Euryarchaeota	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
GDHHQS3_k127_2753747_1	1379698.RBG1_1C00001G0051	2.4e-48	182.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
GDHHQS3_k127_2753747_3	452637.Oter_3675	1.85e-35	147.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
GDHHQS3_k127_2753747_0	1122918.KB907267_gene6	2.966e-90	311.0	COG3919@1|root,COG3919@2|Bacteria,1V3ES@1239|Firmicutes,4HG42@91061|Bacilli,27541@186822|Paenibacillaceae	91061|Bacilli	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
GDHHQS3_k127_2753747_2	316274.Haur_1591	2.053e-44	168.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_2776811_2	926550.CLDAP_41030	0.0002185	50.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1	ko:K12132,ko:K15539	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	SH3_3,SH3_4
GDHHQS3_k127_2776811_1	909663.KI867150_gene1270	3.361e-16	83.0	COG5513@1|root,COG5513@2|Bacteria,1Q83W@1224|Proteobacteria,42XPU@68525|delta/epsilon subdivisions,2WT8K@28221|Deltaproteobacteria,2MQR1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Chagasin family peptidase inhibitor I42	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Inhibitor_I42
GDHHQS3_k127_2776811_0	861299.J421_0666	9.316e-108	361.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2836017_21	926550.CLDAP_28250	1.653e-41	156.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GDHHQS3_k127_2836017_16	926569.ANT_04910	2.817e-53	191.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_2836017_29	648996.Theam_1593	2.76e-07	54.0	COG2331@1|root,COG2331@2|Bacteria,2G5GT@200783|Aquificae	200783|Aquificae	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_2836017_3	765420.OSCT_2993	3.423e-123	410.0	COG1290@1|root,COG1290@2|Bacteria,2G7XY@200795|Chloroflexi,377D3@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
GDHHQS3_k127_2836017_19	765420.OSCT_2992	3.891e-46	173.0	COG0723@1|root,COG0723@2|Bacteria,2GB28@200795|Chloroflexi,377SJ@32061|Chloroflexia	32061|Chloroflexia	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS3_k127_2836017_9	765420.OSCT_2991	4.456e-77	274.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
GDHHQS3_k127_2836017_26	1049564.TevJSym_ap00090	1.751e-17	87.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_2836017_15	797209.ZOD2009_13082	1.19e-57	216.0	arCOG10675@1|root,arCOG10675@2157|Archaea,2XUGM@28890|Euryarchaeota,23UF3@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2836017_27	237368.SCABRO_00719	1.106e-09	64.0	COG1917@1|root,COG1917@2|Bacteria,2J3N1@203682|Planctomycetes	203682|Planctomycetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_2836017_23	765420.OSCT_1613	2.041e-34	140.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_2836017_17	926569.ANT_17670	1.784e-51	188.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_2836017_20	445973.CLOBAR_01439	1.354e-45	174.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25R34@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GDHHQS3_k127_2836017_22	485918.Cpin_5671	1.616e-39	154.0	COG0269@1|root,COG0269@2|Bacteria,4NINC@976|Bacteroidetes,1IV20@117747|Sphingobacteriia	976|Bacteroidetes	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GDHHQS3_k127_2836017_6	1123511.KB905858_gene3897	1.055e-80	281.0	COG1063@1|root,COG1063@2|Bacteria,1U9ZD@1239|Firmicutes,4H2SS@909932|Negativicutes	1239|Firmicutes	E	PFAM Alcohol dehydrogenase GroES domain protein, Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_2836017_5	180332.JTGN01000019_gene1311	3.704e-81	284.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24BVD@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS3_k127_2836017_18	526218.Sterm_0035	4.042e-51	188.0	COG0235@1|root,COG0235@2|Bacteria,379M3@32066|Fusobacteria	32066|Fusobacteria	G	L-ribulose-5-phosphate 4-epimerase	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
GDHHQS3_k127_2836017_25	1033733.CAEK01000001_gene204	2.989e-21	100.0	COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,24M7N@186801|Clostridia,22HRM@1570339|Peptoniphilaceae	186801|Clostridia	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.200	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_EIIA_2
GDHHQS3_k127_2836017_28	469618.FVAG_01022	9.817e-08	57.0	COG3414@1|root,COG3414@2|Bacteria,37AKP@32066|Fusobacteria	32066|Fusobacteria	H	system, Lactose Cellobiose specific IIB subunit	-	-	2.7.1.200	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_IIB
GDHHQS3_k127_2836017_2	1123075.AUDP01000001_gene2412	1.489e-123	409.0	COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,24ADE@186801|Clostridia,3WNN2@541000|Ruminococcaceae	186801|Clostridia	G	PTS system sugar-specific permease component	-	-	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
GDHHQS3_k127_2836017_4	935845.JADQ01000061_gene45	9.083e-115	382.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,26QCA@186822|Paenibacillaceae	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GDHHQS3_k127_2836017_11	1128421.JAGA01000003_gene3306	2.105e-67	241.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
GDHHQS3_k127_2836017_7	1089552.KI911559_gene2461	1.841e-80	280.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2JPYT@204441|Rhodospirillales	204441|Rhodospirillales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GDHHQS3_k127_2836017_1	1122947.FR7_1921	2.045e-133	432.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4H3G6@909932|Negativicutes	1239|Firmicutes	C	Transketolase, pyrimidine binding domain	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS3_k127_2836017_8	1122919.KB905586_gene3795	2.435e-78	280.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,26R2C@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_2836017_24	1122217.KB899583_gene1274	7.995e-25	106.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4H5F2@909932|Negativicutes	909932|Negativicutes	G	Phosphocarrier protein hpr	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GDHHQS3_k127_2836017_0	273068.TTE2334	1.975e-153	503.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GDHHQS3_k127_2836017_14	237368.SCABRO_03970	5.349e-58	208.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023	2.2.1.2	ko:K00616,ko:K08313,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501	TAL_FSA
GDHHQS3_k127_2836017_13	697281.Mahau_1084	6.654e-65	228.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS3_k127_2836017_10	1232410.KI421424_gene1692	3.92e-68	250.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,43V05@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF-1	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GDHHQS3_k127_2836017_12	1487923.DP73_21445	6.724e-67	237.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
GDHHQS3_k127_287634_6	926569.ANT_06540	9.325e-87	297.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_287634_9	926569.ANT_06560	1.104e-66	246.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GDHHQS3_k127_287634_3	926569.ANT_06530	2.352e-99	331.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
GDHHQS3_k127_287634_2	926569.ANT_06520	4.925e-110	361.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_287634_0	926569.ANT_06500	1.959e-137	443.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_287634_10	661478.OP10G_0619	1.321e-60	228.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
GDHHQS3_k127_287634_7	926569.ANT_06490	3.713e-83	281.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,RraA-like
GDHHQS3_k127_287634_15	378806.STAUR_1465	5.443e-37	150.0	COG0454@1|root,COG0456@2|Bacteria,1R7PK@1224|Proteobacteria	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_287634_14	315750.BPUM_3683	6.516e-38	149.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,1ZFP4@1386|Bacillus	91061|Bacilli	K	Acetyltransferase	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_287634_16	68570.DC74_7296	2.863e-17	85.0	2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_287634_11	1382358.JHVN01000014_gene1589	1.619e-60	217.0	COG0330@1|root,COG0330@2|Bacteria,1TR6S@1239|Firmicutes,4HKDW@91061|Bacilli	91061|Bacilli	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_287634_1	926569.ANT_17710	7.578e-133	430.0	COG1216@1|root,COG1216@2|Bacteria,2G961@200795|Chloroflexi	200795|Chloroflexi	H	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_287634_12	608538.HTH_0014	1.984e-55	201.0	COG1451@1|root,COG1451@2|Bacteria,2G4JB@200783|Aquificae	200783|Aquificae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GDHHQS3_k127_287634_5	65393.PCC7424_0063	1.706e-87	299.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3KJY9@43988|Cyanothece	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
GDHHQS3_k127_287634_4	926569.ANT_15450	9.552e-96	323.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS3_k127_287634_8	99598.Cal7507_3979	3.791e-80	273.0	COG0500@1|root,COG2226@2|Bacteria,1GCAE@1117|Cyanobacteria,1HQK1@1161|Nostocales	1117|Cyanobacteria	H	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_2960792_15	926569.ANT_21170	3.539e-29	129.0	COG4974@1|root,COG4974@2|Bacteria,2G8U5@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
GDHHQS3_k127_2960792_17	926569.ANT_06090	7.369e-25	115.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,WXG100
GDHHQS3_k127_2960792_1	926569.ANT_06990	1.886e-196	625.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GDHHQS3_k127_2960792_2	926569.ANT_07650	2.912e-165	529.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_2960792_7	926569.ANT_07660	2.751e-98	326.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_2960792_6	926569.ANT_07670	1.105e-99	339.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_2960792_4	56780.SYN_00606	1.067e-116	392.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GDHHQS3_k127_2960792_3	926569.ANT_30540	9.369e-119	396.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2960792_8	926569.ANT_01590	9.785e-93	318.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
GDHHQS3_k127_2960792_5	926569.ANT_14770	8.408e-101	335.0	COG2519@1|root,COG2519@2|Bacteria,2G8GD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
GDHHQS3_k127_2960792_14	926569.ANT_14780	3.026e-41	162.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_2960792_12	926569.ANT_14790	2.849e-55	202.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GDHHQS3_k127_2960792_11	929556.Solca_0606	3.534e-57	205.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1IYCA@117747|Sphingobacteriia	976|Bacteroidetes	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
GDHHQS3_k127_2960792_20	870187.Thini_1566	2.794e-12	70.0	COG2886@1|root,COG2886@2|Bacteria,1NC0I@1224|Proteobacteria,1SD54@1236|Gammaproteobacteria,4634V@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GDHHQS3_k127_2960792_22	870187.Thini_3439	0.000355	46.0	COG2405@1|root,COG2405@2|Bacteria,1NBEA@1224|Proteobacteria,1TKCF@1236|Gammaproteobacteria,4633H@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GDHHQS3_k127_2960792_18	1499967.BAYZ01000041_gene2313	2.618e-20	94.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GDHHQS3_k127_2960792_21	1345023.M467_10165	6.165e-06	53.0	COG2808@1|root,COG2808@2|Bacteria,1UYCC@1239|Firmicutes,4HDSJ@91061|Bacilli	91061|Bacilli	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
GDHHQS3_k127_2960792_19	383372.Rcas_1314	5.561e-17	83.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2960792_10	383372.Rcas_1313	3.389e-62	220.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_2960792_0	1122222.AXWR01000018_gene2633	7.139e-309	967.0	COG4096@1|root,COG4096@2|Bacteria,1WN70@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Type I site-specific restriction-modification system, R (Restriction) subunit and related	-	-	-	-	-	-	-	-	-	-	-	-	EcoEI_R_C,Helicase_C,ResIII
GDHHQS3_k127_2960792_9	676032.FN3523_1189	3.366e-69	250.0	COG0732@1|root,COG0732@2|Bacteria,1Q4FB@1224|Proteobacteria,1S2MB@1236|Gammaproteobacteria,461A4@72273|Thiotrichales	72273|Thiotrichales	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
GDHHQS3_k127_2960792_13	693986.MOC_5855	4.616e-43	175.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2UGH6@28211|Alphaproteobacteria,1JRY9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GDHHQS3_k127_296488_4	290315.Clim_1053	1.977e-12	67.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
GDHHQS3_k127_296488_3	670487.Ocepr_2155	1.896e-40	153.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_296488_1	1267533.KB906735_gene4630	4.711e-144	470.0	COG0475@1|root,COG0475@2|Bacteria,3Y9G2@57723|Acidobacteria,2JNWD@204432|Acidobacteriia	204432|Acidobacteriia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GDHHQS3_k127_296488_2	324602.Caur_0597	2.324e-61	215.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS3_k127_296488_0	383372.Rcas_1569	3.674e-157	516.0	COG1404@1|root,COG1404@2|Bacteria,2G80X@200795|Chloroflexi,375FY@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GDHHQS3_k127_2968451_16	309807.SRU_2185	1.332e-19	96.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_2968451_2	926569.ANT_15110	1.639e-114	372.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_2968451_15	926569.ANT_15120	1.606e-24	104.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2968451_13	926569.ANT_15130	3.982e-43	163.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_2968451_1	926569.ANT_15140	3.881e-118	396.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
GDHHQS3_k127_2968451_6	926569.ANT_15150	6.807e-83	286.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GDHHQS3_k127_2968451_0	926569.ANT_15160	1.458e-278	868.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GDHHQS3_k127_2968451_10	326427.Cagg_0444	3.374e-52	191.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi,375QR@32061|Chloroflexia	32061|Chloroflexia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_2968451_9	316274.Haur_4010	4.512e-68	243.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
GDHHQS3_k127_2968451_12	765420.OSCT_0267	4.939e-46	179.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,375WI@32061|Chloroflexia	32061|Chloroflexia	EM	PFAM dihydrodipicolinate synthetase	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS3_k127_2968451_14	1121289.JHVL01000045_gene1131	3.724e-26	111.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,36M0F@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
GDHHQS3_k127_2968451_5	926569.ANT_10920	1.035e-85	291.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GDHHQS3_k127_2968451_4	1173026.Glo7428_2034	8.123e-95	322.0	COG3268@1|root,COG3268@2|Bacteria,1G3XG@1117|Cyanobacteria	1117|Cyanobacteria	S	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
GDHHQS3_k127_2968451_11	941449.dsx2_1999	1.415e-51	188.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RIQ@68525|delta/epsilon subdivisions,2WNC7@28221|Deltaproteobacteria,2MBBN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YbhB YbcL family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GDHHQS3_k127_2968451_7	118161.KB235922_gene1281	2.989e-76	260.0	COG2258@1|root,COG2258@2|Bacteria,1GBNP@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_2968451_8	926569.ANT_05890	2.163e-75	261.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GDHHQS3_k127_2968451_3	926569.ANT_05900	1.648e-102	337.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_3064019_6	1379270.AUXF01000002_gene1135	3.065e-07	55.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_3064019_1	926569.ANT_18930	1.058e-87	310.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
GDHHQS3_k127_3064019_5	123214.PERMA_1762	2.049e-19	92.0	COG0607@1|root,COG0607@2|Bacteria,2G4DG@200783|Aquificae	200783|Aquificae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_3064019_0	316274.Haur_1148	4.649e-240	763.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi,37562@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GDHHQS3_k127_3064019_2	525897.Dbac_1216	2.352e-75	259.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2M8X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
GDHHQS3_k127_3064019_3	926560.KE387023_gene2224	2.87e-57	207.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
GDHHQS3_k127_3064019_4	562970.Btus_2406	1.177e-52	196.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,278ZI@186823|Alicyclobacillaceae	91061|Bacilli	C	Domain of unknown function (DUF3390)	yvfW	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
GDHHQS3_k127_3074327_9	247639.MGP2080_10183	8.634e-09	58.0	COG0477@1|root,COG2814@2|Bacteria,1MW95@1224|Proteobacteria,1RZ4Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	PFAM PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
GDHHQS3_k127_3074327_1	926550.CLDAP_19150	1.312e-101	347.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS3_k127_3074327_4	765420.OSCT_1925	1.722e-30	123.0	2E5N7@1|root,330D0@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4491)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4491
GDHHQS3_k127_3074327_2	1382356.JQMP01000004_gene492	4.319e-79	277.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GDHHQS3_k127_3074327_6	595460.RRSWK_00148	4.052e-22	108.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	1.3.5.5	ko:K02293	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04786,R04787,R07510,R09652,R09653,R09654	RC01214,RC01958,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC,Amino_oxidase,NAD_binding_8
GDHHQS3_k127_3074327_7	525904.Tter_0587	1.751e-17	87.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_3074327_3	485913.Krac_10314	1.311e-53	203.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
GDHHQS3_k127_3074327_0	1265505.ATUG01000001_gene4318	1.072e-127	423.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS3_k127_3106694_3	926569.ANT_15750	2.353e-115	386.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS3_k127_3106694_6	1173024.KI912152_gene591	3.202e-08	65.0	COG0477@1|root,COG2814@2|Bacteria,1G2WB@1117|Cyanobacteria	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
GDHHQS3_k127_3106694_4	926569.ANT_12780	1.845e-50	182.0	COG1586@1|root,COG1586@2|Bacteria,2G7DW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GDHHQS3_k127_3106694_1	926569.ANT_12760	1.014e-133	432.0	COG0421@1|root,COG0421@2|Bacteria,2G7ED@200795|Chloroflexi	200795|Chloroflexi	E	Spermidine synthase tetramerisation domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
GDHHQS3_k127_3106694_2	357808.RoseRS_0010	1.012e-125	422.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_3106694_0	1283300.ATXB01000001_gene2414	5.173e-163	524.0	COG3385@1|root,COG3385@2|Bacteria,1PHKQ@1224|Proteobacteria,1SIFZ@1236|Gammaproteobacteria	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GDHHQS3_k127_31907_1	926569.ANT_13070	4.768e-59	210.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_31907_2	326427.Cagg_1682	3.705e-33	131.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
GDHHQS3_k127_31907_0	383372.Rcas_2710	1.46e-74	258.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GDHHQS3_k127_31907_3	357808.RoseRS_3212	8.624e-29	121.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GDHHQS3_k127_3231959_0	1128421.JAGA01000004_gene2674	1.9e-221	697.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_3231959_4	1382306.JNIM01000001_gene2450	1.318e-24	108.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GDHHQS3_k127_3231959_1	525904.Tter_2236	3.097e-84	290.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS3_k127_3231959_2	196490.AUEZ01000042_gene7229	1.941e-83	286.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_3231959_3	309801.trd_0578	1.799e-64	224.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_3235534_0	1128421.JAGA01000003_gene2953	1.05e-306	967.0	COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
GDHHQS3_k127_3287710_7	1123399.AQVE01000048_gene398	1.645e-32	129.0	COG4113@1|root,COG4113@2|Bacteria,1N169@1224|Proteobacteria,1SIUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3287710_14	926550.CLDAP_07640	8.799e-21	93.0	COG2161@1|root,COG2161@2|Bacteria,2G9Q0@200795|Chloroflexi	200795|Chloroflexi	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_3287710_9	221288.JH992901_gene3287	5.532e-30	120.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2442 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_3287710_15	118173.KB235914_gene1628	5.519e-20	91.0	COG4634@1|root,COG4634@2|Bacteria,1G7D7@1117|Cyanobacteria,1HD5B@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3287710_17	1173028.ANKO01000051_gene1567	6.696e-16	78.0	COG4634@1|root,COG4634@2|Bacteria,1G7D7@1117|Cyanobacteria,1HD5B@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3287710_6	443143.GM18_0245	1.99e-44	164.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
GDHHQS3_k127_3287710_11	316067.Geob_0531	1.287e-29	119.0	COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,42VWN@68525|delta/epsilon subdivisions,2WTE2@28221|Deltaproteobacteria,43VNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
GDHHQS3_k127_3287710_16	1117319.PSPO_12157	1.468e-16	83.0	COG0346@1|root,COG0346@2|Bacteria,1QGYY@1224|Proteobacteria,1TEFK@1236|Gammaproteobacteria,2Q428@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_3287710_5	526222.Desal_2703	5.849e-51	192.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42RC6@68525|delta/epsilon subdivisions,2WN72@28221|Deltaproteobacteria,2MA1Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	transcription activator, effector binding	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
GDHHQS3_k127_3287710_8	1385514.N782_11565	4.414e-32	131.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,2YAMX@289201|Pontibacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_3287710_13	485916.Dtox_3658	3.62e-25	105.0	COG1724@1|root,COG1724@2|Bacteria,1VKIY@1239|Firmicutes,24UGP@186801|Clostridia	186801|Clostridia	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_3287710_10	269797.Mbar_A2369	1.177e-29	119.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y4NR@28890|Euryarchaeota,2NB66@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_3287710_19	565033.GACE_0330	9.959e-12	67.0	arCOG09589@1|root,arCOG09589@2157|Archaea,2Y5YF@28890|Euryarchaeota,247DM@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3287710_18	665577.JH993790_gene5802	1.056e-15	89.0	2ANQ4@1|root,31DPQ@2|Bacteria,2IBAV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3287710_0	196490.AUEZ01000042_gene7227	0.0	1132.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_3287710_3	1382356.JQMP01000003_gene1475	8.054e-148	470.0	COG1878@1|root,COG1878@2|Bacteria,2GBDZ@200795|Chloroflexi,27Z1S@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GDHHQS3_k127_3287710_2	926569.ANT_05670	6.916e-182	577.0	COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
GDHHQS3_k127_3287710_1	926569.ANT_05660	1.402e-183	590.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS3_k127_3287710_4	1449126.JQKL01000004_gene620	3.167e-123	410.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS3_k127_3287710_12	196490.AUEZ01000042_gene7228	1.197e-26	109.0	COG2080@1|root,COG2080@2|Bacteria,1RJC4@1224|Proteobacteria,2VEWT@28211|Alphaproteobacteria,3JXZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GDHHQS3_k127_3373469_3	926569.ANT_06180	4.279e-23	103.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GDHHQS3_k127_3373469_2	926569.ANT_09490	1.224e-47	175.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
GDHHQS3_k127_3373469_4	926569.ANT_20810	7.872e-19	89.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
GDHHQS3_k127_3373469_1	926569.ANT_20820	1.232e-107	356.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GDHHQS3_k127_3373469_0	69042.WH5701_07161	9.154e-239	743.0	COG0376@1|root,COG0376@2|Bacteria,1G1NM@1117|Cyanobacteria,1GZK3@1129|Synechococcus	1117|Cyanobacteria	H	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
GDHHQS3_k127_3382557_16	1128421.JAGA01000003_gene3128	2.132e-08	58.0	2BBY6@1|root,325GN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3382557_5	1304874.JAFY01000002_gene479	1.929e-78	271.0	COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3382557_4	926569.ANT_19030	2.917e-88	297.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GDHHQS3_k127_3382557_13	926569.ANT_19040	1.094e-30	123.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3382557_3	926569.ANT_19050	3.09e-97	329.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GDHHQS3_k127_3382557_1	926569.ANT_19070	3.697e-220	694.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GDHHQS3_k127_3382557_10	266117.Rxyl_2946	1.029e-48	180.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GDHHQS3_k127_3382557_15	1120950.KB892774_gene1261	7.24e-23	102.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DP21@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,Trans_reg_C
GDHHQS3_k127_3382557_6	405948.SACE_4652	3.855e-67	249.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DZ55@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, LuxR family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
GDHHQS3_k127_3382557_12	296591.Bpro_3192	1.879e-37	142.0	2AGAH@1|root,316G1@2|Bacteria,1N2FZ@1224|Proteobacteria,2WDAY@28216|Betaproteobacteria,4AIKB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GDHHQS3_k127_3382557_11	479434.Sthe_2248	2.1e-38	148.0	COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia	189775|Thermomicrobia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3382557_2	1005048.CFU_3993	2.637e-154	516.0	COG0318@1|root,COG2267@1|root,COG0318@2|Bacteria,COG2267@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GDHHQS3_k127_3382557_14	926554.KI912654_gene4506	5.556e-23	109.0	COG2267@1|root,COG2267@2|Bacteria,1WN05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_3382557_9	926550.CLDAP_34110	1.734e-54	216.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GDHHQS3_k127_3382557_8	1382306.JNIM01000001_gene970	2.732e-55	210.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_3382557_7	926569.ANT_23470	1.079e-61	216.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
GDHHQS3_k127_3382557_0	926569.ANT_23480	1.182e-282	927.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GDHHQS3_k127_343820_3	926569.ANT_17090	9.458e-95	334.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
GDHHQS3_k127_343820_0	56780.SYN_01128	8.771e-155	497.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_343820_5	1379698.RBG1_1C00001G1203	8.129e-75	258.0	COG1208@1|root,COG1208@2|Bacteria,2NPHW@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	mpg2	-	2.7.7.13	ko:K00966,ko:K21210	ko00051,ko00520,ko01059,ko01100,ko01110,ko01130,map00051,map00520,map01059,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R11429	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_343820_1	56780.SYN_01130	1.487e-142	458.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,43BNE@68525|delta/epsilon subdivisions,2WKIX@28221|Deltaproteobacteria,2MS1P@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_343820_2	926569.ANT_17080	2.52e-138	457.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,LicD
GDHHQS3_k127_343820_7	330214.NIDE0884	1.248e-38	153.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rhiI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	ko:K15471	-	-	-	-	ko00000,ko01000,ko01008	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_343820_4	1211817.CCAT010000083_gene1670	1.077e-90	312.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,36F7W@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_343820_6	670292.JH26_16730	3.715e-72	260.0	COG1541@1|root,COG1541@2|Bacteria,1R7WG@1224|Proteobacteria,2U4M0@28211|Alphaproteobacteria,1JWE6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
GDHHQS3_k127_3462585_18	880073.Calab_0519	3.719e-38	157.0	COG1562@1|root,COG1562@2|Bacteria,2NQ18@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.21,2.5.1.32,2.5.1.99	ko:K00801,ko:K02291,ko:K18163	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,ko04714,map00100,map00906,map00909,map01062,map01100,map01110,map01130,map04714	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	SQS_PSY
GDHHQS3_k127_3462585_17	316067.Geob_1650	5.376e-42	159.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,43ABU@68525|delta/epsilon subdivisions,2WVAV@28221|Deltaproteobacteria,43UYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS3_k127_3462585_7	403833.Pmob_0983	7.251e-85	288.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	ytnM	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
GDHHQS3_k127_3462585_4	926569.ANT_25980	5.461e-130	428.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GDHHQS3_k127_3462585_1	926569.ANT_25960	1.904e-160	510.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS3_k127_3462585_25	349741.Amuc_0036	0.0007966	51.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
GDHHQS3_k127_3462585_24	926569.ANT_25960	5.471e-07	52.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GDHHQS3_k127_3462585_21	765420.OSCT_2115	3.319e-12	78.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3462585_0	1040986.ATYO01000002_gene3904	2.653e-181	580.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GDHHQS3_k127_3462585_20	1307761.L21SP2_1298	9.726e-33	131.0	2DSTU@1|root,33HDW@2|Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_3462585_15	1380394.JADL01000004_gene5910	3.758e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,1MZD3@1224|Proteobacteria,2UB4F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GDHHQS3_k127_3462585_10	1405.DJ92_5164	5.548e-64	223.0	COG1670@1|root,COG1670@2|Bacteria,1V5WS@1239|Firmicutes,4HH37@91061|Bacilli,1ZEZG@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_3462585_8	251221.35211202	2.369e-81	287.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
GDHHQS3_k127_3462585_5	1379698.RBG1_1C00001G1677	2.141e-126	412.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GDHHQS3_k127_3462585_22	502025.Hoch_3426	9.782e-12	77.0	COG1331@1|root,COG1331@2|Bacteria,1NF9Z@1224|Proteobacteria,43AQ1@68525|delta/epsilon subdivisions,2WXG6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3462585_14	485913.Krac_2673	7.377e-47	176.0	COG0637@1|root,COG0637@2|Bacteria,2G8S9@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_3462585_23	1242864.D187_002590	4.248e-11	67.0	2APNA@1|root,31ERS@2|Bacteria,1QA23@1224|Proteobacteria,434S9@68525|delta/epsilon subdivisions,2WZ3B@28221|Deltaproteobacteria,2Z18I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3462585_9	926569.ANT_01660	3.228e-81	275.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
GDHHQS3_k127_3462585_2	926569.ANT_01650	1.828e-150	480.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
GDHHQS3_k127_3462585_19	926569.ANT_00080	9.509e-36	141.0	COG1725@1|root,COG1725@2|Bacteria,2G7C5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GDHHQS3_k127_3462585_3	926569.ANT_00090	1.993e-134	434.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	2|Bacteria	O	PFAM band 7 protein	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3462585_13	926569.ANT_00100	3.729e-51	188.0	COG5658@1|root,COG5658@2|Bacteria,2G714@200795|Chloroflexi	200795|Chloroflexi	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
GDHHQS3_k127_3462585_6	309807.SRU_0641	1.098e-87	303.0	COG0675@1|root,COG0675@2|Bacteria,4P0KK@976|Bacteroidetes,1FJQR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
GDHHQS3_k127_3462585_11	1504823.CCMM01000010_gene1220	9.199e-62	214.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS3_k127_3463513_4	926569.ANT_21060	3.996e-94	316.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
GDHHQS3_k127_3463513_1	1379698.RBG1_1C00001G1223	8.898e-104	349.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_3463513_5	1047013.AQSP01000119_gene1311	5.124e-93	316.0	COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria	2|Bacteria	E	Ornithine cyclodeaminase/mu-crystallin family	rapL	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_3463513_6	1173021.ALWA01000037_gene3519	3.033e-43	169.0	COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
GDHHQS3_k127_3463513_3	1128421.JAGA01000002_gene1298	4.262e-96	319.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS3_k127_3463513_2	926550.CLDAP_29810	3.143e-99	331.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_3463513_0	311403.Arad_9357	2.169e-110	370.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,4B9PR@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2,DUF3382
GDHHQS3_k127_3466301_3	1278073.MYSTI_03346	6.028e-200	637.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_3466301_2	215803.DB30_3757	8.38e-224	703.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria,2YUBS@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
GDHHQS3_k127_3466301_22	926569.ANT_29450	3.905e-48	185.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
GDHHQS3_k127_3466301_6	926569.ANT_29420	4.166e-184	592.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_3466301_33	926569.ANT_29430	3.396e-18	85.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_3466301_10	926569.ANT_29430	4.542e-109	365.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_3466301_27	324602.Caur_0026	1.571e-30	123.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GDHHQS3_k127_3466301_21	867845.KI911784_gene2784	4.888e-55	200.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia	32061|Chloroflexia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
GDHHQS3_k127_3466301_32	1125863.JAFN01000001_gene2795	1.099e-19	94.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GDHHQS3_k127_3466301_16	646529.Desaci_3265	2.046e-72	259.0	COG3303@1|root,COG3303@2|Bacteria,1VTAV@1239|Firmicutes,24ZND@186801|Clostridia,264N1@186807|Peptococcaceae	186801|Clostridia	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3466301_20	234267.Acid_3505	1.982e-55	207.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
GDHHQS3_k127_3466301_13	204669.Acid345_2602	3.162e-91	314.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
GDHHQS3_k127_3466301_19	767817.Desgi_0927	9.479e-56	204.0	COG0437@1|root,COG0437@2|Bacteria,1UAZU@1239|Firmicutes,24DY6@186801|Clostridia,26083@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S binding domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
GDHHQS3_k127_3466301_1	646529.Desaci_3271	2.026e-254	804.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R10149,R11487	RC00168,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GDHHQS3_k127_3466301_34	768706.Desor_3578	4.123e-15	78.0	COG2391@1|root,COG2391@2|Bacteria,1VJEX@1239|Firmicutes,25I6C@186801|Clostridia,266AI@186807|Peptococcaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS3_k127_3466301_30	646529.Desaci_3272	3.775e-22	98.0	COG2391@1|root,COG2391@2|Bacteria,1VJEX@1239|Firmicutes,25I6C@186801|Clostridia,266AI@186807|Peptococcaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS3_k127_3466301_23	913865.DOT_4642	1.236e-38	150.0	COG2391@1|root,COG2391@2|Bacteria,1VDTV@1239|Firmicutes,24QRU@186801|Clostridia,266NH@186807|Peptococcaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GDHHQS3_k127_3466301_29	913865.DOT_4643	2.275e-22	107.0	2ENTF@1|root,33GEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3466301_28	926569.ANT_27650	4.401e-26	112.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS3_k127_3466301_17	926569.ANT_15430	4.986e-66	231.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
GDHHQS3_k127_3466301_26	926569.ANT_18000	2.585e-31	126.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GDHHQS3_k127_3466301_15	926569.ANT_17990	7.25e-76	260.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS3_k127_3466301_35	926550.CLDAP_23490	1.502e-13	85.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS3_k127_3466301_11	926550.CLDAP_19490	1.492e-106	385.0	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
GDHHQS3_k127_3466301_31	926569.ANT_03430	2.988e-20	108.0	COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GDHHQS3_k127_3466301_8	926569.ANT_17980	7.9e-137	439.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GDHHQS3_k127_3466301_0	926569.ANT_17970	4.457e-258	801.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_3466301_5	926569.ANT_17960	5.028e-188	596.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GDHHQS3_k127_3466301_4	926569.ANT_17940	2.359e-190	601.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_3466301_18	926569.ANT_17930	1.003e-57	203.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GDHHQS3_k127_3466301_24	926569.ANT_17920	3.09e-37	143.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GDHHQS3_k127_3466301_12	926569.ANT_17910	5.206e-92	306.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	yaiS	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
GDHHQS3_k127_3466301_14	926569.ANT_17900	5.141e-89	301.0	COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_3466301_7	926569.ANT_17720	9.492e-159	511.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GDHHQS3_k127_3466301_36	1183438.GKIL_2486	3.471e-07	57.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3466301_9	1170562.Cal6303_0400	2.801e-134	442.0	COG3385@1|root,COG3385@2|Bacteria,1G2T1@1117|Cyanobacteria,1HMX0@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_3484196_6	1170562.Cal6303_2423	3.238e-88	302.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
GDHHQS3_k127_3484196_9	1298858.AUEL01000004_gene897	1.956e-44	172.0	COG3570@1|root,COG3570@2|Bacteria,1MW4R@1224|Proteobacteria,2U611@28211|Alphaproteobacteria,43H49@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
GDHHQS3_k127_3484196_2	484770.UFO1_4364	2.065e-124	409.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
GDHHQS3_k127_3484196_5	387631.Asulf_00760	1.72e-91	310.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,246MG@183980|Archaeoglobi	183980|Archaeoglobi	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GDHHQS3_k127_3484196_0	926569.ANT_22990	1.124e-171	552.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like,SusD-like_2
GDHHQS3_k127_3484196_7	926569.ANT_18630	3.217e-54	198.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
GDHHQS3_k127_3484196_4	1198452.Jab_2c25790	1.341e-99	330.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,2WEJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
GDHHQS3_k127_3484196_8	1120973.AQXL01000097_gene911	2.485e-45	173.0	COG3694@1|root,COG3694@2|Bacteria,1UZ6K@1239|Firmicutes,4HCYU@91061|Bacilli,278UJ@186823|Alicyclobacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS3_k127_3484196_10	1382306.JNIM01000001_gene1764	5.938e-44	170.0	COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GDHHQS3_k127_3484196_3	1128421.JAGA01000002_gene1693	4.765e-115	379.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_3484196_12	926569.ANT_17540	1.379e-07	59.0	COG3187@1|root,COG3187@2|Bacteria,2G7J0@200795|Chloroflexi	200795|Chloroflexi	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
GDHHQS3_k127_3484196_1	1128421.JAGA01000002_gene1517	8.966e-142	462.0	COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_3484196_13	926560.KE387023_gene3228	0.0003437	49.0	COG2133@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4733@2|Bacteria,1WI48@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glucose Sorbosone dehydrogenase	-	-	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
GDHHQS3_k127_3502873_2	1304284.L21TH_2731	2.99e-55	217.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36EKZ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1,dCache_3,sCache_3_3
GDHHQS3_k127_3502873_0	419947.MRA_3417	1.698e-133	442.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
GDHHQS3_k127_3502873_5	667632.KB890187_gene2986	1.652e-06	59.0	COG3551@1|root,COG3551@2|Bacteria,1PGKZ@1224|Proteobacteria,2WBT3@28216|Betaproteobacteria,1K7DM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3502873_1	419947.MRA_3418	5.644e-69	244.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS3_k127_3502873_4	485913.Krac_7959	4.277e-17	86.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	devR	GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02479,ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_3513542_34	411465.PEPMIC_00252	2.57e-09	61.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,22HPQ@1570339|Peptoniphilaceae	186801|Clostridia	C	ATP synthase, subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
GDHHQS3_k127_3513542_31	1231241.Mc24_02988	6.226e-16	83.0	COG0636@1|root,COG0636@2|Bacteria,2GDJY@200918|Thermotogae	200918|Thermotogae	C	F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
GDHHQS3_k127_3513542_15	1499967.BAYZ01000009_gene5286	2.357e-88	317.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
GDHHQS3_k127_3513542_21	1499967.BAYZ01000009_gene5285	3.858e-42	168.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
GDHHQS3_k127_3513542_18	926569.ANT_10540	3.817e-75	259.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GDHHQS3_k127_3513542_26	926569.ANT_10530	5.474e-31	126.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GDHHQS3_k127_3513542_13	926569.ANT_10520	2.698e-94	319.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GDHHQS3_k127_3513542_7	926569.ANT_10480	1.437e-130	432.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_3513542_6	357808.RoseRS_2999	1.921e-139	460.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi,374ZX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_3513542_1	926569.ANT_10460	9.632e-224	703.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_3513542_0	926569.ANT_10450	1.222e-303	945.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_3513542_25	926550.CLDAP_08800	5.787e-34	133.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS3_k127_3513542_24	926569.ANT_10430	1.559e-39	152.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_3513542_11	926569.ANT_10420	7.738e-102	344.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_3513542_22	926569.ANT_10410	1.048e-41	156.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GDHHQS3_k127_3513542_19	266117.Rxyl_0771	6.75e-55	201.0	arCOG06048@1|root,31EJQ@2|Bacteria,2GPSC@201174|Actinobacteria,4CQDB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3513542_17	1298880.AUEV01000002_gene1744	4.902e-83	285.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria	201174|Actinobacteria	M	Choline ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
GDHHQS3_k127_3513542_20	266117.Rxyl_0773	2.286e-54	211.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_3513542_16	1382306.JNIM01000001_gene2073	3.238e-88	302.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3513542_23	1128421.JAGA01000003_gene3663	3.926e-40	158.0	arCOG06048@1|root,31EJQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3513542_2	1128421.JAGA01000003_gene3664	8.777e-219	692.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
GDHHQS3_k127_3513542_10	1128421.JAGA01000003_gene3665	2.719e-105	351.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
GDHHQS3_k127_3513542_37	182082.CpB0532	1.708e-05	52.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS3_k127_3513542_35	195250.CM001776_gene1418	1.286e-07	56.0	2E3EN@1|root,32YDN@2|Bacteria,1G85N@1117|Cyanobacteria,1H13W@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_3513542_27	102232.GLO73106DRAFT_00019230	3.833e-29	118.0	2E5P1@1|root,330DP@2|Bacteria,1G84E@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_3513542_30	43989.cce_2898	2.168e-16	81.0	COG2026@1|root,COG2026@2|Bacteria,1GKH3@1117|Cyanobacteria,3KKHM@43988|Cyanothece	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GDHHQS3_k127_3513542_36	933262.AXAM01000098_gene3466	5.043e-07	60.0	COG3613@1|root,COG3613@2|Bacteria,1RKN9@1224|Proteobacteria,42WY0@68525|delta/epsilon subdivisions,2WTEI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3513542_4	1174528.JH992892_gene6439	6.724e-199	628.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria	1117|Cyanobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
GDHHQS3_k127_3513542_12	926569.ANT_03870	4.312e-95	322.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3513542_29	926569.ANT_03870	1.469e-20	97.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_3513542_5	926569.ANT_28330	1.232e-183	600.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_3513542_9	926560.KE387025_gene4044	6.866e-110	363.0	2C1EG@1|root,2Z7MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3513542_32	215803.DB30_8639	5.182e-11	70.0	COG0727@1|root,COG0727@2|Bacteria,1NJH8@1224|Proteobacteria,432FF@68525|delta/epsilon subdivisions,2XA02@28221|Deltaproteobacteria,2YW1E@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
GDHHQS3_k127_3513542_3	234267.Acid_5088	9.456e-205	649.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_3513542_28	1394178.AWOO02000010_gene4227	1.208e-20	96.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria,4EKQS@85012|Streptosporangiales	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_3513542_38	395493.BegalDRAFT_0606	0.0008329	48.0	COG5513@1|root,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
GDHHQS3_k127_3513542_8	357808.RoseRS_4002	9.226e-129	414.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
GDHHQS3_k127_3513542_14	1231057.AMGD01000033_gene1760	1.07e-89	304.0	COG0765@1|root,COG0765@2|Bacteria,1TRX4@1239|Firmicutes,4HEAH@91061|Bacilli,26H1Y@186818|Planococcaceae	91061|Bacilli	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
GDHHQS3_k127_3529883_7	765420.OSCT_1969	4.123e-28	115.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi,376W8@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_3529883_0	926550.CLDAP_22330	3.091e-243	768.0	COG1132@1|root,COG1132@2|Bacteria,2G63W@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_3529883_6	195103.CPF_0794	9.765e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,1VBB4@1239|Firmicutes,24SIE@186801|Clostridia,36KMF@31979|Clostridiaceae	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_3529883_5	926569.ANT_19610	2.266e-63	224.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_3529883_1	926569.ANT_06880	8.156e-114	399.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
GDHHQS3_k127_3529883_2	926569.ANT_03110	8.987e-91	308.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_3529883_4	926569.ANT_03120	4.036e-85	293.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
GDHHQS3_k127_3529883_3	926569.ANT_00170	5.232e-87	294.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GDHHQS3_k127_3529883_8	926550.CLDAP_06330	2.356e-17	83.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GDHHQS3_k127_3548314_4	926569.ANT_29010	9.125e-132	426.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3548314_13	1131269.AQVV01000001_gene1451	2.712e-06	57.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GDHHQS3_k127_3548314_3	1305836.AXVE01000006_gene508	1.364e-133	439.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,26DAP@186818|Planococcaceae	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GDHHQS3_k127_3548314_0	926569.ANT_02400	9.345e-155	496.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS3_k127_3548314_10	926569.ANT_12820	2.214e-38	156.0	COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi	200795|Chloroflexi	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3548314_11	926569.ANT_09420	2.845e-31	132.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.16.1.3,1.5.1.41	ko:K02823,ko:K05368	ko00240,ko00740,ko00860,ko01100,map00240,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GDHHQS3_k127_3548314_5	926569.ANT_18920	1.772e-103	347.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_3548314_2	926569.ANT_09430	2.759e-136	440.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GDHHQS3_k127_3548314_1	1173026.Glo7428_1980	8.796e-143	465.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GDHHQS3_k127_3548314_12	1123248.KB893337_gene2566	3.988e-30	121.0	COG5470@1|root,COG5470@2|Bacteria,4NUEC@976|Bacteroidetes,1IZ1F@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
GDHHQS3_k127_3548314_7	926569.ANT_17240	5.605e-91	312.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
GDHHQS3_k127_3548314_9	1307761.L21SP2_2777	2.181e-39	160.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.99.1.3	ko:K02470,ko:K03833	-	-	-	-	ko00000,ko01000,ko03012,ko03032,ko03400	-	-	-	HATPase_c,HTH_20
GDHHQS3_k127_3548314_8	1041930.Mtc_1942	3.885e-46	182.0	COG0477@1|root,arCOG00132@2157|Archaea,2XW9U@28890|Euryarchaeota	28890|Euryarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GDHHQS3_k127_3548314_6	1210884.HG799462_gene7988	5.293e-92	308.0	COG0500@1|root,COG0500@2|Bacteria,2IZ18@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_3574762_1	926569.ANT_12920	1.86e-65	232.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
GDHHQS3_k127_3574762_2	1267534.KB906757_gene965	3.09e-40	151.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_3574762_0	926569.ANT_30670	4.336e-295	916.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_3574762_3	926569.ANT_23190	5.203e-29	122.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GDHHQS3_k127_3583708_4	926569.ANT_01210	9.287e-140	450.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_3583708_17	871963.Desdi_0741	1.405e-06	54.0	COG0823@1|root,COG0823@2|Bacteria,1VECP@1239|Firmicutes,24NKX@186801|Clostridia,262IG@186807|Peptococcaceae	186801|Clostridia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3583708_15	1230343.CANP01000041_gene3069	3.922e-13	76.0	COG0645@1|root,COG0645@2|Bacteria,1RHF4@1224|Proteobacteria,1S3QW@1236|Gammaproteobacteria,1JEIM@118969|Legionellales	118969|Legionellales	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GDHHQS3_k127_3583708_0	926569.ANT_01220	1.059e-245	771.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
GDHHQS3_k127_3583708_6	926569.ANT_01230	1.185e-73	254.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GDHHQS3_k127_3583708_1	926569.ANT_01240	2.667e-171	546.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_3583708_5	196162.Noca_1631	5.618e-139	447.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_3583708_7	292459.STH1632	1.016e-43	165.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,1VGJ7@1239|Firmicutes,24SQU@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_3583708_2	926569.ANT_01250	1.023e-161	515.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_3583708_3	926569.ANT_01260	3.718e-149	478.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_3583708_10	485913.Krac_2105	3.507e-33	132.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_3583708_14	1068978.AMETH_6790	1.849e-14	77.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4DZTQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_3583708_16	1123236.KB899379_gene1470	1.535e-10	72.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
GDHHQS3_k127_3583708_8	1121374.KB891587_gene3066	1.175e-38	158.0	COG5653@1|root,COG5653@2|Bacteria,1QUMR@1224|Proteobacteria,1RN5W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Seryl_tRNA_N
GDHHQS3_k127_3583708_13	349124.Hhal_1516	5.59e-15	86.0	COG3146@1|root,COG3146@2|Bacteria,1QYWX@1224|Proteobacteria,1T420@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GDHHQS3_k127_3583708_11	1198452.Jab_1c03170	3.917e-29	125.0	COG4123@1|root,COG4123@2|Bacteria,1NCED@1224|Proteobacteria	1224|Proteobacteria	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_3583708_12	1499967.BAYZ01000090_gene4950	1.965e-25	118.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_3604199_11	926569.ANT_26820	9.444e-20	90.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
GDHHQS3_k127_3604199_10	926550.CLDAP_18620	1.289e-23	105.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GDHHQS3_k127_3604199_7	357808.RoseRS_2229	1.067e-63	228.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_3604199_2	525897.Dbac_0080	3.854e-104	346.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
GDHHQS3_k127_3604199_0	204669.Acid345_1623	1.656e-200	630.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_3604199_1	926569.ANT_03090	4.106e-110	365.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_3604199_3	383372.Rcas_4449	1.074e-100	343.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi,3771I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_3604199_5	1120960.ATXG01000017_gene1388	3.207e-75	262.0	COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria,4FM9R@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
GDHHQS3_k127_3604199_6	926569.ANT_03090	7.617e-65	235.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_3604199_12	700598.Niako_2464	4.568e-09	64.0	COG1917@1|root,COG1917@2|Bacteria,4NUTA@976|Bacteroidetes,1IZA5@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_3604199_13	356851.JOAN01000001_gene3569	1.112e-06	57.0	COG3832@1|root,COG3832@2|Bacteria,2I61C@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_3604199_8	1196323.ALKF01000187_gene5786	1.437e-48	183.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,26TVZ@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Ubie_methyltran
GDHHQS3_k127_3604199_4	926569.ANT_03090	5.417e-80	280.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_3604199_9	926569.ANT_03100	4.517e-39	153.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_361775_5	316274.Haur_1681	6.155e-31	123.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi,3759N@32061|Chloroflexia	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GDHHQS3_k127_361775_8	472759.Nhal_2030	2.16e-17	94.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,1SFYU@1236|Gammaproteobacteria,1X0NT@135613|Chromatiales	135613|Chromatiales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,PKD
GDHHQS3_k127_361775_9	1068978.AMETH_5360	6.176e-12	77.0	COG1396@1|root,COG1396@2|Bacteria,2I4D2@201174|Actinobacteria	201174|Actinobacteria	K	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,N_BRCA1_IG
GDHHQS3_k127_361775_0	926569.ANT_25740	1.008e-142	479.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
GDHHQS3_k127_361775_1	926569.ANT_27990	1.118e-102	349.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926569.ANT_27990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_361775_2	926569.ANT_28000	3.151e-100	344.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
GDHHQS3_k127_361775_6	1121920.AUAU01000013_gene1720	3.526e-26	113.0	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
GDHHQS3_k127_361775_3	926569.ANT_06230	1.2e-70	246.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_361775_7	1123277.KB893172_gene671	6.76e-20	93.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
GDHHQS3_k127_361775_4	926569.ANT_06220	3.349e-53	192.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GDHHQS3_k127_361775_10	926550.CLDAP_19570	2.911e-07	56.0	2EV6B@1|root,33NM4@2|Bacteria,2G7I5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3670750_1	649638.Trad_2353	1.309e-180	604.0	COG0587@1|root,COG1372@1|root,COG0587@2|Bacteria,COG1372@2|Bacteria,1WIA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
GDHHQS3_k127_3670750_9	649747.HMPREF0083_02901	2.039e-35	139.0	COG0454@1|root,COG0456@2|Bacteria,1V3W3@1239|Firmicutes,4HHYX@91061|Bacilli,26Y5A@186822|Paenibacillaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3670750_12	1121472.AQWN01000008_gene1980	9.597e-26	111.0	COG1848@1|root,COG1848@2|Bacteria,1V9QN@1239|Firmicutes,24K4N@186801|Clostridia,262KD@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3670750_13	671143.DAMO_2522	1.202e-10	65.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_3670750_3	483219.LILAB_04255	4.715e-99	334.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,43BHV@68525|delta/epsilon subdivisions,2X6WB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS3_k127_3670750_6	1370120.AUWR01000006_gene2602	2.274e-73	255.0	COG0300@1|root,COG2267@1|root,COG0300@2|Bacteria,COG2267@2|Bacteria,2I9IM@201174|Actinobacteria,23F9W@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,adh_short
GDHHQS3_k127_3670750_8	439235.Dalk_1417	1.889e-39	149.0	COG1586@1|root,COG1586@2|Bacteria,1REQP@1224|Proteobacteria,42RVE@68525|delta/epsilon subdivisions,2WNJ5@28221|Deltaproteobacteria,2MJVH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	S-adenosylmethionine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	AdoMet_dc
GDHHQS3_k127_3670750_5	926569.ANT_29760	1.501e-79	273.0	COG2746@1|root,COG2746@2|Bacteria	2|Bacteria	V	aminoglycoside 3-N-acetyltransferase activity	yokD	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
GDHHQS3_k127_3670750_4	926550.CLDAP_07100	1.458e-91	309.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GDHHQS3_k127_3670750_15	1122223.KB890702_gene1372	7.375e-10	65.0	29AZZ@1|root,3196E@2|Bacteria,1WK0T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3670750_11	864051.BurJ1DRAFT_5009	5.823e-29	118.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GDHHQS3_k127_3670750_16	1246995.AFR_15325	3.055e-05	53.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria,4DG2C@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GDHHQS3_k127_3670750_14	1347392.CCEZ01000019_gene1069	5.223e-10	67.0	COG3945@1|root,COG3945@2|Bacteria,1V3TS@1239|Firmicutes,24HUR@186801|Clostridia,36J27@31979|Clostridiaceae	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS3_k127_3670750_10	228410.NE0622	1.714e-32	130.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_3670750_7	690850.Desaf_0951	2.029e-57	208.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,42TJI@68525|delta/epsilon subdivisions,2WQM5@28221|Deltaproteobacteria,2MAMM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS3_k127_3670750_0	1123073.KB899241_gene2287	1.626e-203	638.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
GDHHQS3_k127_3670750_2	1123073.KB899241_gene2286	4.168e-106	347.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,1X5MS@135614|Xanthomonadales	135614|Xanthomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_3696487_13	1519464.HY22_00675	2.459e-25	112.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.29,6.3.2.30	ko:K03802,ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
GDHHQS3_k127_3696487_12	926569.ANT_22780	2.553e-47	176.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GDHHQS3_k127_3696487_11	998674.ATTE01000001_gene3785	2.335e-50	186.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_3696487_17	1499967.BAYZ01000078_gene980	4.866e-14	77.0	2DFUU@1|root,2ZT8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3696487_4	926569.ANT_13200	2.308e-172	550.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
GDHHQS3_k127_3696487_7	930169.B5T_00908	2.615e-83	280.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,1S427@1236|Gammaproteobacteria,1XK8X@135619|Oceanospirillales	135619|Oceanospirillales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_3696487_1	926569.ANT_13210	1.215e-230	719.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3696487_16	1051501.AYTL01000027_gene884	5.356e-15	87.0	COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,1ZCTN@1386|Bacillus	91061|Bacilli	E	Amidinotransferase	ykgA	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
GDHHQS3_k127_3696487_5	926569.ANT_13220	2.177e-163	533.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi	200795|Chloroflexi	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GDHHQS3_k127_3696487_14	926569.ANT_13230	1.827e-23	104.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GDHHQS3_k127_3696487_10	926569.ANT_23090	5.595e-51	190.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	Gmad2,LysM
GDHHQS3_k127_3696487_0	926569.ANT_23100	0.0	1463.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GDHHQS3_k127_3696487_9	926569.ANT_20740	1.771e-70	243.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_3696487_8	926569.ANT_20750	5.478e-80	275.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS3_k127_3696487_2	926550.CLDAP_15280	1.101e-210	681.0	COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi	200795|Chloroflexi	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
GDHHQS3_k127_3696487_6	926569.ANT_13130	4.467e-96	322.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_3696487_3	926569.ANT_13370	4.016e-204	642.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS3_k127_372967_4	383372.Rcas_1231	2.145e-142	457.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi,376UE@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
GDHHQS3_k127_372967_3	926569.ANT_28810	8.918e-173	549.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
GDHHQS3_k127_372967_14	762966.HMPREF9439_02711	0.000299	52.0	2ARK2@1|root,31GWK@2|Bacteria,1P9S9@1224|Proteobacteria	1224|Proteobacteria	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GDHHQS3_k127_372967_6	489825.LYNGBM3L_13780	1.793e-36	140.0	292PR@1|root,2ZQ7J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_372967_11	113355.CM001775_gene1335	4.1e-16	83.0	2C5EY@1|root,32YQJ@2|Bacteria,1G8TB@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_372967_13	33178.CADATEAP00004055	1.21e-10	64.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi,3R1JE@4890|Ascomycota,20P6X@147545|Eurotiomycetes	4751|Fungi	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
GDHHQS3_k127_372967_12	1313172.YM304_04440	5.562e-14	78.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
GDHHQS3_k127_372967_10	521674.Plim_1218	1.488e-16	87.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_372967_1	926569.ANT_28820	2.41e-175	559.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
GDHHQS3_k127_372967_2	926569.ANT_24720	2.208e-174	563.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GDHHQS3_k127_372967_0	926569.ANT_19080	2.274e-181	579.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GDHHQS3_k127_372967_5	316274.Haur_1216	2.771e-80	276.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_372967_7	316274.Haur_1215	8.379e-36	141.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
GDHHQS3_k127_372967_8	357808.RoseRS_0173	1.441e-28	117.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS3_k127_372967_9	357808.RoseRS_0172	5.188e-21	94.0	2ED4G@1|root,33718@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
GDHHQS3_k127_373049_2	1521187.JPIM01000010_gene2149	5.851e-95	321.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GDHHQS3_k127_373049_0	926569.ANT_16770	4.686e-115	378.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GDHHQS3_k127_373049_1	525904.Tter_0079	1.146e-105	359.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	GshA,SecD_SecF,Sec_GG
GDHHQS3_k127_373049_5	555088.DealDRAFT_1395	2.763e-21	97.0	COG0125@1|root,COG0125@2|Bacteria,1VAQ9@1239|Firmicutes,24SXH@186801|Clostridia	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_373049_3	926569.ANT_16740	1.458e-90	310.0	COG1226@1|root,COG1226@2|Bacteria,2G7EI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_373049_4	926569.ANT_16730	2.543e-86	293.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GDHHQS3_k127_3743078_1	926569.ANT_07470	3.383e-84	285.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GDHHQS3_k127_3743078_0	926569.ANT_07480	6.072e-115	380.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GDHHQS3_k127_3743078_2	926569.ANT_07490	2.861e-75	268.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GDHHQS3_k127_3743078_3	1907.SGLAU_01635	1.306e-41	157.0	2AQME@1|root,31FUG@2|Bacteria,2GJ2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3745292_4	926569.ANT_06410	3.248e-28	117.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
GDHHQS3_k127_3745292_2	518766.Rmar_2863	3.856e-31	127.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_3745292_8	262724.TT_C1805	0.0001407	48.0	COG2161@1|root,COG2161@2|Bacteria,1WKH8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_3745292_1	99598.Cal7507_1941	1.909e-31	124.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria,1HPP8@1161|Nostocales	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
GDHHQS3_k127_3745292_5	113355.CM001775_gene2842	1.14e-19	93.0	COG1895@1|root,COG1895@2|Bacteria,1G7UH@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS3_k127_3745292_6	46234.ANA_C11113	1.901e-19	91.0	COG1708@1|root,COG1708@2|Bacteria,1G9J2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS3_k127_3745292_3	13035.Dacsa_2902	1.894e-28	115.0	COG1724@1|root,COG1724@2|Bacteria,1G9SX@1117|Cyanobacteria	1117|Cyanobacteria	N	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_3745292_7	32057.KB217478_gene6503	5.068e-17	83.0	COG1598@1|root,COG1598@2|Bacteria,1G9I1@1117|Cyanobacteria,1HPTW@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3745292_0	680198.SCAB_23781	1.007e-38	150.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_3745598_21	324925.Ppha_1935	1.704e-25	106.0	2DNRM@1|root,32YT2@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_3745598_29	1120948.KB903219_gene731	1.129e-05	53.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4E0YC@85010|Pseudonocardiales	201174|Actinobacteria	E	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_3745598_9	189425.PGRAT_10740	1.121e-70	248.0	COG4886@1|root,COG4886@2|Bacteria,1UD7W@1239|Firmicutes,4HEKM@91061|Bacilli,2749P@186822|Paenibacillaceae	91061|Bacilli	S	Leucine-rich repeats, typical (most populated) subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,LRR_8,MucBP
GDHHQS3_k127_3745598_12	1122915.AUGY01000109_gene1398	4.025e-61	217.0	COG3485@1|root,COG3485@2|Bacteria,1UY2U@1239|Firmicutes,4HDAN@91061|Bacilli	91061|Bacilli	Q	Catechol dioxygenase N terminus	clcA	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
GDHHQS3_k127_3745598_5	646529.Desaci_2502	7.796e-96	320.0	COG0412@1|root,COG0412@2|Bacteria,1UZRU@1239|Firmicutes	1239|Firmicutes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_3745598_22	58344.JOEL01000003_gene1433	4.229e-24	103.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3745598_8	521045.Kole_0611	3.339e-82	279.0	COG1272@1|root,COG1272@2|Bacteria,2GCUZ@200918|Thermotogae	200918|Thermotogae	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
GDHHQS3_k127_3745598_13	448385.sce8469	3.51e-54	200.0	COG0639@1|root,COG0639@2|Bacteria,1QQKD@1224|Proteobacteria,43EN6@68525|delta/epsilon subdivisions,2X9QX@28221|Deltaproteobacteria,2YYXC@29|Myxococcales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS3_k127_3745598_18	926550.CLDAP_33720	1.153e-35	143.0	COG1428@1|root,COG1428@2|Bacteria,2G8Z7@200795|Chloroflexi	200795|Chloroflexi	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS3_k127_3745598_6	868131.MSWAN_0806	2.064e-94	317.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GDHHQS3_k127_3745598_25	324602.Caur_1173	6.617e-18	93.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS3_k127_3745598_15	485913.Krac_7756	1.226e-49	181.0	COG1051@1|root,COG1051@2|Bacteria,2G7EC@200795|Chloroflexi	2|Bacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GDHHQS3_k127_3745598_26	316274.Haur_1757	1.251e-17	93.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,375KA@32061|Chloroflexia	32061|Chloroflexia	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS3_k127_3745598_27	1332071.L581_4374	2.093e-17	90.0	COG1183@1|root,COG1183@2|Bacteria	2|Bacteria	I	phosphatidylcholine synthase activity	pcs	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24,2.7.8.8	ko:K01004,ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800,R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_3745598_23	861299.J421_1813	4.294e-24	114.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6,Acetyltransf_9
GDHHQS3_k127_3745598_7	862908.BMS_0542	1.193e-83	297.0	COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,42MKC@68525|delta/epsilon subdivisions,2MTGC@213481|Bdellovibrionales,2WK3U@28221|Deltaproteobacteria	213481|Bdellovibrionales	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Hydrolase_4
GDHHQS3_k127_3745598_20	1332071.L581_4379	1.125e-26	121.0	COG0382@1|root,COG0382@2|Bacteria,1MYNT@1224|Proteobacteria,1SKGE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GDHHQS3_k127_3745598_3	862908.BMS_0544	3.916e-162	539.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2MTQT@213481|Bdellovibrionales,2WKYM@28221|Deltaproteobacteria	213481|Bdellovibrionales	GT	Phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GDHHQS3_k127_3745598_24	1278971.AOGF01000005_gene1525	1.809e-23	111.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,1RRAG@1236|Gammaproteobacteria,1Y81A@135625|Pasteurellales	135625|Pasteurellales	S	Cytidylyltransferase family	Z012_02625	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GDHHQS3_k127_3745598_10	1200792.AKYF01000012_gene1279	2.729e-63	224.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_3745598_14	1382306.JNIM01000001_gene1923	5.293e-53	190.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GDHHQS3_k127_3745598_19	56107.Cylst_1497	9.571e-32	129.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HP49@1161|Nostocales	1117|Cyanobacteria	S	phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
GDHHQS3_k127_3745598_2	1121382.JQKG01000026_gene2918	8.945e-188	593.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
GDHHQS3_k127_3745598_17	317619.ANKN01000158_gene1786	2.192e-41	157.0	COG4101@1|root,COG4101@2|Bacteria,1G64Q@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_3745598_28	1479237.JMLY01000001_gene2974	2.591e-06	56.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,4646A@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	adrA	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
GDHHQS3_k127_3745598_30	1219072.VHA01S_014_00990	3.948e-05	52.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1XVI8@135623|Vibrionales	135623|Vibrionales	T	Membrane associated GGDEF protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_3745598_1	324602.Caur_2513	3.13e-201	631.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GDHHQS3_k127_3745598_4	926560.KE387027_gene366	1.673e-99	340.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GDHHQS3_k127_3745598_31	1237149.C900_00684	0.0001986	52.0	COG3209@1|root,COG4733@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Big_2,DUF4988,He_PIG
GDHHQS3_k127_3745598_0	926569.ANT_15490	2.034e-283	882.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_3745598_16	159450.NH14_08630	1.12e-43	168.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2VPCI@28216|Betaproteobacteria,1K11U@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_29,rve
GDHHQS3_k127_3745598_11	395492.Rleg2_1789	1.417e-62	224.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,4B700@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
GDHHQS3_k127_3765668_6	1173024.KI912151_gene1945	4.603e-33	132.0	COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria	1117|Cyanobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GDHHQS3_k127_3765668_0	1173026.Glo7428_0555	2.234e-161	541.0	COG2203@1|root,COG3322@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3322@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_4
GDHHQS3_k127_3765668_5	1128421.JAGA01000002_gene1170	1.816e-33	146.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	asgD	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_3765668_2	383372.Rcas_2795	4.426e-49	186.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_3765668_4	1297742.A176_00861	3.779e-40	172.0	COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43BZK@68525|delta/epsilon subdivisions,2X7AC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
GDHHQS3_k127_3765668_7	1382230.ASAP_1875	7.68e-06	53.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2JQBZ@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482,ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_3765668_1	1173026.Glo7428_1118	1.613e-53	204.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G0GI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
GDHHQS3_k127_3765668_3	316274.Haur_0067	2.173e-44	171.0	COG3315@1|root,COG3315@2|Bacteria,2GAE5@200795|Chloroflexi,375R6@32061|Chloroflexia	32061|Chloroflexia	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
GDHHQS3_k127_3772454_0	926550.CLDAP_11260	1.854e-204	647.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_3772454_1	671143.DAMO_1521	1.424e-78	269.0	COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria	2|Bacteria	P	TrkA-C domain	trkA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_3772454_2	671143.DAMO_1520	4.062e-59	210.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_3782596_7	357808.RoseRS_4003	1.153e-32	131.0	COG0765@1|root,COG0765@2|Bacteria,2G845@200795|Chloroflexi,376Y4@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
GDHHQS3_k127_3782596_2	357808.RoseRS_4004	2.791e-127	419.0	COG4597@1|root,COG4597@2|Bacteria,2G7PM@200795|Chloroflexi,376AX@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
GDHHQS3_k127_3782596_1	357808.RoseRS_4005	6.471e-155	497.0	COG0834@1|root,COG0834@2|Bacteria,2G7RH@200795|Chloroflexi,376Y9@32061|Chloroflexia	32061|Chloroflexia	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
GDHHQS3_k127_3782596_5	926569.ANT_11330	6.731e-44	166.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS3_k127_3782596_0	926550.CLDAP_39810	4.99e-224	716.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GDHHQS3_k127_3782596_3	926569.ANT_16690	1.225e-112	376.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GDHHQS3_k127_3782596_9	1122939.ATUD01000001_gene243	1.294e-16	85.0	COG4243@1|root,COG4243@2|Bacteria,2HGRK@201174|Actinobacteria,4CSQE@84995|Rubrobacteria	84995|Rubrobacteria	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GDHHQS3_k127_3782596_4	326427.Cagg_2787	1.808e-61	220.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS3_k127_3782596_6	324602.Caur_2581	3.952e-35	138.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3782596_8	273068.TTE0540	2.38e-30	127.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,42F7H@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam abc	-	-	-	ko:K06158,ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000,ko03012	3.A.1.121	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_3788942_3	1089551.KE386572_gene1671	7.088e-05	48.0	COG0500@1|root,COG2226@2|Bacteria,1P9C1@1224|Proteobacteria,2U359@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_3788942_1	926569.ANT_15730	3.665e-85	296.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS3_k127_3788942_0	926569.ANT_15720	6.273e-155	501.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GDHHQS3_k127_3849287_4	926550.CLDAP_20840	5.155e-68	234.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_3849287_5	266117.Rxyl_2427	1.865e-54	200.0	2DBRF@1|root,2ZAKB@2|Bacteria,2IIVX@201174|Actinobacteria,4CQPW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3849287_9	5786.XP_003293034.1	3.409e-08	63.0	298Y8@1|root,2RFZH@2759|Eukaryota,3XFE2@554915|Amoebozoa	554915|Amoebozoa	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS3_k127_3849287_3	926569.ANT_15940	3.462e-76	269.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_3849287_1	926569.ANT_15930	4.058e-116	380.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GDHHQS3_k127_3849287_2	926569.ANT_15920	7.011e-91	308.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GDHHQS3_k127_3849287_0	706587.Desti_1075	0.0	1127.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS3_k127_3849287_7	926569.ANT_00160	2.125e-35	145.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3849287_6	439235.Dalk_1682	3.285e-48	184.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3851373_7	1089550.ATTH01000001_gene1187	3.68e-32	129.0	COG3339@1|root,COG3339@2|Bacteria,4NRQP@976|Bacteroidetes,1FK9F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GDHHQS3_k127_3851373_4	7668.SPU_027965-tr	4.136e-58	213.0	COG1028@1|root,KOG1208@2759|Eukaryota,38CZD@33154|Opisthokonta,3BACQ@33208|Metazoa,3CSEJ@33213|Bilateria	33208|Metazoa	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	RDH13	GO:0001523,GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0007275,GO:0007399,GO:0007423,GO:0008106,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009653,GO:0009887,GO:0009987,GO:0010817,GO:0010842,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0019866,GO:0022008,GO:0030154,GO:0030182,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0034308,GO:0034754,GO:0042445,GO:0042461,GO:0042462,GO:0042572,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046530,GO:0048468,GO:0048513,GO:0048592,GO:0048593,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0052650,GO:0055114,GO:0060041,GO:0060042,GO:0065007,GO:0065008,GO:0071704,GO:0090596,GO:1901615	1.1.1.300,2.3.2.27	ko:K04506,ko:K11153,ko:K11161	ko00830,ko01100,ko04013,ko04115,ko04120,ko04310,map00830,map01100,map04013,map04115,map04120,map04310	-	R08379,R08383	RC00649	ko00000,ko00001,ko01000,ko04121	-	-	-	adh_short
GDHHQS3_k127_3851373_5	1265310.CCBD010000007_gene3204	5.747e-40	158.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GDHHQS3_k127_3851373_8	269798.CHU_0641	1.305e-29	123.0	COG0454@1|root,COG0456@2|Bacteria,4NTZY@976|Bacteroidetes,47VBN@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_3851373_9	263358.VAB18032_24420	7.602e-29	129.0	2BNCX@1|root,32H0K@2|Bacteria,2H4ZP@201174|Actinobacteria,4DIXP@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3851373_2	479434.Sthe_2591	9.327e-67	242.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS3_k127_3851373_6	794846.AJQU01000076_gene256	2.808e-33	139.0	COG1247@1|root,COG1247@2|Bacteria,1QU6J@1224|Proteobacteria,2TW1P@28211|Alphaproteobacteria,4BNS3@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GDHHQS3_k127_3851373_10	1384049.CD29_11815	5.076e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3IYM2@400634|Lysinibacillus	91061|Bacilli	K	Cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_3851373_0	644282.Deba_0431	7.993e-169	549.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GDHHQS3_k127_3851373_3	1265505.ATUG01000001_gene4242	1.043e-62	227.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_3851373_1	7897.ENSLACP00000018513	6.736e-75	261.0	COG2301@1|root,2QQPK@2759|Eukaryota,38GJH@33154|Opisthokonta,3BAH3@33208|Metazoa,3CUC8@33213|Bilateria,482FQ@7711|Chordata,48Z08@7742|Vertebrata	33208|Metazoa	F	Citrate lyase subunit beta-like protein	CLYBL	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
GDHHQS3_k127_3851373_11	1128421.JAGA01000002_gene654	9.342e-09	63.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GDHHQS3_k127_3899192_1	1041930.Mtc_0315	1.28e-161	533.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2N9F3@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM CoA-binding domain protein	acdAB	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
GDHHQS3_k127_3899192_7	1049564.TevJSym_at00550	7.42e-69	243.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1J69D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S protein	ycbX	GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754	-	ko:K07140	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
GDHHQS3_k127_3899192_2	768671.ThimaDRAFT_1778	2.756e-131	427.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
GDHHQS3_k127_3899192_8	56780.SYN_02041	1.336e-63	226.0	28IYQ@1|root,2Z8WB@2|Bacteria,1MY3Q@1224|Proteobacteria	1224|Proteobacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
GDHHQS3_k127_3899192_4	1433126.BN938_2585	1.211e-127	413.0	COG0863@1|root,COG0863@2|Bacteria,4NID2@976|Bacteroidetes,2FV9W@200643|Bacteroidia	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS3_k127_3899192_3	926569.ANT_22600	2.051e-129	423.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GDHHQS3_k127_3899192_5	926569.ANT_22610	3.411e-122	400.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GDHHQS3_k127_3899192_0	926569.ANT_22620	3.57e-241	761.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi	200795|Chloroflexi	GM	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
GDHHQS3_k127_3899192_6	485916.Dtox_2855	1.002e-81	281.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,261N7@186807|Peptococcaceae	186801|Clostridia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_3899192_9	926569.ANT_22630	6.291e-62	217.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_3920154_15	1382306.JNIM01000001_gene4165	7.565e-21	105.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	XK27_10720	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GDHHQS3_k127_3920154_4	649638.Trad_2961	7.55e-169	543.0	COG0366@1|root,COG0366@2|Bacteria,1WIU5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
GDHHQS3_k127_3920154_6	357808.RoseRS_0014	8.224e-157	511.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,376G5@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS3_k127_3920154_9	1307761.L21SP2_2489	6.684e-106	352.0	COG3833@1|root,COG3833@2|Bacteria,2J6AB@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GDHHQS3_k127_3920154_12	1125973.JNLC01000009_gene197	9.991e-92	319.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria	1224|Proteobacteria	P	transport	malF	GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351	-	ko:K02025,ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	iZ_1308.Z5631	BPD_transp_1,MalF_P2
GDHHQS3_k127_3920154_11	926561.KB900617_gene2286	2.697e-94	324.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,247KG@186801|Clostridia,3WAB7@53433|Halanaerobiales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
GDHHQS3_k127_3920154_7	926569.ANT_11020	3.576e-139	454.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
GDHHQS3_k127_3920154_5	926569.ANT_20720	1.242e-168	536.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
GDHHQS3_k127_3920154_10	1499967.BAYZ01000095_gene4153	3.043e-95	325.0	COG0738@1|root,COG0738@2|Bacteria,2NQUK@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	araJ1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_3920154_8	42256.RradSPS_2897	2.705e-123	406.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4CRYS@84995|Rubrobacteria	84995|Rubrobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GDHHQS3_k127_3920154_3	926569.ANT_25420	8.093e-226	706.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GDHHQS3_k127_3920154_2	926569.ANT_25410	3.09e-267	831.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GDHHQS3_k127_3920154_14	926569.ANT_03760	5.431e-48	175.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GDHHQS3_k127_3920154_16	926569.ANT_20440	1.938e-19	95.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3920154_13	926569.ANT_20430	4.378e-71	244.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GDHHQS3_k127_3920154_1	324602.Caur_3096	5.628e-272	875.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,375DR@32061|Chloroflexia	32061|Chloroflexia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GDHHQS3_k127_3920154_0	926569.ANT_19970	3.2e-322	998.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GDHHQS3_k127_3920296_8	349161.Dred_1287	2.626e-29	122.0	COG1846@1|root,COG1846@2|Bacteria,1VVSW@1239|Firmicutes	1239|Firmicutes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GDHHQS3_k127_3920296_10	63737.Npun_R1197	5.753e-07	52.0	COG4422@1|root,COG4422@2|Bacteria,1G1Q2@1117|Cyanobacteria,1HNB4@1161|Nostocales	1117|Cyanobacteria	S	Phage Gp37Gp68 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_3920296_9	163908.KB235896_gene4768	3.515e-28	115.0	COG2361@1|root,COG2361@2|Bacteria,1G7E2@1117|Cyanobacteria,1HU2G@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_3920296_7	357808.RoseRS_0547	1.257e-29	121.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_3920296_6	593750.Metfor_0262	1.318e-50	181.0	COG1533@1|root,arCOG01290@2157|Archaea,2Y1RJ@28890|Euryarchaeota,2NAHF@224756|Methanomicrobia	224756|Methanomicrobia	L	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_3920296_0	926569.ANT_08730	0.0	1145.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
GDHHQS3_k127_3920296_11	1121377.KB906402_gene3344	1.046e-05	56.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_21,META
GDHHQS3_k127_3920296_1	926569.ANT_08710	1.129e-202	649.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GDHHQS3_k127_3920296_2	926569.ANT_09200	3.421e-173	559.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GDHHQS3_k127_3920296_4	926569.ANT_08300	5.296e-88	294.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_3920296_5	926569.ANT_08310	1.542e-52	195.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GDHHQS3_k127_3920296_3	926569.ANT_08320	1.278e-171	544.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_3955250_8	330214.NIDE2068	1.528e-19	90.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GDHHQS3_k127_3955250_5	1128421.JAGA01000002_gene949	3.488e-26	112.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_3955250_14	1032480.MLP_12630	0.0002151	48.0	COG2197@1|root,COG2197@2|Bacteria,2IFE7@201174|Actinobacteria,4DQ78@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_3955250_9	243230.DR_1710	8.68e-18	86.0	arCOG05253@1|root,31CTK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
GDHHQS3_k127_3955250_10	1123261.AXDW01000013_gene3529	2.522e-17	85.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1X8CX@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GDHHQS3_k127_3955250_7	1128421.JAGA01000002_gene949	3.466e-21	96.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GDHHQS3_k127_3955250_11	871968.DESME_01115	5.502e-11	68.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
GDHHQS3_k127_3955250_2	1129794.C427_4423	2.647e-38	154.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,DUF285,MucBP,SdrD_B
GDHHQS3_k127_3955250_12	926569.ANT_20470	1.602e-05	51.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS3_k127_3955250_4	1128421.JAGA01000003_gene2907	3.033e-30	131.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,LysM
GDHHQS3_k127_3955250_0	1499967.BAYZ01000038_gene2261	4.204e-101	332.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GDHHQS3_k127_3955250_1	1121918.ARWE01000001_gene1858	6.462e-42	176.0	COG2114@1|root,COG2114@2|Bacteria,1PFBZ@1224|Proteobacteria,439XJ@68525|delta/epsilon subdivisions,2X1UU@28221|Deltaproteobacteria,43VBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_3955250_15	1434325.AZQN01000001_gene519	0.000695	46.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,47SRN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
GDHHQS3_k127_3955250_3	234267.Acid_0752	3.267e-33	133.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_3955250_13	1254432.SCE1572_00115	2.119e-05	49.0	COG0776@1|root,COG0776@2|Bacteria,1N6FS@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
GDHHQS3_k127_3994898_4	1499967.BAYZ01000074_gene2137	1.725e-27	115.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_3994898_3	1499967.BAYZ01000074_gene2136	1.125e-34	137.0	COG1895@1|root,COG1895@2|Bacteria	2|Bacteria	O	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS3_k127_3994898_1	358681.BBR47_51080	1.036e-77	267.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,26RI0@186822|Paenibacillaceae	91061|Bacilli	E	generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GDHHQS3_k127_3994898_6	126957.SMAR015009-PA	1.354e-14	82.0	COG3340@1|root,2QR7X@2759|Eukaryota,39DGA@33154|Opisthokonta,3BC18@33208|Metazoa,3CWYN@33213|Bilateria,41WW9@6656|Arthropoda	33208|Metazoa	E	Serine-type peptidase activity. It is involved in the biological process described with proteolysis	-	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS3_k127_3994898_7	485913.Krac_6168	4.385e-10	67.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GDHHQS3_k127_3994898_2	319795.Dgeo_2415	1.561e-42	164.0	COG0346@1|root,COG0346@2|Bacteria,1WMJE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_3994898_0	926569.ANT_25840	1.276e-81	281.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GDHHQS3_k127_3994898_5	926569.ANT_25850	2.511e-15	80.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_4006571_6	926569.ANT_29070	1.347e-30	126.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_4006571_5	179408.Osc7112_3065	1.327e-35	137.0	2E46S@1|root,32Z2Q@2|Bacteria,1GA29@1117|Cyanobacteria,1HHD8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4006571_9	1121904.ARBP01000003_gene6210	0.0004328	50.0	2BW4G@1|root,2ZAQH@2|Bacteria,4NRKB@976|Bacteroidetes,47QKV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
GDHHQS3_k127_4006571_3	349521.HCH_03163	1.787e-75	263.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1XN82@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GDHHQS3_k127_4006571_0	1207076.ALAT01000030_gene43	1.692e-112	372.0	COG3938@1|root,COG3938@2|Bacteria,1NVF9@1224|Proteobacteria,1RRCW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the proline racemase family	-	GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
GDHHQS3_k127_4006571_2	1122604.JONR01000007_gene2940	3.134e-89	308.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1X3PM@135614|Xanthomonadales	135614|Xanthomonadales	E	acid dehydrogenase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_4006571_1	383372.Rcas_4096	1.124e-108	364.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,375GE@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_4006571_4	266117.Rxyl_0591	2.141e-39	154.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS3_k127_4006571_7	743722.Sph21_2082	5.809e-22	101.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_4115001_9	1121441.AUCX01000018_gene1493	1.897e-15	76.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GDHHQS3_k127_4115001_12	1347393.HG726019_gene7918	1.533e-06	53.0	293V0@1|root,2ZRA7@2|Bacteria,4P8QC@976|Bacteroidetes,2FVS2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4115001_5	926550.CLDAP_35390	5.569e-34	134.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS3_k127_4115001_1	926569.ANT_25160	1.201e-149	484.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_4115001_0	926569.ANT_25170	1.421e-157	507.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GDHHQS3_k127_4115001_4	926569.ANT_25180	1.067e-39	158.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4115001_2	926569.ANT_25190	3.507e-137	449.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_4115001_6	309807.SRU_2552	8.566e-18	88.0	2CDT8@1|root,33C3R@2|Bacteria,4NXI8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4115001_11	1192034.CAP_4615	9.893e-07	57.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_4115001_10	1151119.KB895497_gene3410	9.356e-09	63.0	COG3631@1|root,COG3631@2|Bacteria,2IFBE@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
GDHHQS3_k127_4115001_13	56107.Cylst_3965	0.0006972	44.0	COG2271@1|root,COG2271@2|Bacteria,1GJ1Q@1117|Cyanobacteria,1HSWX@1161|Nostocales	1117|Cyanobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_4115001_3	1131462.DCF50_p1222	1.301e-93	308.0	COG0842@1|root,COG0842@2|Bacteria,1TS7U@1239|Firmicutes,24E30@186801|Clostridia,264DK@186807|Peptococcaceae	186801|Clostridia	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_4162228_1	1501230.ET33_00530	6.711e-71	249.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,26TD7@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
GDHHQS3_k127_4162228_0	926569.ANT_00500	3.483e-135	443.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
GDHHQS3_k127_4162228_2	1382306.JNIM01000001_gene144	2.712e-27	119.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_416877_17	1150469.RSPPHO_03149	6.245e-06	49.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,2JP92@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_416877_3	926569.ANT_01830	7.199e-278	889.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GDHHQS3_k127_416877_12	593105.S7A_03895	1.856e-15	87.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,3VY6Y@53335|Pantoea	1236|Gammaproteobacteria	S	UPF0761 membrane protein	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GDHHQS3_k127_416877_4	926569.ANT_04770	5.498e-222	726.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
GDHHQS3_k127_416877_13	420246.GTNG_1737	1.812e-10	70.0	29Y0M@1|root,30JTI@2|Bacteria,1V50V@1239|Firmicutes,4HHX7@91061|Bacilli,1WES4@129337|Geobacillus	91061|Bacilli	S	Family of unknown function (DUF5317)	M1-582	-	-	-	-	-	-	-	-	-	-	-	DUF5317
GDHHQS3_k127_416877_7	485916.Dtox_2814	1.623e-122	409.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GDHHQS3_k127_416877_0	926569.ANT_25290	0.0	1458.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GDHHQS3_k127_416877_6	926569.ANT_05570	4.13e-125	409.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GDHHQS3_k127_416877_1	518766.Rmar_2084	0.0	1145.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1FIXV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GDHHQS3_k127_416877_11	555779.Dthio_PD0726	2.081e-16	85.0	2DMID@1|root,32RSF@2|Bacteria,1R0WM@1224|Proteobacteria,43D2G@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_416877_16	1043205.AFYF01000099_gene628	4.765e-06	50.0	COG4422@1|root,COG4422@2|Bacteria,2GJHQ@201174|Actinobacteria,4FJDI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_416877_14	314278.NB231_13616	1.875e-10	64.0	COG2336@1|root,COG2336@2|Bacteria,1NFRR@1224|Proteobacteria,1SRYR@1236|Gammaproteobacteria,1X1I7@135613|Chromatiales	135613|Chromatiales	T	Antitoxin	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	-
GDHHQS3_k127_416877_8	1173029.JH980292_gene325	5.083e-45	165.0	COG2337@1|root,COG2337@2|Bacteria,1G6KE@1117|Cyanobacteria,1HBJY@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS3_k127_416877_19	314607.KB13_1162	0.0002743	47.0	COG3391@1|root,COG3391@2|Bacteria,1MXJJ@1224|Proteobacteria,2VPSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
GDHHQS3_k127_416877_10	1499968.TCA2_3276	8.371e-26	119.0	COG1266@1|root,COG1266@2|Bacteria,1VWV1@1239|Firmicutes,4HXAX@91061|Bacilli,272WI@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS3_k127_416877_2	926569.ANT_15910	2.236e-295	916.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
GDHHQS3_k127_416877_9	926569.ANT_15900	4.569e-29	128.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_416877_5	326427.Cagg_2762	3.455e-130	424.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_4205100_6	1047013.AQSP01000144_gene895	7.826e-14	74.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GDHHQS3_k127_4205100_0	926569.ANT_15990	0.0	1099.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GDHHQS3_k127_4205100_1	926569.ANT_16000	2.1e-114	380.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi	200795|Chloroflexi	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GDHHQS3_k127_4205100_4	255470.cbdbA675	8.732e-26	110.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi,34CU9@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS3_k127_4205100_2	926569.ANT_16010	4.484e-92	308.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS3_k127_4205100_3	926569.ANT_16020	2.5e-49	184.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_4205100_5	926569.ANT_16030	1.59e-23	102.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS3_k127_4205100_8	1123388.AQWU01000045_gene1664	0.0001242	44.0	COG1837@1|root,COG1837@2|Bacteria,1WKGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS3_k127_4214420_0	926550.CLDAP_01130	6.496e-172	553.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_4214420_14	926569.ANT_29880	2.054e-53	192.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GDHHQS3_k127_4214420_19	926569.ANT_00330	7.801e-46	175.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_4214420_25	1210884.HG799463_gene10154	0.0009906	45.0	COG0457@1|root,COG0457@2|Bacteria,2J0KQ@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4214420_22	83406.HDN1F_34800	4.661e-15	80.0	2DSPU@1|root,33GZC@2|Bacteria,1NJ5W@1224|Proteobacteria,1SHAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GDHHQS3_k127_4214420_4	706587.Desti_2994	5.727e-101	339.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,430WX@68525|delta/epsilon subdivisions,2WW1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
GDHHQS3_k127_4214420_15	926569.ANT_22710	5.613e-53	194.0	COG2045@1|root,COG2045@2|Bacteria,2G8Z5@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ComB family	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
GDHHQS3_k127_4214420_16	926550.CLDAP_31610	6.782e-50	180.0	COG0720@1|root,COG0720@2|Bacteria,2G7B6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GDHHQS3_k127_4214420_6	1210908.HSB1_06020	8.761e-91	310.0	COG0438@1|root,arCOG01411@2157|Archaea,2XUFU@28890|Euryarchaeota,23U4A@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4214420_10	1366050.N234_05385	3.51e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,2VPJH@28216|Betaproteobacteria,1K0I0@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_4214420_9	926569.ANT_07880	6.404e-68	241.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
GDHHQS3_k127_4214420_1	383372.Rcas_0944	4.32e-143	466.0	COG0513@1|root,COG0513@2|Bacteria,2G7NJ@200795|Chloroflexi,377YZ@32061|Chloroflexia	32061|Chloroflexia	JKL	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
GDHHQS3_k127_4214420_3	215803.DB30_2061	2.577e-133	436.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2
GDHHQS3_k127_4214420_24	1487953.JMKF01000070_gene3361	1.018e-08	59.0	COG1598@1|root,COG1598@2|Bacteria,1G92J@1117|Cyanobacteria,1HCSG@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4214420_23	118161.KB235922_gene5767	2.452e-12	69.0	COG1724@1|root,COG1724@2|Bacteria,1G9BE@1117|Cyanobacteria,3VKJT@52604|Pleurocapsales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_4214420_21	1036674.A28LD_1242	5.858e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_4214420_2	926569.ANT_08530	3.083e-138	446.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_4214420_13	926569.ANT_08510	3.3e-54	196.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GDHHQS3_k127_4214420_5	765420.OSCT_1336	2.008e-96	322.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_4214420_18	926569.ANT_08490	6.745e-46	171.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GDHHQS3_k127_4214420_8	926569.ANT_08470	2.388e-68	248.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GDHHQS3_k127_4214420_20	443143.GM18_2333	2.283e-39	148.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,42VA0@68525|delta/epsilon subdivisions,2WS1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
GDHHQS3_k127_4214420_17	269799.Gmet_2491	3.023e-48	175.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,42QF1@68525|delta/epsilon subdivisions,2WSAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
GDHHQS3_k127_4214420_7	926569.ANT_08430	2.898e-82	282.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi	200795|Chloroflexi	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GDHHQS3_k127_4230003_0	247490.KSU1_C1426	2.501e-100	337.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
GDHHQS3_k127_4230003_4	926569.ANT_30450	3.594e-24	108.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4230003_1	926569.ANT_30440	3.111e-67	241.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GDHHQS3_k127_4230003_3	351160.RRC9	1.14e-31	131.0	COG1309@1|root,arCOG02643@2157|Archaea	2157|Archaea	K	PFAM regulatory protein TetR	-	-	-	ko:K03577,ko:K18939	-	M00647,M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_6,TetR_N
GDHHQS3_k127_4230003_2	1487921.DP68_07280	1.706e-36	148.0	COG1266@1|root,COG1266@2|Bacteria,1VXTB@1239|Firmicutes,24HAI@186801|Clostridia,36J1R@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_4230003_5	1034769.KB910518_gene3430	6.82e-05	47.0	COG0596@1|root,COG0596@2|Bacteria,1VEDI@1239|Firmicutes,4HQQ2@91061|Bacilli,26VR3@186822|Paenibacillaceae	91061|Bacilli	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_4256056_2	926569.ANT_01690	1.467e-59	209.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GDHHQS3_k127_4256056_7	945713.IALB_0400	4.776e-22	100.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	mutT	-	3.6.1.13,3.6.1.55,3.6.1.67	ko:K01515,ko:K03574,ko:K08310	ko00230,ko00790,map00230,map00790	M00126	R01054,R04638	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
GDHHQS3_k127_4256056_1	926569.ANT_01680	2.68e-225	709.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
GDHHQS3_k127_4256056_3	926569.ANT_31270	9.854e-41	168.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
GDHHQS3_k127_4256056_0	926569.ANT_31260	7.457e-232	725.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_4256056_5	439292.Bsel_0248	1.539e-29	123.0	COG0590@1|root,COG0590@2|Bacteria,1V4SB@1239|Firmicutes,4HHWY@91061|Bacilli	91061|Bacilli	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_4256056_9	926560.KE387027_gene552	2.325e-13	72.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
GDHHQS3_k127_4256056_6	215803.DB30_1757	2.08e-28	123.0	2ENZC@1|root,33GK8@2|Bacteria,1Q928@1224|Proteobacteria,437HP@68525|delta/epsilon subdivisions,2X2R8@28221|Deltaproteobacteria,2YVM5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4256056_4	340177.Cag_1180	8.366e-34	131.0	2E3EN@1|root,32YDN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_4256056_8	580331.Thit_2118	1.901e-19	91.0	2DPG5@1|root,331XR@2|Bacteria,1VIE4@1239|Firmicutes,24RIM@186801|Clostridia,42HBB@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_4292112_0	1242864.D187_001206	8.871e-147	478.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS3_k127_4292112_1	1242864.D187_001207	7.007e-135	436.0	2BVU5@1|root,2Z9FH@2|Bacteria,1R6RV@1224|Proteobacteria,435B2@68525|delta/epsilon subdivisions,2WZN8@28221|Deltaproteobacteria,2Z2ES@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4292112_2	1242864.D187_001208	1.43e-92	315.0	COG0515@1|root,COG0515@2|Bacteria,1RM69@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_430493_6	525904.Tter_0970	5.774e-26	109.0	COG4012@1|root,COG4012@2|Bacteria,2NQGT@2323|unclassified Bacteria	2|Bacteria	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
GDHHQS3_k127_430493_2	1499967.BAYZ01000161_gene384	9.183e-100	333.0	COG1814@1|root,COG1814@2|Bacteria,2NP4E@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GDHHQS3_k127_430493_3	1173021.ALWA01000039_gene1957	2.665e-59	216.0	COG0500@1|root,COG2226@2|Bacteria,1GC88@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_430493_0	926569.ANT_16800	2.261e-239	747.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GDHHQS3_k127_430493_1	926569.ANT_16790	2.045e-183	584.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GDHHQS3_k127_430493_4	926569.ANT_16780	3.092e-33	132.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_4325808_7	861208.AGROH133_09431	1.484e-05	53.0	COG2010@1|root,COG3468@1|root,COG4625@1|root,COG4733@1|root,COG5184@1|root,COG2010@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,1QU2X@1224|Proteobacteria,2U54N@28211|Alphaproteobacteria,4BB7H@82115|Rhizobiaceae	28211|Alphaproteobacteria	MU	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,fn3
GDHHQS3_k127_4325808_5	317936.Nos7107_2981	1.362e-19	89.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HSNE@1161|Nostocales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GDHHQS3_k127_4325808_6	65393.PCC7424_5049	6.455e-11	65.0	2C6B2@1|root,335GA@2|Bacteria,1GRBH@1117|Cyanobacteria,3KKV9@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4325808_3	118166.JH976537_gene2658	1.099e-28	118.0	COG2442@1|root,COG2442@2|Bacteria,1G71J@1117|Cyanobacteria,1HBSD@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_4325808_0	1173024.KI912148_gene4778	4.473e-44	163.0	COG4634@1|root,COG4634@2|Bacteria,1GKPU@1117|Cyanobacteria,1JMIS@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4325808_1	574087.Acear_1714	3.933e-37	146.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WATJ@53433|Halanaerobiales	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
GDHHQS3_k127_4325808_4	880073.Calab_0118	1.459e-26	119.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
GDHHQS3_k127_4325808_2	1028806.GGE_2093	1.715e-30	124.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1S8Z3@1236|Gammaproteobacteria,1Y91K@135625|Pasteurellales	135625|Pasteurellales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS3_k127_4325808_8	907348.TresaDRAFT_0106	0.000158	44.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2J5WJ@203691|Spirochaetes	203691|Spirochaetes	L	Eco57I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
GDHHQS3_k127_4368958_10	1524467.IV04_10245	7.449e-08	60.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,3ZZIM@613|Serratia	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_4368958_12	1123405.AUMM01000016_gene2437	0.0001185	49.0	COG4974@1|root,COG4974@2|Bacteria,1V425@1239|Firmicutes,4IQMN@91061|Bacilli	91061|Bacilli	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GDHHQS3_k127_4368958_1	68170.KL590509_gene11301	7.132e-124	411.0	COG2253@1|root,COG2253@2|Bacteria,2HCHT@201174|Actinobacteria,4EDI4@85010|Pseudonocardiales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_4368958_5	220664.PFL_2493	1.207e-23	114.0	2ARNE@1|root,31GZ4@2|Bacteria,1QENI@1224|Proteobacteria,1SIDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4368958_7	1380390.JIAT01000010_gene4173	2.196e-18	86.0	COG3677@1|root,COG3677@2|Bacteria,2HGBB@201174|Actinobacteria,4CTUD@84995|Rubrobacteria	84995|Rubrobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4368958_3	331869.BAL199_01364	7.628e-49	181.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
GDHHQS3_k127_4368958_4	1499967.BAYZ01000013_gene6440	1.726e-46	169.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GDHHQS3_k127_4368958_6	1499967.BAYZ01000013_gene6441	2.158e-22	100.0	COG2442@1|root,COG2442@2|Bacteria,2NRXV@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GDHHQS3_k127_4368958_13	1489678.RDMS_04880	0.0006693	43.0	COG4974@1|root,COG4974@2|Bacteria,1WKPJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
GDHHQS3_k127_4368958_2	1191523.MROS_1885	9.761e-64	227.0	COG0020@1|root,COG0020@2|Bacteria	2|Bacteria	I	transferase activity, transferring alkyl or aryl (other than methyl) groups	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GDHHQS3_k127_4368958_11	398767.Glov_3695	8.78e-07	60.0	COG0582@1|root,COG0582@2|Bacteria,1REP1@1224|Proteobacteria,42SFC@68525|delta/epsilon subdivisions,2WNY1@28221|Deltaproteobacteria,43UAI@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4368958_8	63737.Npun_F6043	1.357e-11	69.0	COG4715@1|root,COG4715@2|Bacteria,1G37G@1117|Cyanobacteria,1HQHD@1161|Nostocales	1117|Cyanobacteria	S	zinc finger, SWIM	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
GDHHQS3_k127_4368958_9	357808.RoseRS_2535	2.448e-11	68.0	2CAI9@1|root,32RRG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4368958_0	357808.RoseRS_1829	8.178e-168	534.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_4441895_5	926569.ANT_28920	1.056e-39	159.0	28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi	926569.ANT_28920|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4441895_3	304371.MCP_0966	6.601e-64	231.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GDHHQS3_k127_4441895_1	926569.ANT_30110	1.417e-75	262.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GDHHQS3_k127_4441895_6	926550.CLDAP_10230	4.018e-23	108.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
GDHHQS3_k127_4441895_2	926569.ANT_30120	1.985e-74	265.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_4441895_0	926569.ANT_30130	1.646e-102	343.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS3_k127_4441895_4	926569.ANT_30130	1.798e-62	228.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS3_k127_4441895_7	717606.PaecuDRAFT_0704	7.736e-08	54.0	COG4894@1|root,COG4894@2|Bacteria,1VUCV@1239|Firmicutes,4I6QC@91061|Bacilli,26U9X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4449253_6	926569.ANT_03990	2.643e-11	64.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi	200795|Chloroflexi	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	lacD	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS3_k127_4449253_3	926569.ANT_04000	6.133e-133	429.0	COG3868@1|root,COG3868@2|Bacteria	2|Bacteria	S	Glycoside-hydrolase family GH114	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
GDHHQS3_k127_4449253_0	926569.ANT_04010	1.273e-261	809.0	COG1486@1|root,COG1486@2|Bacteria,2G858@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS3_k127_4449253_4	926569.ANT_04020	2.513e-102	344.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_4449253_2	926569.ANT_04030	5.62e-133	429.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_4449253_1	926569.ANT_04040	4.881e-175	557.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_4449253_5	485913.Krac_3684	3.505e-59	211.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS3_k127_4479380_3	1521187.JPIM01000016_gene3688	1.464e-84	284.0	COG2077@1|root,COG2077@2|Bacteria,2G8IQ@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
GDHHQS3_k127_4479380_5	717231.Flexsi_0321	4.993e-43	162.0	COG2905@1|root,COG2905@2|Bacteria,2GGGX@200930|Deferribacteres	200930|Deferribacteres	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_4479380_1	479434.Sthe_3293	2.063e-181	580.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GDHHQS3_k127_4479380_2	485913.Krac_11676	1.261e-94	320.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Ornithine cyclodeaminase mu-crystallin	arcB	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GDHHQS3_k127_4479380_4	926569.ANT_16270	1.019e-83	291.0	COG2197@1|root,COG2204@1|root,COG2197@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	yhjB	GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_4479380_0	926569.ANT_16280	1.389e-198	642.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA_2
GDHHQS3_k127_4479380_6	1382356.JQMP01000003_gene1402	1.239e-06	52.0	COG1280@1|root,COG1280@2|Bacteria,2GBTW@200795|Chloroflexi,27ZC9@189775|Thermomicrobia	189775|Thermomicrobia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS3_k127_449048_9	485913.Krac_10749	1.737e-85	296.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS3_k127_449048_18	1206741.BAFX01000195_gene3684	1.178e-14	83.0	2EQPB@1|root,33I99@2|Bacteria,2IKF5@201174|Actinobacteria,4FVIR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_449048_19	1453496.AT03_15810	4.642e-08	60.0	COG2197@1|root,COG2197@2|Bacteria,1Q7GF@1224|Proteobacteria,1RWWU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	narP	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_449048_21	880072.Desac_2179	2.278e-06	57.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	-	-	-	-	-	-	-	-	-	-	-	-	AAA_12,AAA_24,AAA_25,DUF4011
GDHHQS3_k127_449048_20	880072.Desac_2172	1.519e-07	55.0	arCOG07300@1|root,2ZTGG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_449048_4	880072.Desac_2171	3.607e-119	409.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
GDHHQS3_k127_449048_2	329726.AM1_2464	2.688e-185	619.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	2|Bacteria	V	ABC-type multidrug transport system ATPase component	-	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
GDHHQS3_k127_449048_8	502025.Hoch_1167	1.193e-86	310.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0JR@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
GDHHQS3_k127_449048_11	502025.Hoch_1167	1.184e-74	274.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0JR@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
GDHHQS3_k127_449048_1	118161.KB235922_gene570	3.247e-249	819.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,Thioesterase,ketoacyl-synt
GDHHQS3_k127_449048_3	671143.DAMO_2121	3.032e-135	445.0	COG0635@1|root,COG2267@1|root,COG0635@2|Bacteria,COG2267@2|Bacteria,2NRGT@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4,Radical_SAM
GDHHQS3_k127_449048_0	211165.AJLN01000051_gene5004	4.918e-312	1011.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
GDHHQS3_k127_449048_7	1242864.D187_005409	3.728e-87	306.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_449048_5	1242864.D187_005409	8.86e-92	317.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_449048_6	1242864.D187_005409	2.101e-91	316.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_449048_10	1242864.D187_005409	3.617e-83	292.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GDHHQS3_k127_449048_13	880071.Fleli_3958	5.112e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,47MF7@768503|Cytophagia	976|Bacteroidetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_449048_16	27923.ML460813a-PA	5.107e-18	93.0	KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa	33208|Metazoa	S	ubiquitin binding	C6orf106	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,UBA_4
GDHHQS3_k127_449048_17	1125863.JAFN01000001_gene2355	1.003e-14	88.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_449048_12	1205753.A989_18195	2.854e-67	237.0	2ER45@1|root,33IPQ@2|Bacteria,1NIGK@1224|Proteobacteria,1SHNU@1236|Gammaproteobacteria,1X9WH@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_449048_14	316274.Haur_1699	2.143e-39	153.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GDHHQS3_k127_449048_15	665577.JH993790_gene3021	1.578e-28	117.0	COG5646@1|root,COG5646@2|Bacteria,2IMR2@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_4504105_6	1410620.SHLA_15c000190	7.298e-06	50.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,4B982@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_4504105_1	926550.CLDAP_25650	1.677e-101	338.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_4504105_5	981369.JQMJ01000004_gene1732	1.106e-24	113.0	COG4221@1|root,COG4221@2|Bacteria,2I2Z8@201174|Actinobacteria,2NF2P@228398|Streptacidiphilus	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_4504105_0	1254432.SCE1572_28920	1.434e-103	342.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
GDHHQS3_k127_4504105_3	572546.Arcpr_1054	1.527e-42	164.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,246XA@183980|Archaeoglobi	183980|Archaeoglobi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
GDHHQS3_k127_4504105_4	1242864.D187_010342	1.644e-30	125.0	COG1959@1|root,COG1959@2|Bacteria,1N1AX@1224|Proteobacteria,43DNW@68525|delta/epsilon subdivisions,2WT2X@28221|Deltaproteobacteria,2YVXJ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GDHHQS3_k127_4504105_2	926569.ANT_26640	1.026e-97	333.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS3_k127_4508504_3	926569.ANT_26640	6.225e-96	331.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS3_k127_4508504_4	926569.ANT_26640	6.35e-81	287.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GDHHQS3_k127_4508504_1	484770.UFO1_1183	2.487e-151	511.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_4508504_2	357808.RoseRS_3212	1.05e-98	346.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GDHHQS3_k127_4508504_5	926569.ANT_01140	9.879e-70	260.0	COG1136@1|root,COG1136@2|Bacteria,2G82B@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_4508504_7	1123073.KB899241_gene2285	6.451e-20	89.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1T7S9@1236|Gammaproteobacteria,1X9NA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_4508504_8	1123073.KB899241_gene2285	0.0001318	46.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1T7S9@1236|Gammaproteobacteria,1X9NA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_4508504_6	349521.HCH_01563	2.808e-30	129.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GDHHQS3_k127_4508504_0	1123073.KB899241_gene2285	1.87e-192	612.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1T7S9@1236|Gammaproteobacteria,1X9NA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_4511540_3	316274.Haur_2919	1.279e-46	178.0	COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi,3779V@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GDHHQS3_k127_4511540_0	926569.ANT_04210	1.066e-95	323.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GDHHQS3_k127_4511540_1	926569.ANT_12990	1.003e-73	256.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
GDHHQS3_k127_4526690_6	926569.ANT_04780	1.805e-26	111.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GDHHQS3_k127_4526690_2	926554.KI912671_gene170	5.018e-45	165.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	yffH	-	-	-	-	-	-	-	-	-	-	-	DUF4406
GDHHQS3_k127_4526690_0	926569.ANT_28320	0.0	1734.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
GDHHQS3_k127_4526690_1	867845.KI911784_gene1685	9.175e-133	432.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_4526690_3	926569.ANT_28280	9.565e-33	128.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS3_k127_4526690_4	926569.ANT_28280	3.394e-32	126.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GDHHQS3_k127_4526690_8	926569.ANT_28270	1.153e-16	81.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GDHHQS3_k127_4526690_7	463191.SSEG_10950	4.009e-18	84.0	2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4526690_9	936155.HFELIS_16070	6.896e-16	78.0	2AICC@1|root,318TJ@2|Bacteria,1Q0XM@1224|Proteobacteria,431XH@68525|delta/epsilon subdivisions,2YSDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4527556_6	357808.RoseRS_2972	2.202e-85	290.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_4527556_4	316274.Haur_0958	1.745e-138	452.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_4527556_0	316274.Haur_4394	3.635e-242	772.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GDHHQS3_k127_4527556_1	1128421.JAGA01000004_gene2618	7.751e-160	512.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_4527556_10	706587.Desti_5608	5.338e-21	98.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GDHHQS3_k127_4527556_5	671143.DAMO_3032	7.5e-96	321.0	COG0861@1|root,COG0861@2|Bacteria,2NQFQ@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
GDHHQS3_k127_4527556_7	926569.ANT_04930	2.181e-66	238.0	COG0083@1|root,COG0083@2|Bacteria,2G6MP@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GDHHQS3_k127_4527556_3	926569.ANT_04920	6.756e-152	489.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_4527556_11	686340.Metal_3571	1.191e-17	85.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS3_k127_4527556_9	686340.Metal_3571	1.022e-21	97.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS3_k127_4527556_13	1096546.WYO_4536	2.161e-08	66.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,1JTQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM cyclic nucleotide-binding	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
GDHHQS3_k127_4527556_8	686340.Metal_3574	1.8e-56	213.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RX1K@1236|Gammaproteobacteria,1XGJU@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_4527556_12	290400.Jann_1824	8.232e-10	61.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,2UFGT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	homolog of Blt101	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
GDHHQS3_k127_4527556_2	324602.Caur_3745	6.739e-153	496.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GDHHQS3_k127_4533598_7	485913.Krac_11000	2.004e-20	93.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5	-	-	DDE_Tnp_ISAZ013,Peripla_BP_3
GDHHQS3_k127_4533598_5	926550.CLDAP_05380	3.363e-34	138.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_4533598_6	1322246.BN4_11652	3.997e-25	105.0	COG4895@1|root,COG4895@2|Bacteria,1N7TD@1224|Proteobacteria,42V1D@68525|delta/epsilon subdivisions,2WRFN@28221|Deltaproteobacteria,2MDHS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
GDHHQS3_k127_4533598_3	926550.CLDAP_35170	3.974e-48	175.0	COG0346@1|root,COG0346@2|Bacteria,2G9TR@200795|Chloroflexi	200795|Chloroflexi	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_4533598_4	945713.IALB_0030	6.685e-43	168.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Methyltransf_11,Methyltransf_12,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_4533598_2	485913.Krac_4710	3.413e-105	356.0	COG0477@1|root,COG2814@2|Bacteria,2G7RU@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_4533598_0	383372.Rcas_1934	5.126e-315	977.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
GDHHQS3_k127_4533598_1	518766.Rmar_1606	2.623e-116	391.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
GDHHQS3_k127_4540484_0	926569.ANT_18150	1.47e-158	507.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS3_k127_4540484_1	926569.ANT_18160	1.352e-58	213.0	COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi	200795|Chloroflexi	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD
GDHHQS3_k127_4540484_2	696747.NIES39_Q00900	0.0003504	43.0	COG3335@1|root,COG3335@2|Bacteria,1GAQA@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS3_k127_4549391_6	102125.Xen7305DRAFT_00028620	2.265e-83	287.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,3VNMH@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GDHHQS3_k127_4549391_9	926550.CLDAP_21910	3.78e-59	208.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GDHHQS3_k127_4549391_13	1068980.ARVW01000001_gene4938	1.357e-09	64.0	COG0346@1|root,COG0346@2|Bacteria,2INT0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4549391_3	1185876.BN8_05913	7.616e-98	331.0	COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,47SZ6@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GDHHQS3_k127_4549391_4	330214.NIDE3954	1.535e-95	329.0	29G26@1|root,302ZX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4549391_8	926569.ANT_05880	1.227e-76	265.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GDHHQS3_k127_4549391_2	1128421.JAGA01000001_gene2047	1.571e-112	370.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GDHHQS3_k127_4549391_5	1121377.KB906398_gene2401	1.086e-86	309.0	COG2199@1|root,COG3706@2|Bacteria,1WI95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,GGDEF,HAMP,HisKA_7TM,PAS_4
GDHHQS3_k127_4549391_1	926569.ANT_24850	1.414e-161	518.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GDHHQS3_k127_4549391_10	1265505.ATUG01000002_gene2349	1.861e-57	214.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_4549391_11	926569.ANT_00160	1.143e-38	152.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4549391_0	706587.Desti_1075	0.0	1133.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GDHHQS3_k127_4549391_7	459349.CLOAM1351	1.131e-79	274.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
GDHHQS3_k127_455543_13	316274.Haur_2171	3.444e-22	97.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi,376D3@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_455543_6	926569.ANT_30070	3.467e-98	327.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GDHHQS3_k127_455543_9	926569.ANT_11900	8.805e-62	225.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GDHHQS3_k127_455543_7	926569.ANT_11910	1.738e-78	269.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GDHHQS3_k127_455543_3	926569.ANT_11930	4.57e-140	457.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GDHHQS3_k127_455543_12	926569.ANT_01860	3.432e-40	154.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GDHHQS3_k127_455543_2	926569.ANT_01870	4.535e-140	453.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS3_k127_455543_4	926569.ANT_01870	6.501e-134	434.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GDHHQS3_k127_455543_8	926569.ANT_01880	6.766e-66	235.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GDHHQS3_k127_455543_5	1120973.AQXL01000134_gene1554	6.516e-134	440.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GDHHQS3_k127_455543_11	1122223.KB890688_gene1782	1.442e-53	199.0	COG0169@1|root,COG0169@2|Bacteria,1WIM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
GDHHQS3_k127_455543_0	926569.ANT_01910	5.736e-169	540.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GDHHQS3_k127_455543_1	926569.ANT_01920	3.18e-146	479.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GDHHQS3_k127_455543_10	926569.ANT_29460	1.987e-56	200.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GDHHQS3_k127_455543_14	1392502.JNIO01000002_gene352	2.909e-13	70.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GDHHQS3_k127_4569223_1	926569.ANT_25330	1.259e-66	242.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GDHHQS3_k127_4569223_0	1380390.JIAT01000009_gene493	8.381e-195	620.0	COG1231@1|root,COG1231@2|Bacteria,2I8ZQ@201174|Actinobacteria,4CRBP@84995|Rubrobacteria	84995|Rubrobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GDHHQS3_k127_4569223_2	926569.ANT_25910	3.239e-34	134.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_4572377_0	760568.Desku_1514	8.597e-170	542.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_4572377_23	926569.ANT_17670	5.04e-34	136.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_27	926569.ANT_17670	9.091e-10	61.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_25	1123024.AUII01000009_gene2036	4.753e-32	132.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_4572377_19	1128421.JAGA01000001_gene2291	4.285e-37	146.0	COG3554@1|root,COG3554@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
GDHHQS3_k127_4572377_30	316274.Haur_4170	5.758e-08	61.0	COG4283@1|root,COG4283@2|Bacteria,2G9ST@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GDHHQS3_k127_4572377_5	485913.Krac_3074	3.708e-114	380.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GDHHQS3_k127_4572377_31	926550.CLDAP_23360	1.491e-05	57.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_4572377_16	326427.Cagg_2765	4.6e-52	203.0	COG0520@1|root,COG0520@2|Bacteria,2G7N0@200795|Chloroflexi,377HP@32061|Chloroflexia	32061|Chloroflexia	H	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_4572377_29	313606.M23134_03132	4.525e-08	66.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
GDHHQS3_k127_4572377_2	1223523.H340_07071	9.336e-136	456.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
GDHHQS3_k127_4572377_17	1033734.CAET01000041_gene402	3.692e-51	194.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_4572377_3	1173023.KE650771_gene4952	6.787e-132	436.0	COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.5.99.12	ko:K00279	ko00908,map00908	-	R05708	RC00121,RC01455	ko00000,ko00001,ko01000	-	-	-	Cytokin-bind,FAD_binding_4
GDHHQS3_k127_4572377_1	234267.Acid_0877	1.362e-147	489.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GDHHQS3_k127_4572377_21	926569.ANT_17670	2.032e-35	137.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_26	1128421.JAGA01000002_gene732	3.267e-18	84.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_7	479435.Kfla_4053	3.261e-94	323.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4DPVT@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
GDHHQS3_k127_4572377_8	340099.Teth39_0261	3.737e-85	297.0	COG2182@1|root,COG2182@2|Bacteria,1UI3N@1239|Firmicutes,25F4S@186801|Clostridia,42I09@68295|Thermoanaerobacterales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
GDHHQS3_k127_4572377_11	416591.Tlet_1227	5.713e-72	253.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10109,ko:K10118,ko:K15771,ko:K17242,ko:K17245	ko02010,map02010	M00194,M00196,M00198,M00207,M00491,M00600,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.28,3.A.1.1.3,3.A.1.1.39,3.A.1.1.40	-	-	BPD_transp_1
GDHHQS3_k127_4572377_10	1304865.JAGF01000001_gene1459	2.326e-74	259.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_4572377_9	1268072.PSAB_10605	4.034e-77	278.0	COG5297@1|root,COG5297@2|Bacteria,1UZ72@1239|Firmicutes,4HTY6@91061|Bacilli,26VE2@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 66	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Glyco_hydro_66
GDHHQS3_k127_4572377_6	1094508.Tsac_2301	2.678e-101	341.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,248Q3@186801|Clostridia	186801|Clostridia	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GDHHQS3_k127_4572377_22	292459.STH440	4.694e-34	150.0	COG3385@1|root,COG3385@2|Bacteria,1VJRW@1239|Firmicutes,24U4P@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
GDHHQS3_k127_4572377_18	765420.OSCT_0637	3.92e-43	160.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_28	926569.ANT_17670	1.381e-08	57.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4572377_12	867845.KI911784_gene1582	2.385e-66	233.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	M1-798	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
GDHHQS3_k127_4572377_24	948565.AFFP02000012_gene1799	1.758e-33	139.0	COG0500@1|root,COG2226@2|Bacteria,1NH38@1224|Proteobacteria,1RSAS@1236|Gammaproteobacteria,1Y7MV@135625|Pasteurellales	135625|Pasteurellales	Q	Mycolic acid cyclopropane synthetase	Z012_08625	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_4572377_13	1304878.AUGD01000003_gene2330	6.408e-62	221.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2U247@28211|Alphaproteobacteria,3JX9U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_4572377_4	1040986.ATYO01000012_gene5284	1.439e-127	421.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2TR2U@28211|Alphaproteobacteria,43NSP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_4572377_15	1123024.AUII01000052_gene3914	7.343e-56	202.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS3_k127_4582535_2	926569.ANT_25670	5.39e-93	317.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
GDHHQS3_k127_4582535_3	1131269.AQVV01000005_gene388	6.4e-49	196.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
GDHHQS3_k127_4582535_0	1307761.L21SP2_1483	4.68e-101	336.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
GDHHQS3_k127_4582535_4	946235.CAER01000069_gene2607	3.876e-38	156.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,23J3F@182709|Oceanobacillus	91061|Bacilli	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GDHHQS3_k127_4582535_1	926569.ANT_25680	2.099e-93	316.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS3_k127_4601314_1	1283300.ATXB01000002_gene2758	0.0	1303.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria,1XFZD@135618|Methylococcales	135618|Methylococcales	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
GDHHQS3_k127_4601314_3	247490.KSU1_D0536	4.542e-28	120.0	COG3772@1|root,COG3772@2|Bacteria	2|Bacteria	S	cytolysis by virus of host cell	-	-	3.2.1.17	ko:K01185,ko:K03791	-	-	-	-	ko00000,ko01000	-	GH19	-	DUF4231,Glyco_hydro_19,Peptidase_M15_3,Phage_lysozyme
GDHHQS3_k127_4601314_0	261292.Nit79A3_2482	0.0	2963.0	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,1QWX0@1224|Proteobacteria,2VSQ9@28216|Betaproteobacteria	28216|Betaproteobacteria	M	hydroxyisourate hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4601314_4	926569.ANT_17670	8.981e-11	63.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4601314_2	926569.ANT_17670	3.066e-127	417.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4605589_2	1118054.CAGW01000031_gene834	4.037e-07	55.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS3_k127_4605589_0	1382306.JNIM01000001_gene3678	2.366e-83	290.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
GDHHQS3_k127_4605589_1	338966.Ppro_1867	2.191e-52	191.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2X5QU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GDHHQS3_k127_4605589_3	247490.KSU1_B0193	2.439e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,Transglut_core2
GDHHQS3_k127_4610525_3	926569.ANT_02910	1.289e-136	446.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
GDHHQS3_k127_4610525_15	396588.Tgr7_1076	1.797e-38	146.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
GDHHQS3_k127_4610525_7	926569.ANT_12120	7.27e-81	284.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
GDHHQS3_k127_4610525_5	926569.ANT_12120	2.256e-91	314.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
GDHHQS3_k127_4610525_2	316274.Haur_3367	6.995e-191	600.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GDHHQS3_k127_4610525_12	1041930.Mtc_0845	4.04e-47	185.0	COG0642@1|root,arCOG02338@1|root,arCOG02338@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBMD@224756|Methanomicrobia	224756|Methanomicrobia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS3_k127_4610525_6	1463887.KL589954_gene7172	9.068e-83	289.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_4610525_4	926569.ANT_03360	1.99e-102	340.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
GDHHQS3_k127_4610525_0	485913.Krac_7358	3.267e-274	864.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_4610525_13	329726.AM1_2723	5.354e-42	157.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GDHHQS3_k127_4610525_9	868131.MSWAN_0340	9.375e-64	225.0	COG3832@1|root,arCOG05261@2157|Archaea,2XYEH@28890|Euryarchaeota	28890|Euryarchaeota	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_4610525_14	521011.Mpal_1109	2.592e-39	150.0	COG5646@1|root,arCOG09457@2157|Archaea,2Y6W7@28890|Euryarchaeota,2NAY6@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_4610525_10	1297742.A176_05793	1.233e-61	215.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria	1224|Proteobacteria	S	3-Demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GDHHQS3_k127_4610525_11	391037.Sare_2115	2.327e-48	178.0	COG3832@1|root,COG3832@2|Bacteria,2GQ4H@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_4610525_8	391037.Sare_2110	2.38e-80	274.0	COG4912@1|root,COG4912@2|Bacteria,2ID3C@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GDHHQS3_k127_4610525_1	886293.Sinac_4094	9.26e-207	647.0	COG0178@1|root,COG0178@2|Bacteria,2IYJN@203682|Planctomycetes	203682|Planctomycetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_462354_0	517418.Ctha_0130	4.307e-195	629.0	COG0247@1|root,COG0247@2|Bacteria,1FDTD@1090|Chlorobi	1090|Chlorobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
GDHHQS3_k127_462354_9	309801.trd_0145	5.112e-25	106.0	28XG9@1|root,2ZJDS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_462354_6	309801.trd_0144	6.473e-61	213.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_462354_7	309801.trd_0143	1.436e-54	194.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_462354_8	517418.Ctha_0129	5.166e-40	154.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GDHHQS3_k127_462354_2	517418.Ctha_0128	4.446e-126	415.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,DUF116
GDHHQS3_k127_462354_3	517418.Ctha_0127	9.905e-107	356.0	COG1856@1|root,COG1856@2|Bacteria	2|Bacteria	S	radical SAM domain protein	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
GDHHQS3_k127_462354_1	517418.Ctha_0126	1.01e-137	447.0	COG2516@1|root,COG2516@2|Bacteria	2|Bacteria	K	radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
GDHHQS3_k127_462354_4	517418.Ctha_0125	1.425e-94	320.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
GDHHQS3_k127_462354_5	1120973.AQXL01000129_gene2446	5.735e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_462354_10	324602.Caur_3202	2.127e-13	70.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi,376PA@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
GDHHQS3_k127_4625664_2	903818.KI912269_gene107	1.021e-63	228.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
GDHHQS3_k127_4625664_0	1121430.JMLG01000016_gene367	1.076e-205	661.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
GDHHQS3_k127_4625664_3	926550.CLDAP_19750	2.019e-08	59.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
GDHHQS3_k127_4625664_1	926569.ANT_01810	4.553e-111	368.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_4634842_0	649638.Trad_1980	2.781e-78	272.0	COG1609@1|root,COG1609@2|Bacteria,1WMBZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_4634842_1	1172180.KB911785_gene379	2.171e-18	89.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_4636986_0	383372.Rcas_3959	9.818e-114	376.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GDHHQS3_k127_4636986_7	102232.GLO73106DRAFT_00039380	3.659e-19	90.0	COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
GDHHQS3_k127_4636986_1	671143.DAMO_3092	2.233e-52	188.0	COG5499@1|root,COG5499@2|Bacteria,2NRMJ@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
GDHHQS3_k127_4636986_13	1150474.JQJI01000013_gene155	7.211e-09	60.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
GDHHQS3_k127_4636986_11	643648.Slip_1619	5.985e-13	74.0	COG1569@1|root,COG1569@2|Bacteria,1VKGG@1239|Firmicutes,24VUE@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_4636986_14	59931.WH7805_02872	9.793e-06	48.0	COG1694@1|root,COG1694@2|Bacteria,1GA07@1117|Cyanobacteria,1H0RK@1129|Synechococcus	1117|Cyanobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GDHHQS3_k127_4636986_9	383372.Rcas_2211	2.073e-16	80.0	2EP5I@1|root,33GS9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4636986_2	221288.JH992901_gene2648	1.443e-43	161.0	COG3654@1|root,COG3654@2|Bacteria,1G781@1117|Cyanobacteria,1JJ3W@1189|Stigonemataceae	1117|Cyanobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
GDHHQS3_k127_4636986_3	526227.Mesil_0390	1.247e-39	149.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GDHHQS3_k127_4636986_15	926550.CLDAP_28170	3.341e-05	57.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GDHHQS3_k127_4636986_10	324602.Caur_2814	4.646e-16	92.0	COG0642@1|root,COG2205@2|Bacteria,2G5YI@200795|Chloroflexi,37540@32061|Chloroflexia	32061|Chloroflexia	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GDHHQS3_k127_4636986_4	866895.HBHAL_4780	1.504e-35	149.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3ND4C@45667|Halobacillus	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
GDHHQS3_k127_4636986_8	138119.DSY1173	4.905e-19	96.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,24HNU@186801|Clostridia	186801|Clostridia	S	SNARE-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_4636986_6	335543.Sfum_3272	3.015e-22	106.0	COG0500@1|root,COG2226@2|Bacteria,1RKJ7@1224|Proteobacteria,42T77@68525|delta/epsilon subdivisions,2WT2E@28221|Deltaproteobacteria,2MS2J@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4636986_5	931626.Awo_c01040	3.602e-23	107.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,24HNU@186801|Clostridia,25WRN@186806|Eubacteriaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GDHHQS3_k127_4661703_10	1191523.MROS_2687	1.363e-21	100.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GDHHQS3_k127_4661703_0	269797.Mbar_A1244	1.248e-169	545.0	COG0520@1|root,arCOG00065@2157|Archaea	2157|Archaea	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GDHHQS3_k127_4661703_12	530564.Psta_4393	1.727e-15	83.0	COG3793@1|root,COG3793@2|Bacteria,2J4JH@203682|Planctomycetes	203682|Planctomycetes	P	zinc-ribbon family	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
GDHHQS3_k127_4661703_3	926569.ANT_13710	7.015e-103	342.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GDHHQS3_k127_4661703_7	357808.RoseRS_1596	1.1e-41	166.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GDHHQS3_k127_4661703_4	383372.Rcas_1082	5.96e-76	265.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
GDHHQS3_k127_4661703_1	926550.CLDAP_30340	8.936e-130	428.0	COG1721@1|root,COG1721@2|Bacteria,2G7PU@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_4661703_2	316274.Haur_0074	2.454e-124	406.0	COG0714@1|root,COG0714@2|Bacteria,2G85W@200795|Chloroflexi,3759A@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_4661703_9	926550.CLDAP_15460	5.94e-26	121.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
GDHHQS3_k127_4661703_8	1128421.JAGA01000002_gene1061	3.357e-31	135.0	2EQIM@1|root,33I4N@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
GDHHQS3_k127_4661703_14	1380390.JIAT01000009_gene1504	7.643e-07	61.0	COG4223@1|root,COG4223@2|Bacteria,2HQ3A@201174|Actinobacteria,4CRJT@84995|Rubrobacteria	84995|Rubrobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4661703_5	1128421.JAGA01000002_gene1167	1.542e-43	164.0	COG0801@1|root,COG0801@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
GDHHQS3_k127_4661703_6	926550.CLDAP_06330	3.27e-42	158.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GDHHQS3_k127_4663375_1	324602.Caur_3202	1.944e-195	623.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi,376PA@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
GDHHQS3_k127_4663375_0	926550.CLDAP_30470	0.0	1512.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GDHHQS3_k127_4663375_2	1128421.JAGA01000003_gene3171	1.434e-57	214.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
GDHHQS3_k127_4663375_3	515635.Dtur_1406	2.376e-11	75.0	COG1284@1|root,COG1284@2|Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
GDHHQS3_k127_4667806_0	452637.Oter_2238	1.192e-219	694.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GDHHQS3_k127_4667806_4	926569.ANT_20830	6.66e-105	352.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GDHHQS3_k127_4667806_9	604331.AUHY01000042_gene2025	1.944e-40	157.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS3_k127_4667806_3	926569.ANT_29590	2.61e-115	380.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GDHHQS3_k127_4667806_1	926569.ANT_20160	4.311e-177	561.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
GDHHQS3_k127_4667806_6	411479.BACUNI_02983	5.861e-58	213.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	1.1.1.384,2.6.1.102	ko:K13010,ko:K13327	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00801,M00802	R05526,R10460	RC00006,RC00781,RC00897	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_4667806_7	344747.PM8797T_27617	2.702e-56	203.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_4667806_8	314270.RB2083_3937	1.944e-54	199.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,2U32Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
GDHHQS3_k127_4667806_5	926569.ANT_20140	9.208e-91	307.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
GDHHQS3_k127_4667806_2	1120959.ATXF01000011_gene340	1.276e-171	555.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FKEP@85023|Microbacteriaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GDHHQS3_k127_4672587_4	926569.ANT_18610	4.647e-75	261.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
GDHHQS3_k127_4672587_2	926569.ANT_13730	3.283e-93	312.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GDHHQS3_k127_4672587_7	926569.ANT_13740	1.137e-52	190.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GDHHQS3_k127_4672587_3	700598.Niako_6181	2.175e-76	259.0	COG0847@1|root,COG0847@2|Bacteria,4NJMP@976|Bacteroidetes,1IX24@117747|Sphingobacteriia	976|Bacteroidetes	L	Exonuclease RNase T and DNA polymerase III	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051
GDHHQS3_k127_4672587_6	926569.ANT_13760	1.626e-64	226.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GDHHQS3_k127_4672587_19	267748.MMOB4980	1.545e-06	57.0	COG3557@1|root,COG3557@2|Bacteria,3WTPJ@544448|Tenericutes	544448|Tenericutes	J	domain protein associated with RNAses G and E	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GDHHQS3_k127_4672587_1	926569.ANT_16300	2.345e-108	358.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
GDHHQS3_k127_4672587_18	272134.KB731324_gene1337	3.43e-07	53.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS3_k127_4672587_12	272134.KB731324_gene1337	5.868e-31	126.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GDHHQS3_k127_4672587_5	203124.Tery_2637	7.135e-72	261.0	COG5305@1|root,COG5305@2|Bacteria,1G2NQ@1117|Cyanobacteria,1HEB9@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_4672587_11	373994.Riv7116_2250	1.617e-33	137.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GDHHQS3_k127_4672587_8	1237149.C900_00741	6.775e-45	169.0	COG1309@1|root,COG1309@2|Bacteria,4NPEQ@976|Bacteroidetes,47RWB@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GDHHQS3_k127_4672587_14	582744.Msip34_0922	2.525e-21	96.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,2VU4A@28216|Betaproteobacteria,2KN71@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
GDHHQS3_k127_4672587_9	1476973.JMMB01000007_gene1359	8.718e-43	172.0	2CG4J@1|root,33V86@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4672587_10	1303518.CCALI_02009	5.792e-38	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_4672587_17	591158.SSMG_05976	2.343e-07	60.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GDHHQS3_k127_4672587_16	326427.Cagg_3261	4.303e-08	65.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4672587_15	1122201.AUAZ01000001_gene2302	1.144e-08	58.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,468AF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GDHHQS3_k127_4672587_13	1089550.ATTH01000001_gene830	5.397e-22	98.0	2DQJV@1|root,337C3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GDHHQS3_k127_4672587_0	552811.Dehly_0399	3.113e-235	742.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_4679579_3	926569.ANT_22190	1.643e-54	208.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_4679579_4	672.VV93_v1c34210	2.032e-49	190.0	COG4763@1|root,COG4763@2|Bacteria,1QUH1@1224|Proteobacteria,1T1YM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS3_k127_4679579_1	926569.ANT_08420	1.236e-155	505.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GDHHQS3_k127_4679579_0	926569.ANT_08410	1.124e-205	650.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GDHHQS3_k127_4679579_2	926569.ANT_08400	2.493e-61	225.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_4698750_7	1128421.JAGA01000002_gene213	2.525e-06	49.0	COG3333@1|root,COG3333@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
GDHHQS3_k127_4698750_0	67257.JODR01000014_gene5811	4.189e-76	273.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_4698750_4	880073.Calab_1229	1.365e-28	122.0	COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin-like	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
GDHHQS3_k127_4698750_1	926569.ANT_12050	5.394e-76	261.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GDHHQS3_k127_4698750_5	926569.ANT_12030	4.341e-21	95.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GDHHQS3_k127_4698750_2	926569.ANT_12020	1.987e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GDHHQS3_k127_4698750_3	926569.ANT_28850	7.261e-53	190.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
GDHHQS3_k127_4700635_3	926569.ANT_26470	7.536e-52	191.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
GDHHQS3_k127_4700635_1	926569.ANT_26460	2.988e-73	254.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GDHHQS3_k127_4700635_4	1123368.AUIS01000006_gene626	8.009e-49	180.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
GDHHQS3_k127_4700635_5	926569.ANT_00590	1.155e-47	173.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GDHHQS3_k127_4700635_6	926569.ANT_00600	5.308e-24	105.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GDHHQS3_k127_4700635_2	926569.ANT_02480	5.167e-73	252.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GDHHQS3_k127_4700635_0	357808.RoseRS_0270	3.658e-100	355.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS3_k127_4708037_3	926569.ANT_07060	8.388e-23	105.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_4708037_6	1121121.KB894312_gene3241	0.0001846	44.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4708037_2	926569.ANT_06810	6.64e-66	231.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4708037_1	1128421.JAGA01000002_gene1836	7.183e-80	281.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
GDHHQS3_k127_4708037_0	926569.ANT_15760	1.273e-87	301.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GDHHQS3_k127_4708037_4	926569.ANT_29030	3.814e-20	93.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
GDHHQS3_k127_4718260_3	1329516.JPST01000014_gene497	7.374e-62	218.0	COG0281@1|root,COG0281@2|Bacteria,1UYHB@1239|Firmicutes,4HDRG@91061|Bacilli,27B6W@186824|Thermoactinomycetaceae	91061|Bacilli	C	Malic enzyme, N-terminal domain	mleA	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C,ACT_4,Malic_M,THF_DHG_CYH_C,malic
GDHHQS3_k127_4718260_0	926569.ANT_14860	1.368e-176	561.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GDHHQS3_k127_4718260_4	373903.Hore_13970	7.005e-38	148.0	COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes,24I7G@186801|Clostridia,3WAWF@53433|Halanaerobiales	186801|Clostridia	F	Belongs to the Nudix hydrolase family	-	-	-	ko:K12944	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
GDHHQS3_k127_4718260_5	1410620.SHLA_15c000190	4.83e-34	141.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,4B982@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_4718260_2	926550.CLDAP_25650	5.987e-87	297.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_4718260_1	926550.CLDAP_25650	5.559e-102	340.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_4728359_0	637910.ROD_47501	9.796e-131	429.0	COG4573@1|root,COG4573@2|Bacteria,1MW3Q@1224|Proteobacteria,1RQAU@1236|Gammaproteobacteria,3WWFG@544|Citrobacter	1236|Gammaproteobacteria	G	Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity	gatZ	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K02775,ko:K16371	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R01069,R05570	RC00017,RC00438,RC00439,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	iE2348C_1286.E2348C_2240,iECO111_1330.ECO111_2811,iECO26_1355.ECO26_3004,iYL1228.KPN_03547	Tagatose_6_P_K
GDHHQS3_k127_4728359_1	926569.ANT_03980	1.106e-120	397.0	COG0524@1|root,COG0524@2|Bacteria,2G6W1@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS3_k127_4728359_3	649638.Trad_0655	2.862e-68	246.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1
GDHHQS3_k127_4728359_2	926569.ANT_03990	6.386e-113	371.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi	200795|Chloroflexi	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	lacD	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
GDHHQS3_k127_4729465_2	926550.CLDAP_12350	1.182e-07	58.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GDHHQS3_k127_4729465_0	926550.CLDAP_27170	6.161e-127	419.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
GDHHQS3_k127_4729465_1	391625.PPSIR1_07178	7.867e-42	173.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
GDHHQS3_k127_4744534_9	1278073.MYSTI_05832	3.888e-58	207.0	COG4894@1|root,COG4894@2|Bacteria,1RKPJ@1224|Proteobacteria,434XW@68525|delta/epsilon subdivisions,2WZ8Q@28221|Deltaproteobacteria,2Z1KE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4744534_10	926569.ANT_30300	4.642e-56	198.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4744534_5	926569.ANT_00470	4.791e-100	331.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4744534_2	926569.ANT_02270	1.578e-198	638.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
GDHHQS3_k127_4744534_15	926569.ANT_02260	3.381e-33	131.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
GDHHQS3_k127_4744534_1	926569.ANT_02250	1.263e-252	791.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GDHHQS3_k127_4744534_13	926569.ANT_02240	2.729e-42	158.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GDHHQS3_k127_4744534_7	926569.ANT_02230	5.383e-93	315.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_4744534_3	926569.ANT_02220	5.482e-141	452.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
GDHHQS3_k127_4744534_8	357808.RoseRS_3756	3.54e-73	257.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GDHHQS3_k127_4744534_19	765420.OSCT_1252	3.3e-28	127.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi,3781H@32061|Chloroflexia	32061|Chloroflexia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GDHHQS3_k127_4744534_0	926569.ANT_14870	0.0	1283.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GDHHQS3_k127_4744534_26	402777.KB235904_gene4344	2.56e-21	103.0	COG1708@1|root,COG1708@2|Bacteria,1G8DN@1117|Cyanobacteria,1HC9X@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS3_k127_4744534_24	1499967.BAYZ01000170_gene5514	6.426e-22	97.0	2C6B2@1|root,335GA@2|Bacteria,2NRFZ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4744534_21	335541.Swol_0993	3.852e-27	126.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	-	-	2.1.1.113	ko:K00590,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HRDC,Mrr_N,Mrr_cat
GDHHQS3_k127_4744534_18	224911.27350373	3.194e-29	123.0	COG3703@1|root,COG3703@2|Bacteria,1NRIR@1224|Proteobacteria,2UPT4@28211|Alphaproteobacteria,3K35J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
GDHHQS3_k127_4744534_25	479434.Sthe_3271	2.393e-21	95.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_4744534_14	479434.Sthe_3272	2.876e-33	134.0	COG1848@1|root,COG1848@2|Bacteria,2G9NX@200795|Chloroflexi	200795|Chloroflexi	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_4744534_27	103690.17130612	1.327e-15	79.0	COG2852@1|root,COG2852@2|Bacteria,1G6SC@1117|Cyanobacteria,1HNXA@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
GDHHQS3_k127_4744534_29	1120968.AUBX01000010_gene1432	3.024e-05	47.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	leuS	-	3.1.26.4,6.1.1.4	ko:K01869,ko:K02500,ko:K03469	ko00340,ko00970,ko01100,ko01110,ko01230,ko03030,map00340,map00970,map01100,map01110,map01230,map03030	M00026,M00359,M00360	R03657,R04558	RC00010,RC00055,RC00523,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029,ko03032	-	-	-	DUF559
GDHHQS3_k127_4744534_20	357808.RoseRS_3688	3.203e-27	111.0	COG1598@1|root,COG1598@2|Bacteria,2G9PD@200795|Chloroflexi	200795|Chloroflexi	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_4744534_28	113355.CM001775_gene3409	3.635e-11	64.0	COG1724@1|root,COG1724@2|Bacteria,1G9BE@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_4744534_16	357808.RoseRS_4367	6.155e-31	123.0	2E828@1|root,332GA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4744534_17	1173027.Mic7113_5193	6.68e-30	121.0	COG1669@1|root,COG1669@2|Bacteria,1G6K9@1117|Cyanobacteria,1HCSN@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_4744534_22	195250.CM001776_gene1341	2.731e-24	104.0	COG2361@1|root,COG2361@2|Bacteria,1G80M@1117|Cyanobacteria,1H1W5@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_4744534_23	324057.Pjdr2_0238	4.146e-24	106.0	2CRSQ@1|root,32SPK@2|Bacteria,1VXRI@1239|Firmicutes,4HXIC@91061|Bacilli,26YPJ@186822|Paenibacillaceae	91061|Bacilli	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
GDHHQS3_k127_4744534_11	1460635.JCM19038_3982	2.578e-48	190.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
GDHHQS3_k127_4744534_4	383372.Rcas_0031	1.953e-114	390.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_4744534_6	926569.ANT_01760	1.692e-94	315.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_4744534_12	926569.ANT_01750	2.18e-44	170.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
GDHHQS3_k127_4753042_5	509635.N824_20250	4.891e-18	91.0	COG5646@1|root,COG5646@2|Bacteria,4NSVI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_4753042_6	1423321.AS29_09080	2.118e-14	80.0	2EGSG@1|root,33AIJ@2|Bacteria,1VMPG@1239|Firmicutes,4ITY8@91061|Bacilli,1ZJAN@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4753042_2	1123277.KB893180_gene2484	1.251e-158	512.0	COG2270@1|root,COG2270@2|Bacteria,4PN2C@976|Bacteroidetes,47NRP@768503|Cytophagia	976|Bacteroidetes	S	Major Facilitator Superfamily	-	-	-	ko:K18833	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.2	-	-	MFS_1
GDHHQS3_k127_4753042_3	153721.MYP_3119	3.357e-64	224.0	COG0262@1|root,COG0262@2|Bacteria,4NPX6@976|Bacteroidetes,47RPC@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
GDHHQS3_k127_4753042_4	526225.Gobs_3877	1.39e-47	176.0	COG0262@1|root,COG0262@2|Bacteria,2GQPJ@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_4753042_1	479434.Sthe_1273	1.715e-181	579.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GDHHQS3_k127_4753042_0	886293.Sinac_4094	1.563e-191	601.0	COG0178@1|root,COG0178@2|Bacteria,2IYJN@203682|Planctomycetes	203682|Planctomycetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GDHHQS3_k127_4767182_2	926569.ANT_23430	3.296e-145	468.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GDHHQS3_k127_4767182_6	926569.ANT_23420	2.654e-104	347.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GDHHQS3_k127_4767182_3	926569.ANT_23400	1.516e-144	473.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_4767182_5	926569.ANT_23380	3.201e-135	439.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GDHHQS3_k127_4767182_7	330214.NIDE0760	8.751e-63	231.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GDHHQS3_k127_4767182_1	926569.ANT_23360	2.945e-168	541.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_4767182_4	926569.ANT_23350	1.307e-141	457.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GDHHQS3_k127_4767182_0	926569.ANT_23340	2.237e-191	607.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GDHHQS3_k127_4767182_8	926569.ANT_23330	4.451e-38	145.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GDHHQS3_k127_4778063_2	266117.Rxyl_0743	6.792e-99	326.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GDHHQS3_k127_4778063_8	545695.TREAZ_1612	1.493e-25	108.0	COG1977@1|root,COG1977@2|Bacteria,2JATZ@203691|Spirochaetes	203691|Spirochaetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_4778063_4	331678.Cphamn1_1840	2.168e-74	254.0	COG2210@1|root,COG2210@2|Bacteria,1FE9Q@1090|Chlorobi	1090|Chlorobi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
GDHHQS3_k127_4778063_7	309801.trd_0160	2.388e-27	112.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
GDHHQS3_k127_4778063_6	1121904.ARBP01000019_gene2811	6.112e-29	120.0	COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,47RVG@768503|Cytophagia	976|Bacteroidetes	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GDHHQS3_k127_4778063_1	321327.CYA_1206	1.699e-108	361.0	COG0031@1|root,COG0031@2|Bacteria,1GBK3@1117|Cyanobacteria,1H00H@1129|Synechococcus	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_4778063_10	1122997.AUDD01000004_gene1331	3.735e-16	81.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
GDHHQS3_k127_4778063_0	926569.ANT_14030	1.475e-283	887.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GDHHQS3_k127_4778063_11	448385.sce8530	3.497e-06	51.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,2Z04N@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
GDHHQS3_k127_4778063_5	926569.ANT_10650	5.776e-44	167.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TPMT
GDHHQS3_k127_4778063_3	926550.CLDAP_34250	1.703e-76	267.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
GDHHQS3_k127_4778063_9	868131.MSWAN_1926	1.445e-23	112.0	COG1413@1|root,arCOG06468@1|root,arCOG02966@2157|Archaea,arCOG06468@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GDHHQS3_k127_4781442_17	1406840.Q763_00725	3.481e-21	104.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1I18E@117743|Flavobacteriia,2NTRS@237|Flavobacterium	976|Bacteroidetes	M	Glycoside hydrolase	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
GDHHQS3_k127_4781442_19	926569.ANT_20920	2.525e-11	68.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GDHHQS3_k127_4781442_10	926569.ANT_20930	1.49e-85	297.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_4781442_6	926569.ANT_13330	6.988e-133	432.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GDHHQS3_k127_4781442_12	926569.ANT_13320	1.711e-71	248.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
GDHHQS3_k127_4781442_16	1121920.AUAU01000017_gene1225	3.094e-24	108.0	COG0748@1|root,COG0748@2|Bacteria,3Y2Q3@57723|Acidobacteria	57723|Acidobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
GDHHQS3_k127_4781442_11	926560.KE387027_gene263	8.646e-83	283.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_4781442_7	926569.ANT_13310	5.097e-114	383.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
GDHHQS3_k127_4781442_1	1128421.JAGA01000003_gene3696	6.207e-196	628.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS3_k127_4781442_0	926569.ANT_13300	2.969e-199	632.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
GDHHQS3_k127_4781442_2	926550.CLDAP_19050	5.161e-178	567.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_4781442_8	926569.ANT_13270	4.996e-96	325.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_4781442_3	926569.ANT_13260	3.551e-161	519.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GDHHQS3_k127_4781442_5	1122223.KB890688_gene1840	1.129e-142	459.0	COG0057@1|root,COG0057@2|Bacteria,1WIAD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GDHHQS3_k127_4781442_4	926569.ANT_13240	1.611e-145	471.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GDHHQS3_k127_4781442_13	326427.Cagg_3772	1.276e-63	241.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GDHHQS3_k127_4781442_9	926569.ANT_19280	1.916e-88	298.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GDHHQS3_k127_4781442_14	926569.ANT_19290	8.163e-59	212.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4781442_18	243230.DR_1926	2.552e-17	93.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4796872_0	926569.ANT_15860	0.0	1054.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
GDHHQS3_k127_4796872_1	926569.ANT_15870	1.932e-175	576.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
GDHHQS3_k127_4796872_3	926569.ANT_15880	1.924e-85	292.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_4796872_2	324602.Caur_3475	2.994e-126	416.0	COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
GDHHQS3_k127_4800324_0	926569.ANT_11960	0.0	1110.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GDHHQS3_k127_4800324_3	525263.HMPREF0298_0367	0.0002087	53.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,22KGG@1653|Corynebacteriaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GDHHQS3_k127_4800324_2	1304878.AUGD01000006_gene6676	1.777e-35	154.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,2TSZG@28211|Alphaproteobacteria,3JU5Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_15725	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_4800324_1	926569.ANT_11950	6.257e-49	178.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS3_k127_4805537_5	926569.ANT_14390	6.151e-14	72.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_4805537_2	926569.ANT_14400	5.96e-87	293.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS3_k127_4805537_1	926569.ANT_14410	6.682e-95	317.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM F420-dependent oxidoreductase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
GDHHQS3_k127_4805537_4	797209.ZOD2009_16563	2.161e-30	124.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS3_k127_4805537_3	926550.CLDAP_12770	4.436e-57	208.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS3_k127_4805537_0	926569.ANT_14430	1.489e-112	372.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
GDHHQS3_k127_4810603_2	926550.CLDAP_38260	4.757e-157	512.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
GDHHQS3_k127_4810603_3	1047013.AQSP01000144_gene852	1.001e-25	111.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_4810603_1	926569.ANT_10670	4.489e-241	757.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,2G6PW@200795|Chloroflexi	200795|Chloroflexi	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,Dna2
GDHHQS3_k127_4810603_0	926569.ANT_10680	3.35e-249	784.0	COG0210@1|root,COG0210@2|Bacteria,2G69U@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase
GDHHQS3_k127_4823126_1	926569.ANT_16920	1.998e-198	626.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GDHHQS3_k127_4823126_6	926569.ANT_16930	3.061e-88	304.0	COG2234@1|root,COG2234@2|Bacteria,2G6WJ@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GDHHQS3_k127_4823126_4	926569.ANT_16940	5.802e-109	366.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_4823126_3	316274.Haur_2926	4.677e-136	446.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,375D2@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GDHHQS3_k127_4823126_9	926569.ANT_22580	7.974e-32	143.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_4823126_8	926569.ANT_22220	1.776e-48	179.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
GDHHQS3_k127_4823126_0	1191523.MROS_1372	4.548e-234	735.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
GDHHQS3_k127_4823126_2	1191523.MROS_1373	3.424e-143	464.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_4823126_5	1173028.ANKO01000139_gene671	3.856e-106	358.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GDHHQS3_k127_4823126_7	862515.HMPREF0658_0377	2.973e-75	263.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GDHHQS3_k127_4823126_10	926569.ANT_16980	2.527e-20	91.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GDHHQS3_k127_4836452_1	204669.Acid345_3109	1.954e-145	468.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS3_k127_4836452_3	1487953.JMKF01000016_gene2552	2.49e-44	164.0	COG2337@1|root,COG2337@2|Bacteria,1G5S4@1117|Cyanobacteria,1HBT3@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GDHHQS3_k127_4836452_5	870187.Thini_0498	1.075e-13	74.0	COG0864@1|root,COG0864@2|Bacteria,1NQ56@1224|Proteobacteria,1SH84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4836452_0	926569.ANT_10770	1.195e-172	554.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartokinase family	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
GDHHQS3_k127_4836452_2	926569.ANT_10760	1.591e-143	464.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_4836452_4	511062.GU3_13025	2.034e-17	85.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1Y44P@135624|Aeromonadales	135624|Aeromonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
GDHHQS3_k127_4842881_3	909663.KI867150_gene1647	5.581e-32	130.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,42PG1@68525|delta/epsilon subdivisions,2WP6V@28221|Deltaproteobacteria,2MRGQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
GDHHQS3_k127_4842881_1	1487923.DP73_21445	1.881e-77	269.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
GDHHQS3_k127_4842881_2	1121422.AUMW01000036_gene2699	6.172e-69	252.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,25ZZU@186807|Peptococcaceae	186801|Clostridia	C	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GDHHQS3_k127_4842881_6	667014.Thein_1161	1.243e-18	100.0	COG0685@1|root,COG0685@2|Bacteria,2GHGR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
GDHHQS3_k127_4842881_0	926569.ANT_28800	2.233e-141	458.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_4842881_4	1415775.U729_852	3.254e-25	115.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,36F9I@31979|Clostridiaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS3_k127_4842881_5	1128421.JAGA01000002_gene1976	9.654e-25	103.0	COG3458@1|root,COG3458@2|Bacteria,2NQIP@2323|unclassified Bacteria	2|Bacteria	Q	Acetyl xylan esterase (AXE1)	cah3	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
GDHHQS3_k127_4879483_4	219305.MCAG_02986	3.493e-05	50.0	COG0671@1|root,COG0671@2|Bacteria,2I92V@201174|Actinobacteria,4DF0B@85008|Micromonosporales	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GDHHQS3_k127_4879483_3	315749.Bcer98_2623	2.657e-06	52.0	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_4879483_0	485913.Krac_6882	1.336e-65	239.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
GDHHQS3_k127_4879483_2	485913.Krac_4421	1.992e-38	150.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS3_k127_4879483_1	272558.10174864	1.135e-56	207.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus	91061|Bacilli	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS3_k127_4882951_2	266835.14025719	2.378e-40	156.0	COG3464@1|root,COG4584@1|root,COG3464@2|Bacteria,COG4584@2|Bacteria,1N2KA@1224|Proteobacteria,2TVCT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
GDHHQS3_k127_4882951_0	926569.ANT_13120	6.413e-172	557.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GDHHQS3_k127_4882951_5	526227.Mesil_2630	5.945e-22	99.0	COG0607@1|root,COG0607@2|Bacteria,1WMYS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_4882951_1	1408226.T233_00945	5.278e-42	166.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,4B0P4@81852|Enterococcaceae	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GDHHQS3_k127_4882951_4	525904.Tter_0136	9.563e-30	132.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_4882951_6	1391647.AVSV01000028_gene248	1.214e-06	55.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GDHHQS3_k127_4889206_5	383372.Rcas_2861	9.499e-13	70.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_4889206_1	247490.KSU1_B0080	1.007e-26	110.0	2E3J3@1|root,32YHH@2|Bacteria,2J485@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4889206_2	247490.KSU1_B0079	2.33e-15	77.0	COG5428@1|root,COG5428@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
GDHHQS3_k127_4889206_3	926569.ANT_15080	1.056e-14	84.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_4889206_4	768670.Calni_1854	2.258e-13	71.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	hsdR_2	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
GDHHQS3_k127_4889206_0	768670.Calni_1406	3.674e-102	338.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	hsdR_2	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
GDHHQS3_k127_4901750_3	485913.Krac_3483	7.3e-82	277.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GDHHQS3_k127_4901750_1	926569.ANT_14120	9.153e-98	334.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	Acatn,MFS_1
GDHHQS3_k127_4901750_6	926569.ANT_18530	5.52e-52	187.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GDHHQS3_k127_4901750_4	443144.GM21_1138	8.541e-54	198.0	29FVD@1|root,302T2@2|Bacteria,1RKWC@1224|Proteobacteria,42TAZ@68525|delta/epsilon subdivisions,2WP8E@28221|Deltaproteobacteria,43T6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4901750_2	1521187.JPIM01000129_gene3616	3.472e-92	307.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,377EF@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_4901750_0	926569.ANT_24940	4.851e-297	928.0	COG1554@1|root,COG1554@2|Bacteria,2G5P0@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 65 central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
GDHHQS3_k127_4901750_8	867845.KI911784_gene742	1.369e-05	49.0	COG1554@1|root,COG1554@2|Bacteria,2G5P0@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 65 central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
GDHHQS3_k127_4901750_5	926569.ANT_18850	5.066e-53	188.0	COG2152@1|root,COG2152@2|Bacteria,2G6ZE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosidase PH1107-related	-	-	2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340	ko:K18785,ko:K20885	-	-	R10811,R10829,R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
GDHHQS3_k127_4901750_7	1366050.N234_09390	7.611e-06	51.0	COG3415@1|root,COG3415@2|Bacteria,1NB90@1224|Proteobacteria,2W6FF@28216|Betaproteobacteria,1KAC9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_33
GDHHQS3_k127_4901750_9	103733.JNYO01000117_gene2475	0.0005723	46.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria,4EBNV@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS3_k127_4945064_1	926569.ANT_29850	2.341e-107	371.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4945064_0	926569.ANT_27130	3.047e-139	451.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GDHHQS3_k127_4945064_2	386456.JQKN01000005_gene441	1.213e-71	250.0	arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GDHHQS3_k127_4945064_3	1504823.CCMM01000010_gene1220	7.276e-11	64.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GDHHQS3_k127_4948052_15	319003.Bra1253DRAFT_07750	1.201e-30	124.0	COG0451@1|root,COG0451@2|Bacteria,1NXWA@1224|Proteobacteria,2TVJJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,SPW,VKOR
GDHHQS3_k127_4948052_7	1088721.NSU_3039	3.408e-77	265.0	28JNX@1|root,2Z9F0@2|Bacteria,1RGTM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4948052_12	365044.Pnap_4549	6.516e-38	147.0	2CXGV@1|root,32T1Z@2|Bacteria,1N2KC@1224|Proteobacteria,2VVKZ@28216|Betaproteobacteria,4AEZZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4948052_21	869210.Marky_1036	1.558e-12	68.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_4948052_20	869210.Marky_1036	2.014e-15	77.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_4948052_23	178306.PAE2746	1.481e-09	60.0	COG3350@1|root,arCOG04507@2157|Archaea,2XR9V@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_4948052_16	644966.Tmar_1592	5.161e-27	114.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069,Lactamase_B,Rhodanese
GDHHQS3_k127_4948052_13	653733.Selin_1654	7.458e-35	143.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
GDHHQS3_k127_4948052_11	525904.Tter_0301	1.896e-44	181.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
GDHHQS3_k127_4948052_8	1128421.JAGA01000002_gene1308	1.429e-63	225.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_4948052_10	926550.CLDAP_14450	1.384e-46	177.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS3_k127_4948052_18	1173263.Syn7502_01511	3.862e-17	89.0	COG0515@1|root,COG0515@2|Bacteria,1GA6I@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
GDHHQS3_k127_4948052_24	1267535.KB906767_gene3192	5.779e-07	57.0	COG0845@1|root,COG0845@2|Bacteria,3Y49U@57723|Acidobacteria,2JM3N@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,YtkA
GDHHQS3_k127_4948052_5	1451261.AS96_04510	4.967e-97	328.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
GDHHQS3_k127_4948052_2	710696.Intca_3003	1.194e-123	407.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4FFD6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
GDHHQS3_k127_4948052_19	665571.STHERM_c14960	1.633e-16	85.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4948052_17	234267.Acid_6209	1.363e-25	113.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GDHHQS3_k127_4948052_4	926569.ANT_18500	1.29e-105	355.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GDHHQS3_k127_4948052_6	926569.ANT_23120	3.588e-86	294.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS3_k127_4948052_1	926569.ANT_12980	1.425e-207	679.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
GDHHQS3_k127_4948052_0	926569.ANT_11410	7.246e-233	739.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_4948052_9	1382306.JNIM01000001_gene466	9.582e-57	205.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_4948052_14	479433.Caci_0704	1.634e-33	138.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria	201174|Actinobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GDHHQS3_k127_4948052_3	926550.CLDAP_06710	2.263e-115	382.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS3_k127_4960084_26	402777.KB235903_gene1475	2.901e-19	95.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria,1H9TN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_4960084_27	562970.Btus_3191	5.561e-17	83.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GDHHQS3_k127_4960084_23	373994.Riv7116_6516	2.97e-42	159.0	COG1487@1|root,COG1487@2|Bacteria,1G63I@1117|Cyanobacteria,1HPWQ@1161|Nostocales	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GDHHQS3_k127_4960084_14	272134.KB731324_gene6348	1.485e-95	340.0	COG0457@1|root,COG0457@2|Bacteria,1G7YQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
GDHHQS3_k127_4960084_24	765420.OSCT_0637	1.87e-40	155.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4960084_28	926569.ANT_17670	6.764e-11	64.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_4960084_18	72019.SARC_01424T0	3.158e-66	231.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta	33154|Opisthokonta	F	IMP cyclohydrolase activity	ATIC	GO:0000003,GO:0003006,GO:0003360,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009108,GO:0009116,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009235,GO:0009259,GO:0009260,GO:0009396,GO:0009611,GO:0009653,GO:0009987,GO:0010035,GO:0015980,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0019953,GO:0021537,GO:0021543,GO:0021549,GO:0021987,GO:0022037,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0030900,GO:0030902,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0032505,GO:0033013,GO:0034293,GO:0034641,GO:0034654,GO:0042060,GO:0042221,GO:0042398,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045333,GO:0046040,GO:0046390,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046983,GO:0048468,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051186,GO:0051188,GO:0051321,GO:0051704,GO:0055086,GO:0055114,GO:0060322,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903046	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GDHHQS3_k127_4960084_19	1313172.YM304_23660	3.159e-65	228.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CNS4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GDHHQS3_k127_4960084_6	748727.CLJU_c22210	7.478e-165	528.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,36DHZ@31979|Clostridiaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
GDHHQS3_k127_4960084_1	5011.R4XGN3	1.081e-212	684.0	COG0151@1|root,KOG0237@2759|Eukaryota,38BPB@33154|Opisthokonta,3NXWQ@4751|Fungi,3QPMK@4890|Ascomycota,3MBQX@451866|Taphrinomycotina	4751|Fungi	F	Phosphoribosylamine-glycine ligase	ade1	GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YGL234W,iND750.YGL234W	AIRS,AIRS_C,GARS_A,GARS_C,GARS_N
GDHHQS3_k127_4960084_3	1313172.YM304_23690	2.77e-184	587.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CMWP@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
GDHHQS3_k127_4960084_21	243275.TDE_0687	2.864e-50	183.0	COG0041@1|root,COG0041@2|Bacteria,2J96B@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
GDHHQS3_k127_4960084_9	243275.TDE_0686	2.666e-138	447.0	COG0152@1|root,COG0152@2|Bacteria,2J6XZ@203691|Spirochaetes	203691|Spirochaetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
GDHHQS3_k127_4960084_15	243275.TDE_1405	2.931e-80	275.0	COG0047@1|root,COG0047@2|Bacteria,2J8JD@203691|Spirochaetes	203691|Spirochaetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	-	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GDHHQS3_k127_4960084_0	926550.CLDAP_05000	2.2e-306	966.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2G5Z1@200795|Chloroflexi	200795|Chloroflexi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
GDHHQS3_k127_4960084_25	926569.ANT_23680	4.299e-24	104.0	COG0140@1|root,COG0140@2|Bacteria,2G9QR@200795|Chloroflexi	200795|Chloroflexi	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
GDHHQS3_k127_4960084_22	1034345.CAEM01000014_gene142	3.129e-46	169.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CW3C@84998|Coriobacteriia	84998|Coriobacteriia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
GDHHQS3_k127_4960084_13	1158318.ATXC01000001_gene1314	2.85e-109	358.0	COG0107@1|root,COG0107@2|Bacteria,2G3N6@200783|Aquificae	200783|Aquificae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS3_k127_4960084_17	697281.Mahau_0268	3.968e-69	242.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,42G05@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GDHHQS3_k127_4960084_20	1089550.ATTH01000001_gene1415	7.003e-64	226.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1FJ7C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GDHHQS3_k127_4960084_16	926569.ANT_23730	1.831e-76	260.0	COG0131@1|root,COG0693@1|root,COG0131@2|Bacteria,COG0693@2|Bacteria,2G6JA@200795|Chloroflexi	200795|Chloroflexi	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
GDHHQS3_k127_4960084_10	926569.ANT_23740	6.472e-133	434.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_4960084_11	130081.XP_005706857.1	3.221e-130	429.0	COG0141@1|root,KOG2697@2759|Eukaryota	2759|Eukaryota	E	histidinol dehydrogenase activity	HIS4	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0009628,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0032501,GO:0032502,GO:0034641,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0048229,GO:0048856,GO:0050896,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,3.5.4.19,3.6.1.31	ko:K00013,ko:K14152	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012,R04035,R04037	RC00002,RC00099,RC00242,RC00463,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh,PRA-CH,PRA-PH
GDHHQS3_k127_4960084_8	926569.ANT_23760	5.096e-144	463.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
GDHHQS3_k127_4960084_2	926550.CLDAP_37900	1.104e-211	665.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_4960084_4	926550.CLDAP_37890	7.163e-182	580.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17312,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00604,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.15,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
GDHHQS3_k127_4960084_12	926550.CLDAP_37880	2.454e-124	406.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_4960084_5	926550.CLDAP_37870	9.638e-181	572.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	2|Bacteria	P	PFAM ABC transporter related	-	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
GDHHQS3_k127_4960084_7	518766.Rmar_1774	1.567e-150	485.0	COG1626@1|root,COG1626@2|Bacteria,4PKJT@976|Bacteroidetes	976|Bacteroidetes	G	glycoside hydrolase family 37	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GDHHQS3_k127_5088764_16	358681.BBR47_45130	1.08e-12	78.0	2DBAX@1|root,2Z84Q@2|Bacteria,1VHQG@1239|Firmicutes,4HPN3@91061|Bacilli,26X2H@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
GDHHQS3_k127_5088764_17	557598.LHK_01304	8.634e-09	58.0	COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,2VNQK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-ligase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
GDHHQS3_k127_5088764_15	1216966.BAUC01000002_gene2683	7.157e-14	77.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,1RQEG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
GDHHQS3_k127_5088764_19	926550.CLDAP_04930	0.0001222	46.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_5088764_4	1120746.CCNL01000008_gene852	3.673e-92	321.0	COG0371@1|root,COG0371@2|Bacteria	2|Bacteria	C	Dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
GDHHQS3_k127_5088764_5	926569.ANT_11860	2.349e-90	304.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
GDHHQS3_k127_5088764_2	903814.ELI_1847	9.865e-125	416.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25UR1@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_5088764_11	768672.Desfe_0774	2.084e-44	171.0	arCOG06048@1|root,arCOG06048@2157|Archaea,2XSAG@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5088764_3	1382306.JNIM01000001_gene2073	6.959e-95	322.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5088764_8	1131730.BAVI_09441	1.388e-69	257.0	COG0531@1|root,COG0531@2|Bacteria,1VZMY@1239|Firmicutes,4I0B0@91061|Bacilli	91061|Bacilli	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5088764_12	1382306.JNIM01000001_gene2925	5.073e-44	169.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GDHHQS3_k127_5088764_1	476272.RUMHYD_03636	4.97e-176	565.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,25M5K@186801|Clostridia,3Y1AP@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_5088764_13	476272.RUMHYD_03634	7.644e-29	119.0	2DVG6@1|root,33VR8@2|Bacteria,1VWC9@1239|Firmicutes,2510P@186801|Clostridia,3Y1S5@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_5088764_6	476272.RUMHYD_02343	2.746e-82	280.0	COG2070@1|root,COG2070@2|Bacteria,1VS86@1239|Firmicutes,25DQI@186801|Clostridia	186801|Clostridia	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5088764_18	27923.ML01833a-PA	1.964e-07	64.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa	2759|Eukaryota	S	Protein of unknown function (DUF2723)	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
GDHHQS3_k127_5088764_10	32057.KB217478_gene1994	5.97e-62	221.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HNDC@1161|Nostocales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GDHHQS3_k127_5088764_9	98439.AJLL01000052_gene3651	1.708e-62	227.0	COG3208@1|root,COG3208@2|Bacteria,1G16V@1117|Cyanobacteria,1JHZI@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
GDHHQS3_k127_5088764_0	880073.Calab_2572	0.0	2053.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria	2|Bacteria	Q	synthase	-	-	-	ko:K13611,ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,NAD_binding_4,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
GDHHQS3_k127_5088764_7	926569.ANT_18520	2.22e-77	265.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5088764_14	926569.ANT_29040	7.727e-20	91.0	COG3464@1|root,COG3464@2|Bacteria,2G9B1@200795|Chloroflexi	200795|Chloroflexi	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
GDHHQS3_k127_5093031_15	324602.Caur_1694	6.41e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,2GA74@200795|Chloroflexi,375MU@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5093031_14	391612.CY0110_15330	1.18e-13	73.0	2ERUP@1|root,33JDW@2|Bacteria,1GB8U@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5093031_9	28072.Nos7524_3317	1.668e-44	165.0	COG1569@1|root,COG1569@2|Bacteria,1G7US@1117|Cyanobacteria,1HNN8@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_5093031_4	1394178.AWOO02000004_gene2433	4.878e-95	318.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_5093031_8	485913.Krac_6390	1.413e-49	180.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_5093031_6	1313421.JHBV01000041_gene3598	1.739e-89	304.0	COG4638@1|root,COG4638@2|Bacteria,4NYTC@976|Bacteroidetes	976|Bacteroidetes	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GDHHQS3_k127_5093031_16	1111069.TCCBUS3UF1_p80	3.197e-07	60.0	COG1988@1|root,COG1988@2|Bacteria,1WJBJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GDHHQS3_k127_5093031_7	370438.PTH_1214	4.814e-55	212.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	dltB	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
GDHHQS3_k127_5093031_0	926569.ANT_12650	4.624e-291	903.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_5093031_11	1499680.CCFE01000031_gene3806	7.658e-27	112.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GDHHQS3_k127_5093031_2	525904.Tter_0058	2.568e-183	585.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GDHHQS3_k127_5093031_3	246194.CHY_1103	1.16e-153	499.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GDHHQS3_k127_5093031_13	1173028.ANKO01000083_gene927	2.785e-23	100.0	COG1598@1|root,COG1598@2|Bacteria,1G8YA@1117|Cyanobacteria,1HD7Z@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5093031_12	552811.Dehly_1441	6.876e-26	108.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_5093031_1	1121382.JQKG01000080_gene894	2.491e-240	768.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_5093031_5	1121382.JQKG01000080_gene895	8.139e-93	310.0	COG1136@1|root,COG1136@2|Bacteria,1WJ97@1297|Deinococcus-Thermus	2|Bacteria	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5093031_10	649639.Bcell_0815	1.374e-28	123.0	COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,4HJER@91061|Bacilli,1ZRHP@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator C-terminal region	XK27_03525	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS3_k127_5140403_1	316274.Haur_3660	1.174e-140	451.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
GDHHQS3_k127_5140403_0	1041146.ATZB01000003_gene6645	9.006e-152	489.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria,4B88V@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC-type xylose transport system, periplasmic component	chvE	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02058,ko:K10546	ko02010,map02010	M00216,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.5	-	-	Peripla_BP_4
GDHHQS3_k127_5140403_2	316274.Haur_3665	2.785e-92	314.0	COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia	2|Bacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_5140403_3	543632.JOJL01000113_gene8438	9.219e-74	257.0	COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5167005_3	926569.ANT_25500	1.003e-58	215.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5167005_0	557598.LHK_00777	4.101e-176	566.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KPJ8@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
GDHHQS3_k127_5167005_5	1254432.SCE1572_51315	1.346e-06	56.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2YW79@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GDHHQS3_k127_5167005_1	926569.ANT_25520	5.277e-80	270.0	COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi	200795|Chloroflexi	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_5167005_2	926569.ANT_02780	2.622e-63	224.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GDHHQS3_k127_5167005_4	926569.ANT_02790	9.53e-34	140.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
GDHHQS3_k127_5175580_6	797209.ZOD2009_21492	1.901e-25	120.0	COG1402@1|root,arCOG04536@2157|Archaea,2XWZU@28890|Euryarchaeota,23VFZ@183963|Halobacteria	183963|Halobacteria	H	protein, putative amidase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GDHHQS3_k127_5175580_3	383372.Rcas_0405	2.373e-107	360.0	COG3385@1|root,COG3385@2|Bacteria,2G8GC@200795|Chloroflexi,3768R@32061|Chloroflexia	32061|Chloroflexia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS3_k127_5175580_9	522306.CAP2UW1_0533	5.507e-11	66.0	2DNZI@1|root,32ZX6@2|Bacteria,1NKC7@1224|Proteobacteria,2W4U4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5175580_7	667014.Thein_1962	2.405e-16	82.0	arCOG07672@1|root,32Z5Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GDHHQS3_k127_5175580_0	1123242.JH636438_gene5740	1.047e-194	626.0	COG0210@1|root,COG1112@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,2IWV8@203682|Planctomycetes	203682|Planctomycetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,RNase_H_2
GDHHQS3_k127_5175580_5	867845.KI911784_gene1460	2.414e-33	139.0	COG0642@1|root,COG2205@2|Bacteria,2G84W@200795|Chloroflexi,3775F@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GDHHQS3_k127_5175580_1	1382306.JNIM01000001_gene2616	6.262e-159	521.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_5175580_2	316274.Haur_3626	8.367e-159	520.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_5175580_10	1121017.AUFG01000023_gene2161	7.699e-08	56.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4FHC8@85021|Intrasporangiaceae	201174|Actinobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GDHHQS3_k127_5175580_4	1304885.AUEY01000003_gene469	3.068e-88	296.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,42Q34@68525|delta/epsilon subdivisions,2WN9I@28221|Deltaproteobacteria,2MKB5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM formate nitrite transporter	fdhC	-	-	ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2	-	-	Form_Nir_trans,Response_reg
GDHHQS3_k127_5191336_4	316067.Geob_2072	8.925e-78	268.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
GDHHQS3_k127_5191336_3	1380347.JNII01000005_gene3050	2.153e-79	293.0	COG0446@1|root,COG0446@2|Bacteria,2GKQN@201174|Actinobacteria	201174|Actinobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GDHHQS3_k127_5191336_1	285535.JOEY01000006_gene8290	2.507e-149	501.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
GDHHQS3_k127_5191336_2	1123073.KB899241_gene2892	2.829e-134	444.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1X4VC@135614|Xanthomonadales	135614|Xanthomonadales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_5191336_0	1380394.JADL01000009_gene3326	8.675e-172	553.0	COG0531@1|root,COG0531@2|Bacteria,1MX13@1224|Proteobacteria,2U4NM@28211|Alphaproteobacteria,2JPBJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_5191336_5	107635.AZUO01000005_gene4217	1.651e-06	55.0	COG3464@1|root,COG3464@2|Bacteria,1QW5Z@1224|Proteobacteria,2U3N2@28211|Alphaproteobacteria,3708E@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS3_k127_5214950_3	765420.OSCT_2561	4.046e-14	80.0	COG0681@1|root,COG0681@2|Bacteria,2G85E@200795|Chloroflexi	200795|Chloroflexi	U	Family of unknown function (DUF5305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5305,Peptidase_S24
GDHHQS3_k127_5214950_2	926569.ANT_02840	1.1e-15	83.0	COG2931@1|root,COG2931@2|Bacteria,2G9JH@200795|Chloroflexi	200795|Chloroflexi	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
GDHHQS3_k127_5214950_1	926560.KE387023_gene2407	5.672e-36	142.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GDHHQS3_k127_5214950_0	794903.OPIT5_23600	1.246e-185	604.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
GDHHQS3_k127_5216466_2	926569.ANT_04640	4.349e-21	95.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5216466_1	926569.ANT_30350	7.852e-58	222.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5216466_0	926569.ANT_30340	1.532e-165	536.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_5251127_11	926550.CLDAP_00290	9.702e-45	165.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_5251127_5	1480694.DC28_05675	1.357e-157	502.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_5251127_2	926569.ANT_05060	1.153e-216	676.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GDHHQS3_k127_5251127_1	316274.Haur_3664	5.458e-239	748.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Arabinose_Iso_C,Arabinose_Isome
GDHHQS3_k127_5251127_9	926550.CLDAP_28240	4.11e-97	321.0	COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi	200795|Chloroflexi	G	Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
GDHHQS3_k127_5251127_0	926569.ANT_13670	7.118e-283	876.0	COG1069@1|root,COG1069@2|Bacteria,2G8AT@200795|Chloroflexi	200795|Chloroflexi	C	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_5251127_8	1304865.JAGF01000001_gene3272	6.991e-114	376.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_5251127_7	926569.ANT_13680	6.695e-120	395.0	COG0006@1|root,COG0006@2|Bacteria,2G6N9@200795|Chloroflexi	200795|Chloroflexi	E	Metallopeptidase family M24	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	Peptidase_M24
GDHHQS3_k127_5251127_4	1254432.SCE1572_49240	1.756e-161	513.0	COG0451@1|root,COG0451@2|Bacteria,1R456@1224|Proteobacteria	1224|Proteobacteria	GM	udp-glucose 4-epimerase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_5251127_3	614083.AWQR01000009_gene534	6.715e-177	561.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2VNI2@28216|Betaproteobacteria,4A9Y0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_5251127_10	936053.I1BXE1	4.272e-45	168.0	COG4702@1|root,2S03S@2759|Eukaryota,3A2EM@33154|Opisthokonta,3P3CR@4751|Fungi,1GU87@112252|Fungi incertae sedis	4751|Fungi	S	Haem-degrading	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006620,GO:0006810,GO:0006886,GO:0006996,GO:0007029,GO:0008104,GO:0008150,GO:0009987,GO:0010256,GO:0015031,GO:0015833,GO:0016043,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0061024,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071840,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090158	-	-	-	-	-	-	-	-	-	-	Haem_degrading
GDHHQS3_k127_5251127_6	1144319.PMI16_00908	6.467e-151	487.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2VKBB@28216|Betaproteobacteria,472UT@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	gguB	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
GDHHQS3_k127_5251127_12	316274.Haur_3660	1.675e-30	121.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
GDHHQS3_k127_5324588_18	349521.HCH_02502	2.374e-07	58.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM,Methyltransf_19
GDHHQS3_k127_5324588_17	324602.Caur_0018	1.772e-07	54.0	COG3315@1|root,COG3315@2|Bacteria,2GAE5@200795|Chloroflexi,375R6@32061|Chloroflexia	32061|Chloroflexia	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
GDHHQS3_k127_5324588_16	1157634.KB912999_gene4757	3.181e-12	70.0	COG2890@1|root,COG2890@2|Bacteria,2GITA@201174|Actinobacteria	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
GDHHQS3_k127_5324588_1	926569.ANT_16100	3.738e-205	649.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GDHHQS3_k127_5324588_8	926550.CLDAP_16260	3.727e-45	173.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
GDHHQS3_k127_5324588_0	926550.CLDAP_14400	1.133e-296	928.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
GDHHQS3_k127_5324588_5	326427.Cagg_1787	2.489e-85	297.0	COG0477@1|root,COG2814@2|Bacteria,2G7NY@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_5324588_14	926569.ANT_28110	9.772e-22	97.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GDHHQS3_k127_5324588_15	926569.ANT_01080	1.163e-12	69.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GDHHQS3_k127_5324588_2	926569.ANT_01090	4.662e-165	523.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi	200795|Chloroflexi	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GDHHQS3_k127_5324588_6	926569.ANT_09390	3.908e-56	199.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GDHHQS3_k127_5324588_10	1449069.JMLO01000016_gene3394	2.105e-38	149.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4G9EE@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_5324588_11	926569.ANT_08190	3.437e-27	111.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_5324588_9	926569.ANT_09400	1.773e-38	153.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GDHHQS3_k127_5324588_3	345219.Bcoa_0790	1.985e-153	494.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,1ZB0F@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GDHHQS3_k127_5324588_12	1122915.AUGY01000011_gene3989	8.983e-26	113.0	2EGE1@1|root,33A5Y@2|Bacteria,1VV4C@1239|Firmicutes,4HVGE@91061|Bacilli,26YKG@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5324588_13	268407.PWYN_19585	8.866e-24	103.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HWXY@91061|Bacilli,2704G@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GDHHQS3_k127_5324588_7	562743.JH976434_gene1836	4.971e-53	194.0	2DBV7@1|root,2ZB9P@2|Bacteria,1UBN2@1239|Firmicutes,4HEYF@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_5324588_4	1403313.AXBR01000005_gene1956	9.462e-112	370.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GDHHQS3_k127_5379723_3	926569.ANT_25040	4.828e-152	488.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GDHHQS3_k127_5379723_0	926569.ANT_25050	1.703e-309	959.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GDHHQS3_k127_5379723_12	926569.ANT_25060	1.905e-36	145.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GDHHQS3_k127_5379723_5	926569.ANT_25070	3.769e-122	400.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GDHHQS3_k127_5379723_2	926569.ANT_22580	2.701e-173	567.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GDHHQS3_k127_5379723_9	926569.ANT_23660	7.486e-75	263.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS3_k127_5379723_6	926569.ANT_23650	1.01e-114	399.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
GDHHQS3_k127_5379723_1	926569.ANT_23640	1.798e-175	568.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
GDHHQS3_k127_5379723_7	765420.OSCT_1016	1.167e-88	304.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GDHHQS3_k127_5379723_8	926569.ANT_16140	7.034e-75	264.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GDHHQS3_k127_5379723_10	1434325.AZQN01000003_gene1932	8.711e-73	249.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,47PXB@768503|Cytophagia	976|Bacteroidetes	L	PFAM methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GDHHQS3_k127_5379723_4	926569.ANT_04000	3.585e-123	401.0	COG3868@1|root,COG3868@2|Bacteria	2|Bacteria	S	Glycoside-hydrolase family GH114	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
GDHHQS3_k127_5379723_14	926550.CLDAP_25090	1.139e-32	134.0	COG0454@1|root,COG0456@2|Bacteria,2G95N@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GDHHQS3_k127_5379723_13	755731.Clo1100_2170	9.036e-33	140.0	COG3613@1|root,COG3613@2|Bacteria,1VKAC@1239|Firmicutes,24STX@186801|Clostridia,36MPX@31979|Clostridiaceae	186801|Clostridia	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5379723_11	518766.Rmar_1893	3.252e-41	154.0	COG0006@1|root,COG0006@2|Bacteria,4NJI0@976|Bacteroidetes,1FIUI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_540593_3	251221.35214034	5.18e-41	156.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_540593_2	357808.RoseRS_0549	1.513e-48	178.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GDHHQS3_k127_540593_0	926569.ANT_16050	1.098e-197	626.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS3_k127_540593_1	1519464.HY22_14040	2.689e-67	235.0	COG2270@1|root,COG2270@2|Bacteria,1FDCC@1090|Chlorobi	1090|Chlorobi	S	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
GDHHQS3_k127_5414571_1	926569.ANT_04720	1.551e-199	629.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
GDHHQS3_k127_5414571_0	926569.ANT_04710	4.972e-215	681.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS3_k127_5414571_4	926569.ANT_04700	8.913e-164	523.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_5414571_3	926569.ANT_04690	5.901e-166	527.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_5414571_8	1313172.YM304_01550	4.194e-100	338.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_5414571_7	1313172.YM304_01540	4.491e-105	349.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_5414571_6	1313172.YM304_01530	8.891e-110	365.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
GDHHQS3_k127_5414571_2	1120973.AQXL01000113_gene758	5.097e-167	539.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,27882@186823|Alicyclobacillaceae	91061|Bacilli	S	ABC transporter	mglA	-	3.6.3.17	ko:K02056,ko:K06400	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS3_k127_5414571_9	926569.ANT_14800	2.761e-86	294.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_5414571_5	926569.ANT_14810	1.445e-125	412.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GDHHQS3_k127_5573283_31	306281.AJLK01000101_gene3315	3.446e-23	104.0	2E1PV@1|root,32X09@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_5	880073.Calab_1023	3.515e-95	319.0	28MZ6@1|root,2ZB60@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_17	926569.ANT_27850	2.471e-43	166.0	COG3428@1|root,COG3428@2|Bacteria,2G9MG@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_12	1552758.NC00_06480	8.816e-70	249.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1X495@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
GDHHQS3_k127_5573283_21	324602.Caur_1958	3.717e-38	146.0	2E3MN@1|root,302XP@2|Bacteria,2G95X@200795|Chloroflexi,377TT@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_24	926550.CLDAP_07260	1.486e-37	146.0	2E3MN@1|root,32YJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_6	518766.Rmar_2285	9.032e-87	299.0	COG4243@1|root,COG4243@2|Bacteria,4PJI6@976|Bacteroidetes,1FK8W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_13	479434.Sthe_3401	6.578e-64	227.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GDHHQS3_k127_5573283_19	1172179.AUKV01000009_gene4532	2.948e-41	157.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS3_k127_5573283_25	1304885.AUEY01000016_gene3027	1.049e-36	142.0	COG0346@1|root,COG0346@2|Bacteria,1N57W@1224|Proteobacteria,439GC@68525|delta/epsilon subdivisions,2X4SB@28221|Deltaproteobacteria,2MM5J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
GDHHQS3_k127_5573283_22	742159.HMPREF0004_3229	5.093e-38	163.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,3T2EM@506|Alcaligenaceae	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
GDHHQS3_k127_5573283_14	479434.Sthe_0243	2.561e-60	216.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_5573283_29	365044.Pnap_0159	1.245e-24	107.0	2E75R@1|root,331PX@2|Bacteria,1NAGT@1224|Proteobacteria,2W4DV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_33	1120956.JHZK01000001_gene3395	8.112e-21	104.0	2C5N8@1|root,33T7S@2|Bacteria,1NRCN@1224|Proteobacteria,2UN4U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_32	1293048.CBMB010000010_gene3725	2.327e-22	108.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02556@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria	183963|Halobacteria	S	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GDHHQS3_k127_5573283_10	323098.Nwi_0773	5.01e-76	264.0	COG2010@1|root,COG2010@2|Bacteria,1MYNE@1224|Proteobacteria,2V9Z1@28211|Alphaproteobacteria,3K5DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GDHHQS3_k127_5573283_0	323098.Nwi_0774	0.0	1903.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria,3JVHG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	narZ	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
GDHHQS3_k127_5573283_1	671143.DAMO_0776	1.041e-247	772.0	COG1140@1|root,COG1140@2|Bacteria,2NQZJ@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
GDHHQS3_k127_5573283_30	323097.Nham_3446	3.26e-23	108.0	COG2180@1|root,COG2180@2|Bacteria,1NBVT@1224|Proteobacteria	1224|Proteobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
GDHHQS3_k127_5573283_9	323097.Nham_3445	1.015e-77	267.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2TTDB@28211|Alphaproteobacteria,3JWMR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
GDHHQS3_k127_5573283_38	649639.Bcell_2784	1.142e-09	65.0	COG3945@1|root,COG3945@2|Bacteria,1UJFW@1239|Firmicutes,4IT8J@91061|Bacilli	91061|Bacilli	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GDHHQS3_k127_5573283_11	867845.KI911784_gene2784	1.947e-70	245.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia	32061|Chloroflexia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
GDHHQS3_k127_5573283_4	616991.JPOO01000003_gene1695	1.66e-113	376.0	COG1275@1|root,COG1275@2|Bacteria,4NDUE@976|Bacteroidetes,1I1QS@117743|Flavobacteriia	976|Bacteroidetes	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
GDHHQS3_k127_5573283_39	485913.Krac_6994	2.288e-08	64.0	COG3507@1|root,COG3507@2|Bacteria,2G9A8@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
GDHHQS3_k127_5573283_28	483219.LILAB_34170	8.488e-25	108.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria	1224|Proteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS3_k127_5573283_16	1297569.MESS2_1220011	3.353e-46	171.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,2UC92@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
GDHHQS3_k127_5573283_37	479431.Namu_0476	3.516e-13	76.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESP4@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
GDHHQS3_k127_5573283_18	485913.Krac_6882	8.356e-43	168.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
GDHHQS3_k127_5573283_23	316058.RPB_1950	1.249e-37	147.0	2F9XY@1|root,34278@2|Bacteria,1NZDW@1224|Proteobacteria,2UTVM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_26	340177.Cag_1311	5.144e-34	131.0	COG4226@1|root,COG4226@2|Bacteria	2|Bacteria	K	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
GDHHQS3_k127_5573283_20	555779.Dthio_PD3774	1.178e-39	152.0	COG1569@1|root,COG1569@2|Bacteria,1N1T4@1224|Proteobacteria	1224|Proteobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_5573283_40	400682.PAC_15709646	4.946e-08	55.0	COG1995@1|root,2S0SC@2759|Eukaryota,3AAVQ@33154|Opisthokonta,3BY1M@33208|Metazoa	33208|Metazoa	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	-	-	-	-	-	-	-	-	-	-	PdxA
GDHHQS3_k127_5573283_36	1128421.JAGA01000002_gene732	3.553e-16	81.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_5573283_27	479434.Sthe_2726	1.251e-25	109.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_5573283_35	1183438.GKIL_2486	1.45e-19	94.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5573283_8	926569.ANT_30490	6.62e-78	269.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GDHHQS3_k127_5573283_15	864051.BurJ1DRAFT_3878	8.883e-55	207.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
GDHHQS3_k127_5573283_7	926569.ANT_30220	7.452e-86	289.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	devR	GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02479,ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_5573283_3	926569.ANT_30210	5.589e-120	400.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS3_k127_5573283_2	338969.Rfer_0358	1.957e-125	407.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_5620079_16	485913.Krac_4964	1.141e-09	64.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
GDHHQS3_k127_5620079_13	485913.Krac_10749	5.784e-35	139.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
GDHHQS3_k127_5620079_12	938709.AUSH02000030_gene1385	7.337e-43	159.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
GDHHQS3_k127_5620079_0	926550.CLDAP_10200	4.663e-193	612.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_5620079_6	926550.CLDAP_10190	1.679e-130	423.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_5620079_4	926550.CLDAP_10180	7.91e-145	466.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_5620079_10	1173026.Glo7428_1028	4.07e-66	230.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GDHHQS3_k127_5620079_7	525904.Tter_0164	3.851e-103	343.0	COG1940@1|root,COG1940@2|Bacteria,2NQJS@2323|unclassified Bacteria	2|Bacteria	GK	ROK family	scrK	-	2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_5620079_5	118173.KB235914_gene3833	2.555e-138	449.0	COG0673@1|root,COG0673@2|Bacteria,1G18V@1117|Cyanobacteria,1HG44@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.335,1.1.99.28	ko:K00118,ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_5620079_11	1274374.CBLK010000083_gene3826	8.093e-46	176.0	COG2120@1|root,COG2120@2|Bacteria,1UYGC@1239|Firmicutes,4HJGK@91061|Bacilli,26U25@186822|Paenibacillaceae	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_5620079_3	926569.ANT_08180	1.476e-151	484.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_5620079_8	383372.Rcas_1066	1.036e-94	318.0	COG3394@1|root,COG3394@2|Bacteria,2G6X5@200795|Chloroflexi	200795|Chloroflexi	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GDHHQS3_k127_5620079_9	926569.ANT_11070	7.37e-78	272.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GDHHQS3_k127_5620079_2	926550.CLDAP_10160	2.563e-165	530.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_5620079_15	1116472.MGMO_37c00430	1.592e-16	83.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,1SDT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
GDHHQS3_k127_5620079_1	1183438.GKIL_4202	2.762e-188	602.0	COG4108@1|root,COG4108@2|Bacteria,1G0Y8@1117|Cyanobacteria	1117|Cyanobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
GDHHQS3_k127_5630680_5	926569.ANT_02430	5.735e-44	170.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5630680_2	926569.ANT_14140	3.168e-89	301.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GDHHQS3_k127_5630680_0	526227.Mesil_0601	2.672e-192	612.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
GDHHQS3_k127_5630680_1	926569.ANT_14150	1.735e-101	342.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
GDHHQS3_k127_5630680_7	266117.Rxyl_1792	2.03e-34	139.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GDHHQS3_k127_5630680_4	1120950.KB892709_gene4114	2.599e-58	210.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria,4DWQS@85009|Propionibacteriales	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GDHHQS3_k127_5630680_3	1123368.AUIS01000003_gene1806	1.402e-62	221.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
GDHHQS3_k127_5630680_6	324602.Caur_2791	3.892e-43	162.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,375QT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GDHHQS3_k127_5664180_0	926569.ANT_04650	1.39e-244	761.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
GDHHQS3_k127_5664180_2	357808.RoseRS_3692	9.046e-174	551.0	COG1883@1|root,COG1883@2|Bacteria,2G7ZJ@200795|Chloroflexi,3768I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
GDHHQS3_k127_5664180_3	383372.Rcas_0952	1.849e-24	109.0	COG4770@1|root,COG4770@2|Bacteria,2GBMU@200795|Chloroflexi,3782K@32061|Chloroflexia	32061|Chloroflexia	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GDHHQS3_k127_5664180_1	383372.Rcas_0950	2.003e-202	637.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,376MS@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
GDHHQS3_k127_5667709_7	1499967.BAYZ01000117_gene3320	3.638e-106	349.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GDHHQS3_k127_5667709_3	1499967.BAYZ01000117_gene3321	3.854e-169	537.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisD	-	1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,Histidinol_dh
GDHHQS3_k127_5667709_5	1499967.BAYZ01000117_gene3322	2.416e-135	437.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba2	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
GDHHQS3_k127_5667709_11	1283299.AUKG01000002_gene4309	2.911e-48	185.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
GDHHQS3_k127_5667709_0	1380390.JIAT01000010_gene3535	3.5e-276	871.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GDHHQS3_k127_5667709_13	522306.CAP2UW1_2501	4.145e-19	97.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria	28216|Betaproteobacteria	CT	Domain in cystathionine beta-synthase and other proteins.	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,CBS
GDHHQS3_k127_5667709_10	338963.Pcar_0940	8.649e-52	194.0	COG1349@1|root,COG1349@2|Bacteria,1MXW2@1224|Proteobacteria,42VAF@68525|delta/epsilon subdivisions,2WRBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GDHHQS3_k127_5667709_1	211114.JOEF01000003_gene3012	1.829e-200	651.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GDHHQS3_k127_5667709_9	41431.PCC8801_0885	3.406e-84	292.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.1.1.72,2.7.1.15,2.7.1.4	ko:K00571,ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000,ko02048	-	-	-	PfkB
GDHHQS3_k127_5667709_2	635013.TherJR_0057	1.267e-176	565.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS3_k127_5667709_12	1382304.JNIL01000001_gene2859	3.916e-44	168.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GDHHQS3_k127_5667709_8	498761.HM1_2746	1.064e-92	314.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GDHHQS3_k127_5667709_4	1547437.LL06_05015	4.516e-143	463.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,43J3D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
GDHHQS3_k127_5667709_6	926569.ANT_31320	4.788e-107	354.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS3_k127_5667709_14	316274.Haur_2473	2.376e-15	79.0	COG1177@1|root,COG1177@2|Bacteria,2G80I@200795|Chloroflexi,3776I@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS3_k127_5670078_5	926569.ANT_18580	2.291e-25	113.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GDHHQS3_k127_5670078_4	926569.ANT_18580	3.994e-35	141.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GDHHQS3_k127_5670078_7	324602.Caur_0028	2.988e-18	90.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,375UK@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM iron-sulfur cluster assembly accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
GDHHQS3_k127_5670078_0	1195236.CTER_0541	3.61e-298	934.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GDHHQS3_k127_5670078_3	1173028.ANKO01000018_gene1173	1.408e-117	383.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria,1H74C@1150|Oscillatoriales	1117|Cyanobacteria	JM	Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_5670078_1	926550.CLDAP_10490	5.608e-171	541.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yfnG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_5670078_2	1173022.Cri9333_3402	9.517e-171	545.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria,1HHS8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
GDHHQS3_k127_5670078_6	1173028.ANKO01000018_gene1166	2.326e-23	108.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GDHHQS3_k127_5674749_1	926569.ANT_18150	1.033e-95	322.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GDHHQS3_k127_5674749_0	926569.ANT_18140	1.753e-138	448.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GDHHQS3_k127_5674749_2	1128421.JAGA01000003_gene3248	2.488e-73	265.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
GDHHQS3_k127_5674749_3	247490.KSU1_C0604	9.155e-40	151.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GDHHQS3_k127_5711048_18	880072.Desac_0282	1.508e-20	93.0	COG0591@1|root,COG0745@1|root,COG2199@1|root,COG2203@1|root,COG5002@1|root,COG0591@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1QTSW@1224|Proteobacteria,43CHB@68525|delta/epsilon subdivisions,2X7SG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,SSF,SpoIIE
GDHHQS3_k127_5711048_5	316274.Haur_1218	9.684e-222	699.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
GDHHQS3_k127_5711048_15	316274.Haur_1219	1.808e-39	150.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS3_k127_5711048_12	926550.CLDAP_13320	2.567e-87	302.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GDHHQS3_k127_5711048_3	926550.CLDAP_18280	3.074e-299	927.0	COG0747@1|root,COG0747@2|Bacteria,2G5NA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_5711048_8	926569.ANT_06660	3.503e-168	533.0	COG0601@1|root,COG0601@2|Bacteria,2G64B@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_5711048_6	926569.ANT_06650	1.056e-191	605.0	COG1173@1|root,COG1173@2|Bacteria,2G648@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_5711048_9	926569.ANT_06640	1.601e-166	528.0	COG0444@1|root,COG0444@2|Bacteria,2G5ST@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_5711048_11	1414720.CBYM010000014_gene2773	4.322e-141	451.0	COG4608@1|root,COG4608@2|Bacteria,1V0JP@1239|Firmicutes,24DNW@186801|Clostridia,36QK6@31979|Clostridiaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_5711048_2	926550.CLDAP_05130	0.0	1082.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
GDHHQS3_k127_5711048_1	926569.ANT_24960	0.0	1126.0	COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi	200795|Chloroflexi	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GDHHQS3_k127_5711048_10	926569.ANT_11080	1.421e-163	525.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GDHHQS3_k127_5711048_13	335541.Swol_1899	3.664e-83	291.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
GDHHQS3_k127_5711048_4	1521187.JPIM01000003_gene3021	7.913e-284	897.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
GDHHQS3_k127_5711048_0	1869.MB27_01440	0.0	1202.0	COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales	201174|Actinobacteria	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
GDHHQS3_k127_5711048_14	867845.KI911784_gene2744	1.535e-54	201.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
GDHHQS3_k127_5711048_7	926550.CLDAP_00330	7.706e-182	580.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GDHHQS3_k127_5711048_16	867845.KI911784_gene2559	1.782e-38	151.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GDHHQS3_k127_5711048_19	1122176.KB903565_gene3401	2.729e-05	57.0	COG3591@1|root,COG4935@1|root,COG3591@2|Bacteria,COG4935@2|Bacteria,4NG2K@976|Bacteroidetes,1IY1U@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
GDHHQS3_k127_5711048_17	326442.PSHAa1401	6.667e-31	124.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,2Q13K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GDHHQS3_k127_5730103_14	326427.Cagg_1543	8.36e-33	130.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_5730103_11	926569.ANT_06280	4.884e-49	180.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
GDHHQS3_k127_5730103_0	1267533.KB906737_gene1853	1.835e-180	576.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_5730103_19	40571.JOEA01000002_gene4812	2.293e-11	71.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.243	ko:K16215	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_5730103_20	43989.cce_4213	0.0002091	54.0	COG1807@1|root,COG1807@2|Bacteria,1G3CN@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5730103_8	935845.JADQ01000016_gene3638	7.586e-56	209.0	COG0438@1|root,COG0438@2|Bacteria,1U0P3@1239|Firmicutes,4IA3X@91061|Bacilli,272BY@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
GDHHQS3_k127_5730103_3	1297865.APJD01000016_gene3400	7.878e-130	437.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3JS0Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_5730103_5	269797.Mbar_A2138	8.246e-83	290.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y2AX@28890|Euryarchaeota,2NAPJ@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_5730103_16	1122993.KB898330_gene989	3.208e-30	130.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,2FSMP@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_5730103_1	1487923.DP73_18200	2.489e-139	451.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,263PZ@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GDHHQS3_k127_5730103_6	1121403.AUCV01000031_gene2829	2.767e-77	268.0	COG1091@1|root,COG1091@2|Bacteria,1Q48H@1224|Proteobacteria,42YKE@68525|delta/epsilon subdivisions,2WTPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GDHHQS3_k127_5730103_18	592029.DDD_2290	1.551e-22	111.0	COG0438@1|root,COG0438@2|Bacteria,4NICT@976|Bacteroidetes,1HZ2P@117743|Flavobacteriia,3HKKC@363408|Nonlabens	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
GDHHQS3_k127_5730103_4	1519464.HY22_14300	2.384e-119	406.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_5730103_10	1453500.AT05_02975	1.127e-49	189.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
GDHHQS3_k127_5730103_12	43989.cce_2096	2.355e-47	183.0	COG1215@1|root,COG1215@2|Bacteria,1GPZX@1117|Cyanobacteria,3KIWW@43988|Cyanothece	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_5730103_2	690850.Desaf_3712	5.254e-131	438.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GDHHQS3_k127_5730103_7	521011.Mpal_2194	1.129e-72	256.0	arCOG09486@1|root,arCOG09486@2157|Archaea,2Y3W1@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
GDHHQS3_k127_5730103_15	925409.KI911562_gene150	1.306e-31	136.0	COG2227@1|root,COG2227@2|Bacteria,4NNQC@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_5730103_9	56780.SYN_02659	2.488e-50	191.0	COG0463@1|root,COG0463@2|Bacteria,1NA50@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_5730103_17	56780.SYN_02658	1.481e-24	108.0	COG0463@1|root,COG0463@2|Bacteria,1N0FD@1224|Proteobacteria,42VW1@68525|delta/epsilon subdivisions,2WRUX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_5734580_0	926569.ANT_02790	1.138e-161	527.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
GDHHQS3_k127_5734580_1	926569.ANT_02800	3.133e-119	390.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GDHHQS3_k127_5734580_2	926569.ANT_02540	1.113e-100	337.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GDHHQS3_k127_5734580_4	1122919.KB905551_gene1798	2.741e-18	86.0	COG5552@1|root,COG5552@2|Bacteria,1VCIJ@1239|Firmicutes,4HKXG@91061|Bacilli,26Z0F@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
GDHHQS3_k127_5734580_5	1123508.JH636441_gene3020	4.296e-16	83.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5734580_3	1121015.N789_00635	9.15e-50	182.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,1SGRZ@1236|Gammaproteobacteria,1X6RX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GDHHQS3_k127_5734616_7	525904.Tter_0583	3.531e-31	131.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
GDHHQS3_k127_5734616_13	981383.AEWH01000059_gene2101	2.275e-19	100.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli	91061|Bacilli	P	Phosphonate ABC transporter	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GDHHQS3_k127_5734616_2	926569.ANT_10890	5.944e-86	287.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GDHHQS3_k127_5734616_11	926569.ANT_11370	1.012e-22	104.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
GDHHQS3_k127_5734616_18	591157.SSLG_06053	1.279e-09	62.0	COG3325@1|root,COG3509@1|root,COG4124@1|root,COG3325@2|Bacteria,COG3509@2|Bacteria,COG4124@2|Bacteria,2GJ4D@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_26,RicinB_lectin_2
GDHHQS3_k127_5734616_12	1173028.ANKO01000190_gene449	2.445e-20	95.0	COG1708@1|root,COG1708@2|Bacteria,1G9J2@1117|Cyanobacteria,1HCQI@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GDHHQS3_k127_5734616_10	195253.Syn6312_2069	8.083e-26	112.0	COG1895@1|root,COG1895@2|Bacteria,1G7UH@1117|Cyanobacteria,1H17K@1129|Synechococcus	1117|Cyanobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GDHHQS3_k127_5734616_21	7719.XP_002120296.1	0.000267	45.0	COG0666@1|root,KOG0502@2759|Eukaryota,39TJH@33154|Opisthokonta,3BJ8B@33208|Metazoa,3CYAT@33213|Bilateria,4888U@7711|Chordata	33208|Metazoa	S	KAP family P-loop domain	NKPD1	-	-	ko:K12460,ko:K18167	ko04722,map04722	-	-	-	ko00000,ko00001,ko03029	-	-	-	KAP_NTPase
GDHHQS3_k127_5734616_22	1165096.ARWF01000001_gene1395	0.0007654	48.0	2C4GY@1|root,34053@2|Bacteria,1NYQV@1224|Proteobacteria	1224|Proteobacteria	S	Family of unknown function (DUF5343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5343
GDHHQS3_k127_5734616_23	290397.Adeh_2323	0.0009013	48.0	2F7F0@1|root,33ZVT@2|Bacteria,1NXQR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5734616_0	926569.ANT_10870	2.618e-275	872.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_5734616_1	439235.Dalk_4226	1.86e-254	794.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
GDHHQS3_k127_5734616_15	671143.DAMO_0971	3.989e-14	79.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_5734616_17	158189.SpiBuddy_0610	4.878e-10	64.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GDHHQS3_k127_5734616_9	1089550.ATTH01000001_gene1834	1.099e-28	118.0	COG1669@1|root,COG1669@2|Bacteria,4NXJT@976|Bacteroidetes,1FKC1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_5734616_6	195522.BD01_0081	2.804e-32	129.0	COG2361@1|root,arCOG05024@2157|Archaea,2XYZR@28890|Euryarchaeota	28890|Euryarchaeota	S	to PID 1652090 percent identity	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_5734616_20	1082933.MEA186_10559	1.36e-05	50.0	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2TUXA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_5734616_5	1499967.BAYZ01000120_gene3420	1.315e-42	160.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_5734616_16	760568.Desku_1678	4.558e-12	78.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,STAS
GDHHQS3_k127_5734616_3	290317.Cpha266_0654	4.166e-66	239.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_5734616_4	1283300.ATXB01000002_gene2982	1.971e-59	216.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,1RN7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
GDHHQS3_k127_5734616_8	351348.Maqu_4128	6.548e-30	123.0	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,46A5W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
GDHHQS3_k127_5737686_10	1294265.JCM21738_3766	1.324e-34	140.0	COG1670@1|root,COG1670@2|Bacteria,1V3Q8@1239|Firmicutes,4HH72@91061|Bacilli,1ZQWD@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_5737686_0	1515746.HR45_07865	4.187e-283	887.0	COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria,2Q8XN@267890|Shewanellaceae	1236|Gammaproteobacteria	O	peptidase M6 immune inhibitor A	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
GDHHQS3_k127_5737686_5	926569.ANT_29790	9.827e-78	266.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GDHHQS3_k127_5737686_13	742735.HMPREF9467_00193	2.28e-27	119.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GDHHQS3_k127_5737686_16	1121920.AUAU01000018_gene1775	2.086e-05	53.0	COG2318@1|root,COG2318@2|Bacteria,3Y4HW@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_5737686_3	926569.ANT_14300	2.956e-110	359.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_5737686_8	1163408.UU9_06669	2.642e-38	150.0	COG1670@1|root,COG1670@2|Bacteria,1N36Q@1224|Proteobacteria,1S9V1@1236|Gammaproteobacteria,1X6ZV@135614|Xanthomonadales	135614|Xanthomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_5737686_2	926569.ANT_14310	1.746e-112	369.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GDHHQS3_k127_5737686_7	926569.ANT_14320	1.599e-38	149.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
GDHHQS3_k127_5737686_12	926569.ANT_14330	3.028e-32	130.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GDHHQS3_k127_5737686_1	926569.ANT_14340	2.005e-199	643.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
GDHHQS3_k127_5737686_9	926569.ANT_14350	6.251e-38	149.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi	200795|Chloroflexi	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GDHHQS3_k127_5737686_6	926569.ANT_11280	3.777e-54	195.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GDHHQS3_k127_5737686_4	926569.ANT_11270	2.036e-88	299.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
GDHHQS3_k127_5737686_14	1120934.KB894404_gene864	5.436e-08	66.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,Germane,PG_binding_1
GDHHQS3_k127_5740654_8	880073.Calab_0815	4.588e-90	317.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GDHHQS3_k127_5740654_9	926569.ANT_13820	7.879e-80	271.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GDHHQS3_k127_5740654_3	926569.ANT_30250	4.385e-131	430.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_5740654_5	1382356.JQMP01000003_gene1994	6.396e-104	347.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GDHHQS3_k127_5740654_11	926569.ANT_13800	3.962e-47	175.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
GDHHQS3_k127_5740654_1	926569.ANT_13790	1.236e-246	767.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GDHHQS3_k127_5740654_7	926569.ANT_13780	2.691e-98	330.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GDHHQS3_k127_5740654_0	926569.ANT_13770	2.196e-261	814.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GDHHQS3_k127_5740654_2	926569.ANT_06070	4.195e-152	489.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_5740654_6	765420.OSCT_3000	1.46e-98	338.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
GDHHQS3_k127_5740654_12	765420.OSCT_2999	1.799e-46	173.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
GDHHQS3_k127_5740654_4	765420.OSCT_2998	1.084e-114	383.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pyr_redox_2
GDHHQS3_k127_5740654_17	368407.Memar_0359	2.557e-08	59.0	COG1143@1|root,arCOG01543@2157|Archaea	2157|Archaea	C	Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I)	echF	-	-	ko:K14091,ko:K15831	-	-	-	-	ko00000	-	-	iAF692.Mbar_A0147	Fer4,Fer4_7
GDHHQS3_k127_5740654_15	926569.ANT_08190	1.148e-22	98.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GDHHQS3_k127_5740654_13	1009370.ALO_05268	1.812e-43	166.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GDHHQS3_k127_5740654_18	926569.ANT_19170	1.075e-06	61.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
GDHHQS3_k127_5740654_14	1190606.AJYG01000193_gene2547	6.194e-23	101.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,1RQJH@1236|Gammaproteobacteria,1XSEM@135623|Vibrionales	135623|Vibrionales	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
GDHHQS3_k127_5740654_10	926569.ANT_22550	1.829e-68	239.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
GDHHQS3_k127_5740654_16	616991.JPOO01000001_gene4601	1.456e-18	91.0	COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia	976|Bacteroidetes	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GDHHQS3_k127_5748616_2	926569.ANT_08150	3.029e-128	419.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_5748616_1	926569.ANT_08160	3.392e-130	428.0	COG0842@1|root,COG0842@2|Bacteria,2G774@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_5748616_3	926569.ANT_08170	1.135e-121	403.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_5748616_4	1382306.JNIM01000001_gene1210	2.172e-39	157.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
GDHHQS3_k127_5748616_0	1173026.Glo7428_0555	4.071e-161	530.0	COG2203@1|root,COG3322@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3322@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_4
GDHHQS3_k127_5757537_1	926569.ANT_26230	3.888e-117	389.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GDHHQS3_k127_5757537_3	1123059.KB823013_gene650	5.482e-13	72.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,43YKN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GDHHQS3_k127_5757537_2	926569.ANT_26250	1.471e-48	177.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
GDHHQS3_k127_5757537_0	926569.ANT_25910	6.088e-119	396.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GDHHQS3_k127_5766716_1	926569.ANT_18060	1.19e-197	634.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GDHHQS3_k127_5766716_9	1499967.BAYZ01000170_gene5494	1.967e-42	158.0	COG2154@1|root,COG2154@2|Bacteria	2|Bacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GDHHQS3_k127_5766716_4	1122223.KB890687_gene2749	1.448e-141	466.0	COG3345@1|root,COG3345@2|Bacteria,1WIV5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
GDHHQS3_k127_5766716_11	573063.Metin_1144	4.993e-16	85.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX3W@28890|Euryarchaeota,23QY6@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GDHHQS3_k127_5766716_3	476272.RUMHYD_02346	7.904e-151	489.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_5766716_2	1121378.KB899751_gene3516	9.723e-162	521.0	COG0161@1|root,COG0161@2|Bacteria,1WISD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
GDHHQS3_k127_5766716_0	211165.AJLN01000116_gene3197	1.705e-217	684.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GDHHQS3_k127_5766716_8	251221.35211923	2.599e-91	312.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS3_k127_5766716_12	1121422.AUMW01000012_gene2924	2.09e-07	54.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,2608J@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_5766716_6	309801.trd_0523	6.555e-119	392.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_5766716_5	926550.CLDAP_37540	2.616e-120	393.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS3_k127_5766716_7	926550.CLDAP_37550	2.585e-105	349.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi	200795|Chloroflexi	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS3_k127_5766716_10	926550.CLDAP_37560	4.063e-29	119.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GDHHQS3_k127_5846592_7	926569.ANT_19390	2.306e-81	276.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GDHHQS3_k127_5846592_6	926569.ANT_19400	4.869e-83	282.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GDHHQS3_k127_5846592_4	926569.ANT_19410	3.996e-101	335.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GDHHQS3_k127_5846592_5	926569.ANT_19420	5.086e-86	308.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GDHHQS3_k127_5846592_14	926569.ANT_19430	1.407e-27	118.0	2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi	200795|Chloroflexi	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS3_k127_5846592_13	926550.CLDAP_40040	5.986e-34	138.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
GDHHQS3_k127_5846592_11	926569.ANT_19460	2.078e-35	141.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GDHHQS3_k127_5846592_0	926569.ANT_19480	1.915e-285	893.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GDHHQS3_k127_5846592_10	926569.ANT_19490	1.165e-58	207.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GDHHQS3_k127_5846592_8	243164.DET0571	4.758e-67	245.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS3_k127_5846592_3	243164.DET0573	1.854e-120	406.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GDHHQS3_k127_5846592_12	926569.ANT_25240	7.571e-35	145.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GDHHQS3_k127_5846592_2	1169143.KB911043_gene3668	1.331e-135	438.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VMYU@28216|Betaproteobacteria,1K2AM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
GDHHQS3_k127_5846592_9	926569.ANT_02910	6.668e-60	214.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
GDHHQS3_k127_5894867_2	926569.ANT_20860	1.08e-70	243.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GDHHQS3_k127_5894867_1	926569.ANT_20880	3.318e-90	311.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_5894867_0	997346.HMPREF9374_0894	5.471e-153	493.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GDHHQS3_k127_5894867_4	1128421.JAGA01000002_gene1728	6.179e-05	45.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GDHHQS3_k127_5928706_7	1121448.DGI_1207	8.835e-05	48.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,42UR2@68525|delta/epsilon subdivisions,2WQER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GDHHQS3_k127_5928706_4	1173024.KI912152_gene425	8.311e-24	109.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GDHHQS3_k127_5928706_3	304371.MCP_0795	1.11e-68	238.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GDHHQS3_k127_5928706_2	937777.Deipe_2186	7.709e-70	244.0	COG4424@1|root,COG4424@2|Bacteria,1WN1P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Sulfotransferase family	-	-	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
GDHHQS3_k127_5928706_1	485913.Krac_10180	8.924e-74	258.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS3_k127_5928706_6	322710.Avin_39260	4.342e-05	47.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,1RSAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
GDHHQS3_k127_5928706_5	255470.cbdbA1239	6.607e-16	81.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_5928706_0	861299.J421_4065	1.376e-126	416.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
GDHHQS3_k127_5936515_1	326427.Cagg_1550	9.382e-174	552.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
GDHHQS3_k127_5936515_4	926569.ANT_06510	1.557e-102	353.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	PMT_2
GDHHQS3_k127_5936515_3	926569.ANT_06420	2.945e-121	398.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_5936515_8	1124983.PFLCHA0_c21940	5.484e-46	181.0	2E0I2@1|root,33KZA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5936515_13	266117.Rxyl_3104	2.63e-32	139.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS3_k127_5936515_12	398512.JQKC01000037_gene4525	7.578e-33	132.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,3WQ51@541000|Ruminococcaceae	186801|Clostridia	S	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_5936515_17	1210908.HSB1_22680	3.333e-06	58.0	COG5427@1|root,arCOG00563@2157|Archaea,2XU14@28890|Euryarchaeota,23TFA@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5936515_15	290402.Cbei_3139	3.932e-10	62.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,36KXB@31979|Clostridiaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_5936515_9	926569.ANT_26080	3.325e-39	165.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5936515_0	926569.ANT_06410	5.637e-181	580.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
GDHHQS3_k127_5936515_2	926569.ANT_06400	6.979e-133	430.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
GDHHQS3_k127_5936515_6	926569.ANT_06390	1.354e-97	327.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
GDHHQS3_k127_5936515_7	926569.ANT_06380	3.497e-72	252.0	COG1861@1|root,COG1861@2|Bacteria,2G8I7@200795|Chloroflexi	200795|Chloroflexi	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
GDHHQS3_k127_5936515_10	344747.PM8797T_23856	7.699e-39	164.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5936515_16	518766.Rmar_1869	5.474e-08	59.0	COG5416@1|root,COG5416@2|Bacteria,4PEVU@976|Bacteroidetes,1FJPM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
GDHHQS3_k127_5936515_5	436308.Nmar_0137	7.057e-100	341.0	COG2234@1|root,arCOG02959@2157|Archaea	2157|Archaea	S	Peptidase M28	ywaD2	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GDHHQS3_k127_5936515_11	617140.AJZE01000062_gene2964	6.458e-35	143.0	COG2746@1|root,COG2746@2|Bacteria,1MZ5F@1224|Proteobacteria,1TK0N@1236|Gammaproteobacteria,1Y1XG@135623|Vibrionales	135623|Vibrionales	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
GDHHQS3_k127_5936515_14	926569.ANT_06370	1.375e-16	81.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_5939870_5	1270196.JCKI01000008_gene1479	9.825e-26	111.0	2AVBG@1|root,31M2S@2|Bacteria,4NQIJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5939870_3	485913.Krac_11884	1.36e-115	386.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GDHHQS3_k127_5939870_0	383372.Rcas_2231	9.383e-205	640.0	COG2189@1|root,COG2189@2|Bacteria,2GAC9@200795|Chloroflexi,376M5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GDHHQS3_k127_5939870_4	526224.Bmur_1368	1.35e-32	132.0	2BF59@1|root,328XJ@2|Bacteria,2JB5N@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5939870_2	926569.ANT_23460	4.866e-164	526.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GDHHQS3_k127_5939870_1	926569.ANT_23450	6.545e-176	559.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GDHHQS3_k127_5939870_7	1410634.JHVD01000001_gene1509	0.0007293	49.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4DRPK@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GDHHQS3_k127_5945434_2	926550.CLDAP_10960	4.249e-43	162.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GDHHQS3_k127_5945434_0	926569.ANT_30500	0.0	1082.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GDHHQS3_k127_5946481_9	1449126.JQKL01000101_gene2567	2.609e-05	49.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,24AQA@186801|Clostridia	186801|Clostridia	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
GDHHQS3_k127_5946481_2	118168.MC7420_3145	6.911e-122	407.0	COG3385@1|root,COG3385@2|Bacteria,1G3D9@1117|Cyanobacteria,1H9WI@1150|Oscillatoriales	1117|Cyanobacteria	L	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,Tnp_DNA_bind
GDHHQS3_k127_5946481_8	32057.KB217478_gene2471	1.296e-21	98.0	COG4634@1|root,COG4634@2|Bacteria,1GHZS@1117|Cyanobacteria,1HSRB@1161|Nostocales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GDHHQS3_k127_5946481_7	1173023.KE650771_gene723	1.07e-25	108.0	COG2442@1|root,COG2442@2|Bacteria,1G9UJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_5946481_1	316274.Haur_4945	9.769e-141	464.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GDHHQS3_k127_5946481_6	926569.ANT_19780	4.034e-52	194.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
GDHHQS3_k127_5946481_5	1192034.CAP_8495	3.971e-57	209.0	COG4632@1|root,COG4632@2|Bacteria,1PIAX@1224|Proteobacteria,43DRZ@68525|delta/epsilon subdivisions,2WYR4@28221|Deltaproteobacteria,2Z0EH@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GDHHQS3_k127_5946481_3	926569.ANT_14370	6.186e-109	359.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
GDHHQS3_k127_5946481_0	926569.ANT_14380	9.914e-161	518.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_5946481_4	926569.ANT_11300	7.762e-68	237.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_594829_3	760568.Desku_0060	2.759e-62	226.0	COG0407@1|root,COG0407@2|Bacteria,1UYXW@1239|Firmicutes,25DH8@186801|Clostridia,264CR@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246	ko:K14080	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R09098,R10000	RC00035,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
GDHHQS3_k127_594829_0	765420.OSCT_1692	4.805e-255	827.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi	200795|Chloroflexi	CO	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
GDHHQS3_k127_594829_2	880073.Calab_0286	4.654e-65	228.0	COG1294@1|root,COG1294@2|Bacteria,2NS31@2323|unclassified Bacteria	2|Bacteria	C	PFAM Cytochrome bd ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120	Cyt_bd_oxida_II
GDHHQS3_k127_5972416_8	392500.Swoo_4628	2.595e-30	125.0	COG2894@1|root,COG2894@2|Bacteria	2|Bacteria	D	cell division	minD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
GDHHQS3_k127_5972416_10	521096.Tpau_3216	0.0001883	52.0	2EZCI@1|root,33SHV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5972416_5	926569.ANT_24750	3.404e-44	167.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_5972416_7	926569.ANT_24760	1.879e-36	146.0	2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GDHHQS3_k127_5972416_1	926569.ANT_24770	5.747e-204	644.0	COG5557@1|root,COG5557@2|Bacteria,2G68D@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GDHHQS3_k127_5972416_2	926569.ANT_24780	4.913e-104	343.0	COG0437@1|root,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
GDHHQS3_k127_5972416_0	926569.ANT_24790	2.075e-222	712.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi	200795|Chloroflexi	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
GDHHQS3_k127_5972416_4	926569.ANT_24800	2.807e-57	205.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GDHHQS3_k127_5972416_6	357808.RoseRS_0799	5.953e-42	161.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi,377PI@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GDHHQS3_k127_5972416_3	1128421.JAGA01000002_gene1676	5.356e-79	274.0	COG0265@1|root,COG0265@2|Bacteria,2NQV1@2323|unclassified Bacteria	2|Bacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GDHHQS3_k127_5972416_9	1122222.AXWR01000002_gene2178	7.109e-08	57.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_5977145_17	203119.Cthe_2397	3.165e-06	57.0	COG1807@1|root,COG1807@2|Bacteria,1V0V2@1239|Firmicutes,24BJF@186801|Clostridia,3WN2P@541000|Ruminococcaceae	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5977145_11	926569.ANT_22220	8.589e-55	199.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
GDHHQS3_k127_5977145_6	926550.CLDAP_19350	7.766e-112	367.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	iEC55989_1330.EC55989_1575,iECIAI1_1343.ECIAI1_1439,iECO111_1330.ECO111_1832,iECO26_1355.ECO26_2042,iECW_1372.ECW_m1571,iECs_1301.ECs2047,iEKO11_1354.EKO11_2376,iUMNK88_1353.UMNK88_1846,iWFL_1372.ECW_m1571,iZ_1308.Z2276,ic_1306.c1867	BPD_transp_1
GDHHQS3_k127_5977145_5	395961.Cyan7425_3620	1.854e-117	385.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,3KIME@43988|Cyanothece	1117|Cyanobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
GDHHQS3_k127_5977145_3	395961.Cyan7425_3621	2.473e-137	445.0	COG3842@1|root,COG3842@2|Bacteria,1G1HQ@1117|Cyanobacteria,3KGWZ@43988|Cyanothece	1117|Cyanobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_5977145_2	321332.CYB_1464	3.041e-171	546.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_8
GDHHQS3_k127_5977145_4	1128421.JAGA01000002_gene177	3.601e-133	434.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_5977145_8	926550.CLDAP_21600	1.057e-97	329.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_5977145_9	926569.ANT_00730	1.97e-73	273.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_5977145_0	485913.Krac_12092	6.339e-244	762.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GDHHQS3_k127_5977145_1	794903.OPIT5_14440	7.072e-176	565.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GDHHQS3_k127_5977145_14	382464.ABSI01000010_gene3730	3.919e-27	116.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GDHHQS3_k127_5977145_12	926569.ANT_07800	8.66e-43	163.0	COG1437@1|root,COG1437@2|Bacteria,2G9FW@200795|Chloroflexi	200795|Chloroflexi	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GDHHQS3_k127_5977145_15	882083.SacmaDRAFT_2555	1.752e-16	85.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4E4KM@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_5977145_7	926569.ANT_04560	2.756e-102	339.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
GDHHQS3_k127_5977145_10	926569.ANT_04550	8.565e-72	250.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GDHHQS3_k127_5977145_16	926569.ANT_04540	1.762e-09	58.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GDHHQS3_k127_5989614_8	926569.ANT_15740	3.777e-28	120.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
GDHHQS3_k127_5989614_7	247490.KSU1_D0148	1.1e-35	149.0	COG1723@1|root,COG1723@2|Bacteria,2J0AJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5989614_6	1120999.JONM01000011_gene1670	1.547e-36	144.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
GDHHQS3_k127_5989614_4	926569.ANT_19230	2.335e-50	186.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GDHHQS3_k127_5989614_2	485913.Krac_12461	1.541e-81	284.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GDHHQS3_k127_5989614_1	479434.Sthe_0495	7.639e-97	330.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,27XFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GDHHQS3_k127_5989614_0	926569.ANT_05380	2.369e-171	545.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
GDHHQS3_k127_5989614_3	926569.ANT_05390	1.054e-55	200.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS3_k127_5993770_6	1307759.JOMJ01000004_gene2965	2.039e-10	64.0	COG0500@1|root,COG2226@2|Bacteria,1RKQD@1224|Proteobacteria,42V0D@68525|delta/epsilon subdivisions,2WRXU@28221|Deltaproteobacteria,2MCXC@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GDHHQS3_k127_5993770_3	1237149.C900_00291	8.179e-48	175.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_5993770_4	1237149.C900_00291	5.864e-41	154.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_5993770_0	880073.Calab_3175	2.347e-129	422.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_5993770_2	926569.ANT_19840	1.288e-102	340.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
GDHHQS3_k127_5993770_1	485916.Dtox_1611	4.84e-111	365.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GDHHQS3_k127_5993770_5	547163.BN979_04981	5.855e-17	86.0	2AYN4@1|root,31QSM@2|Bacteria,2HSX3@201174|Actinobacteria,23EDJ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_5997472_4	926550.CLDAP_36710	2.05e-25	107.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GDHHQS3_k127_5997472_1	1385517.N800_00720	4.691e-32	143.0	COG1361@1|root,COG3188@1|root,COG1361@2|Bacteria,COG3188@2|Bacteria,1R5G4@1224|Proteobacteria,1T61M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GDHHQS3_k127_5997472_8	754027.HMPREF9554_02232	2.368e-05	54.0	COG0671@1|root,COG0671@2|Bacteria,2J7YV@203691|Spirochaetes	203691|Spirochaetes	I	Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS3_k127_5997472_3	1499967.BAYZ01000131_gene330	2.159e-29	120.0	2BY23@1|root,345FG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5997472_2	195253.Syn6312_1019	3.547e-31	125.0	COG3514@1|root,COG3514@2|Bacteria,1GJK1@1117|Cyanobacteria,1H3JX@1129|Synechococcus	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5997472_0	671143.DAMO_3092	1.638e-41	155.0	COG5499@1|root,COG5499@2|Bacteria,2NRMJ@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
GDHHQS3_k127_5997472_6	768710.DesyoDRAFT_4742	3.096e-14	73.0	2DNMU@1|root,32Y5V@2|Bacteria,1VN9X@1239|Firmicutes,24TPS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_5997472_5	195522.BD01_0197	1.419e-22	102.0	COG1848@1|root,arCOG02222@2157|Archaea,2Y1YE@28890|Euryarchaeota,24558@183968|Thermococci	183968|Thermococci	V	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_5997472_7	245174.XP_009267232.1	4.945e-10	61.0	COG0120@1|root,COG0449@1|root,KOG1268@2759|Eukaryota,KOG3075@2759|Eukaryota,38DW1@33154|Opisthokonta,3NUR2@4751|Fungi,3UYU2@5204|Basidiomycota	4751|Fungi	M	L-glutamine D-fructose 6-phosphate amidotansferase	GFA1	GO:0000271,GO:0003674,GO:0003824,GO:0004360,GO:0005975,GO:0005976,GO:0006002,GO:0006022,GO:0006023,GO:0006030,GO:0006031,GO:0006037,GO:0006038,GO:0006040,GO:0006041,GO:0006042,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009272,GO:0009987,GO:0010383,GO:0016043,GO:0016051,GO:0016740,GO:0016769,GO:0017144,GO:0019538,GO:0019637,GO:0030447,GO:0030448,GO:0033692,GO:0034221,GO:0034637,GO:0034641,GO:0034645,GO:0035690,GO:0036211,GO:0040007,GO:0042221,GO:0042493,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044281,GO:0045229,GO:0046349,GO:0046483,GO:0050896,GO:0051278,GO:0051716,GO:0055086,GO:0070085,GO:0070548,GO:0070589,GO:0070592,GO:0070887,GO:0071554,GO:0071704,GO:0071840,GO:0071852,GO:0071966,GO:1901071,GO:1901073,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iMM904.YKL104C,iND750.YKL104C	GATase_6,SIS
GDHHQS3_k127_6004063_6	357808.RoseRS_3404	5.847e-10	61.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia	32061|Chloroflexia	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS3_k127_6004063_2	926569.ANT_11710	4.683e-93	314.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_6004063_3	926569.ANT_11700	8.845e-54	195.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GDHHQS3_k127_6004063_1	926569.ANT_11680	2.062e-153	501.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
GDHHQS3_k127_6004063_0	926569.ANT_11670	4.661e-154	491.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_6004063_4	926569.ANT_11660	1.516e-43	164.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
GDHHQS3_k127_6004063_5	926550.CLDAP_33660	2.822e-14	74.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_6023932_13	926569.ANT_03590	7.273e-11	68.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GDHHQS3_k127_6023932_1	926569.ANT_19720	1.013e-75	271.0	COG1594@1|root,COG1594@2|Bacteria	2|Bacteria	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GDHHQS3_k127_6023932_0	574087.Acear_1783	2.368e-90	307.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WBAE@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
GDHHQS3_k127_6023932_11	867845.KI911784_gene1274	2.03e-27	128.0	COG0457@1|root,COG0457@2|Bacteria	867845.KI911784_gene1274|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6023932_15	1499967.BAYZ01000076_gene842	1.941e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
GDHHQS3_k127_6023932_14	290317.Cpha266_0297	1.99e-10	74.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1FF9A@1090|Chlorobi	1090|Chlorobi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,MarR,TPR_10,TPR_8
GDHHQS3_k127_6023932_12	1346330.M472_22195	4.425e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GDHHQS3_k127_6023932_8	5911.EAR82403	2.812e-38	166.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
GDHHQS3_k127_6023932_7	221288.JH992901_gene644	3.136e-39	162.0	COG4928@1|root,COG4928@2|Bacteria,1G0KU@1117|Cyanobacteria	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
GDHHQS3_k127_6023932_4	926550.CLDAP_08440	2.921e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_6023932_10	926569.ANT_23300	1.624e-29	122.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GDHHQS3_k127_6023932_6	926550.CLDAP_08440	2.542e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_6023932_9	526227.Mesil_2849	5.866e-37	160.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1WM3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_8
GDHHQS3_k127_6023932_16	402777.KB235904_gene3412	3.874e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_6023932_2	861299.J421_2299	4.157e-68	241.0	COG4127@1|root,COG4127@2|Bacteria,1ZV3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
GDHHQS3_k127_6023932_3	926569.ANT_17350	4.122e-62	226.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GDHHQS3_k127_6023932_5	997296.PB1_11914	5.609e-60	218.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,1ZCQS@1386|Bacillus	91061|Bacilli	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_6042844_0	926569.ANT_03530	0.0	1095.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GDHHQS3_k127_6042844_20	926569.ANT_18900	3.51e-54	203.0	COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi	200795|Chloroflexi	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
GDHHQS3_k127_6042844_16	926569.ANT_09370	7.228e-66	239.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GDHHQS3_k127_6042844_2	926569.ANT_09360	2.429e-213	670.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GDHHQS3_k127_6042844_9	926569.ANT_04320	5.808e-120	390.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_6042844_8	926569.ANT_22760	4.035e-136	445.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	MFS_1
GDHHQS3_k127_6042844_32	96561.Dole_2706	3.417e-13	77.0	2CSAJ@1|root,2ZZZN@2|Bacteria,1NI4I@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_29	357808.RoseRS_0526	5.512e-28	117.0	2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi	200795|Chloroflexi	S	pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_6042844_27	649638.Trad_1431	7.68e-35	134.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HigB-like_toxin
GDHHQS3_k127_6042844_25	649638.Trad_1432	7.099e-41	156.0	COG3093@1|root,COG3093@2|Bacteria,1WKRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG3093 Plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS3_k127_6042844_5	163908.KB235896_gene4878	7.732e-154	498.0	COG3385@1|root,COG3385@2|Bacteria,1G2T1@1117|Cyanobacteria,1HMX0@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
GDHHQS3_k127_6042844_33	1123075.AUDP01000004_gene786	3.465e-13	80.0	COG1555@1|root,COG1555@2|Bacteria,1UR4G@1239|Firmicutes,258YC@186801|Clostridia,3WP1G@541000|Ruminococcaceae	186801|Clostridia	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_4	517418.Ctha_2426	2.871e-176	563.0	COG0366@1|root,COG0366@2|Bacteria,1FFH6@1090|Chlorobi	1090|Chlorobi	C	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
GDHHQS3_k127_6042844_23	1449355.JQNR01000005_gene5856	9.483e-42	161.0	COG2606@1|root,COG2606@2|Bacteria,2IMZE@201174|Actinobacteria	201174|Actinobacteria	G	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GDHHQS3_k127_6042844_12	1121015.N789_06760	1.434e-97	325.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1XAYP@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GDHHQS3_k127_6042844_28	765952.PUV_26370	1.886e-30	123.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_7	1122947.FR7_1419	4.227e-138	451.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4H3UJ@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_6042844_26	1173027.Mic7113_0232	7.007e-40	158.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HAKG@1150|Oscillatoriales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_10	204669.Acid345_1702	3.016e-116	383.0	COG1087@1|root,COG1087@2|Bacteria,3Y3FK@57723|Acidobacteria,2JI2G@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GDHHQS3_k127_6042844_21	926569.ANT_28940	1.267e-46	181.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GDHHQS3_k127_6042844_44	491205.JARQ01000006_gene2863	0.0002817	44.0	2AC8U@1|root,311TH@2|Bacteria,4PGNY@976|Bacteroidetes,1IHFY@117743|Flavobacteriia,3ZU66@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_43	1220534.B655_2290	0.0001299	53.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y5UU@28890|Euryarchaeota,23PUE@183925|Methanobacteria	183925|Methanobacteria	L	NERD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GDHHQS3_k127_6042844_13	926569.ANT_00990	6.399e-91	304.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_6042844_18	515635.Dtur_1531	7.19e-57	205.0	COG0164@1|root,COG0164@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GDHHQS3_k127_6042844_17	926569.ANT_28020	9.767e-60	216.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
GDHHQS3_k127_6042844_3	926569.ANT_00270	6.595e-207	652.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GDHHQS3_k127_6042844_41	1121033.AUCF01000008_gene5602	2.192e-05	53.0	COG0288@1|root,COG0288@2|Bacteria,1RH7R@1224|Proteobacteria,2UAGZ@28211|Alphaproteobacteria,2JXM6@204441|Rhodospirillales	204441|Rhodospirillales	P	carbonate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6042844_15	944479.JQLX01000013_gene1442	2.414e-76	276.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
GDHHQS3_k127_6042844_19	247490.KSU1_C1143	1.806e-55	198.0	COG1943@1|root,COG1943@2|Bacteria,2J0GJ@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GDHHQS3_k127_6042844_30	262316.MAP_0519c	3.345e-24	106.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,239MD@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_6042844_35	1089550.ATTH01000001_gene947	4.748e-12	73.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
GDHHQS3_k127_6042844_34	1173027.Mic7113_5194	3.999e-13	71.0	COG2361@1|root,COG2361@2|Bacteria,1G80M@1117|Cyanobacteria,1HCPE@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_6042844_39	871963.Desdi_0698	4.367e-06	48.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,2635X@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_6042844_1	926569.ANT_28950	2.855e-257	803.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
GDHHQS3_k127_6042844_22	926569.ANT_30860	5.28e-46	176.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_6042844_24	926569.ANT_30860	9.483e-42	161.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_6042844_6	926569.ANT_17310	1.036e-152	491.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_6042844_11	383372.Rcas_0299	1.267e-107	361.0	COG1168@1|root,COG1168@2|Bacteria,2G614@200795|Chloroflexi,375GA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase, class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_6042844_14	479434.Sthe_2389	6.689e-89	297.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GDHHQS3_k127_6042844_31	1535422.ND16A_2433	9.264e-20	93.0	COG3427@1|root,COG3427@2|Bacteria,1NAN4@1224|Proteobacteria,1SRDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_6062989_10	927677.ALVU02000001_gene1906	1.593e-23	104.0	2C4F2@1|root,331RG@2|Bacteria,1G9S1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6062989_9	1229172.JQFA01000002_gene2339	1.802e-31	126.0	2C7RX@1|root,32RJP@2|Bacteria,1G859@1117|Cyanobacteria,1HC7Z@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6062989_4	926569.ANT_20510	2.538e-133	434.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
GDHHQS3_k127_6062989_11	1408254.T458_16740	6.665e-23	100.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,26YZG@186822|Paenibacillaceae	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GDHHQS3_k127_6062989_2	926569.ANT_20570	4.634e-148	473.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GDHHQS3_k127_6062989_1	926569.ANT_20580	1.625e-178	565.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GDHHQS3_k127_6062989_0	926569.ANT_12980	0.0	1031.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
GDHHQS3_k127_6062989_3	926569.ANT_16630	5.519e-136	442.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
GDHHQS3_k127_6062989_8	926569.ANT_16620	1.789e-66	237.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
GDHHQS3_k127_6062989_6	309801.trd_A0702	8.101e-87	296.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
GDHHQS3_k127_6062989_5	926569.ANT_16610	3.561e-95	318.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GDHHQS3_k127_6062989_7	926569.ANT_16600	3.643e-76	273.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GDHHQS3_k127_6082718_3	742733.HMPREF9469_00494	3.759e-14	74.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,220M1@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
GDHHQS3_k127_6082718_1	1051632.TPY_0830	4.368e-48	188.0	COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,24803@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_6082718_0	886293.Sinac_6174	4.048e-89	304.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS3_k127_6082718_2	926569.ANT_18940	3.634e-21	97.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi	200795|Chloroflexi	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_6087003_27	926569.ANT_30470	4.849e-05	48.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
GDHHQS3_k127_6087003_17	926569.ANT_30480	8.27e-58	209.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GDHHQS3_k127_6087003_9	864702.OsccyDRAFT_4839	6.421e-87	297.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1HEPB@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_6087003_20	926569.ANT_03600	1.671e-44	168.0	COG1225@1|root,COG1225@2|Bacteria,2G9KJ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_6087003_10	926569.ANT_30100	3.46e-84	301.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
GDHHQS3_k127_6087003_14	926569.ANT_31550	1.297e-71	246.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GDHHQS3_k127_6087003_24	1540257.JQMW01000013_gene1277	9.752e-35	137.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,36IKR@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_6087003_2	926569.ANT_31560	2.164e-145	471.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GDHHQS3_k127_6087003_12	629265.PMA4326_10155	1.954e-81	280.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1Z78Y@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GDHHQS3_k127_6087003_13	1521187.JPIM01000026_gene1158	4.965e-79	274.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,3766P@32061|Chloroflexia	32061|Chloroflexia	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS3_k127_6087003_4	324602.Caur_0484	1.011e-96	325.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,3766P@32061|Chloroflexia	32061|Chloroflexia	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GDHHQS3_k127_6087003_18	526222.Desal_3522	3.999e-56	205.0	COG3275@1|root,COG3275@2|Bacteria,1PY1H@1224|Proteobacteria,43EPZ@68525|delta/epsilon subdivisions,2X1BK@28221|Deltaproteobacteria,2MFQ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	-
GDHHQS3_k127_6087003_21	525904.Tter_2111	2.486e-42	165.0	COG0619@1|root,COG0619@2|Bacteria,2NR9U@2323|unclassified Bacteria	2|Bacteria	P	Cobalt transport protein	-	-	-	ko:K02008,ko:K16785	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS3_k127_6087003_5	1128421.JAGA01000001_gene2131	1.129e-93	316.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS3_k127_6087003_11	312284.A20C1_06196	2.85e-82	282.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,3UXBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
GDHHQS3_k127_6087003_23	1089547.KB913013_gene4388	4.661e-38	146.0	COG1661@1|root,COG1661@2|Bacteria,4NPS1@976|Bacteroidetes,47PS2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
GDHHQS3_k127_6087003_22	926569.ANT_03650	9.038e-40	154.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GDHHQS3_k127_6087003_16	926569.ANT_03640	5.067e-58	213.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS3_k127_6087003_3	926569.ANT_03630	2.716e-106	353.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
GDHHQS3_k127_6087003_7	383372.Rcas_2663	9.543e-90	327.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS3_k127_6087003_25	1121428.DESHY_110386___1	6.478e-32	145.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
GDHHQS3_k127_6087003_0	326427.Cagg_2500	4.583e-200	636.0	COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate lyase	-	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GDHHQS3_k127_6087003_6	926569.ANT_19370	2.658e-93	317.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GDHHQS3_k127_6087003_8	383372.Rcas_3156	1.904e-89	305.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6087003_26	742818.HMPREF9451_00664	1.635e-17	92.0	COG0500@1|root,COG0500@2|Bacteria,2I6HE@201174|Actinobacteria,4CW1I@84998|Coriobacteriia	84998|Coriobacteriia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GDHHQS3_k127_6087003_19	1158338.JNLJ01000001_gene956	2.252e-55	202.0	COG0175@1|root,COG0175@2|Bacteria,2G4VI@200783|Aquificae	200783|Aquificae	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
GDHHQS3_k127_6087003_1	926569.ANT_05360	1.029e-171	547.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GDHHQS3_k127_6155879_2	926550.CLDAP_09870	1.591e-150	486.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
GDHHQS3_k127_6155879_1	665571.STHERM_c12790	7.636e-151	491.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GDHHQS3_k127_6155879_3	926550.CLDAP_06960	5.991e-140	458.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_6155879_0	926550.CLDAP_06970	2e-204	653.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
GDHHQS3_k127_6155879_5	1173026.Glo7428_4597	7.536e-103	346.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria	1117|Cyanobacteria	P	Sodium calcium exchanger	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GDHHQS3_k127_6155879_9	203124.Tery_2240	2.608e-14	79.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1HB2G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
GDHHQS3_k127_6155879_4	765910.MARPU_00280	3.329e-108	366.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
GDHHQS3_k127_6155879_7	926569.ANT_04420	8.758e-30	121.0	COG3870@1|root,COG3870@2|Bacteria	2|Bacteria	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GDHHQS3_k127_6155879_8	309801.trd_0731	3.436e-15	78.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YH0@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GDHHQS3_k127_6155879_6	316274.Haur_3232	2.774e-32	141.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Trans_reg_C
GDHHQS3_k127_6167286_0	926569.ANT_11950	1.921e-231	726.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GDHHQS3_k127_6203069_6	1150474.JQJI01000004_gene426	2.051e-12	69.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_6203069_7	643648.Slip_1839	3.237e-11	66.0	COG1724@1|root,COG1724@2|Bacteria,1VY2K@1239|Firmicutes,252G9@186801|Clostridia,42KW5@68298|Syntrophomonadaceae	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GDHHQS3_k127_6203069_5	1306990.BARG01000120_gene10162	2.595e-15	83.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
GDHHQS3_k127_6203069_8	315749.Bcer98_2623	3.652e-06	51.0	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GDHHQS3_k127_6203069_2	485913.Krac_6882	2.488e-65	238.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
GDHHQS3_k127_6203069_1	479434.Sthe_0322	3.206e-94	321.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GDHHQS3_k127_6203069_0	926569.ANT_03460	1.12e-241	761.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GDHHQS3_k127_6203069_3	1227739.Hsw_0573	3.651e-38	153.0	2E3VP@1|root,32YSV@2|Bacteria,4NV28@976|Bacteroidetes,47S3V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6203069_4	1121382.JQKG01000035_gene3860	1.188e-18	89.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_6204970_0	926569.ANT_08650	1.085e-114	376.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS3_k127_6204970_7	926569.ANT_08630	1.022e-46	171.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_6204970_1	926569.ANT_08620	1.181e-90	307.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GDHHQS3_k127_6204970_18	4081.Solyc11g005080.1.1	2.859e-09	69.0	COG0823@1|root,2QPTW@2759|Eukaryota,37K0C@33090|Viridiplantae,3G81Z@35493|Streptophyta,44BSE@71274|asterids	35493|Streptophyta	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
GDHHQS3_k127_6204970_19	1123269.NX02_05170	2.121e-07	63.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales	204457|Sphingomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_6204970_12	383372.Rcas_4165	8.724e-20	101.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6204970_14	383372.Rcas_4165	1.629e-15	89.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6204970_2	530564.Psta_1560	2.384e-81	288.0	2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6204970_20	357808.RoseRS_3879	3.567e-07	61.0	2ET4Z@1|root,33KP2@2|Bacteria,2G97T@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6204970_6	316274.Haur_0717	4.087e-48	186.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GDHHQS3_k127_6204970_9	324602.Caur_0294	6.615e-35	152.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,Cu_amine_oxidN1
GDHHQS3_k127_6204970_3	370438.PTH_1658	4.615e-74	259.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,261U2@186807|Peptococcaceae	186801|Clostridia	P	PFAM ABC transporter	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS3_k127_6204970_4	391623.TERMP_00693	2.716e-63	227.0	COG1122@1|root,arCOG00202@2157|Archaea,2Y7MJ@28890|Euryarchaeota,243GS@183968|Thermococci	183968|Thermococci	P	ATP-binding protein	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GDHHQS3_k127_6204970_5	1395513.P343_13320	1.854e-60	219.0	COG0619@1|root,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GDHHQS3_k127_6204970_8	1395513.P343_13325	1.256e-44	169.0	COG3447@1|root,COG3447@2|Bacteria	2|Bacteria	T	MASE1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HATPase_c,HisKA,MASE1,PAS_3,PAS_9
GDHHQS3_k127_6204970_16	1043205.AFYF01000099_gene628	6.782e-10	63.0	COG4422@1|root,COG4422@2|Bacteria,2GJHQ@201174|Actinobacteria,4FJDI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_6204970_17	864702.OsccyDRAFT_1813	6.814e-10	60.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria,1HBD3@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_6204970_13	41431.PCC8801_4326	2.014e-19	91.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria,3KJ1I@43988|Cyanothece	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_6204970_21	1123355.JHYO01000038_gene141	0.0002035	46.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,36YK2@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_6204970_10	32057.KB217478_gene7041	1.573e-26	113.0	COG1669@1|root,COG1669@2|Bacteria,1G7R5@1117|Cyanobacteria,1HQ1F@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GDHHQS3_k127_6204970_11	1541065.JRFE01000019_gene3227	1.73e-24	104.0	COG1598@1|root,COG1598@2|Bacteria,1GF2K@1117|Cyanobacteria,3VKUB@52604|Pleurocapsales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_623818_5	56780.SYN_00054	6.164e-45	167.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria,2MS9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS3_k127_623818_4	926569.ANT_27760	3.14e-71	248.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GDHHQS3_k127_623818_3	1128421.JAGA01000002_gene1719	6.696e-103	340.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_623818_1	926569.ANT_02630	7.39e-123	402.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GDHHQS3_k127_623818_2	926569.ANT_02640	4.412e-117	383.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_623818_0	926569.ANT_02650	6.875e-130	419.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_6244312_3	926569.ANT_04110	3.238e-40	155.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GDHHQS3_k127_6244312_1	926569.ANT_14700	2.425e-112	372.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_6244312_2	1462527.CCDM010000001_gene1748	5.366e-66	234.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,23K0V@182709|Oceanobacillus	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GDHHQS3_k127_6244312_0	926569.ANT_14720	1.273e-221	694.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GDHHQS3_k127_6269385_11	756883.Halar_2402	2.051e-67	238.0	COG3335@1|root,arCOG03965@1|root,arCOG02127@2157|Archaea,arCOG03965@2157|Archaea	2157|Archaea	S	DDE superfamily endonuclease	-	-	-	ko:K07494,ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
GDHHQS3_k127_6269385_18	306281.AJLK01000240_gene2864	7.014e-27	115.0	COG3415@1|root,COG3415@2|Bacteria,1GKNF@1117|Cyanobacteria,1JMRR@1189|Stigonemataceae	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
GDHHQS3_k127_6269385_19	471854.Dfer_4011	3.786e-26	112.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_6269385_17	1121935.AQXX01000142_gene2278	2.585e-27	114.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1XR3Y@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
GDHHQS3_k127_6269385_16	926569.ANT_04290	1.112e-29	122.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_6269385_8	926554.KI912637_gene3425	3.265e-77	270.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS3_k127_6269385_15	1191523.MROS_0663	2.315e-32	136.0	COG3358@1|root,COG3358@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS3_k127_6269385_13	525904.Tter_2170	3.782e-46	173.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS3_k127_6269385_7	1245471.PCA10_18760	3.527e-99	334.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1S070@1236|Gammaproteobacteria,1YF9G@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS3_k127_6269385_21	1297742.A176_03361	8.967e-14	76.0	COG0784@1|root,COG0784@2|Bacteria,1QVVE@1224|Proteobacteria,43520@68525|delta/epsilon subdivisions,2X94G@28221|Deltaproteobacteria,2Z1VC@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_6269385_0	926569.ANT_04250	3.053e-280	874.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
GDHHQS3_k127_6269385_2	926550.CLDAP_40520	5.854e-194	614.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GDHHQS3_k127_6269385_4	1434325.AZQN01000003_gene2515	2.02e-144	475.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GDHHQS3_k127_6269385_6	1191523.MROS_1853	4.191e-116	387.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GDHHQS3_k127_6269385_14	926569.ANT_16370	3.829e-35	144.0	COG0406@1|root,COG0406@2|Bacteria,2G7D2@200795|Chloroflexi	200795|Chloroflexi	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS3_k127_6269385_20	1123371.ATXH01000010_gene752	7.16e-22	96.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GDHHQS3_k127_6269385_22	113355.CM001775_gene2001	1.542e-13	73.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6269385_3	1007103.AFHW01000087_gene6320	1.147e-165	530.0	COG0179@1|root,COG0179@2|Bacteria,1VRIW@1239|Firmicutes,4HUFK@91061|Bacilli,26U89@186822|Paenibacillaceae	91061|Bacilli	Q	Fumarylacetoacetase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,FAA_hydrolase_N
GDHHQS3_k127_6269385_10	1218173.BALCAV_0201270	9.686e-68	241.0	COG0124@1|root,COG0124@2|Bacteria,1TY75@1239|Firmicutes,4I7AE@91061|Bacilli,1ZGKB@1386|Bacillus	91061|Bacilli	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6269385_9	1127673.GLIP_2427	1.051e-68	244.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,466I8@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
GDHHQS3_k127_6269385_5	1519464.HY22_00065	9.229e-125	406.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_6269385_24	694427.Palpr_2992	1.45e-08	61.0	2FGBF@1|root,3487S@2|Bacteria,4P5EM@976|Bacteroidetes,2FYM9@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6269385_1	383372.Rcas_0234	2.922e-195	612.0	COG3938@1|root,COG3938@2|Bacteria,2G5PY@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the proline racemase family	-	-	5.1.1.4,5.1.1.8	ko:K01777,ko:K12658	ko00330,ko01100,map00330,map01100	-	R01255,R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
GDHHQS3_k127_6269385_23	264732.Moth_2299	7.235e-09	59.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_627810_4	479434.Sthe_2726	8.703e-29	117.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GDHHQS3_k127_627810_10	331678.Cphamn1_1576	0.0002032	50.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_627810_5	1123392.AQWL01000002_gene2007	9.613e-26	116.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,1KRQF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
GDHHQS3_k127_627810_9	357808.RoseRS_3899	3.293e-07	58.0	2A42V@1|root,30SMT@2|Bacteria,2GAGJ@200795|Chloroflexi,3761P@32061|Chloroflexia	32061|Chloroflexia	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
GDHHQS3_k127_627810_3	246969.TAM4_452	8.597e-41	156.0	COG1720@1|root,arCOG00761@2157|Archaea,2XY3D@28890|Euryarchaeota,2440R@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GDHHQS3_k127_627810_1	926569.ANT_04910	1.141e-53	192.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GDHHQS3_k127_627810_6	1048834.TC41_0736	1.034e-20	99.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HGJC@91061|Bacilli,27A6M@186823|Alicyclobacillaceae	91061|Bacilli	Q	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_627810_0	1196322.A370_03935	4.447e-66	230.0	COG2128@1|root,COG2128@2|Bacteria,1V55P@1239|Firmicutes,24HT6@186801|Clostridia,36RNR@31979|Clostridiaceae	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GDHHQS3_k127_627810_2	326427.Cagg_3325	2.545e-47	175.0	COG3118@1|root,COG3118@2|Bacteria,2G70B@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function (DUF2892)	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF2892,Thioredoxin
GDHHQS3_k127_627810_7	926569.ANT_03020	3.694e-14	74.0	2BH31@1|root,32B3S@2|Bacteria,2G9T0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GDHHQS3_k127_627810_8	1353537.TP2_16355	6.139e-13	80.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2XNXZ@285107|Thioclava	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GDHHQS3_k127_6283868_19	926569.ANT_22190	1.826e-18	93.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_6283868_20	926569.ANT_22190	9.79e-13	77.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_6283868_10	926569.ANT_22190	3.506e-92	318.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_6283868_16	926569.ANT_15080	1.075e-27	124.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_6283868_15	926569.ANT_22190	6.454e-34	145.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GDHHQS3_k127_6283868_17	926569.ANT_12310	3.094e-24	108.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GDHHQS3_k127_6283868_12	926569.ANT_12300	1.666e-50	187.0	COG3293@1|root,COG3293@2|Bacteria,2G9EK@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GDHHQS3_k127_6283868_13	316274.Haur_4998	3.373e-48	199.0	COG3210@1|root,COG3391@1|root,COG5184@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,CHU_C,Calx-beta,DUF4347,FG-GAP,HYR,VCBS
GDHHQS3_k127_6283868_18	1223523.H340_23758	3.718e-23	104.0	2FG67@1|root,3482N@2|Bacteria,2GV16@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6283868_6	1223523.H340_23763	1.535e-106	355.0	COG1376@1|root,COG2304@1|root,COG1376@2|Bacteria,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
GDHHQS3_k127_6283868_1	1128421.JAGA01000002_gene342	2.2e-189	605.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GDHHQS3_k127_6283868_3	448385.sce7756	6.673e-152	488.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,42P6E@68525|delta/epsilon subdivisions,2WISH@28221|Deltaproteobacteria,2YV40@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_6283868_4	448385.sce7757	6.38e-145	468.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42Q6K@68525|delta/epsilon subdivisions,2WM2U@28221|Deltaproteobacteria,2YX9P@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GDHHQS3_k127_6283868_5	1254432.SCE1572_44715	6.179e-113	376.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS3_k127_6283868_11	1192034.CAP_7857	1.216e-56	210.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GDHHQS3_k127_6283868_2	926569.ANT_28050	6.131e-165	529.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_6283868_8	926569.ANT_28060	7.896e-103	340.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GDHHQS3_k127_6283868_9	926569.ANT_00870	1.401e-96	330.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
GDHHQS3_k127_6283868_7	926569.ANT_00860	8.227e-106	360.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
GDHHQS3_k127_6283868_14	926569.ANT_26660	3.589e-40	150.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GDHHQS3_k127_6283868_0	926569.ANT_26670	6.123e-248	775.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GDHHQS3_k127_6386791_16	32051.SynWH7803_0583	1.31e-05	56.0	COG0531@1|root,COG0531@2|Bacteria,1G33D@1117|Cyanobacteria,1H04V@1129|Synechococcus	1117|Cyanobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GDHHQS3_k127_6386791_0	443143.GM18_2837	1.025e-257	824.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,43S1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,PTS_EIIA_2
GDHHQS3_k127_6386791_8	1449050.JNLE01000003_gene2625	1.484e-59	213.0	COG0569@1|root,COG0569@2|Bacteria,1VBDR@1239|Firmicutes,25CEP@186801|Clostridia,36VPV@31979|Clostridiaceae	186801|Clostridia	P	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_6386791_5	357808.RoseRS_3062	3.246e-73	254.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,377FQ@32061|Chloroflexia	32061|Chloroflexia	C	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GDHHQS3_k127_6386791_12	1254432.SCE1572_05510	5.563e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GDHHQS3_k127_6386791_11	1382356.JQMP01000003_gene1897	1.083e-40	156.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GDHHQS3_k127_6386791_15	56780.SYN_00981	2.379e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657,ko:K07659,ko:K07664,ko:K11329	ko02020,ko02026,map02020,map02026	M00434,M00445,M00450,M00467,M00645,M00646,M00648,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_6386791_10	926569.ANT_08670	2.395e-51	188.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GDHHQS3_k127_6386791_13	926569.ANT_08660	6.092e-32	127.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GDHHQS3_k127_6386791_6	926569.ANT_18710	1.26e-65	228.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GDHHQS3_k127_6386791_2	926569.ANT_18700	7.539e-118	418.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GDHHQS3_k127_6386791_1	926569.ANT_22870	3.569e-188	596.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GDHHQS3_k127_6386791_3	926569.ANT_20800	4.799e-96	325.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi	200795|Chloroflexi	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6386791_14	56780.SYN_03642	1.725e-29	120.0	COG1225@1|root,COG1225@2|Bacteria,1P69S@1224|Proteobacteria,432W3@68525|delta/epsilon subdivisions,2WXMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_6386791_17	926569.ANT_19750	1.884e-05	48.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GDHHQS3_k127_6386791_4	926550.CLDAP_28300	2.988e-90	307.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
GDHHQS3_k127_6386791_7	926550.CLDAP_20430	6.167e-63	224.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
GDHHQS3_k127_6386791_9	526227.Mesil_3164	2.085e-58	207.0	COG1573@1|root,COG1573@2|Bacteria,1WI63@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM Uracil DNA glycosylase superfamily	-	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_6408358_4	1464048.JNZS01000001_gene137	1.72e-08	64.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6408358_5	1267535.KB906767_gene5181	1.43e-07	62.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GJ@57723|Acidobacteria,2JJ01@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GDHHQS3_k127_6408358_1	765420.OSCT_2914	5.968e-125	417.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS3_k127_6408358_0	926569.ANT_30160	1.104e-191	605.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_6408358_2	926569.ANT_25670	2.113e-50	187.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
GDHHQS3_k127_64147_0	357808.RoseRS_0893	7.822e-95	323.0	COG3677@1|root,COG3677@2|Bacteria,2G6SJ@200795|Chloroflexi,3772U@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_64147_2	102125.Xen7305DRAFT_00034050	2.078e-44	162.0	COG3093@1|root,COG3093@2|Bacteria,1G82A@1117|Cyanobacteria,3VN4Y@52604|Pleurocapsales	1117|Cyanobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GDHHQS3_k127_64147_3	237368.SCABRO_00944	2.18e-44	162.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
GDHHQS3_k127_64147_4	926569.ANT_16040	2.701e-33	131.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GDHHQS3_k127_64147_5	926569.ANT_16030	6.548e-23	99.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GDHHQS3_k127_64147_1	926569.ANT_16020	7.361e-47	177.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GDHHQS3_k127_64147_7	926569.ANT_16010	8.232e-10	61.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GDHHQS3_k127_64360_5	1296416.JACB01000006_gene547	9.532e-110	361.0	COG0384@1|root,COG0384@2|Bacteria,4PGX7@976|Bacteroidetes,1IM7Z@117743|Flavobacteriia,2YKHA@290174|Aquimarina	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GDHHQS3_k127_64360_3	926569.ANT_02950	3.146e-188	595.0	COG0402@1|root,COG0402@2|Bacteria,2G6K7@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
GDHHQS3_k127_64360_8	1170562.Cal6303_3251	1.276e-87	301.0	COG3850@1|root,COG3850@2|Bacteria,1GJRF@1117|Cyanobacteria,1HR3E@1161|Nostocales	1117|Cyanobacteria	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
GDHHQS3_k127_64360_1	1049564.TevJSym_af00690	1.707e-266	837.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,1RNTD@1236|Gammaproteobacteria,1J9TP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
GDHHQS3_k127_64360_6	869210.Marky_1615	1.129e-99	329.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
GDHHQS3_k127_64360_0	926569.ANT_22150	5.117e-279	867.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_64360_16	136273.GY22_10270	0.0002115	50.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,1W966@1268|Micrococcaceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS3_k127_64360_15	1121877.JQKF01000025_gene821	4.279e-05	51.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4CNSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS3_k127_64360_7	246194.CHY_1370	4.438e-90	304.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,42H51@68295|Thermoanaerobacterales	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
GDHHQS3_k127_64360_13	246194.CHY_1371	1.131e-10	66.0	COG2142@1|root,COG2142@2|Bacteria	2|Bacteria	C	succinate dehydrogenase activity	sdhD	-	-	ko:K00242,ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS3_k127_64360_11	1459636.NTE_01593	2.708e-20	96.0	COG2009@1|root,arCOG02244@2157|Archaea,41SKZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GDHHQS3_k127_64360_2	246194.CHY_1373	5.862e-242	759.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,42FNP@68295|Thermoanaerobacterales	186801|Clostridia	C	fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_64360_9	1005048.CFU_2831	3.228e-41	154.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,474RD@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
GDHHQS3_k127_64360_12	485913.Krac_3124	5.988e-13	76.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_64360_10	196162.Noca_2943	2.662e-34	139.0	COG2197@1|root,COG2197@2|Bacteria,2IBDE@201174|Actinobacteria	201174|Actinobacteria	T	Two component transcriptional regulator, luxr family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_64360_14	29486.NJ56_07195	2.602e-06	49.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,41DQB@629|Yersinia	1236|Gammaproteobacteria	C	Isocitrate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
GDHHQS3_k127_64360_4	1192034.CAP_3742	5.796e-142	458.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GDHHQS3_k127_6453792_2	926569.ANT_27750	1.066e-122	398.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GDHHQS3_k127_6453792_0	316274.Haur_3999	2.053e-164	526.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_6453792_1	1128421.JAGA01000002_gene1716	1.664e-125	409.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GDHHQS3_k127_6453792_3	765420.OSCT_1170	1.145e-118	390.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
GDHHQS3_k127_6453792_4	926569.ANT_01750	5.988e-79	268.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
GDHHQS3_k127_6460_2	927677.ALVU02000001_gene3793	1.39e-55	209.0	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1FZWU@1117|Cyanobacteria,1H61N@1142|Synechocystis	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
GDHHQS3_k127_6460_1	926569.ANT_11620	1.784e-60	215.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GDHHQS3_k127_6460_0	926569.ANT_11630	4.454e-118	388.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GDHHQS3_k127_6460_4	439235.Dalk_2449	1.502e-38	162.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6460_3	479434.Sthe_0091	5.266e-44	165.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_6659733_5	383372.Rcas_3687	2.846e-47	172.0	COG3744@1|root,COG3744@2|Bacteria,2G9CV@200795|Chloroflexi,377FA@32061|Chloroflexia	32061|Chloroflexia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_6659733_6	28072.Nos7524_3875	7.844e-10	62.0	COG4118@1|root,COG4118@2|Bacteria,1G94N@1117|Cyanobacteria	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,PhdYeFM_antitox
GDHHQS3_k127_6659733_0	765420.OSCT_2354	5.276e-158	503.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GDHHQS3_k127_6659733_1	926569.ANT_06170	1.308e-137	443.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_6659733_4	926569.ANT_06160	1.57e-59	217.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GDHHQS3_k127_6760345_0	483219.LILAB_07185	3.083e-66	236.0	COG3440@1|root,COG3440@2|Bacteria,1PY8G@1224|Proteobacteria,4355Z@68525|delta/epsilon subdivisions,2WZGW@28221|Deltaproteobacteria,2Z24G@29|Myxococcales	28221|Deltaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
GDHHQS3_k127_6760345_1	62928.azo0356	2.475e-21	95.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2VTKI@28216|Betaproteobacteria,2KX5S@206389|Rhodocyclales	206389|Rhodocyclales	L	Very short patch repair endonuclease	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
GDHHQS3_k127_6777747_18	926569.ANT_13390	2.502e-19	88.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS3_k127_6777747_9	335543.Sfum_4027	1.54e-103	350.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
GDHHQS3_k127_6777747_6	1463895.JODA01000001_gene477	7.046e-144	466.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
GDHHQS3_k127_6777747_10	326427.Cagg_2948	1.26e-85	293.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi,375I3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_6777747_23	395493.BegalDRAFT_0018	3.863e-07	57.0	2DSPU@1|root,33GZC@2|Bacteria,1NJ5W@1224|Proteobacteria,1SHAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GDHHQS3_k127_6777747_19	1151118.KB895783_gene3917	1.527e-18	90.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GDHHQS3_k127_6777747_21	1385511.N783_09260	4.796e-11	67.0	2E4BN@1|root,32Z79@2|Bacteria,1VQQV@1239|Firmicutes,4HRU8@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6777747_20	1449076.JOOE01000001_gene1907	4.773e-14	76.0	COG1359@1|root,COG1359@2|Bacteria,1N1I5@1224|Proteobacteria,2UCV3@28211|Alphaproteobacteria,2K64T@204457|Sphingomonadales	204457|Sphingomonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_6777747_3	1121920.AUAU01000013_gene1701	1.511e-199	631.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GDHHQS3_k127_6777747_0	1121920.AUAU01000013_gene1700	0.0	1149.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485,iIT341.HP0212	M20_dimer,Peptidase_M20
GDHHQS3_k127_6777747_14	316274.Haur_2320	6.163e-53	192.0	COG1670@1|root,COG1670@2|Bacteria,2G9NS@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GDHHQS3_k127_6777747_15	926550.CLDAP_03420	4.882e-48	179.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GDHHQS3_k127_6777747_13	525904.Tter_2279	3.583e-65	238.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
GDHHQS3_k127_6777747_2	926569.ANT_00900	1.064e-199	638.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GDHHQS3_k127_6777747_12	316274.Haur_3817	1.287e-65	237.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_6777747_17	1499967.BAYZ01000159_gene478	1.797e-24	113.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS3_k127_6777747_7	926569.ANT_02010	1.075e-123	401.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS3_k127_6777747_16	378806.STAUR_3873	2.77e-46	177.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,42UMK@68525|delta/epsilon subdivisions,2WQNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GDHHQS3_k127_6777747_5	926569.ANT_02020	2.097e-146	470.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GDHHQS3_k127_6777747_11	1122223.KB890692_gene3011	3.549e-77	267.0	COG4106@1|root,COG4106@2|Bacteria,1WMC7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Methyltransferase domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
GDHHQS3_k127_6777747_1	926569.ANT_02040	1.207e-245	767.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GDHHQS3_k127_6777747_24	913848.AELK01000125_gene1776	4.751e-07	54.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_6777747_8	485913.Krac_2372	1.153e-106	357.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6777747_4	926550.CLDAP_02910	5.332e-154	500.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
GDHHQS3_k127_6777747_22	926569.ANT_16050	3.988e-10	61.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GDHHQS3_k127_6791698_0	926569.ANT_00490	5.509e-188	600.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
GDHHQS3_k127_6791698_2	926569.ANT_30470	4.015e-57	212.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
GDHHQS3_k127_6798003_8	688270.Celal_2908	8.457e-14	73.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia,1F997@104264|Cellulophaga	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS3_k127_6798003_6	383372.Rcas_2861	1.721e-16	81.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GDHHQS3_k127_6798003_2	1116472.MGMO_8c00610	6.367e-38	146.0	COG1487@1|root,COG1487@2|Bacteria,1QU3C@1224|Proteobacteria,1T4XA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GDHHQS3_k127_6798003_9	1487953.JMKF01000016_gene2553	7.791e-10	61.0	2E46G@1|root,32Z2E@2|Bacteria,1G8V4@1117|Cyanobacteria,1HGBS@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6798003_7	309798.COPRO5265_1458	2.463e-15	90.0	2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6798003_0	926569.ANT_06480	6.914e-188	602.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6798003_4	1492738.FEM21_17350	1.977e-28	120.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia,2NWDS@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GDHHQS3_k127_6798003_3	272558.10176004	3.889e-33	139.0	COG0457@1|root,COG0457@2|Bacteria,1U9ZE@1239|Firmicutes,4IK7A@91061|Bacilli,1ZFKG@1386|Bacillus	91061|Bacilli	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
GDHHQS3_k127_6798003_1	926569.ANT_06470	1.724e-132	428.0	COG2089@1|root,COG2089@2|Bacteria,2G8IV@200795|Chloroflexi	200795|Chloroflexi	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
GDHHQS3_k127_6798003_5	585530.HMPREF0183_1855	2.912e-19	89.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria,2I2ET@201174|Actinobacteria,4F90H@85019|Brevibacteriaceae	201174|Actinobacteria	M	Cytidylyltransferase	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Hydrolase_3
GDHHQS3_k127_6898739_0	926569.ANT_27450	2.308e-161	531.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
GDHHQS3_k127_6898739_6	765420.OSCT_2692	2.957e-28	118.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
GDHHQS3_k127_6898739_5	926569.ANT_27430	1.255e-36	141.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS3_k127_6898739_3	472759.Nhal_0728	5.557e-54	195.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1S4GM@1236|Gammaproteobacteria,1WYNP@135613|Chromatiales	135613|Chromatiales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_6898739_2	477974.Daud_1728	9.61e-79	280.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GDHHQS3_k127_6898739_4	926559.JoomaDRAFT_3556	4.242e-45	191.0	COG1361@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,1IKB7@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB
GDHHQS3_k127_6898739_1	713586.KB900536_gene2793	1.098e-125	456.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,1T2IX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6906151_2	357808.RoseRS_0140	2.959e-44	168.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,375V8@32061|Chloroflexia	32061|Chloroflexia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GDHHQS3_k127_6906151_1	926569.ANT_28850	2.449e-55	196.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
GDHHQS3_k127_6906151_3	765420.OSCT_0628	7.543e-16	83.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
GDHHQS3_k127_6906151_0	383372.Rcas_2918	1.215e-70	251.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GDHHQS3_k127_6906151_4	1313421.JHBV01000016_gene5604	1.273e-12	72.0	2DHAX@1|root,32U8Z@2|Bacteria	2|Bacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
GDHHQS3_k127_6907202_5	1123023.JIAI01000004_gene7873	4e-61	218.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_6907202_23	1267005.KB911261_gene2365	0.0009181	45.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS3_k127_6907202_21	293227.XP_008717418.1	1.183e-07	56.0	2D1P4@1|root,2SIRU@2759|Eukaryota,3A09S@33154|Opisthokonta,3P2HR@4751|Fungi,3QUEK@4890|Ascomycota,20KFE@147545|Eurotiomycetes,3MU05@451870|Chaetothyriomycetidae	4751|Fungi	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GDHHQS3_k127_6907202_9	1218352.B597_021855	3.105e-47	185.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1SJQW@1236|Gammaproteobacteria,1Z2NE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_6907202_4	1242864.D187_003344	4.279e-76	274.0	COG1064@1|root,COG1064@2|Bacteria,1RAY7@1224|Proteobacteria	1224|Proteobacteria	S	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_6907202_17	1121271.AUCM01000004_gene1030	8.822e-21	97.0	COG3427@1|root,COG3427@2|Bacteria,1R77T@1224|Proteobacteria,2U8TZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
GDHHQS3_k127_6907202_6	1123504.JQKD01000007_gene3483	1.35e-54	202.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,4AJ77@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GDHHQS3_k127_6907202_0	309801.trd_A0069	5.55e-206	663.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_6907202_3	485913.Krac_9361	6.635e-83	284.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_6907202_18	311403.Arad_7196	3.598e-18	89.0	COG0662@1|root,COG0662@2|Bacteria,1P7SH@1224|Proteobacteria,2UW18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_6907202_22	1367847.JCM7686_pAMI4p288	0.0002116	52.0	COG3971@1|root,COG3971@2|Bacteria,1R3UP@1224|Proteobacteria,2TQR2@28211|Alphaproteobacteria,2PV2T@265|Paracoccus	28211|Alphaproteobacteria	Q	hydratase decarboxylase	-	-	4.2.1.80	ko:K02509,ko:K02554	ko00350,ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00350,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04132,R04781,R06897	RC00750,RC01213,RC01615,RC02595	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
GDHHQS3_k127_6907202_10	2754.EH55_00110	1.041e-45	171.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32470	Fer2,Fer2_2
GDHHQS3_k127_6907202_15	1121422.AUMW01000012_gene2992	6.592e-37	147.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_6907202_19	269799.Gmet_1045	8.809e-14	74.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,43S6G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_6907202_7	926569.ANT_25930	1.451e-49	196.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,VanY,YkuD
GDHHQS3_k127_6907202_12	1396418.BATQ01000179_gene3160	2.735e-41	173.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,46US9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_6907202_14	215803.DB30_0942	4.204e-38	159.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,4345Q@68525|delta/epsilon subdivisions,2X1U5@28221|Deltaproteobacteria,2YY1H@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
GDHHQS3_k127_6907202_20	305700.B447_12889	1.41e-10	66.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GDHHQS3_k127_6907202_2	316274.Haur_1474	6.018e-134	434.0	COG3437@1|root,COG3437@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
GDHHQS3_k127_6907202_8	926550.CLDAP_25540	5.868e-49	182.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_6907202_16	1245471.PCA10_33980	1.051e-28	128.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1YJ13@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Cache 3/Cache 2 fusion domain	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
GDHHQS3_k127_6907202_11	926550.CLDAP_13880	1.992e-43	172.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768,ko:K20977	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00820	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HATPase_c_2,HisKA,Response_reg,SpoIIE
GDHHQS3_k127_6907202_1	272123.Anacy_0233	7.117e-145	519.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1HKS3@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GDHHQS3_k127_6907202_13	1121448.DGI_2662	1.847e-39	172.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
GDHHQS3_k127_6973620_11	1150398.JIBJ01000013_gene2549	2.616e-55	207.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
GDHHQS3_k127_6973620_20	760568.Desku_1179	1.043e-37	156.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GDHHQS3_k127_6973620_18	926569.ANT_11610	5.974e-42	160.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
GDHHQS3_k127_6973620_3	861299.J421_2874	2.571e-142	467.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
GDHHQS3_k127_6973620_16	926569.ANT_20600	1.758e-46	173.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_6973620_2	926569.ANT_14490	6.786e-175	560.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GDHHQS3_k127_6973620_1	926569.ANT_14510	4.881e-294	918.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GDHHQS3_k127_6973620_7	439235.Dalk_1565	5.184e-77	267.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GDHHQS3_k127_6973620_17	926550.CLDAP_05380	2.842e-44	168.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GDHHQS3_k127_6973620_21	497964.CfE428DRAFT_3478	4.184e-33	139.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
GDHHQS3_k127_6973620_19	497964.CfE428DRAFT_3478	8.659e-40	157.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
GDHHQS3_k127_6973620_8	926550.CLDAP_11640	1.304e-70	250.0	COG3608@1|root,COG3608@2|Bacteria,2G71G@200795|Chloroflexi	200795|Chloroflexi	S	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	-
GDHHQS3_k127_6973620_6	926569.ANT_15370	1.966e-101	346.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS3_k127_6973620_14	926569.ANT_14530	6.973e-50	184.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GDHHQS3_k127_6973620_9	1123274.KB899410_gene3489	1.483e-67	241.0	COG1597@1|root,COG1597@2|Bacteria,2J9G6@203691|Spirochaetes	203691|Spirochaetes	I	PFAM Diacylglycerol kinase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS3_k127_6973620_12	889378.Spiaf_2505	2.63e-54	198.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51,2.7.4.25	ko:K00655,ko:K00945	ko00240,ko00561,ko00564,ko01100,ko01110,map00240,map00561,map00564,map01100,map01110	M00052,M00089	R00158,R00512,R01665,R02241,R09381	RC00002,RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GDHHQS3_k127_6973620_22	679937.Bcop_2214	2.846e-32	130.0	COG0454@1|root,COG0456@2|Bacteria,4NSH4@976|Bacteroidetes,2FUSG@200643|Bacteroidia,4AQU2@815|Bacteroidaceae	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
GDHHQS3_k127_6973620_15	1034943.BN1094_02561	3.963e-48	181.0	COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,1S88D@1236|Gammaproteobacteria,1JDWD@118969|Legionellales	118969|Legionellales	I	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	lidK	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GDHHQS3_k127_6973620_0	926569.ANT_22850	0.0	1556.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GDHHQS3_k127_6973620_10	926569.ANT_25400	4.269e-57	208.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
GDHHQS3_k127_6973620_4	926569.ANT_16650	3.011e-142	458.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GDHHQS3_k127_6973620_5	926569.ANT_16640	3.602e-124	404.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GDHHQS3_k127_6973620_13	926569.ANT_15100	3.068e-52	186.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GDHHQS3_k127_6996840_0	316274.Haur_3362	6.193e-65	228.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GDHHQS3_k127_6996840_3	357808.RoseRS_0453	1.198e-50	185.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GDHHQS3_k127_6996840_2	926569.ANT_16060	1.723e-53	194.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GDHHQS3_k127_6996840_1	926569.ANT_26470	4.262e-57	205.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
GDHHQS3_k127_7021128_6	1242864.D187_000998	5.563e-60	213.0	28PN2@1|root,2ZCAV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7021128_1	926569.ANT_14670	2.151e-185	598.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_7021128_10	926569.ANT_14650	9.165e-23	103.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GDHHQS3_k127_7021128_9	926550.CLDAP_18740	2.764e-47	183.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GDHHQS3_k127_7021128_7	321332.CYB_2125	1.095e-59	216.0	COG0765@1|root,COG0765@2|Bacteria,1G0FV@1117|Cyanobacteria,1H13F@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	-	-	-	ko:K02029,ko:K02030,ko:K09971,ko:K17062	ko02010,map02010	M00232,M00236,M00587	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.12,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1,SBP_bac_3
GDHHQS3_k127_7021128_4	1265505.ATUG01000001_gene4316	6.037e-89	300.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2MICA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
GDHHQS3_k127_7021128_5	1163407.UU7_04737	2.344e-77	266.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GDHHQS3_k127_7021128_2	926569.ANT_11730	5.841e-112	371.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GDHHQS3_k127_7021128_8	926569.ANT_11720	2.784e-53	195.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GDHHQS3_k127_7021128_0	926569.ANT_15410	0.0	1084.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
GDHHQS3_k127_7021128_3	485916.Dtox_2814	1.476e-93	319.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GDHHQS3_k127_7043749_0	309801.trd_1109	2.005e-241	769.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GDHHQS3_k127_7043749_2	926550.CLDAP_00050	1.323e-115	376.0	COG0588@1|root,COG0588@2|Bacteria,2G822@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GDHHQS3_k127_7043749_1	479434.Sthe_2294	2.691e-223	724.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
GDHHQS3_k127_7043749_8	1461580.CCAS010000016_gene1937	2.811e-14	83.0	COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,1ZRJ5@1386|Bacillus	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	ypmR1	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GDHHQS3_k127_7043749_4	926569.ANT_30890	1.911e-52	193.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
GDHHQS3_k127_7043749_5	926550.CLDAP_28610	7.093e-47	176.0	COG0566@1|root,COG0566@2|Bacteria,2G8WM@200795|Chloroflexi	200795|Chloroflexi	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
GDHHQS3_k127_7043749_6	1279009.ADICEAN_03917	5.581e-26	110.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,47RWW@768503|Cytophagia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
GDHHQS3_k127_7043749_3	631454.N177_1227	6.931e-69	248.0	COG2159@1|root,COG2159@2|Bacteria,1NAC7@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GDHHQS3_k127_7043749_7	926569.ANT_28120	3.394e-23	108.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
GDHHQS3_k127_7056058_0	1122994.AUFR01000022_gene333	5.994e-158	515.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GDHHQS3_k127_7056058_3	644548.SCNU_14836	3.001e-58	206.0	2DXPV@1|root,32V3V@2|Bacteria,2IDU1@201174|Actinobacteria,4GG6T@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7056058_1	1157632.AQWQ01000003_gene2066	7.708e-109	361.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GDHHQS3_k127_7056058_5	981383.AEWH01000063_gene1955	1.485e-34	144.0	COG0842@1|root,COG0842@2|Bacteria,1V0J8@1239|Firmicutes,4HEBH@91061|Bacilli	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_7056058_4	1122138.AQUZ01000039_gene8019	9.973e-40	158.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GDHHQS3_k127_7056058_2	926569.ANT_13390	9.009e-87	290.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS3_k127_7068583_3	748727.CLJU_c18020	3.296e-07	57.0	COG3103@1|root,COG4991@2|Bacteria,1VBMC@1239|Firmicutes,24CJ7@186801|Clostridia,36HBQ@31979|Clostridiaceae	186801|Clostridia	T	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GDHHQS3_k127_7068583_0	688269.Theth_0229	2.897e-47	179.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_7068583_1	1385935.N836_35430	1.339e-23	106.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7068583_4	1121904.ARBP01000017_gene5075	3.863e-07	57.0	COG2730@1|root,COG3291@1|root,COG4625@1|root,COG5492@1|root,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4NJ9A@976|Bacteroidetes,47M79@768503|Cytophagia	976|Bacteroidetes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Big_2,F5_F8_type_C,LRR_5,Polysacc_deac_3
GDHHQS3_k127_7068583_2	1454007.JAUG01000120_gene727	1.135e-07	56.0	COG2253@1|root,COG2253@2|Bacteria,4NKE9@976|Bacteroidetes,1IRWJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GDHHQS3_k127_7068583_5	760568.Desku_0176	7.549e-05	48.0	2DNQS@1|root,32YKX@2|Bacteria,1VG7R@1239|Firmicutes,24R79@186801|Clostridia,262SB@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7073244_4	1341155.FSS13T_08740	2.007e-07	55.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8R@976|Bacteroidetes,1I3CY@117743|Flavobacteriia,2NW9C@237|Flavobacterium	976|Bacteroidetes	S	SRPBCC superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GDHHQS3_k127_7073244_3	1307761.L21SP2_3047	2.148e-60	224.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS3_k127_7073244_2	324602.Caur_1344	3.748e-65	235.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_7073244_0	926569.ANT_22790	9.906e-160	516.0	COG1271@1|root,COG1271@2|Bacteria,2G5TR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
GDHHQS3_k127_7073244_1	880073.Calab_0286	2.938e-97	324.0	COG1294@1|root,COG1294@2|Bacteria,2NS31@2323|unclassified Bacteria	2|Bacteria	C	PFAM Cytochrome bd ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120	Cyt_bd_oxida_II
GDHHQS3_k127_7078339_7	926569.ANT_22220	2.345e-30	120.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
GDHHQS3_k127_7078339_8	323848.Nmul_A0278	2.467e-14	86.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2VVZK@28216|Betaproteobacteria,372N5@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_7078339_1	357808.RoseRS_3747	9.041e-80	271.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GDHHQS3_k127_7078339_10	554065.XP_005847518.1	3.82e-11	71.0	2E3GZ@1|root,2SAJB@2759|Eukaryota,381P2@33090|Viridiplantae,34NDB@3041|Chlorophyta	3041|Chlorophyta	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
GDHHQS3_k127_7078339_6	264732.Moth_0570	3.856e-36	144.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GEY@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
GDHHQS3_k127_7078339_4	926569.ANT_01640	5.427e-51	186.0	COG0500@1|root,COG2226@2|Bacteria,2G8IN@200795|Chloroflexi	200795|Chloroflexi	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
GDHHQS3_k127_7078339_0	926550.CLDAP_27570	4.691e-163	521.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_7078339_3	926569.ANT_30890	2.198e-57	208.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
GDHHQS3_k127_7078339_2	1048983.EL17_23455	3.97e-58	209.0	28IG0@1|root,2Z8HI@2|Bacteria,4NR3P@976|Bacteroidetes,47TFI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7078339_5	357808.RoseRS_3606	5.157e-49	179.0	COG1011@1|root,COG1011@2|Bacteria,2G97P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GDHHQS3_k127_7089154_1	926569.ANT_11200	5.823e-118	395.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS3_k127_7089154_0	383372.Rcas_2438	4.446e-129	422.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GDHHQS3_k127_7089154_2	926569.ANT_14000	1.175e-69	240.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
GDHHQS3_k127_7093641_4	926569.ANT_08320	5.888e-85	284.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GDHHQS3_k127_7093641_6	926569.ANT_08330	5.254e-62	217.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GDHHQS3_k127_7093641_1	926569.ANT_08340	1.838e-197	622.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_7093641_9	1041930.Mtc_0416	6.774e-23	101.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y713@28890|Euryarchaeota,2NB3C@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GDHHQS3_k127_7093641_0	926569.ANT_08350	1.074e-299	939.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_7093641_2	926569.ANT_08360	2.051e-128	420.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GDHHQS3_k127_7093641_5	926569.ANT_08370	5.509e-72	246.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS3_k127_7093641_7	926569.ANT_08380	7.517e-41	157.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GDHHQS3_k127_7093641_8	926569.ANT_08390	6.068e-34	134.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GDHHQS3_k127_7093641_3	1379270.AUXF01000006_gene240	4.953e-109	367.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GDHHQS3_k127_7104822_2	1122609.AUGT01000003_gene2233	2.597e-26	111.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4DQ00@85009|Propionibacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GDHHQS3_k127_7104822_5	561230.PC1_2136	2.676e-15	83.0	2E8SS@1|root,3333I@2|Bacteria,1NF8M@1224|Proteobacteria,1SJ9Y@1236|Gammaproteobacteria,1MSH9@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7104822_0	316274.Haur_0632	1.585e-148	479.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi,3752Z@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GDHHQS3_k127_7104822_4	518766.Rmar_0410	2.246e-16	82.0	2EHRH@1|root,33BH9@2|Bacteria,4NXPJ@976|Bacteroidetes,1FJP5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
GDHHQS3_k127_7104822_3	880072.Desac_1288	8.456e-23	101.0	2E953@1|root,333DW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7104822_1	1254432.SCE1572_23415	3.67e-113	372.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2Z3AJ@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
GDHHQS3_k127_7127366_0	926569.ANT_06580	1.1e-69	238.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
GDHHQS3_k127_7127366_1	497965.Cyan7822_3361	1.411e-56	208.0	2DTTJ@1|root,32UVW@2|Bacteria,1GA7P@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GDHHQS3_k127_7127366_5	561175.KB894094_gene1539	1.426e-09	70.0	2DBRU@1|root,2ZANA@2|Bacteria,2GP2Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7127366_4	316274.Haur_2048	1.411e-14	78.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi,376XZ@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
GDHHQS3_k127_7127366_2	675817.VDA_002416	4.662e-38	148.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,1Y2TW@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
GDHHQS3_k127_7127366_3	316274.Haur_2046	9.498e-29	120.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
GDHHQS3_k127_7161015_6	926569.ANT_31060	1.588e-30	128.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_7161015_3	479434.Sthe_2033	1.64e-91	316.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_7161015_2	926569.ANT_06790	6.418e-116	379.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GDHHQS3_k127_7161015_4	926569.ANT_06780	3.203e-88	294.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
GDHHQS3_k127_7161015_1	926569.ANT_06770	1.108e-121	395.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_7161015_7	867845.KI911784_gene275	1.106e-09	62.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GDHHQS3_k127_7161015_5	926569.ANT_03770	5.653e-34	137.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GDHHQS3_k127_7161015_0	926569.ANT_06750	4.092e-192	607.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS3_k127_7199978_1	926569.ANT_16400	2.224e-141	466.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7199978_3	926569.ANT_16390	1.652e-42	160.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7199978_4	926569.ANT_18300	1.274e-28	119.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GDHHQS3_k127_7199978_0	926569.ANT_18310	0.0	1088.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GDHHQS3_k127_7199978_5	926569.ANT_18320	1.867e-22	100.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413,ko:K07719	ko02020,ko02030,map02020,map02030	M00506,M00518	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg,YcbB
GDHHQS3_k127_7199978_2	926569.ANT_18330	1.756e-59	210.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
GDHHQS3_k127_7218593_0	926569.ANT_29800	7.757e-91	303.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_7218593_2	926550.CLDAP_32470	2.5e-37	160.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_7218593_1	926550.CLDAP_32470	1.44e-40	169.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_7218593_3	290402.Cbei_1725	6.016e-08	57.0	COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,2483X@186801|Clostridia,36E3T@31979|Clostridiaceae	186801|Clostridia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GDHHQS3_k127_7260819_3	1306406.ASHX01000001_gene4469	2e-58	206.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF11,PKD,PPC
GDHHQS3_k127_7260819_1	1313172.YM304_21990	1.714e-110	370.0	COG1092@1|root,COG1092@2|Bacteria,2GXDD@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GDHHQS3_k127_7260819_2	1128421.JAGA01000001_gene2275	1.702e-97	329.0	COG1482@1|root,COG1482@2|Bacteria,2NR16@2323|unclassified Bacteria	2|Bacteria	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
GDHHQS3_k127_7260819_5	1121927.GOHSU_04_00230	9.959e-12	67.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4GF7U@85026|Gordoniaceae	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
GDHHQS3_k127_7260819_6	1336243.JAEA01000002_gene2859	4.838e-07	62.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,1JTQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM cyclic nucleotide-binding	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
GDHHQS3_k127_7260819_4	926569.ANT_16940	6.708e-54	205.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_7260819_0	926569.ANT_24910	2.636e-167	535.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_7320064_6	926569.ANT_29010	1.818e-127	411.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GDHHQS3_k127_7320064_19	926569.ANT_29020	6.211e-30	124.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GDHHQS3_k127_7320064_9	926569.ANT_02860	1.254e-88	305.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GDHHQS3_k127_7320064_0	926569.ANT_02850	3.059e-202	638.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GDHHQS3_k127_7320064_24	194867.ALBQ01000011_gene384	1.963e-05	47.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
GDHHQS3_k127_7320064_5	926569.ANT_07760	5.526e-128	416.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GDHHQS3_k127_7320064_7	926569.ANT_07770	6.861e-124	402.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GDHHQS3_k127_7320064_8	525904.Tter_0098	9.067e-99	336.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
GDHHQS3_k127_7320064_12	706587.Desti_2991	4.193e-69	246.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
GDHHQS3_k127_7320064_15	1123504.JQKD01000008_gene5341	3.68e-43	169.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS3_k127_7320064_22	765420.OSCT_2130	7.206e-19	89.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
GDHHQS3_k127_7320064_10	1231241.Mc24_02863	6.615e-72	252.0	COG0656@1|root,COG0656@2|Bacteria,2GCHS@200918|Thermotogae	200918|Thermotogae	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_7320064_14	313606.M23134_00054	3.023e-48	175.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,47QK8@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
GDHHQS3_k127_7320064_17	1128421.JAGA01000002_gene55	8.086e-36	146.0	COG2227@1|root,COG2227@2|Bacteria,2NRDG@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_7320064_11	926569.ANT_04520	2.463e-71	247.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GDHHQS3_k127_7320064_4	926569.ANT_04510	1.526e-128	414.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GDHHQS3_k127_7320064_2	926569.ANT_04500	3.623e-177	561.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GDHHQS3_k127_7320064_20	926569.ANT_04490	2.092e-26	109.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
GDHHQS3_k127_7320064_1	926569.ANT_04950	3.848e-185	586.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
GDHHQS3_k127_7320064_18	926569.ANT_28130	8.345e-34	135.0	COG2905@1|root,COG2905@2|Bacteria,2G9RX@200795|Chloroflexi	200795|Chloroflexi	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GDHHQS3_k127_7320064_16	1128421.JAGA01000002_gene1800	1.669e-38	149.0	COG2166@1|root,COG2166@2|Bacteria	2|Bacteria	S	iron-sulfur cluster assembly	sufE	-	-	ko:K02426,ko:K07125	-	-	-	-	ko00000	-	-	-	SufE
GDHHQS3_k127_7320064_3	926569.ANT_27870	2.303e-132	429.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_7320064_13	521097.Coch_1954	3.485e-66	231.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia,1ETI2@1016|Capnocytophaga	976|Bacteroidetes	C	RNase H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
GDHHQS3_k127_7320064_21	1249997.JHZW01000003_gene3414	8.256e-22	109.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1I0Y1@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
GDHHQS3_k127_7320064_25	653948.CCA19356	4.943e-05	55.0	COG0457@1|root,KOG0548@2759|Eukaryota	2759|Eukaryota	J	positive regulation of catalytic activity in other organism involved in symbiotic interaction	STI1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:1901363	-	ko:K09553	ko05020,map05020	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
GDHHQS3_k127_7332242_0	926569.ANT_29800	9.118e-126	407.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GDHHQS3_k127_7332242_3	1385514.N782_06400	1.88e-39	151.0	COG0494@1|root,COG0494@2|Bacteria,1VPHI@1239|Firmicutes,4HR9R@91061|Bacilli	91061|Bacilli	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_7332242_2	926550.CLDAP_05630	7.5e-46	177.0	COG0679@1|root,COG0679@2|Bacteria,2G90G@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
GDHHQS3_k127_7332242_1	926569.ANT_19940	5.176e-77	273.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GDHHQS3_k127_7332242_4	335543.Sfum_1427	1.418e-16	83.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,2MQMW@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GDHHQS3_k127_7344188_4	660470.Theba_0214	9.478e-16	77.0	COG1173@1|root,COG1173@2|Bacteria,2GCHA@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_7344188_6	1232683.ADIMK_1034	3.416e-05	54.0	COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,46A21@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
GDHHQS3_k127_7344188_0	926569.ANT_31100	2.522e-168	551.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GDHHQS3_k127_7344188_2	926569.ANT_01400	9.744e-153	490.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_7344188_1	926569.ANT_01410	1.844e-167	530.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GDHHQS3_k127_7344188_5	1121033.AUCF01000009_gene995	1.217e-12	79.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JQBN@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_7344188_3	926569.ANT_08650	3.745e-43	160.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GDHHQS3_k127_7375746_2	326427.Cagg_2719	1.49e-63	235.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,37659@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
GDHHQS3_k127_7375746_5	3702.AT3G20362.1	0.0008989	42.0	290WG@1|root,2R7RZ@2759|Eukaryota,3882J@33090|Viridiplantae,3GMGA@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7375746_1	926569.ANT_17030	8.798e-72	252.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yicL_1	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
GDHHQS3_k127_7375746_3	926569.ANT_04240	1.072e-55	206.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GDHHQS3_k127_7375746_0	926569.ANT_11940	7.385e-116	377.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GDHHQS3_k127_7375746_4	234267.Acid_7379	1.887e-24	115.0	2A08G@1|root,33ENC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7379413_0	368407.Memar_1159	7.946e-272	854.0	COG1002@1|root,arCOG02635@2157|Archaea,2Y89Z@28890|Euryarchaeota	28890|Euryarchaeota	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
GDHHQS3_k127_7379413_7	1170562.Cal6303_3244	7.803e-39	157.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria,1HM0P@1161|Nostocales	1117|Cyanobacteria	I	TIGRFAM lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GDHHQS3_k127_7379413_9	926569.ANT_15190	1.195e-32	132.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7379413_6	926569.ANT_15180	2.175e-41	156.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
GDHHQS3_k127_7379413_3	926569.ANT_03580	4.958e-102	355.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7379413_4	926569.ANT_04450	1.393e-64	228.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
GDHHQS3_k127_7379413_8	926569.ANT_04460	2.642e-35	141.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GDHHQS3_k127_7379413_2	926569.ANT_19820	1.288e-111	373.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GDHHQS3_k127_7379413_5	330214.NIDE4175	1.413e-51	194.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS3_k127_7379413_1	926569.ANT_28140	3.138e-211	661.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS3_k127_7379413_10	686340.Metal_3113	5.493e-25	121.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
GDHHQS3_k127_7379413_11	585503.HMPREF7545_0786	8.464e-13	74.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GDHHQS3_k127_7425461_15	530564.Psta_1177	4.432e-81	273.0	COG2040@1|root,COG2040@2|Bacteria,2J3GR@203682|Planctomycetes	203682|Planctomycetes	H	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
GDHHQS3_k127_7425461_5	1173025.GEI7407_3770	3.25e-115	395.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G26E@1117|Cyanobacteria,1H8TQ@1150|Oscillatoriales	1117|Cyanobacteria	PT	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
GDHHQS3_k127_7425461_9	926550.CLDAP_08640	1.188e-109	365.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
GDHHQS3_k127_7425461_6	326427.Cagg_2224	2.575e-114	380.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,375H2@32061|Chloroflexia	32061|Chloroflexia	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_7425461_17	1121422.AUMW01000006_gene744	1.742e-78	280.0	COG5598@1|root,COG5598@2|Bacteria,1V335@1239|Firmicutes,24GX0@186801|Clostridia,26435@186807|Peptococcaceae	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS3_k127_7425461_19	926560.KE387027_gene654	1.687e-61	234.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1WKH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GDHHQS3_k127_7425461_8	1047013.AQSP01000134_gene1338	7.03e-112	378.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GDHHQS3_k127_7425461_18	1089553.Tph_c27670	2.061e-62	222.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
GDHHQS3_k127_7425461_25	324602.Caur_2786	1.383e-32	136.0	COG1802@1|root,COG1802@2|Bacteria,2G993@200795|Chloroflexi,377MM@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS3_k127_7425461_24	1423321.AS29_02665	1.979e-40	163.0	COG3274@1|root,COG3274@2|Bacteria,1V0QX@1239|Firmicutes,4HFH3@91061|Bacilli,1ZHG6@1386|Bacillus	91061|Bacilli	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS3_k127_7425461_7	335541.Swol_1828	2.21e-112	388.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GDHHQS3_k127_7425461_12	926550.CLDAP_05930	1.577e-97	324.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
GDHHQS3_k127_7425461_0	439235.Dalk_2597	7.023e-213	685.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MIGI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM molybdopterin oxidoreductase	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_7425461_34	936375.HMPREF1152_0350	3.126e-05	50.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WCN9@538999|Clostridiales incertae sedis	186801|Clostridia	S	Uncharacterized protein family UPF0029	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
GDHHQS3_k127_7425461_11	1128421.JAGA01000003_gene3536	1.883e-98	338.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_7425461_13	1128421.JAGA01000003_gene3537	6.279e-89	302.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_7425461_3	926569.ANT_07930	2.246e-155	501.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_7425461_16	926569.ANT_07920	3.261e-80	276.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_7425461_21	926569.ANT_07910	1.2e-53	209.0	COG0845@1|root,COG0845@2|Bacteria,2G8US@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GDHHQS3_k127_7425461_32	506534.Rhein_0525	3.879e-15	78.0	COG2199@1|root,COG3706@2|Bacteria,1QXIS@1224|Proteobacteria,1T4KX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GDHHQS3_k127_7425461_20	1128421.JAGA01000003_gene3490	4.58e-55	199.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
GDHHQS3_k127_7425461_22	159087.Daro_3750	1.835e-53	208.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGZJ@28216|Betaproteobacteria,2KVQZ@206389|Rhodocyclales	206389|Rhodocyclales	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_4
GDHHQS3_k127_7425461_2	595460.RRSWK_00040	9.182e-159	515.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GDHHQS3_k127_7425461_4	1122604.JONR01000011_gene3689	1.849e-116	382.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GDHHQS3_k127_7425461_23	1183438.GKIL_4241	7.712e-53	195.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GDHHQS3_k127_7425461_14	926569.ANT_17320	2.39e-86	293.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7425461_31	926560.KE387023_gene1958	1.68e-17	89.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7425461_33	536232.CLM_1409	5.566e-09	66.0	COG4758@1|root,COG4758@2|Bacteria,1UITP@1239|Firmicutes,24NAQ@186801|Clostridia,36S7A@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
GDHHQS3_k127_7425461_27	42256.RradSPS_2809	1.985e-29	127.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7425461_29	926569.ANT_30850	1.07e-25	108.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
GDHHQS3_k127_7425461_28	926569.ANT_30840	1.928e-27	117.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Fer4_7,HTH_Crp_2,cNMP_binding
GDHHQS3_k127_7425461_26	383372.Rcas_0861	1.431e-31	130.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_7425461_1	926569.ANT_12080	2.031e-159	518.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
GDHHQS3_k127_7425461_10	926569.ANT_12100	1.675e-99	332.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
GDHHQS3_k127_7474168_1	635013.TherJR_2241	2.63e-134	438.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_7474168_17	1333856.L686_22695	0.0002533	49.0	COG1937@1|root,COG1937@2|Bacteria,1N1ES@1224|Proteobacteria,1SFI2@1236|Gammaproteobacteria,1Z3DC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K07807	-	-	-	-	ko00000	-	-	-	Trns_repr_metal
GDHHQS3_k127_7474168_6	670487.Ocepr_0484	9.993e-37	149.0	COG0785@1|root,COG0785@2|Bacteria,1WIZH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
GDHHQS3_k127_7474168_7	670487.Ocepr_0483	3.229e-29	123.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GDHHQS3_k127_7474168_14	526224.Bmur_2476	1.698e-07	57.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	2.7.7.77	ko:K03752,ko:K07213,ko:K08364	ko00790,ko01100,ko04978,map00790,map01100,map04978	-	R11581	-	ko00000,ko00001,ko01000,ko02000	1.A.72.1	-	-	HMA
GDHHQS3_k127_7474168_3	1382356.JQMP01000001_gene1199	4.357e-52	196.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_7474168_18	1448860.BBJO01000029_gene504	0.0005538	45.0	COG0701@1|root,arCOG02712@2157|Archaea,2XU5I@28890|Euryarchaeota,23T00@183963|Halobacteria	183963|Halobacteria	S	metal ion permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,YHS
GDHHQS3_k127_7474168_13	153948.NAL212_0227	1.239e-12	70.0	COG0500@1|root,COG2226@2|Bacteria,1PE85@1224|Proteobacteria,2W92M@28216|Betaproteobacteria,373FB@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_7474168_8	1117108.PAALTS15_28541	5.334e-28	115.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,26TVZ@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Ubie_methyltran
GDHHQS3_k127_7474168_16	1196323.ALKF01000187_gene5786	0.0001193	46.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,26TVZ@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Ubie_methyltran
GDHHQS3_k127_7474168_5	926569.ANT_20530	1.564e-41	163.0	COG0682@1|root,COG0682@2|Bacteria,2G8YW@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GDHHQS3_k127_7474168_4	926569.ANT_20540	1.042e-46	174.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi	200795|Chloroflexi	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GDHHQS3_k127_7474168_10	1449058.JQKT01000008_gene2429	3.414e-15	79.0	COG3339@1|root,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria,4FQ41@85023|Microbacteriaceae	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7474168_2	107635.AZUO01000005_gene4353	3.215e-94	313.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2TQZQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_7474168_9	1174528.JH992889_gene74	4.201e-17	83.0	2DVDD@1|root,32UZ7@2|Bacteria,1GAMG@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
GDHHQS3_k127_7474168_11	1410634.JHVD01000027_gene1655	1.531e-14	74.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
GDHHQS3_k127_7474168_15	661478.OP10G_1835	3.535e-05	51.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspC1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GDHHQS3_k127_7474168_12	1541065.JRFE01000058_gene5517	2.892e-14	75.0	COG0477@1|root,COG2814@2|Bacteria,1G3TG@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1
GDHHQS3_k127_7474168_0	1132855.KB913035_gene1532	8.817e-235	733.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2VI7H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
GDHHQS3_k127_75317_1	926569.ANT_03590	2.374e-181	592.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GDHHQS3_k127_75317_4	926569.ANT_01840	5.913e-126	411.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GDHHQS3_k127_75317_3	926569.ANT_05010	1.106e-133	434.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GDHHQS3_k127_75317_0	926569.ANT_12840	5.231e-225	721.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GDHHQS3_k127_75317_7	926569.ANT_12670	2.111e-60	212.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GDHHQS3_k127_75317_5	926569.ANT_12660	6.539e-101	340.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GDHHQS3_k127_75317_2	926569.ANT_12630	1.487e-142	458.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GDHHQS3_k127_75317_6	926569.ANT_12620	2.206e-84	288.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GDHHQS3_k127_75317_9	767817.Desgi_2099	2.288e-08	64.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,24QQ6@186801|Clostridia,262ZF@186807|Peptococcaceae	186801|Clostridia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GDHHQS3_k127_75317_8	443143.GM18_0493	2.777e-09	67.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Chromate	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GDHHQS3_k127_7712113_0	324602.Caur_2788	7.123e-265	824.0	COG3333@1|root,COG3333@2|Bacteria,2G7QR@200795|Chloroflexi	200795|Chloroflexi	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
GDHHQS3_k127_7712113_3	324602.Caur_2789	5.05e-54	194.0	2DMZ7@1|root,32UI9@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
GDHHQS3_k127_7712113_1	324602.Caur_2790	6.329e-153	488.0	COG3181@1|root,COG3181@2|Bacteria,2G8UI@200795|Chloroflexi	200795|Chloroflexi	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
GDHHQS3_k127_7712113_2	1235279.C772_01112	6.539e-76	267.0	COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,4HCDV@91061|Bacilli,26FM8@186818|Planococcaceae	91061|Bacilli	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
GDHHQS3_k127_7712113_6	344747.PM8797T_05440	6.978e-06	48.0	COG4422@1|root,COG4422@2|Bacteria,2IY1I@203682|Planctomycetes	203682|Planctomycetes	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GDHHQS3_k127_7712113_4	314230.DSM3645_24370	1.033e-44	170.0	COG2197@1|root,COG2197@2|Bacteria,2IZHB@203682|Planctomycetes	203682|Planctomycetes	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_7712113_5	42256.RradSPS_2102	3.627e-32	144.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
GDHHQS3_k127_7782175_18	1246484.D479_08286	0.0002839	44.0	COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,3NE2J@45667|Halobacillus	91061|Bacilli	S	Putative adhesin	yvlB	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_7782175_13	926569.ANT_10390	4.325e-21	105.0	COG3595@1|root,COG3595@2|Bacteria,2G7DM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GDHHQS3_k127_7782175_10	926550.CLDAP_09770	6.512e-33	132.0	COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
GDHHQS3_k127_7782175_6	1157637.KB892101_gene2502	1.098e-51	199.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GDHHQS3_k127_7782175_2	886293.Sinac_6174	1.194e-89	306.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GDHHQS3_k127_7782175_4	926569.ANT_18940	2.777e-61	221.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi	200795|Chloroflexi	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GDHHQS3_k127_7782175_14	1139996.OMQ_01137	4.131e-20	103.0	COG2304@1|root,COG2304@2|Bacteria,1VAM7@1239|Firmicutes,4HRQG@91061|Bacilli	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GDHHQS3_k127_7782175_11	886293.Sinac_1819	7.284e-24	111.0	COG1716@1|root,COG1716@2|Bacteria,2J1IJ@203682|Planctomycetes	203682|Planctomycetes	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
GDHHQS3_k127_7782175_12	530564.Psta_4147	7.101e-23	107.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
GDHHQS3_k127_7782175_16	530564.Psta_4149	2.52e-11	67.0	2EFHE@1|root,3399Z@2|Bacteria,2J10E@203682|Planctomycetes	203682|Planctomycetes	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
GDHHQS3_k127_7782175_9	326424.FRAAL0854	8.95e-37	151.0	COG5078@1|root,COG5078@2|Bacteria	2|Bacteria	O	protein modification by small protein conjugation	-	-	-	-	-	-	-	-	-	-	-	-	ThiF,UQ_con,Yop-YscD_cpl
GDHHQS3_k127_7782175_0	886293.Sinac_1731	2.702e-103	357.0	COG0476@1|root,COG0476@2|Bacteria,2IY9K@203682|Planctomycetes	203682|Planctomycetes	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
GDHHQS3_k127_7782175_17	292.DM42_5713	2.04e-10	74.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VRX4@28216|Betaproteobacteria,1KCT8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GDHHQS3_k127_7782175_8	926569.ANT_18950	3.74e-45	166.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GDHHQS3_k127_7782175_7	926569.ANT_18960	2.083e-46	173.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GDHHQS3_k127_7782175_1	926569.ANT_18970	1.112e-97	324.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GDHHQS3_k127_7782175_3	926569.ANT_18980	5.785e-70	239.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GDHHQS3_k127_7782175_5	926569.ANT_18990	2.427e-58	203.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
GDHHQS3_k127_7859157_1	279714.FuraDRAFT_2307	4.242e-167	535.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,2KPWM@206351|Neisseriales	206351|Neisseriales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GDHHQS3_k127_7859157_2	309799.DICTH_0008	4.996e-112	372.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Cellulase
GDHHQS3_k127_7859157_0	880073.Calab_0341	4.244e-249	777.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GDHHQS3_k127_7859157_4	266117.Rxyl_2783	2.423e-46	194.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
GDHHQS3_k127_7859157_3	926569.ANT_03450	1.413e-80	306.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS3_k127_7860928_11	926569.ANT_13370	1.468e-24	103.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GDHHQS3_k127_7860928_8	926569.ANT_13360	1.018e-67	239.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GDHHQS3_k127_7860928_1	926569.ANT_13340	7.42e-255	814.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GDHHQS3_k127_7860928_5	1120980.JQKH01000109_gene972	4.509e-128	417.0	COG0616@1|root,COG0616@2|Bacteria,1Q17C@1224|Proteobacteria,2W689@28216|Betaproteobacteria	28216|Betaproteobacteria	OU	signal peptide processing	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7860928_0	329726.AM1_2452	2.576e-255	837.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GDHHQS3_k127_7860928_4	247490.KSU1_C0108	4.754e-163	524.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GDHHQS3_k127_7860928_7	1227352.C173_27310	1.115e-75	264.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_7860928_6	41431.PCC8801_2345	2.183e-90	307.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1GHX6@1117|Cyanobacteria,3KJ06@43988|Cyanothece	1117|Cyanobacteria	H	Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1
GDHHQS3_k127_7860928_2	357808.RoseRS_2594	6.455e-240	748.0	COG1231@1|root,COG1231@2|Bacteria,2G942@200795|Chloroflexi	200795|Chloroflexi	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GDHHQS3_k127_7860928_10	1192034.CAP_7281	1.374e-50	194.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,432YH@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyl hydrolases family 25	yegX	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
GDHHQS3_k127_7860928_3	926550.CLDAP_18930	1.976e-175	560.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GDHHQS3_k127_7860928_9	118166.JH976537_gene4051	7.291e-65	226.0	COG4894@1|root,COG4894@2|Bacteria,1GEPD@1117|Cyanobacteria	1117|Cyanobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
GDHHQS3_k127_7862288_2	926569.ANT_31620	2.497e-13	70.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GDHHQS3_k127_7862288_1	926569.ANT_31610	2.344e-70	255.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K16694	-	-	-	-	ko00000,ko02000	2.A.66.2.6	-	-	Polysacc_synt_3
GDHHQS3_k127_7862288_0	926569.ANT_00620	6.894e-93	319.0	COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GDHHQS3_k127_7866382_2	926550.CLDAP_24920	3.018e-120	395.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GDHHQS3_k127_7866382_12	1196029.ALIM01000034_gene1751	6.82e-20	94.0	2DF5F@1|root,330HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7866382_6	926569.ANT_04330	1.567e-58	211.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GDHHQS3_k127_7866382_10	926569.ANT_04340	7.389e-24	109.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	mec	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GDHHQS3_k127_7866382_1	926569.ANT_04370	0.0	1068.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GDHHQS3_k127_7866382_0	926569.ANT_25700	0.0	1196.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GDHHQS3_k127_7866382_4	926569.ANT_25690	1.882e-76	270.0	COG3287@1|root,COG3287@2|Bacteria,2G7G0@200795|Chloroflexi	200795|Chloroflexi	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GDHHQS3_k127_7866382_13	236814.IX39_05910	0.0006075	50.0	2DBYB@1|root,2ZBUC@2|Bacteria,4NRE9@976|Bacteroidetes,1I3UH@117743|Flavobacteriia,3ZR1V@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7866382_9	926569.ANT_12680	6.517e-41	156.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GDHHQS3_k127_7866382_3	383372.Rcas_4360	2.182e-110	365.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
GDHHQS3_k127_7866382_5	357808.RoseRS_0170	3.331e-75	263.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
GDHHQS3_k127_7866382_11	357808.RoseRS_0169	4.549e-21	95.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
GDHHQS3_k127_7901242_0	926569.ANT_06370	4.629e-99	332.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_7901242_2	1408444.JHYC01000009_gene1668	6.725e-27	127.0	COG1807@1|root,COG1807@2|Bacteria,1QC7N@1224|Proteobacteria,1T7WU@1236|Gammaproteobacteria,1JFYQ@118969|Legionellales	118969|Legionellales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_7901242_1	926569.ANT_06360	1.73e-67	232.0	COG2089@1|root,COG2089@2|Bacteria,2G8PB@200795|Chloroflexi	200795|Chloroflexi	M	SAF	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
GDHHQS3_k127_8017011_3	926569.ANT_22630	2.968e-84	291.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GDHHQS3_k127_8017011_0	926569.ANT_22640	1.234e-116	385.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GDHHQS3_k127_8017011_1	926569.ANT_22650	1.262e-94	327.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_8017011_2	926569.ANT_22660	3.899e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_8017011_5	1304880.JAGB01000002_gene1995	1.216e-44	166.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GDHHQS3_k127_8017011_4	926569.ANT_27450	4.623e-45	169.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
GDHHQS3_k127_8019669_21	1121904.ARBP01000006_gene3740	3.75e-34	136.0	COG0457@1|root,COG0457@2|Bacteria,4PBAK@976|Bacteroidetes,47VJ2@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8019669_28	1521187.JPIM01000022_gene618	8.175e-08	63.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GDHHQS3_k127_8019669_19	1242864.D187_001151	8.127e-54	201.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GDHHQS3_k127_8019669_8	926569.ANT_08060	1.142e-134	437.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GDHHQS3_k127_8019669_9	324602.Caur_1110	6.487e-130	433.0	COG1472@1|root,COG1472@2|Bacteria,2G8JU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GDHHQS3_k127_8019669_6	926569.ANT_08070	7.851e-147	469.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_8019669_4	926569.ANT_08080	6.783e-183	579.0	COG1175@1|root,COG1175@2|Bacteria,2G6TJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_8019669_1	926569.ANT_08090	2.487e-239	745.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_8019669_12	926569.ANT_08100	3.072e-121	395.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GDHHQS3_k127_8019669_3	926569.ANT_08110	2.667e-210	662.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GDHHQS3_k127_8019669_5	926569.ANT_08120	3.953e-148	478.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi	200795|Chloroflexi	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
GDHHQS3_k127_8019669_26	251229.Chro_3665	1.395e-15	86.0	2DNDG@1|root,32WY9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8019669_17	926550.CLDAP_26730	2.426e-80	273.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GDHHQS3_k127_8019669_23	331678.Cphamn1_0275	2.19e-24	110.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_8019669_22	646529.Desaci_0681	5.868e-25	111.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GDHHQS3_k127_8019669_7	357808.RoseRS_4512	1.655e-137	445.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
GDHHQS3_k127_8019669_10	357808.RoseRS_4511	3.976e-129	417.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
GDHHQS3_k127_8019669_2	357808.RoseRS_4510	1.542e-222	697.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
GDHHQS3_k127_8019669_11	1121380.JNIW01000091_gene3310	8.841e-128	417.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GDHHQS3_k127_8019669_15	479434.Sthe_3148	1.314e-98	335.0	COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi	200795|Chloroflexi	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8019669_24	1150621.SMUL_1017	8.151e-21	95.0	COG0640@1|root,COG0640@2|Bacteria,1N8M7@1224|Proteobacteria,42U4R@68525|delta/epsilon subdivisions,2YPYH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	arsR family	smtB	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GDHHQS3_k127_8019669_0	926550.CLDAP_21170	1.277e-269	846.0	COG2217@1|root,COG2217@2|Bacteria,2G65K@200795|Chloroflexi	200795|Chloroflexi	P	Heavy-metal-associated domain	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GDHHQS3_k127_8019669_13	243233.MCA1900	7.726e-107	355.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XF2R@135618|Methylococcales	135618|Methylococcales	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GDHHQS3_k127_8019669_16	1536769.P40081_36490	4.799e-96	325.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HBXP@91061|Bacilli,26VNN@186822|Paenibacillaceae	91061|Bacilli	V	Bacitracin ABC transporter, ATP-binding protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8019669_18	871963.Desdi_1444	8.614e-70	246.0	COG1277@1|root,COG1277@2|Bacteria,1V787@1239|Firmicutes,25DDT@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
GDHHQS3_k127_8019669_25	1267534.KB906756_gene149	9.652e-20	93.0	2ESJ3@1|root,33K3T@2|Bacteria,3Y8Y6@57723|Acidobacteria,2JNTF@204432|Acidobacteriia	204432|Acidobacteriia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GDHHQS3_k127_8019669_20	1541065.JRFE01000026_gene2122	9.648e-42	157.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
GDHHQS3_k127_8019669_14	485913.Krac_2841	1.483e-101	345.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GDHHQS3_k127_8019669_29	1499967.BAYZ01000161_gene390	2.72e-05	48.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2NNXD@2323|unclassified Bacteria	2|Bacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,HSDR_N,N6_Mtase,TaqI_C
GDHHQS3_k127_8031881_14	1459636.NTE_02190	3.408e-40	152.0	COG5649@1|root,2N58B@2157|Archaea	2157|Archaea	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GDHHQS3_k127_8031881_12	405948.SACE_0358	1.603e-68	236.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria,4E53M@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GDHHQS3_k127_8031881_10	485913.Krac_5673	5.389e-91	302.0	COG0262@1|root,COG0262@2|Bacteria,2G8UG@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_8031881_11	32057.KB217480_gene8206	7.957e-72	248.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GDHHQS3_k127_8031881_13	195253.Syn6312_0837	5.676e-62	218.0	COG0262@1|root,COG0262@2|Bacteria,1GEAQ@1117|Cyanobacteria	1117|Cyanobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GDHHQS3_k127_8031881_7	485913.Krac_9623	3.568e-123	403.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GDHHQS3_k127_8031881_0	926569.ANT_12440	4.118e-197	624.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GDHHQS3_k127_8031881_2	926569.ANT_12430	3.115e-170	546.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi	200795|Chloroflexi	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GDHHQS3_k127_8031881_15	926569.ANT_12420	1.064e-16	80.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
GDHHQS3_k127_8031881_6	926569.ANT_12410	3.817e-130	421.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi	200795|Chloroflexi	HJ	Belongs to the RimK family	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
GDHHQS3_k127_8031881_3	926569.ANT_12400	3.322e-153	491.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GDHHQS3_k127_8031881_9	383372.Rcas_3466	4.301e-95	320.0	COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,375DI@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_8031881_5	316274.Haur_3309	1.344e-138	451.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi,375D1@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GDHHQS3_k127_8031881_8	926569.ANT_12370	1.352e-107	359.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
GDHHQS3_k127_8031881_4	203119.Cthe_1845	6.823e-141	453.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,HTS
GDHHQS3_k127_8031881_1	696281.Desru_1829	1.961e-173	555.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,26060@186807|Peptococcaceae	186801|Clostridia	E	PFAM Cys Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GDHHQS3_k127_8034272_13	926569.ANT_18930	1.693e-07	59.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
GDHHQS3_k127_8034272_8	1379270.AUXF01000002_gene1135	1.56e-29	124.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_8034272_5	246197.MXAN_6602	5.974e-47	175.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
GDHHQS3_k127_8034272_6	1128421.JAGA01000002_gene1694	6.027e-40	160.0	COG2176@1|root,COG2378@1|root,COG2176@2|Bacteria,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	dnaQ	-	2.7.7.7	ko:K02342,ko:K03763,ko:K13573	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03051,ko03400	-	-	-	GIY-YIG,RNase_T,VRR_NUC,WYL
GDHHQS3_k127_8034272_10	640513.Entas_2303	9.002e-20	101.0	COG1835@1|root,COG1835@2|Bacteria,1NF1K@1224|Proteobacteria,1SM5V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GDHHQS3_k127_8034272_9	926569.ANT_11780	1.71e-21	105.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8034272_4	861299.J421_0746	6.186e-51	185.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8034272_7	313596.RB2501_12022	1.025e-37	155.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GDHHQS3_k127_8034272_2	357808.RoseRS_4538	2.694e-165	527.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_8034272_14	641147.HMPREF9021_00507	0.0002378	45.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KPYD@206351|Neisseriales	206351|Neisseriales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_8034272_11	926569.ANT_10660	1.637e-16	82.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_8034272_0	1122138.AQUZ01000019_gene8174	0.0	1669.0	COG0737@1|root,COG1524@1|root,COG3379@1|root,COG0737@2|Bacteria,COG1524@2|Bacteria,COG3379@2|Bacteria,2HFJ5@201174|Actinobacteria,4DVDK@85009|Propionibacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C
GDHHQS3_k127_8034272_1	926569.ANT_10660	0.0	1192.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GDHHQS3_k127_8034272_15	1278308.KB907079_gene2127	0.0007745	42.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FMW7@85023|Microbacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GDHHQS3_k127_8034272_3	56110.Oscil6304_3204	1.199e-51	200.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GDHHQS3_k127_8034272_12	399739.Pmen_0072	2.723e-08	62.0	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GDHHQS3_k127_8038024_9	926569.ANT_27540	8.631e-09	57.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GDHHQS3_k127_8038024_3	926569.ANT_27550	1.647e-74	257.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
GDHHQS3_k127_8038024_4	926569.ANT_04570	1.59e-62	224.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
GDHHQS3_k127_8038024_0	357808.RoseRS_0214	7.217e-254	794.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GDHHQS3_k127_8038024_6	246196.MSMEI_1937	8.536e-30	127.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,239B9@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GDHHQS3_k127_8038024_7	324602.Caur_2619	2.924e-26	115.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GDHHQS3_k127_8038024_2	321332.CYB_0528	3.983e-79	286.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria,1GYSX@1129|Synechococcus	1117|Cyanobacteria	P	GPH family sugar transporter	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
GDHHQS3_k127_8038024_1	926569.ANT_14560	1.305e-84	297.0	COG0790@1|root,COG3359@1|root,COG0790@2|Bacteria,COG3359@2|Bacteria,2G6TK@200795|Chloroflexi	200795|Chloroflexi	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GDHHQS3_k127_8038024_10	1244869.H261_14805	1.03e-05	53.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,2UH20@28211|Alphaproteobacteria,2JTY1@204441|Rhodospirillales	204441|Rhodospirillales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GDHHQS3_k127_8038024_5	1246995.AFR_12630	1.267e-60	228.0	COG4097@1|root,COG4097@2|Bacteria,2IJJH@201174|Actinobacteria	201174|Actinobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
GDHHQS3_k127_8038024_11	1220534.B655_1281	0.0003132	49.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y4H8@28890|Euryarchaeota	28890|Euryarchaeota	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS3_k127_8038024_8	926569.ANT_29070	8.488e-23	103.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_8038024_12	1120934.KB894404_gene612	0.0009159	48.0	COG2215@1|root,COG2215@2|Bacteria,2H0S3@201174|Actinobacteria,4E8I1@85010|Pseudonocardiales	201174|Actinobacteria	S	High-affinity nickel-transport protein	-	-	-	-	-	-	-	-	-	-	-	-	NicO
GDHHQS3_k127_8046699_17	926569.ANT_06620	7.588e-07	51.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_8046699_11	926569.ANT_06690	5.098e-47	178.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
GDHHQS3_k127_8046699_5	926569.ANT_06700	7.209e-129	421.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi	200795|Chloroflexi	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
GDHHQS3_k127_8046699_3	926569.ANT_06710	2.281e-156	511.0	COG1178@1|root,COG1178@2|Bacteria,2G63A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
GDHHQS3_k127_8046699_7	926569.ANT_23590	1.883e-99	335.0	COG3842@1|root,COG3842@2|Bacteria,2G62Z@200795|Chloroflexi	200795|Chloroflexi	P	TOBE domain	-	-	3.6.3.31	ko:K02062,ko:K11072	ko02010,map02010	M00191,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_8046699_12	926569.ANT_23580	3.749e-29	121.0	COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi	200795|Chloroflexi	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GDHHQS3_k127_8046699_10	926569.ANT_23560	6.549e-51	186.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GDHHQS3_k127_8046699_8	926569.ANT_23520	8.982e-56	205.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS3_k127_8046699_6	635013.TherJR_2349	1.897e-125	412.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GDHHQS3_k127_8046699_4	926569.ANT_29410	1.157e-135	441.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS3_k127_8046699_2	926550.CLDAP_40590	4.593e-186	589.0	COG0535@1|root,COG2002@1|root,COG0535@2|Bacteria,COG2002@2|Bacteria,2G75Y@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
GDHHQS3_k127_8046699_13	326427.Cagg_1165	2.057e-24	106.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi,377DC@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GDHHQS3_k127_8046699_0	326427.Cagg_1166	0.0	1008.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,376PZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_8046699_1	926569.ANT_30270	2.168e-277	869.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_8046699_9	1519464.HY22_02245	6.038e-52	187.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GDHHQS3_k127_8046699_15	237368.SCABRO_03339	6.527e-14	74.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GDHHQS3_k127_8046699_14	237368.SCABRO_03340	2.65e-21	97.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8085763_0	861299.J421_5885	2.315e-99	348.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1ZUID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8085763_6	926569.ANT_02810	1.26e-05	52.0	2ESUF@1|root,33KCV@2|Bacteria,2G9MJ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8085763_4	690585.JNNU01000006_gene1293	4.337e-34	151.0	COG0784@1|root,COG3920@1|root,COG4585@1|root,COG5000@1|root,COG0784@2|Bacteria,COG3920@2|Bacteria,COG4585@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,2TZ2H@28211|Alphaproteobacteria,4BNY6@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_4,Response_reg
GDHHQS3_k127_8085763_1	63737.Npun_F3675	1.844e-96	343.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,1G2QC@1117|Cyanobacteria,1HR6C@1161|Nostocales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4
GDHHQS3_k127_8085763_3	338966.Ppro_3011	2.729e-58	205.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,43CDX@68525|delta/epsilon subdivisions,2X7PU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GDHHQS3_k127_8085763_5	1209989.TepiRe1_2733	1.841e-30	139.0	COG3437@1|root,COG3437@2|Bacteria,1V59B@1239|Firmicutes,24HMQ@186801|Clostridia	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PAS_8,PocR,Response_reg
GDHHQS3_k127_8085763_2	1322246.BN4_12484	1.774e-60	233.0	COG4191@1|root,COG4585@1|root,COG5000@1|root,COG4191@2|Bacteria,COG4585@2|Bacteria,COG5000@2|Bacteria,1RB4Z@1224|Proteobacteria,42SHV@68525|delta/epsilon subdivisions,2X7QP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9
GDHHQS3_k127_8110834_8	509191.AEDB02000094_gene4352	2.38e-43	162.0	COG4271@1|root,COG4271@2|Bacteria	2|Bacteria	-	-	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FRG,Pkinase,TIR-like
GDHHQS3_k127_8110834_1	926569.ANT_19790	8.97e-208	670.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GDHHQS3_k127_8110834_3	670487.Ocepr_1481	4.672e-104	348.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8110834_5	643473.KB235930_gene1765	2.502e-56	213.0	COG5542@1|root,COG5542@2|Bacteria,1GDW7@1117|Cyanobacteria,1HIN0@1161|Nostocales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8110834_2	102129.Lepto7375DRAFT_6394	3.419e-153	502.0	COG5421@1|root,COG5421@2|Bacteria,1G4EU@1117|Cyanobacteria,1HA9E@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GDHHQS3_k127_8110834_0	926569.ANT_19800	3.169e-208	668.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8110834_7	926550.CLDAP_13410	3.602e-44	169.0	COG0412@1|root,COG0412@2|Bacteria,2G6NY@200795|Chloroflexi	200795|Chloroflexi	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_8110834_12	768679.TTX_2012	4.233e-05	56.0	COG0616@1|root,arCOG01311@2157|Archaea	2157|Archaea	OU	signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS3_k127_8110834_9	926550.CLDAP_09610	1.984e-36	150.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GDHHQS3_k127_8110834_11	926569.ANT_25120	3.729e-30	126.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GDHHQS3_k127_8110834_10	926569.ANT_25130	4.278e-35	135.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GDHHQS3_k127_8110834_6	926569.ANT_25140	3.639e-47	175.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GDHHQS3_k127_8110834_4	926569.ANT_14160	3.449e-84	283.0	COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi	200795|Chloroflexi	F	PFAM thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GDHHQS3_k127_8110834_13	926569.ANT_14170	0.0003718	44.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_8129659_9	357808.RoseRS_3512	2.02e-11	75.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8129659_8	1121934.AUDX01000006_gene2021	1.561e-11	69.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8129659_0	1170562.Cal6303_2739	6.352e-136	457.0	COG0520@1|root,COG1672@1|root,COG2319@1|root,COG0520@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
GDHHQS3_k127_8129659_6	357808.RoseRS_3512	1.563e-14	85.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8129659_1	383372.Rcas_0955	2.573e-49	177.0	arCOG07672@1|root,32Z5Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GDHHQS3_k127_8129659_2	383372.Rcas_0956	3.984e-33	129.0	2DZQY@1|root,32VGM@2|Bacteria,2G8U6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8129659_7	767817.Desgi_4543	1.128e-12	70.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24P7S@186801|Clostridia,26328@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GDHHQS3_k127_8129659_4	383372.Rcas_4165	4.612e-15	87.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8129659_5	307480.IW16_12520	8.843e-15	80.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes,1I4GX@117743|Flavobacteriia,3ZSES@59732|Chryseobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
GDHHQS3_k127_8129659_3	1121930.AQXG01000007_gene409	7.031e-23	101.0	COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Transcriptional regulator PadR N-terminal-like	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GDHHQS3_k127_8135613_4	118173.KB235910_gene4798	3.301e-22	98.0	2C4F3@1|root,32D38@2|Bacteria,1G6WA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8135613_3	489825.LYNGBM3L_67230	9.682e-31	126.0	2CA6H@1|root,32RQP@2|Bacteria,1G86X@1117|Cyanobacteria,1HDCD@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_8135613_2	485913.Krac_2535	3.773e-32	132.0	COG0778@1|root,COG0778@2|Bacteria,2G79R@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GDHHQS3_k127_8135613_0	926569.ANT_17090	4.594e-108	376.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
GDHHQS3_k127_8135613_5	926569.ANT_09970	3.606e-22	102.0	COG0394@1|root,COG0394@2|Bacteria,2G7C2@200795|Chloroflexi	200795|Chloroflexi	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GDHHQS3_k127_8135613_1	926569.ANT_19500	1.099e-37	145.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	rfaH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
GDHHQS3_k127_8166069_3	497321.C664_17340	7.534e-61	211.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,2VQZE@28216|Betaproteobacteria,2KW2S@206389|Rhodocyclales	206389|Rhodocyclales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GDHHQS3_k127_8166069_2	926569.ANT_15950	8.107e-64	228.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GDHHQS3_k127_8166069_0	926569.ANT_16290	5.472e-304	944.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
GDHHQS3_k127_8169_1	926550.CLDAP_21020	1.696e-63	222.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_8169_0	1499967.BAYZ01000038_gene2269	6.356e-176	565.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,PAS_3,PAS_9
GDHHQS3_k127_8169_2	1121877.JQKF01000002_gene1609	1.007e-39	158.0	COG4932@1|root,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria	201174|Actinobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
GDHHQS3_k127_8169_4	73044.JNXP01000026_gene2275	4.367e-11	72.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GDHHQS3_k127_8182896_4	1452536.JARE01000066_gene1198	1.326e-60	214.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
GDHHQS3_k127_8182896_2	1120983.KB894571_gene2471	7.195e-74	256.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GDHHQS3_k127_8182896_6	1202768.JROF01000013_gene891	1.992e-15	87.0	COG0697@1|root,arCOG00272@2157|Archaea,2XUHA@28890|Euryarchaeota,23UY1@183963|Halobacteria	183963|Halobacteria	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_8182896_3	66874.JOFS01000001_gene1056	3.12e-64	231.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
GDHHQS3_k127_8182896_7	70601.3256943	6.533e-08	59.0	COG1917@1|root,arCOG02994@2157|Archaea,2XZZJ@28890|Euryarchaeota,2448V@183968|Thermococci	183968|Thermococci	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GDHHQS3_k127_8182896_0	1410620.SHLA_38c000530	1.67e-162	523.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,4B9XR@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8182896_1	351607.Acel_0890	3.311e-114	378.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4EU2M@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Hydrolase_4
GDHHQS3_k127_8182896_5	1123023.JIAI01000004_gene7873	7.356e-36	145.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_8185509_1	1499967.BAYZ01000089_gene5038	3.207e-110	370.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GDHHQS3_k127_8185509_0	383372.Rcas_2912	5.946e-136	439.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GDHHQS3_k127_8185509_4	383372.Rcas_2914	1.398e-19	99.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
GDHHQS3_k127_8185509_3	926569.ANT_17270	2.004e-32	132.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
GDHHQS3_k127_8185509_2	926569.ANT_17290	8.746e-33	130.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GDHHQS3_k127_8188241_5	926569.ANT_21770	2.877e-50	187.0	COG1192@1|root,COG1192@2|Bacteria,2G8YP@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GDHHQS3_k127_8188241_0	926569.ANT_28990	1.659e-174	556.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GDHHQS3_k127_8188241_4	926569.ANT_00350	6.065e-54	198.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8188241_8	926569.ANT_00360	3.192e-32	133.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8188241_3	926569.ANT_00370	2.958e-57	228.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GDHHQS3_k127_8188241_7	926569.ANT_00380	9.132e-39	154.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8188241_1	926569.ANT_00390	1.075e-145	481.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
GDHHQS3_k127_8188241_2	926569.ANT_00400	4.063e-89	305.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8188241_6	1123057.P872_21170	9.64e-46	171.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	tauX	-	-	ko:K07255,ko:K21700	ko00430,map00430	-	R01685	RC00062	ko00000,ko00001,ko01000	-	-	-	SnoaL_2
GDHHQS3_k127_8188871_0	926569.ANT_25540	1.376e-116	383.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GDHHQS3_k127_8188871_2	1449357.JQLK01000001_gene2227	2.078e-34	137.0	COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GDHHQS3_k127_8188871_1	926569.ANT_16940	9.053e-61	233.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_8237578_4	383372.Rcas_1889	2.372e-39	149.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GDHHQS3_k127_8237578_5	1111479.AXAR01000008_gene2391	2.35e-32	132.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4IQF7@91061|Bacilli,279Q5@186823|Alicyclobacillaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
GDHHQS3_k127_8237578_6	926569.ANT_20480	2.363e-31	128.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8237578_8	926569.ANT_20470	6.605e-22	99.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GDHHQS3_k127_8237578_7	765420.OSCT_0622	2.761e-27	122.0	COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi,377H0@32061|Chloroflexia	32061|Chloroflexia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GDHHQS3_k127_8237578_2	709986.Deima_1278	1.799e-52	192.0	COG1272@1|root,COG1272@2|Bacteria,1WK6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
GDHHQS3_k127_8237578_0	1521187.JPIM01000063_gene2480	2.166e-199	642.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GDHHQS3_k127_8237578_1	1033810.HLPCO_000691	9.84e-83	291.0	COG4188@1|root,COG4188@2|Bacteria,2NRT2@2323|unclassified Bacteria	2|Bacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,PAF-AH_p_II
GDHHQS3_k127_8237578_3	485913.Krac_9331	6.521e-49	179.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GDHHQS3_k127_8238054_12	247633.GP2143_04935	5.157e-49	179.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,1J602@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GDHHQS3_k127_8238054_16	272558.10176004	3.601e-30	134.0	COG0457@1|root,COG0457@2|Bacteria,1U9ZE@1239|Firmicutes,4IK7A@91061|Bacilli,1ZFKG@1386|Bacillus	91061|Bacilli	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
GDHHQS3_k127_8238054_3	1385935.N836_16145	2.161e-73	274.0	COG2319@1|root,COG3267@1|root,COG4409@1|root,COG5295@1|root,COG2319@2|Bacteria,COG3267@2|Bacteria,COG4409@2|Bacteria,COG5295@2|Bacteria,1GQM4@1117|Cyanobacteria,1HI3C@1150|Oscillatoriales	1117|Cyanobacteria	UW	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8238054_15	706587.Desti_0450	6.74e-35	145.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GDHHQS3_k127_8238054_18	891968.Anamo_0735	3.576e-24	106.0	COG4392@1|root,COG4392@2|Bacteria	2|Bacteria	E	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
GDHHQS3_k127_8238054_6	891968.Anamo_0736	1.947e-70	245.0	COG1296@1|root,COG1296@2|Bacteria,3TBT2@508458|Synergistetes	508458|Synergistetes	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
GDHHQS3_k127_8238054_4	485913.Krac_5249	2.191e-73	253.0	COG2197@1|root,COG2197@2|Bacteria,2G8M7@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_8238054_9	1280390.CBQR020000036_gene782	2.003e-57	214.0	COG4585@1|root,COG4585@2|Bacteria,1UYVE@1239|Firmicutes,4HGNS@91061|Bacilli,26U39@186822|Paenibacillaceae	91061|Bacilli	T	signal transduction histidine kinase	ydfH	-	2.7.13.3	ko:K11623	ko02020,map02020	M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GDHHQS3_k127_8238054_2	926569.ANT_08150	1.953e-102	342.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GDHHQS3_k127_8238054_23	930171.Asphe3_21100	6.929e-16	90.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
GDHHQS3_k127_8238054_14	926569.ANT_08170	3.4e-37	156.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GDHHQS3_k127_8238054_19	485913.Krac_3124	1.235e-21	99.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8238054_10	926550.CLDAP_14450	1.584e-54	199.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GDHHQS3_k127_8238054_8	1128421.JAGA01000002_gene1308	4.542e-62	220.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_8238054_11	525904.Tter_0301	4.494e-49	196.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
GDHHQS3_k127_8238054_13	1122218.KB893654_gene1893	5.569e-41	162.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,1JVP8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GDHHQS3_k127_8238054_17	644966.Tmar_1592	2.499e-26	112.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069,Lactamase_B,Rhodanese
GDHHQS3_k127_8238054_0	868595.Desca_2404	2.535e-209	659.0	COG0348@1|root,COG0348@2|Bacteria,1U9JQ@1239|Firmicutes,24ADI@186801|Clostridia,26078@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
GDHHQS3_k127_8238054_22	869210.Marky_1036	1.817e-16	79.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_8238054_24	566466.NOR53_1860	2.296e-07	59.0	COG0607@1|root,COG0607@2|Bacteria,1NGN9@1224|Proteobacteria,1SIKU@1236|Gammaproteobacteria,1J77D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395,Rhodanese
GDHHQS3_k127_8238054_21	869210.Marky_1036	3.556e-17	81.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
GDHHQS3_k127_8238054_5	580332.Slit_2500	2.604e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GDHHQS3_k127_8238054_1	580332.Slit_2499	6.983e-118	395.0	COG4585@1|root,COG4585@2|Bacteria,1MZY3@1224|Proteobacteria,2VZ3M@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GDHHQS3_k127_8238054_7	1123355.JHYO01000017_gene3613	2.599e-69	255.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GDHHQS3_k127_8238054_26	1463861.JNXE01000021_gene4286	1.933e-06	52.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GDHHQS3_k127_8238054_20	702113.PP1Y_AT23296	6.405e-19	91.0	COG0451@1|root,COG0451@2|Bacteria,1NXWA@1224|Proteobacteria,2TVJJ@28211|Alphaproteobacteria,2K1I2@204457|Sphingomonadales	204457|Sphingomonadales	GM	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,VKOR
GDHHQS3_k127_8242878_4	641491.DND132_1920	2.546e-24	104.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2M8EC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
GDHHQS3_k127_8242878_2	926569.ANT_14190	5.279e-56	204.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GDHHQS3_k127_8242878_3	926569.ANT_14220	5.655e-31	127.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_14220|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8242878_0	926569.ANT_14230	0.0	1385.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GDHHQS3_k127_8242878_1	926569.ANT_15750	2.568e-113	378.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GDHHQS3_k127_8280284_14	926569.ANT_04790	0.0004327	49.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.104	ko:K07273,ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_25,LysM
GDHHQS3_k127_8280284_1	926569.ANT_00050	3.893e-217	682.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GDHHQS3_k127_8280284_7	479434.Sthe_0109	8.102e-47	177.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GDHHQS3_k127_8280284_10	392500.Swoo_3464	4.834e-17	87.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,2QCNX@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GDHHQS3_k127_8280284_5	247490.KSU1_C1365	1.113e-94	325.0	COG0508@1|root,COG0508@2|Bacteria,2IWRM@203682|Planctomycetes	203682|Planctomycetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_8280284_0	1124780.ANNU01000044_gene525	1.358e-305	955.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GDHHQS3_k127_8280284_9	926569.ANT_21400	3.202e-18	86.0	COG4737@1|root,COG4737@2|Bacteria	2|Bacteria	G	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
GDHHQS3_k127_8280284_13	926569.ANT_21400	8.88e-10	60.0	COG4737@1|root,COG4737@2|Bacteria	2|Bacteria	G	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
GDHHQS3_k127_8280284_8	926569.ANT_21410	2.271e-26	111.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
GDHHQS3_k127_8280284_2	926550.CLDAP_03390	1.28e-215	688.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
GDHHQS3_k127_8280284_6	760568.Desku_1337	9.955e-54	201.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,26199@186807|Peptococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GDHHQS3_k127_8280284_3	926569.ANT_29420	4.324e-214	679.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_8280284_4	926569.ANT_29430	1.578e-159	512.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_8299615_3	926560.KE387023_gene3301	1.096e-31	127.0	COG3238@1|root,COG3238@2|Bacteria	2|Bacteria	S	Putative inner membrane exporter, YdcZ	ydcZ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
GDHHQS3_k127_8299615_2	644801.Psest_3503	3.998e-41	173.0	28IZ9@1|root,2Z8WS@2|Bacteria,1NRVI@1224|Proteobacteria,1SK35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
GDHHQS3_k127_8299615_1	485913.Krac_6225	4.017e-52	190.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GDHHQS3_k127_8299615_0	926569.ANT_25540	3.273e-163	526.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GDHHQS3_k127_8369585_3	1382306.JNIM01000001_gene3601	2.478e-111	375.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G5VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GDHHQS3_k127_8369585_9	1227739.Hsw_2470	2.586e-45	169.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GDHHQS3_k127_8369585_0	639282.DEFDS_0814	4.934e-165	530.0	COG0372@1|root,COG0372@2|Bacteria,2GEZB@200930|Deferribacteres	200930|Deferribacteres	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GDHHQS3_k127_8369585_2	639030.JHVA01000001_gene3811	8.319e-123	400.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GDHHQS3_k127_8369585_4	357808.RoseRS_0097	4.685e-105	349.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi,376IE@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GDHHQS3_k127_8369585_7	1443665.JACA01000003_gene679	2.145e-46	177.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NMWZ@976|Bacteroidetes,1I1RR@117743|Flavobacteriia,2YJ2R@290174|Aquimarina	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_8369585_6	1278073.MYSTI_05554	1.279e-49	184.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,42TJI@68525|delta/epsilon subdivisions,2WQM5@28221|Deltaproteobacteria,2Z313@29|Myxococcales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GDHHQS3_k127_8369585_10	391037.Sare_4605	2.626e-12	75.0	2A4QM@1|root,30TBX@2|Bacteria,2HU7Y@201174|Actinobacteria,4DGFU@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_8369585_8	247633.GP2143_03938	1.595e-45	174.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1JARK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GDHHQS3_k127_8369585_5	861299.J421_5887	4.685e-64	227.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GDHHQS3_k127_8369585_1	485913.Krac_0278	9.222e-128	416.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GDHHQS3_k127_8369585_11	552811.Dehly_0267	1.163e-07	55.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi,34CJN@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_839373_2	926569.ANT_28720	3.993e-113	368.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_839373_0	926569.ANT_28730	3.874e-134	443.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GDHHQS3_k127_839373_5	272568.GDI0112	3.233e-12	75.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TU56@28211|Alphaproteobacteria,2JWN9@204441|Rhodospirillales	204441|Rhodospirillales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GDHHQS3_k127_839373_1	926569.ANT_05390	4.649e-118	388.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
GDHHQS3_k127_839373_4	926569.ANT_05380	1.322e-40	153.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
GDHHQS3_k127_8407918_4	635013.TherJR_1425	5.907e-05	49.0	COG3005@1|root,COG4733@1|root,COG3005@2|Bacteria,COG4733@2|Bacteria,1UT1Y@1239|Firmicutes,250WR@186801|Clostridia,265BU@186807|Peptococcaceae	186801|Clostridia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GDHHQS3_k127_8407918_0	926569.ANT_10860	0.0	2072.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GDHHQS3_k127_8407918_2	1385519.N801_16550	9.788e-144	465.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4FEV0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36,Peptidase_M4_C
GDHHQS3_k127_8407918_3	926569.ANT_27670	1.899e-52	207.0	COG4713@1|root,COG4713@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
GDHHQS3_k127_8407918_1	402777.KB235903_gene1618	3.674e-147	475.0	COG0463@1|root,COG0463@2|Bacteria,1G4BG@1117|Cyanobacteria,1H8D9@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GDHHQS3_k127_8418396_26	357808.RoseRS_0791	4.157e-73	252.0	COG1177@1|root,COG1177@2|Bacteria,2G80I@200795|Chloroflexi,3776I@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GDHHQS3_k127_8418396_8	383372.Rcas_1237	1.812e-130	427.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi,37726@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
GDHHQS3_k127_8418396_22	1280390.CBQR020000003_gene47	1.572e-75	263.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,26UHQ@186822|Paenibacillaceae	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GDHHQS3_k127_8418396_21	324602.Caur_0188	6.212e-78	263.0	COG0693@1|root,COG0693@2|Bacteria,2GAQG@200795|Chloroflexi,375Y9@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ThiJ PfpI domain protein	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GDHHQS3_k127_8418396_5	1499967.BAYZ01000167_gene6714	1.77e-138	454.0	COG2195@1|root,COG2195@2|Bacteria,2NP2Y@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_8418396_34	314607.KB13_225	1.211e-34	132.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,2W271@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_8418396_42	443143.GM18_3520	5.948e-10	63.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_8418396_23	706587.Desti_2445	1.957e-75	254.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_8418396_10	926550.CLDAP_40620	2.713e-125	408.0	COG0169@1|root,COG0169@2|Bacteria,2G8BG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8418396_17	926550.CLDAP_40630	6.204e-88	297.0	COG0800@1|root,COG0800@2|Bacteria,2G8MI@200795|Chloroflexi	200795|Chloroflexi	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GDHHQS3_k127_8418396_7	926550.CLDAP_40640	3.203e-132	428.0	COG0111@1|root,COG0111@2|Bacteria,2G7NG@200795|Chloroflexi	200795|Chloroflexi	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GDHHQS3_k127_8418396_25	926550.CLDAP_40650	4.074e-74	253.0	COG2140@1|root,COG2140@2|Bacteria,2G9AT@200795|Chloroflexi	200795|Chloroflexi	G	Glucose-6-phosphate isomerase (GPI)	-	-	5.3.1.9	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	GPI
GDHHQS3_k127_8418396_29	1382306.JNIM01000001_gene2964	1.05e-63	230.0	COG1735@1|root,COG1735@2|Bacteria	2|Bacteria	S	zinc ion binding	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
GDHHQS3_k127_8418396_36	926550.CLDAP_32840	1.527e-29	128.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GDHHQS3_k127_8418396_0	1121957.ATVL01000007_gene1534	1.086e-236	743.0	COG2407@1|root,COG2407@2|Bacteria,4NGB6@976|Bacteroidetes,47TSI@768503|Cytophagia	976|Bacteroidetes	G	Pfam L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
GDHHQS3_k127_8418396_39	234267.Acid_5177	1.134e-21	99.0	COG0684@1|root,COG0684@2|Bacteria,3Y8I2@57723|Acidobacteria	2|Bacteria	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GDHHQS3_k127_8418396_15	1499967.BAYZ01000073_gene2038	3.176e-100	336.0	COG0524@1|root,COG0524@2|Bacteria,2NQTT@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_4062,iEcDH1_1363.EcDH1_4215	PfkB
GDHHQS3_k127_8418396_19	590998.Celf_3290	2.269e-79	278.0	COG0524@1|root,COG0524@2|Bacteria,2HXTM@201174|Actinobacteria,4F0XK@85016|Cellulomonadaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GDHHQS3_k127_8418396_35	649638.Trad_2293	3.959e-32	133.0	COG0176@1|root,COG0176@2|Bacteria,1WICB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GDHHQS3_k127_8418396_13	649638.Trad_2158	4.629e-115	378.0	COG1082@1|root,COG1082@2|Bacteria,1WKRX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
GDHHQS3_k127_8418396_11	1122611.KB904018_gene6906	1.284e-123	418.0	COG2414@1|root,COG2414@2|Bacteria,2IF1J@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GDHHQS3_k127_8418396_2	1382306.JNIM01000001_gene2968	1.937e-188	601.0	COG1070@1|root,COG1070@2|Bacteria,2G7ND@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GDHHQS3_k127_8418396_38	926550.CLDAP_40620	4.626e-23	106.0	COG0169@1|root,COG0169@2|Bacteria,2G8BG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8418396_18	1499967.BAYZ01000109_gene2982	3.557e-86	296.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_8418396_14	1121378.KB899706_gene1518	9.062e-113	373.0	COG0667@1|root,COG0667@2|Bacteria,1WJPB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GDHHQS3_k127_8418396_16	926550.CLDAP_40680	1.208e-91	309.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	ycjP	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GDHHQS3_k127_8418396_24	926550.CLDAP_40690	2.531e-75	264.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
GDHHQS3_k127_8418396_6	926550.CLDAP_40700	5.893e-133	441.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GDHHQS3_k127_8418396_30	1430331.EP10_00530	1.418e-58	212.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1WFPU@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
GDHHQS3_k127_8418396_41	684949.ATTJ01000002_gene334	2.927e-12	68.0	2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8418396_31	684949.ATTJ01000002_gene334	4.435e-52	191.0	2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8418396_33	383372.Rcas_2492	1.075e-44	169.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GDHHQS3_k127_8418396_32	316274.Haur_1699	1.946e-46	172.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GDHHQS3_k127_8418396_28	931276.Cspa_c21210	9.847e-68	237.0	COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,24M3R@186801|Clostridia,36WEC@31979|Clostridiaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_8418396_20	706587.Desti_2445	1.373e-78	263.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GDHHQS3_k127_8418396_27	485913.Krac_9362	2.76e-71	247.0	COG2186@1|root,COG2186@2|Bacteria,2G959@200795|Chloroflexi	200795|Chloroflexi	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GDHHQS3_k127_8418396_12	485913.Krac_9361	1.966e-116	381.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GDHHQS3_k127_8418396_4	485913.Krac_9360	7.8e-140	452.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
GDHHQS3_k127_8418396_3	1382306.JNIM01000001_gene2428	8.717e-170	537.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
GDHHQS3_k127_8418396_1	485913.Krac_9358	2.349e-214	672.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GDHHQS3_k127_8418396_9	485913.Krac_9357	2.112e-129	427.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GDHHQS3_k127_8418396_40	383372.Rcas_2303	6.928e-21	96.0	COG0683@1|root,COG0683@2|Bacteria,2G8P7@200795|Chloroflexi,377M1@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_8422515_6	1094715.CM001373_gene598	2.072e-26	111.0	COG2334@1|root,COG2334@2|Bacteria,1R9W9@1224|Proteobacteria,1SGNX@1236|Gammaproteobacteria,1JCMB@118969|Legionellales	118969|Legionellales	S	Phosphotransferase enzyme family	aph	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
GDHHQS3_k127_8422515_1	926569.ANT_20460	1.491e-155	508.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GDHHQS3_k127_8422515_2	926569.ANT_20590	5.395e-151	484.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
GDHHQS3_k127_8422515_3	926569.ANT_14480	1.81e-109	359.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GDHHQS3_k127_8422515_9	1158292.JPOE01000002_gene3495	1.743e-11	69.0	COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,2WFVN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GDHHQS3_k127_8422515_7	1352941.M877_19705	1.906e-24	105.0	COG1694@1|root,COG1694@2|Bacteria,2IQFH@201174|Actinobacteria	201174|Actinobacteria	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GDHHQS3_k127_8422515_4	1303518.CCALI_02921	1.82e-91	316.0	COG0517@1|root,COG1227@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
GDHHQS3_k127_8422515_5	477974.Daud_1728	6.758e-70	258.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GDHHQS3_k127_8422515_0	926569.ANT_14470	0.0	1450.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GDHHQS3_k127_8422515_10	1173263.Syn7502_03178	2.901e-10	68.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8437366_4	290397.Adeh_2071	1.016e-104	343.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_8437366_6	926569.ANT_03320	3.786e-70	242.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GDHHQS3_k127_8437366_7	313612.L8106_13140	7.953e-67	235.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria,1H91U@1150|Oscillatoriales	1117|Cyanobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GDHHQS3_k127_8437366_1	383372.Rcas_1549	1.114e-221	694.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GDHHQS3_k127_8437366_0	1254432.SCE1572_22465	1.262e-224	707.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GDHHQS3_k127_8437366_3	439235.Dalk_0563	1.268e-171	545.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2MIRN@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
GDHHQS3_k127_8437366_8	926569.ANT_03270	3.97e-54	197.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
GDHHQS3_k127_8437366_2	311424.DhcVS_737	7.547e-198	632.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GDHHQS3_k127_8437366_5	671143.DAMO_3037	1.976e-99	331.0	COG0129@1|root,COG0129@2|Bacteria,2NNSM@2323|unclassified Bacteria	2|Bacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
GDHHQS3_k127_8452072_1	926569.ANT_23120	1.106e-103	345.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GDHHQS3_k127_8452072_2	326427.Cagg_2931	2.602e-49	189.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
GDHHQS3_k127_8452072_3	1157638.KB892166_gene4740	3.119e-09	66.0	COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Terminase_5
GDHHQS3_k127_8452072_0	926550.CLDAP_20840	6.935e-248	773.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GDHHQS3_k127_8517665_1	926550.CLDAP_28640	6.018e-123	401.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GDHHQS3_k127_8517665_3	164328.Phyra41598	1.166e-88	301.0	COG0461@1|root,KOG1377@2759|Eukaryota,3Q8M9@4776|Peronosporales	4776|Peronosporales	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	2.4.2.10,4.1.1.23	ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
GDHHQS3_k127_8517665_2	926569.ANT_28360	4.511e-91	304.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GDHHQS3_k127_8517665_6	926569.ANT_28370	2.527e-50	189.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GDHHQS3_k127_8517665_9	1321778.HMPREF1982_02132	1.086e-12	70.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8517665_5	357808.RoseRS_1504	9.251e-51	188.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
GDHHQS3_k127_8517665_0	383372.Rcas_2658	1.515e-130	424.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
GDHHQS3_k127_8517665_7	485913.Krac_4710	3.369e-22	101.0	COG0477@1|root,COG2814@2|Bacteria,2G7RU@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_8517665_11	1303692.SFUL_1999	6.582e-05	50.0	COG1366@1|root,COG1366@2|Bacteria,2H996@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GDHHQS3_k127_8517665_8	525909.Afer_0221	1.079e-19	97.0	COG4242@1|root,COG4242@2|Bacteria,2HGPS@201174|Actinobacteria,4CNS6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GDHHQS3_k127_8517665_4	926550.CLDAP_18870	1.729e-81	293.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GDHHQS3_k127_8525337_24	1210884.HG799463_gene9589	5.375e-36	147.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
GDHHQS3_k127_8525337_30	1121381.JNIV01000004_gene310	6.707e-07	57.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
GDHHQS3_k127_8525337_3	926569.ANT_12750	1.145e-143	465.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
GDHHQS3_k127_8525337_25	36080.S2JLN3	4.927e-30	125.0	2BD1A@1|root,2S11B@2759|Eukaryota,3A3GN@33154|Opisthokonta,3P3WI@4751|Fungi,1GTZN@112252|Fungi incertae sedis	4751|Fungi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
GDHHQS3_k127_8525337_23	926569.ANT_16590	7.059e-39	150.0	29ATW@1|root,2ZXTA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8525337_20	743722.Sph21_1746	3.21e-51	188.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
GDHHQS3_k127_8525337_8	926569.ANT_20520	7.597e-93	316.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GDHHQS3_k127_8525337_22	926569.ANT_11850	2.665e-39	151.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GDHHQS3_k127_8525337_14	926569.ANT_11840	3.543e-69	237.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GDHHQS3_k127_8525337_2	926569.ANT_11830	4.469e-186	629.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
GDHHQS3_k127_8525337_17	926569.ANT_11820	5.213e-61	230.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
GDHHQS3_k127_8525337_21	926569.ANT_11800	2.814e-45	184.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_13	926569.ANT_11800	1.143e-70	261.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_12	926569.ANT_11800	5.041e-77	280.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_15	316274.Haur_1217	4.681e-62	240.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_8525337_28	247639.MGP2080_06962	1.139e-11	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1JARA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9,dCache_1
GDHHQS3_k127_8525337_16	926569.ANT_11800	6.601e-62	231.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_11	926569.ANT_11800	2.093e-77	281.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_29	981383.AEWH01000039_gene1783	5.294e-11	76.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	mcpA7	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
GDHHQS3_k127_8525337_7	926569.ANT_11800	3.699e-96	345.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_5	543632.JOJL01000020_gene623	4.778e-103	349.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_8525337_6	926569.ANT_11800	5.732e-103	361.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GDHHQS3_k127_8525337_10	926569.ANT_11790	3.689e-80	274.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
GDHHQS3_k127_8525337_26	1121447.JONL01000001_gene1104	1.344e-27	132.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WMD0@28221|Deltaproteobacteria,2M7R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GDHHQS3_k127_8525337_0	926569.ANT_11780	1.387e-252	816.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8525337_1	926569.ANT_11770	2.222e-235	741.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GDHHQS3_k127_8525337_9	926569.ANT_11760	1.305e-92	313.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GDHHQS3_k127_8525337_19	926569.ANT_11750	3.394e-56	207.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GDHHQS3_k127_8525337_4	926569.ANT_11740	3.036e-127	425.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi	200795|Chloroflexi	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GDHHQS3_k127_8525337_18	357808.RoseRS_0231	5.657e-58	229.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
GDHHQS3_k127_8525337_27	1450694.BTS2_1470	2.904e-27	111.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli,1ZJ93@1386|Bacillus	91061|Bacilli	S	Transcriptional Coactivator p15 (PC4)	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
GDHHQS3_k127_8549920_7	926550.CLDAP_20430	1.906e-43	164.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
GDHHQS3_k127_8549920_4	1144275.COCOR_04444	2.371e-77	264.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,42SMW@68525|delta/epsilon subdivisions,2WPP1@28221|Deltaproteobacteria,2YUYP@29|Myxococcales	28221|Deltaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GDHHQS3_k127_8549920_2	926569.ANT_19880	3.832e-132	430.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GDHHQS3_k127_8549920_11	1382359.JIAL01000001_gene2056	9.751e-14	73.0	29WS1@1|root,30ID4@2|Bacteria,3Y5IE@57723|Acidobacteria,2JK0W@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
GDHHQS3_k127_8549920_0	926569.ANT_19870	1.772e-162	517.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GDHHQS3_k127_8549920_9	1121438.JNJA01000004_gene724	6.899e-32	138.0	COG0457@1|root,COG0457@2|Bacteria,1RIYN@1224|Proteobacteria,42T31@68525|delta/epsilon subdivisions,2WPYY@28221|Deltaproteobacteria,2MAJW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
GDHHQS3_k127_8549920_3	1347392.CCEZ01000007_gene2024	3.179e-88	304.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
GDHHQS3_k127_8549920_10	765420.OSCT_1743	4.562e-23	113.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376RT@32061|Chloroflexia	32061|Chloroflexia	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GDHHQS3_k127_8549920_1	484770.UFO1_1183	2.122e-148	499.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GDHHQS3_k127_8549920_6	926569.ANT_11780	3.855e-48	195.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8549920_12	1232410.KI421419_gene2464	4.723e-13	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42PH1@68525|delta/epsilon subdivisions,2WKMX@28221|Deltaproteobacteria,43T8V@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	mrpB	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GDHHQS3_k127_8549920_8	926569.ANT_11780	2.484e-39	167.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GDHHQS3_k127_8549920_13	1198452.Jab_2c10680	2.911e-09	70.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,472DN@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GDHHQS3_k127_8549920_5	357808.RoseRS_3212	1.186e-68	243.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GDHHQS3_k127_8583638_6	1502851.FG93_04279	1.051e-84	293.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2U963@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GDHHQS3_k127_8583638_8	926569.ANT_06280	9.067e-21	98.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
GDHHQS3_k127_8583638_5	646529.Desaci_4448	1.825e-97	329.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,2618J@186807|Peptococcaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	1.1.1.335,1.1.1.370	ko:K13020,ko:K16043	ko00520,ko00562,ko01120,map00520,map00562,map01120	-	R09953,R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GDHHQS3_k127_8583638_7	33876.JNXY01000014_gene3933	9.505e-48	180.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DF0N@85008|Micromonosporales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GDHHQS3_k127_8583638_1	1174528.JH992898_gene3816	8.535e-126	412.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GDHHQS3_k127_8583638_4	926569.ANT_26220	2.734e-104	346.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	wzm	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GDHHQS3_k127_8583638_0	1148.1651974	6.517e-140	457.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H679@1142|Synechocystis	1117|Cyanobacteria	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GDHHQS3_k127_8583638_3	1173020.Cha6605_3682	1.887e-114	373.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria	1117|Cyanobacteria	JM	Glucose-1-phosphate cytidylyltransferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
GDHHQS3_k127_865135_17	926569.ANT_12100	5.698e-103	349.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
GDHHQS3_k127_865135_10	926569.ANT_12110	3.913e-143	472.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
GDHHQS3_k127_865135_2	926569.ANT_29920	4.007e-254	793.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_865135_13	926569.ANT_29920	3.308e-132	431.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GDHHQS3_k127_865135_11	926569.ANT_17820	8.515e-134	447.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GDHHQS3_k127_865135_21	926569.ANT_02710	6.251e-79	271.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
GDHHQS3_k127_865135_45	1211815.CBYP010000039_gene2596	2.153e-26	119.0	COG2306@1|root,COG2306@2|Bacteria,2GJP9@201174|Actinobacteria,4EWJZ@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF402
GDHHQS3_k127_865135_5	357808.RoseRS_3310	3.142e-219	693.0	COG0366@1|root,COG0366@2|Bacteria,2G7K6@200795|Chloroflexi,374W8@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
GDHHQS3_k127_865135_53	525373.HMPREF0766_11585	8.436e-15	77.0	COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1ITM0@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome b5-like Heme Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
GDHHQS3_k127_865135_41	1121405.dsmv_3051	2.168e-34	141.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,42WRW@68525|delta/epsilon subdivisions,2WRCW@28221|Deltaproteobacteria,2MNT0@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_12	861299.J421_6202	3.386e-133	435.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GDHHQS3_k127_865135_34	306281.AJLK01000102_gene3405	1.021e-48	178.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_48	714943.Mucpa_3931	5.786e-24	105.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,1IS6F@117747|Sphingobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GDHHQS3_k127_865135_66	479434.Sthe_0370	0.0006611	48.0	2DW90@1|root,33Z49@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_64	1410633.JHWR01000004_gene364	4.621e-05	50.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24NE7@186801|Clostridia,27NXD@186928|unclassified Lachnospiraceae	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
GDHHQS3_k127_865135_38	99598.Cal7507_1443	1.272e-39	149.0	COG4634@1|root,COG4634@2|Bacteria,1G8JH@1117|Cyanobacteria,1HQAA@1161|Nostocales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GDHHQS3_k127_865135_44	211165.AJLN01000116_gene3308	8.012e-29	118.0	COG2442@1|root,COG2442@2|Bacteria,1GI2S@1117|Cyanobacteria,1JMKD@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GDHHQS3_k127_865135_30	926560.KE387023_gene1591	3.205e-52	187.0	COG0590@1|root,COG0590@2|Bacteria,1WMK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_865135_26	220664.PFL_2481	3.738e-54	192.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,1S6BE@1236|Gammaproteobacteria,1YQPU@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_7	926569.ANT_11210	4.293e-183	586.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GDHHQS3_k127_865135_46	580327.Tthe_0305	1.898e-25	117.0	COG0739@1|root,COG0739@2|Bacteria,1UESP@1239|Firmicutes,25JS4@186801|Clostridia,42I15@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GDHHQS3_k127_865135_0	1035308.AQYY01000001_gene1943	1.239e-316	978.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GDHHQS3_k127_865135_29	330214.NIDE4175	1.392e-52	197.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
GDHHQS3_k127_865135_9	204669.Acid345_3113	1.281e-149	484.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GDHHQS3_k127_865135_37	56780.SYN_00801	1.222e-40	157.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.29	ko:K07020,ko:K18614	ko00750,ko01120,map00750,map01120	-	R01649	RC00300,RC00575	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_5,Abhydrolase_6,LIP,UPF0227
GDHHQS3_k127_865135_50	497964.CfE428DRAFT_3727	7.142e-22	101.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
GDHHQS3_k127_865135_4	926569.ANT_10600	2.325e-224	704.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GDHHQS3_k127_865135_28	926569.ANT_14050	1.131e-53	193.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GDHHQS3_k127_865135_43	867845.KI911784_gene3573	3.68e-30	123.0	COG1694@1|root,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia	32061|Chloroflexia	F	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
GDHHQS3_k127_865135_24	869210.Marky_0022	3.154e-59	218.0	COG0601@1|root,COG0601@2|Bacteria,1WIYI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GDHHQS3_k127_865135_31	373903.Hore_04920	3.206e-51	192.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WBHC@53433|Halanaerobiales	186801|Clostridia	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GDHHQS3_k127_865135_19	926569.ANT_10620	1.065e-86	304.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
GDHHQS3_k127_865135_20	926569.ANT_07600	1.882e-81	278.0	COG0483@1|root,COG0483@2|Bacteria,2G7NN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
GDHHQS3_k127_865135_39	926569.ANT_31070	2.607e-39	153.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
GDHHQS3_k127_865135_16	485916.Dtox_2632	3.296e-103	344.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GDHHQS3_k127_865135_52	1122218.KB893654_gene2307	7.227e-15	81.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2U2X2@28211|Alphaproteobacteria,1JRW5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2
GDHHQS3_k127_865135_65	317619.ANKN01000027_gene1700	0.0003338	52.0	COG4254@1|root,COG4254@2|Bacteria,1G662@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
GDHHQS3_k127_865135_14	926569.ANT_18180	4.739e-127	417.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GDHHQS3_k127_865135_27	316274.Haur_4498	3.742e-54	196.0	COG0491@1|root,COG0491@2|Bacteria,2G8K6@200795|Chloroflexi,377BH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GDHHQS3_k127_865135_32	479434.Sthe_2201	4.194e-51	190.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GDHHQS3_k127_865135_15	926569.ANT_18190	8.572e-105	348.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GDHHQS3_k127_865135_36	1040986.ATYO01000001_gene1764	4.795e-45	177.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TS7M@28211|Alphaproteobacteria,43R9I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
GDHHQS3_k127_865135_49	1298858.AUEL01000002_gene1693	6.651e-24	108.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,43H16@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS3_k127_865135_40	292459.STH2262	5.607e-39	165.0	COG3385@1|root,COG3385@2|Bacteria,1VJRW@1239|Firmicutes,24U4P@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
GDHHQS3_k127_865135_42	631454.N177_2381	3.044e-33	132.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,1JP59@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GDHHQS3_k127_865135_33	1207063.P24_08614	2.867e-50	190.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,2JS0G@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GDHHQS3_k127_865135_25	1282876.BAOK01000002_gene562	6.387e-58	214.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,4BPP3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11069,ko:K11073	ko02010,map02010	M00299,M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1,3.A.1.11.2	-	-	SBP_bac_8
GDHHQS3_k127_865135_54	63737.Npun_R5155	3.351e-14	74.0	28PC1@1|root,2ZC4I@2|Bacteria,1G51C@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_57	41431.PCC8801_4267	4.778e-10	65.0	28PC1@1|root,2ZC4I@2|Bacteria,1G51C@1117|Cyanobacteria,3KHW6@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_865135_8	926569.ANT_18200	9.291e-157	501.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GDHHQS3_k127_865135_22	926569.ANT_18220	1.859e-73	252.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GDHHQS3_k127_865135_3	926569.ANT_18230	1.161e-248	779.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GDHHQS3_k127_865135_18	926569.ANT_18240	1.815e-96	319.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GDHHQS3_k127_865135_60	425104.Ssed_2863	2.819e-07	55.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,2QCTT@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Iron-sulphur cluster assembly	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
GDHHQS3_k127_865135_55	926569.ANT_18250	3.508e-14	81.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_34
GDHHQS3_k127_865135_23	926550.CLDAP_02830	1.464e-60	212.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GDHHQS3_k127_865135_1	926569.ANT_16350	2.258e-298	926.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GDHHQS3_k127_865135_56	1123508.JH636447_gene7822	2.745e-13	82.0	COG4961@1|root,COG4961@2|Bacteria,2IXIS@203682|Planctomycetes	203682|Planctomycetes	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GDHHQS3_k127_865135_61	748727.CLJU_c28850	5.342e-07	57.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,36MCG@31979|Clostridiaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS3_k127_865135_35	1385517.N800_00720	3.403e-45	188.0	COG1361@1|root,COG3188@1|root,COG1361@2|Bacteria,COG3188@2|Bacteria,1R5G4@1224|Proteobacteria,1T61M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GDHHQS3_k127_865135_51	225849.swp_0420	1.504e-15	89.0	COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria	1224|Proteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GDHHQS3_k127_865135_59	867903.ThesuDRAFT_00034	2.169e-09	64.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS3_k127_865135_63	525904.Tter_1023	8.146e-06	58.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GDHHQS3_k127_865135_58	926550.CLDAP_35680	9.318e-10	68.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GDHHQS3_k127_865135_6	926569.ANT_11050	8.245e-186	589.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GDHHQS3_k127_8801209_2	926554.KI912628_gene2716	1.449e-25	108.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GDHHQS3_k127_8801209_0	504728.K649_15010	1.579e-96	323.0	COG2309@1|root,COG2309@2|Bacteria,1WI5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS3_k127_8801209_3	1134510.O9A_00542	8.311e-24	109.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,2TSGB@28211|Alphaproteobacteria,48T1A@772|Bartonellaceae	28211|Alphaproteobacteria	E	Thermophilic metalloprotease (M29)	ampS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS3_k127_8801209_1	665952.HMPREF1015_00917	7.358e-83	280.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus	91061|Bacilli	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GDHHQS3_k127_8893259_3	926569.ANT_25090	8.066e-41	156.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_8893259_0	926569.ANT_25100	9.712e-234	739.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GDHHQS3_k127_8893259_1	251229.Chro_4000	7.951e-73	252.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GDHHQS3_k127_8893259_2	264732.Moth_1000	3.961e-61	227.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GDHHQS3_k127_8961721_0	926569.ANT_14390	6.897e-178	567.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GDHHQS3_k127_8961721_1	926569.ANT_18420	5.912e-137	469.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
GDHHQS3_k127_8961721_3	926569.ANT_18410	4.979e-40	158.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GDHHQS3_k127_8961721_2	926569.ANT_12990	4.083e-81	278.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
GDHHQS3_k127_908738_10	1056816.JAFQ01000004_gene1005	1.881e-10	62.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria,4G3VK@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
GDHHQS3_k127_908738_0	1306990.BARG01000093_gene9131	3.72e-183	575.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
GDHHQS3_k127_908738_2	526225.Gobs_3499	1.061e-137	445.0	COG1028@1|root,COG1028@2|Bacteria,2HGC6@201174|Actinobacteria,4EUGC@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GDHHQS3_k127_908738_3	99598.Cal7507_5535	5.311e-129	419.0	COG2207@1|root,COG2207@2|Bacteria,1G0B1@1117|Cyanobacteria,1HKZ5@1161|Nostocales	1117|Cyanobacteria	K	AraC-type transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
GDHHQS3_k127_908738_9	1089546.AQUI01000002_gene250	1.416e-16	85.0	2E3TC@1|root,32YQV@2|Bacteria,2GXYE@201174|Actinobacteria	201174|Actinobacteria	S	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
GDHHQS3_k127_908738_7	926550.CLDAP_27170	1.484e-80	284.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
GDHHQS3_k127_908738_4	1192868.CAIU01000026_gene3649	7.419e-100	336.0	COG4177@1|root,COG4177@2|Bacteria,1PKHQ@1224|Proteobacteria,2U113@28211|Alphaproteobacteria,43I7I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_908738_5	1192868.CAIU01000026_gene3648	1.467e-97	327.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,43P9I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GDHHQS3_k127_908738_6	479434.Sthe_2876	3.817e-81	277.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,27Y8Q@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_908738_8	479434.Sthe_2877	7.832e-72	250.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi,27YUS@189775|Thermomicrobia	189775|Thermomicrobia	P	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GDHHQS3_k127_908738_1	1192868.CAIU01000026_gene3646	1.204e-145	472.0	COG0683@1|root,COG0683@2|Bacteria,1R9V4@1224|Proteobacteria,2VF9C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GDHHQS3_k127_909934_2	478741.JAFS01000002_gene159	2.331e-32	130.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia,37GNT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
GDHHQS3_k127_909934_0	926569.ANT_14180	9.81e-119	401.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GDHHQS3_k127_909934_1	926569.ANT_14170	1.811e-74	254.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GDHHQS3_k127_96519_4	926569.ANT_29480	2.442e-25	107.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GDHHQS3_k127_96519_2	316274.Haur_1815	8.305e-124	424.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi,377ZW@32061|Chloroflexia	32061|Chloroflexia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
GDHHQS3_k127_96519_3	926569.ANT_07440	6.72e-89	302.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
GDHHQS3_k127_96519_1	635013.TherJR_1798	1.451e-174	576.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25ZXM@186807|Peptococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GDHHQS3_k127_96519_0	502025.Hoch_4658	8.69e-189	614.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
GDHHQS3_k127_96519_5	754476.Q7A_488	2.72e-11	68.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
GDHHQS3_k127_96519_6	1121015.N789_09455	0.00021	52.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 4202 queries scanned
## Total time (seconds): 256.5040681362152
## Rate: 16.38 q/s