## Wed Oct 16 15:03:07 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/GGS1_bin.9.fa -m mmseqs --itype genome -o GGS1_bin.9 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/GGS1_bin.9 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GGS1_k127_1013637_6	997884.HMPREF1068_00362	0.0001069	56.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
GGS1_k127_1013637_5	102129.Lepto7375DRAFT_0842	6.787e-06	60.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,1G4UG@1117|Cyanobacteria,1HH6U@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
GGS1_k127_1013637_0	1236689.MMALV_11840	4.288e-83	293.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,3F2I5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
GGS1_k127_1013637_4	304371.MCP_1506	1.377e-08	63.0	COG1761@1|root,arCOG04111@2157|Archaea,2XYYQ@28890|Euryarchaeota,2NA0Z@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoL	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
GGS1_k127_1013637_3	439481.Aboo_1190	1.583e-14	86.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GGS1_k127_1013637_7	682795.AciX8_2332	0.0003753	52.0	COG3188@1|root,COG3188@2|Bacteria,3Y42P@57723|Acidobacteria,2JI9K@204432|Acidobacteriia	204432|Acidobacteriia	NU	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GGS1_k127_1013637_2	1054217.TALC_00153	2.567e-48	188.0	COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,241PC@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_Crp_2
GGS1_k127_1013637_1	673860.AciM339_0957	1.292e-65	240.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,3F2J9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Nucleolar GTP-binding protein 1 (NOG1)	gbp4	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
GGS1_k127_1027245_0	266117.Rxyl_3115	3.708e-28	119.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4CPRS@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GGS1_k127_1029667_1	1183377.Py04_1340	2.553e-54	195.0	COG0444@1|root,arCOG00181@2157|Archaea,2XSTM@28890|Euryarchaeota,242V4@183968|Thermococci	183968|Thermococci	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GGS1_k127_1029667_0	867903.ThesuDRAFT_01380	1.91e-89	320.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GGS1_k127_1040416_0	1236689.MMALV_16620	6.727e-229	740.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2G4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GGS1_k127_1040416_1	269797.Mbar_A0182	2.358e-32	132.0	COG2016@1|root,arCOG00985@2157|Archaea,2XX1R@28890|Euryarchaeota,2N9WM@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM PUA domain containing protein	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	DUF1947,PUA
GGS1_k127_1040416_3	439481.Aboo_0757	4.092e-24	111.0	COG2450@1|root,arCOG02263@2157|Archaea,2XXYF@28890|Euryarchaeota,3F3BW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Pfam:DUF552	sepF	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
GGS1_k127_1040416_2	673860.AciM339_0005	2.056e-24	114.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2Y701@28890|Euryarchaeota,3F31J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	toxin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1040416_4	673860.AciM339_0010	6.356e-09	67.0	COG1361@1|root,arCOG01917@1|root,arCOG05791@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG04400@2157|Archaea,arCOG05791@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
GGS1_k127_1042523_7	593117.TGAM_0264	0.0004082	44.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,243A5@183968|Thermococci	183968|Thermococci	C	sulfur compound binding	vorB	-	1.2.7.7	ko:K00187	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C
GGS1_k127_1042523_1	673860.AciM339_0763	9.924e-56	201.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GGS1_k127_1042523_0	1121468.AUBR01000064_gene940	3.088e-109	372.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,42EUF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GGS1_k127_1042523_3	272844.PAB1471	2.05e-26	112.0	COG1144@1|root,arCOG01605@2157|Archaea,2XY2F@28890|Euryarchaeota,245HQ@183968|Thermococci	183968|Thermococci	C	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	vorD	-	1.2.7.7	ko:K00188	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
GGS1_k127_1042523_2	1125863.JAFN01000001_gene2836	1.209e-44	176.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GGS1_k127_1042523_6	484770.UFO1_4033	1.778e-05	53.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,4H5P1@909932|Negativicutes	909932|Negativicutes	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
GGS1_k127_1042523_5	1236689.MMALV_11500	3.134e-08	60.0	COG0375@1|root,arCOG04426@2157|Archaea,2XYBI@28890|Euryarchaeota,3F2U7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GGS1_k127_1042523_4	479434.Sthe_2499	5.103e-25	114.0	29JD5@1|root,306AN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1047417_2	1236689.MMALV_10380	2.443e-38	150.0	COG2516@1|root,arCOG00662@2157|Archaea,2XV52@28890|Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GGS1_k127_1047417_3	1303518.CCALI_01335	7.088e-06	59.0	COG4272@1|root,COG4272@2|Bacteria	2|Bacteria	S	membrane	ywjH	-	-	-	-	-	-	-	-	-	-	-	DUF1634
GGS1_k127_1047417_0	278957.ABEA03000006_gene4188	9.466e-54	199.0	COG0730@1|root,COG0730@2|Bacteria,46V52@74201|Verrucomicrobia,3K9AP@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GGS1_k127_1047417_4	1041826.FCOL_03030	0.0003609	53.0	2BW99@1|root,2Z7PD@2|Bacteria,4PBRA@976|Bacteroidetes,1ICMB@117743|Flavobacteriia,2NT6K@237|Flavobacterium	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1047417_1	439481.Aboo_0519	3.736e-47	174.0	COG0463@1|root,arCOG01385@2157|Archaea,2XUEP@28890|Euryarchaeota,3F30S@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	aglI	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GGS1_k127_1054672_2	693661.Arcve_1470	3.227e-41	166.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,246UJ@183980|Archaeoglobi	183980|Archaeoglobi	N	PFAM Type II secretion system F domain	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
GGS1_k127_1054672_0	673860.AciM339_1271	1.358e-171	567.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,3F31Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	flaI	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GGS1_k127_1054672_1	1094980.Mpsy_2349	7.24e-63	224.0	COG2874@1|root,arCOG04148@2157|Archaea,2XUMD@28890|Euryarchaeota,2N9IB@224756|Methanomicrobia	224756|Methanomicrobia	N	KaiC	-	-	-	ko:K07331	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ATPase
GGS1_k127_1054672_5	439481.Aboo_1320	4.91e-09	64.0	COG3354@1|root,arCOG01822@2157|Archaea,2Y176@28890|Euryarchaeota,3F3BF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Archaebacterial flagellin	-	-	-	ko:K07330	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
GGS1_k127_1054672_6	1455608.JDTH01000002_gene293	2.91e-08	61.0	COG3353@1|root,arCOG01824@2157|Archaea,2XYQP@28890|Euryarchaeota,23WWZ@183963|Halobacteria	183963|Halobacteria	N	archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
GGS1_k127_1054672_4	439481.Aboo_0143	3.162e-16	91.0	COG3351@1|root,arCOG02964@2157|Archaea,2XVP0@28890|Euryarchaeota,3F2YQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Flagella accessory protein C (FlaC)	flaD	-	-	ko:K07327,ko:K07328	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_fla_DE,FlaC_arch
GGS1_k127_1054672_3	246969.TAM4_1683	2.326e-16	87.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,2431K@183968|Thermococci	183968|Thermococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB4	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
GGS1_k127_1056189_3	1094980.Mpsy_0417	1.862e-08	68.0	arCOG02516@1|root,arCOG02538@1|root,arCOG03439@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,arCOG03439@2157|Archaea	2157|Archaea	L	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CHB_HEX_C_1,PKD,PQQ_3,Peptidase_S8
GGS1_k127_1056189_1	459349.CLOAM0437	1.362e-63	249.0	COG0457@1|root,COG0457@2|Bacteria	459349.CLOAM0437|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1056189_0	1485544.JQKP01000001_gene1154	8.431e-82	291.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,44W3P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GGS1_k127_1056189_2	593750.Metfor_1540	2.478e-30	138.0	COG1392@1|root,arCOG02640@2157|Archaea	2157|Archaea	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GGS1_k127_1056189_4	1150864.MILUP08_41339	3.541e-06	59.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D96C@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
GGS1_k127_1065739_2	671143.DAMO_1987	1.497e-12	76.0	COG2259@1|root,COG2259@2|Bacteria,2NQ4C@2323|unclassified Bacteria	2|Bacteria	S	DoxX	ndh	-	1.6.99.3,1.8.5.2	ko:K03885,ko:K16937	ko00190,ko00920,ko01120,map00190,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD,DoxX,Pyr_redox_2
GGS1_k127_1065739_0	1227484.C471_13321	2.871e-42	170.0	COG0704@1|root,arCOG00318@2157|Archaea,2XT7D@28890|Euryarchaeota,23SX0@183963|Halobacteria	183963|Halobacteria	K	Phosphate uptake regulator	phoU5	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
GGS1_k127_1065739_1	1276756.AUEX01000004_gene2516	1.821e-17	89.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,4AF2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GGS1_k127_1110943_0	66874.JOFS01000006_gene4287	4.253e-19	103.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
GGS1_k127_1115957_16	211165.AJLN01000039_gene1873	3.123e-08	65.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1JHQJ@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_1115957_7	1236689.MMALV_00040	2.546e-46	173.0	COG2131@1|root,arCOG01487@2157|Archaea,2XXBC@28890|Euryarchaeota,3F2KA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GGS1_k127_1115957_9	439481.Aboo_0002	2.331e-35	150.0	COG0681@1|root,arCOG01739@2157|Archaea,2Y6XH@28890|Euryarchaeota,3F2QN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
GGS1_k127_1115957_1	439481.Aboo_0001	8.497e-141	471.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,AAA_22,Cdc6_C
GGS1_k127_1115957_5	593117.TGAM_0269	1.305e-62	232.0	COG2262@1|root,arCOG00353@2157|Archaea,2XT2W@28890|Euryarchaeota,2431W@183968|Thermococci	183968|Thermococci	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GGS1_k127_1115957_8	648996.Theam_1436	4.831e-40	158.0	COG2231@1|root,COG2231@2|Bacteria,2G41H@200783|Aquificae	200783|Aquificae	L	PFAM HhH-GPD family protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
GGS1_k127_1115957_12	1094980.Mpsy_2612	1.167e-28	128.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_1115957_17	67352.JODS01000020_gene3882	7.472e-08	65.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria	201174|Actinobacteria	E	IA, variant 3	hisE	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GGS1_k127_1115957_2	439481.Aboo_1085	5.878e-133	443.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,3F2HC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Radical_SAM C-terminal domain	elp3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GGS1_k127_1115957_10	1094980.Mpsy_1303	3.879e-35	137.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2N9YG@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GGS1_k127_1115957_13	1120999.JONM01000012_gene2242	4.238e-12	81.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG2373@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG2373@2|Bacteria,COG4733@2|Bacteria,1QV7E@1224|Proteobacteria,2WHIN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
GGS1_k127_1115957_4	439481.Aboo_0699	2.23e-102	350.0	COG0403@1|root,arCOG00077@2157|Archaea,2XT39@28890|Euryarchaeota,3F362@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Glycine cleavage system P-protein	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GGS1_k127_1115957_0	529709.PYCH_18260	5.156e-171	571.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GGS1_k127_1115957_14	416348.Hlac_1082	7.055e-12	71.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GGS1_k127_1115957_18	1033806.HTIA_2082	1.362e-05	51.0	arCOG07990@1|root,arCOG07990@2157|Archaea,2XZBP@28890|Euryarchaeota,23X0K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1115957_6	439481.Aboo_1535	3.593e-58	212.0	COG1378@1|root,arCOG02038@2157|Archaea,2Y7FZ@28890|Euryarchaeota,3F2ZR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
GGS1_k127_1115957_15	1054217.TALC_00434	9.948e-11	65.0	COG1145@1|root,arCOG02460@2157|Archaea	2157|Archaea	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIL
GGS1_k127_1115957_3	263820.PTO0896	6.986e-126	415.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,241M8@183967|Thermoplasmata	183967|Thermoplasmata	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
GGS1_k127_1115957_11	269797.Mbar_A2412	1.388e-32	146.0	COG2042@1|root,arCOG04733@2157|Archaea,2XVBD@28890|Euryarchaeota,2N9PH@224756|Methanomicrobia	224756|Methanomicrobia	J	pre-rRNA processing protein involved in ribosome biogenesis	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
GGS1_k127_1126173_2	1227453.C444_12737	4.852e-07	53.0	arCOG10731@1|root,arCOG10731@2157|Archaea	2157|Archaea	S	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
GGS1_k127_1126173_0	1449126.JQKL01000017_gene2771	5.025e-19	100.0	COG0103@1|root,COG1305@1|root,COG0103@2|Bacteria,COG1305@2|Bacteria,1VEK4@1239|Firmicutes,25EFA@186801|Clostridia	186801|Clostridia	J	PFAM Copper amine	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
GGS1_k127_1126173_1	1254432.SCE1572_15255	2.191e-11	70.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2YUZY@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
GGS1_k127_1153113_6	670487.Ocepr_1834	1.432e-33	133.0	COG0573@1|root,COG0573@2|Bacteria,1WIA6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GGS1_k127_1153113_3	266117.Rxyl_0820	3.142e-56	212.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GGS1_k127_1153113_2	1459636.NTE_00043	3.88e-109	359.0	COG1117@1|root,arCOG00231@2157|Archaea,41SYJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GGS1_k127_1153113_4	1408422.JHYF01000006_gene1214	1.359e-47	182.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,36FX2@31979|Clostridiaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GGS1_k127_1153113_0	469381.Dpep_0405	4.999e-211	679.0	COG0855@1|root,COG0855@2|Bacteria,3TAC8@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GGS1_k127_1153113_1	456442.Mboo_1456	5.891e-146	499.0	COG0248@1|root,arCOG05138@2157|Archaea,2XZYT@28890|Euryarchaeota,2NAE7@224756|Methanomicrobia	224756|Methanomicrobia	F	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GGS1_k127_1153113_7	864702.OsccyDRAFT_1191	4.978e-06	53.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1H968@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
GGS1_k127_1153113_5	1459636.NTE_02673	1.162e-36	147.0	arCOG01449@1|root,arCOG01449@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1161082_2	309800.C498_09646	9.58e-08	58.0	arCOG07990@1|root,arCOG07990@2157|Archaea,2XZBP@28890|Euryarchaeota,23X0K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1161082_1	1227497.C491_06923	7.295e-17	87.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GGS1_k127_1161082_0	439481.Aboo_0158	6.415e-65	229.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,3F2GM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GGS1_k127_1169992_1	1449044.JMLE01000035_gene452	2.681e-87	297.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GGS1_k127_1169992_0	439481.Aboo_0538	1.044e-140	458.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,3F2GD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	GTPase of unknown function C-terminal	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
GGS1_k127_1171314_1	926569.ANT_06940	5.57e-69	243.0	COG0842@1|root,COG0842@2|Bacteria,2G8MV@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GGS1_k127_1171314_0	1158318.ATXC01000001_gene1138	5.15e-92	317.0	COG0215@1|root,COG0215@2|Bacteria,2G3JG@200783|Aquificae	200783|Aquificae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GGS1_k127_1171314_2	1123023.JIAI01000003_gene2736	3.896e-26	123.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GGS1_k127_1171954_1	404589.Anae109_0051	3.241e-21	108.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,42QER@68525|delta/epsilon subdivisions,2WM9B@28221|Deltaproteobacteria,2Z2AM@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GGS1_k127_1171954_2	797299.HALLA_10205	2.114e-13	84.0	arCOG04668@1|root,arCOG04668@2157|Archaea,2XVFU@28890|Euryarchaeota,23T5V@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1171954_0	1459636.NTE_00104	7.336e-119	395.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GGS1_k127_1171954_3	644282.Deba_0970	1.146e-06	56.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydratas,OB_aCoA_assoc
GGS1_k127_1178164_3	608538.HTH_0938	6.961e-32	127.0	COG1136@1|root,COG1136@2|Bacteria,2G3W9@200783|Aquificae	200783|Aquificae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_1178164_5	1048339.KB913029_gene2528	8.409e-13	83.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GGS1_k127_1178164_1	1449126.JQKL01000003_gene1757	7.942e-95	325.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,267Z6@186813|unclassified Clostridiales	186801|Clostridia	G	Dehydrogenase E1 component	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
GGS1_k127_1178164_0	1121423.JONT01000003_gene978	8.086e-99	333.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GGS1_k127_1178164_4	682795.AciX8_3695	3.905e-23	106.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
GGS1_k127_1178164_6	1499967.BAYZ01000041_gene2349	2.895e-06	52.0	2EQ2A@1|root,33HNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1178164_2	1121324.CLIT_13c01150	3.423e-90	301.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25QSS@186804|Peptostreptococcaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GGS1_k127_1181345_1	439481.Aboo_0184	1.07e-73	255.0	COG1500@1|root,arCOG04187@2157|Archaea,2XTNH@28890|Euryarchaeota,3F2JN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
GGS1_k127_1181345_0	673860.AciM339_0865	2.929e-96	321.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,3F2G0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
GGS1_k127_1191790_1	404589.Anae109_2325	5.951e-16	93.0	COG1572@1|root,COG2885@1|root,COG2911@1|root,COG3209@1|root,COG1572@2|Bacteria,COG2885@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,1PFUJ@1224|Proteobacteria,430XP@68525|delta/epsilon subdivisions,2WW66@28221|Deltaproteobacteria	2|Bacteria	M	TIGRFAM YD repeat protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Calx-beta,DctA-YdbH,RHS_repeat
GGS1_k127_1191790_0	693661.Arcve_1550	2.62e-17	92.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_1194072_0	688269.Theth_0526	1.342e-64	237.0	COG0136@1|root,COG0136@2|Bacteria	2|Bacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.2.1.11,1.2.1.12	ko:K00133,ko:K00134	ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010	M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552	R01061,R02291	RC00149,RC00684	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N,Semialdhyde_dh,Semialdhyde_dhC
GGS1_k127_1194239_1	304371.MCP_2778	5.649e-36	154.0	COG1784@1|root,arCOG04469@2157|Archaea,2XSZ3@28890|Euryarchaeota,2N9A6@224756|Methanomicrobia	224756|Methanomicrobia	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K08971	-	-	-	-	ko00000	-	-	-	TctA
GGS1_k127_1194239_0	643648.Slip_2197	4.737e-78	267.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42JIV@68298|Syntrophomonadaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GGS1_k127_1201510_0	351160.RCIX575	3.449e-164	536.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
GGS1_k127_1201510_1	1094980.Mpsy_0730	1.083e-41	173.0	COG3291@1|root,COG3420@1|root,COG3979@1|root,arCOG02508@2157|Archaea,arCOG02519@2157|Archaea,arCOG02546@2157|Archaea,arCOG07581@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_1214886_2	237368.SCABRO_03033	1.297e-46	192.0	COG1838@1|root,COG1838@2|Bacteria,2J14Y@203682|Planctomycetes	203682|Planctomycetes	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
GGS1_k127_1214886_0	648996.Theam_0603	7.2e-91	310.0	COG1951@1|root,COG1951@2|Bacteria,2G3JI@200783|Aquificae	200783|Aquificae	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
GGS1_k127_1214886_1	1183438.GKIL_3640	5.83e-62	226.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1GBPU@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
GGS1_k127_1222913_1	2074.JNYD01000014_gene7088	0.0008077	46.0	COG1545@1|root,COG1545@2|Bacteria,2H97T@201174|Actinobacteria,4ED90@85010|Pseudonocardiales	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	OB_aCoA_assoc
GGS1_k127_1222913_0	404589.Anae109_2163	1.2e-122	405.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_1233693_0	1410666.JHXG01000007_gene2082	2.112e-10	72.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,2FPG0@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GGS1_k127_1237823_1	673860.AciM339_0044	5.374e-31	127.0	COG0162@1|root,arCOG01886@2157|Archaea,2XTA0@28890|Euryarchaeota,3F2HA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
GGS1_k127_1237823_0	1236689.MMALV_05930	1.084e-136	465.0	COG0343@1|root,COG1370@1|root,arCOG00989@2157|Archaea,arCOG00991@2157|Archaea,2XTFH@28890|Euryarchaeota,3F2F8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PUA,TGT,TGT_C1,TGT_C2
GGS1_k127_1245998_1	70601.3258336	1.523e-51	190.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
GGS1_k127_1245998_2	5888.CAK83391	7.017e-43	173.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
GGS1_k127_1245998_3	693661.Arcve_0149	2.506e-09	71.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
GGS1_k127_1245998_0	673860.AciM339_0364	1.178e-64	231.0	COG0388@1|root,arCOG00062@2157|Archaea,2XT6R@28890|Euryarchaeota,3F2PP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Carbon-nitrogen hydrolase	-	-	3.5.1.100	ko:K18540	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
GGS1_k127_1266385_1	709986.Deima_0947	2.961e-15	88.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_1266385_2	398767.Glov_0506	2.76e-11	71.0	COG0526@1|root,COG0526@2|Bacteria,1RHR7@1224|Proteobacteria,42WV1@68525|delta/epsilon subdivisions,2WSIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GGS1_k127_1266385_0	224325.AF_2060	3.992e-103	342.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,24622@183980|Archaeoglobi	183980|Archaeoglobi	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Intein_splicing,Rep_fac_C,RuvB_N
GGS1_k127_1266717_0	406124.ACPC01000017_gene625	9.657e-77	292.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
GGS1_k127_1269405_2	673860.AciM339_0749	1.191e-38	160.0	COG0517@1|root,COG0750@1|root,arCOG00607@2157|Archaea,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
GGS1_k127_1269405_3	273116.14324649	3.467e-22	103.0	arCOG03678@1|root,arCOG03677@2157|Archaea,2Y0K5@28890|Euryarchaeota,242AH@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1269405_5	67373.JOBF01000003_gene340	2.308e-07	58.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GGS1_k127_1269405_1	1094980.Mpsy_0258	7.344e-46	174.0	COG1634@1|root,arCOG04303@2157|Archaea,2XT8R@28890|Euryarchaeota,2N9JZ@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
GGS1_k127_1269405_4	1054217.TALC_01497	1.215e-14	76.0	COG1383@1|root,arCOG01885@2157|Archaea,2Y07I@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
GGS1_k127_1269405_0	195522.BD01_0924	1.419e-144	492.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
GGS1_k127_1269405_6	1227453.C444_18882	7.428e-07	58.0	COG0109@1|root,arCOG03103@2157|Archaea,2Y58X@28890|Euryarchaeota,240IW@183963|Halobacteria	183963|Halobacteria	O	Cytochrome oxidase assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	COX15-CtaA
GGS1_k127_1269405_7	479434.Sthe_3168	4.023e-05	50.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GGS1_k127_1275731_0	1236689.MMALV_16390	7.803e-68	240.0	COG2108@1|root,arCOG00932@2157|Archaea,2XU78@28890|Euryarchaeota,3F2FA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K07129	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
GGS1_k127_1275731_1	351160.RCIX2357	1.895e-51	205.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,2N9DZ@224756|Methanomicrobia	224756|Methanomicrobia	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GGS1_k127_128426_1	1151117.AJLF01000001_gene831	1.235e-97	325.0	COG1884@1|root,arCOG04232@2157|Archaea,2XU3F@28890|Euryarchaeota,24324@183968|Thermococci	183968|Thermococci	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GGS1_k127_128426_0	867845.KI911784_gene840	9.313e-201	634.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GGS1_k127_129031_0	1379698.RBG1_1C00001G0453	7.753e-201	634.0	COG1053@1|root,COG1053@2|Bacteria,2NNR9@2323|unclassified Bacteria	2|Bacteria	C	succinate dehydrogenase, flavoprotein subunit	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GGS1_k127_129031_1	1267534.KB906759_gene1791	3.391e-52	195.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_129031_2	1220534.B655_1048	5.583e-30	140.0	arCOG02499@1|root,arCOG02501@1|root,arCOG02499@2157|Archaea,arCOG02501@2157|Archaea,2Y0FJ@28890|Euryarchaeota	28890|Euryarchaeota	O	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	NosD
GGS1_k127_1293236_1	1448857.JFAP01000007_gene365	0.0001124	46.0	COG1832@1|root,COG2761@1|root,COG1832@2|Bacteria,COG2761@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2YPC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GGS1_k127_1293236_0	593750.Metfor_1649	1.999e-180	628.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_129571_1	742823.HMPREF9465_01660	4.299e-60	214.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,4PQU3@995019|Sutterellaceae	28216|Betaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
GGS1_k127_129571_0	593750.Metfor_2272	1.519e-91	316.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2NB23@224756|Methanomicrobia	224756|Methanomicrobia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
GGS1_k127_1312946_5	997346.HMPREF9374_2943	2.263e-23	103.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,27CJT@186824|Thermoactinomycetaceae	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran
GGS1_k127_1312946_2	1007103.AFHW01000126_gene553	7.533e-57	216.0	COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli,26S4X@186822|Paenibacillaceae	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GGS1_k127_1312946_4	1209989.TepiRe1_0842	7.343e-35	141.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,42G3N@68295|Thermoanaerobacterales	186801|Clostridia	E	cyclohydrolase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
GGS1_k127_1312946_0	1499967.BAYZ01000152_gene1402	5.409e-107	355.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GGS1_k127_1312946_3	304371.MCP_0143	9.584e-48	186.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,2N9R4@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_1312946_1	1054217.TALC_00438	1.796e-83	290.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,241M6@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GGS1_k127_1312946_6	1384054.N790_08905	2.652e-14	83.0	COG4760@1|root,COG4760@2|Bacteria,1REUF@1224|Proteobacteria,1T1EH@1236|Gammaproteobacteria,1XD49@135614|Xanthomonadales	135614|Xanthomonadales	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
GGS1_k127_1322427_0	1463858.JOHR01000010_gene3733	1.828e-05	58.0	COG3325@1|root,COG3325@2|Bacteria,2GJGW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	chtA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,Glyco_hydro_18,fn3
GGS1_k127_1329400_1	398580.Dshi_2002	4.792e-06	59.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria,2U0PC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_1329400_0	797303.Natpe_1497	4.471e-20	104.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
GGS1_k127_1340733_0	338966.Ppro_0340	4.082e-156	509.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,43SVB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
GGS1_k127_1340733_1	1009370.ALO_08635	1.681e-93	325.0	COG0651@1|root,COG0651@2|Bacteria,1TTBD@1239|Firmicutes,4H21C@909932|Negativicutes	909932|Negativicutes	CP	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
GGS1_k127_1340733_3	575540.Isop_0367	1.99e-31	138.0	COG4237@1|root,COG4237@2|Bacteria,2J10M@203682|Planctomycetes	203682|Planctomycetes	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
GGS1_k127_1340733_2	404589.Anae109_3782	1.371e-81	280.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,2Z0BP@29|Myxococcales	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0374,iAF987.Gmet_2600	NADHdh
GGS1_k127_134911_0	1125863.JAFN01000001_gene2057	2.203e-162	518.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GGS1_k127_134911_3	591158.SSMG_03418	4.388e-15	85.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942,ko:K21172	ko01057,ko01059,ko01130,map01057,map01059,map01130	M00781,M00825	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
GGS1_k127_134911_4	565033.GACE_1886	5.532e-11	74.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota,24737@183980|Archaeoglobi	183980|Archaeoglobi	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GGS1_k127_134911_1	1379698.RBG1_1C00001G0071	5.518e-74	266.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	kefB	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2
GGS1_k127_134911_2	292459.STH2626	1.378e-30	139.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
GGS1_k127_1349613_0	373994.Riv7116_0975	1.197e-31	134.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,1HNIS@1161|Nostocales	1117|Cyanobacteria	S	ADP-ribosylation factor family	-	-	-	-	-	-	-	-	-	-	-	-	Ras,Roc
GGS1_k127_1349613_1	693661.Arcve_1550	1.188e-18	89.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_1349613_2	1500894.JQNN01000001_gene1172	1.602e-05	51.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,472YR@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GGS1_k127_1353449_1	304371.MCP_1454	2.613e-49	185.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,2N9J0@224756|Methanomicrobia	224756|Methanomicrobia	H	TIGRFAM riboflavin synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GGS1_k127_1353449_2	673860.AciM339_0317	4.08e-44	177.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
GGS1_k127_1353449_0	573063.Metin_1020	2.939e-59	213.0	COG0108@1|root,arCOG01320@2157|Archaea,2XTDZ@28890|Euryarchaeota,23Q9J@183939|Methanococci	183939|Methanococci	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
GGS1_k127_1356423_4	186497.PF0473	2.008e-29	124.0	COG0533@1|root,arCOG01185@2157|Archaea,2XX5D@28890|Euryarchaeota,2436E@183968|Thermococci	183968|Thermococci	T	serine threonine protein kinase	-	GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	RIO1
GGS1_k127_1356423_2	69014.TK2111	6.737e-54	199.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,243RS@183968|Thermococci	183968|Thermococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GGS1_k127_1356423_0	477974.Daud_0117	3.068e-85	293.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,25ZZU@186807|Peptococcaceae	186801|Clostridia	C	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GGS1_k127_1356423_3	1382306.JNIM01000001_gene2904	3.649e-45	172.0	COG2320@1|root,COG2320@2|Bacteria,2G94B@200795|Chloroflexi	200795|Chloroflexi	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
GGS1_k127_1356423_1	350688.Clos_2127	1.306e-82	292.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,36EI0@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
GGS1_k127_13768_0	1298593.TOL_1324	2.993e-17	98.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GGS1_k127_13768_1	870187.Thini_1774	2.096e-11	79.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GGS1_k127_13768_2	1121928.AUHE01000017_gene163	0.000747	50.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4GC97@85026|Gordoniaceae	201174|Actinobacteria	S	MMPL family	mmpL13	-	-	ko:K06994,ko:K20466	-	-	-	-	ko00000,ko02000	2.A.6.5.5	-	-	MMPL
GGS1_k127_1379948_4	1041930.Mtc_0455	1.594e-42	172.0	COG1781@1|root,arCOG04229@2157|Archaea,2XWP4@28890|Euryarchaeota,2N9RS@224756|Methanomicrobia	224756|Methanomicrobia	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
GGS1_k127_1379948_0	439481.Aboo_1121	2.761e-112	374.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,3F2F5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1168	OTCace,OTCace_N
GGS1_k127_1379948_2	272557.APE_0304.1	1.845e-81	300.0	COG0747@1|root,arCOG01533@2157|Archaea,2XSNM@28889|Crenarchaeota	28889|Crenarchaeota	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	PKD,SBP_bac_5
GGS1_k127_1379948_1	439481.Aboo_1254	8.831e-90	307.0	COG0601@1|root,arCOG00751@2157|Archaea,2XTRU@28890|Euryarchaeota,3F32E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GGS1_k127_1379948_3	926550.CLDAP_13040	1.019e-59	226.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GGS1_k127_13802_0	1144275.COCOR_02646	1.434e-53	197.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_1384185_1	521011.Mpal_2379	2.802e-32	128.0	COG0148@1|root,arCOG01169@2157|Archaea,2XSXT@28890|Euryarchaeota,2NAG2@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GGS1_k127_1384185_0	1236689.MMALV_07730	6.943e-139	459.0	COG0015@1|root,arCOG01747@2157|Archaea,2XUQ5@28890|Euryarchaeota,3F2GT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
GGS1_k127_1384185_3	1500259.JQLD01000002_gene3008	1.031e-20	109.0	COG2202@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG2202@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1QUXB@1224|Proteobacteria,2TWTY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347
GGS1_k127_1384185_2	415426.Hbut_0262	1.844e-28	126.0	COG1437@1|root,arCOG01723@2157|Archaea,2XQWN@28889|Crenarchaeota	28889|Crenarchaeota	F	adenylyl cyclase CyaB	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GGS1_k127_1389218_2	391615.ABSJ01000054_gene1379	0.0003239	54.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1J5BG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
GGS1_k127_1389218_1	673860.AciM339_0279	1.409e-30	128.0	COG1599@1|root,arCOG01510@2157|Archaea,2Y72Y@28890|Euryarchaeota,3F3AT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
GGS1_k127_1389218_0	673860.AciM339_0759	1.313e-36	151.0	COG1468@1|root,arCOG00786@2157|Archaea,2Y71A@28890|Euryarchaeota,3F34X@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	TIGRFAM CRISPR-associated protein Cas4	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_1
GGS1_k127_1400173_1	1236689.MMALV_07810	9.058e-22	98.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1400173_0	439481.Aboo_0917	2.535e-127	422.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,3F2HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GGS1_k127_1411891_2	1168289.AJKI01000030_gene1168	3.667e-05	52.0	COG1051@1|root,COG1051@2|Bacteria,4NSQ1@976|Bacteroidetes,2FU0I@200643|Bacteroidia,3XKB3@558415|Marinilabiliaceae	976|Bacteroidetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GGS1_k127_1411891_0	997346.HMPREF9374_2906	1.553e-36	145.0	COG0500@1|root,COG0500@2|Bacteria,1V1KE@1239|Firmicutes	1239|Firmicutes	Q	Methyltransferase	tehB	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	DUF1971,Methyltransf_25,TehB
GGS1_k127_1411891_1	797303.Natpe_1948	1.16e-21	103.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XVHG@28890|Euryarchaeota,23SZN@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
GGS1_k127_1415258_1	456442.Mboo_1987	7.781e-37	147.0	COG0301@1|root,arCOG00038@2157|Archaea,2XYMB@28890|Euryarchaeota,2NBHY@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI
GGS1_k127_1415258_0	456442.Mboo_1985	2.865e-77	271.0	COG0476@1|root,arCOG01676@2157|Archaea,2XTYV@28890|Euryarchaeota,2N9IZ@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
GGS1_k127_1428205_0	880073.Calab_0526	4.896e-10	74.0	COG1404@1|root,COG3291@1|root,COG3386@1|root,COG5276@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17,3.2.1.4	ko:K01053,ko:K01179,ko:K07214,ko:K12287	ko00030,ko00053,ko00500,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00500,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751,R06200,R11307,R11308	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko02044,ko04147	-	GH5,GH9	-	Big_5,DUF285,Esterase,He_PIG,SGL
GGS1_k127_1485034_0	439481.Aboo_0964	1.246e-143	464.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F31W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GGS1_k127_1485034_1	439481.Aboo_0865	7.226e-09	61.0	COG2443@1|root,arCOG02204@2157|Archaea,2Y6IU@28890|Euryarchaeota,3F2UZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	TIGRFAM protein translocase SEC61 complex gamma subunit	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
GGS1_k127_1494512_0	1347368.HG964403_gene4490	3.788e-41	177.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
GGS1_k127_1525392_0	335541.Swol_0786	2.526e-128	422.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42JP3@68298|Syntrophomonadaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GGS1_k127_1525392_3	526225.Gobs_2476	9.498e-20	94.0	COG0454@1|root,COG0454@2|Bacteria,2HX8M@201174|Actinobacteria,4EUEX@85013|Frankiales	201174|Actinobacteria	K	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
GGS1_k127_1525392_1	1123023.JIAI01000003_gene2950	1.406e-47	182.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4DZTV@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GGS1_k127_1525392_5	1206732.BAGD01000097_gene4156	5.499e-08	62.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4G2TT@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GGS1_k127_1525392_4	1123258.AQXZ01000017_gene3839	3.915e-09	64.0	COG2197@1|root,COG3832@1|root,COG2197@2|Bacteria,COG3832@2|Bacteria,2I51C@201174|Actinobacteria,4G1H4@85025|Nocardiaceae	2|Bacteria	K	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Polyketide_cyc2,Response_reg
GGS1_k127_1525392_2	1184267.A11Q_2038	9.217e-28	127.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,42PTT@68525|delta/epsilon subdivisions,2MT5U@213481|Bdellovibrionales,2WS13@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Zn_pept	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
GGS1_k127_1566985_3	56780.SYN_00081	3.173e-55	203.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2MQXP@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	Nitro_FeMo-Co,ParA
GGS1_k127_1566985_2	273116.14324865	1.092e-87	306.0	COG0665@1|root,arCOG00755@2157|Archaea,2Y66F@28890|Euryarchaeota,24239@183967|Thermoplasmata	183967|Thermoplasmata	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GGS1_k127_1566985_4	247490.KSU1_B0560	8.055e-12	71.0	COG1917@1|root,COG1917@2|Bacteria,2J4BF@203682|Planctomycetes	203682|Planctomycetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1566985_0	379066.GAU_1670	1.232e-104	375.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GGS1_k127_1566985_5	1323663.AROI01000016_gene497	5.48e-08	65.0	COG0642@1|root,COG0642@2|Bacteria,1Q6FW@1224|Proteobacteria,1RZ50@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
GGS1_k127_1566985_1	933801.Ahos_0309	7.298e-103	353.0	COG1960@1|root,arCOG04310@2157|Archaea,2XPUV@28889|Crenarchaeota	28889|Crenarchaeota	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_1582340_0	935837.JAEK01000003_gene4042	4.778e-85	289.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	mmgC	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_1614257_3	338966.Ppro_3526	5.099e-12	79.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WNT3@28221|Deltaproteobacteria,43UYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
GGS1_k127_1614257_1	1033806.HTIA_2023	1.142e-83	297.0	COG0651@1|root,arCOG01537@2157|Archaea,2XU88@28890|Euryarchaeota,23S0I@183963|Halobacteria	183963|Halobacteria	C	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
GGS1_k127_1614257_0	926569.ANT_22080	8.849e-115	391.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	926569.ANT_22080|-	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1614257_5	338966.Ppro_3528	5.102e-05	52.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
GGS1_k127_1614257_4	1111729.ATYV01000011_gene391	2.154e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,22K1X@1653|Corynebacteriaceae	201174|Actinobacteria	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GGS1_k127_1620366_0	562970.Btus_0199	2.304e-100	337.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,2784N@186823|Alicyclobacillaceae	91061|Bacilli	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GGS1_k127_1620366_1	589924.Ferp_2374	2.488e-98	336.0	COG1208@1|root,arCOG00668@2157|Archaea,2Y87G@28890|Euryarchaeota,2462R@183980|Archaeoglobi	183980|Archaeoglobi	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GGS1_k127_162073_0	1459636.NTE_03463	3.852e-141	464.0	COG1055@1|root,arCOG00238@2157|Archaea	2157|Archaea	P	Citrate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	CitMHS,Na_sulph_symp
GGS1_k127_162073_1	1521187.JPIM01000137_gene2066	7.521e-120	396.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GGS1_k127_162073_2	224325.AF_0556	0.0003438	43.0	COG0425@1|root,arCOG02062@2157|Archaea,2XZUG@28890|Euryarchaeota,246G4@183980|Archaeoglobi	183980|Archaeoglobi	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
GGS1_k127_1626647_0	926550.CLDAP_21600	4.233e-30	123.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GGS1_k127_162868_0	1236689.MMALV_12580	3.271e-116	385.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,3F2I6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	C-terminal region of MMR_HSR1 domain	drg	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
GGS1_k127_1657841_1	368408.Tpen_0369	8.876e-21	100.0	COG1514@1|root,arCOG01736@2157|Archaea,2XQM6@28889|Crenarchaeota	28889|Crenarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GGS1_k127_1657841_0	1121481.AUAS01000006_gene877	2.115e-31	143.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
GGS1_k127_1663629_0	1236689.MMALV_07250	3.131e-09	64.0	arCOG02981@1|root,arCOG02981@2157|Archaea,2Y4VF@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1671193_6	991.IW20_20685	3.962e-06	62.0	COG1361@1|root,COG4447@1|root,COG4733@1|root,COG5492@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,4PAKE@976|Bacteroidetes,1IN20@117743|Flavobacteriia,2NXAW@237|Flavobacterium	976|Bacteroidetes	MN	domain, Protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	-
GGS1_k127_1671193_1	40559.M7U2B3	5.014e-53	217.0	COG2319@1|root,KOG0272@1|root,KOG0263@2759|Eukaryota,KOG0272@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q3UV@4751|Fungi,3RKXV@4890|Ascomycota	4751|Fungi	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,PNP_UDP_1,WD40
GGS1_k127_1671193_4	118173.KB235914_gene1474	9.434e-09	70.0	COG2911@1|root,COG2931@1|root,COG3391@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G2NP@1117|Cyanobacteria,1H73B@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,HemolysinCabind
GGS1_k127_1671193_5	298653.Franean1_1350	1.634e-08	70.0	COG3209@1|root,COG3209@2|Bacteria,2I35N@201174|Actinobacteria,4EUHA@85013|Frankiales	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
GGS1_k127_1671193_2	330214.NIDE1591	4.433e-45	176.0	COG3359@1|root,COG3359@2|Bacteria,3J137@40117|Nitrospirae	40117|Nitrospirae	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GGS1_k127_1671193_0	1094980.Mpsy_0044	3.056e-73	268.0	COG3273@1|root,arCOG01963@2157|Archaea,2XSXK@28890|Euryarchaeota,2N9C2@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM TrkA-C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoU,TrkA_C
GGS1_k127_1671193_3	1236689.MMALV_13850	1.437e-21	106.0	COG1824@1|root,arCOG00624@2157|Archaea,2XTEI@28890|Euryarchaeota,3F2SF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	Divalent cation transporter	-	-	-	ko:K07244	-	-	-	-	ko00000,ko02000	1.A.26.3	-	-	MgtE
GGS1_k127_1681968_4	1385515.N791_09635	8.567e-14	83.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,1X41B@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GGS1_k127_1681968_3	645991.Sgly_0859	1.321e-37	156.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes,247NG@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GGS1_k127_1681968_6	485914.Hmuk_3148	0.0001507	56.0	COG3979@1|root,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
GGS1_k127_1681968_5	272559.BF9343_3219	7.31e-06	60.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GGS1_k127_1681968_1	673860.AciM339_0169	1.347e-61	216.0	COG2236@1|root,arCOG00040@2157|Archaea,2XU0E@28890|Euryarchaeota,3F38W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphoribosyl transferase domain	-	-	2.4.2.22	ko:K00769,ko:K07101	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GGS1_k127_1681968_0	673860.AciM339_0357	2.723e-99	331.0	COG0005@1|root,arCOG01327@2157|Archaea,2XUJX@28890|Euryarchaeota,3F2GH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Purine nucleoside phosphorylase involved in purine salvage	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GGS1_k127_1681968_2	1041930.Mtc_0609	8.373e-39	158.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GGS1_k127_1683048_1	1125863.JAFN01000001_gene3281	3.47e-51	191.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WMNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GGS1_k127_1683048_0	575540.Isop_2272	3.243e-107	358.0	COG0451@1|root,COG0451@2|Bacteria,2IWW0@203682|Planctomycetes	203682|Planctomycetes	GM	NAD- dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GGS1_k127_1683048_2	485913.Krac_11777	4.211e-08	54.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GGS1_k127_168535_0	926554.KI912640_gene1374	1.754e-135	446.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GGS1_k127_168535_2	1521187.JPIM01000023_gene799	6.232e-23	111.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_168535_3	314265.R2601_15632	4.34e-18	99.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_170556_1	439481.Aboo_0507	4.435e-101	347.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,3F2FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
GGS1_k127_170556_0	673860.AciM339_0566	4.017e-101	340.0	COG0731@1|root,arCOG04174@2157|Archaea,2XSTF@28890|Euryarchaeota,3F2ET@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
GGS1_k127_1715417_0	944564.HMPREF9200_0280	2.805e-70	244.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H2XI@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GGS1_k127_1756025_0	1280390.CBQR020000114_gene2966	2.117e-09	72.0	COG1470@1|root,COG3664@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3664@2|Bacteria,COG5492@2|Bacteria,1UWN0@1239|Firmicutes,4I6C2@91061|Bacilli,26S1I@186822|Paenibacillaceae	91061|Bacilli	G	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,NPCBM_assoc
GGS1_k127_1770290_0	1487923.DP73_08310	6.043e-58	210.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BFV@186801|Clostridia,263RU@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GGS1_k127_1770290_1	519442.Huta_2200	1.956e-45	183.0	COG2086@1|root,arCOG00446@2157|Archaea,2XTB8@28890|Euryarchaeota,23TTZ@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GGS1_k127_177055_0	1254432.SCE1572_12170	2.952e-113	377.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
GGS1_k127_177055_1	502025.Hoch_5093	2.125e-45	174.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GGS1_k127_177055_2	444157.Tneu_0647	7.712e-35	143.0	COG1748@1|root,arCOG00243@2157|Archaea,2XQJJ@28889|Crenarchaeota	28889|Crenarchaeota	C	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP,Semialdhyde_dh,UDPG_MGDP_dh_N
GGS1_k127_177926_4	224325.AF_0535	1.878e-13	77.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,245QE@183980|Archaeoglobi	183980|Archaeoglobi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GGS1_k127_177926_6	673860.AciM339_0078	0.0002651	49.0	COG3609@1|root,arCOG06966@2157|Archaea,2Y5GZ@28890|Euryarchaeota,3F3D2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	RHH_1
GGS1_k127_177926_3	351160.RCIX1840	1.591e-17	90.0	COG0784@1|root,arCOG02391@2157|Archaea,2Y6EC@28890|Euryarchaeota,2NBEQ@224756|Methanomicrobia	224756|Methanomicrobia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GGS1_k127_177926_1	439481.Aboo_0558	1.851e-47	187.0	arCOG13525@1|root,arCOG13525@2157|Archaea,2Y72N@28890|Euryarchaeota,3F3A7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_177926_5	765912.Thimo_1752	2.703e-10	73.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,1X1H2@135613|Chromatiales	135613|Chromatiales	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_177926_2	351160.RCIX703	1.797e-24	113.0	arCOG03142@1|root,arCOG03142@2157|Archaea,2XTSE@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_177926_0	479434.Sthe_2380	5.262e-120	402.0	COG0513@1|root,COG0513@2|Bacteria,2G5VR@200795|Chloroflexi,27XXB@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GGS1_k127_1787874_2	1144275.COCOR_05003	4.255e-42	158.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GGS1_k127_1787874_1	404589.Anae109_2522	2.86e-47	189.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GGS1_k127_1787874_0	439481.Aboo_1446	8.519e-60	231.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,3F2WK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GGS1_k127_1791134_0	521011.Mpal_0546	2.255e-63	225.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,2N98Y@224756|Methanomicrobia	224756|Methanomicrobia	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
GGS1_k127_1791134_1	673860.AciM339_0301	7.448e-22	98.0	COG2139@1|root,arCOG04129@2157|Archaea,2XXZB@28890|Euryarchaeota,3F2TG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
GGS1_k127_1791134_2	1041930.Mtc_2249	1.83e-14	78.0	COG1460@1|root,arCOG01016@2157|Archaea,2XXZX@28890|Euryarchaeota,2N9UM@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM RNA polymerase Rpb4	rpoF	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
GGS1_k127_1791134_3	673860.AciM339_0303	3.121e-08	62.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,3F2KH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Helix-hairpin-helix motif	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
GGS1_k127_1795897_2	1120960.ATXG01000009_gene79	4.197e-15	84.0	COG2234@1|root,COG2234@2|Bacteria,2HFF1@201174|Actinobacteria,4FK8Z@85023|Microbacteriaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GGS1_k127_1795897_0	479434.Sthe_2181	3.294e-77	279.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GGS1_k127_1795897_3	1382306.JNIM01000001_gene678	3.235e-05	55.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GGS1_k127_1795897_1	1379698.RBG1_1C00001G0683	1.78e-18	90.0	COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria	2|Bacteria	P	(Rieske (2Fe-2S) domain)	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GGS1_k127_181674_5	155864.EDL933_0566	0.0003827	53.0	COG2373@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	von willebrand factor, type A	lapA	-	-	ko:K12549	-	-	-	-	ko00000	-	-	-	Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VCBS,VWA,VWA_2
GGS1_k127_181674_3	1123057.P872_00785	4.398e-06	59.0	COG0545@1|root,COG0545@2|Bacteria,4NTM6@976|Bacteroidetes,47RMV@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GGS1_k127_181674_0	1054217.TALC_01406	2.334e-109	363.0	COG0057@1|root,arCOG00493@2157|Archaea,2XT16@28890|Euryarchaeota,241JM@183967|Thermoplasmata	183967|Thermoplasmata	G	4-hydroxy-tetrahydrodipicolinate reductase	gap	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
GGS1_k127_181674_4	344747.PM8797T_30576	2.01e-05	56.0	COG0454@1|root,COG0456@2|Bacteria,2IZQZ@203682|Planctomycetes	203682|Planctomycetes	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_181674_1	622637.KE124774_gene1793	1.836e-13	81.0	COG2362@1|root,COG2362@2|Bacteria,1QH4F@1224|Proteobacteria,2U3TC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GGS1_k127_181674_2	1131269.AQVV01000005_gene376	4.369e-07	60.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GGS1_k127_1823171_7	439481.Aboo_0017	3.31e-30	125.0	COG1326@1|root,arCOG02680@2157|Archaea,2XUFW@28890|Euryarchaeota,3F2TD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal Zn-finger protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1823171_4	673860.AciM339_0455	2.05e-48	183.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,3F2J0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	iAF692.Mbar_A2900	TP_methylase
GGS1_k127_1823171_2	386456.JQKN01000001_gene2183	6.001e-110	369.0	COG1635@1|root,arCOG00574@2157|Archaea,2XTXH@28890|Euryarchaeota	28890|Euryarchaeota	H	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
GGS1_k127_1823171_5	1449346.JQMO01000003_gene2362	7.829e-41	157.0	COG0789@1|root,COG0789@2|Bacteria,2GNJE@201174|Actinobacteria,2M1WU@2063|Kitasatospora	201174|Actinobacteria	KL	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GGS1_k127_1823171_1	1236689.MMALV_07230	2.781e-117	390.0	COG0520@1|root,arCOG00065@2157|Archaea,2XSYI@28890|Euryarchaeota	2157|Archaea	E	Cysteine desulfurase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GGS1_k127_1823171_3	342949.PNA2_1458	3.784e-75	270.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,242SX@183968|Thermococci	183968|Thermococci	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GGS1_k127_1823171_8	439481.Aboo_0021	8.782e-25	117.0	COG1522@1|root,arCOG01580@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1823171_0	1041930.Mtc_1540	1.881e-146	492.0	COG1855@1|root,arCOG04116@2157|Archaea,2XSZY@28890|Euryarchaeota,2N924@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM PilT protein domain protein	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,PIN,T2SSE
GGS1_k127_1823171_6	342949.PNA2_0161	2.352e-30	129.0	COG2428@1|root,arCOG00968@2157|Archaea,2XVH8@28890|Euryarchaeota,242IZ@183968|Thermococci	183968|Thermococci	S	Predicted SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_Me_trans
GGS1_k127_1825552_0	589924.Ferp_1988	4.428e-73	255.0	COG1384@1|root,arCOG00485@2157|Archaea,2XTR5@28890|Euryarchaeota,245RR@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
GGS1_k127_1825552_1	439481.Aboo_1417	4.955e-57	211.0	COG0856@1|root,arCOG00028@2157|Archaea,2XU2R@28890|Euryarchaeota,3F30G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	pyrE1	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GGS1_k127_1825552_2	1449063.JMLS01000021_gene846	9.767e-29	126.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	ugpQ_2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GGS1_k127_1825552_3	1069080.KB913028_gene1738	1.181e-13	77.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes	909932|Negativicutes	I	glutaconyl-CoA decarboxylase subunit gamma	gcdC	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Biotin_lipoyl
GGS1_k127_1833483_0	1118054.CAGW01000037_gene898	3.671e-249	783.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GGS1_k127_183488_1	1382356.JQMP01000003_gene1346	5.998e-31	133.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi,27XUP@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GGS1_k127_183488_0	673860.AciM339_0303	4.52e-62	218.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,3F2KH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Helix-hairpin-helix motif	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
GGS1_k127_1853162_0	1041930.Mtc_2505	4.095e-27	120.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,2N9GP@224756|Methanomicrobia	224756|Methanomicrobia	J	pfam nmd3	-	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
GGS1_k127_1853162_1	1227352.C173_08606	3.744e-08	66.0	COG5297@1|root,COG5297@2|Bacteria,1TXPR@1239|Firmicutes,4I6QI@91061|Bacilli,26UAT@186822|Paenibacillaceae	91061|Bacilli	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
GGS1_k127_1853162_2	1121921.KB898707_gene1015	2.899e-05	57.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_5,Cadherin,Cadherin_3,He_PIG,OMP_b-brl,OmpA_membrane,fn3
GGS1_k127_1854414_6	673860.AciM339_1090	1.406e-07	57.0	arCOG03397@1|root,arCOG03397@2157|Archaea,2Y76W@28890|Euryarchaeota,3F3HH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1854414_0	673860.AciM339_0552	5.361e-104	348.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
GGS1_k127_1854414_2	1184251.TCELL_0468	2.256e-14	84.0	COG0382@1|root,arCOG00476@2157|Archaea,2XQNM@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM UbiA prenyltransferase	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
GGS1_k127_1854414_4	1121935.AQXX01000142_gene2222	1.762e-09	72.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	OmpA MotB	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GGS1_k127_1854414_5	1089551.KE386572_gene1743	8.314e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_1854414_3	941449.dsx2_2245	5.273e-11	71.0	COG2020@1|root,COG2020@2|Bacteria,1PK5Y@1224|Proteobacteria,43E9G@68525|delta/epsilon subdivisions,2WZHZ@28221|Deltaproteobacteria,2MDZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GGS1_k127_1854414_1	195250.CM001776_gene1080	1.097e-94	324.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1G03V@1117|Cyanobacteria,1GZ6A@1129|Synechococcus	1117|Cyanobacteria	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
GGS1_k127_1861972_2	452637.Oter_2942	9.415e-29	134.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
GGS1_k127_1861972_0	1457250.BBMO01000001_gene1581	4.601e-45	186.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_1861972_1	391625.PPSIR1_03638	5.651e-36	157.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	1224|Proteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_1863062_0	648996.Theam_0146	1.661e-109	368.0	COG0165@1|root,COG0165@2|Bacteria,2G3PT@200783|Aquificae	200783|Aquificae	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
GGS1_k127_1863062_3	1382306.JNIM01000001_gene3428	3.882e-11	77.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,Pkinase,TIR_2,WD40
GGS1_k127_1863062_1	751944.HALDL1_10370	3.913e-35	141.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXD4@28890|Euryarchaeota,23VSD@183963|Halobacteria	183963|Halobacteria	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
GGS1_k127_1863062_2	797299.HALLA_04740	2.864e-17	83.0	COG0183@1|root,arCOG01278@2157|Archaea,2XVUA@28890|Euryarchaeota,23TVK@183963|Halobacteria	183963|Halobacteria	I	COG0183 Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GGS1_k127_1874686_0	1379698.RBG1_1C00001G0054	1.81e-185	586.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
GGS1_k127_1874686_1	479434.Sthe_0840	1.404e-67	240.0	COG0327@1|root,COG0327@2|Bacteria,2G9ZR@200795|Chloroflexi,27XXV@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_1874686_3	273075.Ta0785	1.923e-12	76.0	COG3371@1|root,arCOG02008@2157|Archaea,2Y1QQ@28890|Euryarchaeota,242HN@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GGS1_k127_1874686_2	1380386.JIAW01000004_gene71	9.686e-59	218.0	COG3396@1|root,COG3396@2|Bacteria,2GK2T@201174|Actinobacteria,23CT4@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GGS1_k127_1881264_0	543632.JOJL01000005_gene4790	8.958e-06	57.0	COG4733@1|root,COG5434@1|root,COG4733@2|Bacteria,COG5434@2|Bacteria,2I9IV@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3,fn3
GGS1_k127_1931000_0	589924.Ferp_2554	6.839e-139	460.0	COG0183@1|root,arCOG01280@2157|Archaea,2Y2DA@28890|Euryarchaeota,246KU@183980|Archaeoglobi	183980|Archaeoglobi	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_N
GGS1_k127_1931000_1	589924.Ferp_2555	8.122e-117	390.0	COG0183@1|root,arCOG01279@2157|Archaea,2Y2G9@28890|Euryarchaeota,246XN@183980|Archaeoglobi	183980|Archaeoglobi	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
GGS1_k127_1931000_2	1227276.HMPREF9148_00296	2.252e-06	57.0	COG0546@1|root,COG0546@2|Bacteria,4NNJ1@976|Bacteroidetes,2G32S@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GGS1_k127_1934452_2	756883.Halar_2393	1.267e-61	224.0	COG0452@1|root,arCOG01704@2157|Archaea	2157|Archaea	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GGS1_k127_1934452_5	1197130.BAFM01000011_gene2093	7.16e-32	136.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,23SPN@183963|Halobacteria	183963|Halobacteria	S	kinase, sugar kinase superfamily	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
GGS1_k127_1934452_8	696281.Desru_1536	1.726e-05	51.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,24JH9@186801|Clostridia,260KT@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
GGS1_k127_1934452_3	648996.Theam_1191	2.17e-53	203.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GGS1_k127_1934452_7	28115.HR11_07770	3.624e-30	139.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,2FN5W@200643|Bacteroidia,22W0A@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GGS1_k127_1934452_9	446462.Amir_6298	7.829e-05	52.0	COG0346@1|root,COG0346@2|Bacteria,2IHX4@201174|Actinobacteria,4E4SJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_1934452_6	573063.Metin_0746	1.381e-30	131.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,23QUN@183939|Methanococci	183939|Methanococci	J	PFAM methyltransferase small	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,PrmA
GGS1_k127_1934452_1	1121472.AQWN01000003_gene1405	4.234e-104	351.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,261AS@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GGS1_k127_1934452_0	1054217.TALC_00553	0.0	1232.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,241KM@183967|Thermoplasmata	183967|Thermoplasmata	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GGS1_k127_1934452_4	644966.Tmar_0901	8.478e-46	171.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
GGS1_k127_1940355_1	304371.MCP_2684	3.1e-36	140.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,2N9CI@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GGS1_k127_1940355_0	1054217.TALC_00716	1.688e-77	273.0	COG1474@1|root,arCOG00467@2157|Archaea,2Y0SQ@28890|Euryarchaeota,242CI@183967|Thermoplasmata	183967|Thermoplasmata	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
GGS1_k127_1940889_0	997346.HMPREF9374_3504	8.211e-161	551.0	COG1112@1|root,COG2852@1|root,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli,27CB1@186824|Thermoactinomycetaceae	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
GGS1_k127_1964599_5	351160.LRC398	1.524e-20	99.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,2N9PA@224756|Methanomicrobia	224756|Methanomicrobia	I	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GGS1_k127_1964599_1	673860.AciM339_0397	5.056e-89	306.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GGS1_k127_1964599_4	673860.AciM339_0396	1.275e-27	119.0	COG0794@1|root,arCOG00068@2157|Archaea,2XX86@28890|Euryarchaeota,3F2MP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	SIS domain	-	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
GGS1_k127_1964599_3	1230460.C495_17177	2.698e-33	142.0	COG0697@1|root,arCOG00271@2157|Archaea,2XTYP@28890|Euryarchaeota,23TQ4@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GGS1_k127_1964599_2	877455.Metbo_2056	4.053e-67	245.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWVA@28890|Euryarchaeota	28890|Euryarchaeota	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_1964599_0	868131.MSWAN_0582	1.035e-93	331.0	COG0842@1|root,arCOG01463@2157|Archaea,2XWB7@28890|Euryarchaeota,23PY9@183925|Methanobacteria	183925|Methanobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GGS1_k127_1964599_6	1324957.K933_16552	1.149e-09	68.0	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG07560@1|root,arCOG02499@2157|Archaea,arCOG02508@2157|Archaea,arCOG07560@2157|Archaea,arCOG07581@2157|Archaea,2Y80Y@28890|Euryarchaeota,24124@183963|Halobacteria	183963|Halobacteria	G	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_1981959_1	309807.SRU_1675	9.477e-27	123.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1FJJV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GGS1_k127_1981959_0	1210884.HG799476_gene15385	7.918e-43	175.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
GGS1_k127_1989428_0	1242864.D187_002164	4.091e-15	90.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,43C7K@68525|delta/epsilon subdivisions,2X7HW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of unknown function	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3
GGS1_k127_1989428_1	406552.NJ7G_3736	8.685e-07	61.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,23UR0@183963|Halobacteria	183963|Halobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24
GGS1_k127_1989731_0	572546.Arcpr_1593	2.295e-81	280.0	COG0380@1|root,arCOG02831@2157|Archaea,2XSTE@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0380 Trehalose-6-phosphate synthase	otsA	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
GGS1_k127_1989731_1	1007104.SUS17_1384	2.301e-56	216.0	COG2270@1|root,COG2270@2|Bacteria,1QWEU@1224|Proteobacteria,2U333@28211|Alphaproteobacteria,2K8VZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_1989731_2	1459636.NTE_01921	1.753e-49	189.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GGS1_k127_1989731_4	1087448.Eab7_1636	2.006e-19	98.0	COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,3WFPB@539002|Bacillales incertae sedis	91061|Bacilli	S	Protein of unknown function (DUF1405)	ypjA	-	-	-	-	-	-	-	-	-	-	-	DUF1405
GGS1_k127_1989731_3	866536.Belba_1164	6.974e-45	167.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,47K1F@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GGS1_k127_1991954_4	324602.Caur_3444	2.832e-09	63.0	COG0438@1|root,COG0438@2|Bacteria,2GB6N@200795|Chloroflexi,37545@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_1991954_0	526227.Mesil_1024	2.519e-49	182.0	COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_1991954_2	1320556.AVBP01000004_gene3674	3.54e-24	109.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GGS1_k127_1991954_1	1144275.COCOR_00436	7.299e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,1N1QR@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_1998218_1	1121272.KB903256_gene5552	0.0002074	54.0	COG2133@1|root,COG3291@1|root,COG3507@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4D8ZK@85008|Micromonosporales	201174|Actinobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,GSDH,PKD,ThuA
GGS1_k127_1998218_0	415426.Hbut_0632	1.949e-54	201.0	COG2518@1|root,arCOG00976@2157|Archaea,2XPYU@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GGS1_k127_2012804_0	485913.Krac_12597	2.819e-84	298.0	COG0477@1|root,COG2814@2|Bacteria,2G5SP@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GGS1_k127_2012804_1	485913.Krac_11134	4.488e-35	135.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GGS1_k127_2051951_6	593750.Metfor_1087	4.138e-06	55.0	COG1534@1|root,arCOG01346@2157|Archaea,2Y6W9@28890|Euryarchaeota,2NA5I@224756|Methanomicrobia	224756|Methanomicrobia	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
GGS1_k127_2051951_3	1094980.Mpsy_1492	4.91e-15	79.0	COG2023@1|root,arCOG04345@2157|Archaea,2XYX0@28890|Euryarchaeota,2NA13@224756|Methanomicrobia	224756|Methanomicrobia	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
GGS1_k127_2051951_8	1261545.MBE-HAL_0001	9.516e-05	52.0	arCOG01881@1|root,arCOG01881@2157|Archaea,2XVW7@28890|Euryarchaeota,23TXZ@183963|Halobacteria	183963|Halobacteria	I	COG0170 Dolichol kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2051951_4	358396.C445_07360	5.456e-07	59.0	arCOG01881@1|root,arCOG01881@2157|Archaea,2XVW7@28890|Euryarchaeota,23TXZ@183963|Halobacteria	183963|Halobacteria	I	COG0170 Dolichol kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2051951_7	1123354.AUDR01000013_gene529	2.14e-05	53.0	COG2461@1|root,COG2461@2|Bacteria,1QWG2@1224|Proteobacteria,2WGYM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GGS1_k127_2051951_0	1379698.RBG1_1C00001G0892	6.813e-105	350.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
GGS1_k127_2051951_2	748247.AZKH_2147	8.996e-50	187.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GGS1_k127_2051951_1	477974.Daud_0885	2.03e-59	217.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,261IU@186807|Peptococcaceae	186801|Clostridia	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GGS1_k127_2051951_5	1105031.HMPREF1141_3247	3.296e-06	50.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,36F30@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GGS1_k127_2078271_2	264462.Bd2866	0.000509	54.0	COG3898@1|root,COG3898@2|Bacteria	2|Bacteria	D	HemY domain protein	-	-	-	ko:K01991,ko:K02498	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	He_PIG
GGS1_k127_2078271_0	273075.Ta0520	1.608e-21	109.0	COG1836@1|root,arCOG02245@2157|Archaea,2XTBR@28890|Euryarchaeota,241UU@183967|Thermoplasmata	183967|Thermoplasmata	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GGS1_k127_2078271_1	373994.Riv7116_5903	2.386e-17	92.0	COG0382@1|root,COG0382@2|Bacteria,1G2BD@1117|Cyanobacteria,1HJH8@1161|Nostocales	1117|Cyanobacteria	H	TIGRFAM bacteriochlorophyll chlorophyll synthetase	chlG	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	iJN678.chlG	UbiA
GGS1_k127_2090395_0	1118054.CAGW01000061_gene2406	9.127e-68	240.0	COG1024@1|root,COG1024@2|Bacteria,1TSII@1239|Firmicutes,4HA21@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GGS1_k127_2090395_5	1128421.JAGA01000002_gene1544	2.362e-18	98.0	COG2802@1|root,COG2802@2|Bacteria,2NPRK@2323|unclassified Bacteria	2|Bacteria	S	ATP-dependent protease La (LON) substrate-binding domain	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
GGS1_k127_2090395_1	1463903.JOIZ01000025_gene5744	3.065e-46	177.0	COG0847@1|root,COG0847@2|Bacteria,2GXVF@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051,RNase_T
GGS1_k127_2090395_2	237368.SCABRO_01729	3.943e-43	170.0	COG0518@1|root,COG0518@2|Bacteria,2J0QU@203682|Planctomycetes	203682|Planctomycetes	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
GGS1_k127_2090395_4	243365.CV_2920	1.526e-18	96.0	COG0596@1|root,COG0596@2|Bacteria,1R584@1224|Proteobacteria,2VUBF@28216|Betaproteobacteria,2KS5I@206351|Neisseriales	206351|Neisseriales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GGS1_k127_2090395_3	555088.DealDRAFT_0904	5.963e-25	113.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,42K0G@68298|Syntrophomonadaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GGS1_k127_2090395_6	1122925.KB895379_gene2335	3.793e-16	83.0	COG0492@1|root,COG0492@2|Bacteria,1UXYT@1239|Firmicutes,4HDB8@91061|Bacilli,26TIG@186822|Paenibacillaceae	91061|Bacilli	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GGS1_k127_2107558_1	1122138.AQUZ01000024_gene7742	7.101e-05	55.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4DS7Q@85009|Propionibacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GGS1_k127_2107558_0	429009.Adeg_1027	7.056e-36	152.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42J5R@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9
GGS1_k127_2111973_1	1408473.JHXO01000015_gene1906	1.259e-14	89.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GGS1_k127_2111973_0	1123228.AUIH01000092_gene552	1.56e-103	368.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2111973_2	439481.Aboo_1226	0.0006578	53.0	arCOG03256@1|root,arCOG03439@1|root,arCOG07760@1|root,arCOG03256@2157|Archaea,arCOG03439@2157|Archaea,arCOG07760@2157|Archaea,2Y704@28890|Euryarchaeota,3F320@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CUB,Peptidase_C25,Propeptide_C25
GGS1_k127_2134092_2	398767.Glov_2399	2.078e-79	274.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GGS1_k127_2134092_0	1187851.A33M_3197	3.384e-105	356.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
GGS1_k127_2134092_1	85643.Tmz1t_2951	2.811e-81	284.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
GGS1_k127_2134092_3	644282.Deba_2802	3.295e-10	63.0	COG0454@1|root,COG0456@2|Bacteria,1N5FD@1224|Proteobacteria,42U24@68525|delta/epsilon subdivisions,2WQXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_2148222_3	1121456.ATVA01000013_gene1000	3.012e-19	99.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,42PSS@68525|delta/epsilon subdivisions,2WKGZ@28221|Deltaproteobacteria,2MBKW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Mrr N-terminal domain	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	HARE-HTH,Mrr_N,Mrr_cat
GGS1_k127_2148222_0	1150399.AQYK01000001_gene163	5.565e-58	224.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,PKD
GGS1_k127_2148222_2	452637.Oter_0180	1.081e-33	148.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,3K7BD@414999|Opitutae	414999|Opitutae	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GGS1_k127_2148222_4	1122212.AULO01000008_gene1416	4.95e-09	66.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1XKS2@135619|Oceanospirillales	135619|Oceanospirillales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GGS1_k127_2148222_1	396588.Tgr7_3180	1.388e-55	208.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,1S2UN@1236|Gammaproteobacteria,1X11C@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GGS1_k127_2168014_2	1382304.JNIL01000001_gene2381	4.139e-104	357.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,27873@186823|Alicyclobacillaceae	91061|Bacilli	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GGS1_k127_2168014_1	1236689.MMALV_02050	3.143e-118	397.0	COG1008@1|root,arCOG01538@2157|Archaea	2157|Archaea	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.5.98.3,1.6.5.3	ko:K00342,ko:K22168	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Oxidored_q5_N,Proton_antipo_M
GGS1_k127_2168014_3	192952.MM_2480	2.88e-88	313.0	COG1007@1|root,arCOG01540@2157|Archaea,2XSY7@28890|Euryarchaeota,2N9SZ@224756|Methanomicrobia	224756|Methanomicrobia	C	Proton-conducting membrane transporter	-	-	1.5.98.3	ko:K22169	-	-	-	-	ko00000,ko01000	3.D.9.1	-	iAF692.Mbar_A3401	Proton_antipo_M
GGS1_k127_2168014_0	316274.Haur_4391	1.368e-124	411.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_2180287_0	1051632.TPY_1211	6.03e-24	115.0	COG0477@1|root,COG2814@2|Bacteria,1VP8C@1239|Firmicutes	1239|Firmicutes	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_2180287_2	1110502.TMO_1413	2.475e-08	65.0	COG0625@1|root,COG0625@2|Bacteria,1P71B@1224|Proteobacteria,2U1A5@28211|Alphaproteobacteria,2JV5M@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
GGS1_k127_2180287_1	365046.Rta_13040	5.176e-13	81.0	COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria	1224|Proteobacteria	DZ	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
GGS1_k127_2185880_2	997346.HMPREF9374_3504	5.402e-33	132.0	COG1112@1|root,COG2852@1|root,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli,27CB1@186824|Thermoactinomycetaceae	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
GGS1_k127_2185880_1	1089545.KB913037_gene230	1.382e-48	179.0	COG2128@1|root,COG2128@2|Bacteria,2IJCK@201174|Actinobacteria,4EER0@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GGS1_k127_2185880_3	694429.Pyrfu_0568	1.442e-05	55.0	COG1848@1|root,arCOG02221@2157|Archaea,2XSEY@28889|Crenarchaeota	28889|Crenarchaeota	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GGS1_k127_2185880_0	439481.Aboo_1130	1.155e-52	196.0	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,3F2H2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
GGS1_k127_219062_1	1045855.DSC_14200	1.704e-15	76.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales	135614|Xanthomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GGS1_k127_219062_0	1206101.AZXC01000001_gene4304	6.261e-86	310.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_219062_2	562743.JH976437_gene2418	1.204e-08	63.0	COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HHUZ@91061|Bacilli	91061|Bacilli	K	Transcriptional	ysmB	-	-	-	-	-	-	-	-	-	-	-	MarR
GGS1_k127_2217829_1	439481.Aboo_0952	2.869e-24	108.0	arCOG05517@1|root,arCOG05517@2157|Archaea,2Y72T@28890|Euryarchaeota,3F3AH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2217829_0	439481.Aboo_0489	1.943e-34	133.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GGS1_k127_2242044_0	985053.VMUT_1595	7.83e-16	92.0	COG0477@1|root,arCOG00130@2157|Archaea,2XRN4@28889|Crenarchaeota	28889|Crenarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_2242044_1	1236689.MMALV_12690	7.434e-06	53.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y1AH@28890|Euryarchaeota,3F2U9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	but it may be involved in stabilization of the trimeric complex	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
GGS1_k127_2248119_1	1449080.JQMV01000006_gene2272	8.661e-05	49.0	COG2929@1|root,COG2929@2|Bacteria,1WKTC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
GGS1_k127_2248119_0	580331.Thit_0906	6.397e-21	98.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,42EY9@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM UTP--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02205	NTP_transferase
GGS1_k127_2250456_0	1173029.JH980292_gene60	4.704e-21	99.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
GGS1_k127_2250456_1	673860.AciM339_0019	2.135e-06	62.0	COG0457@1|root,arCOG02493@1|root,arCOG02493@2157|Archaea,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	HTH_24,PQQ_2,PQQ_3,TPR_12,TPR_16,TPR_2,TPR_8
GGS1_k127_2255257_1	591158.SSMG_03494	4.502e-25	119.0	COG2244@1|root,COG2244@2|Bacteria,2GMYJ@201174|Actinobacteria	201174|Actinobacteria	G	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
GGS1_k127_2255257_2	1449069.JMLO01000005_gene1361	5.059e-13	80.0	COG1216@1|root,COG1216@2|Bacteria,2HH98@201174|Actinobacteria,4FVNU@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GGS1_k127_2255257_0	572546.Arcpr_0321	9.436e-58	211.0	COG0392@1|root,arCOG00897@2157|Archaea,2XT65@28890|Euryarchaeota,246JX@183980|Archaeoglobi	183980|Archaeoglobi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	Glycos_transf_2,LPG_synthase_TM
GGS1_k127_2266368_3	1141106.CAIB01000134_gene1149	1.391e-16	80.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HIKA@91061|Bacilli,4GZ46@90964|Staphylococcaceae	91061|Bacilli	S	Belongs to the HesB IscA family	erpA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GGS1_k127_2266368_2	1121949.AQXT01000002_gene1905	1.104e-25	121.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,43W7J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GGS1_k127_2266368_0	351160.RCIX1738	5.388e-125	411.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,2N95M@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	iAF692.Mbar_A3463	Aminotran_1_2
GGS1_k127_2266368_1	986075.CathTA2_2561	3.549e-30	122.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli	91061|Bacilli	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GGS1_k127_2269267_1	485913.Krac_8201	1.375e-12	72.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
GGS1_k127_2269267_0	345341.KUTG_05349	1.238e-39	153.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4E51X@85010|Pseudonocardiales	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GGS1_k127_2269267_2	1267535.KB906767_gene1989	3.74e-06	53.0	2DPS5@1|root,3335G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
GGS1_k127_2294380_2	1236689.MMALV_14250	1.052e-55	208.0	COG0469@1|root,arCOG04071@2157|Archaea,2XTXX@28890|Euryarchaeota,3F2K6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the polypeptide exit tunnel	rpl4	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GGS1_k127_2294380_0	439481.Aboo_1521	2.646e-106	356.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,3F2H1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GGS1_k127_2294380_1	1532557.JL37_02980	3.47e-60	212.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria,2W0C7@28216|Betaproteobacteria,3T7HI@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_2294380_4	1521187.JPIM01000023_gene799	2.404e-31	131.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_2294380_3	593750.Metfor_0196	3.727e-41	164.0	COG3276@1|root,arCOG01564@2157|Archaea,2XWBV@28890|Euryarchaeota,2N945@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM elongation factor Tu domain 2	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
GGS1_k127_2294380_5	178306.PAE2520	8.144e-22	98.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GGS1_k127_2299172_2	1236689.MMALV_16250	7.564e-36	158.0	COG0560@1|root,arCOG01158@2157|Archaea	2157|Archaea	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase,Hydrolase_3
GGS1_k127_2299172_0	192952.MM_0593	2.661e-158	508.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9HE@224756|Methanomicrobia	224756|Methanomicrobia	F	Protein of unknown function (DUF1246)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
GGS1_k127_2299172_1	1042877.GQS_10105	1.309e-37	161.0	COG2413@1|root,arCOG04066@2157|Archaea,2XSZH@28890|Euryarchaeota,24347@183968|Thermococci	183968|Thermococci	S	Nucleotidyltransferase domain	-	-	-	ko:K07073	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GGS1_k127_2299172_3	351160.RCIX285	2.866e-11	74.0	COG1658@1|root,arCOG01486@2157|Archaea,2Y0G2@28890|Euryarchaeota,2NA2F@224756|Methanomicrobia	224756|Methanomicrobia	L	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_4
GGS1_k127_2299172_5	69014.TK0768	2.284e-05	55.0	COG1872@1|root,arCOG04058@2157|Archaea,2XZV9@28890|Euryarchaeota,244II@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GGS1_k127_2299172_4	391589.RGAI101_496	1.823e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2P4QQ@2433|Roseobacter	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
GGS1_k127_2326321_0	909663.KI867150_gene2400	2.527e-74	264.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2MR7E@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GGS1_k127_232755_0	351160.RCIX132	1.917e-109	361.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2XYA0@28890|Euryarchaeota	28890|Euryarchaeota	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
GGS1_k127_232755_2	304371.MCP_2737	2.35e-34	150.0	arCOG05710@1|root,arCOG05710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_232755_1	374847.Kcr_0866	1.305e-84	297.0	COG1457@1|root,arCOG03447@2157|Archaea	2157|Archaea	F	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GGS1_k127_232755_3	797114.C475_20962	1.984e-11	66.0	COG1992@1|root,arCOG00021@2157|Archaea,2XTP7@28890|Euryarchaeota,23SNG@183963|Halobacteria	183963|Halobacteria	H	Transcriptional regulator	thiN2	-	-	ko:K22206	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,ThiP_synth
GGS1_k127_2331706_0	234267.Acid_2125	1.039e-34	143.0	COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,3Y878@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GGS1_k127_2342919_2	410358.Mlab_1051	3.273e-98	340.0	COG0076@1|root,arCOG00027@2157|Archaea	2157|Archaea	E	Belongs to the group II decarboxylase family. MfnA subfamily	-	-	4.1.1.86,4.1.2.48	ko:K01620,ko:K13745	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171,R07650	RC00299,RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
GGS1_k127_2342919_0	1128421.JAGA01000002_gene1751	6.428e-145	473.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
GGS1_k127_2342919_1	1128421.JAGA01000004_gene2611	1.71e-121	399.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GGS1_k127_235150_0	1034345.CAEM01000018_gene366	1.09e-47	181.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4CUQ7@84998|Coriobacteriia	84998|Coriobacteriia	IQ	Short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GGS1_k127_235150_1	572478.Vdis_1888	1.114e-36	149.0	COG0603@1|root,arCOG00039@2157|Archaea,2XRA3@28889|Crenarchaeota	28889|Crenarchaeota	H	biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GGS1_k127_2355583_0	644281.MFS40622_0392	5.438e-59	214.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,23Q49@183939|Methanococci	183939|Methanococci	J	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GGS1_k127_2355583_2	666509.RCA23_c26690	6.323e-15	85.0	COG0009@1|root,COG0009@2|Bacteria	2|Bacteria	J	L-threonylcarbamoyladenylate synthase	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GGS1_k127_2355583_1	693661.Arcve_0149	2.809e-32	134.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
GGS1_k127_2359618_1	66897.DJ64_02985	1.55e-10	67.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria	201174|Actinobacteria	H	PFAM thiamineS protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GGS1_k127_2359618_0	861299.J421_0666	4.018e-92	316.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2361039_1	673860.AciM339_0905	3.531e-12	72.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GGS1_k127_2361039_0	439481.Aboo_0964	1.502e-127	419.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F31W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GGS1_k127_236496_1	589865.DaAHT2_1112	1.644e-42	164.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
GGS1_k127_236496_0	1121468.AUBR01000064_gene947	3.131e-290	905.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GGS1_k127_2370823_2	579137.Metvu_0718	2.529e-27	119.0	COG1908@1|root,arCOG02475@2157|Archaea,2XY1E@28890|Euryarchaeota,23QTP@183939|Methanococci	183939|Methanococci	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
GGS1_k127_2370823_3	1125863.JAFN01000001_gene2643	2.951e-22	104.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
GGS1_k127_2370823_4	195522.BD01_0452	4.869e-22	104.0	COG2178@1|root,arCOG04318@2157|Archaea,2XYD0@28890|Euryarchaeota,242PY@183968|Thermococci	183968|Thermococci	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
GGS1_k127_2370823_0	645991.Sgly_0856	3.039e-70	256.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
GGS1_k127_2370823_5	673860.AciM339_1211	3.203e-10	70.0	COG1361@1|root,arCOG02079@2157|Archaea,2Y6ZQ@28890|Euryarchaeota,3F30V@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2370823_7	673860.AciM339_1211	0.0001219	55.0	COG1361@1|root,arCOG02079@2157|Archaea,2Y6ZQ@28890|Euryarchaeota,3F30V@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2370823_1	192952.MM_3150	1.178e-54	215.0	COG2520@1|root,arCOG10124@2157|Archaea,2XTPV@28890|Euryarchaeota,2N953@224756|Methanomicrobia	224756|Methanomicrobia	J	S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe)	taw2	-	2.5.1.114	ko:K07055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Met_10
GGS1_k127_2370823_6	8469.XP_007060447.1	7.569e-06	57.0	28IWW@1|root,2QR8M@2759|Eukaryota,38G0N@33154|Opisthokonta,3BCJK@33208|Metazoa,3CUA0@33213|Bilateria,4879X@7711|Chordata,48XBD@7742|Vertebrata,4CH5Z@8459|Testudines	33208|Metazoa	S	REJ domain	KIAA0319	GO:0001764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0006928,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010721,GO:0010975,GO:0010977,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016477,GO:0022008,GO:0030135,GO:0030136,GO:0030154,GO:0030659,GO:0030662,GO:0030665,GO:0031090,GO:0031344,GO:0031345,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0040011,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0048519,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051129,GO:0051179,GO:0051239,GO:0051241,GO:0051674,GO:0051960,GO:0051961,GO:0060284,GO:0061024,GO:0065007,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098805,GO:0120035,GO:2000026,GO:2000171	-	-	-	-	-	-	-	-	-	-	REJ
GGS1_k127_2373907_0	673860.AciM339_0619	3.654e-62	217.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,3F2HE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Intein_splicing,Rad51
GGS1_k127_2373907_4	1227457.C451_14650	1.948e-06	58.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XWJ8@28890|Euryarchaeota,23VFA@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_10
GGS1_k127_2373907_6	932213.SPM24T3_21884	7.461e-05	51.0	COG0662@1|root,COG0662@2|Bacteria,1RE65@1224|Proteobacteria,1S5FG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GGS1_k127_2373907_3	304371.MCP_2430	1.295e-14	85.0	COG1575@1|root,arCOG00480@2157|Archaea,2Y7CB@28890|Euryarchaeota,2NBFB@224756|Methanomicrobia	224756|Methanomicrobia	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GGS1_k127_2373907_5	398578.Daci_4515	3.694e-05	58.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
GGS1_k127_2373907_1	439481.Aboo_1186	6.418e-52	200.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,3F2NQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
GGS1_k127_2373907_2	673860.AciM339_0837	1.003e-39	161.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,3F2RT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	PFAM tRNA methyltransferase complex GCD14 subunit	trmI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031515,GO:0032991,GO:0034708,GO:0043527,GO:0044424,GO:0044444,GO:0044464,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
GGS1_k127_2375805_9	1123253.AUBD01000013_gene940	0.0004357	50.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,1S3KC@1236|Gammaproteobacteria,1X5GB@135614|Xanthomonadales	135614|Xanthomonadales	K	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,NTP_transf_2
GGS1_k127_2375805_2	1094980.Mpsy_0469	5.198e-33	147.0	COG2018@1|root,arCOG02603@2157|Archaea	2157|Archaea	T	Roadblock LC7 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2375805_0	1094980.Mpsy_0470	2.421e-98	329.0	COG0467@1|root,arCOG01171@2157|Archaea,2XYM8@28890|Euryarchaeota,2NAU4@224756|Methanomicrobia	224756|Methanomicrobia	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_2375805_7	178306.PAE3658	4.095e-08	60.0	arCOG03723@1|root,arCOG03723@2157|Archaea,2XS44@28889|Crenarchaeota	28889|Crenarchaeota	S	Archaeal PaREP1/PaREP8 family	-	-	-	-	-	-	-	-	-	-	-	-	PaREP1
GGS1_k127_2375805_6	1348663.KCH_39790	1.385e-08	66.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,2M0C5@2063|Kitasatospora	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
GGS1_k127_2375805_5	929556.Solca_1350	7.539e-10	64.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GGS1_k127_2375805_1	1054217.TALC_00210	7.153e-48	184.0	COG0377@1|root,arCOG01554@2157|Archaea,2XTP1@28890|Euryarchaeota,241SV@183967|Thermoplasmata	183967|Thermoplasmata	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.5.98.3,1.6.5.3	ko:K00331,ko:K22159	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Oxidored_q6
GGS1_k127_2375805_3	1118054.CAGW01000043_gene1145	1.941e-26	117.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,26RPJ@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GGS1_k127_2375805_4	903818.KI912268_gene3069	3.898e-12	76.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GGS1_k127_2378519_0	1459636.NTE_00007	1.096e-85	308.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
GGS1_k127_2378519_3	349521.HCH_05528	3.341e-10	72.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1SBXR@1236|Gammaproteobacteria,1XMF8@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GGS1_k127_2378519_2	1242864.D187_009111	2.885e-15	89.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,42RQJ@68525|delta/epsilon subdivisions,2WNW8@28221|Deltaproteobacteria,2YVCK@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GGS1_k127_2378519_1	760192.Halhy_0025	2.865e-56	202.0	COG2128@1|root,COG2128@2|Bacteria,4NNYF@976|Bacteroidetes,1IT75@117747|Sphingobacteriia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GGS1_k127_2388031_0	673860.AciM339_1192	7.424e-13	81.0	arCOG03853@1|root,arCOG03853@2157|Archaea,2Y52X@28890|Euryarchaeota,3F32T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2399234_0	1353529.M899_2277	7.771e-16	93.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
GGS1_k127_240424_0	883169.HMPREF9719_00436	0.0003196	46.0	COG0640@1|root,COG0640@2|Bacteria,2IMSD@201174|Actinobacteria,22P6P@1653|Corynebacteriaceae	201174|Actinobacteria	K	transcriptional	smtB	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GGS1_k127_2408399_0	8479.XP_008173959.1	1.633e-54	217.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4837Y@7711|Chordata,497BW@7742|Vertebrata,4CIFV@8459|Testudines	33208|Metazoa	W	Inter-alpha-trypsin inhibitor heavy chain	ITIH6	-	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA,VWA_3
GGS1_k127_2432311_0	1236689.MMALV_03530	2.299e-70	251.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,3F2KY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Fer4,RNA_pol_A_bac,RNA_pol_L
GGS1_k127_2432311_1	565033.GACE_0208	2.642e-58	204.0	COG0100@1|root,arCOG04240@2157|Archaea,2XX1S@28890|Euryarchaeota,24666@183980|Archaeoglobi	183980|Archaeoglobi	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GGS1_k127_2432311_2	673860.AciM339_1559	5.813e-52	193.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,3F2KM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GGS1_k127_2432311_3	1054217.TALC_00426	1.515e-39	156.0	COG0099@1|root,arCOG01722@2157|Archaea,2XWHE@28890|Euryarchaeota,241SD@183967|Thermoplasmata	183967|Thermoplasmata	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GGS1_k127_2434348_0	287986.DV20_28205	3.442e-49	185.0	COG1647@1|root,COG1647@2|Bacteria,2I5E3@201174|Actinobacteria,4EDWG@85010|Pseudonocardiales	201174|Actinobacteria	S	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GGS1_k127_2434348_1	456442.Mboo_0936	3.245e-15	89.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3920@1|root,arCOG06712@1|root,arCOG02335@2157|Archaea,arCOG02357@2157|Archaea,arCOG06192@2157|Archaea,arCOG06712@2157|Archaea,arCOG06918@2157|Archaea,2Y7UU@28890|Euryarchaeota,2NANW@224756|Methanomicrobia	224756|Methanomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS_9
GGS1_k127_2453805_0	886293.Sinac_1689	4.81e-193	613.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GGS1_k127_2465835_3	439481.Aboo_1237	5.018e-16	78.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,3F2S8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
GGS1_k127_2465835_2	565033.GACE_1329	1.206e-22	98.0	COG2075@1|root,arCOG01950@2157|Archaea,2Y00Q@28890|Euryarchaeota,246HX@183980|Archaeoglobi	183980|Archaeoglobi	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
GGS1_k127_2465835_1	1194526.A284_06335	1.623e-50	183.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,4GYXP@90964|Staphylococcaceae	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GGS1_k127_2465835_0	439481.Aboo_0942	3.48e-126	414.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
GGS1_k127_2466364_1	877455.Metbo_0697	3.27e-68	259.0	COG0842@1|root,arCOG01463@2157|Archaea,2Y34U@28890|Euryarchaeota,23PDD@183925|Methanobacteria	183925|Methanobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GGS1_k127_2466364_0	868131.MSWAN_1558	3.662e-92	314.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,23PFF@183925|Methanobacteria	183925|Methanobacteria	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_2466364_2	938289.CAJN020000001_gene1125	1.925e-62	228.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
GGS1_k127_2467925_2	694429.Pyrfu_0407	4.44e-12	68.0	COG1656@1|root,arCOG04290@2157|Archaea,2XQD5@28889|Crenarchaeota	28889|Crenarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
GGS1_k127_2467925_1	1455608.JDTH01000002_gene559	4.83e-43	165.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,23S8U@183963|Halobacteria	183963|Halobacteria	H	COG1985 Pyrimidine reductase, riboflavin biosynthesis	ribG	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
GGS1_k127_2467925_0	673860.AciM339_0285	1.237e-68	243.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
GGS1_k127_2467925_3	388413.ALPR1_21088	2.153e-10	76.0	COG1361@1|root,COG3210@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11
GGS1_k127_2474439_3	1179773.BN6_56380	5.686e-06	58.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4EF8A@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
GGS1_k127_2474439_2	572546.Arcpr_0279	6.141e-25	113.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,246B1@183980|Archaeoglobi	183980|Archaeoglobi	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
GGS1_k127_2474439_0	1132509.C447_06903	2.01e-34	145.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,23V82@183963|Halobacteria	183963|Halobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
GGS1_k127_2474439_1	926550.CLDAP_28350	3.156e-29	136.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
GGS1_k127_2475103_6	1249997.JHZW01000003_gene2150	1.996e-05	51.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4PI47@976|Bacteroidetes,1IM97@117743|Flavobacteriia,2PI57@252356|Maribacter	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
GGS1_k127_2475103_0	673860.AciM339_0523	4.592e-83	283.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GGS1_k127_2475103_3	523845.AQXV01000048_gene623	6.21e-17	93.0	COG0618@1|root,arCOG01565@2157|Archaea,2XWQV@28890|Euryarchaeota,23Q6X@183939|Methanococci	183939|Methanococci	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
GGS1_k127_2475103_4	272569.rrnAC1680	1.32e-11	73.0	COG1382@1|root,arCOG01342@2157|Archaea,2XX88@28890|Euryarchaeota,23VTW@183963|Halobacteria	183963|Halobacteria	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
GGS1_k127_2475103_5	1054217.TALC_00324	1.971e-06	57.0	COG1996@1|root,arCOG04341@2157|Archaea,2Y5VN@28890|Euryarchaeota	28890|Euryarchaeota	K	DNA directed RNA polymerase, 7 kDa subunit	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
GGS1_k127_2475103_2	1236689.MMALV_02960	2.394e-19	91.0	COG1997@1|root,arCOG04208@2157|Archaea,2Y6HQ@28890|Euryarchaeota,3F2TK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
GGS1_k127_2475103_1	439481.Aboo_0181	2.111e-32	130.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,3F2JS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
GGS1_k127_2486757_2	1094980.Mpsy_2215	9.957e-23	105.0	COG4800@1|root,arCOG04375@2157|Archaea,2XXJS@28890|Euryarchaeota,2N9MB@224756|Methanomicrobia	224756|Methanomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GGS1_k127_2486757_1	1408254.T458_07345	4.363e-29	131.0	COG1413@1|root,COG1413@2|Bacteria,1VQHH@1239|Firmicutes,4HR74@91061|Bacilli,2735B@186822|Paenibacillaceae	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2486757_0	1448860.BBJO01000037_gene3306	2.168e-69	243.0	COG1028@1|root,arCOG01259@2157|Archaea,2XVG3@28890|Euryarchaeota,23SCN@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GGS1_k127_2486757_3	1121479.AUBS01000002_gene3633	6.819e-11	75.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_2500627_2	351160.LRC318	4.541e-38	160.0	COG2202@1|root,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9,Response_reg
GGS1_k127_2500627_1	247490.KSU1_C0935	3.204e-47	178.0	COG0450@1|root,COG0450@2|Bacteria,2IZ3M@203682|Planctomycetes	203682|Planctomycetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
GGS1_k127_2500627_0	555088.DealDRAFT_3034	1.86e-60	215.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,25MYX@186801|Clostridia,42KTR@68298|Syntrophomonadaceae	186801|Clostridia	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GGS1_k127_2504189_0	880073.Calab_0491	8.463e-52	188.0	COG1881@1|root,COG1881@2|Bacteria,2NPDK@2323|unclassified Bacteria	2|Bacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GGS1_k127_2520410_0	589865.DaAHT2_1404	2.839e-65	234.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,42RKK@68525|delta/epsilon subdivisions,2WNV3@28221|Deltaproteobacteria,2MK5P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
GGS1_k127_2520410_1	1041930.Mtc_0203	2.489e-07	60.0	COG0438@1|root,arCOG01410@2157|Archaea,2Y8BT@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_2520643_2	1198232.CYCME_2140	1.084e-05	52.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V9@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
GGS1_k127_2520643_1	555079.Toce_1728	1.848e-36	153.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,42FN8@68295|Thermoanaerobacterales	186801|Clostridia	M	1,4-dihydroxy-2-naphthoate octaprenyltransferase	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GGS1_k127_2520643_0	1200792.AKYF01000018_gene5736	8.721e-74	265.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,26UV4@186822|Paenibacillaceae	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
GGS1_k127_2522147_0	1236689.MMALV_09120	2.315e-73	270.0	COG4962@1|root,arCOG01818@2157|Archaea,2Y8F6@28890|Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GGS1_k127_2522598_0	1379698.RBG1_1C00001G1377	2.501e-43	177.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
GGS1_k127_2522598_1	644966.Tmar_0113	1.314e-27	115.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WCNM@538999|Clostridiales incertae sedis	186801|Clostridia	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GGS1_k127_2527348_0	1054217.TALC_01077	6.113e-131	436.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,241J5@183967|Thermoplasmata	183967|Thermoplasmata	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
GGS1_k127_252962_1	694440.JOMF01000004_gene1318	4.78e-09	62.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,2N966@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GGS1_k127_252962_0	644281.MFS40622_1481	2.908e-34	148.0	COG0513@1|root,arCOG00078@2157|Archaea,2XTFM@28890|Euryarchaeota,23QPI@183939|Methanococci	183939|Methanococci	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
GGS1_k127_2539792_1	410358.Mlab_1119	4.666e-49	187.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2N9P3@224756|Methanomicrobia	224756|Methanomicrobia	K	Phosphate uptake regulator, PhoU	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
GGS1_k127_2539792_4	1158601.I585_01094	1.512e-09	66.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,4B3P6@81852|Enterococcaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	czrA	-	-	ko:K22043	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GGS1_k127_2539792_0	1041930.Mtc_0963	2.307e-114	379.0	COG0798@1|root,arCOG02190@2157|Archaea,2XTQC@28890|Euryarchaeota,2N935@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
GGS1_k127_2539792_3	591167.Sfla_6186	8.741e-36	141.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GGS1_k127_2539792_2	1459636.NTE_01319	1.233e-37	151.0	arCOG00517@1|root,arCOG00517@2157|Archaea	2157|Archaea	P	COG0607 Rhodanese-related sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
GGS1_k127_2544749_2	1094980.Mpsy_0730	4.091e-30	136.0	COG3291@1|root,COG3420@1|root,COG3979@1|root,arCOG02508@2157|Archaea,arCOG02519@2157|Archaea,arCOG02546@2157|Archaea,arCOG07581@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_2544749_1	1054217.TALC_01532	3.171e-31	130.0	COG4860@1|root,arCOG04366@2157|Archaea,2XYAX@28890|Euryarchaeota,241R5@183967|Thermoplasmata	183967|Thermoplasmata	K	ArsR transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ArsR
GGS1_k127_2544749_0	272844.PAB1040	1.704e-48	179.0	COG1303@1|root,arCOG01857@2157|Archaea,2XV35@28890|Euryarchaeota,242JJ@183968|Thermococci	183968|Thermococci	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
GGS1_k127_2551136_3	1229909.NSED_05495	1.117e-09	68.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2551136_2	1459636.NTE_03027	1.709e-14	82.0	arCOG08805@1|root,arCOG08805@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2551136_1	1449357.JQLK01000001_gene1667	2.552e-34	152.0	2A1UA@1|root,30Q39@2|Bacteria,1WM6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2551136_4	113355.CM001775_gene1664	9.539e-08	65.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
GGS1_k127_2551136_0	1123242.JH636435_gene2634	3.067e-80	279.0	COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GGS1_k127_2557216_0	420662.Mpe_A2383	1.297e-32	138.0	COG0863@1|root,COG0863@2|Bacteria,1R832@1224|Proteobacteria,2VRY1@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GGS1_k127_2557216_1	871968.DESME_00855	9.931e-08	59.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,262BX@186807|Peptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GGS1_k127_2570178_1	290397.Adeh_0259	5.272e-29	121.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YUA4@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GGS1_k127_2570178_0	580340.Tlie_1075	6.742e-48	182.0	COG2109@1|root,COG2109@2|Bacteria,3TB75@508458|Synergistetes	508458|Synergistetes	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
GGS1_k127_2570178_2	330214.NIDE3941	9.842e-12	79.0	COG2202@1|root,COG3290@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,3J124@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GGS1_k127_2572017_1	1333523.L593_11780	3.529e-42	165.0	COG1277@1|root,arCOG02440@2157|Archaea,2XX79@28890|Euryarchaeota,23TG0@183963|Halobacteria	183963|Halobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
GGS1_k127_2572017_0	203124.Tery_3996	6.051e-215	724.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8
GGS1_k127_2574010_1	1173024.KI912149_gene6330	6.238e-21	94.0	2ESTF@1|root,33KBV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2574010_0	323261.Noc_1844	8.189e-124	402.0	COG0265@1|root,COG0265@2|Bacteria,1R6VW@1224|Proteobacteria,1SNEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2580010_0	765420.OSCT_0450	2.233e-79	274.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GGS1_k127_258346_1	647113.Metok_0013	1.354e-16	83.0	COG1698@1|root,arCOG04308@2157|Archaea,2XZVX@28890|Euryarchaeota,23R51@183939|Methanococci	183939|Methanococci	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
GGS1_k127_258346_0	883.DvMF_2133	4.81e-26	125.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2M873@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
GGS1_k127_258346_2	868131.MSWAN_0477	2.003e-06	55.0	COG1714@1|root,arCOG03633@2157|Archaea,2Y140@28890|Euryarchaeota,23P6J@183925|Methanobacteria	183925|Methanobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GGS1_k127_258896_5	443906.CMM_0825	1.417e-24	118.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
GGS1_k127_258896_2	1121422.AUMW01000005_gene654	5.885e-90	310.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GGS1_k127_258896_1	643648.Slip_0851	3.631e-103	349.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42KH0@68298|Syntrophomonadaceae	186801|Clostridia	H	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GGS1_k127_258896_4	760568.Desku_1300	2.235e-76	266.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GGS1_k127_258896_0	420247.Msm_1371	6.741e-109	367.0	COG0019@1|root,arCOG02268@2157|Archaea,2XSY8@28890|Euryarchaeota,23NJI@183925|Methanobacteria	183925|Methanobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GGS1_k127_258896_3	243232.MJ_0571	1.444e-87	306.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,23QME@183939|Methanococci	183939|Methanococci	E	Belongs to the aspartokinase family	-	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
GGS1_k127_258896_6	1094980.Mpsy_1399	5.603e-24	103.0	COG0289@1|root,arCOG04393@2157|Archaea,2XTJU@28890|Euryarchaeota,2N9BV@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GGS1_k127_2589503_4	42256.RradSPS_0018	5.48e-07	58.0	COG1714@1|root,COG1714@2|Bacteria,2HP4S@201174|Actinobacteria,4CQGE@84995|Rubrobacteria	84995|Rubrobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GGS1_k127_2589503_0	1382356.JQMP01000003_gene1858	5.434e-100	340.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GGS1_k127_2589503_1	273116.14324489	5.831e-98	332.0	COG0045@1|root,arCOG01337@2157|Archaea,2XTSC@28890|Euryarchaeota,24256@183967|Thermoplasmata	183967|Thermoplasmata	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GGS1_k127_2589503_3	1131266.ARWQ01000005_gene818	4.365e-07	57.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
GGS1_k127_2589503_2	263820.PTO1429	8.082e-31	134.0	COG0350@1|root,COG1515@1|root,arCOG00929@2157|Archaea,arCOG02724@2157|Archaea,2XURE@28890|Euryarchaeota,24279@183967|Thermoplasmata	183967|Thermoplasmata	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Endonuclease_5
GGS1_k127_2590095_0	351160.RCIX823	1.35e-79	292.0	COG2409@1|root,arCOG02175@2157|Archaea,2XVKJ@28890|Euryarchaeota	28890|Euryarchaeota	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GGS1_k127_2590095_1	570952.ATVH01000013_gene3125	0.0004432	53.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2JS1T@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_16,TPR_19,TPR_8
GGS1_k127_2603643_5	269796.Rru_A0322	5.312e-09	65.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,2UMM4@28211|Alphaproteobacteria,2JY79@204441|Rhodospirillales	204441|Rhodospirillales	C	Hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
GGS1_k127_2603643_1	439481.Aboo_0301	3.706e-104	348.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GGS1_k127_2603643_0	439481.Aboo_0300	3.448e-113	383.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,3F36A@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.1,1.2.7.7	ko:K00169,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GGS1_k127_2603643_4	246969.TAM4_1406	4.222e-20	103.0	COG1144@1|root,arCOG01605@2157|Archaea,2Y02N@28890|Euryarchaeota,244AY@183968|Thermococci	183968|Thermococci	C	4Fe-4S dicluster domain	vorD	-	1.2.7.7	ko:K00188	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
GGS1_k127_2603643_3	1125863.JAFN01000001_gene2836	9.94e-51	196.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GGS1_k127_2603643_2	397948.Cmaq_1860	2.942e-51	187.0	COG1013@1|root,arCOG01601@2157|Archaea,2XPQR@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GGS1_k127_2604974_0	368408.Tpen_1406	0.0004761	48.0	arCOG09752@1|root,arCOG09752@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2613002_1	593750.Metfor_0144	8.749e-36	139.0	COG3261@1|root,arCOG01547@2157|Archaea,2Y7K6@28890|Euryarchaeota,2N9MK@224756|Methanomicrobia	224756|Methanomicrobia	C	Membrane bound hydrogenase subunit	-	-	1.12.7.2	ko:K18016	-	-	R00019	-	ko00000,ko01000	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
GGS1_k127_2613002_0	593750.Metfor_0143	6.945e-104	347.0	COG1005@1|root,arCOG01546@2157|Archaea,2XT7N@28890|Euryarchaeota,2N9XC@224756|Methanomicrobia	224756|Methanomicrobia	C	Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	fpoH	-	1.5.98.3,1.6.5.3	ko:K00337,ko:K22163	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	NADHdh
GGS1_k127_2613002_2	593750.Metfor_0142	2.538e-22	104.0	COG1143@1|root,arCOG01543@2157|Archaea	2157|Archaea	C	Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I)	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GGS1_k127_2616986_0	1459636.NTE_02649	1.38e-220	691.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GGS1_k127_2616986_1	525904.Tter_1699	1.683e-71	246.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GGS1_k127_2631010_9	1229172.JQFA01000004_gene702	5.166e-24	109.0	COG1670@1|root,COG1670@2|Bacteria,1GA76@1117|Cyanobacteria,1HGA7@1150|Oscillatoriales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GGS1_k127_2631010_12	595537.Varpa_5120	1.515e-10	76.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,1R14N@1224|Proteobacteria,2WHZ9@28216|Betaproteobacteria,4AIB3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2631010_11	1121918.ARWE01000001_gene512	2.452e-12	82.0	COG3291@1|root,COG5263@1|root,COG3291@2|Bacteria,COG5263@2|Bacteria,1RA9Y@1224|Proteobacteria	1224|Proteobacteria	DZ	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
GGS1_k127_2631010_8	339670.Bamb_4289	2.101e-45	178.0	COG0460@1|root,COG0460@2|Bacteria,1R6I3@1224|Proteobacteria,2W0JJ@28216|Betaproteobacteria,1K9NE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh
GGS1_k127_2631010_3	290397.Adeh_3707	3.363e-118	396.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GGS1_k127_2631010_7	1304880.JAGB01000004_gene1484	7.458e-50	188.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GGS1_k127_2631010_2	1121472.AQWN01000001_gene274	2.025e-119	399.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GGS1_k127_2631010_5	644281.MFS40622_0827	5.786e-99	340.0	COG0119@1|root,arCOG02092@2157|Archaea,2XSZJ@28890|Euryarchaeota,23QBT@183939|Methanococci	183939|Methanococci	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GGS1_k127_2631010_1	1121468.AUBR01000019_gene2618	9.742e-122	400.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,42F2M@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GGS1_k127_2631010_4	1449126.JQKL01000030_gene2486	3.684e-105	356.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,267WZ@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
GGS1_k127_2631010_6	243231.GSU0150	3.835e-66	237.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,43UK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GGS1_k127_2631010_0	396588.Tgr7_2464	9.317e-128	421.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GGS1_k127_2631010_10	1054217.TALC_00633	2.762e-21	96.0	arCOG01806@1|root,arCOG01806@2157|Archaea,2Y0PI@28890|Euryarchaeota,242EI@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2639478_0	1236689.MMALV_16740	1.021e-50	196.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2IQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DEAD/H associated	lhr2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GGS1_k127_2639478_1	1249627.D779_3099	1.245e-16	92.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1RNS3@1236|Gammaproteobacteria,1WY2Y@135613|Chromatiales	135613|Chromatiales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GGS1_k127_2640303_0	1408473.JHXO01000015_gene1906	1.364e-21	111.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GGS1_k127_2640303_1	589924.Ferp_0541	1.842e-09	70.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
GGS1_k127_2646805_4	28444.JODQ01000005_gene1573	8.529e-05	48.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria,4EJDK@85012|Streptosporangiales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
GGS1_k127_2646805_1	1121422.AUMW01000001_gene2364	5.285e-31	126.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,261XA@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GGS1_k127_2646805_2	246969.TAM4_1512	3.974e-24	106.0	COG0784@1|root,arCOG02391@2157|Archaea,2XXBY@28890|Euryarchaeota,2449F@183968|Thermococci	183968|Thermococci	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GGS1_k127_2646805_3	673860.AciM339_0498	7.44e-17	85.0	COG4738@1|root,arCOG04377@2157|Archaea,2XZEC@28890|Euryarchaeota,3F3DI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2646805_0	525904.Tter_1457	5.797e-62	226.0	COG0120@1|root,COG0120@2|Bacteria,2NPMQ@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.7.1.12,2.7.1.15,5.3.1.6	ko:K00851,ko:K00852,ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01051,R01056,R01737,R02750	RC00002,RC00017,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
GGS1_k127_2647994_1	439481.Aboo_1506	1.404e-47	174.0	COG0096@1|root,arCOG04091@2157|Archaea,2XWMU@28890|Euryarchaeota,3F2NR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
GGS1_k127_2647994_0	439481.Aboo_1505	8.372e-51	185.0	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,3F2ND@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GGS1_k127_2647994_2	1054217.TALC_01317	6.579e-38	152.0	COG1717@1|root,arCOG00781@2157|Archaea,2XSZ4@28890|Euryarchaeota,241T4@183967|Thermoplasmata	183967|Thermoplasmata	J	structural constituent of ribosome	rpl32e	-	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
GGS1_k127_2647994_3	1094980.Mpsy_1128	1.65e-08	65.0	COG2147@1|root,arCOG04089@2157|Archaea,2XWU1@28890|Euryarchaeota,2N9QQ@224756|Methanomicrobia	224756|Methanomicrobia	J	binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
GGS1_k127_2652293_0	1177179.A11A3_06958	5.924e-26	126.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2656015_0	439481.Aboo_0405	3.6e-249	781.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
GGS1_k127_2656015_3	932678.THERU_00520	1.163e-10	71.0	COG1913@1|root,COG1913@2|Bacteria,2G48Z@200783|Aquificae	200783|Aquificae	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
GGS1_k127_2656015_2	1347086.CCBA010000023_gene2064	1.504e-15	87.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bprF	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
GGS1_k127_2656015_1	673860.AciM339_0339	1.444e-36	147.0	COG1779@1|root,arCOG04265@2157|Archaea,2XWNA@28890|Euryarchaeota,3F35K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	ZPR1-related zinc finger protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K06874	-	-	-	-	ko00000	-	-	-	zf-ZPR1
GGS1_k127_2657361_5	215803.DB30_1995	8.773e-06	59.0	COG2931@1|root,COG4409@1|root,COG2931@2|Bacteria,COG4409@2|Bacteria,1MU7T@1224|Proteobacteria,42R1I@68525|delta/epsilon subdivisions,2WMVI@28221|Deltaproteobacteria,2YTYV@29|Myxococcales	28221|Deltaproteobacteria	GQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4215
GGS1_k127_2657361_4	1226994.AMZB01000117_gene2636	1.196e-06	63.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1YE9I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,HemolysinCabind,PA14
GGS1_k127_2657361_1	401526.TcarDRAFT_1426	4.504e-17	95.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4H557@909932|Negativicutes	909932|Negativicutes	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GGS1_k127_2657361_3	316067.Geob_1157	4.488e-11	68.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GGS1_k127_2657361_2	436308.Nmar_0233	5.588e-13	74.0	COG3324@1|root,arCOG04946@2157|Archaea,41T3T@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
GGS1_k127_2657361_0	272557.APE_1044	6.198e-33	134.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQJA@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
GGS1_k127_2666548_3	1070774.J07HN4v3_00095	7.905e-05	55.0	arCOG07655@1|root,arCOG07655@2157|Archaea,2Y71F@28890|Euryarchaeota,23UID@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2666548_1	604354.TSIB_1787	1.987e-42	167.0	COG2102@1|root,arCOG00035@2157|Archaea,2XTNJ@28890|Euryarchaeota,242TE@183968|Thermococci	183968|Thermococci	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
GGS1_k127_2666548_0	439481.Aboo_0635	1.555e-94	325.0	COG0112@1|root,arCOG00070@2157|Archaea,2XX80@28890|Euryarchaeota,3F334@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Serine hydroxymethyltransferase	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GGS1_k127_2666548_2	192952.MM_1879	5.238e-28	119.0	COG1096@1|root,arCOG00676@2157|Archaea,2XYYA@28890|Euryarchaeota,2N9T0@224756|Methanomicrobia	224756|Methanomicrobia	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,EXOSC1
GGS1_k127_2667020_2	573064.Mefer_0808	1.086e-23	106.0	COG1594@1|root,arCOG00579@2157|Archaea,2XY3E@28890|Euryarchaeota,23R2W@183939|Methanococci	183939|Methanococci	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
GGS1_k127_2667020_1	243232.MJ_1148	2.205e-24	106.0	COG1594@1|root,arCOG00579@2157|Archaea,2XY3E@28890|Euryarchaeota,23R2W@183939|Methanococci	183939|Methanococci	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
GGS1_k127_2667020_0	1073999.BN137_598	1.1e-85	296.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GGS1_k127_2669885_1	1379698.RBG1_1C00001G0906	1.489e-57	209.0	COG1028@1|root,COG1028@2|Bacteria,2NP35@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GGS1_k127_2669885_0	1054217.TALC_00152	5.338e-88	312.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,241Q4@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GGS1_k127_2684213_1	1463887.KL589989_gene2186	1.301e-55	199.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
GGS1_k127_2684213_0	1121946.AUAX01000021_gene8088	1.276e-116	386.0	COG0473@1|root,COG0473@2|Bacteria,2I8V7@201174|Actinobacteria	201174|Actinobacteria	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GGS1_k127_2684213_2	349520.PPE_01411	9.08e-36	157.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HC99@91061|Bacilli,26T68@186822|Paenibacillaceae	91061|Bacilli	P	Kef-type K transport systems, membrane components	yhaU	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
GGS1_k127_2684844_1	439481.Aboo_1099	1.499e-23	113.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,3F2S6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	TIGRFAM segregation and condensation protein B	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GGS1_k127_2684844_0	797209.ZOD2009_19678	1.071e-45	178.0	COG0013@1|root,arCOG01254@2157|Archaea,2XTZC@28890|Euryarchaeota,23UTP@183963|Halobacteria	183963|Halobacteria	J	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
GGS1_k127_2684844_2	1298880.AUEV01000003_gene3414	9.751e-14	73.0	COG2271@1|root,COG2271@2|Bacteria,2I8XD@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GGS1_k127_2690200_1	192952.MM_0690	7.223e-15	80.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,2N9GP@224756|Methanomicrobia	224756|Methanomicrobia	J	pfam nmd3	-	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
GGS1_k127_2690200_2	1236689.MMALV_16790	8.009e-14	76.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,3F2V4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
GGS1_k127_2690200_0	1094980.Mpsy_0933	1.134e-136	448.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,2N9E6@224756|Methanomicrobia	224756|Methanomicrobia	L	Belongs to the MCM family	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
GGS1_k127_2699985_1	1236689.MMALV_02630	1.121e-34	138.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,3F2GI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Amidohydrolase family	dadD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GGS1_k127_2699985_0	1054217.TALC_00076	3.323e-142	464.0	COG0499@1|root,arCOG04137@2157|Archaea,2XT4S@28890|Euryarchaeota,241J8@183967|Thermoplasmata	183967|Thermoplasmata	F	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GGS1_k127_2699985_2	1054217.TALC_00049	1.277e-06	58.0	COG0524@1|root,arCOG00014@2157|Archaea,2Y65P@28890|Euryarchaeota,241U0@183967|Thermoplasmata	183967|Thermoplasmata	F	pfkB family carbohydrate kinase	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108	2.7.1.213,2.7.1.73	ko:K22026	ko00230,ko00240,map00230,map00240	-	R00513,R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GGS1_k127_2711264_2	477974.Daud_2184	1.623e-30	129.0	COG0863@1|root,COG0863@2|Bacteria,1TPR7@1239|Firmicutes,24A3P@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GGS1_k127_2711264_1	269797.Mbar_A0140	3.291e-47	179.0	COG0639@1|root,arCOG01143@2157|Archaea,2XUDG@28890|Euryarchaeota,2NAJW@224756|Methanomicrobia	224756|Methanomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,Metallophos_2
GGS1_k127_2711264_3	404589.Anae109_1519	6.424e-14	77.0	COG5652@1|root,COG5652@2|Bacteria,1NIUW@1224|Proteobacteria	1224|Proteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GGS1_k127_2711264_0	269797.Mbar_A0131	2.006e-64	232.0	COG2144@1|root,arCOG00640@2157|Archaea,2XTU9@28890|Euryarchaeota,2N979@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM AIR synthase related protein	-	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
GGS1_k127_2715186_0	1501230.ET33_03665	5.276e-29	125.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,4IS8X@91061|Bacilli,277CZ@186822|Paenibacillaceae	91061|Bacilli	JM	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
GGS1_k127_2715186_3	1054217.TALC_00269	4.78e-05	49.0	arCOG06958@1|root,arCOG06958@2157|Archaea,2Y41U@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2715186_2	316274.Haur_2146	2.425e-06	55.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
GGS1_k127_2721039_1	1054217.TALC_00448	4.55e-26	116.0	COG0720@1|root,arCOG02172@2157|Archaea,2XXFY@28890|Euryarchaeota,241WN@183967|Thermoplasmata	183967|Thermoplasmata	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GGS1_k127_2721039_2	1236689.MMALV_03720	2.39e-25	115.0	COG4002@1|root,arCOG00854@2157|Archaea,2XXS9@28890|Euryarchaeota	28890|Euryarchaeota	S	methanogen marker protein 4	-	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
GGS1_k127_2721039_0	192952.MM_0306	4.503e-68	241.0	COG1234@1|root,arCOG00501@2157|Archaea,2XTJ9@28890|Euryarchaeota,2N96S@224756|Methanomicrobia	224756|Methanomicrobia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GGS1_k127_272389_1	439235.Dalk_1630	2.493e-25	108.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,42U2Z@68525|delta/epsilon subdivisions,2WR58@28221|Deltaproteobacteria,2MM2N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
GGS1_k127_272389_0	335543.Sfum_0017	1.638e-120	400.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MRFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase, alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GGS1_k127_2726278_1	331678.Cphamn1_0895	4.863e-18	97.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	cdu2	-	-	ko:K05564,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6,2.A.63.1	-	-	Na_H_Exchanger,Usp
GGS1_k127_2726278_0	404589.Anae109_0989	3.394e-191	621.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
GGS1_k127_2731797_2	1352941.M877_02525	0.0003863	53.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
GGS1_k127_2731797_1	1385520.N802_00155	1.454e-06	61.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4FFJG@85021|Intrasporangiaceae	201174|Actinobacteria	S	protease	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
GGS1_k127_2731797_0	153721.MYP_2859	1.922e-25	109.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_2732510_3	290397.Adeh_3195	2.192e-38	148.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_2732510_2	266779.Meso_0627	6.62e-44	164.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,43PGY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_2732510_4	1463917.JODC01000013_gene1329	8.241e-10	73.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
GGS1_k127_2732510_1	192952.MM_1017	5.537e-44	171.0	COG1912@1|root,arCOG04309@2157|Archaea,2XUEW@28890|Euryarchaeota,2N9T8@224756|Methanomicrobia	224756|Methanomicrobia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
GGS1_k127_2732510_0	1121422.AUMW01000006_gene759	1.076e-49	195.0	COG0477@1|root,COG2814@2|Bacteria,1UGP8@1239|Firmicutes,24ENP@186801|Clostridia	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_2734836_1	456442.Mboo_0894	9.434e-202	650.0	COG2060@1|root,COG2156@1|root,arCOG04804@2157|Archaea,arCOG04805@2157|Archaea,2XU4N@28890|Euryarchaeota,2NANG@224756|Methanomicrobia	224756|Methanomicrobia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
GGS1_k127_2734836_0	456442.Mboo_0444	1.321e-276	869.0	COG2216@1|root,arCOG01577@2157|Archaea,2XVYI@28890|Euryarchaeota,2NAIX@224756|Methanomicrobia	224756|Methanomicrobia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
GGS1_k127_2735764_1	1232410.KI421427_gene1286	1.395e-40	163.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GGS1_k127_2735764_4	1550091.JROE01000008_gene3401	0.0005521	52.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes,1IP4K@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GGS1_k127_2735764_0	1054217.TALC_00151	9.956e-246	781.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,241M2@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GGS1_k127_2735764_2	387631.Asulf_01772	9.535e-18	85.0	COG1828@1|root,arCOG04462@2157|Archaea,2XYPB@28890|Euryarchaeota,246HY@183980|Archaeoglobi	183980|Archaeoglobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
GGS1_k127_2735764_3	1179773.BN6_66510	1.952e-12	71.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_2739606_0	762984.HMPREF9445_00989	1.247e-24	108.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,2FMSJ@200643|Bacteroidia,4AMB0@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GGS1_k127_2739606_1	195522.BD01_1811	2.378e-08	67.0	COG1572@1|root,COG3889@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02545@1|root,arCOG02554@1|root,arCOG03439@1|root,arCOG01672@2157|Archaea,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,arCOG02554@2157|Archaea,arCOG03439@2157|Archaea,arCOG07086@2157|Archaea,2XU6I@28890|Euryarchaeota,245EQ@183968|Thermococci	183968|Thermococci	S	solute binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GGS1_k127_2748213_0	439481.Aboo_0743	7.822e-88	292.0	COG1697@1|root,arCOG04143@2157|Archaea,2XTNQ@28890|Euryarchaeota,3F2HT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
GGS1_k127_2748213_2	304371.MCP_2550	1.543e-29	125.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,2NBB8@224756|Methanomicrobia	224756|Methanomicrobia	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
GGS1_k127_2748213_1	596152.DesU5LDRAFT_2749	1.432e-83	283.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,2M7X8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_7,Oxidored_q6
GGS1_k127_275325_1	1121924.ATWH01000001_gene4299	2.513e-12	81.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
GGS1_k127_275325_0	593117.TGAM_0970	2.353e-23	110.0	COG0419@1|root,COG2247@1|root,COG2319@1|root,COG5306@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG00368@2157|Archaea,arCOG00388@2157|Archaea,arCOG02491@2157|Archaea,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
GGS1_k127_2764136_0	266117.Rxyl_1964	3.594e-27	119.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GGS1_k127_278828_1	1324957.K933_02946	6.456e-25	111.0	COG0500@1|root,arCOG04583@2157|Archaea,2XTVC@28890|Euryarchaeota,23ST5@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GGS1_k127_278828_0	416348.Hlac_2824	6.185e-30	133.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_278828_2	1122622.ATWJ01000009_gene3319	0.0002177	44.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria,4FGSP@85021|Intrasporangiaceae	201174|Actinobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GGS1_k127_2808272_2	1385935.N836_16225	9.089e-58	211.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
GGS1_k127_2808272_1	439481.Aboo_1131	6.411e-227	715.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
GGS1_k127_2808272_0	673860.AciM339_1459	4.239e-227	716.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
GGS1_k127_2808272_5	1236689.MMALV_00260	2.517e-22	107.0	COG1777@1|root,arCOG01684@2157|Archaea,2Y0DG@28890|Euryarchaeota,3F2TC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K07721	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
GGS1_k127_2808272_4	1236689.MMALV_15330	2.129e-34	137.0	COG0361@1|root,arCOG01179@2157|Archaea,2XXX0@28890|Euryarchaeota,3F2RM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	eif1a	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
GGS1_k127_2808272_3	1094980.Mpsy_1474	1.905e-51	198.0	COG1718@1|root,arCOG01180@2157|Archaea,2XU2H@28890|Euryarchaeota,2N9ET@224756|Methanomicrobia	224756|Methanomicrobia	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
GGS1_k127_28086_0	926569.ANT_20730	3.504e-223	721.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GGS1_k127_28086_1	324602.Caur_0392	1.325e-15	92.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,2GA7Y@200795|Chloroflexi,376PQ@32061|Chloroflexia	32061|Chloroflexia	M	SMART Parallel beta-helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NPCBM_assoc
GGS1_k127_280877_1	634498.mru_0715	1.563e-26	115.0	COG0463@1|root,COG1819@1|root,arCOG01385@2157|Archaea,arCOG01393@2157|Archaea,2XVTU@28890|Euryarchaeota,23NU6@183925|Methanobacteria	183925|Methanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3,Glycos_transf_2
GGS1_k127_280877_0	304371.MCP_0143	2.127e-34	147.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,2N9R4@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_280877_2	444158.MmarC6_1741	1.617e-06	57.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,23QRU@183939|Methanococci	183939|Methanococci	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
GGS1_k127_2843395_1	1261545.MBE-HAL_1076	8.701e-42	166.0	COG0697@1|root,arCOG00271@2157|Archaea,2XT64@28890|Euryarchaeota,23TZT@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GGS1_k127_2843395_0	338966.Ppro_0868	8.727e-50	194.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria,43SA5@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	dmeF	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GGS1_k127_2852542_2	439481.Aboo_0448	1.84e-08	60.0	COG2339@1|root,arCOG02985@2157|Archaea	2157|Archaea	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GGS1_k127_2852542_0	1150474.JQJI01000001_gene1763	2.755e-85	298.0	COG0549@1|root,COG0549@2|Bacteria,2GCB0@200918|Thermotogae	200918|Thermotogae	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GGS1_k127_2852542_1	382464.ABSI01000011_gene3064	1.013e-72	251.0	COG4760@1|root,COG4760@2|Bacteria,46ZIY@74201|Verrucomicrobia,2IV4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
GGS1_k127_2864439_4	381666.H16_A3742	4.147e-21	105.0	COG2267@1|root,COG2267@2|Bacteria,1R9DT@1224|Proteobacteria,2VPU4@28216|Betaproteobacteria,1KGYG@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GGS1_k127_2864439_3	1198452.Jab_2c09850	8.599e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_2864439_1	861299.J421_0542	8.793e-77	265.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GGS1_k127_2864439_5	710696.Intca_3007	1.071e-17	88.0	COG2197@1|root,COG2197@2|Bacteria,2IBDE@201174|Actinobacteria	201174|Actinobacteria	T	Two component transcriptional regulator, luxr family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GGS1_k127_2864439_0	649638.Trad_2528	1.482e-110	375.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GGS1_k127_2864439_2	649638.Trad_2529	4.875e-55	196.0	COG1028@1|root,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GGS1_k127_2866806_1	326427.Cagg_3340	2.709e-103	341.0	COG0863@1|root,COG0863@2|Bacteria,2G6M6@200795|Chloroflexi,376YY@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GGS1_k127_2866806_0	63737.Npun_F5602	2.59e-127	418.0	COG3227@1|root,COG3227@2|Bacteria,1G3KW@1117|Cyanobacteria,1HMHN@1161|Nostocales	1117|Cyanobacteria	E	PFAM Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
GGS1_k127_2870446_0	1385511.N783_04790	9.174e-57	225.0	COG1404@1|root,COG1404@2|Bacteria,1UZRQ@1239|Firmicutes,4HEVW@91061|Bacilli	91061|Bacilli	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8,SLH
GGS1_k127_2870446_1	268739.Nmlp_3862	4.934e-47	195.0	COG0293@1|root,arCOG00079@2157|Archaea,2XT12@28890|Euryarchaeota,23T6V@183963|Halobacteria	183963|Halobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rrmJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,TRAM
GGS1_k127_2897335_2	880072.Desac_2928	8.709e-15	81.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MQS2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
GGS1_k127_2897335_1	673860.AciM339_1484	1.998e-21	104.0	COG1497@1|root,arCOG04399@2157|Archaea,2XU16@28890|Euryarchaeota,3F397@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Regulatory protein Crp	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
GGS1_k127_2897335_0	1236902.ANAS01000009_gene2563	7.303e-41	158.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4EH64@85012|Streptosporangiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
GGS1_k127_2898684_0	886293.Sinac_4025	3.56e-33	145.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
GGS1_k127_2898684_1	593117.TGAM_1663	1.739e-08	64.0	COG2306@1|root,arCOG05760@2157|Archaea,2XX0W@28890|Euryarchaeota,243ZF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
GGS1_k127_2902650_1	273075.Ta1148	4.839e-151	497.0	COG1793@1|root,arCOG01347@2157|Archaea,2XTCK@28890|Euryarchaeota,241JJ@183967|Thermoplasmata	183967|Thermoplasmata	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
GGS1_k127_2902650_2	673860.AciM339_0266	1.325e-80	281.0	COG1235@1|root,arCOG00499@2157|Archaea,2XT48@28890|Euryarchaeota,3F2JB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GGS1_k127_2902650_3	1054217.TALC_00715	9.536e-74	269.0	COG0037@1|root,arCOG00042@2157|Archaea,2XTEZ@28890|Euryarchaeota,241N6@183967|Thermoplasmata	183967|Thermoplasmata	D	PP-loop family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
GGS1_k127_2902650_7	913325.N799_08045	1.332e-13	83.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,1X3HG@135614|Xanthomonadales	135614|Xanthomonadales	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GGS1_k127_2902650_0	70601.3257107	4.425e-190	613.0	COG0441@1|root,arCOG00401@2157|Archaea,2XTFI@28890|Euryarchaeota,242P8@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
GGS1_k127_2902650_4	797209.ZOD2009_20013	4.56e-26	119.0	COG1986@1|root,arCOG01223@2157|Archaea,2XWGY@28890|Euryarchaeota,23V74@183963|Halobacteria	183963|Halobacteria	H	Phosphopantetheine adenylyltransferase	coaD	-	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GGS1_k127_2902650_8	387631.Asulf_01695	0.0005067	45.0	COG4068@1|root,arCOG04390@2157|Archaea	2157|Archaea	S	Uncharacterized protein containing a Zn-ribbon (DUF2116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
GGS1_k127_2902650_6	673860.AciM339_0905	6.108e-24	106.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GGS1_k127_2902650_5	673860.AciM339_0905	3.066e-25	111.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GGS1_k127_2903586_0	439481.Aboo_1381	3.129e-221	729.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,3F2HY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GGS1_k127_2903586_1	439481.Aboo_1382	3.656e-40	166.0	COG1354@1|root,arCOG02610@2157|Archaea,2XZHK@28890|Euryarchaeota,3F2QG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GGS1_k127_2916745_5	1278073.MYSTI_07982	9.683e-23	98.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GGS1_k127_2916745_4	234267.Acid_4923	5.784e-26	113.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SGL
GGS1_k127_2916745_1	304371.MCP_1094	4.658e-74	277.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,2NA71@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GGS1_k127_2916745_0	767817.Desgi_2383	5.834e-77	269.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,260WJ@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GGS1_k127_2916745_2	1041930.Mtc_0314	4.832e-50	189.0	COG0614@1|root,arCOG04233@2157|Archaea,2XUJY@28890|Euryarchaeota,2NAVH@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GGS1_k127_2916745_3	479434.Sthe_3160	1.738e-28	123.0	COG3411@1|root,COG3411@2|Bacteria,2GA0H@200795|Chloroflexi,27YC7@189775|Thermomicrobia	189775|Thermomicrobia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2916745_7	1318628.MARLIPOL_15944	5.116e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,1SZ3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GGS1_k127_2916745_6	246197.MXAN_5069	4.235e-15	85.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
GGS1_k127_2946348_0	673860.AciM339_0604	2.328e-40	164.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4UK@28890|Euryarchaeota,3F2ZZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	GvpD gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_2946348_1	439481.Aboo_0215	1.292e-10	68.0	COG1719@1|root,arCOG01688@2157|Archaea	2157|Archaea	K	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,V4R
GGS1_k127_2963739_5	224325.AF_1479	0.0001698	50.0	COG1487@1|root,arCOG02219@2157|Archaea,2Y1PM@28890|Euryarchaeota	28890|Euryarchaeota	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GGS1_k127_2963739_3	1033806.HTIA_2372	4.058e-07	55.0	arCOG08550@1|root,arCOG08550@2157|Archaea,2Y18M@28890|Euryarchaeota,23YJ8@183963|Halobacteria	183963|Halobacteria	S	Pfam:DUF217	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
GGS1_k127_2963739_2	926550.CLDAP_38570	4.513e-72	253.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GGS1_k127_2963739_1	521045.Kole_0624	5.721e-90	313.0	COG1028@1|root,COG1028@2|Bacteria	521045.Kole_0624|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2963739_4	1142394.PSMK_09530	1.851e-06	55.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GGS1_k127_2963739_0	760568.Desku_3120	1.248e-136	447.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,260TY@186807|Peptococcaceae	186801|Clostridia	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GGS1_k127_2968182_3	1114856.C496_20400	0.000172	49.0	COG2402@1|root,arCOG04502@2157|Archaea,2XWJ1@28890|Euryarchaeota,23V81@183963|Halobacteria	183963|Halobacteria	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GGS1_k127_2968182_0	1123228.AUIH01000092_gene552	1.061e-35	156.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2968182_1	1177179.A11A3_06958	1.82e-31	143.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2968182_2	684949.ATTJ01000004_gene3495	3.861e-09	68.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	exsG	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
GGS1_k127_2988001_0	1183438.GKIL_2511	4.355e-146	480.0	COG2986@1|root,COG2986@2|Bacteria,1G3FJ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.24,4.3.1.3	ko:K01745,ko:K10775	ko00340,ko00360,ko00940,ko01100,ko01110,map00340,map00360,map00940,map01100,map01110	M00039,M00045,M00137,M00350	R00697,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GGS1_k127_2988001_2	304371.MCP_1766	5.493e-55	215.0	arCOG04521@1|root,arCOG04521@2157|Archaea,2XUMG@28890|Euryarchaeota,2NAW2@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_2988001_1	679926.Mpet_1979	6.633e-70	245.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT2Y@28890|Euryarchaeota,2N9GE@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_2988001_3	693661.Arcve_1550	1.074e-19	96.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_3002630_1	545695.TREAZ_0546	0.0005261	46.0	COG0195@1|root,COG0195@2|Bacteria,2J624@203691|Spirochaetes	203691|Spirochaetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1,zf-ribbon_3
GGS1_k127_3002630_0	877424.ATWC01000003_gene1711	5.604e-10	68.0	COG0745@1|root,COG0745@2|Bacteria,1TT5H@1239|Firmicutes,24934@186801|Clostridia,27K21@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GGS1_k127_300390_2	446465.Bfae_24300	2.466e-05	51.0	COG0695@1|root,COG0695@2|Bacteria,2HHHX@201174|Actinobacteria,4FD39@85020|Dermabacteraceae	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
GGS1_k127_300390_1	1333523.L593_02315	2.045e-44	173.0	COG0110@1|root,arCOG01850@2157|Archaea,2XWH3@28890|Euryarchaeota,23V5N@183963|Halobacteria	183963|Halobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	yvoF	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
GGS1_k127_300390_0	1356852.N008_16080	9.612e-115	384.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,47KIQ@768503|Cytophagia	976|Bacteroidetes	G	Trehalose-phosphatase	otsB	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
GGS1_k127_3010833_1	644281.MFS40622_0783	6.335e-06	59.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23R7V@183939|Methanococci	183939|Methanococci	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GGS1_k127_3010833_0	35841.BT1A1_2469	1.671e-155	501.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus	91061|Bacilli	C	Malate dehydrogenase	ytsJ	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
GGS1_k127_3016784_2	55952.BU52_10230	9.473e-06	58.0	COG4733@1|root,COG5498@1|root,COG4733@2|Bacteria,COG5498@2|Bacteria,2GNW3@201174|Actinobacteria	201174|Actinobacteria	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_81,fn3
GGS1_k127_3016784_1	1094980.Mpsy_0913	1.11e-38	156.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,2N9DU@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
GGS1_k127_3016784_0	304371.MCP_0098	1.054e-127	418.0	COG1899@1|root,arCOG04142@2157|Archaea,2XUTF@28890|Euryarchaeota,2N9AF@224756|Methanomicrobia	224756|Methanomicrobia	O	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys-1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GGS1_k127_3038304_0	439481.Aboo_1474	4.656e-28	118.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,3F2U4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
GGS1_k127_3038304_2	387631.Asulf_00629	2.841e-27	123.0	COG0102@1|root,arCOG04242@2157|Archaea,2XWN6@28890|Euryarchaeota,2470M@183980|Archaeoglobi	183980|Archaeoglobi	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GGS1_k127_3038304_1	439481.Aboo_1476	4.851e-28	127.0	COG0088@1|root,arCOG04243@2157|Archaea,2XWK0@28890|Euryarchaeota,3F2N4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the universal ribosomal protein uS9 family	rps9	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GGS1_k127_304380_4	69014.TK1319	4.79e-12	67.0	COG2167@1|root,arCOG04177@2157|Archaea,2XZSY@28890|Euryarchaeota,244NC@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
GGS1_k127_304380_3	304371.MCP_0015	7.822e-21	96.0	COG2118@1|root,arCOG04179@2157|Archaea,2XZUR@28890|Euryarchaeota,2N9ZR@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
GGS1_k127_304380_1	439481.Aboo_0024	5.173e-46	178.0	COG2238@1|root,arCOG01344@2157|Archaea,2XXA6@28890|Euryarchaeota,3F2P6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
GGS1_k127_304380_0	456442.Mboo_1172	1.971e-70	273.0	COG0457@1|root,arCOG03048@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03048@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
GGS1_k127_304380_2	439481.Aboo_1307	4.853e-22	102.0	arCOG05357@1|root,arCOG05357@2157|Archaea,2Y1B1@28890|Euryarchaeota,3F2VN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_304380_5	219305.MCAG_01372	6.324e-06	55.0	COG2267@1|root,COG2267@2|Bacteria,2I5HD@201174|Actinobacteria,4DMN1@85008|Micromonosporales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GGS1_k127_3049291_5	1117315.AHCA01000005_gene1259	0.000714	52.0	COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,2Q5EX@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
GGS1_k127_3049291_2	410358.Mlab_0638	4.289e-25	117.0	COG0561@1|root,arCOG01213@2157|Archaea,2XX94@28890|Euryarchaeota,2N9JY@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the dephosphorylation of 2-phosphoglycolate	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
GGS1_k127_3049291_0	861299.J421_4356	1.168e-67	258.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_3049291_3	670487.Ocepr_1826	1.13e-14	86.0	COG0577@1|root,COG0577@2|Bacteria,1WIT2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GGS1_k127_3049291_4	861299.J421_4357	6.835e-14	84.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GGS1_k127_3049291_1	70601.3258323	3.33e-50	188.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,24332@183968|Thermococci	183968|Thermococci	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
GGS1_k127_3054139_0	273075.Ta0840	5.417e-85	286.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,241IB@183967|Thermoplasmata	183967|Thermoplasmata	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
GGS1_k127_3054139_1	673860.AciM339_1207	5.141e-28	114.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75G@28890|Euryarchaeota,3F3FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GGS1_k127_3054139_2	351160.LRC36	4.662e-05	53.0	COG3612@1|root,arCOG04418@2157|Archaea,2XXT8@28890|Euryarchaeota,2NA4A@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterized protein conserved in archaea (DUF2240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2240
GGS1_k127_3074963_0	767817.Desgi_3723	1.186e-22	110.0	COG2221@1|root,COG2221@2|Bacteria,1VE02@1239|Firmicutes,24PGA@186801|Clostridia,265BJ@186807|Peptococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7,NIR_SIR
GGS1_k127_3085046_0	574087.Acear_2299	9.102e-164	542.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia	186801|Clostridia	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GGS1_k127_3085046_1	243274.THEMA_03585	4.234e-51	189.0	COG1894@1|root,COG1894@2|Bacteria,2GCCH@200918|Thermotogae	200918|Thermotogae	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GGS1_k127_3096199_4	1047013.AQSP01000142_gene122	0.0004861	48.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
GGS1_k127_3096199_2	710696.Intca_0863	6.235e-05	51.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GGS1_k127_3096199_3	368407.Memar_2151	0.0001178	46.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,2N94I@224756|Methanomicrobia	224756|Methanomicrobia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GGS1_k127_3096199_0	268739.Nmlp_2020	3.658e-49	189.0	COG0697@1|root,arCOG00271@2157|Archaea,2XTD0@28890|Euryarchaeota,23TNI@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GGS1_k127_3096199_1	70601.3257066	2.284e-27	124.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,243HQ@183968|Thermococci	183968|Thermococci	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
GGS1_k127_3104773_0	1120746.CCNL01000014_gene2162	1.64e-71	248.0	COG0399@1|root,COG0399@2|Bacteria,2NQAE@2323|unclassified Bacteria	2|Bacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
GGS1_k127_3104773_1	383372.Rcas_3603	5.583e-27	119.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_3104773_2	1121945.ATXS01000001_gene1973	1.237e-09	65.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXRS@28890|Euryarchaeota,23W7D@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GGS1_k127_3114309_1	694427.Palpr_2927	5.853e-64	229.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,2FWWQ@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
GGS1_k127_3114309_0	1379698.RBG1_1C00001G0857	1.641e-103	355.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3114309_3	880073.Calab_1837	0.000316	52.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3
GGS1_k127_3114309_2	57918.XP_004309481.1	4.362e-21	107.0	2926D@1|root,2R92T@2759|Eukaryota,37JID@33090|Viridiplantae,3G8IN@35493|Streptophyta,4JKVH@91835|fabids	35493|Streptophyta	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
GGS1_k127_3118996_0	203119.Cthe_1322	2.618e-113	376.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GGS1_k127_3118996_1	1209989.TepiRe1_1198	7.038e-92	316.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42ESV@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GGS1_k127_3118996_2	304371.MCP_2998	8.46e-87	293.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,2N96N@224756|Methanomicrobia	224756|Methanomicrobia	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos,tRNA_anti-codon
GGS1_k127_3128361_2	1236689.MMALV_05600	4.169e-68	238.0	COG1709@1|root,arCOG04060@2157|Archaea,2XT58@28890|Euryarchaeota,3F2M5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07731	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
GGS1_k127_3128361_0	339860.Msp_0117	1.824e-140	461.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23NSI@183925|Methanobacteria	183925|Methanobacteria	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
GGS1_k127_3128361_1	1041930.Mtc_2447	1.527e-127	438.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
GGS1_k127_3128361_3	673860.AciM339_0716	1.603e-44	168.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,3F2RZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	DUF35 OB-fold domain, acyl-CoA-associated	acaC	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
GGS1_k127_3128361_4	589924.Ferp_0985	0.0002693	50.0	COG4004@1|root,arCOG04412@2157|Archaea,2Y1TD@28890|Euryarchaeota,246DU@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_313092_1	314271.RB2654_06439	4.555e-14	87.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
GGS1_k127_313092_0	67373.JOBF01000012_gene3979	4.288e-88	307.0	COG2271@1|root,COG2271@2|Bacteria,2I8XD@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GGS1_k127_3132360_0	673860.AciM339_0427	8.266e-114	391.0	COG0126@1|root,arCOG00496@2157|Archaea,2XSXX@28890|Euryarchaeota,3F2JM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GGS1_k127_3132360_1	1120973.AQXL01000130_gene1214	4.956e-42	163.0	COG1893@1|root,COG1893@2|Bacteria,1V4CU@1239|Firmicutes,4I3PY@91061|Bacilli,279ZI@186823|Alicyclobacillaceae	91061|Bacilli	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	-	-	-	-	-	-	-	-	-	-	ApbA,ApbA_C
GGS1_k127_3133552_0	1279009.ADICEAN_03353	1.699e-22	114.0	COG4547@1|root,COG4932@1|root,COG5644@1|root,COG4547@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
GGS1_k127_3145334_1	1116232.AHBF01000125_gene9441	1.381e-11	79.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
GGS1_k127_3145334_0	471854.Dfer_3148	6.194e-30	139.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
GGS1_k127_316625_10	1150864.MILUP08_46540	0.0001147	56.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2IF2T@201174|Actinobacteria,4DBYG@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Kelch_1,Peptidase_S8
GGS1_k127_316625_2	304371.MCP_1462	1.756e-39	160.0	COG1624@1|root,arCOG04453@2157|Archaea,2XTR1@28890|Euryarchaeota,2N9M8@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a	dacZ	-	-	-	-	-	-	-	-	-	-	-	DisA_N
GGS1_k127_316625_8	1365176.N186_05190	5.864e-16	80.0	COG1254@1|root,arCOG01674@2157|Archaea,2XR8S@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GGS1_k127_316625_6	673860.AciM339_1397	3.695e-30	127.0	COG1051@1|root,COG2005@1|root,arCOG00223@2157|Archaea,arCOG01075@2157|Archaea,2XXS4@28890|Euryarchaeota,3F39U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GGS1_k127_316625_1	552811.Dehly_0642	3.727e-58	220.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GGS1_k127_316625_5	768679.TTX_2108	3.784e-36	145.0	COG0521@1|root,arCOG00214@2157|Archaea,2XQH2@28889|Crenarchaeota	28889|Crenarchaeota	H	TIGRFAM molybdenum cofactor synthesis domain	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
GGS1_k127_316625_3	272557.APE_1350.1	9.931e-39	158.0	COG0315@1|root,arCOG01530@2157|Archaea,2XQM5@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GGS1_k127_316625_7	224324.aq_2181	8.044e-26	113.0	COG0314@1|root,COG0314@2|Bacteria,2G551@200783|Aquificae	200783|Aquificae	H	molybdopterin	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
GGS1_k127_316625_4	69014.TK1491	1.069e-36	153.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,243ZM@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
GGS1_k127_316625_0	1297581.H919_02552	2.64e-80	275.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,21W26@150247|Anoxybacillus	91061|Bacilli	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GGS1_k127_316625_9	1410668.JNKC01000022_gene2166	3.1e-05	53.0	2EEAH@1|root,3384Y@2|Bacteria,1VGPJ@1239|Firmicutes,24R7Q@186801|Clostridia,36NER@31979|Clostridiaceae	186801|Clostridia	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_3173356_1	1434325.AZQN01000004_gene1625	1.201e-11	74.0	2E08S@1|root,32VWE@2|Bacteria,4P394@976|Bacteroidetes,47UXB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3173356_0	224719.Abm4_0181	6.652e-106	357.0	COG0119@1|root,arCOG02092@2157|Archaea,2XV8D@28890|Euryarchaeota,23PFQ@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	aksA	-	2.3.3.14	ko:K10977	ko00300,ko00620,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map00680,map01100,map01120,map01130,map01210,map01230	M00608	R00271,R08213,R08331,R08332	RC00004,RC00067,RC02149,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GGS1_k127_3179377_1	1459636.NTE_00013	6.774e-36	141.0	COG2085@1|root,arCOG00457@2157|Archaea	2157|Archaea	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,HTH_10
GGS1_k127_3179377_0	290397.Adeh_2028	7.174e-99	332.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,42T9A@68525|delta/epsilon subdivisions,2WPAS@28221|Deltaproteobacteria,2YVAM@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.2	ko:K00002	ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220	M00014	R00746,R01041,R01481,R05231	RC00087,RC00088,RC00099,RC00108	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Aldo_ket_red
GGS1_k127_3180844_0	656024.FsymDg_3413	6.544e-32	130.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria,4ETJS@85013|Frankiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3192552_0	1054217.TALC_00658	2.467e-216	686.0	COG1245@1|root,arCOG00187@2157|Archaea,2XSZE@28890|Euryarchaeota,241KJ@183967|Thermoplasmata	183967|Thermoplasmata	E	Possible Fer4-like domain in RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
GGS1_k127_3192552_1	523845.AQXV01000026_gene1469	1.736e-54	220.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
GGS1_k127_3192552_5	575540.Isop_3323	0.0007791	50.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
GGS1_k127_3192552_2	593750.Metfor_0908	1.833e-13	76.0	COG0864@1|root,arCOG01008@2157|Archaea,2XWHW@28890|Euryarchaeota,2N9KS@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
GGS1_k127_3193756_0	439481.Aboo_0197	1.083e-198	633.0	COG0640@1|root,COG1201@1|root,arCOG00394@2157|Archaea,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2IQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DEAD/H associated	lhr2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GGS1_k127_3193756_2	443144.GM21_2451	7.073e-22	112.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,fn3
GGS1_k127_3193756_1	1298593.TOL_0565	4.32e-23	104.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,1RREG@1236|Gammaproteobacteria,1XJ9N@135619|Oceanospirillales	135619|Oceanospirillales	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GGS1_k127_3196870_1	660470.Theba_2513	2.259e-38	155.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
GGS1_k127_3196870_0	1173023.KE650771_gene1231	2.016e-54	204.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1JHG3@1189|Stigonemataceae	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
GGS1_k127_3196870_2	1227497.C491_17212	0.0002061	44.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GGS1_k127_3210480_1	41875.XP_007511676.1	2.219e-15	88.0	28M8C@1|root,2S5PV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3210480_0	1104324.P186_2853	8.634e-43	168.0	COG0463@1|root,arCOG00894@2157|Archaea,2XQ9U@28889|Crenarchaeota	28889|Crenarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
GGS1_k127_3226433_0	1173023.KE650771_gene598	2.385e-39	169.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1JK6S@1189|Stigonemataceae	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
GGS1_k127_3243196_3	637905.SVI_3873	2.16e-16	83.0	COG2931@1|root,COG3227@1|root,COG3266@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,2Q92C@267890|Shewanellaceae	1236|Gammaproteobacteria	E	peptidase M4 thermolysin	proA	GO:0005575,GO:0005576	3.4.24.25,3.4.24.26	ko:K01399,ko:K08604	ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C
GGS1_k127_3243196_4	1123400.KB904758_gene2277	6.179e-13	77.0	COG1100@1|root,COG1100@2|Bacteria,1RIAW@1224|Proteobacteria,1S6H6@1236|Gammaproteobacteria,462KK@72273|Thiotrichales	72273|Thiotrichales	S	Ras of Complex, Roc, domain of DAPkinase	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_3243196_1	1521187.JPIM01000023_gene799	3.018e-33	136.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_3243196_2	351160.RCIX2113	6.872e-17	94.0	COG0784@1|root,arCOG03799@1|root,arCOG06712@1|root,arCOG02393@2157|Archaea,arCOG03799@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Anticodon_1,DUF835,GAF_2,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg,zinc_ribbon_2
GGS1_k127_3243196_5	456442.Mboo_1913	1.581e-06	57.0	COG1719@1|root,arCOG01688@2157|Archaea	2157|Archaea	K	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,V4R
GGS1_k127_3243196_6	749927.AMED_0787	0.000776	48.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
GGS1_k127_3243196_0	673860.AciM339_0753	5.823e-97	362.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
GGS1_k127_329996_0	1500893.JQNB01000001_gene2143	8.566e-27	126.0	COG0500@1|root,COG2226@2|Bacteria,1R8N9@1224|Proteobacteria,1SYVC@1236|Gammaproteobacteria,1X2Z5@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GGS1_k127_329996_1	1120936.KB907215_gene3950	2.158e-14	87.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
GGS1_k127_3309150_0	498848.TaqDRAFT_5000	3.461e-18	98.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1WKU1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Pkd domain containing protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	PPC
GGS1_k127_331418_0	316274.Haur_0016	3.966e-82	283.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GGS1_k127_331418_1	309801.trd_A0395	9.041e-63	222.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GGS1_k127_331894_0	529709.PYCH_08530	3.776e-65	244.0	COG1672@1|root,arCOG03166@2157|Archaea,2XTP2@28890|Euryarchaeota,242XG@183968|Thermococci	183968|Thermococci	K	ATPase, AAA superfamily	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_5,HTH_IclR
GGS1_k127_3330373_1	673860.AciM339_0907	0.00018	56.0	COG1361@1|root,arCOG02527@1|root,arCOG02089@2157|Archaea,arCOG02527@2157|Archaea,2Y6ZW@28890|Euryarchaeota,3F314@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3330373_0	1054217.TALC_00430	3.465e-318	1006.0	COG1933@1|root,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,241KH@183967|Thermoplasmata	183967|Thermoplasmata	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
GGS1_k127_3333733_1	323848.Nmul_A2158	5.784e-67	241.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria,373YE@32003|Nitrosomonadales	28216|Betaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
GGS1_k127_3333733_0	273075.Ta0068	1.415e-139	457.0	COG0160@1|root,arCOG00915@2157|Archaea,2Y83J@28890|Euryarchaeota,2421R@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GGS1_k127_3333733_5	1150399.AQYK01000001_gene1936	3.563e-23	110.0	COG0451@1|root,COG0451@2|Bacteria,2IFBI@201174|Actinobacteria,4FR5D@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GGS1_k127_3333733_4	1144275.COCOR_00436	3.874e-39	148.0	COG0640@1|root,COG0640@2|Bacteria,1N1QR@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_3333733_3	468059.AUHA01000003_gene1707	2.735e-39	162.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1ISXP@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GGS1_k127_3333733_2	1144275.COCOR_00437	9.465e-49	185.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GGS1_k127_3337459_0	1499967.BAYZ01000136_gene54	6.843e-43	169.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GGS1_k127_3337459_1	985053.VMUT_0474	1.708e-05	52.0	arCOG03723@1|root,arCOG03723@2157|Archaea,2XSIU@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PaREP1
GGS1_k127_333886_2	351160.RCIX2032	1.486e-88	307.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
GGS1_k127_333886_0	1094980.Mpsy_2506	8.319e-270	841.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2N93M@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
GGS1_k127_333886_8	1041930.Mtc_1397	1.148e-25	113.0	COG1436@1|root,arCOG04102@2157|Archaea,2XXYI@28890|Euryarchaeota,2N9YY@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
GGS1_k127_333886_4	565033.GACE_1733	6.345e-70	250.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,24612@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
GGS1_k127_333886_9	589924.Ferp_2307	9.706e-21	101.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,24687@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
GGS1_k127_333886_10	224325.AF_1160	2.329e-18	89.0	COG0636@1|root,arCOG02455@2157|Archaea	2157|Archaea	C	H transporting two-sector ATPase C subunit	ahaK	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
GGS1_k127_333886_1	1094980.Mpsy_2501	1.31e-99	354.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2N9EB@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-1	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
GGS1_k127_333886_13	1121945.ATXS01000004_gene1106	0.0002068	51.0	arCOG04596@1|root,arCOG04596@2157|Archaea,2XX20@28890|Euryarchaeota,23VPS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_333886_11	1122221.JHVI01000018_gene1525	2.245e-09	66.0	COG0723@1|root,COG0723@2|Bacteria,1WJBT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K15878	-	-	-	-	ko00000	-	-	-	Rieske
GGS1_k127_333886_3	797114.C475_10009	4.809e-80	295.0	COG1290@1|root,arCOG01721@2157|Archaea,2XUQH@28890|Euryarchaeota,23TXF@183963|Halobacteria	183963|Halobacteria	C	COG1290 Cytochrome b subunit of the bc complex	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
GGS1_k127_333886_6	335543.Sfum_1176	1.925e-43	179.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GGS1_k127_333886_5	374847.Kcr_0764	1.565e-44	180.0	COG1148@1|root,arCOG02235@2157|Archaea	2157|Archaea	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
GGS1_k127_333886_7	644281.MFS40622_0209	6.886e-29	130.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
GGS1_k127_333886_12	177437.HRM2_22750	7.745e-05	55.0	COG1148@1|root,COG2204@1|root,COG1148@2|Bacteria,COG2204@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MI9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	CT	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
GGS1_k127_3365445_2	1123355.JHYO01000004_gene2526	5.705e-05	54.0	COG0346@1|root,COG0346@2|Bacteria,1N810@1224|Proteobacteria,2UNCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_3365445_4	471853.Bcav_4164	0.0005702	51.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_3365445_1	1229909.NSED_01550	4.225e-46	185.0	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GGS1_k127_3365445_3	35754.JNYJ01000091_gene6213	7.303e-05	52.0	COG1225@1|root,COG1225@2|Bacteria,2IFM1@201174|Actinobacteria	201174|Actinobacteria	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
GGS1_k127_3365445_0	401053.AciPR4_1793	5.257e-61	218.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
GGS1_k127_336799_6	573370.DMR_02280	2.762e-16	79.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2MG7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GGS1_k127_336799_4	309807.SRU_1294	6.251e-38	149.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1FJBE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GGS1_k127_336799_1	644966.Tmar_1411	1.163e-62	227.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,3WDS0@538999|Clostridiales incertae sedis	186801|Clostridia	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GGS1_k127_336799_8	1265502.KB905938_gene2487	3.829e-05	55.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,4ADY6@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
GGS1_k127_336799_0	716544.wcw_1738	5.852e-88	310.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Meth_synt_1,Meth_synt_2
GGS1_k127_336799_3	266117.Rxyl_0842	2.131e-46	180.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
GGS1_k127_336799_2	342949.PNA2_1263	7.713e-57	206.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,242TP@183968|Thermococci	183968|Thermococci	Q	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GGS1_k127_336799_5	204669.Acid345_0682	7.909e-36	149.0	COG2159@1|root,COG3483@1|root,COG2159@2|Bacteria,COG3483@2|Bacteria,3Y5M2@57723|Acidobacteria,2JN36@204432|Acidobacteriia	204432|Acidobacteriia	E	Amidohydrolase	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
GGS1_k127_3370197_0	673860.AciM339_0248	1.127e-65	237.0	COG1244@1|root,arCOG01360@2157|Archaea,2XT5Q@28890|Euryarchaeota,3F2I0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	Radical_SAM
GGS1_k127_3370197_1	1236689.MMALV_12000	1.68e-59	220.0	COG1549@1|root,arCOG00990@2157|Archaea,2XT9W@28890|Euryarchaeota,3F2KU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Patch-forming domain C2 of tRNA-guanine transglycosylase	arcS	GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.6.1.97	ko:K07557	-	-	-	-	ko00000,ko01000	-	-	-	PUA,TGT,TGT_C2
GGS1_k127_3390295_3	406327.Mevan_1560	8.525e-09	66.0	COG0640@1|root,arCOG01686@2157|Archaea,2XYZ4@28890|Euryarchaeota,23R6H@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GGS1_k127_3390295_1	439481.Aboo_0595	2.135e-30	124.0	COG1695@1|root,arCOG00001@2157|Archaea,2Y761@28890|Euryarchaeota,3F3G7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GGS1_k127_3390295_2	1519464.HY22_13280	2.125e-14	79.0	COG3793@1|root,COG3793@2|Bacteria	2|Bacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB
GGS1_k127_3390295_0	760568.Desku_3414	1.347e-37	164.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes	1239|Firmicutes	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8,SLH,fn3
GGS1_k127_3397183_3	1489678.RDMS_09345	6.125e-05	48.0	COG1522@1|root,COG1522@2|Bacteria,1WKF0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GGS1_k127_3397183_1	304371.MCP_1009	1.978e-21	98.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,2NB7P@224756|Methanomicrobia	224756|Methanomicrobia	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
GGS1_k127_3397183_0	439481.Aboo_1449	3.81e-50	192.0	COG2078@1|root,arCOG01336@2157|Archaea,2XUAP@28890|Euryarchaeota,3F2RN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
GGS1_k127_3397183_2	425104.Ssed_1278	1.968e-07	55.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,2Q8Q7@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0382	AIRS,AIRS_C
GGS1_k127_3399328_0	563192.HMPREF0179_02844	1.896e-13	78.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SZ7@68525|delta/epsilon subdivisions,2WPA5@28221|Deltaproteobacteria,2MGED@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GGS1_k127_3411789_2	204669.Acid345_0920	2.188e-37	163.0	COG0457@1|root,COG0457@2|Bacteria,3Y3HT@57723|Acidobacteria,2JHSD@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_3411789_4	700598.Niako_1496	3.18e-05	57.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD
GGS1_k127_3411789_0	358681.BBR47_54980	1.231e-110	364.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,26R8M@186822|Paenibacillaceae	91061|Bacilli	I	Dehydrogenase	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GGS1_k127_3411789_1	926554.KI912677_gene2450	2.941e-83	292.0	COG0579@1|root,COG0579@2|Bacteria,1WMNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
GGS1_k127_3411789_3	869210.Marky_1960	5.689e-28	130.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1WIB3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
GGS1_k127_3411789_5	258533.BN977_02916	8.203e-05	51.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,233AV@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome c oxidase, subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GGS1_k127_3413617_1	273116.14324590	7.705e-09	61.0	COG1826@1|root,arCOG02694@2157|Archaea,2Y23W@28890|Euryarchaeota,242BR@183967|Thermoplasmata	183967|Thermoplasmata	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GGS1_k127_3413617_0	1279019.ARQK01000058_gene747	7.609e-144	467.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
GGS1_k127_3414637_0	572546.Arcpr_1001	6.961e-33	134.0	COG1814@1|root,arCOG01091@2157|Archaea,2XVWH@28890|Euryarchaeota,2467J@183980|Archaeoglobi	183980|Archaeoglobi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GGS1_k127_3414637_2	387631.Asulf_00018	1.123e-05	56.0	2BVY9@1|root,2N553@2157|Archaea,2Y1ZH@28890|Euryarchaeota,246I9@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3414637_1	1227499.C493_04326	1.285e-14	85.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23TI5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GGS1_k127_3423671_3	572546.Arcpr_0028	8.518e-06	51.0	COG2104@1|root,arCOG00535@2157|Archaea,2Y205@28890|Euryarchaeota,246JP@183980|Archaeoglobi	183980|Archaeoglobi	H	Sulfur transfer protein involved in thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GGS1_k127_3423671_5	931277.C448_12446	0.0002922	49.0	arCOG04629@1|root,arCOG04629@2157|Archaea,2XYMK@28890|Euryarchaeota,23WZZ@183963|Halobacteria	183963|Halobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GGS1_k127_3423671_4	565033.GACE_0512	1.138e-05	54.0	COG2405@1|root,arCOG00717@2157|Archaea,2XXNX@28890|Euryarchaeota	28890|Euryarchaeota	V	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
GGS1_k127_3423671_0	593750.Metfor_1912	9.498e-39	156.0	arCOG00787@1|root,arCOG00787@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
GGS1_k127_3423671_2	41431.PCC8801_0882	2.714e-08	61.0	COG0457@1|root,COG0457@2|Bacteria,1G2FI@1117|Cyanobacteria,3KHFG@43988|Cyanothece	1117|Cyanobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_3428930_0	387631.Asulf_00619	5.475e-67	237.0	COG2220@1|root,arCOG00497@2157|Archaea,2XTCN@28890|Euryarchaeota,245Z6@183980|Archaeoglobi	183980|Archaeoglobi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GGS1_k127_3428930_1	694440.JOMF01000006_gene472	4.377e-36	149.0	COG1571@1|root,arCOG01116@2157|Archaea,2XTUY@28890|Euryarchaeota,2NAPH@224756|Methanomicrobia	224756|Methanomicrobia	S	methanogenesis marker protein 11	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3448304_1	1121468.AUBR01000027_gene2896	5.947e-06	51.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,25MVF@186801|Clostridia,42IFE@68295|Thermoanaerobacterales	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GGS1_k127_3448304_0	439481.Aboo_0090	7.456e-19	90.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75P@28890|Euryarchaeota,3F3FQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GGS1_k127_3451073_1	338963.Pcar_1288	1.14e-08	57.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,43V3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GGS1_k127_3451073_0	269797.Mbar_A0010	2.903e-31	137.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,2N98H@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
GGS1_k127_3456357_0	439481.Aboo_0186	6.124e-53	188.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,3F2II@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
GGS1_k127_3456357_1	661478.OP10G_4118	5.69e-37	147.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GGS1_k127_3456357_2	1499499.EV06_1487	9.717e-09	64.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1MM8U@1212|Prochloraceae	1117|Cyanobacteria	O	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_17,TPR_8,Trypsin_2
GGS1_k127_346704_0	443152.MDG893_02905	2.116e-09	71.0	COG2706@1|root,COG2931@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,1R0AU@1224|Proteobacteria,1S2TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3467908_0	1236689.MMALV_02290	1.102e-57	215.0	COG1498@1|root,arCOG01923@2157|Archaea,2XUEA@28890|Euryarchaeota,3F2QB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	snoRNA binding domain, fibrillarin	nop5	GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
GGS1_k127_347683_0	941449.dsx2_2708	2.423e-28	131.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2M9D1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
GGS1_k127_347683_1	633148.Tagg_0225	7.525e-08	65.0	COG1014@1|root,arCOG01602@2157|Archaea,2XQTC@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
GGS1_k127_3502900_2	439481.Aboo_1357	3.578e-13	79.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3502900_0	273075.Ta1509	2.228e-161	519.0	COG0112@1|root,arCOG00070@2157|Archaea,2XU0H@28890|Euryarchaeota,241JA@183967|Thermoplasmata	183967|Thermoplasmata	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GGS1_k127_3502900_1	673860.AciM339_0628	4.76e-23	102.0	arCOG05238@1|root,arCOG05238@2157|Archaea,2Y0YG@28890|Euryarchaeota,3F3EA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3502900_3	439481.Aboo_0405	1.998e-09	61.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
GGS1_k127_3522534_1	330214.NIDE3895	3.987e-24	117.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GGS1_k127_3522534_0	243365.CV_0600	6.175e-30	123.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KQHZ@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GGS1_k127_3534644_2	1343739.PAP_07685	8.225e-60	220.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,242SQ@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GGS1_k127_3534644_4	1121920.AUAU01000012_gene2613	1.889e-37	144.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
GGS1_k127_3534644_1	555779.Dthio_PD0362	7.197e-67	256.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,42TR0@68525|delta/epsilon subdivisions,2WQ94@28221|Deltaproteobacteria,2MAP4@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_hydro_8,Glyco_trans_2_3,Glycos_transf_2,PilZ
GGS1_k127_3534644_3	316274.Haur_3105	1.557e-54	212.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	scpD	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
GGS1_k127_3534644_0	177437.HRM2_23250	3.109e-153	499.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GGS1_k127_3534644_5	1227487.C474_12841	3.725e-11	65.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,23T4H@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
GGS1_k127_354033_4	1183377.Py04_1263	2.317e-09	66.0	COG2245@1|root,arCOG01644@2157|Archaea,2XY66@28890|Euryarchaeota,24464@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF996
GGS1_k127_354033_3	1173026.Glo7428_0554	8.709e-15	81.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
GGS1_k127_354033_0	1121403.AUCV01000040_gene4303	7.656e-251	835.0	COG1572@1|root,COG1974@1|root,COG1572@2|Bacteria,COG1974@2|Bacteria,1NHGZ@1224|Proteobacteria,42XGC@68525|delta/epsilon subdivisions,2WSK0@28221|Deltaproteobacteria,2MM7M@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
GGS1_k127_354033_6	1267535.KB906767_gene619	1.38e-05	60.0	COG2165@1|root,COG2165@2|Bacteria,3Y4X6@57723|Acidobacteria	57723|Acidobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
GGS1_k127_354033_1	1121033.AUCF01000014_gene1294	2.212e-102	349.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,2JRUI@204441|Rhodospirillales	204441|Rhodospirillales	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
GGS1_k127_354033_5	335659.S23_54210	5.944e-06	57.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,3JV7R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the SOS response-associated peptidase family	MA20_42060	-	-	-	-	-	-	-	-	-	-	-	SRAP
GGS1_k127_354033_2	1125863.JAFN01000001_gene2057	3.21e-51	188.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GGS1_k127_3578277_1	1463887.KL590021_gene491	3.462e-07	62.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	eamA	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
GGS1_k127_3578277_0	1089545.KB913037_gene7942	2.981e-07	59.0	COG5078@1|root,COG5078@2|Bacteria,2IJY9@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Ubiquitin-conjugating	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3595833_0	404589.Anae109_0769	5.832e-05	58.0	COG0484@1|root,COG2199@1|root,COG3064@1|root,COG0484@2|Bacteria,COG3064@2|Bacteria,COG3706@2|Bacteria,1PEI3@1224|Proteobacteria,43A7R@68525|delta/epsilon subdivisions,2X3SX@28221|Deltaproteobacteria,2YX14@29|Myxococcales	28221|Deltaproteobacteria	OT	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GGS1_k127_3596538_0	879212.DespoDRAFT_00794	6.772e-34	141.0	COG2191@1|root,COG2191@2|Bacteria,1RBNI@1224|Proteobacteria,42QZP@68525|delta/epsilon subdivisions,2WMY0@28221|Deltaproteobacteria,2MJH4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
GGS1_k127_3596538_1	1047013.AQSP01000109_gene2440	2.174e-17	88.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GGS1_k127_3596538_2	1125863.JAFN01000001_gene2800	5.983e-11	72.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
GGS1_k127_3598506_1	1004149.AFOE01000009_gene2171	0.0008038	46.0	COG2373@1|root,COG2373@2|Bacteria,4PKC4@976|Bacteroidetes	976|Bacteroidetes	J	this gene contains a nucleotide ambiguity which may be the result of a sequencing error	psrP1	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B,SprB
GGS1_k127_3598506_0	1227360.C176_13542	2.852e-21	99.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,26F48@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
GGS1_k127_3602611_0	1172180.KB911793_gene3554	0.000143	55.0	COG2909@1|root,COG2909@2|Bacteria,2GM1B@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GGS1_k127_3646565_1	926550.CLDAP_19690	3.726e-05	47.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GGS1_k127_3646565_0	1449126.JQKL01000003_gene1745	8.242e-164	531.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,267M9@186813|unclassified Clostridiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GGS1_k127_3646657_0	1173028.ANKO01000166_gene4289	6.1e-55	207.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_3646657_2	1174528.JH992898_gene2844	1.174e-15	88.0	COG0340@1|root,COG0340@2|Bacteria,1G5EQ@1117|Cyanobacteria,1JI7Y@1189|Stigonemataceae	1117|Cyanobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
GGS1_k127_3646657_1	419665.Maeo_0835	2.919e-16	84.0	COG3269@1|root,arCOG01641@2157|Archaea,2Y1N9@28890|Euryarchaeota,23R8T@183939|Methanococci	183939|Methanococci	S	PFAM Deoxyribonuclease rho motif-related TRAM	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GGS1_k127_3648194_1	653733.Selin_0667	3.245e-10	65.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GGS1_k127_3648194_0	1499968.TCA2_2767	1.671e-20	108.0	COG1361@1|root,COG2931@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GGS1_k127_3648584_0	439481.Aboo_0654	3.004e-85	310.0	arCOG00373@1|root,arCOG02452@1|root,arCOG00373@2157|Archaea,arCOG02452@2157|Archaea,2Y71H@28890|Euryarchaeota,3F35U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_3656877_0	673860.AciM339_0394	5.265e-05	51.0	arCOG05363@1|root,arCOG05363@2157|Archaea,2Y07M@28890|Euryarchaeota,3F2V9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GGS1_k127_3686774_0	439481.Aboo_0580	3.637e-92	312.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,3F2FE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Intein_splicing,LAGLIDADG_3,Radical_SAM
GGS1_k127_3686774_3	797209.ZOD2009_13336	0.0008612	50.0	COG1413@1|root,arCOG02966@2157|Archaea,2XVPV@28890|Euryarchaeota,23TWS@183963|Halobacteria	183963|Halobacteria	T	COG1413 FOG HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GGS1_k127_3686774_2	1034943.BN1094_00290	6.714e-23	116.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1JFDY@118969|Legionellales	118969|Legionellales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	rtxA2_1	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
GGS1_k127_3686774_1	234267.Acid_5209	4.078e-44	163.0	COG2987@1|root,COG2987@2|Bacteria,3Y2VD@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GGS1_k127_3686972_0	1210908.HSB1_22580	1.751e-91	320.0	COG1228@1|root,arCOG00696@2157|Archaea,2XWAY@28890|Euryarchaeota,23UGI@183963|Halobacteria	183963|Halobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GGS1_k127_3686972_3	756499.Desde_1822	1.748e-10	70.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,267A9@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GGS1_k127_3686972_1	330214.NIDE1127	1.372e-31	126.0	COG0492@1|root,COG0492@2|Bacteria,3J0M0@40117|Nitrospirae	40117|Nitrospirae	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
GGS1_k127_3702305_1	649638.Trad_2316	8.482e-55	205.0	COG0060@1|root,COG0060@2|Bacteria,1WI61@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GGS1_k127_3702305_0	1163730.FFONT_0935	5.794e-114	382.0	COG1167@1|root,arCOG00492@2157|Archaea,2XPUJ@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM Aminotransferase class I and II	agt	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GGS1_k127_3710312_0	673860.AciM339_1505	5.622e-86	299.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,3F2HN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	MCM OB domain	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
GGS1_k127_3716458_1	1223523.H340_02889	0.000179	51.0	COG0739@1|root,COG3021@1|root,COG0739@2|Bacteria,COG3021@2|Bacteria,2I9K6@201174|Actinobacteria	201174|Actinobacteria	D	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,RicinB_lectin_2,VCBS
GGS1_k127_3716458_0	1054217.TALC_00179	7.181e-118	404.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,241VX@183967|Thermoplasmata	183967|Thermoplasmata	L	HELICc2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2
GGS1_k127_3716545_3	511051.CSE_05380	4.158e-14	74.0	COG0136@1|root,COG0136@2|Bacteria	2|Bacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.2.1.11,1.2.1.12	ko:K00133,ko:K00134	ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010	M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552	R01061,R02291	RC00149,RC00684	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N,Semialdhyde_dh,Semialdhyde_dhC
GGS1_k127_3716545_1	304371.MCP_1545	1.206e-17	89.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GGS1_k127_3716545_0	304371.MCP_1283	7.628e-69	247.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2NBHA@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	3.4.21.62	ko:K01342	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
GGS1_k127_3716545_2	1121946.AUAX01000014_gene1229	1.468e-17	96.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria,4DMVA@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_3716545_4	69014.TK1304	4.815e-09	67.0	arCOG05849@1|root,arCOG05849@2157|Archaea,2Y3FG@28890|Euryarchaeota,243IT@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3718449_0	593750.Metfor_0316	1.209e-133	429.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
GGS1_k127_3718449_1	1094980.Mpsy_2508	1.727e-76	261.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
GGS1_k127_3718449_3	1157632.AQWQ01000006_gene285	7.461e-05	51.0	COG0346@1|root,COG0346@2|Bacteria,2IKRS@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_3718449_2	1054217.TALC_01541	6.52e-41	158.0	COG1772@1|root,arCOG04364@2157|Archaea,2XXJ6@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF531)	-	-	-	ko:K09725	-	-	-	-	ko00000	-	-	-	DUF531
GGS1_k127_3720854_0	269797.Mbar_A1866	5.045e-62	224.0	COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia	224756|Methanomicrobia	F	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
GGS1_k127_3724284_1	99598.Cal7507_2710	9.963e-12	80.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,1HMYH@1161|Nostocales	1117|Cyanobacteria	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
GGS1_k127_3724284_0	1457250.BBMO01000001_gene1581	5.869e-41	177.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_373040_1	1288494.EBAPG3_11150	1.242e-06	62.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria,37413@32003|Nitrosomonadales	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GGS1_k127_373040_0	673860.AciM339_0043	3.989e-19	92.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,3F2F3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GGS1_k127_3766050_0	926569.ANT_26870	4.662e-38	148.0	COG1432@1|root,COG1432@2|Bacteria,2G7FS@200795|Chloroflexi	200795|Chloroflexi	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GGS1_k127_3766050_1	1123508.JH636439_gene1132	5.532e-08	65.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
GGS1_k127_3774538_0	383372.Rcas_2277	4.461e-55	222.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
GGS1_k127_3774538_1	1206741.BAFX01000046_gene3230	1.666e-11	77.0	COG0382@1|root,COG0382@2|Bacteria,2HN87@201174|Actinobacteria,4G18D@85025|Nocardiaceae	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GGS1_k127_3779574_1	309807.SRU_2265	3.329e-05	51.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes	976|Bacteroidetes	P	K transport	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
GGS1_k127_3779574_0	237609.PSAKL28_52230	6.954e-40	168.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1GS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0475 Kef-type K transport systems, membrane components	IV02_22945	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
GGS1_k127_3779574_2	456320.Mvol_1478	0.0005401	43.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,23Q49@183939|Methanococci	183939|Methanococci	J	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GGS1_k127_3779978_1	28072.Nos7524_1655	2.528e-11	64.0	COG2402@1|root,COG2402@2|Bacteria,1G6FH@1117|Cyanobacteria,1HSJJ@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GGS1_k127_3779978_0	272844.PAB1903	9.33e-84	303.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,243BD@183968|Thermococci	183968|Thermococci	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GGS1_k127_3782489_2	1122138.AQUZ01000025_gene2797	0.0006868	52.0	COG1476@1|root,COG3903@1|root,COG1476@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
GGS1_k127_3782489_1	1173264.KI913950_gene4467	2.59e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
GGS1_k127_3782489_0	1121121.KB894301_gene2185	1.618e-27	115.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,26QIB@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GGS1_k127_378544_0	439481.Aboo_1089	4.988e-114	381.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,3F2IB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Intein_splicing,LAGLIDADG_3,RNA_pol_Rpb1_5
GGS1_k127_378544_4	1236689.MMALV_16410	5.03e-19	89.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,3F2SJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	rpl30e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
GGS1_k127_378544_3	1236689.MMALV_16400	2.233e-30	126.0	COG0195@1|root,arCOG01760@2157|Archaea,2Y6CH@28890|Euryarchaeota,3F2TQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5
GGS1_k127_378544_6	673860.AciM339_0010	6.304e-11	77.0	COG1361@1|root,arCOG01917@1|root,arCOG05791@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG04400@2157|Archaea,arCOG05791@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
GGS1_k127_378544_1	246200.SPO0571	9.128e-87	325.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_378544_2	1054217.TALC_01515	8.163e-43	165.0	COG0284@1|root,arCOG00081@2157|Archaea,2XU66@28890|Euryarchaeota,241PX@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GGS1_k127_378544_5	278963.ATWD01000002_gene720	4.275e-12	70.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria,2JHKB@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3797297_2	519442.Huta_2910	3.282e-09	69.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWHT@28890|Euryarchaeota,23V64@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	gntR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5,MarR_2
GGS1_k127_3797297_1	1267535.KB906767_gene3024	1.856e-16	83.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	frzZ	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GGS1_k127_3797297_3	195522.BD01_2032	1.891e-06	55.0	COG1412@1|root,arCOG04312@2157|Archaea,2XZ0Z@28890|Euryarchaeota,2441K@183968|Thermococci	183968|Thermococci	V	Fcf1	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	Fcf1
GGS1_k127_3797297_0	647113.Metok_0259	1.079e-163	527.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,23QPD@183939|Methanococci	183939|Methanococci	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,eIF2_C
GGS1_k127_3800405_0	439481.Aboo_0846	7.587e-150	486.0	COG0017@1|root,arCOG00407@2157|Archaea,2XTZJ@28890|Euryarchaeota,3F37W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	class II (D K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GGS1_k127_3800405_1	1459636.NTE_03059	1.57e-16	79.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3809303_0	1121405.dsmv_2608	1.733e-84	289.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
GGS1_k127_3809303_2	240015.ACP_0163	3.603e-11	70.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria,2JHKB@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3809303_1	1121405.dsmv_2612	8.005e-50	185.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GGS1_k127_3817544_1	483219.LILAB_15610	1.852e-05	57.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
GGS1_k127_3817544_0	443152.MDG893_02905	1.919e-45	187.0	COG2706@1|root,COG2931@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,1R0AU@1224|Proteobacteria,1S2TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_386143_0	565033.GACE_1477	5.485e-10	61.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,245Y7@183980|Archaeoglobi	183980|Archaeoglobi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GGS1_k127_3864314_0	926560.KE387023_gene1413	1.347e-11	78.0	COG3693@1|root,COG3828@1|root,COG3693@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_2,CBM_3,CBM_4_9,CBM_6,Glyco_hydro_10,Glyco_hydro_48,Ricin_B_lectin,VCBS,fn3
GGS1_k127_3864314_1	1192034.CAP_2557	1.968e-11	76.0	COG1657@1|root,COG1657@2|Bacteria,1MVWK@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GGS1_k127_3865355_3	1123226.KB899277_gene1522	4.02e-13	69.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,26RD7@186822|Paenibacillaceae	91061|Bacilli	O	Fe-S cluster assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GGS1_k127_3865355_1	383372.Rcas_0305	2.219e-30	136.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,375CG@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GGS1_k127_3865355_2	1229909.NSED_02490	2.189e-18	88.0	COG2146@1|root,arCOG02852@2157|Archaea,41T71@651137|Thaumarchaeota	651137|Thaumarchaeota	P	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
GGS1_k127_3865355_0	326424.FRAAL4559	2.512e-87	305.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4ERTT@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GGS1_k127_3869716_3	439481.Aboo_0507	2.545e-26	113.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,3F2FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
GGS1_k127_3869716_4	1459636.NTE_02691	1.815e-17	91.0	arCOG08673@1|root,arCOG08673@2157|Archaea	1459636.NTE_02691|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3869716_0	439481.Aboo_0660	1.034e-68	248.0	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,3F2X0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
GGS1_k127_3869716_2	926560.KE387023_gene1567	3.045e-48	188.0	COG0477@1|root,COG2814@2|Bacteria,1WMVG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GGS1_k127_3869716_5	543632.JOJL01000053_gene1507	2.07e-09	63.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
GGS1_k127_3869716_1	649638.Trad_1974	1.024e-65	238.0	COG0322@1|root,COG0322@2|Bacteria,1WJD8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
GGS1_k127_3869886_0	1054217.TALC_00911	6.175e-34	139.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,241N1@183967|Thermoplasmata	183967|Thermoplasmata	J	phenylalanine-tRNA ligase activity	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
GGS1_k127_3870967_0	1408473.JHXO01000015_gene1906	1.266e-15	92.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GGS1_k127_3881068_0	638303.Thal_1264	1.014e-128	423.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GGS1_k127_3881068_2	1536774.H70357_24970	6.189e-09	66.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,27010@186822|Paenibacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GGS1_k127_3881068_1	292459.STH1846	1.62e-25	112.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GGS1_k127_3894784_0	439481.Aboo_1545	1.338e-32	136.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota,3F328@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_3894784_1	1128421.JAGA01000002_gene1054	2.041e-29	125.0	COG1611@1|root,COG1611@2|Bacteria,2NPJB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
GGS1_k127_3894784_2	1104324.P186_2580	1.997e-06	58.0	COG1994@1|root,arCOG00614@2157|Archaea	2157|Archaea	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GGS1_k127_3917001_2	861299.J421_0542	2.638e-08	60.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GGS1_k127_3917001_1	880073.Calab_2101	2.435e-08	68.0	COG1361@1|root,COG2911@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
GGS1_k127_3917001_3	626418.bglu_2g06500	3.706e-08	68.0	COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,2VYUV@28216|Betaproteobacteria,1K5GN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3917001_4	991905.SL003B_3563	1.008e-06	63.0	COG4254@1|root,COG4254@2|Bacteria,1PPWK@1224|Proteobacteria,2TYY3@28211|Alphaproteobacteria,4BRH4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GGS1_k127_3917001_0	439481.Aboo_1226	5.965e-10	74.0	arCOG03256@1|root,arCOG03439@1|root,arCOG07760@1|root,arCOG03256@2157|Archaea,arCOG03439@2157|Archaea,arCOG07760@2157|Archaea,2Y704@28890|Euryarchaeota,3F320@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CUB,Peptidase_C25,Propeptide_C25
GGS1_k127_3920770_0	323259.Mhun_2284	3.194e-13	72.0	COG1997@1|root,arCOG04208@2157|Archaea,2XYWD@28890|Euryarchaeota,2N9ZP@224756|Methanomicrobia	224756|Methanomicrobia	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
GGS1_k127_3920770_2	1054217.TALC_00324	7.545e-10	60.0	COG1996@1|root,arCOG04341@2157|Archaea,2Y5VN@28890|Euryarchaeota	28890|Euryarchaeota	K	DNA directed RNA polymerase, 7 kDa subunit	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
GGS1_k127_3920770_1	768679.TTX_0825	8.636e-11	72.0	COG1382@1|root,arCOG01342@2157|Archaea,2XRFV@28889|Crenarchaeota	28889|Crenarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
GGS1_k127_3928562_1	118161.KB235922_gene3173	1.417e-24	118.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3VJ0W@52604|Pleurocapsales	1117|Cyanobacteria	K	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
GGS1_k127_3928562_2	40571.JOEA01000002_gene4928	1.406e-08	64.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4E3XG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3928562_0	926566.Terro_2902	4.954e-52	212.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_3942074_0	472759.Nhal_2969	7.536e-140	460.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GGS1_k127_3951801_0	1123360.thalar_01160	7.34e-69	257.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,2TYMP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GGS1_k127_3951801_1	272557.APE_2400.1	4.991e-66	244.0	COG0351@1|root,arCOG00020@2157|Archaea,2XPQB@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM Phosphomethylpyrimidine kinase	thiDN	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K21219,ko:K21220	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
GGS1_k127_3958109_0	644966.Tmar_1271	1.71e-43	170.0	COG1131@1|root,COG2386@1|root,COG1131@2|Bacteria,COG2386@2|Bacteria,1V7J1@1239|Firmicutes,24M9A@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GGS1_k127_3958109_2	268739.Nmlp_3372	2.556e-12	77.0	COG2386@1|root,arCOG01328@2157|Archaea,2XTAS@28890|Euryarchaeota,23W0C@183963|Halobacteria	183963|Halobacteria	O	ABC-type transport system permease protein 1 (Heme exporter protein B)	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GGS1_k127_3958109_1	1382356.JQMP01000004_gene238	2.963e-26	117.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GGS1_k127_3962509_4	710111.FraQA3DRAFT_4565	0.0003659	50.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4EU82@85013|Frankiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	ko:K14371	ko00522,ko01052,ko01130,map00522,map01052,map01130	M00777	R06480,R06481,R06482,R06483	RC00004,RC02913,RC02914,RC02915,RC02920,RC02921,RC02922,RC02923,RC02924,RC02925,RC02926,RC02927,RC02928,RC02929,RC02930	ko00000,ko00001,ko00002,ko01008	-	-	-	ADH_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
GGS1_k127_3962509_2	1324957.K933_10909	2.142e-38	154.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria	183963|Halobacteria	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA2	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
GGS1_k127_3962509_1	673860.AciM339_0296	4.952e-65	243.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,3F2M3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
GGS1_k127_3962509_3	521011.Mpal_1087	7.151e-32	145.0	COG3356@1|root,arCOG04351@2157|Archaea,2XVEY@28890|Euryarchaeota,2NAJK@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
GGS1_k127_3962509_0	673860.AciM339_0074	7.246e-122	402.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,3F2F9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Beta-Casp domain	epf1	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
GGS1_k127_3964348_0	589924.Ferp_0652	4.057e-65	234.0	COG0123@1|root,arCOG00324@2157|Archaea,2XT0B@28890|Euryarchaeota,246V5@183980|Archaeoglobi	183980|Archaeoglobi	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GGS1_k127_3964348_1	439481.Aboo_0802	3.267e-33	133.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
GGS1_k127_3970652_1	240015.ACP_2236	7.549e-63	247.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKIF@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_3970652_2	67315.JOBD01000023_gene310	2.129e-49	184.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
GGS1_k127_3970652_3	1150398.JIBJ01000008_gene625	3.046e-24	108.0	COG0346@1|root,COG0346@2|Bacteria,2IM43@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_3970652_0	673860.AciM339_1269	1.606e-214	694.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,3F2F0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA polymerase type-B family	polB1	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1,Intein_splicing
GGS1_k127_3973320_0	673860.AciM339_1241	7.944e-147	486.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota,3F2GV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH,HHH_3,Radical_SAM
GGS1_k127_3973320_2	1078085.HMPREF1210_02137	1.751e-18	96.0	COG1916@1|root,COG1916@2|Bacteria,1TSWJ@1239|Firmicutes,4HANT@91061|Bacilli,26DCS@186818|Planococcaceae	91061|Bacilli	S	TraB family	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
GGS1_k127_3973320_1	926550.CLDAP_28350	1.067e-24	120.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
GGS1_k127_3973320_3	673860.AciM339_0276	2.006e-10	66.0	arCOG13537@1|root,arCOG13537@2157|Archaea,2Y1U2@28890|Euryarchaeota,3F2T4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_397561_5	348780.NP_2390A	6.988e-19	93.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,23SS9@183963|Halobacteria	183963|Halobacteria	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
GGS1_k127_397561_4	439481.Aboo_0095	4.885e-28	122.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,3F2NI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GGS1_k127_397561_0	439481.Aboo_0094	2.221e-191	620.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,3F2F7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A0543	Anticodon_1,tRNA-synt_1g,tRNA_bind
GGS1_k127_397561_1	768672.Desfe_1144	7.914e-80	280.0	COG3199@1|root,arCOG01350@2157|Archaea,2XPMG@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM ATP-NAD AcoX kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
GGS1_k127_397561_2	1054217.TALC_00171	9.333e-58	219.0	COG3390@1|root,arCOG02258@2157|Archaea,2Y7QP@28890|Euryarchaeota,241WM@183967|Thermoplasmata	183967|Thermoplasmata	S	protein conserved in archaea	-	-	-	ko:K09746	-	-	-	-	ko00000	-	-	-	-
GGS1_k127_397561_3	1293048.CBMB010000001_gene544	2.043e-33	134.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,23RXQ@183963|Halobacteria	183963|Halobacteria	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	rpa1	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
GGS1_k127_3989736_0	673860.AciM339_1573	5.699e-87	294.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
GGS1_k127_3989736_1	443254.Marpi_0823	5.282e-15	89.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GGS1_k127_3994098_1	797304.Natgr_2836	2.556e-06	55.0	COG1325@1|root,arCOG01042@2157|Archaea,2Y01Q@28890|Euryarchaeota,23VKT@183963|Halobacteria	183963|Halobacteria	J	exosome subunit	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
GGS1_k127_3994098_0	1121920.AUAU01000005_gene961	2.156e-65	234.0	COG0477@1|root,COG2814@2|Bacteria,3Y711@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_3999489_1	1457250.BBMO01000001_gene1581	2.283e-68	265.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_3999489_2	204669.Acid345_0909	1.829e-59	236.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKYK@204432|Acidobacteriia	204669.Acid345_0909|-	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_3999489_3	926569.ANT_12670	5.745e-48	181.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GGS1_k127_3999489_0	1051632.TPY_3393	1.93e-76	271.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia	186801|Clostridia	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GGS1_k127_3999489_4	1459636.NTE_01234	1.141e-29	121.0	COG1013@1|root,arCOG01599@2157|Archaea,41SAB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GGS1_k127_4015947_2	1163617.SCD_n00024	6.258e-125	406.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
GGS1_k127_4015947_0	1234664.AMRO01000003_gene625	4.337e-194	627.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1WHXR@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.28	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R01505	RC00534	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GGS1_k127_4015947_1	330779.Saci_1483	1.158e-167	543.0	COG0174@1|root,arCOG01909@2157|Archaea,2XPM9@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM Glutamine synthetase, catalytic	glnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GGS1_k127_4019077_1	386456.JQKN01000001_gene2000	1.375e-07	64.0	arCOG12324@1|root,arCOG12324@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4019077_0	1333998.M2A_0881	8.45e-54	199.0	COG0189@1|root,COG4067@1|root,COG0189@2|Bacteria,COG4067@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria,4BT9Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Prokaryotic glutathione synthetase, ATP-grasp domain	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK,Zn_protease
GGS1_k127_4020368_0	273116.14324294	2.588e-46	176.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,241PN@183967|Thermoplasmata	183967|Thermoplasmata	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GGS1_k127_4020368_2	273116.14324406	1.086e-07	63.0	COG0640@1|root,arCOG05349@2157|Archaea,2XYUG@28890|Euryarchaeota,241TE@183967|Thermoplasmata	183967|Thermoplasmata	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4020368_3	439481.Aboo_1326	3.469e-07	58.0	arCOG05352@1|root,arCOG05352@2157|Archaea,2Y75N@28890|Euryarchaeota,3F3FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4020368_1	1276756.AUEX01000018_gene2992	1.057e-26	110.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,4AA75@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
GGS1_k127_4022393_1	1041930.Mtc_0582	2.787e-54	203.0	COG1916@1|root,arCOG02142@2157|Archaea,2XTNE@28890|Euryarchaeota,2N97A@224756|Methanomicrobia	224756|Methanomicrobia	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
GGS1_k127_4022393_2	439481.Aboo_0715	5.289e-36	143.0	arCOG02452@1|root,arCOG02452@2157|Archaea,2Y71S@28890|Euryarchaeota,3F36K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	COG0467 RecA-superfamily ATPases implicated in signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4022393_0	439481.Aboo_0716	5.301e-66	236.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTU3@28890|Euryarchaeota,3F31P@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Rad51	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_4046341_0	1121472.AQWN01000010_gene559	8.576e-203	644.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,260B9@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GGS1_k127_4046739_2	589924.Ferp_2433	6.845e-14	74.0	arCOG02836@1|root,arCOG02836@2157|Archaea,2XYP5@28890|Euryarchaeota,246CW@183980|Archaeoglobi	183980|Archaeoglobi	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4046739_0	694429.Pyrfu_0402	2.959e-124	411.0	COG2046@1|root,arCOG04191@2157|Archaea,2XPTX@28889|Crenarchaeota	28889|Crenarchaeota	H	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
GGS1_k127_4046739_1	565033.GACE_1147	2.465e-117	390.0	COG3379@1|root,arCOG01377@2157|Archaea,2XU9G@28890|Euryarchaeota,245NN@183980|Archaeoglobi	183980|Archaeoglobi	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GGS1_k127_4052325_0	673860.AciM339_0562	2.222e-25	115.0	COG0524@1|root,arCOG00014@2157|Archaea,2XU7Z@28890|Euryarchaeota,3F2PY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	pfkB family carbohydrate kinase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.1.213,2.7.1.73	ko:K22026	ko00230,ko00240,map00230,map00240	-	R00513,R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A2903	PfkB
GGS1_k127_4061357_0	35754.JNYJ01000011_gene781	3.685e-12	80.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria,4DBYK@85008|Micromonosporales	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C,Pectate_lyase_3
GGS1_k127_4061357_2	1306990.BARG01000033_gene3861	0.0003148	54.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C
GGS1_k127_4061357_1	314285.KT71_00915	1.003e-05	50.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1J4PY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
GGS1_k127_4095475_3	673860.AciM339_1270	4.314e-42	162.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,3F2ZF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	flaJ	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
GGS1_k127_4095475_0	192952.MM_0048	9.695e-174	558.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,2NA9G@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Aldehyde dehydrogenase	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
GGS1_k127_4095475_1	439481.Aboo_0029	1.072e-51	191.0	COG2220@1|root,arCOG00497@2157|Archaea,2XZBG@28890|Euryarchaeota,3F2Q1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GGS1_k127_4095475_2	304371.MCP_0011	9.207e-48	179.0	COG1976@1|root,arCOG04176@2157|Archaea,2XU7N@28890|Euryarchaeota,2N9JT@224756|Methanomicrobia	224756|Methanomicrobia	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
GGS1_k127_4096624_3	272844.PAB0882	8.789e-21	98.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,2443K@183968|Thermococci	183968|Thermococci	V	ribonuclease activity	nob1	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
GGS1_k127_4096624_0	1229909.NSED_08200	1.27e-128	422.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GGS1_k127_4096624_4	1445613.JALM01000035_gene398	9.718e-07	62.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4E2RA@85010|Pseudonocardiales	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
GGS1_k127_4096624_2	649747.HMPREF0083_01383	1.666e-83	284.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,275PE@186822|Paenibacillaceae	91061|Bacilli	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GGS1_k127_4096624_1	673860.AciM339_0631	1.533e-91	305.0	COG0020@1|root,arCOG01532@2157|Archaea,2XSW1@28890|Euryarchaeota,3F2F2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
GGS1_k127_4105521_1	313612.L8106_07771	1.163e-26	126.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	csbX	-	-	-	-	-	-	-	-	-	-	iYL1228.KPN_02541	MFS_1
GGS1_k127_4105521_0	877414.ATWA01000003_gene360	6.947e-57	210.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,267IS@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GGS1_k127_4133172_1	439481.Aboo_0741	8.269e-10	66.0	COG1672@1|root,COG3398@1|root,arCOG02611@2157|Archaea,arCOG03166@2157|Archaea	2157|Archaea	K	ATPase, AAA superfamily	deoR2	-	3.6.4.12,4.2.3.1,6.3.4.15	ko:K01733,ko:K02039,ko:K03436,ko:K03524,ko:K03655	ko00260,ko00750,ko00780,ko01100,ko01110,ko01120,ko01230,ko03440,map00260,map00750,map00780,map01100,map01110,map01120,map01230,map03440	M00018	R01074,R01466,R05086,R05145	RC00017,RC00043,RC00070,RC00096,RC00526,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400	-	-	-	BPL_C,BPL_LplA_LipB,DeoRC,HTH_11,HTH_24,HTH_DeoR,MarR_2,PhoU
GGS1_k127_4133172_0	1131269.AQVV01000005_gene376	3.962e-10	66.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GGS1_k127_4140106_0	671143.DAMO_2896	1.704e-76	286.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GGS1_k127_414439_1	999630.TUZN_0679	6.017e-14	78.0	COG1052@1|root,arCOG01755@2157|Archaea,2XPN8@28889|Crenarchaeota	28889|Crenarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GGS1_k127_414439_0	913865.DOT_4826	1.094e-58	217.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,260R6@186807|Peptococcaceae	186801|Clostridia	C	NADH dehydrogenase	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GGS1_k127_4147239_0	1211115.ALIQ01000156_gene4412	7.248e-80	286.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3NCSX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
GGS1_k127_4148781_0	1125863.JAFN01000001_gene1835	5e-119	397.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GGS1_k127_4148781_2	439235.Dalk_2289	0.0003788	54.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
GGS1_k127_4153871_0	1038869.AXAN01000037_gene1605	1.156e-234	736.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VNNI@28216|Betaproteobacteria,1K3QF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GGS1_k127_4157436_1	1047013.AQSP01000122_gene2223	1.287e-06	62.0	COG3291@1|root,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CHU_C,FlgD_ig,Glyco_hydro_6,PKD,VCBS
GGS1_k127_4157436_0	266117.Rxyl_0169	7.641e-14	80.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GGS1_k127_4170916_0	1236689.MMALV_13600	9.246e-85	298.0	COG0044@1|root,arCOG00689@2157|Archaea,2XTQU@28890|Euryarchaeota,3F2JE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GGS1_k127_4170916_1	224325.AF_1332	8.394e-06	56.0	COG1711@1|root,arCOG00551@2157|Archaea,2XYKZ@28890|Euryarchaeota,246AC@183980|Archaeoglobi	183980|Archaeoglobi	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
GGS1_k127_4173025_0	1242864.D187_002404	8.601e-79	274.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
GGS1_k127_4173025_1	382464.ABSI01000010_gene3269	3.396e-74	270.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	doeB	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
GGS1_k127_4193036_0	1382304.JNIL01000001_gene2342	2.497e-71	254.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,278XT@186823|Alicyclobacillaceae	91061|Bacilli	C	Electron transfer flavoprotein FAD-binding domain	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GGS1_k127_4193036_1	931277.C448_12446	2.11e-07	63.0	arCOG04629@1|root,arCOG04629@2157|Archaea,2XYMK@28890|Euryarchaeota,23WZZ@183963|Halobacteria	183963|Halobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GGS1_k127_4193036_2	247490.KSU1_C0750	4.862e-05	52.0	COG2405@1|root,COG2405@2|Bacteria,2J4UV@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4193841_1	1457250.BBMO01000001_gene1581	6.325e-50	198.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_4193841_0	529709.PYCH_04140	4.546e-59	224.0	COG1668@1|root,arCOG01462@2157|Archaea,2XX4X@28890|Euryarchaeota,242TZ@183968|Thermococci	183968|Thermococci	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GGS1_k127_4193841_2	69014.TK1337	2.972e-19	89.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWV8@28890|Euryarchaeota,242K1@183968|Thermococci	183968|Thermococci	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_4211963_0	573063.Metin_0043	5.061e-229	722.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,23QF3@183939|Methanococci	183939|Methanococci	O	Cell division protein 48, CDC48, domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
GGS1_k127_4218257_4	1450694.BTS2_1361	9.053e-13	79.0	COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,1ZDNA@1386|Bacillus	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GGS1_k127_4218257_1	338963.Pcar_1292	1.337e-67	236.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,43SE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GGS1_k127_4218257_0	1236689.MMALV_01900	1.412e-94	322.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GGS1_k127_4218257_2	1236689.MMALV_15580	3.69e-43	162.0	COG0184@1|root,arCOG04185@2157|Archaea,2XWKV@28890|Euryarchaeota,3F2PA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal S13/S15 N-terminal domain	rps15	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
GGS1_k127_4218257_3	192952.MM_1970	4.582e-30	134.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,2N99F@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
GGS1_k127_4231507_3	1094980.Mpsy_1210	1.933e-16	85.0	COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,2NAQX@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
GGS1_k127_4231507_1	1459636.NTE_01712	2.449e-51	206.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	ubiE	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GGS1_k127_4231507_0	519442.Huta_1420	1.408e-52	190.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWV8@28890|Euryarchaeota,23YZM@183963|Halobacteria	183963|Halobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GGS1_k127_423424_0	1125863.JAFN01000001_gene2220	2.346e-192	621.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GGS1_k127_423424_1	97138.C820_01434	1.635e-107	366.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.17.1.9,1.4.1.13,1.4.1.14	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	-	R00093,R00114,R00248,R00519	RC00006,RC00010,RC02796,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GGS1_k127_4241078_0	283699.D172_2721	1.22e-17	99.0	COG0824@1|root,COG2931@1|root,COG3210@1|root,COG3637@1|root,COG5625@1|root,COG0824@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria,COG5625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2Q11U@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	MQU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_5,Cadherin_3,He_PIG,OMP_b-brl,OmpA_membrane,fn3
GGS1_k127_4244643_4	679926.Mpet_0861	1.832e-05	55.0	COG3398@1|root,arCOG02611@2157|Archaea	679926.Mpet_0861|-	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4244643_2	439481.Aboo_0550	1.008e-80	278.0	COG0467@1|root,arCOG01171@2157|Archaea,2XYM8@28890|Euryarchaeota,3F38P@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_4244643_1	509191.AEDB02000051_gene1333	2.12e-89	324.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,3WGD0@541000|Ruminococcaceae	186801|Clostridia	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GGS1_k127_4244643_0	439481.Aboo_0430	6.248e-136	439.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,3F2HE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Intein_splicing,Rad51
GGS1_k127_4244643_3	797209.ZOD2009_08199	6.826e-06	56.0	COG3413@1|root,arCOG02276@2157|Archaea,2XUEQ@28890|Euryarchaeota,23UC6@183963|Halobacteria	183963|Halobacteria	K	Bacterio-opsin activator HTH	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
GGS1_k127_4246708_3	1283299.AUKG01000001_gene1984	5.522e-22	104.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GGS1_k127_4246708_1	1459636.NTE_02661	7.606e-35	154.0	COG1254@1|root,arCOG00643@2157|Archaea	2157|Archaea	C	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Acylphosphatase
GGS1_k127_4246708_0	263820.PTO0597	2.019e-40	157.0	COG2095@1|root,arCOG01997@2157|Archaea,2XZEI@28890|Euryarchaeota,2426E@183967|Thermoplasmata	183967|Thermoplasmata	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
GGS1_k127_4246708_4	1125863.JAFN01000001_gene1812	1.108e-09	71.0	COG1520@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,1N8Z7@1224|Proteobacteria,43AIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
GGS1_k127_4246708_2	479434.Sthe_2627	5.591e-34	148.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,27Y3V@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GGS1_k127_4273388_2	369723.Strop_0210	6.484e-05	54.0	COG3210@1|root,COG3210@2|Bacteria,2IEWP@201174|Actinobacteria	201174|Actinobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4273388_0	1349822.NSB1T_03270	1.389e-38	162.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22XX8@171551|Porphyromonadaceae	976|Bacteroidetes	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GGS1_k127_4273388_1	1121479.AUBS01000002_gene3633	9.514e-24	117.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
GGS1_k127_4286837_0	1463825.JNXC01000053_gene24	1.242e-09	71.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,Ricin_B_lectin,ThuA
GGS1_k127_428847_1	47716.JOFH01000023_gene3660	2.366e-14	85.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GGS1_k127_428847_0	1120973.AQXL01000121_gene68	6.092e-69	251.0	COG0477@1|root,COG2814@2|Bacteria,1TPPY@1239|Firmicutes,4HNJ9@91061|Bacilli,27A8T@186823|Alicyclobacillaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GGS1_k127_4309514_0	76114.ebA5355	4.803e-119	388.0	COG1977@1|root,COG2414@1|root,COG1977@2|Bacteria,COG2414@2|Bacteria,1NQ92@1224|Proteobacteria,2W044@28216|Betaproteobacteria,2KY26@206389|Rhodocyclales	206389|Rhodocyclales	CH	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AFOR_C,AFOR_N,ThiS
GGS1_k127_4309514_2	1054217.TALC_00032	1.776e-10	68.0	arCOG15031@1|root,arCOG15031@2157|Archaea,2Y4G8@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4309514_1	1054217.TALC_00503	1.702e-55	202.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,241RJ@183967|Thermoplasmata	183967|Thermoplasmata	K	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
GGS1_k127_4325702_0	1173025.GEI7407_1314	3.272e-108	368.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1G03V@1117|Cyanobacteria,1H7B2@1150|Oscillatoriales	1117|Cyanobacteria	CE	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
GGS1_k127_4333005_0	452637.Oter_0946	1.135e-78	277.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,46U7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA
GGS1_k127_4333005_3	1163617.SCD_n01862	4.125e-53	192.0	COG0745@1|root,COG0745@2|Bacteria,1MZ03@1224|Proteobacteria	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GGS1_k127_4333005_4	1121945.ATXS01000004_gene1074	2.184e-40	164.0	COG0704@1|root,arCOG00318@2157|Archaea,2XT7D@28890|Euryarchaeota,23SX0@183963|Halobacteria	183963|Halobacteria	K	Phosphate uptake regulator	phoU5	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
GGS1_k127_4333005_1	1033806.HTIA_0600	3.12e-77	271.0	COG3407@1|root,arCOG02937@2157|Archaea,2XUJ7@28890|Euryarchaeota,23T1T@183963|Halobacteria	183963|Halobacteria	I	COG3407 Mevalonate pyrophosphate decarboxylase	mvaD	-	4.1.1.99	ko:K17942	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10561	RC00453	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GGS1_k127_4333005_2	717231.Flexsi_1879	1.615e-62	229.0	COG0672@1|root,COG0672@2|Bacteria,2GGKP@200930|Deferribacteres	200930|Deferribacteres	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
GGS1_k127_4345197_2	1134413.ANNK01000012_gene1703	2.487e-17	88.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,4HJ9Q@91061|Bacilli,1ZGXH@1386|Bacillus	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GGS1_k127_4345197_3	1122137.AQXF01000002_gene118	3.145e-09	63.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GGS1_k127_4345197_1	1236689.MMALV_01990	3.319e-68	257.0	COG1005@1|root,arCOG01546@2157|Archaea,2XT7N@28890|Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase subunit 1 (Chain H)	nuoH	-	1.5.98.3,1.6.5.3	ko:K00337,ko:K22163	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	NADHdh
GGS1_k127_4345197_0	237368.SCABRO_02007	1.691e-90	308.0	COG0649@1|root,COG0649@2|Bacteria,2IY7J@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GGS1_k127_4367842_0	673860.AciM339_0142	9.178e-126	416.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F32D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GGS1_k127_4372898_1	1382306.JNIM01000001_gene107	8.654e-09	65.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,zinc_ribbon_2
GGS1_k127_4372898_0	263358.VAB18032_27046	4.062e-100	346.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DA29@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GGS1_k127_4384561_0	485918.Cpin_4113	1.351e-20	109.0	COG2911@1|root,COG2911@2|Bacteria,4NHHA@976|Bacteroidetes,1IVM6@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG
GGS1_k127_4414473_1	1380356.JNIK01000013_gene4321	2.357e-36	141.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GGS1_k127_4414473_0	1379698.RBG1_1C00001G0452	7.733e-106	352.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
GGS1_k127_4414473_2	797114.C475_10794	8.643e-14	81.0	COG1575@1|root,arCOG00480@2157|Archaea,2XTKC@28890|Euryarchaeota,23SID@183963|Halobacteria	183963|Halobacteria	H	1,4-dihydroxy-2-naphthoate octaprenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GGS1_k127_4420172_1	1054217.TALC_00020	1.916e-47	186.0	COG1395@1|root,arCOG04152@2157|Archaea,2XTMG@28890|Euryarchaeota,241RI@183967|Thermoplasmata	183967|Thermoplasmata	K	DNA-binding transcription factor activity	-	-	-	ko:K07728	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GGS1_k127_4420172_0	1236689.MMALV_00300	8.777e-48	191.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,3F2U2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	tRNA intron endonuclease, catalytic C-terminal domain	endA	GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
GGS1_k127_442044_0	268739.Nmlp_2650	3.999e-21	110.0	COG1361@1|root,COG1470@1|root,COG3291@1|root,arCOG03612@1|root,arCOG04500@1|root,arCOG07554@1|root,arCOG02081@2157|Archaea,arCOG02089@2157|Archaea,arCOG02510@2157|Archaea,arCOG03612@2157|Archaea,arCOG04500@2157|Archaea,arCOG07554@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4426572_1	1121945.ATXS01000001_gene2309	9.664e-18	91.0	COG3413@1|root,arCOG02272@2157|Archaea,2Y7SJ@28890|Euryarchaeota,240WI@183963|Halobacteria	183963|Halobacteria	K	Bacterio-opsin activator HTH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_10
GGS1_k127_4426572_0	1298858.AUEL01000007_gene2306	3.119e-46	173.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,2UA4T@28211|Alphaproteobacteria,43KEQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
GGS1_k127_4426572_2	1342299.Z947_888	8.304e-06	59.0	2BVTZ@1|root,31ABS@2|Bacteria,1R1C7@1224|Proteobacteria,2TZ00@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4426572_3	1444309.JAQG01000099_gene4922	0.0009145	52.0	2EC1D@1|root,3360J@2|Bacteria,1VN3Y@1239|Firmicutes,4HR2I@91061|Bacilli,273UY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4435029_1	1123228.AUIH01000092_gene552	5.046e-24	119.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4435029_0	604354.TSIB_0965	1.456e-66	247.0	COG1672@1|root,arCOG03166@2157|Archaea,2XTP2@28890|Euryarchaeota,242XG@183968|Thermococci	183968|Thermococci	K	ATPase, AAA superfamily	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_5,HTH_IclR
GGS1_k127_4438432_6	696747.NIES39_A03260	6.839e-20	104.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GGS1_k127_4438432_8	870187.Thini_1774	8.926e-11	75.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GGS1_k127_4438432_9	118168.MC7420_4825	1.77e-06	59.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,1H7DH@1150|Oscillatoriales	1117|Cyanobacteria	M	Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BON,OmpA
GGS1_k127_4438432_7	42256.RradSPS_0568	4.088e-18	90.0	COG1917@1|root,COG1917@2|Bacteria,2GWWK@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GGS1_k127_4438432_1	673860.AciM339_0595	8.218e-82	286.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,3F2JJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the peptidase M24B family	pepQ1	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GGS1_k127_4438432_5	373994.Riv7116_0975	5.842e-30	127.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,1HNIS@1161|Nostocales	1117|Cyanobacteria	S	ADP-ribosylation factor family	-	-	-	-	-	-	-	-	-	-	-	-	Ras,Roc
GGS1_k127_4438432_2	304371.MCP_1553	1.655e-79	276.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,2N9ED@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GGS1_k127_4438432_3	439481.Aboo_0831	9.932e-47	180.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,3F2KR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
GGS1_k127_4438432_4	593117.TGAM_1324	2.608e-40	164.0	COG1041@1|root,arCOG00047@2157|Archaea,2XTD6@28890|Euryarchaeota,2434W@183968|Thermococci	183968|Thermococci	J	N-6 DNA Methylase	-	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
GGS1_k127_4438432_0	69014.TK0929	4.638e-135	443.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,242S6@183968|Thermococci	183968|Thermococci	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
GGS1_k127_4438918_0	1034943.BN1094_00290	1.973e-10	70.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1JFDY@118969|Legionellales	118969|Legionellales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	rtxA2_1	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
GGS1_k127_4439310_0	529709.PYCH_12150	6.663e-50	193.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
GGS1_k127_4439310_1	1209989.TepiRe1_0744	1.097e-43	170.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,42FR5@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
GGS1_k127_4439310_2	471854.Dfer_2050	3.972e-28	133.0	COG2831@1|root,COG2931@1|root,COG2831@2|Bacteria,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
GGS1_k127_444243_0	1121945.ATXS01000019_gene933	1.362e-88	308.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria	183963|Halobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GGS1_k127_4448788_0	1379698.RBG1_1C00001G1790	4.905e-117	388.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,OprB,SLH
GGS1_k127_4448788_1	1041930.Mtc_2006	6.798e-32	138.0	COG1404@1|root,COG1470@1|root,arCOG00702@2157|Archaea,arCOG02081@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
GGS1_k127_4459878_1	1236689.MMALV_06180	1.39e-14	81.0	arCOG01806@1|root,arCOG01806@2157|Archaea,2Y0PI@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
GGS1_k127_4459878_0	644966.Tmar_0539	8.28e-151	491.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GGS1_k127_4482049_0	309801.trd_1303	7.983e-86	297.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27XZ4@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GGS1_k127_4482049_1	593750.Metfor_0801	2.922e-70	246.0	COG0379@1|root,arCOG04459@2157|Archaea,2XUGT@28890|Euryarchaeota,2NABJ@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GGS1_k127_4505106_4	1219031.BBJR01000038_gene3131	2.004e-06	59.0	COG1622@1|root,COG2132@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria,4AGYB@80864|Comamonadaceae	28216|Betaproteobacteria	CQ	Copper binding proteins, plastocyanin/azurin family	nirK	-	1.3.3.5,1.7.2.1	ko:K00368,ko:K08100	ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120	M00529	R00783,R00785,R02394	RC00086,RC01983	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrome_CBB3
GGS1_k127_4505106_2	273116.14324332	6.42e-17	89.0	COG1308@1|root,arCOG04061@2157|Archaea,2XXYV@28890|Euryarchaeota,241VM@183967|Thermoplasmata	183967|Thermoplasmata	J	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
GGS1_k127_4505106_0	1220534.B655_0469	5.472e-66	237.0	COG0157@1|root,arCOG01482@2157|Archaea,2XTTY@28890|Euryarchaeota,23NNA@183925|Methanobacteria	183925|Methanobacteria	H	Involved in the catabolism of quinolinic acid (QA)	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GGS1_k127_4505106_3	861299.J421_0120	3.387e-13	83.0	COG3291@1|root,COG3325@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.1.3.5,3.2.1.14	ko:K01081,ko:K01183,ko:K20276	ko00230,ko00240,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18	-	F5_F8_type_C,Glyco_hydro_18,NPCBM_assoc,PKD,PPC,Trypsin_2,fn3
GGS1_k127_4505106_1	485916.Dtox_1611	1.3e-24	107.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GGS1_k127_451412_1	234267.Acid_7022	3.388e-09	70.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GGS1_k127_451412_0	717606.PaecuDRAFT_2033	1.834e-51	208.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GGS1_k127_452365_1	593750.Metfor_0146	4.096e-77	261.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
GGS1_k127_452365_2	593750.Metfor_0145	2.016e-31	133.0	COG0852@1|root,arCOG01551@2157|Archaea,2XZK1@28890|Euryarchaeota,2NA35@224756|Methanomicrobia	224756|Methanomicrobia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.5.98.3	ko:K22160	-	-	-	-	ko00000,ko01000	3.D.9.1	-	-	Complex1_30kDa
GGS1_k127_452365_0	593750.Metfor_0144	1.446e-115	388.0	COG3261@1|root,arCOG01547@2157|Archaea,2Y7K6@28890|Euryarchaeota,2N9MK@224756|Methanomicrobia	224756|Methanomicrobia	C	Membrane bound hydrogenase subunit	-	-	1.12.7.2	ko:K18016	-	-	R00019	-	ko00000,ko01000	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
GGS1_k127_4533994_1	604354.TSIB_1322	4.402e-51	189.0	COG0528@1|root,arCOG00858@2157|Archaea,2XT3U@28890|Euryarchaeota,242XX@183968|Thermococci	183968|Thermococci	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GGS1_k127_4533994_0	673860.AciM339_1206	9.971e-115	383.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
GGS1_k127_4536777_0	1236689.MMALV_14300	6.441e-59	214.0	arCOG04990@1|root,arCOG04990@2157|Archaea,2XYVI@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function TPD sequence-motif	-	-	-	-	-	-	-	-	-	-	-	-	TPD
GGS1_k127_4536777_1	1054217.TALC_00277	3.672e-53	196.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,241NH@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
GGS1_k127_4540834_0	1125863.JAFN01000001_gene1889	5.564e-43	181.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GGS1_k127_4542761_1	1040989.AWZU01000001_gene5481	6.137e-07	57.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_4542761_0	453591.Igni_1099	1.041e-23	108.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQZ7@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GGS1_k127_4542761_2	106370.Francci3_4194	1.359e-06	60.0	COG2230@1|root,COG2230@2|Bacteria,2I4EE@201174|Actinobacteria	201174|Actinobacteria	M	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GGS1_k127_4548064_0	304371.MCP_0354	1.069e-20	105.0	COG2202@1|root,arCOG06515@2157|Archaea,arCOG06918@2157|Archaea,2Y7SW@28890|Euryarchaeota,2NB2A@224756|Methanomicrobia	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GGS1_k127_4548064_1	439481.Aboo_1103	9.14e-15	85.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,3F2ID@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	helicase superfamily c-terminal domain	hef	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C,ResIII
GGS1_k127_4555956_1	1123388.AQWU01000067_gene680	1.753e-16	83.0	COG0662@1|root,COG0662@2|Bacteria,1WK83@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GGS1_k127_4555956_0	1459636.NTE_00644	4.16e-20	97.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4555956_2	935948.KE386494_gene350	4.454e-16	83.0	COG1247@1|root,COG1247@2|Bacteria,1UHYR@1239|Firmicutes,24H0A@186801|Clostridia,42G6C@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_4567478_3	797302.Halru_0220	0.0006493	49.0	COG1545@1|root,COG3425@1|root,arCOG01285@2157|Archaea,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23TJ1@183963|Halobacteria	183963|Halobacteria	I	COG3425 3-hydroxy-3-methylglutaryl CoA synthase	acaA	-	2.3.3.10	ko:K01641,ko:K07068	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
GGS1_k127_4567478_0	1121430.JMLG01000002_gene1078	3.926e-125	414.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GGS1_k127_4567478_2	218491.ECA4063	3.133e-32	136.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1MSJ1@122277|Pectobacterium	1236|Gammaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GGS1_k127_4567478_1	861299.J421_5582	1.456e-71	252.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GGS1_k127_4576183_0	549.BW31_04691	4.522e-09	70.0	COG2373@1|root,COG2911@1|root,COG4254@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG4254@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria,3VXVZ@53335|Pantoea	1236|Gammaproteobacteria	M	PFAM FecR protein	yeeJ	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
GGS1_k127_4588701_0	1242864.D187_006025	4.19e-16	94.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
GGS1_k127_4590738_1	573569.F7308_0648	2.162e-21	100.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GGS1_k127_4590738_0	224719.Abm4_0926	9.318e-60	218.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,23NJV@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
GGS1_k127_4590738_2	765952.PUV_18860	2.228e-12	81.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF285,PKD
GGS1_k127_4596941_1	63737.Npun_F0183	2.829e-15	89.0	COG2931@1|root,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
GGS1_k127_4596941_0	562970.Btus_3137	1.399e-72	258.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4HFM3@91061|Bacilli,2781W@186823|Alicyclobacillaceae	91061|Bacilli	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GGS1_k127_4596941_2	1123322.KB904652_gene483	2.728e-08	67.0	COG0454@1|root,COG0454@2|Bacteria,2H2PG@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GGS1_k127_4599481_1	1121937.AUHJ01000028_gene930	9.298e-13	82.0	COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	LM	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
GGS1_k127_4599481_3	647113.Metok_1161	4.768e-05	52.0	arCOG05149@1|root,arCOG05149@2157|Archaea,2Y4ZG@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4599481_0	867845.KI911784_gene1447	4.923e-30	127.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
GGS1_k127_4599481_2	56110.Oscil6304_3156	7.113e-06	58.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H9XU@1150|Oscillatoriales	1117|Cyanobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
GGS1_k127_4606644_0	673860.AciM339_0958	2.521e-148	499.0	COG0008@1|root,arCOG04302@2157|Archaea,2XSYV@28890|Euryarchaeota,3F2HK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
GGS1_k127_4606644_2	192952.MM_1767	6.224e-56	220.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2N97R@224756|Methanomicrobia	224756|Methanomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GGS1_k127_4606644_1	1054217.TALC_01360	6.705e-93	318.0	COG1304@1|root,arCOG00613@2157|Archaea,2XT6H@28890|Euryarchaeota,241IE@183967|Thermoplasmata	183967|Thermoplasmata	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
GGS1_k127_4611512_2	178306.PAE3638	6.455e-11	65.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2XSQD@28889|Crenarchaeota	28889|Crenarchaeota	S	SMART zinc finger, RanBP2-type	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,UPF0547,zinc_ribbon_2
GGS1_k127_4611512_0	1408422.JHYF01000006_gene1124	2.314e-74	263.0	COG1594@1|root,COG1594@2|Bacteria,1UHVH@1239|Firmicutes,25E4D@186801|Clostridia,36INV@31979|Clostridiaceae	186801|Clostridia	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4611512_1	391623.TERMP_00331	3.633e-36	147.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,243NV@183968|Thermococci	183968|Thermococci	L	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GGS1_k127_4622687_0	348780.NP_4750A	4.92e-36	153.0	COG1520@1|root,arCOG02556@2157|Archaea,2Y7US@28890|Euryarchaeota,240XF@183963|Halobacteria	183963|Halobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GGS1_k127_4622687_1	694429.Pyrfu_0043	8.289e-09	62.0	COG0237@1|root,arCOG01045@2157|Archaea,2XQTJ@28889|Crenarchaeota	28889|Crenarchaeota	F	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17,AAA_18
GGS1_k127_4624411_0	749927.AMED_5784	0.0002413	53.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DZ55@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC
GGS1_k127_4639526_0	235985.BBPN01000033_gene35	5.8e-11	77.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
GGS1_k127_4644861_1	1267534.KB906755_gene4053	4.286e-19	93.0	COG1032@1|root,COG1032@2|Bacteria,3Y3N8@57723|Acidobacteria,2JMAC@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GGS1_k127_4644861_2	357808.RoseRS_1367	0.0001969	49.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GGS1_k127_4648888_0	439481.Aboo_1389	2.286e-135	448.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,3F2FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
GGS1_k127_4648888_2	348780.NP_4310A	1.689e-14	74.0	COG2126@1|root,arCOG04126@2157|Archaea,2XZUV@28890|Euryarchaeota,23XE9@183963|Halobacteria	183963|Halobacteria	J	binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
GGS1_k127_4648888_3	1236689.MMALV_13580	3.432e-13	75.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,3F2SB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
GGS1_k127_4648888_1	644966.Tmar_0814	1.381e-17	92.0	COG2217@1|root,COG2217@2|Bacteria,1VJJE@1239|Firmicutes	1239|Firmicutes	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4648888_4	388467.A19Y_2739	3.695e-08	62.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
GGS1_k127_4648995_2	416591.Tlet_1306	2.598e-55	212.0	COG2866@1|root,COG2866@2|Bacteria,2GDXY@200918|Thermotogae	200918|Thermotogae	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GGS1_k127_4648995_0	453591.Igni_0261	1.445e-170	548.0	COG0119@1|root,arCOG02093@2157|Archaea,2XPZC@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM pyruvate carboxyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
GGS1_k127_4648995_1	498761.HM1_1471	2.316e-170	567.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,25F02@186801|Clostridia	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GGS1_k127_4648995_3	646529.Desaci_3047	1.589e-48	184.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GGS1_k127_4648995_4	1449351.RISW2_19880	4.948e-06	57.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2U79E@28211|Alphaproteobacteria,4KMK1@93682|Roseivivax	28211|Alphaproteobacteria	O	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
GGS1_k127_4667594_0	673860.AciM339_0753	5.718e-63	237.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
GGS1_k127_4667594_1	1094980.Mpsy_2612	4.557e-16	88.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
GGS1_k127_4670693_0	1267600.JFGT01000002_gene231	4.571e-15	89.0	COG2373@1|root,COG2911@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria,3VXVZ@53335|Pantoea	1236|Gammaproteobacteria	M	PFAM FecR protein	yeeJ	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
GGS1_k127_4670693_1	1226994.AMZB01000136_gene5045	3.204e-06	62.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,1YHF1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	von willebrand factor, type A	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VCBS
GGS1_k127_4682860_0	1236689.MMALV_16330	9.594e-117	400.0	COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,3F2H0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3513	GARS_A,GARS_C,GARS_N
GGS1_k127_4682860_3	579137.Metvu_0163	2.644e-41	159.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,23QT7@183939|Methanococci	183939|Methanococci	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GGS1_k127_4682860_2	1094980.Mpsy_1082	2.637e-41	159.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,2N9PZ@224756|Methanomicrobia	224756|Methanomicrobia	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
GGS1_k127_4682860_1	690850.Desaf_0474	8.12e-53	200.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,437UD@68525|delta/epsilon subdivisions,2WYP2@28221|Deltaproteobacteria,2MCDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
GGS1_k127_4682860_4	1236689.MMALV_00200	1.303e-15	82.0	arCOG07412@1|root,arCOG07412@2157|Archaea,2Y0S5@28890|Euryarchaeota,3F2T8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4691592_0	555079.Toce_1201	2.155e-164	527.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GGS1_k127_4694629_0	1379698.RBG1_1C00001G0195	2.862e-80	273.0	COG1048@1|root,COG1048@2|Bacteria,2NNWW@2323|unclassified Bacteria	2|Bacteria	C	Aconitase C-terminal domain	dmdA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
GGS1_k127_4694629_2	1267535.KB906767_gene2002	2.304e-55	207.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
GGS1_k127_4694629_5	118161.KB235922_gene2359	0.0008891	50.0	COG3324@1|root,COG3324@2|Bacteria,1G82I@1117|Cyanobacteria	1117|Cyanobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GGS1_k127_4694629_1	1396418.BATQ01000016_gene4273	1.079e-74	262.0	COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia,2IVMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GGS1_k127_4694629_4	290397.Adeh_1433	3.201e-13	75.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
GGS1_k127_4694629_3	1120960.ATXG01000009_gene79	2.476e-14	85.0	COG2234@1|root,COG2234@2|Bacteria,2HFF1@201174|Actinobacteria,4FK8Z@85023|Microbacteriaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GGS1_k127_4703119_2	1265507.KB899639_gene794	6.627e-07	60.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1R6EB@1224|Proteobacteria	1224|Proteobacteria	S	Carbohydrate binding domain (family 25)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_20,CBM_25,PKD,fn3
GGS1_k127_4703119_3	1500301.JQMF01000021_gene5163	3.39e-05	57.0	COG3449@1|root,COG3449@2|Bacteria,1QTW6@1224|Proteobacteria,2TXEH@28211|Alphaproteobacteria,4BP2F@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	GyrI-like small molecule binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
GGS1_k127_4703119_0	368408.Tpen_0138	9.36e-80	280.0	COG1801@1|root,arCOG04291@2157|Archaea	2157|Archaea	L	DUF72 domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GGS1_k127_4703119_1	555079.Toce_1265	1.01e-10	66.0	COG3360@1|root,COG3360@2|Bacteria,1VF2X@1239|Firmicutes,24QS4@186801|Clostridia,42H2B@68295|Thermoanaerobacterales	186801|Clostridia	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GGS1_k127_4703119_4	460265.Mnod_2364	0.0001086	45.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,1JWH1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GGS1_k127_470862_0	797299.HALLA_16795	2.907e-33	136.0	COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,23RZ0@183963|Halobacteria	183963|Halobacteria	L	Uracil-DNA glycosylase	udg1	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GGS1_k127_4734239_1	1150474.JQJI01000017_gene593	2.816e-10	67.0	COG1661@1|root,COG1661@2|Bacteria,2GDE0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
GGS1_k127_4734239_0	1121091.AUMP01000005_gene1611	1.245e-134	437.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_4734819_4	529818.AMSG_00600T0	4.753e-09	68.0	KOG1218@1|root,KOG1225@1|root,KOG3594@1|root,KOG3597@1|root,KOG1218@2759|Eukaryota,KOG1225@2759|Eukaryota,KOG3597@2759|Eukaryota,KOG4289@2759|Eukaryota	2759|Eukaryota	O	homophilic cell adhesion via plasma membrane adhesion molecules	CSPG4	GO:0000187,GO:0000323,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0005912,GO:0005924,GO:0005927,GO:0006022,GO:0006023,GO:0006024,GO:0006026,GO:0006027,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007186,GO:0007275,GO:0007399,GO:0007517,GO:0008150,GO:0008152,GO:0008283,GO:0008347,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009653,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010721,GO:0010927,GO:0010975,GO:0010977,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016053,GO:0016203,GO:0016322,GO:0016477,GO:0017144,GO:0019220,GO:0019222,GO:0019538,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030054,GO:0030055,GO:0030154,GO:0030166,GO:0030182,GO:0030203,GO:0030204,GO:0030205,GO:0030206,GO:0030207,GO:0030208,GO:0030239,GO:0031032,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031346,GO:0031399,GO:0031401,GO:0031674,GO:0031974,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032787,GO:0032989,GO:0033674,GO:0034645,GO:0035556,GO:0040011,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042551,GO:0042692,GO:0042995,GO:0043034,GO:0043085,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043436,GO:0043549,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044272,GO:0044273,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045859,GO:0045860,GO:0045937,GO:0046394,GO:0048468,GO:0048469,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050650,GO:0050651,GO:0050654,GO:0050655,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051286,GO:0051338,GO:0051347,GO:0051489,GO:0051491,GO:0051674,GO:0051716,GO:0051960,GO:0051961,GO:0055001,GO:0055002,GO:0060255,GO:0060284,GO:0060491,GO:0060538,GO:0061061,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070925,GO:0071695,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072330,GO:0080090,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0120032,GO:0120034,GO:0120035,GO:1901135,GO:1901136,GO:1901137,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902531,GO:1902533,GO:1903510,GO:2000026	-	ko:K02599,ko:K08115,ko:K16507,ko:K16669,ko:K19013	ko01522,ko04320,ko04330,ko04391,ko04392,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04391,map04392,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002,ko00535,ko00536,ko04516	-	-	-	Cadherin_3,EB,Laminin_G_2
GGS1_k127_4734819_3	768679.TTX_0354	1.46e-30	128.0	COG1056@1|root,arCOG00972@2157|Archaea,2XQI1@28889|Crenarchaeota	28889|Crenarchaeota	F	nicotinamide-nucleotide adenylyltransferase	nadM	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
GGS1_k127_4734819_0	673860.AciM339_1547	1.42e-238	756.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
GGS1_k127_4734819_2	679926.Mpet_0058	7.652e-62	220.0	COG2013@1|root,arCOG01907@2157|Archaea,2XW0I@28890|Euryarchaeota,2N9P0@224756|Methanomicrobia	224756|Methanomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
GGS1_k127_4734819_1	673860.AciM339_0842	9.674e-66	234.0	COG0462@1|root,arCOG00067@2157|Archaea,2XTA8@28890|Euryarchaeota,3F2FN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
GGS1_k127_4735750_0	1236689.MMALV_09230	6.442e-220	716.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,3F2EY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
GGS1_k127_4735750_1	1120951.AUBG01000012_gene1660	2.044e-35	146.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
GGS1_k127_4735750_2	1236689.MMALV_16840	3.092e-08	56.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
GGS1_k127_4781143_4	192952.MM_2114	1.06e-05	57.0	arCOG06532@1|root,arCOG06532@2157|Archaea,2Y12Z@28890|Euryarchaeota,2NA6P@224756|Methanomicrobia	224756|Methanomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
GGS1_k127_4781143_1	436308.Nmar_1680	3.061e-28	126.0	COG0697@1|root,arCOG00273@2157|Archaea,41T37@651137|Thaumarchaeota	651137|Thaumarchaeota	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GGS1_k127_4781143_0	313596.RB2501_07210	4.44e-30	130.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
GGS1_k127_4781143_3	521674.Plim_0348	2.396e-16	85.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_4781143_2	1278073.MYSTI_06188	1.879e-18	93.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
GGS1_k127_4785511_2	453591.Igni_0451	2.3e-24	106.0	COG2058@1|root,arCOG04287@2157|Archaea,2XQSC@28889|Crenarchaeota	28889|Crenarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
GGS1_k127_4785511_1	673860.AciM339_0147	1.121e-77	272.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,3F2JW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s,Ribosomal_L10
GGS1_k127_4785511_0	439481.Aboo_0862	5.129e-78	266.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,3F2IX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GGS1_k127_4785511_3	647113.Metok_0540	7.233e-11	63.0	COG0080@1|root,arCOG04372@2157|Archaea,2XTJN@28890|Euryarchaeota,23QV5@183939|Methanococci	183939|Methanococci	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GGS1_k127_4790264_2	1324957.K933_07077	5.031e-11	76.0	COG1502@1|root,arCOG02039@2157|Archaea,2XTH3@28890|Euryarchaeota,23TAG@183963|Halobacteria	183963|Halobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pld	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GGS1_k127_4790264_1	342949.PNA2_1871	5.618e-87	316.0	COG0312@1|root,arCOG00322@2157|Archaea,2XVT5@28890|Euryarchaeota,2435V@183968|Thermococci	183968|Thermococci	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GGS1_k127_4790264_0	673860.AciM339_1333	6.87e-111	366.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,3F33F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GGS1_k127_4794219_1	391612.CY0110_15537	7.992e-81	308.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G1I0@1117|Cyanobacteria,3KK8R@43988|Cyanothece	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Lectin_C
GGS1_k127_4794219_3	304371.MCP_0042	1.493e-51	198.0	COG0438@1|root,arCOG01403@2157|Archaea,2XUDX@28890|Euryarchaeota	28890|Euryarchaeota	M	COG0438 Glycosyltransferase	gth1	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_4794219_4	1510531.JQJJ01000012_gene1655	1.102e-50	189.0	COG1024@1|root,COG1024@2|Bacteria,1NQM5@1224|Proteobacteria,2TSP1@28211|Alphaproteobacteria,3JUF6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_16935	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GGS1_k127_4794219_2	448385.sce7182	1.096e-56	204.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,42W6K@68525|delta/epsilon subdivisions,2WS34@28221|Deltaproteobacteria,2YZXI@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GGS1_k127_4794219_0	941824.TCEL_01001	2.279e-98	329.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,36DG5@31979|Clostridiaceae	186801|Clostridia	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GGS1_k127_4794219_6	646529.Desaci_3613	5.859e-07	51.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GGS1_k127_4819188_0	1344012.ATMI01000002_gene1423	0.0005229	53.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,4BV0H@82986|Tatumella	1236|Gammaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GGS1_k127_4829894_2	272844.PAB1245	7.209e-103	350.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,243PB@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GGS1_k127_4829894_14	673860.AciM339_1240	3.017e-06	58.0	COG4743@1|root,arCOG02884@2157|Archaea,2Y72F@28890|Euryarchaeota,3F39B@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
GGS1_k127_4829894_10	439481.Aboo_1284	2.96e-34	134.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,3F2T0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Peptidyl-tRNA hydrolase PTH2	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
GGS1_k127_4829894_13	529709.PYCH_17320	1.447e-25	121.0	COG1628@1|root,arCOG00928@2157|Archaea,2XXBV@28890|Euryarchaeota,242MJ@183968|Thermococci	183968|Thermococci	L	Belongs to the UPF0215 family	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
GGS1_k127_4829894_6	697281.Mahau_1836	6.757e-58	215.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
GGS1_k127_4829894_0	868131.MSWAN_0553	2.817e-123	409.0	COG1209@1|root,arCOG00667@2157|Archaea,2Y87B@28890|Euryarchaeota,23PGW@183925|Methanobacteria	183925|Methanobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GGS1_k127_4829894_9	565033.GACE_1120	3.58e-43	173.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,245XF@183980|Archaeoglobi	183980|Archaeoglobi	M	TIGRFAM dTDP-4-dehydrorhamnose reductase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GGS1_k127_4829894_5	868595.Desca_0881	7.574e-59	213.0	COG1898@1|root,COG1898@2|Bacteria,1V4G5@1239|Firmicutes,24IZ8@186801|Clostridia	186801|Clostridia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GGS1_k127_4829894_1	771875.Ferpe_0118	2.971e-115	381.0	COG1088@1|root,COG1088@2|Bacteria,2GCH1@200918|Thermotogae	200918|Thermotogae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GGS1_k127_4829894_8	304371.MCP_2719	2.272e-45	182.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,2N98D@224756|Methanomicrobia	224756|Methanomicrobia	M	Polysaccharide biosynthesis protein	rfbD-1	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GGS1_k127_4829894_3	1144275.COCOR_03547	7.558e-77	273.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
GGS1_k127_4829894_4	926550.CLDAP_39180	4.248e-60	220.0	COG1446@1|root,COG1446@2|Bacteria,2G6AS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
GGS1_k127_4829894_7	351160.RCIX205	1.149e-46	180.0	COG0451@1|root,arCOG01372@2157|Archaea,2Y3R7@28890|Euryarchaeota,2NAUM@224756|Methanomicrobia	224756|Methanomicrobia	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GGS1_k127_4829894_11	661478.OP10G_3417	3.022e-32	147.0	COG0457@1|root,COG0457@2|Bacteria	661478.OP10G_3417|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4829894_12	443906.CMM_0825	3.072e-29	137.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
GGS1_k127_4830154_1	374847.Kcr_0727	1.181e-10	75.0	COG3291@1|root,arCOG02508@2157|Archaea	2157|Archaea	G	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Malectin,PKD
GGS1_k127_4830154_0	517417.Cpar_1684	6.84e-97	336.0	COG1741@1|root,COG1741@2|Bacteria,1FEUN@1090|Chlorobi	1090|Chlorobi	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GGS1_k127_4830154_2	937777.Deipe_2473	0.0005125	49.0	COG2132@1|root,COG3794@1|root,COG2132@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
GGS1_k127_4834459_0	1035308.AQYY01000002_gene199	9.273e-36	148.0	2ANM6@1|root,31DKG@2|Bacteria,1TUK2@1239|Firmicutes,25I50@186801|Clostridia,2668F@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4839859_4	673860.AciM339_0290	4.187e-19	88.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
GGS1_k127_4839859_7	1210884.HG799464_gene11056	1.43e-08	64.0	COG1371@1|root,COG1371@2|Bacteria,2J0RY@203682|Planctomycetes	203682|Planctomycetes	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
GGS1_k127_4839859_0	289376.THEYE_A1750	2.012e-156	508.0	COG1690@1|root,COG1690@2|Bacteria,3J0X0@40117|Nitrospirae	40117|Nitrospirae	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GGS1_k127_4839859_3	439481.Aboo_1414	2.827e-33	131.0	COG1888@1|root,arCOG04140@2157|Archaea,2Y02A@28890|Euryarchaeota,3F3DR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterized ArCR, COG1888	-	-	-	ko:K09732	-	-	-	-	ko00000	-	-	-	DUF211
GGS1_k127_4839859_6	410358.Mlab_1514	1.072e-10	67.0	COG1400@1|root,arCOG01217@2157|Archaea,2Y68X@28890|Euryarchaeota,2NA5V@224756|Methanomicrobia	224756|Methanomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	srp19	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
GGS1_k127_4839859_2	673860.AciM339_1543	1.005e-36	147.0	COG2007@1|root,arCOG04154@2157|Archaea,2XYXX@28890|Euryarchaeota,3F2SE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal protein S8e	rps8e	GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
GGS1_k127_4839859_1	1054217.TALC_00160	1.426e-152	492.0	COG1222@1|root,arCOG01306@2157|Archaea	2157|Archaea	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates	pan	GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	-	ko:K03420	ko03050,map03050	M00343	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
GGS1_k127_4839859_5	402880.MmarC5_1762	8.793e-14	81.0	COG1813@1|root,arCOG01863@2157|Archaea,2XXND@28890|Euryarchaeota,23QX1@183939|Methanococci	183939|Methanococci	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
GGS1_k127_485295_0	751944.HALDL1_00070	1.745e-05	55.0	COG4914@1|root,arCOG04119@2157|Archaea,2Y8H3@28890|Euryarchaeota,241AZ@183963|Halobacteria	183963|Halobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GGS1_k127_4855632_2	1278073.MYSTI_07208	1.514e-56	200.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GGS1_k127_4855632_0	1236689.MMALV_01790	5.227e-75	271.0	COG0592@1|root,arCOG00488@2157|Archaea,2XT8B@28890|Euryarchaeota,3F2MA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
GGS1_k127_4855632_1	1236689.MMALV_00630	7.2e-71	265.0	COG2219@1|root,arCOG03013@2157|Archaea,2XTDT@28890|Euryarchaeota,3F2P0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
GGS1_k127_4855632_3	351160.LRC299	1.494e-37	153.0	COG1467@1|root,arCOG04110@2157|Archaea,2XUZF@28890|Euryarchaeota,2N95F@224756|Methanomicrobia	224756|Methanomicrobia	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
GGS1_k127_4857553_3	1523503.JPMY01000010_gene2552	5.05e-79	279.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1GS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0475 Kef-type K transport systems, membrane components	IV02_22945	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
GGS1_k127_4857553_5	926560.KE387023_gene3863	5.882e-10	72.0	COG1331@1|root,COG1331@2|Bacteria,1WI7F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GGS1_k127_4857553_4	985054.JQEZ01000001_gene2007	1.553e-11	70.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2UF3C@28211|Alphaproteobacteria,4NCSP@97050|Ruegeria	28211|Alphaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	tusA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
GGS1_k127_4857553_0	237368.SCABRO_01193	1.444e-132	447.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GGS1_k127_4857553_1	326427.Cagg_2109	2.148e-93	322.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GGS1_k127_4857553_2	439481.Aboo_0781	8.132e-83	284.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
GGS1_k127_488320_1	460265.Mnod_2364	5.309e-11	71.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,1JWH1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GGS1_k127_488320_0	1123228.AUIH01000092_gene552	2.653e-58	228.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4893430_0	1333523.L593_07070	7.112e-31	133.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XVHG@28890|Euryarchaeota,23SZN@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
GGS1_k127_4893430_1	1487923.DP73_04955	4.013e-30	131.0	COG0467@1|root,COG0467@2|Bacteria,1TSIM@1239|Firmicutes,24DRY@186801|Clostridia,260SN@186807|Peptococcaceae	186801|Clostridia	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GGS1_k127_4893430_2	1183377.Py04_0138	1.291e-09	64.0	COG2339@1|root,arCOG02985@2157|Archaea,2XSXV@28890|Euryarchaeota,242IQ@183968|Thermococci	183968|Thermococci	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GGS1_k127_4915125_3	1227453.C444_09500	7.644e-19	92.0	COG0640@1|root,arCOG00731@2157|Archaea,2XYSK@28890|Euryarchaeota,23WPS@183963|Halobacteria	183963|Halobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GGS1_k127_4915125_0	671143.DAMO_0386	4.991e-281	877.0	COG1048@1|root,COG1048@2|Bacteria,2NNWW@2323|unclassified Bacteria	2|Bacteria	C	Aconitase C-terminal domain	dmdA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
GGS1_k127_4915125_2	1459636.NTE_00903	6.089e-24	109.0	arCOG10856@1|root,arCOG10856@2157|Archaea	1459636.NTE_00903|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4915125_4	439481.Aboo_0564	3.095e-17	84.0	COG1998@1|root,arCOG04183@2157|Archaea,2XZZ0@28890|Euryarchaeota,3F2VM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
GGS1_k127_4915125_6	1041930.Mtc_0178	5.531e-12	71.0	COG2004@1|root,arCOG04182@2157|Archaea,2XXXB@28890|Euryarchaeota,2NA0E@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
GGS1_k127_4915125_1	439481.Aboo_0566	2.425e-24	109.0	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,3F2T2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
GGS1_k127_4915125_5	1236689.MMALV_04380	2.142e-16	79.0	COG2093@1|root,arCOG04077@2157|Archaea,2Y6YF@28890|Euryarchaeota,3F2W7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
GGS1_k127_4916802_0	1078085.HMPREF1210_01398	4.221e-23	117.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,1V9TE@1239|Firmicutes,4HPS1@91061|Bacilli	91061|Bacilli	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GGS1_k127_4916802_1	416348.Hlac_2824	9.353e-20	106.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GGS1_k127_4921621_0	926550.CLDAP_02100	3.105e-05	57.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2,PMT_4TMC
GGS1_k127_492945_2	1405498.SSIM_03705	4.075e-36	154.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,4GYDD@90964|Staphylococcaceae	91061|Bacilli	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GGS1_k127_492945_1	673860.AciM339_0867	8.228e-56	205.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,3F2JY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_1,KH_6,S1
GGS1_k127_492945_0	673860.AciM339_0868	3.31e-88	301.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,3F2GE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
GGS1_k127_4945645_3	273116.14324566	5.443e-14	84.0	COG0200@1|root,arCOG00779@2157|Archaea,2Y6A4@28890|Euryarchaeota,241UA@183967|Thermoplasmata	183967|Thermoplasmata	J	Binds to the 23S rRNA	rpl15	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GGS1_k127_4945645_1	868131.MSWAN_1449	5.524e-39	160.0	COG1841@1|root,arCOG04086@2157|Archaea,2XWGP@28890|Euryarchaeota,23P1Y@183925|Methanobacteria	183925|Methanobacteria	J	ribosomal protein	rpl30	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
GGS1_k127_4945645_0	1236689.MMALV_14060	6.947e-82	281.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,3F2HF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S12 plays an important role in translational accuracy	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GGS1_k127_4945645_2	673860.AciM339_1117	9.24e-25	106.0	COG0256@1|root,arCOG04088@2157|Archaea,2XTWT@28890|Euryarchaeota,3F2QM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
GGS1_k127_4945968_0	1048834.TC41_2178	2.317e-104	350.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2784A@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GGS1_k127_4945968_3	693661.Arcve_1632	2.281e-05	51.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GGS1_k127_4945968_2	415426.Hbut_1353	4.063e-13	70.0	COG2888@1|root,arCOG01989@2157|Archaea,2XRFA@28889|Crenarchaeota	28889|Crenarchaeota	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
GGS1_k127_4945968_1	439481.Aboo_0892	3.452e-14	75.0	COG2092@1|root,arCOG01988@2157|Archaea,2Y75E@28890|Euryarchaeota,3F3FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
GGS1_k127_4951128_1	292415.Tbd_2203	1.55e-12	69.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,1KSQN@119069|Hydrogenophilales	119069|Hydrogenophilales	O	4Fe-4S single cluster domain	-	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
GGS1_k127_4951128_0	693661.Arcve_1550	4.587e-22	105.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GGS1_k127_4985356_0	439481.Aboo_0018	0.0001504	55.0	COG0457@1|root,arCOG02527@1|root,arCOG07561@1|root,arCOG02527@2157|Archaea,arCOG03032@2157|Archaea,arCOG07561@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8,VWA
GGS1_k127_4987815_4	1173263.Syn7502_01261	3.423e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_14,TPR_16,TPR_2,TPR_6,TPR_8
GGS1_k127_4987815_5	435590.BVU_2965	3.662e-06	56.0	COG1708@1|root,COG1708@2|Bacteria,4NVKN@976|Bacteroidetes,2G0JJ@200643|Bacteroidia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GGS1_k127_4987815_1	246969.TAM4_1580	4.622e-13	75.0	COG1895@1|root,arCOG02123@2157|Archaea,2Y6DM@28890|Euryarchaeota,244MT@183968|Thermococci	183968|Thermococci	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
GGS1_k127_4987815_2	927658.AJUM01000042_gene1454	7.138e-12	77.0	COG3209@1|root,COG4290@1|root,COG3209@2|Bacteria,COG4290@2|Bacteria,4NGJF@976|Bacteroidetes,2FQPQ@200643|Bacteroidia,3XKYR@558415|Marinilabiliaceae	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Ribonuclease,SpvB,TcdB_toxin_midN,VCBS
GGS1_k127_4987815_6	1112214.AHIS01000051_gene2462	7.16e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,1PVFG@1224|Proteobacteria,2V3G8@28211|Alphaproteobacteria,2K1VW@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4987815_3	304371.MCP_1137	7.511e-12	76.0	COG4083@1|root,arCOG04471@2157|Archaea,2XTQZ@28890|Euryarchaeota,2N9VN@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
GGS1_k127_4987815_0	304371.MCP_2060	6.355e-37	153.0	arCOG12322@1|root,arCOG12322@2157|Archaea,2Y5I1@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_4995670_3	1210908.HSB1_31490	0.0003798	44.0	COG0198@1|root,arCOG04094@2157|Archaea,2XXV4@28890|Euryarchaeota,23W80@183963|Halobacteria	183963|Halobacteria	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24p	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
GGS1_k127_4995670_0	673860.AciM339_1110	1.606e-57	208.0	COG1471@1|root,arCOG04093@2157|Archaea,2XT03@28890|Euryarchaeota,3F2KF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal family S4e	rps4e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
GGS1_k127_4995670_1	1236689.MMALV_14130	3.611e-55	198.0	COG0094@1|root,arCOG04092@2157|Archaea,2XTRN@28890|Euryarchaeota,3F2KJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
GGS1_k127_4995670_2	1236689.MMALV_14120	1.123e-08	64.0	COG0199@1|root,arCOG00782@2157|Archaea,2Y68V@28890|Euryarchaeota,3F2V3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
GGS1_k127_4999764_3	70601.3257742	9.938e-10	63.0	COG2245@1|root,arCOG01644@2157|Archaea,2XY66@28890|Euryarchaeota,24464@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF996
GGS1_k127_4999764_0	1123274.KB899437_gene680	2.605e-29	126.0	COG1652@1|root,COG1652@2|Bacteria,2J6VQ@203691|Spirochaetes	203691|Spirochaetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GGS1_k127_4999764_1	1458357.BG58_14265	2.038e-10	70.0	COG2135@1|root,COG2135@2|Bacteria,1N9TF@1224|Proteobacteria,2VVGW@28216|Betaproteobacteria,1K0YV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GGS1_k127_4999764_5	1232437.KL661986_gene3679	0.0008502	49.0	COG3829@1|root,COG3852@1|root,COG4564@1|root,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4564@2|Bacteria,1QW3X@1224|Proteobacteria,42YCI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PAS fold	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
GGS1_k127_4999764_2	228410.NE1241	2.742e-10	72.0	COG2304@1|root,COG2304@2|Bacteria,1R88T@1224|Proteobacteria,2VVPK@28216|Betaproteobacteria,371UW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPC,Tyrosinase
GGS1_k127_5019246_1	585501.HMPREF6123_1456	1.006e-34	143.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,2PQYT@265975|Oribacterium	186801|Clostridia	S	cog cog1672	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
GGS1_k127_5019246_0	1459636.NTE_03216	1.283e-232	744.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GGS1_k127_5019246_2	234267.Acid_3586	2.9e-29	131.0	COG1404@1|root,COG1404@2|Bacteria,3Y2EZ@57723|Acidobacteria	57723|Acidobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GGS1_k127_5025257_0	439481.Aboo_0013	1.599e-24	116.0	COG1305@1|root,arCOG02165@2157|Archaea,2Y71W@28890|Euryarchaeota,3F376@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GGS1_k127_5027351_0	673860.AciM339_1197	3.124e-137	452.0	COG0433@1|root,arCOG00280@2157|Archaea,2Y7MA@28890|Euryarchaeota,3F30Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
GGS1_k127_5027351_3	1236689.MMALV_01400	8.868e-26	121.0	COG1849@1|root,arCOG01224@2157|Archaea,2XYS0@28890|Euryarchaeota,3F2SZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
GGS1_k127_5027351_5	273075.Ta1159	1.546e-22	103.0	COG1860@1|root,arCOG04477@2157|Archaea,2XX8X@28890|Euryarchaeota,241W0@183967|Thermoplasmata	183967|Thermoplasmata	S	Uncharacterised protein family (UPF0179)	-	-	-	ko:K09730	-	-	-	-	ko00000	-	-	-	UPF0179
GGS1_k127_5027351_2	673860.AciM339_0510	3.012e-110	377.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,3F2IT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
GGS1_k127_5027351_7	634498.mru_0483	3.572e-07	63.0	COG0250@1|root,arCOG01920@2157|Archaea,2XWGQ@28890|Euryarchaeota,23P3U@183925|Methanobacteria	183925|Methanobacteria	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
GGS1_k127_5027351_6	269797.Mbar_A0290	5.056e-22	111.0	COG1967@1|root,arCOG02177@2157|Archaea,2XT8V@28890|Euryarchaeota,2N9NX@224756|Methanomicrobia	224756|Methanomicrobia	S	Membrane protein of unknown function DUF63	-	-	-	-	-	-	-	-	-	-	-	-	DUF63
GGS1_k127_5027351_4	929712.KI912613_gene1825	1.756e-23	109.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GGS1_k127_5027351_1	1121335.Clst_1943	2.442e-127	415.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GGS1_k127_5038179_1	247639.MGP2080_00305	1.965e-39	160.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1J53H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
GGS1_k127_5038179_0	404589.Anae109_3919	6.659e-72	250.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2Z04D@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
GGS1_k127_5038179_2	797302.Halru_1577	1.668e-32	135.0	COG0688@1|root,arCOG04470@2157|Archaea,2XX5J@28890|Euryarchaeota,23TM1@183963|Halobacteria	183963|Halobacteria	I	phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GGS1_k127_5050713_3	304371.MCP_1218	0.0001569	48.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,2N96G@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GGS1_k127_5050713_0	673860.AciM339_1402	0.0	1496.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,3F2FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GGS1_k127_5050713_2	579137.Metvu_1537	2.965e-13	77.0	COG2012@1|root,arCOG04258@2157|Archaea,2Y0EY@28890|Euryarchaeota,23RAF@183939|Methanococci	183939|Methanococci	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
GGS1_k127_5050713_1	751944.HALDL1_12585	1.486e-31	134.0	COG0402@1|root,arCOG00692@2157|Archaea,2XSYB@28890|Euryarchaeota,23SA9@183963|Halobacteria	183963|Halobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD3	-	3.5.4.1,3.5.4.3	ko:K01485,ko:K01487	ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100	-	R00974,R01411,R01676,R02922	RC00074,RC00204,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GGS1_k127_5062541_0	203119.Cthe_0436	9.122e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes	1239|Firmicutes	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
GGS1_k127_5071043_1	1125863.JAFN01000001_gene880	3.146e-43	171.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GGS1_k127_5071043_0	1123024.AUII01000053_gene167	1.323e-133	439.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
GGS1_k127_5071043_3	1094980.Mpsy_1303	1.709e-33	133.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2N9YG@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GGS1_k127_5071043_4	525146.Ddes_1199	1.312e-12	75.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MC2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GGS1_k127_5071043_2	1128421.JAGA01000003_gene2766	5.966e-42	177.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
GGS1_k127_5086917_0	1123228.AUIH01000038_gene2740	0.0001963	54.0	COG1361@1|root,COG3291@1|root,COG3656@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG3656@2|Bacteria,1MWIT@1224|Proteobacteria,1S1VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,PKD
GGS1_k127_509192_7	693661.Arcve_1936	4.019e-12	78.0	COG0289@1|root,arCOG04393@2157|Archaea,2XTJU@28890|Euryarchaeota,24638@183980|Archaeoglobi	183980|Archaeoglobi	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GGS1_k127_509192_0	204669.Acid345_2493	1.089e-84	290.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria,2JICI@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GGS1_k127_509192_5	1121945.ATXS01000002_gene677	1.212e-26	120.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX5M@28890|Euryarchaeota,23VKV@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	trh3	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GGS1_k127_509192_2	485914.Hmuk_0398	4.086e-70	250.0	COG0451@1|root,arCOG03018@2157|Archaea,2XWB1@28890|Euryarchaeota,23TGM@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GGS1_k127_509192_3	926550.CLDAP_14520	1.309e-58	216.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95,1.17.1.9	ko:K00058,ko:K00122	ko00260,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00519,R01513	RC00031,RC02796	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GGS1_k127_509192_8	47716.JOFH01000019_gene4949	1.013e-06	56.0	COG2329@1|root,COG2329@2|Bacteria,2GN7N@201174|Actinobacteria	201174|Actinobacteria	S	SchA/CurD like domain	sppG	-	-	-	-	-	-	-	-	-	-	-	ABM,SchA_CurD
GGS1_k127_509192_9	243233.MCA3064	3.531e-06	54.0	2EQEC@1|root,33I0C@2|Bacteria,1NP5N@1224|Proteobacteria,1SGGK@1236|Gammaproteobacteria,1XGVA@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_509192_4	694429.Pyrfu_0913	6.909e-49	187.0	COG1355@1|root,arCOG01728@2157|Archaea,2XPQS@28889|Crenarchaeota	28889|Crenarchaeota	S	Belongs to the MEMO1 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GGS1_k127_509192_1	1054217.TALC_00169	2.955e-77	266.0	COG0052@1|root,arCOG04245@2157|Archaea,2XTHM@28890|Euryarchaeota,241MQ@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GGS1_k127_509192_6	673860.AciM339_0075	1.549e-13	73.0	COG1758@1|root,arCOG01268@2157|Archaea,2XZSW@28890|Euryarchaeota,3F2TZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	2.7.7.6	ko:K03055	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb6
GGS1_k127_5095645_1	1082933.MEA186_04294	2.42e-07	63.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,2U31G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GGS1_k127_5095645_0	99598.Cal7507_1772	2.8e-15	87.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GIZT@1117|Cyanobacteria,1HMI7@1161|Nostocales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
GGS1_k127_5138483_0	926556.Echvi_3331	1.77e-07	58.0	COG0484@1|root,COG0484@2|Bacteria,4NQGK@976|Bacteroidetes,47QV8@768503|Cytophagia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5138483_1	1120968.AUBX01000009_gene473	2.717e-05	56.0	COG0484@1|root,COG0484@2|Bacteria,4NQGK@976|Bacteroidetes,47QV8@768503|Cytophagia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5148820_0	504487.JCM19302_4247	5.897e-05	57.0	COG3209@1|root,COG3325@1|root,COG3209@2|Bacteria,COG3325@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
GGS1_k127_5166186_2	1236689.MMALV_15550	3.734e-08	60.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota	28890|Euryarchaeota	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
GGS1_k127_5166186_0	1236689.MMALV_15550	5.169e-44	171.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota	28890|Euryarchaeota	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
GGS1_k127_5166186_1	673860.AciM339_0003	9.378e-43	161.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota,3F2PU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
GGS1_k127_51698_1	1265505.ATUG01000001_gene4610	3.614e-13	77.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,42XEQ@68525|delta/epsilon subdivisions,2WTD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
GGS1_k127_51698_2	1245471.PCA10_07040	2.69e-09	67.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,1TCA7@1236|Gammaproteobacteria,1YK48@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5191436_2	1382358.JHVN01000010_gene1568	3.948e-05	52.0	COG2030@1|root,COG2030@2|Bacteria,1V7QY@1239|Firmicutes,4HJBV@91061|Bacilli	91061|Bacilli	I	Dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GGS1_k127_5191436_0	1121423.JONT01000001_gene2030	9.134e-75	263.0	COG0020@1|root,COG0020@2|Bacteria,1TRKB@1239|Firmicutes,248R2@186801|Clostridia,2612A@186807|Peptococcaceae	186801|Clostridia	I	PFAM Di-trans-poly-cis-decaprenylcistransferase	uppS1	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GGS1_k127_5191436_1	1444310.JANV01000138_gene1990	6.782e-11	76.0	COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,1ZRBP@1386|Bacillus	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GGS1_k127_5195502_0	1094980.Mpsy_0851	2.967e-145	477.0	COG0550@1|root,arCOG01527@2157|Archaea,arCOG06233@2157|Archaea,2XU6T@28890|Euryarchaeota,2N96B@224756|Methanomicrobia	224756|Methanomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	HHH_5,Topoisom_bac,Toprim,zf-C4_Topoisom
GGS1_k127_5203482_2	673860.AciM339_1106	2.422e-10	65.0	COG1588@1|root,arCOG00784@2157|Archaea,2Y6YD@28890|Euryarchaeota,3F2VY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
GGS1_k127_5203482_1	1054217.TALC_01327	7.484e-21	94.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,241TJ@183967|Thermoplasmata	183967|Thermoplasmata	J	posttranscriptional regulation of gene expression	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GGS1_k127_5203482_3	456442.Mboo_1902	1.912e-07	55.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,2N9W4@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GGS1_k127_5203482_4	1041930.Mtc_1329	2.774e-06	52.0	COG0255@1|root,arCOG00785@2157|Archaea,2XZUQ@28890|Euryarchaeota,2NA4R@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
GGS1_k127_5203482_0	1236689.MMALV_14200	1.353e-75	265.0	COG0092@1|root,arCOG04097@2157|Archaea,2XTHR@28890|Euryarchaeota,3F2JC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S3	rps3	GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
GGS1_k127_5207906_0	1236689.MMALV_04600	1.039e-74	261.0	COG1679@1|root,arCOG04278@2157|Archaea,2XTY6@28890|Euryarchaeota,3F2GP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
GGS1_k127_5207906_1	604354.TSIB_1943	2.675e-42	166.0	COG1786@1|root,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota,2445F@183968|Thermococci	183968|Thermococci	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
GGS1_k127_5207906_2	1122239.AULS01000016_gene606	3.618e-10	68.0	COG0005@1|root,COG0005@2|Bacteria,2GKGG@201174|Actinobacteria,4FMGC@85023|Microbacteriaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GGS1_k127_5221534_0	555079.Toce_1201	8.577e-162	519.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GGS1_k127_5226509_8	1040989.AWZU01000011_gene4022	0.0002964	44.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,3JWCZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GGS1_k127_5226509_2	287986.DV20_09415	2.679e-37	157.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4E10F@85010|Pseudonocardiales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GGS1_k127_5226509_1	1121430.JMLG01000032_gene1670	5.995e-58	211.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,260CU@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM TIGR00268 family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
GGS1_k127_5226509_6	272134.KB731324_gene5029	9.553e-17	91.0	COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1HARR@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
GGS1_k127_5226509_4	1449357.JQLK01000001_gene870	2.129e-25	117.0	COG1011@1|root,COG1011@2|Bacteria,1WIPE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GGS1_k127_5226509_7	1437425.CSEC_0477	1.734e-05	59.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,Calx-beta,DUF11,DUF2341,Invasin_D3,Laminin_G_3,SdrD_B,VCBS
GGS1_k127_5226509_0	673860.AciM339_0717	9.473e-82	285.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,3F2FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
GGS1_k127_5226509_5	1410620.SHLA_86c000040	2.414e-18	93.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,4B8DE@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
GGS1_k127_5226509_3	859657.RPSI07_0559	1.475e-26	115.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1K08P@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GGS1_k127_5229521_4	521098.Aaci_0827	8.147e-90	307.0	COG0508@1|root,COG0508@2|Bacteria,1U936@1239|Firmicutes,4HAUD@91061|Bacilli	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC2	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GGS1_k127_5229521_0	404589.Anae109_1994	1.746e-145	467.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GGS1_k127_5229521_3	867903.ThesuDRAFT_01196	2.663e-93	318.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia	186801|Clostridia	C	dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GGS1_k127_5229521_1	1192034.CAP_2176	2.464e-106	356.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GGS1_k127_5229521_2	262724.TT_C1747	8.73e-104	348.0	COG0320@1|root,COG0320@2|Bacteria,1WIE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GGS1_k127_5229521_5	1191523.MROS_1971	3.444e-61	216.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GGS1_k127_5229521_6	1134474.O59_003282	2.909e-18	99.0	COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5238787_1	398578.Daci_4515	2.093e-08	69.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
GGS1_k127_5238787_0	443144.GM21_3561	6.187e-23	117.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,CarboxypepD_reg,DUF11,DUF3494,SdrD_B
GGS1_k127_5240204_0	1379698.RBG1_1C00001G1376	1.52e-49	183.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
GGS1_k127_5240204_1	161156.JQKW01000001_gene1436	1.936e-13	76.0	COG0517@1|root,COG0517@2|Bacteria,2GHXB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GGS1_k127_5241825_0	797114.C475_20702	1.16e-10	75.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWHT@28890|Euryarchaeota,23V64@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	gntR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5,MarR_2
GGS1_k127_5241825_1	1267535.KB906767_gene2554	4.47e-08	63.0	COG0467@1|root,COG0467@2|Bacteria,3Y6QG@57723|Acidobacteria,2JM7Y@204432|Acidobacteriia	204432|Acidobacteriia	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GGS1_k127_5261402_1	926560.KE387025_gene4132	1.255e-26	112.0	COG2085@1|root,COG2085@2|Bacteria,1WMWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	F420_oxidored
GGS1_k127_5261402_2	298654.FraEuI1c_6886	1.347e-25	120.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GGS1_k127_5261402_0	3055.EDP07936	5.961e-73	252.0	COG0225@1|root,KOG1635@2759|Eukaryota,380HK@33090|Viridiplantae,34MJ2@3041|Chlorophyta	3041|Chlorophyta	O	methionine sulfoxide reductase	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GGS1_k127_5263316_0	479434.Sthe_1107	5.769e-177	563.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,27Z10@189775|Thermomicrobia	189775|Thermomicrobia	E	Urocanase C-terminal domain	-	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GGS1_k127_5290873_0	253839.SSNG_06730	3.247e-10	72.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
GGS1_k127_529668_4	1172188.KB911820_gene2997	8.086e-40	158.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4FFYV@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GGS1_k127_529668_3	386456.JQKN01000008_gene1390	4.415e-59	222.0	COG0420@1|root,arCOG00397@2157|Archaea,2XWH1@28890|Euryarchaeota	28890|Euryarchaeota	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity	mre11	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GGS1_k127_529668_2	521011.Mpal_0018	2.29e-63	247.0	COG0419@1|root,arCOG00368@2157|Archaea,2XTC7@28890|Euryarchaeota	28890|Euryarchaeota	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex	rad50	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_21,AAA_23,Rad50_zn_hook,SMC_N
GGS1_k127_529668_1	224325.AF_0367	6.751e-78	276.0	COG0477@1|root,arCOG00147@2157|Archaea,2XTS8@28890|Euryarchaeota,246N5@183980|Archaeoglobi	183980|Archaeoglobi	G	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
GGS1_k127_529668_0	1125863.JAFN01000001_gene2044	2.339e-172	554.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
GGS1_k127_5302835_0	316067.Geob_1372	9.233e-10	71.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5313478_1	1324957.K933_10799	0.0009135	49.0	COG3398@1|root,arCOG02611@2157|Archaea,2XX30@28890|Euryarchaeota,23VMW@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
GGS1_k127_5313478_0	1380394.JADL01000020_gene1849	5.644e-62	233.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,2V6PW@28211|Alphaproteobacteria,2JR0Q@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1055 Na H antiporter NhaD and related arsenite permeases	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
GGS1_k127_5315985_0	485916.Dtox_1611	8.757e-77	264.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GGS1_k127_5315985_1	543632.JOJL01000004_gene4319	8.114e-40	156.0	COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria,4DEWX@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GGS1_k127_5315985_6	192952.MM_0546	9.641e-05	49.0	arCOG05149@1|root,arCOG05149@2157|Archaea,2Y4ZG@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5315985_3	1499967.BAYZ01000173_gene5813	6.552e-10	70.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
GGS1_k127_5315985_4	931277.C448_00522	7.846e-10	66.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWHT@28890|Euryarchaeota,23V64@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	gntR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5,MarR_2
GGS1_k127_5315985_5	485913.Krac_4148	4.721e-07	62.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_5315985_2	1122921.KB898210_gene2775	3.629e-11	72.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,26TS3@186822|Paenibacillaceae	91061|Bacilli	P	CopC domain	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,YtkA
GGS1_k127_5317736_0	1094980.Mpsy_2341	5.458e-163	529.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,2N92P@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GGS1_k127_5335669_1	342949.PNA2_1843	1.06e-37	146.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,242RN@183968|Thermococci	183968|Thermococci	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
GGS1_k127_5335669_0	768679.TTX_1861	9.936e-75	262.0	COG0130@1|root,arCOG00987@2157|Archaea,2XPWX@28889|Crenarchaeota	28889|Crenarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
GGS1_k127_5345346_2	574966.KB898653_gene1393	2.831e-40	171.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1XKKT@135619|Oceanospirillales	135619|Oceanospirillales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GGS1_k127_5345346_1	251221.35212829	6.242e-49	202.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	CBM9_1,CBM_6
GGS1_k127_5345346_0	234267.Acid_6881	1.526e-89	334.0	COG1361@1|root,COG3534@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3534@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,DUF4347,Glyco_hydro_43,He_PIG,P_proprotein,Peptidase_S8,TIG
GGS1_k127_5347453_1	1121272.KB903250_gene2799	5.456e-05	57.0	2EEXH@1|root,338QV@2|Bacteria,2ICQN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
GGS1_k127_5347453_0	43354.JOIJ01000013_gene692	1.266e-22	107.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
GGS1_k127_5367327_5	1349785.BAUG01000002_gene123	0.0008695	50.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
GGS1_k127_5367327_1	439481.Aboo_0123	1.089e-68	240.0	COG0638@1|root,arCOG00970@2157|Archaea,2XUIZ@28890|Euryarchaeota,3F2PC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
GGS1_k127_5367327_0	439481.Aboo_0122	1.094e-239	760.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,3F2GJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	KH domain	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
GGS1_k127_5367327_4	468556.AQYG01000047_gene1592	7.037e-33	139.0	COG3548@1|root,COG3548@2|Bacteria,2IQG2@201174|Actinobacteria,4GACC@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GGS1_k127_5367327_3	1459636.NTE_01122	7.789e-40	153.0	COG0783@1|root,arCOG01101@2157|Archaea	2157|Archaea	P	Belongs to the Dps family	frt	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
GGS1_k127_5367327_2	269797.Mbar_A2038	3.704e-45	175.0	COG1899@1|root,arCOG04142@2157|Archaea,2XUTF@28890|Euryarchaeota,2N9AF@224756|Methanomicrobia	224756|Methanomicrobia	O	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys-1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GGS1_k127_5368074_0	456442.Mboo_1019	5.42e-106	355.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GGS1_k127_5368074_1	456442.Mboo_0426	1.182e-65	241.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,2N9R3@224756|Methanomicrobia	224756|Methanomicrobia	V	TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GGS1_k127_5368074_2	273063.STK_07210	1.504e-35	149.0	COG1225@1|root,arCOG00310@2157|Archaea,2XRWS@28889|Crenarchaeota	28889|Crenarchaeota	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GGS1_k127_5368074_4	1227487.C474_04450	0.0009509	49.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,240UY@183963|Halobacteria	183963|Halobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_2,TPR_8
GGS1_k127_5368074_3	1089549.AZUQ01000001_gene1833	8.711e-09	67.0	COG3214@1|root,COG3214@2|Bacteria,2I62A@201174|Actinobacteria,4F01S@85014|Glycomycetales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GGS1_k127_5371842_2	8496.XP_006278391.1	1.419e-05	54.0	KOG4059@1|root,KOG4059@2759|Eukaryota,3A621@33154|Opisthokonta,3BSXB@33208|Metazoa,3CWA1@33213|Bilateria,47ZBD@7711|Chordata,498BY@7742|Vertebrata	33208|Metazoa	S	gamma-glutamylcyclotransferase activity	GGCT	GO:0001836,GO:0002376,GO:0003674,GO:0003824,GO:0003839,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008637,GO:0009058,GO:0009611,GO:0009987,GO:0012501,GO:0016043,GO:0016829,GO:0016840,GO:0016842,GO:0019184,GO:0023052,GO:0032501,GO:0034641,GO:0042060,GO:0042381,GO:0042398,GO:0042802,GO:0042803,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0045087,GO:0046983,GO:0050789,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097190,GO:1901564,GO:1901566,GO:1901576	4.3.2.9	ko:K00682	ko00480,map00480	-	R02743,R03749	RC00064,RC00777	ko00000,ko00001,ko01000	-	-	-	AIG2_2
GGS1_k127_5371842_0	673860.AciM339_0952	8.474e-42	161.0	COG1591@1|root,arCOG00919@2157|Archaea,2XY2Q@28890|Euryarchaeota,3F2NJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Archaeal holliday junction resolvase (hjc)	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
GGS1_k127_5371842_1	519442.Huta_0078	1.858e-38	149.0	COG1321@1|root,arCOG02100@2157|Archaea,2XX2E@28890|Euryarchaeota,23VND@183963|Halobacteria	183963|Halobacteria	K	COG1321 Mn-dependent transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
GGS1_k127_542617_0	926550.CLDAP_19950	7.758e-09	65.0	2E1CR@1|root,32WS9@2|Bacteria,2G8CY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_552120_0	748247.AZKH_2928	3.291e-262	820.0	COG1977@1|root,COG2414@1|root,COG1977@2|Bacteria,COG2414@2|Bacteria,1NQ92@1224|Proteobacteria,2W044@28216|Betaproteobacteria,2KY26@206389|Rhodocyclales	206389|Rhodocyclales	CH	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AFOR_C,AFOR_N,ThiS
GGS1_k127_552120_2	309800.C498_16124	2.35e-10	69.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XWJ8@28890|Euryarchaeota,23VFA@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_10
GGS1_k127_552120_1	1236689.MMALV_00330	1.535e-48	176.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,3F2FH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
GGS1_k127_553299_1	368407.Memar_1039	4.047e-30	125.0	COG1392@1|root,arCOG02640@2157|Archaea	2157|Archaea	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GGS1_k127_553299_0	240015.ACP_1356	1.881e-37	160.0	COG4409@1|root,COG4409@2|Bacteria,3Y8VS@57723|Acidobacteria	57723|Acidobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_553299_2	351160.RCIX702	1.328e-20	93.0	COG0468@1|root,arCOG00417@2157|Archaea,2XTI2@28890|Euryarchaeota,2N9KC@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange	radB	-	-	ko:K04484	-	-	-	-	ko00000,ko03400	-	-	-	Rad51
GGS1_k127_558147_1	477974.Daud_1540	8.248e-52	196.0	COG1117@1|root,COG1117@2|Bacteria,1UJJD@1239|Firmicutes,25F4F@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
GGS1_k127_558147_2	351160.RCIX664	2.139e-50	188.0	COG4662@1|root,arCOG00166@2157|Archaea,2XTDY@28890|Euryarchaeota,2N9K0@224756|Methanomicrobia	224756|Methanomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
GGS1_k127_558147_0	1128421.JAGA01000001_gene2167	1.01e-59	218.0	COG2998@1|root,COG2998@2|Bacteria,2NP4U@2323|unclassified Bacteria	2|Bacteria	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
GGS1_k127_558147_3	1184251.TCELL_0773	2.133e-15	84.0	COG0456@1|root,arCOG00833@2157|Archaea,2XR31@28889|Crenarchaeota	28889|Crenarchaeota	K	TIGRFAM ribosomal-protein-alanine acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GGS1_k127_563304_1	404589.Anae109_2479	8.316e-32	129.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GGS1_k127_563304_0	1227500.C494_09760	1.368e-35	151.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,23S4H@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GGS1_k127_563665_0	1122939.ATUD01000001_gene459	5.422e-44	172.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4CQAU@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
GGS1_k127_563665_1	861299.J421_3108	7.401e-32	141.0	2F044@1|root,33T7T@2|Bacteria,1ZTDC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_570045_0	1125863.JAFN01000001_gene1462	2.019e-178	571.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GGS1_k127_570045_1	1343739.PAP_08705	9.36e-12	73.0	COG1522@1|root,arCOG01585@2157|Archaea,2XW1H@28890|Euryarchaeota,242Y6@183968|Thermococci	183968|Thermococci	K	Archaeal TRASH domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_24
GGS1_k127_571883_0	439481.Aboo_0779	2.579e-14	88.0	COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03607@2157|Archaea	2157|Archaea	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,Big_3_5,NosD,PKD,Peptidase_C1,S_layer_C
GGS1_k127_580321_0	930945.SiRe_1153	2.891e-116	390.0	COG2511@1|root,arCOG01719@2157|Archaea,2XPPH@28889|Crenarchaeota	28889|Crenarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
GGS1_k127_580321_1	342949.PNA2_0049	3.37e-114	382.0	COG0252@1|root,arCOG01924@2157|Archaea,2XTN1@28890|Euryarchaeota,2439K@183968|Thermococci	183968|Thermococci	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
GGS1_k127_5881_5	439481.Aboo_1103	5.187e-21	100.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,3F2ID@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	helicase superfamily c-terminal domain	hef	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C,ResIII
GGS1_k127_5881_1	1163617.SCD_n01466	1.516e-99	363.0	COG0745@1|root,COG3829@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VP0K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
GGS1_k127_5881_2	1382306.JNIM01000001_gene4190	4.109e-98	348.0	COG0863@1|root,COG0863@2|Bacteria,2G650@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GGS1_k127_5881_3	1173020.Cha6605_4905	2.66e-62	237.0	COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GGS1_k127_5881_4	1121403.AUCV01000013_gene3928	4.713e-59	219.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2MKTX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GGS1_k127_5881_0	118173.KB235914_gene1175	2.04e-101	346.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GGS1_k127_609190_1	290397.Adeh_1957	8.204e-36	141.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2WMQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GGS1_k127_609190_0	572478.Vdis_2279	4.467e-217	704.0	COG1148@1|root,arCOG02235@2157|Archaea,arCOG02236@2157|Archaea,2XS2Y@28889|Crenarchaeota	28889|Crenarchaeota	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,FlpD,Pyr_redox_2
GGS1_k127_610401_4	1132441.KI519454_gene1056	2.075e-35	144.0	COG3371@1|root,COG3371@2|Bacteria	2|Bacteria	KLT	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GGS1_k127_610401_1	1132509.C447_13612	1.349e-90	314.0	COG0842@1|root,arCOG01467@2157|Archaea,2XZAA@28890|Euryarchaeota,23ZEN@183963|Halobacteria	183963|Halobacteria	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
GGS1_k127_610401_0	1123024.AUII01000025_gene2106	3.222e-120	404.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	drrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GGS1_k127_610401_6	37919.EP51_34710	0.0002096	53.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,4G11R@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GGS1_k127_610401_5	926560.KE387027_gene707	1.692e-23	115.0	COG1765@1|root,COG1765@2|Bacteria,1WM1H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GGS1_k127_610401_3	797299.HALLA_00875	6.105e-37	142.0	COG0640@1|root,arCOG01681@2157|Archaea,2XYB2@28890|Euryarchaeota,23WKI@183963|Halobacteria	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GGS1_k127_610401_2	1268622.AVS7_01226	2.488e-42	159.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,4ADZG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GGS1_k127_631404_2	1172181.KB911701_gene1159	0.0003593	52.0	2F4UZ@1|root,33XHA@2|Bacteria,2IGIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_631404_0	573064.Mefer_0731	6.605e-25	113.0	COG0503@1|root,arCOG00030@2157|Archaea,2XTWM@28890|Euryarchaeota,23Q0J@183939|Methanococci	183939|Methanococci	F	Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GGS1_k127_631404_1	797114.C475_00762	4.887e-10	70.0	COG2730@1|root,arCOG09007@2157|Archaea,2XW9H@28890|Euryarchaeota,23TFT@183963|Halobacteria	183963|Halobacteria	G	Carbohydrate binding family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,fn3
GGS1_k127_632065_1	1236689.MMALV_01600	2.029e-46	178.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,3F2KP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	rpa1	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
GGS1_k127_632065_0	279010.BL03658	4.978e-78	268.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,1ZPZV@1386|Bacillus	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GGS1_k127_663031_0	1041138.KB890221_gene1076	2.137e-80	271.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,4B7KK@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	MA20_09775	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
GGS1_k127_663031_1	1122612.AUBA01000002_gene1752	7.864e-25	117.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,2UFG6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GGS1_k127_665381_0	439481.Aboo_1323	6.442e-69	246.0	COG1577@1|root,arCOG01028@2157|Archaea,2XSUB@28890|Euryarchaeota,3F2JQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GGS1_k127_665381_1	439481.Aboo_0606	1.894e-66	233.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,3F2M8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
GGS1_k127_665381_3	1379281.AVAG01000047_gene349	9.252e-32	138.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2M8RV@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GGS1_k127_665381_2	880073.Calab_0813	2.347e-59	231.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
GGS1_k127_689033_0	406124.ACPC01000017_gene625	9.782e-60	227.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
GGS1_k127_694175_1	439481.Aboo_0070	6.184e-68	235.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,3F2K0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GGS1_k127_694175_2	693661.Arcve_1347	1.355e-58	216.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,245YE@183980|Archaeoglobi	183980|Archaeoglobi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GGS1_k127_694175_0	439481.Aboo_0072	5.745e-192	608.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,3F2GN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GGS1_k127_698119_1	797209.ZOD2009_07064	1.203e-17	90.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,23UR0@183963|Halobacteria	183963|Halobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24
GGS1_k127_698119_0	205922.Pfl01_0700	5.664e-21	109.0	COG5029@1|root,COG5029@2|Bacteria	2|Bacteria	O	Prenyltransferase	-	-	2.5.1.60	ko:K05956	-	-	-	-	ko00000,ko01000,ko01006,ko04131	-	-	-	Prenyltrans
GGS1_k127_70450_3	439481.Aboo_1171	8.37e-72	250.0	COG1100@1|root,arCOG01225@2157|Archaea,2XWN4@28890|Euryarchaeota,3F2J6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
GGS1_k127_70450_2	387631.Asulf_00744	1.309e-72	253.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,2463Z@183980|Archaeoglobi	183980|Archaeoglobi	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
GGS1_k127_70450_4	1033734.CAET01000088_gene3694	4.889e-42	158.0	COG0454@1|root,COG0454@2|Bacteria,1V6N8@1239|Firmicutes,4HITB@91061|Bacilli,1ZH2H@1386|Bacillus	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GGS1_k127_70450_8	694440.JOMF01000005_gene144	3.815e-06	50.0	COG2260@1|root,arCOG00906@2157|Archaea	2157|Archaea	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
GGS1_k127_70450_1	439481.Aboo_1152	6.57e-82	279.0	COG1093@1|root,arCOG04107@2157|Archaea,2XTV0@28890|Euryarchaeota,3F2GS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2a	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
GGS1_k127_70450_6	456442.Mboo_1952	9.053e-13	74.0	COG2051@1|root,arCOG04108@2157|Archaea,2XZW2@28890|Euryarchaeota,2NA0J@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM Ribosomal protein S27E	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
GGS1_k127_70450_5	1236689.MMALV_02790	7.64e-30	121.0	COG1631@1|root,arCOG04109@2157|Archaea,2XXV3@28890|Euryarchaeota,3F2Q7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl44e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
GGS1_k127_70450_0	525904.Tter_2199	3.399e-85	292.0	COG2227@1|root,COG2227@2|Bacteria,2NRF7@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
GGS1_k127_70450_7	1463841.JOIR01000005_gene5106	1.955e-07	62.0	COG0454@1|root,COG0456@2|Bacteria,2GKQU@201174|Actinobacteria	201174|Actinobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
GGS1_k127_70450_9	1183377.Py04_0437	5.769e-06	48.0	COG2151@1|root,arCOG01845@2157|Archaea,2Y0P6@28890|Euryarchaeota,243HE@183968|Thermococci	183968|Thermococci	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GGS1_k127_707684_1	485913.Krac_0576	6.719e-92	310.0	COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GGS1_k127_707684_0	439481.Aboo_0457	3.223e-145	471.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
GGS1_k127_714584_5	410358.Mlab_0039	1.278e-17	90.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,2N94I@224756|Methanomicrobia	224756|Methanomicrobia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GGS1_k127_714584_1	673860.AciM339_0770	1.001e-51	194.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,3F2P4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
GGS1_k127_714584_3	644282.Deba_2699	3.173e-40	162.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GGS1_k127_714584_2	224325.AF_1728	8.318e-51	198.0	COG0438@1|root,arCOG01403@2157|Archaea,2XVAJ@28890|Euryarchaeota,245P8@183980|Archaeoglobi	183980|Archaeoglobi	M	Glycosyltransferase Family 4	-	-	2.4.1.87	ko:K00743	ko00601,map00601	-	R05978,R06169	-	ko00000,ko00001,ko01000,ko01003	-	GT6	-	Glyco_transf_4,Glycos_transf_1
GGS1_k127_714584_0	565033.GACE_1114	1.93e-94	324.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,245ZX@183980|Archaeoglobi	183980|Archaeoglobi	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GGS1_k127_714584_4	1236689.MMALV_15520	9.703e-24	103.0	arCOG14617@1|root,arCOG14617@2157|Archaea,2Y5TW@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_726688_0	240015.ACP_0267	1.12e-189	616.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GGS1_k127_726688_2	1457250.BBMO01000002_gene2994	2.724e-37	158.0	arCOG01781@1|root,arCOG01781@2157|Archaea,2XSY0@28890|Euryarchaeota,23RWZ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	scm	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GGS1_k127_726688_3	1236902.ANAS01000041_gene4348	3.347e-17	94.0	COG1011@1|root,COG1011@2|Bacteria,2GPJ4@201174|Actinobacteria,4EGYK@85012|Streptosporangiales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase,Hydrolase_like
GGS1_k127_726688_1	1038859.AXAU01000014_gene1378	1.222e-123	415.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GGS1_k127_730376_0	243232.MJ_0985	8.005e-91	309.0	COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota,23RNE@183939|Methanococci	183939|Methanococci	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GGS1_k127_730376_3	694440.JOMF01000004_gene1164	0.0001416	53.0	arCOG02421@1|root,arCOG02421@2157|Archaea	2157|Archaea	S	TIGRFAM archaeal flagellin N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
GGS1_k127_730376_2	29540.C481_09467	8.272e-05	52.0	arCOG02416@1|root,arCOG02416@2157|Archaea	2157|Archaea	S	Archaeal Type IV pilin, N-terminal	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PKD,Pilin_N
GGS1_k127_730376_1	269797.Mbar_A0979	1.125e-19	91.0	COG1916@1|root,arCOG02142@2157|Archaea,2XTNE@28890|Euryarchaeota,2N97A@224756|Methanomicrobia	224756|Methanomicrobia	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
GGS1_k127_731810_5	224324.aq_759	1.186e-06	55.0	COG1730@1|root,COG1730@2|Bacteria,2G46Z@200783|Aquificae	200783|Aquificae	O	Prefoldin subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
GGS1_k127_731810_0	1183377.Py04_1556	1.097e-94	324.0	COG0552@1|root,arCOG01227@2157|Archaea,2XUBI@28890|Euryarchaeota,242QW@183968|Thermococci	183968|Thermococci	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GGS1_k127_731810_1	644966.Tmar_2066	6.378e-74	267.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WD3T@538999|Clostridiales incertae sedis	186801|Clostridia	L	PFAM HhH-GPD superfamily base excision DNA repair protein	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
GGS1_k127_731810_2	269800.Tfu_1230	1.208e-22	106.0	COG0702@1|root,COG0702@2|Bacteria,2I234@201174|Actinobacteria,4EP52@85012|Streptosporangiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GGS1_k127_731810_3	1094980.Mpsy_1328	5.213e-14	74.0	COG1552@1|root,arCOG04049@2157|Archaea,2Y177@28890|Euryarchaeota,2NB9F@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL40 family	rpl40e	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e
GGS1_k127_731810_4	643648.Slip_0649	4.922e-11	74.0	COG1266@1|root,COG1266@2|Bacteria,1UUMR@1239|Firmicutes,25CF0@186801|Clostridia,42KPQ@68298|Syntrophomonadaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GGS1_k127_744124_0	1054217.TALC_01299	2.584e-98	343.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,241MK@183967|Thermoplasmata	183967|Thermoplasmata	J	DALR anticodon binding domain	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	DALR_1,tRNA-synt_1d
GGS1_k127_744124_1	743836.AYNA01000104_gene2059	2.577e-40	165.0	COG1215@1|root,COG1215@2|Bacteria,1R8UT@1224|Proteobacteria,2TVQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
GGS1_k127_747474_1	289377.HL41_02390	2.739e-126	431.0	COG2414@1|root,COG2414@2|Bacteria,2GGWI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GGS1_k127_747474_5	69014.TK0213	2.389e-05	53.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244HA@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GGS1_k127_747474_4	869210.Marky_1547	4.825e-37	151.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
GGS1_k127_747474_2	410359.Pcal_0560	2.862e-85	299.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GGS1_k127_747474_0	644966.Tmar_1485	1.69e-151	498.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3WDC4@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GGS1_k127_747474_3	1382306.JNIM01000001_gene2674	1.152e-82	279.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GGS1_k127_75245_1	1054217.TALC_00428	4.183e-29	116.0	COG0100@1|root,arCOG04240@2157|Archaea,2XX1S@28890|Euryarchaeota,241PM@183967|Thermoplasmata	183967|Thermoplasmata	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GGS1_k127_75245_0	1236689.MMALV_03530	2.696e-68	241.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,3F2KY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Fer4,RNA_pol_A_bac,RNA_pol_L
GGS1_k127_767478_1	439481.Aboo_0007	1.721e-39	151.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F36C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
GGS1_k127_767478_0	439481.Aboo_0008	2e-61	224.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F37F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
GGS1_k127_767478_2	658086.HMPREF0994_03571	5.661e-09	69.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,27KEU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Glyco_hydro_79n
GGS1_k127_770475_2	1449063.JMLS01000015_gene1046	3.378e-10	70.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,4HM8K@91061|Bacilli,26VN7@186822|Paenibacillaceae	91061|Bacilli	E	COG4886 Leucine-rich repeat (LRR) protein	inlA	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030260,GO:0030312,GO:0035635,GO:0044403,GO:0044409,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	-	ko:K13730,ko:K13731	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Flg_new,Gram_pos_anchor,Internalin_N,LRR_4,LRR_6,LRR_adjacent,NEAT,SLH,Strep_his_triad,fn3
GGS1_k127_770475_1	391038.Bphy_5223	1.375e-43	166.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,1K3AS@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GGS1_k127_770475_0	251221.35211388	2.003e-96	331.0	COG4398@1|root,COG4398@2|Bacteria,1G0TB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GGS1_k127_770475_3	1227497.C491_06928	6.96e-07	55.0	arCOG07990@1|root,arCOG07990@2157|Archaea,2XZ08@28890|Euryarchaeota,23X6V@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_778535_4	593117.TGAM_1681	4.986e-07	53.0	COG2157@1|root,arCOG04175@2157|Archaea,2Y0R1@28890|Euryarchaeota,244JC@183968|Thermococci	183968|Thermococci	J	rRNA binding	rplX	-	-	ko:K02944	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18A
GGS1_k127_778535_3	1094980.Mpsy_1566	3.195e-52	196.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
GGS1_k127_778535_2	269797.Mbar_A1372	2.542e-57	207.0	COG1601@1|root,arCOG01640@2157|Archaea,2XTVZ@28890|Euryarchaeota,2N9JI@224756|Methanomicrobia	224756|Methanomicrobia	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
GGS1_k127_778535_0	1408254.T458_05535	5.656e-188	612.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GGS1_k127_778535_1	1209072.ALBT01000053_gene467	2.133e-66	247.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1FHR7@10|Cellvibrio	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
GGS1_k127_785077_1	1123508.JH636442_gene3920	8.439e-10	67.0	COG0399@1|root,COG0399@2|Bacteria,2IZ4J@203682|Planctomycetes	203682|Planctomycetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GGS1_k127_785077_2	593750.Metfor_0422	2.594e-08	57.0	arCOG04501@1|root,arCOG04501@2157|Archaea	2157|Archaea	S	COG2002 Regulators of stationary sporulation gene expression	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GGS1_k127_785077_0	1292020.H483_0113865	8.412e-64	230.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GGS1_k127_794328_1	368407.Memar_0794	1.442e-17	98.0	COG2319@1|root,arCOG02491@2157|Archaea,2XZY9@28890|Euryarchaeota,2NB16@224756|Methanomicrobia	224756|Methanomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,WD40
GGS1_k127_794328_0	523850.TON_1432	7.031e-180	573.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
GGS1_k127_807620_6	290397.Adeh_0540	2.371e-14	86.0	COG0400@1|root,COG0400@2|Bacteria,1REBB@1224|Proteobacteria,431D3@68525|delta/epsilon subdivisions,2WX1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GGS1_k127_807620_2	439235.Dalk_1202	2.255e-63	225.0	COG0346@1|root,COG0346@2|Bacteria,1PM7Y@1224|Proteobacteria,42RD3@68525|delta/epsilon subdivisions,2WNY7@28221|Deltaproteobacteria,2MJSI@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_807620_3	402626.Rpic_3832	1.043e-56	207.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2VM6S@28216|Betaproteobacteria,1K3I3@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	abmB	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.30	ko:K00019,ko:K07535	ko00072,ko00362,ko00650,ko01100,ko01120,ko01220,map00072,map00362,map00650,map01100,map01120,map01220	M00088,M00540	R01361,R05582	RC00117,RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
GGS1_k127_807620_4	1192034.CAP_0944	2.208e-23	113.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,434U0@68525|delta/epsilon subdivisions,2WZ4Y@28221|Deltaproteobacteria,2Z1C7@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GGS1_k127_807620_1	266117.Rxyl_2277	2.795e-72	258.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4CQ6Y@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GGS1_k127_807620_0	1122221.JHVI01000003_gene380	1.064e-85	299.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GGS1_k127_807620_5	1121374.KB891579_gene1779	1.882e-21	110.0	COG2931@1|root,COG2931@2|Bacteria,1R0AU@1224|Proteobacteria,1S2TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_814845_0	1236689.MMALV_07510	3.959e-61	215.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,3F34R@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Archaeal Nre, N-terminal	nreA	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
GGS1_k127_814845_1	439481.Aboo_0739	2.791e-43	171.0	COG1533@1|root,arCOG01290@2157|Archaea,2XY2A@28890|Euryarchaeota,3F2Q3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GGS1_k127_814845_2	368407.Memar_2020	9.189e-16	80.0	COG0642@1|root,arCOG02346@1|root,arCOG06516@1|root,arCOG02346@2157|Archaea,arCOG06192@2157|Archaea,arCOG06516@2157|Archaea	2157|Archaea	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GGS1_k127_817173_0	292459.STH972	3.341e-47	175.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes	1239|Firmicutes	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
GGS1_k127_817173_2	69293.ENSGACP00000011739	4.234e-06	58.0	COG0494@1|root,KOG2839@2759|Eukaryota,3A2WK@33154|Opisthokonta,3BRRM@33208|Metazoa,3D6EC@33213|Bilateria,48A53@7711|Chordata,498F7@7742|Vertebrata,4A3JG@7898|Actinopterygii	33208|Metazoa	T	Nudix (nucleoside diphosphate linked moiety X)-type motif 2	NUDT2	GO:0003674,GO:0003824,GO:0004081,GO:0004551,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006172,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0008150,GO:0008152,GO:0008219,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012501,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043135,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046033,GO:0046034,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.6.1.17	ko:K01518	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GGS1_k127_817173_1	555079.Toce_1907	7.399e-08	59.0	2E6A2@1|root,330XY@2|Bacteria,1U5UB@1239|Firmicutes,25NDK@186801|Clostridia,42IJU@68295|Thermoanaerobacterales	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
GGS1_k127_81967_1	1038859.AXAU01000011_gene2414	4.41e-16	82.0	COG3070@1|root,COG3070@2|Bacteria,1P6Z6@1224|Proteobacteria	1224|Proteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
GGS1_k127_81967_3	243233.MCA3064	7.937e-07	54.0	2EQEC@1|root,33I0C@2|Bacteria,1NP5N@1224|Proteobacteria,1SGGK@1236|Gammaproteobacteria,1XGVA@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_81967_0	868131.MSWAN_2284	2.825e-80	279.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,23NUP@183925|Methanobacteria	183925|Methanobacteria	J	Diphthamide	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
GGS1_k127_81967_2	644283.Micau_1672	8.551e-08	66.0	COG5297@1|root,COG5297@2|Bacteria,2IAE1@201174|Actinobacteria,4D9WW@85008|Micromonosporales	201174|Actinobacteria	G	Cellulose binding domain	-	-	3.2.1.11,3.2.1.4	ko:K01179,ko:K05988	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308,R11309	-	ko00000,ko00001,ko01000	-	GH5,GH66,GH9	-	CBM_2,CBM_3,Glyco_hydro_9,fn3
GGS1_k127_826231_0	1480694.DC28_11195	0.0002907	53.0	2FFB7@1|root,3478X@2|Bacteria,2J8CB@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_832922_0	565033.GACE_0766	1.666e-108	364.0	COG0183@1|root,arCOG01278@2157|Archaea,2XVUA@28890|Euryarchaeota,2460R@183980|Archaeoglobi	183980|Archaeoglobi	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GGS1_k127_832922_2	192952.MM_2604	1.111e-07	55.0	arCOG10361@1|root,arCOG10361@2157|Archaea,2Y5Z6@28890|Euryarchaeota,2NBEF@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_832922_3	192952.MM_2605	1.179e-05	52.0	COG2026@1|root,arCOG01665@2157|Archaea	2157|Archaea	DJ	PFAM plasmid stabilization system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GGS1_k127_832922_1	452637.Oter_2033	1.465e-88	313.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
GGS1_k127_836487_4	192952.MM_1403	2.076e-17	91.0	COG1183@1|root,arCOG00671@2157|Archaea,2XT0G@28890|Euryarchaeota,2NAYG@224756|Methanomicrobia	224756|Methanomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0874	CDP-OH_P_transf
GGS1_k127_836487_1	439481.Aboo_0296	7.194e-61	216.0	COG1618@1|root,arCOG01034@2157|Archaea,2XX6U@28890|Euryarchaeota,3F2MF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
GGS1_k127_836487_3	1220534.B655_1721	1.06e-46	189.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,23NVN@183925|Methanobacteria	183925|Methanobacteria	J	Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups	trm1	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
GGS1_k127_836487_0	186497.PF1387	3.63e-66	235.0	COG1701@1|root,arCOG04262@2157|Archaea,2XTAP@28890|Euryarchaeota,243IV@183968|Thermococci	183968|Thermococci	S	Phosphopantothenate/pantothenate synthetase	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
GGS1_k127_836487_2	1173023.KE650771_gene598	5.868e-53	211.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1JK6S@1189|Stigonemataceae	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
GGS1_k127_840952_0	1380394.JADL01000024_gene101	0.0	1052.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
GGS1_k127_867566_10	572546.Arcpr_1106	1.226e-05	56.0	arCOG06689@1|root,arCOG06689@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,SpoIIM
GGS1_k127_867566_8	572546.Arcpr_1106	2.491e-08	64.0	arCOG06689@1|root,arCOG06689@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,SpoIIM
GGS1_k127_867566_2	565033.GACE_0364	1.097e-55	204.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GGS1_k127_867566_1	351160.RCIX2726	2.627e-82	302.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Beta propeller domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Beta_propel,Inhibitor_I42
GGS1_k127_867566_12	926690.KE386573_gene1816	0.0001601	48.0	arCOG07990@1|root,arCOG07990@2157|Archaea,2XZBP@28890|Euryarchaeota,23X0K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_867566_7	1457250.BBMO01000003_gene3050	1.112e-16	89.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GGS1_k127_867566_3	1205753.A989_19258	3.448e-43	181.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1X4P1@135614|Xanthomonadales	135614|Xanthomonadales	O	Cytochrome C biogenesis	ccmF2	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GGS1_k127_867566_11	1293047.CBMA010000008_gene246	6.07e-05	53.0	COG2512@1|root,arCOG00386@2157|Archaea,2XZKM@28890|Euryarchaeota,23W4D@183963|Halobacteria	183963|Halobacteria	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
GGS1_k127_867566_4	926560.KE387025_gene3986	2.244e-27	117.0	COG4263@1|root,COG4263@2|Bacteria,1WKG1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GGS1_k127_867566_5	694440.JOMF01000008_gene1053	5.268e-26	120.0	COG0785@1|root,arCOG02400@2157|Archaea,2Y0J2@28890|Euryarchaeota,2NBK2@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
GGS1_k127_867566_6	479433.Caci_2525	1.162e-17	98.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
GGS1_k127_867566_0	529709.PYCH_09250	1.674e-165	533.0	COG0008@1|root,arCOG00402@2157|Archaea,2XSUM@28890|Euryarchaeota,242RZ@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GGS1_k127_867566_9	479432.Sros_0349	1.405e-06	54.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4ENKU@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GGS1_k127_877193_1	1396858.Q666_00095	5.46e-06	48.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,468WQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
GGS1_k127_877193_0	452637.Oter_3066	5.946e-19	103.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DctA-YdbH
GGS1_k127_880338_1	521011.Mpal_1938	7.229e-32	128.0	COG0301@1|root,arCOG00038@2157|Archaea,2XYMB@28890|Euryarchaeota,2NBHY@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI
GGS1_k127_880338_3	456442.Mboo_1986	0.0005371	47.0	arCOG09483@1|root,arCOG09483@2157|Archaea	2157|Archaea	-	-	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
GGS1_k127_880338_2	1159870.KB907784_gene1819	5.914e-19	94.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2VS8Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GGS1_k127_880338_0	374847.Kcr_0400	8.793e-41	165.0	COG1759@1|root,arCOG04346@2157|Archaea	2157|Archaea	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
GGS1_k127_892984_0	324602.Caur_0272	1.951e-50	185.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,376NC@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GGS1_k127_892984_1	304371.MCP_1106	1.438e-24	119.0	COG1668@1|root,arCOG01462@2157|Archaea,2Y3YK@28890|Euryarchaeota	28890|Euryarchaeota	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GGS1_k127_892984_2	1033806.HTIA_1884	2.777e-09	67.0	COG0526@1|root,arCOG01218@2157|Archaea,2XY63@28890|Euryarchaeota,23Z00@183963|Halobacteria	183963|Halobacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GGS1_k127_892984_3	298655.KI912266_gene2633	4.215e-07	55.0	COG2020@1|root,COG2020@2|Bacteria,2IE57@201174|Actinobacteria,4EUXN@85013|Frankiales	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GGS1_k127_913645_1	671143.DAMO_0872	1.525e-32	147.0	COG2267@1|root,COG2267@2|Bacteria,2NRR1@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GGS1_k127_913645_0	415426.Hbut_1592	1.894e-42	166.0	COG1756@1|root,arCOG04122@2157|Archaea,2XQJ6@28889|Crenarchaeota	28889|Crenarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
GGS1_k127_920660_0	673860.AciM339_1255	2.578e-90	310.0	COG0148@1|root,arCOG01169@2157|Archaea,2XSXT@28890|Euryarchaeota,3F2J7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GGS1_k127_920660_1	1054217.TALC_00320	7.936e-54	203.0	COG0162@1|root,arCOG01886@2157|Archaea,2XTA0@28890|Euryarchaeota,241NP@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
GGS1_k127_947404_0	565033.GACE_0972	9.995e-39	162.0	COG0467@1|root,arCOG01174@2157|Archaea,2XV95@28890|Euryarchaeota,246T5@183980|Archaeoglobi	183980|Archaeoglobi	T	DnaB-like helicase C terminal domain	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GGS1_k127_947404_2	292459.STH2355	1.777e-07	64.0	COG0467@1|root,COG0467@2|Bacteria,1TSIM@1239|Firmicutes,24DRY@186801|Clostridia	186801|Clostridia	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GGS1_k127_947404_1	1459636.NTE_00594	1.704e-21	101.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T38@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GGS1_k127_955792_4	357808.RoseRS_4184	3.332e-13	78.0	COG0863@1|root,COG0863@2|Bacteria,2G6M6@200795|Chloroflexi,376YY@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GGS1_k127_955792_2	1229172.JQFA01000002_gene3797	2.434e-50	183.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GGS1_k127_955792_0	1173027.Mic7113_3423	1.191e-85	304.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,1H88F@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GGS1_k127_955792_3	309801.trd_A0075	4.577e-22	112.0	COG0574@1|root,COG0574@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GGS1_k127_955792_1	351160.RCIX1996	6.793e-54	194.0	COG0197@1|root,arCOG04113@2157|Archaea,2XTHT@28890|Euryarchaeota,2N9MZ@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the universal ribosomal protein uL16 family	rpl10e	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
GGS1_k127_962656_0	1183377.Py04_0245	2.607e-81	284.0	COG2896@1|root,arCOG00930@2157|Archaea,2XT7P@28890|Euryarchaeota,242JX@183968|Thermococci	183968|Thermococci	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GGS1_k127_962656_1	1173024.KI912148_gene2957	1.498e-05	54.0	COG0457@1|root,COG3206@1|root,COG0457@2|Bacteria,COG3206@2|Bacteria,1G1U5@1117|Cyanobacteria,1JHI2@1189|Stigonemataceae	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GGS1_k127_979998_0	358396.C445_01666	8.16e-92	316.0	COG0446@1|root,arCOG01070@2157|Archaea,2XTPB@28890|Euryarchaeota,23TGY@183963|Halobacteria	183963|Halobacteria	S	NAD(FAD)-dependent dehydrogenases	noxA2	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
GGS1_k127_979998_1	926560.KE387025_gene4075	0.0002138	50.0	2B5RU@1|root,31YMF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GGS1_k127_980085_1	1191523.MROS_0441	2.27e-58	211.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GGS1_k127_980085_2	1380390.JIAT01000010_gene3976	3.721e-09	66.0	COG0723@1|root,COG0723@2|Bacteria,2HGHS@201174|Actinobacteria,4CTW3@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
GGS1_k127_980085_0	1236689.MMALV_00370	2.665e-88	294.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,3F2I1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAB	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF692.Mbar_A1178	GMP_synt_C,NAD_synthase
## 1744 queries scanned
## Total time (seconds): 32.980414628982544
## Rate: 52.88 q/s