## Wed Oct 16 15:29:52 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/GNS2_bin.35.fa -m mmseqs --itype genome -o GNS2_bin.35 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/GNS2_bin.35 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GNS2_k127_100145_14	1121428.DESHY_110543___1	3.774e-16	90.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,2627P@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
GNS2_k127_100145_12	204669.Acid345_4135	5.336e-26	115.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria,2JK2N@204432|Acidobacteriia	204432|Acidobacteriia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GNS2_k127_100145_4	204669.Acid345_0023	5.068e-86	301.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia	57723|Acidobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
GNS2_k127_100145_13	1340493.JNIF01000003_gene2554	1.116e-20	103.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GNS2_k127_100145_9	886293.Sinac_7289	2.686e-37	160.0	COG1057@1|root,COG1057@2|Bacteria,2IZMU@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GNS2_k127_100145_3	1123371.ATXH01000006_gene840	4.176e-113	374.0	COG0536@1|root,COG0536@2|Bacteria,2GHPW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
GNS2_k127_100145_10	28072.Nos7524_5355	5.094e-30	122.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HNYF@1161|Nostocales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GNS2_k127_100145_11	936589.HMPREF1521_0609	6.053e-27	113.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4H4VN@909932|Negativicutes	909932|Negativicutes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GNS2_k127_100145_7	1047013.AQSP01000115_gene336	2.474e-43	170.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
GNS2_k127_100145_2	1047013.AQSP01000115_gene336	3.548e-134	461.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
GNS2_k127_100145_15	420662.Mpe_A1226	5.802e-06	53.0	COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,2W9UY@28216|Betaproteobacteria,1KNVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
GNS2_k127_100145_6	886293.Sinac_6401	7.114e-73	264.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,2IX3D@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
GNS2_k127_100145_0	404589.Anae109_2693	4.341e-251	798.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GNS2_k127_100145_1	1121468.AUBR01000036_gene1297	6.745e-161	528.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,42ESP@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GNS2_k127_100145_5	443144.GM21_0487	1.183e-82	286.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GNS2_k127_100145_8	767817.Desgi_1265	1.252e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_1004537_1	1267535.KB906767_gene2409	1.62e-46	179.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria,2JI45@204432|Acidobacteriia	204432|Acidobacteriia	M	penicillin-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
GNS2_k127_1004537_2	670487.Ocepr_0461	3.778e-10	72.0	COG3895@1|root,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
GNS2_k127_1004537_0	671143.DAMO_1646	2.53e-94	332.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GNS2_k127_1013968_0	1499967.BAYZ01000095_gene4168	1.921e-22	103.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
GNS2_k127_1013968_2	1304880.JAGB01000002_gene2264	3.568e-08	66.0	2DBSS@1|root,2ZATI@2|Bacteria,1V13H@1239|Firmicutes,24D92@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
GNS2_k127_1013968_1	1278073.MYSTI_06129	1.209e-16	84.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,42XMG@68525|delta/epsilon subdivisions,2WSJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GNS2_k127_1022239_3	340177.Cag_1581	4.27e-87	298.0	COG0598@1|root,COG0598@2|Bacteria,1FEBZ@1090|Chlorobi	1090|Chlorobi	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
GNS2_k127_1022239_7	1122939.ATUD01000001_gene217	7.156e-08	57.0	COG3237@1|root,COG3237@2|Bacteria,2HPFB@201174|Actinobacteria,4CQTP@84995|Rubrobacteria	84995|Rubrobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GNS2_k127_1022239_4	479432.Sros_6527	5.255e-37	141.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4EKBJ@85012|Streptosporangiales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
GNS2_k127_1022239_0	365046.Rta_06020	4.083e-129	419.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1022239_2	306281.AJLK01000091_gene3538	5.235e-105	352.0	COG1526@1|root,COG1526@2|Bacteria,1G2ZE@1117|Cyanobacteria,1JIDZ@1189|Stigonemataceae	1117|Cyanobacteria	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
GNS2_k127_1022239_1	1121918.ARWE01000001_gene1548	1.585e-113	396.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GNS2_k127_1022239_6	404589.Anae109_4151	9.65e-34	151.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
GNS2_k127_1022239_5	1396418.BATQ01000106_gene5355	3.375e-34	141.0	COG3794@1|root,COG3794@2|Bacteria,46SUG@74201|Verrucomicrobia,2IVQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1107507_4	485913.Krac_10080	2.339e-23	109.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GNS2_k127_1107507_5	204669.Acid345_1853	4.658e-23	104.0	2EBAA@1|root,335AW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
GNS2_k127_1107507_1	1297742.A176_05605	2.245e-237	768.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,437VH@68525|delta/epsilon subdivisions,2X354@28221|Deltaproteobacteria,2YUAY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
GNS2_k127_1107507_2	330214.NIDE2516	1.392e-100	339.0	COG0006@1|root,COG0006@2|Bacteria,3J0R0@40117|Nitrospirae	40117|Nitrospirae	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GNS2_k127_1107507_0	1128421.JAGA01000003_gene3737	5.225e-281	878.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	yoaE	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GNS2_k127_1107507_3	391625.PPSIR1_04398	1.947e-26	121.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
GNS2_k127_1107965_5	1122915.AUGY01000013_gene2877	1.417e-07	61.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4ISHD@91061|Bacilli,26SCF@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	F5_F8_type_C,GT87,PMT,PMT_2,PMT_4TMC
GNS2_k127_1107965_2	483219.LILAB_17160	2.249e-38	160.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GNS2_k127_1107965_1	290397.Adeh_0928	1.03e-86	312.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
GNS2_k127_1107965_0	1121346.KB899850_gene152	8.839e-107	376.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HEZ1@91061|Bacilli,275P2@186822|Paenibacillaceae	91061|Bacilli	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GNS2_k127_1107965_4	379066.GAU_3752	4.658e-08	63.0	2C6N0@1|root,30297@2|Bacteria,1ZV5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GNS2_k127_1107965_3	671143.DAMO_3041	1.45e-19	94.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
GNS2_k127_1115527_0	1120965.AUBV01000001_gene3486	3.825e-136	455.0	COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GNS2_k127_1115527_1	234267.Acid_0475	5.872e-106	346.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_1119920_1	323848.Nmul_A2137	2.266e-24	115.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,3723U@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GNS2_k127_1119920_0	357808.RoseRS_4419	1.978e-90	332.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi	200795|Chloroflexi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GNS2_k127_1119920_2	392499.Swit_3377	0.0007865	52.0	2DECI@1|root,32U34@2|Bacteria,1NFZ5@1224|Proteobacteria,2UN31@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GNS2_k127_1132477_2	234267.Acid_1770	4.496e-36	154.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
GNS2_k127_1132477_1	1128421.JAGA01000002_gene1230	8.558e-164	534.0	COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria	2|Bacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
GNS2_k127_1132477_0	518766.Rmar_0330	2.904e-240	778.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1FIX1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_1144591_1	357808.RoseRS_4058	2.403e-166	540.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,374YM@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GNS2_k127_1144591_10	935845.JADQ01000008_gene1833	1.377e-31	130.0	COG1246@1|root,COG1246@2|Bacteria,1V6TZ@1239|Firmicutes,4HID0@91061|Bacilli,26WS7@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate	argH1	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GNS2_k127_1144591_4	40149.OMERI05G02130.1	4.878e-106	368.0	COG4992@1|root,KOG1401@2759|Eukaryota,37JRF@33090|Viridiplantae,3GBNS@35493|Streptophyta,3KQ1V@4447|Liliopsida,3IBVS@38820|Poales	35493|Streptophyta	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0006950,GO:0006952,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0022622,GO:0030170,GO:0032501,GO:0032502,GO:0036094,GO:0042742,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044419,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048037,GO:0048364,GO:0048731,GO:0048856,GO:0050662,GO:0050896,GO:0051704,GO:0051707,GO:0070279,GO:0071704,GO:0080022,GO:0097159,GO:0098542,GO:0099402,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11	ko:K00818	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02283	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_1144591_8	89187.ISM_05290	1.368e-39	167.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,46P60@74030|Roseovarius	28211|Alphaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GNS2_k127_1144591_5	1125973.JNLC01000016_gene2883	1.016e-80	283.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,3JRRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GNS2_k127_1144591_2	204669.Acid345_1131	3.714e-166	531.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_1144591_11	1123288.SOV_2c08340	2.357e-24	119.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,4H4QE@909932|Negativicutes	909932|Negativicutes	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
GNS2_k127_1144591_6	1047013.AQSP01000028_gene2077	7.478e-59	212.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GNS2_k127_1144591_0	1267535.KB906767_gene3806	5.292e-282	878.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GNS2_k127_1144591_7	316067.Geob_3387	1.013e-43	163.0	COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,42YHD@68525|delta/epsilon subdivisions,2WU58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GNS2_k127_1144591_3	756499.Desde_3530	5.319e-107	368.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,2603B@186807|Peptococcaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
GNS2_k127_1144591_9	316067.Geob_3385	3.044e-35	156.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42QS2@68525|delta/epsilon subdivisions,2WMXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GNS2_k127_1178137_1	485913.Krac_7158	7.271e-78	269.0	COG0076@1|root,COG0076@2|Bacteria,2G8Q9@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GNS2_k127_1178137_0	1267534.KB906758_gene2265	7.342e-318	995.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
GNS2_k127_1206359_3	1121933.AUHH01000011_gene2723	0.0001856	53.0	COG3307@1|root,COG3307@2|Bacteria,2HZUX@201174|Actinobacteria,4DU62@85009|Propionibacteriales	201174|Actinobacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1206359_2	439235.Dalk_3698	0.0001325	54.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MKRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
GNS2_k127_1206359_0	565045.NOR51B_2671	2.537e-118	412.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria,1JBJG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
GNS2_k127_1219100_1	290397.Adeh_3001	3.901e-196	629.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
GNS2_k127_1219100_3	234267.Acid_5312	4.446e-25	106.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
GNS2_k127_1219100_0	204669.Acid345_0650	2.884e-242	774.0	COG1501@1|root,COG1501@2|Bacteria,3Y3EQ@57723|Acidobacteria,2JIBM@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
GNS2_k127_1219100_2	402626.Rpic_0139	2.144e-80	271.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,2VQHR@28216|Betaproteobacteria,1K074@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ferritin, Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
GNS2_k127_1252920_3	886293.Sinac_0323	3.184e-55	212.0	COG0438@1|root,COG0438@2|Bacteria,2IY3T@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_1252920_4	886293.Sinac_1743	9.682e-37	159.0	COG0438@1|root,COG0438@2|Bacteria,2J274@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GNS2_k127_1252920_1	2002.JOEQ01000038_gene4203	1.269e-169	552.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria	201174|Actinobacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GNS2_k127_1252920_5	443143.GM18_1575	1.721e-31	141.0	COG2244@1|root,COG2244@2|Bacteria,1NNBY@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
GNS2_k127_1252920_0	1192868.CAIU01000033_gene4239	9.085e-203	640.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2U1B2@28211|Alphaproteobacteria,43RF4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
GNS2_k127_1252920_2	926567.TheveDRAFT_1375	1.936e-71	254.0	COG4630@1|root,COG4630@2|Bacteria,3TAMB@508458|Synergistetes	508458|Synergistetes	C	CO dehydrogenase flavoprotein	-	-	1.17.1.4,1.2.5.3	ko:K03518,ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GNS2_k127_1259788_0	234267.Acid_5181	1.639e-233	738.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
GNS2_k127_1259788_1	1437824.BN940_06796	3.778e-77	263.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,3T905@506|Alcaligenaceae	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GNS2_k127_1259788_4	1121428.DESHY_110462___1	9.381e-20	92.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,263AU@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GNS2_k127_1259788_3	867903.ThesuDRAFT_00232	1.043e-23	109.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WDII@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GNS2_k127_1259788_2	215803.DB30_3504	5.653e-65	237.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
GNS2_k127_1259788_5	446470.Snas_4569	0.0009997	50.0	COG0346@1|root,COG0346@2|Bacteria,2GS59@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
GNS2_k127_126554_0	251229.Chro_2201	5.127e-147	496.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3VNFS@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GNS2_k127_126554_1	215803.DB30_0399	8.568e-78	264.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GNS2_k127_1320626_0	1144275.COCOR_02328	1.46e-134	432.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2Z30A@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_1320626_2	1128421.JAGA01000002_gene587	5.446e-76	272.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GNS2_k127_1320626_1	994573.T472_0203575	2.445e-84	306.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
GNS2_k127_1320626_3	1210884.HG799467_gene13174	1.344e-24	111.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_1329365_3	653045.Strvi_2414	1.74e-36	145.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria	201174|Actinobacteria	NU	MobA-related protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GNS2_k127_1329365_2	1340493.JNIF01000004_gene849	1.611e-64	231.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GNS2_k127_1329365_1	498761.HM1_2638	1.491e-66	244.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia	186801|Clostridia	H	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
GNS2_k127_1329365_0	589865.DaAHT2_2396	3.724e-81	286.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2MKRR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
GNS2_k127_1329365_4	457429.ABJI02000708_gene4281	3.516e-06	55.0	COG0484@1|root,COG0484@2|Bacteria,2GRB9@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
GNS2_k127_1356043_5	1453501.JELR01000002_gene580	4.836e-21	101.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,464D3@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	luxR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GNS2_k127_1356043_0	1158762.KB898039_gene1706	1.946e-101	357.0	COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg
GNS2_k127_1356043_4	215803.DB30_7269	1.044e-33	139.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,434K9@68525|delta/epsilon subdivisions,2WYXI@28221|Deltaproteobacteria,2Z0V9@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GNS2_k127_1356043_1	1430440.MGMSRv2_3724	6.482e-78	286.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JSNQ@204441|Rhodospirillales	204441|Rhodospirillales	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
GNS2_k127_1356043_6	1071073.KI530543_gene3020	5.731e-09	70.0	COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,1ZEMW@1386|Bacillus	91061|Bacilli	E	Lysine exporter protein LysE YggA	ycgF	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822	-	-	-	-	-	-	-	-	-	-	LysE
GNS2_k127_1356043_3	379066.GAU_2187	9.261e-47	171.0	COG0431@1|root,COG0431@2|Bacteria,1ZUYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
GNS2_k127_1391993_7	497964.CfE428DRAFT_0884	2.873e-18	89.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
GNS2_k127_1391993_3	404380.Gbem_1657	1.137e-113	390.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
GNS2_k127_1391993_2	1267533.KB906733_gene3460	4.592e-118	392.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GNS2_k127_1391993_4	869210.Marky_1204	8.842e-85	292.0	COG0491@1|root,COG0491@2|Bacteria,1WISH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GNS2_k127_1391993_0	204669.Acid345_2166	3.907e-225	707.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Dak2,DegV,Radical_SAM
GNS2_k127_1391993_6	1121468.AUBR01000096_gene781	4.69e-29	124.0	2AII4@1|root,31902@2|Bacteria,1VY3B@1239|Firmicutes,251KQ@186801|Clostridia,42IFA@68295|Thermoanaerobacterales	186801|Clostridia	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1391993_1	1192034.CAP_4834	3.235e-127	419.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YYK3@29|Myxococcales	28221|Deltaproteobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
GNS2_k127_1391993_5	1047013.AQSP01000003_gene2020	3.591e-69	239.0	COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
GNS2_k127_145566_0	251221.35213347	3.344e-143	469.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1G3PF@1117|Cyanobacteria	1117|Cyanobacteria	M	family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12,Methyltransf_23,Methyltransf_25
GNS2_k127_145566_4	1121406.JAEX01000002_gene1127	8.366e-39	157.0	COG0500@1|root,COG2226@2|Bacteria,1RFDN@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GNS2_k127_145566_6	720555.BATR1942_04675	3.593e-05	53.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZEK2@1386|Bacillus	91061|Bacilli	CO	thiol-disulfide	stoA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GNS2_k127_145566_3	204669.Acid345_1573	3.813e-40	168.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_145566_2	1265505.ATUG01000003_gene184	4.609e-47	181.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GNS2_k127_145566_1	197221.22295627	3.863e-81	281.0	COG1131@1|root,COG1131@2|Bacteria,1G0UC@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_145566_5	204669.Acid345_1569	1.044e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GNS2_k127_1459049_3	1121033.AUCF01000009_gene1115	2.239e-36	141.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V6M0@28211|Alphaproteobacteria,2JQRT@204441|Rhodospirillales	204441|Rhodospirillales	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
GNS2_k127_1459049_2	518766.Rmar_2587	7.568e-52	187.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
GNS2_k127_1459049_0	518766.Rmar_2586	2.654e-148	482.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
GNS2_k127_1459049_1	1238182.C882_0426	7.295e-123	400.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,2JQ4F@204441|Rhodospirillales	204441|Rhodospirillales	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
GNS2_k127_1459049_4	1254432.SCE1572_30715	8.257e-26	110.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GNS2_k127_1459784_5	743719.PaelaDRAFT_4351	2.409e-41	164.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
GNS2_k127_1459784_4	390989.JOEG01000017_gene6236	9.85e-71	254.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4DDCM@85008|Micromonosporales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GNS2_k127_1459784_1	1499967.BAYZ01000036_gene2415	1.171e-186	596.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
GNS2_k127_1459784_3	1123508.JH636451_gene5944	5.811e-88	305.0	COG3239@1|root,COG3239@2|Bacteria,2J09R@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GNS2_k127_1459784_2	1267534.KB906758_gene2269	2.376e-95	334.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GNS2_k127_1459784_9	1196324.A374_16123	5.575e-10	69.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GNS2_k127_1459784_10	1157490.EL26_15165	2.161e-08	57.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,279YC@186823|Alicyclobacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	ydaF	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GNS2_k127_1459784_8	1121033.AUCF01000009_gene1120	2.375e-27	128.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,2UIK4@28211|Alphaproteobacteria,2JUUA@204441|Rhodospirillales	204441|Rhodospirillales	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
GNS2_k127_1459784_0	518766.Rmar_2590	4.672e-192	612.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
GNS2_k127_1459784_6	1304865.JAGF01000001_gene2441	6.756e-40	149.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
GNS2_k127_1474160_1	469383.Cwoe_4474	4.967e-37	145.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	sseA2	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GNS2_k127_1474160_2	1297742.A176_07149	3.096e-30	122.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1474160_0	661478.OP10G_1986	5.122e-131	440.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3,Beta-lactamase
GNS2_k127_1506124_4	1122611.KB903945_gene1398	4.146e-25	122.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4EFZB@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GNS2_k127_1506124_3	713587.THITH_04115	4.511e-59	233.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
GNS2_k127_1506124_0	215803.DB30_1185	2.151e-122	403.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GNS2_k127_1506124_2	1089550.ATTH01000001_gene2559	7.604e-93	313.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,1FJRI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
GNS2_k127_1506124_1	1173026.Glo7428_3072	6.084e-101	340.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0P4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
GNS2_k127_1506124_5	1173025.GEI7407_2987	2.023e-17	95.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3447@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
GNS2_k127_1513686_6	290397.Adeh_3502	0.0003352	48.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GNS2_k127_1513686_1	1499967.BAYZ01000159_gene502	4.708e-54	208.0	COG2203@1|root,COG2208@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3437@2|Bacteria,2NQW9@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3,4.6.1.1	ko:K01079,ko:K01768,ko:K07315	ko00230,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02025,ko04113,ko04213,map00230,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02025,map04113,map04213	M00020,M00695	R00089,R00434,R00582	RC00017,RC00295	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HATPase_c_2,Response_reg,SSF,SpoIIE
GNS2_k127_1513686_5	204669.Acid345_2199	2.447e-30	132.0	COG1725@1|root,COG1725@2|Bacteria,3Y8PU@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GNS2_k127_1513686_4	670487.Ocepr_0569	1.241e-30	136.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GNS2_k127_1513686_0	497965.Cyan7822_4459	1.316e-233	745.0	COG0531@1|root,COG0531@2|Bacteria,1G1I6@1117|Cyanobacteria,3KH44@43988|Cyanothece	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1513686_3	448385.sce6679	8.867e-33	148.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GNS2_k127_1513686_2	1382306.JNIM01000001_gene3896	8.903e-45	168.0	COG2945@1|root,COG2945@2|Bacteria,2G9MQ@200795|Chloroflexi	200795|Chloroflexi	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GNS2_k127_1519849_0	234267.Acid_5688	5.714e-208	669.0	COG1009@1|root,COG1009@2|Bacteria,3Y2VS@57723|Acidobacteria	2|Bacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GNS2_k127_1519849_1	1131269.AQVV01000018_gene1926	1.354e-168	546.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GNS2_k127_1519849_6	1051646.VITU9109_26155	1.452e-31	138.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales	135623|Vibrionales	S	permease	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GNS2_k127_1519849_11	1265505.ATUG01000001_gene3275	4.456e-05	48.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42VWC@68525|delta/epsilon subdivisions,2WS5S@28221|Deltaproteobacteria,2MKV4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
GNS2_k127_1519849_4	1191523.MROS_0276	1.466e-51	199.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GNS2_k127_1519849_8	404589.Anae109_4486	3.319e-19	89.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	iHN637.CLJU_RS01165	ATP-synt_C
GNS2_k127_1519849_5	404589.Anae109_4485	2.831e-37	149.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GNS2_k127_1519849_10	1246626.BleG1_3504	1.141e-06	55.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1519849_9	653733.Selin_1392	1.218e-18	92.0	2EQS7@1|root,33IC3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1519849_3	316067.Geob_2080	3.502e-83	311.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria,43SW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GNS2_k127_1519849_2	247490.KSU1_D0862	3.147e-117	395.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GNS2_k127_1519849_7	1437425.CSEC_0822	8.914e-20	103.0	COG1538@1|root,COG1538@2|Bacteria,2JGM1@204428|Chlamydiae	204428|Chlamydiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GNS2_k127_1524046_2	880073.Calab_1640	8.136e-48	189.0	COG2067@1|root,COG2067@2|Bacteria,2NPN1@2323|unclassified Bacteria	2|Bacteria	I	Membrane protein involved in aromatic hydrocarbon degradation	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
GNS2_k127_1524046_3	945713.IALB_1544	1.41e-43	183.0	COG3240@1|root,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	-	ko:K15349	ko05132,map05132	-	-	-	ko00000,ko00001	-	-	-	Lipase_GDSL,Lipase_GDSL_2
GNS2_k127_1524046_7	864069.MicloDRAFT_00052050	2.978e-05	52.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2TVRG@28211|Alphaproteobacteria,1JU5T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GNS2_k127_1524046_6	926550.CLDAP_20580	1.816e-24	115.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GNS2_k127_1524046_5	1410619.SRDD_06130	5.076e-28	119.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,403F6@613|Serratia	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
GNS2_k127_1524046_1	314230.DSM3645_05435	8.893e-130	461.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
GNS2_k127_1524046_0	316274.Haur_4105	0.0	1208.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GNS2_k127_1524046_4	1068980.ARVW01000001_gene6072	3.763e-36	141.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DZG7@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
GNS2_k127_1531726_1	1267535.KB906767_gene3095	2.495e-71	250.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria,2JI0C@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GNS2_k127_1531726_0	913865.DOT_2186	1.425e-110	365.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,2608G@186807|Peptococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GNS2_k127_1531726_2	926550.CLDAP_16590	4.298e-39	147.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1533448_0	316067.Geob_1654	1.05e-133	432.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,42QH0@68525|delta/epsilon subdivisions,2WJY7@28221|Deltaproteobacteria,43UNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
GNS2_k127_1533448_2	1122223.KB890687_gene2691	1.884e-42	161.0	COG2318@1|root,COG2318@2|Bacteria,1WNBD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_1533448_3	682795.AciX8_2132	1.963e-06	51.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
GNS2_k127_1533448_1	330214.NIDE0059	6.254e-78	269.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
GNS2_k127_1552178_5	1125863.JAFN01000001_gene3409	6.233e-07	61.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
GNS2_k127_1552178_1	234267.Acid_6470	7.54e-120	419.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
GNS2_k127_1552178_0	1382359.JIAL01000001_gene2740	0.0	1082.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GNS2_k127_1552178_4	1487953.JMKF01000006_gene5751	1.835e-20	108.0	COG2304@1|root,COG2931@1|root,COG4932@1|root,COG5276@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Cadherin,Calx-beta,DUF4347,HemolysinCabind,Lectin_C
GNS2_k127_1552178_3	1232683.ADIMK_3660	3.499e-66	250.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,466E9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
GNS2_k127_1552178_2	204669.Acid345_3567	1.389e-112	377.0	COG4591@1|root,COG4591@2|Bacteria,3Y3BU@57723|Acidobacteria,2JIC6@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
GNS2_k127_157447_1	290397.Adeh_4354	5.908e-55	199.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GNS2_k127_157447_0	1125863.JAFN01000001_gene2683	1.296e-94	319.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GNS2_k127_1578943_2	204669.Acid345_1392	2.135e-87	292.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GNS2_k127_1578943_0	204669.Acid345_1391	2.481e-175	556.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GNS2_k127_1578943_1	1232410.KI421416_gene2594	7.144e-139	451.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43RZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GNS2_k127_1580770_7	1198114.AciX9_3665	1.322e-05	57.0	28MS6@1|root,2ZB0K@2|Bacteria,3Y38I@57723|Acidobacteria,2JHU5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1580770_2	398767.Glov_1981	8.947e-58	210.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,43SVS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GNS2_k127_1580770_0	330214.NIDE2440	0.0	1376.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,3J0HX@40117|Nitrospirae	40117|Nitrospirae	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
GNS2_k127_1580770_3	391625.PPSIR1_33596	5.98e-56	219.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2WWZ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GNS2_k127_1580770_4	1535422.ND16A_1058	7.781e-37	147.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria,1S7BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GNS2_k127_1580770_5	444158.MmarC6_0920	2.713e-16	88.0	arCOG02879@1|root,arCOG02879@2157|Archaea,2XYKT@28890|Euryarchaeota,23R3A@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
GNS2_k127_1580770_1	1379698.RBG1_1C00001G0629	2.169e-216	697.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
GNS2_k127_1580770_6	278963.ATWD01000001_gene3347	1.198e-11	75.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
GNS2_k127_1619674_2	1122179.KB890422_gene2260	1.476e-08	65.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_M6
GNS2_k127_1619674_1	443143.GM18_0292	1.705e-81	284.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GNS2_k127_1619674_0	748280.NH8B_2766	2.508e-257	815.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
GNS2_k127_1687734_0	269799.Gmet_0022	2.528e-197	634.0	COG1916@1|root,COG1916@2|Bacteria,1R5SH@1224|Proteobacteria,42Q6N@68525|delta/epsilon subdivisions,2WKNS@28221|Deltaproteobacteria,43U80@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1687734_3	1379698.RBG1_1C00001G0511	1.372e-68	241.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GNS2_k127_1687734_1	1121430.JMLG01000002_gene1080	7.863e-105	347.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GNS2_k127_1687734_4	1210884.HG799464_gene11117	3.135e-44	164.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
GNS2_k127_1687734_2	1122915.AUGY01000011_gene4004	7.164e-78	278.0	COG1132@1|root,COG1132@2|Bacteria,1TUQD@1239|Firmicutes,4HTPJ@91061|Bacilli,26U3G@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,cNMP_binding
GNS2_k127_1727279_0	518766.Rmar_1486	8.61e-261	818.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GNS2_k127_1727279_5	314285.KT71_02967	3.628e-14	81.0	2EHU8@1|root,33BJW@2|Bacteria,1NIG4@1224|Proteobacteria,1SJ06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1727279_1	234267.Acid_7147	4.419e-137	440.0	COG0714@1|root,COG0714@2|Bacteria,3Y6Z3@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GNS2_k127_1727279_2	1183438.GKIL_0023	1.629e-136	456.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
GNS2_k127_1727279_6	65497.JODV01000006_gene859	8.73e-13	79.0	COG2981@1|root,COG2981@2|Bacteria,2GJZ4@201174|Actinobacteria,4E0AM@85010|Pseudonocardiales	201174|Actinobacteria	E	protein involved in cysteine biosynthesis	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
GNS2_k127_1727279_3	357808.RoseRS_4085	1.591e-79	274.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_1727279_4	357808.RoseRS_4086	5.207e-40	156.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_174790_9	269796.Rru_A0737	1.402e-16	81.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2JSB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GNS2_k127_174790_8	1550091.JROE01000006_gene2512	6.033e-23	111.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
GNS2_k127_174790_7	1267535.KB906767_gene1043	8.148e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_174790_11	269799.Gmet_1229	7.473e-11	69.0	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,42V4W@68525|delta/epsilon subdivisions,2WR6H@28221|Deltaproteobacteria,43V3T@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GNS2_k127_174790_10	1191523.MROS_2413	1.206e-11	74.0	2CG1Y@1|root,2Z9QX@2|Bacteria	2|Bacteria	S	COG NOG19146 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
GNS2_k127_174790_5	1144275.COCOR_02486	2.91e-87	297.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
GNS2_k127_174790_3	234267.Acid_2875	2.76e-139	490.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GNS2_k127_174790_0	635013.TherJR_2732	0.0	1042.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GNS2_k127_174790_13	56107.Cylst_4248	0.0003655	51.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1HIQE@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GNS2_k127_174790_4	1125863.JAFN01000001_gene2734	8.935e-126	417.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
GNS2_k127_174790_1	1267535.KB906767_gene2550	6.67e-248	779.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GNS2_k127_174790_2	635013.TherJR_0848	5.297e-173	591.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GNS2_k127_174790_6	760568.Desku_0006	3.884e-70	244.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GNS2_k127_1774587_5	671143.DAMO_2311	4.548e-66	234.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
GNS2_k127_1774587_1	861299.J421_2707	5.823e-180	585.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GNS2_k127_1774587_0	234267.Acid_5694	8.995e-181	610.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_1774587_6	1499967.BAYZ01000121_gene3405	3.745e-44	178.0	COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide export protein	-	-	-	ko:K01991,ko:K20988	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GNS2_k127_1774587_2	1313172.YM304_32850	1.769e-134	462.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria	201174|Actinobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GNS2_k127_1774587_3	1396141.BATP01000056_gene3203	5.998e-76	283.0	COG0438@1|root,COG0438@2|Bacteria,46VRS@74201|Verrucomicrobia,2IW1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
GNS2_k127_1774587_4	1125973.JNLC01000018_gene2130	3.167e-74	267.0	COG0265@1|root,COG0265@2|Bacteria,1R6VW@1224|Proteobacteria,2UNAP@28211|Alphaproteobacteria,3K1U9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1774587_8	404380.Gbem_1587	3.902e-37	145.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GNS2_k127_1774587_7	1125863.JAFN01000001_gene3582	3.004e-39	162.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GNS2_k127_1774587_9	1033743.CAES01000096_gene2722	2.078e-36	156.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,271RY@186822|Paenibacillaceae	91061|Bacilli	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GNS2_k127_1774587_10	1121033.AUCF01000011_gene1857	8.298e-19	85.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2JQNS@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GNS2_k127_184108_2	861299.J421_4062	7.05e-61	227.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_184108_1	1278073.MYSTI_02341	1.309e-64	240.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GNS2_k127_184108_8	638303.Thal_0359	2.029e-11	73.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ1	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GNS2_k127_184108_3	1121920.AUAU01000023_gene2406	1.165e-39	168.0	2DMMW@1|root,32SIJ@2|Bacteria,3Y8YH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_184108_6	1047013.AQSP01000072_gene985	2.068e-26	119.0	COG1426@1|root,COG1426@2|Bacteria,2NQ7E@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GNS2_k127_184108_7	269799.Gmet_0176	9.854e-19	96.0	2DE9Y@1|root,2ZM4N@2|Bacteria,1Q17X@1224|Proteobacteria,43756@68525|delta/epsilon subdivisions,2X21C@28221|Deltaproteobacteria,43SFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_184108_0	378806.STAUR_5253	3.188e-75	271.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
GNS2_k127_184108_5	404589.Anae109_1348	5.4e-29	126.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
GNS2_k127_184108_9	234267.Acid_2564	1.155e-07	56.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_184108_4	290397.Adeh_0651	1.324e-34	144.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
GNS2_k127_1872130_0	760568.Desku_1847	9.869e-108	360.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,2603K@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GNS2_k127_1872130_3	395965.Msil_2318	2.052e-28	123.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,3NA0H@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	3-dehydroquinate synthase	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GNS2_k127_1872130_1	1047013.AQSP01000033_gene1389	1.009e-72	252.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GNS2_k127_1872130_2	234267.Acid_1082	3.117e-40	164.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria	57723|Acidobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
GNS2_k127_1872130_4	33876.JNXY01000024_gene5028	1.043e-09	67.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4D8U9@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_192168_2	383372.Rcas_1489	1.791e-06	50.0	COG0438@1|root,COG0438@2|Bacteria,2GB6D@200795|Chloroflexi,3753H@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GNS2_k127_192168_0	326427.Cagg_2212	6.462e-52	199.0	COG0438@1|root,COG0438@2|Bacteria,2GABK@200795|Chloroflexi,374ZN@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_192168_1	1521187.JPIM01000007_gene1357	4.168e-17	86.0	COG0438@1|root,COG0438@2|Bacteria,2GABS@200795|Chloroflexi,3752C@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_1944493_9	383372.Rcas_2343	1.197e-32	147.0	COG0500@1|root,COG2226@2|Bacteria,2GACE@200795|Chloroflexi,37588@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_1944493_2	1128421.JAGA01000002_gene389	4.621e-74	278.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_1944493_10	1142394.PSMK_18180	7.086e-30	134.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	walM	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_1944493_13	358681.BBR47_16620	6.272e-14	85.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,4ITCP@91061|Bacilli,277C7@186822|Paenibacillaceae	91061|Bacilli	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_1944493_11	62928.azo3578	3.588e-23	113.0	COG0438@1|root,COG0438@2|Bacteria,1QIXJ@1224|Proteobacteria,2VKFD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_1944493_5	880073.Calab_2316	6.285e-47	191.0	COG0726@1|root,COG0726@2|Bacteria,2NRRE@2323|unclassified Bacteria	2|Bacteria	G	polysaccharide deacetylase	walW	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1944493_12	671143.DAMO_0253	5.8e-16	89.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
GNS2_k127_1944493_6	886293.Sinac_0168	3.264e-46	177.0	COG2032@1|root,COG2032@2|Bacteria,2J01T@203682|Planctomycetes	203682|Planctomycetes	P	COG2032 Cu Zn superoxide dismutase	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
GNS2_k127_1944493_4	880073.Calab_1364	9.311e-51	198.0	COG2244@1|root,COG2244@2|Bacteria,2NQ4Y@2323|unclassified Bacteria	2|Bacteria	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
GNS2_k127_1944493_0	886293.Sinac_6462	8.816e-134	438.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GNS2_k127_1944493_3	1127695.HMPREF9163_01459	1.008e-65	254.0	COG1083@1|root,COG3980@1|root,COG1083@2|Bacteria,COG3980@2|Bacteria,1UZUM@1239|Firmicutes	1239|Firmicutes	M	CMP-N-acetylneuraminic acid synthetase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3,DUF354,Glyco_tran_28_C
GNS2_k127_1944493_1	593750.Metfor_1307	3.688e-84	299.0	COG2089@1|root,arCOG01050@2157|Archaea,2XTT7@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM N-acetylneuraminic acid synthase	neuB	-	2.5.1.101,2.5.1.56,2.5.1.97	ko:K01654,ko:K15898,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
GNS2_k127_1944493_7	477974.Daud_1771	1.564e-44	181.0	COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,24B0X@186801|Clostridia,264GQ@186807|Peptococcaceae	186801|Clostridia	M	Cytidylyltransferase	spsF	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
GNS2_k127_1944493_8	189425.PGRAT_01340	3.658e-37	151.0	COG1861@1|root,COG2089@1|root,COG1861@2|Bacteria,COG2089@2|Bacteria,1VSGK@1239|Firmicutes,4HV78@91061|Bacilli,270KB@186822|Paenibacillaceae	91061|Bacilli	M	NeuB family	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3,NeuB
GNS2_k127_1958173_1	204669.Acid345_4042	2.577e-131	439.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GNS2_k127_1958173_2	161156.JQKW01000008_gene533	7.794e-69	241.0	COG1611@1|root,COG1611@2|Bacteria,2GH3X@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GNS2_k127_1958173_4	645465.ACUR01000255_gene2065	2.334e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_1958173_7	751945.Theos_0377	3.869e-05	55.0	2E5K6@1|root,330BD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_1958173_0	1267535.KB906767_gene1007	2.689e-141	464.0	2CI5Q@1|root,2Z7M7@2|Bacteria,3Y3IR@57723|Acidobacteria,2JHQP@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
GNS2_k127_1958173_3	1267535.KB906767_gene623	4.003e-44	181.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GNS2_k127_1958173_5	1340493.JNIF01000003_gene2460	2.245e-11	74.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GNS2_k127_2010194_14	1254432.SCE1572_51405	0.0001427	48.0	COG0500@1|root,COG2226@2|Bacteria,1QDTU@1224|Proteobacteria,439CY@68525|delta/epsilon subdivisions,2X4MH@28221|Deltaproteobacteria,2YZ94@29|Myxococcales	28221|Deltaproteobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_2010194_0	1168034.FH5T_20565	0.0	1074.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GNS2_k127_2010194_8	319003.Bra1253DRAFT_07429	5.631e-46	174.0	COG2020@1|root,COG2020@2|Bacteria,1RDC4@1224|Proteobacteria,2TUXA@28211|Alphaproteobacteria,3JU1Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GNS2_k127_2010194_11	1403819.BATR01000065_gene1929	2.177e-15	79.0	2CX21@1|root,32T0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2010194_7	379066.GAU_3720	4.663e-48	181.0	28KW4@1|root,2ZACH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2010194_6	502025.Hoch_5093	2.504e-55	203.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GNS2_k127_2010194_1	1192034.CAP_2782	4.284e-155	506.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2YYUX@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
GNS2_k127_2010194_9	326427.Cagg_3173	5.138e-33	146.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi,375VA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GNS2_k127_2010194_13	1089547.KB913013_gene2263	1.801e-05	59.0	2C08E@1|root,2ZBCG@2|Bacteria,4NGBR@976|Bacteroidetes,47MV3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2010194_4	1089547.KB913013_gene2262	1.767e-119	411.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
GNS2_k127_2010194_3	926549.KI421517_gene511	2.255e-131	461.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47N91@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GNS2_k127_2010194_2	204669.Acid345_3936	2.792e-133	467.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_2010194_12	644282.Deba_2164	6.433e-08	64.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181	ko:K00568,ko:K18827	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781,R10657,R10658	RC00002,RC00003,RC00078,RC00392,RC01895,RC03220	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Condensation,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding,TPR_1,TPR_16,TPR_8
GNS2_k127_2010194_5	596151.DesfrDRAFT_2463	1.14e-90	311.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria,2M9ER@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
GNS2_k127_2010194_10	710421.Mycch_4405	1.232e-24	115.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria,234UG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
GNS2_k127_2013689_5	1128421.JAGA01000002_gene1351	2.522e-38	154.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_2013689_3	1313301.AUGC01000001_gene1534	5.064e-56	205.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GNS2_k127_2013689_4	926550.CLDAP_02060	1.473e-51	210.0	COG1807@1|root,COG1807@2|Bacteria,2G8SF@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_2013689_1	197221.22295068	3.402e-103	362.0	COG0399@1|root,COG0399@2|Bacteria,1G3C6@1117|Cyanobacteria	1117|Cyanobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GNS2_k127_2013689_0	926550.CLDAP_39770	4.615e-135	451.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GNS2_k127_2013689_2	316274.Haur_3900	1.433e-100	336.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_2013689_6	1384056.N787_03970	7.592e-19	101.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,1PDH2@1224|Proteobacteria,1RW0I@1236|Gammaproteobacteria,1XBIQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_2082750_3	404589.Anae109_0210	1.794e-67	237.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2Z2XX@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_2082750_5	253839.SSNG_01026	1.016e-07	65.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	ko:K16428,ko:K16429	ko01055,map01055	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
GNS2_k127_2082750_1	696281.Desru_1544	3.448e-102	347.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GNS2_k127_2082750_0	1262449.CP6013_2848	1.586e-102	342.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,24A20@186801|Clostridia,36G4Y@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_2082750_2	1453503.AU05_09455	2.416e-80	276.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1YKRY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_2082750_4	136993.KB900626_gene3459	1.776e-10	68.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,36ZEE@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_2095361_5	243231.GSU0538	4.274e-42	178.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,43UXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GNS2_k127_2095361_0	1499967.BAYZ01000026_gene1569	2.474e-303	941.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GNS2_k127_2095361_1	886293.Sinac_1500	7.99e-179	591.0	COG1297@1|root,COG1297@2|Bacteria,2IYGI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GNS2_k127_2095361_4	1121920.AUAU01000022_gene2463	2.967e-75	265.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1099	AAA_28,Thymidylate_kin
GNS2_k127_2095361_7	234267.Acid_0082	1.635e-11	74.0	2FE51@1|root,3464Y@2|Bacteria,3Y8E0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2095361_2	502025.Hoch_0018	2.304e-133	439.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_2095361_8	273068.TTE2583	9.202e-05	45.0	2E3GV@1|root,32YFJ@2|Bacteria,1VGVF@1239|Firmicutes,24S3F@186801|Clostridia,42H7R@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2095361_3	204669.Acid345_1733	2.691e-79	292.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	2|Bacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GNS2_k127_2111198_0	518766.Rmar_0910	4.148e-273	871.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes	976|Bacteroidetes	T	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
GNS2_k127_2111198_1	1131269.AQVV01000004_gene642	2.315e-70	246.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GNS2_k127_2126764_8	526227.Mesil_0281	1.221e-39	158.0	COG0604@1|root,COG0604@2|Bacteria,1WIQ2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_2126764_7	530564.Psta_3139	5.853e-53	197.0	COG0235@1|root,COG0235@2|Bacteria,2J2P1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
GNS2_k127_2126764_5	1173264.KI913949_gene37	1.137e-72	251.0	COG1791@1|root,COG1791@2|Bacteria,1G274@1117|Cyanobacteria	1117|Cyanobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
GNS2_k127_2126764_6	251229.Chro_0354	8.949e-61	223.0	COG4229@1|root,COG4229@2|Bacteria,1G59P@1117|Cyanobacteria	1117|Cyanobacteria	E	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
GNS2_k127_2126764_3	391625.PPSIR1_30230	2.652e-122	413.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,42R72@68525|delta/epsilon subdivisions,2WMSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GNS2_k127_2126764_9	471853.Bcav_3749	2.477e-25	119.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GNS2_k127_2126764_2	448385.sce7073	8.284e-136	449.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria,2Z2VK@29|Myxococcales	28221|Deltaproteobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
GNS2_k127_2126764_0	84531.JMTZ01000136_gene2443	1.537e-288	899.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales	1236|Gammaproteobacteria	O	peptidase	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
GNS2_k127_2126764_1	35754.JNYJ01000001_gene7213	5.18e-154	494.0	COG1940@1|root,COG1940@2|Bacteria,2IB2E@201174|Actinobacteria,4D8WY@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	glcK	-	-	-	-	-	-	-	-	-	-	-	ROK
GNS2_k127_2126764_4	306281.AJLK01000058_gene1083	3.599e-91	304.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1JKC1@1189|Stigonemataceae	1117|Cyanobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
GNS2_k127_2160977_1	1156919.QWC_15554	3.122e-69	245.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,3T2WT@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the PdxA family	pdxA2	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GNS2_k127_2160977_0	1210884.HG799465_gene12267	3.121e-80	301.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
GNS2_k127_2160977_2	317619.ANKN01000230_gene252	1.094e-33	151.0	COG0739@1|root,COG0823@1|root,COG1520@1|root,COG2931@1|root,COG3386@1|root,COG0739@2|Bacteria,COG0823@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,1GJ06@1117|Cyanobacteria,1MN0C@1212|Prochloraceae	1117|Cyanobacteria	Q	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4214
GNS2_k127_2164678_4	1121468.AUBR01000020_gene2853	1.911e-45	166.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
GNS2_k127_2164678_0	479434.Sthe_1801	4.87e-169	546.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_2164678_6	313628.LNTAR_17943	6.25e-13	80.0	28N9P@1|root,2ZBDN@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GNS2_k127_2164678_3	671143.DAMO_2057	1.051e-85	297.0	COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
GNS2_k127_2164678_2	861299.J421_2858	8.963e-93	317.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
GNS2_k127_2164678_1	1499967.BAYZ01000117_gene3327	9.455e-116	392.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
GNS2_k127_2170362_0	1047013.AQSP01000132_gene1707	4.764e-131	442.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
GNS2_k127_2170362_1	1047013.AQSP01000132_gene1706	2.947e-12	69.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GNS2_k127_2188559_8	1254432.SCE1572_04620	1.022e-25	110.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,43A75@68525|delta/epsilon subdivisions,2X9W3@28221|Deltaproteobacteria,2Z1PF@29|Myxococcales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GNS2_k127_2188559_3	398767.Glov_1866	4.654e-64	229.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GNS2_k127_2188559_2	56780.SYN_02850	1.864e-105	360.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MQCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GNS2_k127_2188559_5	398767.Glov_2305	2.772e-48	185.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GNS2_k127_2188559_6	583355.Caka_1220	2.828e-35	154.0	COG0457@1|root,COG3379@1|root,COG3551@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,COG3551@2|Bacteria,46URB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GNS2_k127_2188559_7	1121468.AUBR01000018_gene2719	6.68e-30	121.0	COG0073@1|root,COG0073@2|Bacteria,1V6N9@1239|Firmicutes,24JJZ@186801|Clostridia,42GXA@68295|Thermoanaerobacterales	186801|Clostridia	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
GNS2_k127_2188559_4	373903.Hore_09350	2.229e-60	214.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
GNS2_k127_2188559_1	338963.Pcar_1615	1.19e-112	386.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GNS2_k127_2188559_0	1121423.JONT01000013_gene342	8.751e-144	486.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GNS2_k127_2188749_2	234267.Acid_5771	3.997e-23	103.0	COG2010@1|root,COG2010@2|Bacteria,3Y5Q0@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GNS2_k127_2188749_3	573061.Clocel_3502	5.402e-17	96.0	COG0502@1|root,COG0502@2|Bacteria,1VF49@1239|Firmicutes,249FT@186801|Clostridia,36GY7@31979|Clostridiaceae	186801|Clostridia	H	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GNS2_k127_2188749_0	1121920.AUAU01000017_gene1239	7.504e-222	703.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
GNS2_k127_2188749_1	1232410.KI421413_gene725	5.543e-50	183.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,43UMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GNS2_k127_2188941_6	1453501.JELR01000001_gene2492	2.671e-14	77.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,4687T@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GNS2_k127_2188941_4	1382359.JIAL01000001_gene2644	9.722e-75	259.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GNS2_k127_2188941_9	219305.MCAG_04128	0.0002336	53.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D9MF@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GNS2_k127_2188941_5	290397.Adeh_0104	4.804e-39	159.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
GNS2_k127_2188941_7	378806.STAUR_0711	9.37e-13	73.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
GNS2_k127_2188941_8	1254432.SCE1572_27715	1.496e-05	56.0	2DRPS@1|root,33CHR@2|Bacteria,1NKKC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2188941_1	296591.Bpro_4702	2.408e-172	571.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VK5V@28216|Betaproteobacteria,4AAPR@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GNS2_k127_2188941_2	296591.Bpro_4700	2.059e-127	417.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4AD0R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
GNS2_k127_2188941_0	1121904.ARBP01000012_gene1211	1.034e-178	573.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GNS2_k127_2188941_3	861299.J421_0692	1.02e-98	325.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GNS2_k127_220340_0	1047013.AQSP01000131_gene1841	6.406e-121	419.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_2215752_1	1380394.JADL01000017_gene493	6.929e-72	252.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria,2JQ2G@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD binding domain	-	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GNS2_k127_2215752_0	391625.PPSIR1_10520	1.007e-98	331.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
GNS2_k127_2215752_2	1300345.LF41_311	1.003e-37	149.0	2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,1SBBP@1236|Gammaproteobacteria,1X8WF@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_230872_1	909663.KI867150_gene1676	7.962e-70	242.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GNS2_k127_230872_0	443144.GM21_3060	3.418e-77	269.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GNS2_k127_2344768_0	234267.Acid_5676	4.219e-268	856.0	COG0515@1|root,COG1262@1|root,COG1506@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	1.14.99.50,2.7.11.1	ko:K01990,ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	M00254	R11013	RC03323,RC03324	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1	-	-	FGE-sulfatase,Peptidase_S15,Pkinase
GNS2_k127_2344768_1	263358.VAB18032_22370	4.026e-245	779.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria,4DC47@85008|Micromonosporales	201174|Actinobacteria	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GNS2_k127_2344768_2	477974.Daud_0168	1.653e-225	716.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
GNS2_k127_2344768_4	941449.dsx2_3175	1.01e-87	305.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GNS2_k127_2344768_3	243233.MCA0142	2.696e-100	355.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GNS2_k127_2359655_10	1304877.KI519399_gene3354	0.0008193	51.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,3JRJ0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_2359655_0	404589.Anae109_1755	6.975e-148	482.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GNS2_k127_2359655_7	1499680.CCFE01000033_gene3976	5.858e-44	162.0	COG0073@1|root,COG0073@2|Bacteria,1VGDC@1239|Firmicutes	1239|Firmicutes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
GNS2_k127_2359655_3	1499967.BAYZ01000038_gene2273	4.62e-95	332.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GNS2_k127_2359655_4	1047013.AQSP01000140_gene2463	6.187e-91	328.0	COG0438@1|root,COG0438@2|Bacteria,2NQE7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GNS2_k127_2359655_5	1047013.AQSP01000140_gene2462	5.409e-90	325.0	COG0438@1|root,COG0438@2|Bacteria,2NQE7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GNS2_k127_2359655_2	1047013.AQSP01000140_gene2461	7.108e-97	337.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GNS2_k127_2359655_1	1047013.AQSP01000140_gene2461	4.276e-133	437.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GNS2_k127_2359655_9	1499967.BAYZ01000193_gene3920	9.327e-06	55.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.197,2.1.1.222,2.1.1.64	ko:K00568,ko:K02169	ko00130,ko00780,ko01100,ko01110,map00130,map00780,map01100,map01110	M00117,M00572	R04988,R05614,R08769,R08781,R09543	RC00003,RC00392,RC00460,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_8
GNS2_k127_2359655_6	1379698.RBG1_1C00001G1327	1.147e-87	304.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
GNS2_k127_2359655_8	1340493.JNIF01000003_gene4350	6.312e-33	131.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
GNS2_k127_2362820_3	1267533.KB906735_gene4889	7.405e-41	165.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,Glyoxalase,HAMP,Response_reg,SpoIIE
GNS2_k127_2362820_2	1267534.KB906755_gene4787	4.844e-77	273.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
GNS2_k127_2362820_0	204669.Acid345_1576	4.145e-228	717.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GNS2_k127_2362820_6	1382359.JIAL01000001_gene1457	2.036e-17	98.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GNS2_k127_2362820_7	204669.Acid345_1577	1.972e-07	64.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GNS2_k127_2362820_4	1267534.KB906756_gene157	2.312e-39	153.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GNS2_k127_2362820_5	404380.Gbem_1286	7.932e-31	132.0	COG2165@1|root,COG2165@2|Bacteria,1R02Y@1224|Proteobacteria,43CQ3@68525|delta/epsilon subdivisions,2X7XC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Pfam:N_methyl_2	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
GNS2_k127_2362820_9	682795.AciX8_0669	0.000148	51.0	2C8FF@1|root,333TN@2|Bacteria,3Y5GA@57723|Acidobacteria,2JJYB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2362820_1	1047013.AQSP01000036_gene1385	2.358e-82	302.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
GNS2_k127_2364810_0	1382359.JIAL01000001_gene480	6.907e-107	363.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
GNS2_k127_2364810_2	404589.Anae109_0975	1.364e-16	88.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WSSJ@28221|Deltaproteobacteria,2YVJB@29|Myxococcales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
GNS2_k127_2364810_1	357808.RoseRS_2164	3.04e-76	269.0	COG1752@1|root,COG1752@2|Bacteria,2G7GM@200795|Chloroflexi,374ZF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
GNS2_k127_2378664_5	1449347.JQLN01000007_gene1106	3.893e-23	111.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria,2M62J@2063|Kitasatospora	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
GNS2_k127_2378664_0	479434.Sthe_3373	2.828e-88	314.0	COG0654@1|root,COG0654@2|Bacteria,2G66I@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GNS2_k127_2378664_1	926566.Terro_4112	4.728e-62	222.0	COG1028@1|root,COG1028@2|Bacteria,3Y3FQ@57723|Acidobacteria,2JHPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GNS2_k127_2378664_2	457398.HMPREF0326_00564	3.16e-57	212.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GNS2_k127_2378664_3	243231.GSU2230	4.377e-45	179.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43UA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GNS2_k127_2378664_4	234267.Acid_0132	2.296e-26	113.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
GNS2_k127_2378664_6	1121875.KB907549_gene1914	1.689e-08	62.0	COG0657@1|root,COG0657@2|Bacteria,4NUK2@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GNS2_k127_2378664_7	637389.Acaty_c0101	1.351e-06	52.0	COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,PriCT_2,Toprim_2
GNS2_k127_2413159_4	1382359.JIAL01000001_gene2414	2.032e-35	137.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria,2JJRG@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
GNS2_k127_2413159_2	204669.Acid345_3656	9.538e-139	451.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GNS2_k127_2413159_1	1192034.CAP_5918	1.509e-140	462.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YY2T@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GNS2_k127_2413159_5	1167006.UWK_03185	3.158e-28	114.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GNS2_k127_2413159_0	926550.CLDAP_00560	0.0	1810.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
GNS2_k127_2413159_3	565033.GACE_1774	5.005e-52	195.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,24605@183980|Archaeoglobi	183980|Archaeoglobi	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GNS2_k127_2413159_6	1125863.JAFN01000001_gene1373	4.443e-07	56.0	2DD8H@1|root,2ZH1Z@2|Bacteria,1PBE0@1224|Proteobacteria,432B3@68525|delta/epsilon subdivisions,2WY4T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2428826_0	370438.PTH_2552	3.678e-60	213.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GNS2_k127_2428826_2	1173028.ANKO01000115_gene5831	6.259e-49	186.0	COG2971@1|root,COG2971@2|Bacteria,1G3SA@1117|Cyanobacteria,1H9RT@1150|Oscillatoriales	1117|Cyanobacteria	G	BadF BadG BcrA BcrD	-	-	2.7.1.59	ko:K00884,ko:K02616	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	BcrAD_BadFG
GNS2_k127_2428826_3	1304284.L21TH_1860	6.421e-44	178.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,24IMA@186801|Clostridia,36G15@31979|Clostridiaceae	186801|Clostridia	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GNS2_k127_2428826_1	378806.STAUR_1418	4.859e-49	194.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,42NH0@68525|delta/epsilon subdivisions,2WM42@28221|Deltaproteobacteria,2YX9A@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
GNS2_k127_2428826_4	867903.ThesuDRAFT_01972	1.015e-32	131.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
GNS2_k127_2443013_1	1382359.JIAL01000001_gene1357	8.464e-177	563.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
GNS2_k127_2443013_5	1214101.BN159_4248	1.422e-06	61.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PA14
GNS2_k127_2443013_3	644282.Deba_1874	1.203e-71	266.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GNS2_k127_2443013_2	330214.NIDE0493	7.335e-83	287.0	COG0176@1|root,COG0176@2|Bacteria,3J0YY@40117|Nitrospirae	40117|Nitrospirae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GNS2_k127_2443013_0	234267.Acid_1492	8.334e-247	772.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GNS2_k127_2443013_4	469383.Cwoe_5538	2.473e-57	206.0	COG0439@1|root,COG4770@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GNS2_k127_2529460_4	1206737.BAGF01000002_gene86	0.0006341	44.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4G1S8@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GNS2_k127_2529460_1	1192034.CAP_0946	3.083e-75	263.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GNS2_k127_2529460_0	1120983.KB894572_gene3010	3.346e-93	331.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_2529460_3	330779.Saci_1771	7.299e-10	72.0	COG3396@1|root,arCOG04786@2157|Archaea	2157|Archaea	S	Phenylacetate-CoA oxygenase	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GNS2_k127_2529460_2	1254432.SCE1572_12175	6.408e-58	216.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria,2YXDW@29|Myxococcales	28221|Deltaproteobacteria	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
GNS2_k127_253079_2	1007103.AFHW01000032_gene2246	1.056e-60	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GNS2_k127_253079_0	1158345.JNLL01000001_gene1282	2.216e-91	332.0	COG0260@1|root,COG0260@2|Bacteria,2G3TV@200783|Aquificae	200783|Aquificae	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GNS2_k127_253079_3	1009370.ALO_13025	3.187e-28	133.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4H3VY@909932|Negativicutes	909932|Negativicutes	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GNS2_k127_253079_1	1382306.JNIM01000001_gene346	4.228e-62	232.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GNS2_k127_2564191_1	234267.Acid_3485	8.88e-213	680.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GNS2_k127_2564191_0	234267.Acid_3484	6.855e-310	975.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GNS2_k127_2564191_3	706587.Desti_3511	7.281e-54	192.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GNS2_k127_2564191_2	1047013.AQSP01000140_gene2497	8.722e-119	405.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GNS2_k127_2576414_0	203124.Tery_0122	4.452e-128	448.0	COG0438@1|root,COG0457@1|root,COG4421@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG4421@2|Bacteria,1G2V7@1117|Cyanobacteria,1H9R5@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
GNS2_k127_2583783_1	713586.KB900536_gene2820	9.26e-130	425.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GNS2_k127_2583783_0	713586.KB900536_gene2819	7.95e-141	458.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
GNS2_k127_2583783_3	278963.ATWD01000001_gene4413	1.001e-87	318.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria,2JI1H@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GNS2_k127_2583783_2	234267.Acid_0057	6.922e-110	364.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GNS2_k127_2585612_6	161156.JQKW01000007_gene687	7.378e-36	141.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2GIQF@200940|Thermodesulfobacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GNS2_k127_2585612_1	671143.DAMO_0012	1.087e-241	758.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
GNS2_k127_2585612_2	1121939.L861_05420	2.236e-134	437.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales	135619|Oceanospirillales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GNS2_k127_2585612_0	1340493.JNIF01000003_gene3558	6.877e-286	893.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
GNS2_k127_2585612_3	448385.sce5671	1.39e-75	257.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GNS2_k127_2585612_5	1379698.RBG1_1C00001G0978	1.615e-47	181.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GNS2_k127_2585612_4	379066.GAU_0711	3.616e-64	228.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GNS2_k127_2648314_1	234831.PSM_A0515	2.339e-145	483.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	ERAP1-like C-terminal domain	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
GNS2_k127_2648314_4	240015.ACP_0299	5.381e-09	66.0	2A87I@1|root,30X8J@2|Bacteria,3Y4II@57723|Acidobacteria,2JJBN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbI
GNS2_k127_2648314_6	701347.Entcl_1320	0.0008026	49.0	COG4577@1|root,COG4577@2|Bacteria,1RCBV@1224|Proteobacteria,1S2HK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CQ	ethanolamine utilization protein	eutK	GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0050896	-	ko:K04025	-	-	-	-	ko00000	-	-	-	BMC,EutK_C
GNS2_k127_2648314_2	743718.Isova_2069	1.589e-22	99.0	COG3360@1|root,COG3360@2|Bacteria,2I0N2@201174|Actinobacteria,4F4X8@85017|Promicromonosporaceae	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GNS2_k127_2648314_0	472759.Nhal_1585	1.651e-215	685.0	COG0021@1|root,COG0176@1|root,COG0021@2|Bacteria,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1T2QT@1236|Gammaproteobacteria,1WWCJ@135613|Chromatiales	135613|Chromatiales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.1,2.2.1.2	ko:K00615,ko:K00616	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01827,R01830,R06590	RC00032,RC00226,RC00439,RC00571,RC00604,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N
GNS2_k127_2648314_3	195250.CM001776_gene3676	2.194e-11	72.0	COG2062@1|root,COG2062@2|Bacteria,1G6QD@1117|Cyanobacteria,1H1C1@1129|Synechococcus	1117|Cyanobacteria	T	Phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GNS2_k127_2648314_5	1150599.MPHLEI_12184	0.0004271	50.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,235BP@1762|Mycobacteriaceae	201174|Actinobacteria	S	CHAD	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
GNS2_k127_2654046_4	497964.CfE428DRAFT_2163	0.0006436	46.0	COG3664@1|root,COG3664@2|Bacteria,46UDS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_39
GNS2_k127_2654046_1	479434.Sthe_1778	9.703e-37	145.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	189775|Thermomicrobia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GNS2_k127_2654046_3	1396418.BATQ01000014_gene4363	4.636e-06	59.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia,2IUKV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2654046_0	744980.TRICHSKD4_3738	1.035e-57	218.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	MA20_30275	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GNS2_k127_2654046_2	765911.Thivi_2039	5.961e-07	62.0	COG3023@1|root,COG3023@2|Bacteria,1N0IM@1224|Proteobacteria,1S959@1236|Gammaproteobacteria,1WZ3E@135613|Chromatiales	135613|Chromatiales	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
GNS2_k127_269345_3	1267535.KB906767_gene1775	8.006e-89	297.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050,Stig1,ZU5
GNS2_k127_269345_8	1045855.DSC_06015	3.854e-41	167.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_269345_7	1282360.ABAC460_16060	2.236e-57	219.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2KFGH@204458|Caulobacterales	204458|Caulobacterales	T	TIGRFAM diguanylate cyclase	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
GNS2_k127_269345_6	204669.Acid345_3323	5.949e-83	295.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria,2JHTV@204432|Acidobacteriia	204432|Acidobacteriia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GNS2_k127_269345_2	234267.Acid_7937	4.353e-94	330.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_269345_1	1382359.JIAL01000001_gene1381	5.171e-95	329.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_269345_4	1047013.AQSP01000140_gene2536	8.306e-88	323.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_269345_9	1127673.GLIP_2482	7.665e-11	71.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM26,CBM_2,CBM_5_12_2,Cytochrome_CBB3,GSDH,He_PIG,PA14,PSCyt3,PSD2,PSD3,PSD4,PSD5
GNS2_k127_269345_5	671143.DAMO_1669	1.362e-83	302.0	COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5
GNS2_k127_269345_0	234267.Acid_3505	4.208e-121	398.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
GNS2_k127_2702039_1	485913.Krac_2434	3.666e-298	929.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GNS2_k127_2702039_5	1382306.JNIM01000001_gene1024	1.275e-97	355.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GNS2_k127_2702039_10	479434.Sthe_1762	8.684e-54	216.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2702039_2	215803.DB30_6830	1.368e-214	673.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GNS2_k127_2702039_3	1267535.KB906767_gene5052	8.39e-197	637.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
GNS2_k127_2702039_6	313624.NSP_14580	1.235e-87	310.0	COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria,1HIC7@1161|Nostocales	1117|Cyanobacteria	C	FAD binding domain	-	-	1.1.3.8,1.5.99.12	ko:K00103,ko:K00279	ko00053,ko00908,ko01100,map00053,map00908,map01100	M00129	R00647,R03184,R05708,R10053	RC00121,RC00195,RC00346,RC00869,RC01455	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,Cytokin-bind,FAD_binding_4
GNS2_k127_2702039_4	436229.JOEH01000014_gene6064	8.437e-143	467.0	COG4409@1|root,COG4409@2|Bacteria,2GN94@201174|Actinobacteria,2NEQG@228398|Streptacidiphilus	201174|Actinobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GNS2_k127_2702039_12	1379270.AUXF01000004_gene2933	4.456e-37	157.0	COG2755@1|root,COG2755@2|Bacteria,1ZU6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2702039_7	1304874.JAFY01000002_gene102	3.068e-86	312.0	COG2072@1|root,COG2072@2|Bacteria,3TCK9@508458|Synergistetes	508458|Synergistetes	P	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
GNS2_k127_2702039_8	324602.Caur_0649	1.408e-75	287.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
GNS2_k127_2702039_11	240292.Ava_4725	6.931e-49	201.0	COG2931@1|root,COG2931@2|Bacteria,1GIZT@1117|Cyanobacteria,1HMI7@1161|Nostocales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
GNS2_k127_2702039_9	204669.Acid345_1067	3.639e-72	259.0	COG0845@1|root,COG0845@2|Bacteria,3Y2NU@57723|Acidobacteria,2JHM0@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GNS2_k127_2702039_0	204669.Acid345_2817	0.0	1180.0	COG0841@1|root,COG0841@2|Bacteria,3Y2TW@57723|Acidobacteria,2JIKU@204432|Acidobacteriia	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GNS2_k127_2702039_13	1192034.CAP_7948	2.757e-17	95.0	COG1538@1|root,COG1538@2|Bacteria,1PDKT@1224|Proteobacteria,4398W@68525|delta/epsilon subdivisions,2X4G7@28221|Deltaproteobacteria,2YYYH@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GNS2_k127_2704368_2	215803.DB30_5015	1.036e-22	101.0	COG0526@1|root,COG0526@2|Bacteria,1NH1D@1224|Proteobacteria,42XJ2@68525|delta/epsilon subdivisions,2X5GC@28221|Deltaproteobacteria,2YUZX@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
GNS2_k127_2704368_3	246197.MXAN_6891	8.417e-11	63.0	COG0526@1|root,COG0526@2|Bacteria,1NH1D@1224|Proteobacteria,42XJ2@68525|delta/epsilon subdivisions,2X5GC@28221|Deltaproteobacteria,2YUZX@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
GNS2_k127_2704368_0	644966.Tmar_1638	3.606e-221	698.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GNS2_k127_2704368_1	1459636.NTE_01932	1.078e-67	256.0	COG2133@1|root,arCOG02796@2157|Archaea	1459636.NTE_01932|-	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	-
GNS2_k127_2704368_5	1077972.ARGLB_058_00630	0.0007322	46.0	COG4276@1|root,COG4276@2|Bacteria,2ISSK@201174|Actinobacteria	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GNS2_k127_2704368_4	378806.STAUR_7212	0.0003627	47.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2YXST@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GNS2_k127_271073_0	671143.DAMO_2418	7.762e-111	370.0	COG0452@1|root,COG0452@2|Bacteria,2NNX9@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GNS2_k127_271073_3	204669.Acid345_3777	9.656e-05	54.0	COG1758@1|root,COG1758@2|Bacteria,3Y5Z6@57723|Acidobacteria,2JK65@204432|Acidobacteriia	204432|Acidobacteriia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
GNS2_k127_271073_1	1125863.JAFN01000001_gene1800	1.083e-54	198.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GNS2_k127_271073_2	290397.Adeh_2607	2.946e-24	106.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GNS2_k127_2745803_3	671143.DAMO_1672	2.383e-62	220.0	COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GNS2_k127_2745803_1	1201288.M900_0271	2.271e-133	428.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
GNS2_k127_2745803_2	886293.Sinac_1831	2.906e-117	387.0	COG1290@1|root,COG1290@2|Bacteria,2IYI0@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
GNS2_k127_2745803_0	1201290.M902_1286	5.943e-165	555.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2MUN1@213481|Bdellovibrionales,2WPS4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GNS2_k127_2745803_4	1089547.KB913013_gene3593	6.112e-29	120.0	COG3266@1|root,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GNS2_k127_275185_1	1048834.TC41_0310	7.294e-06	54.0	2EH4F@1|root,33AWE@2|Bacteria,1UC9C@1239|Firmicutes,4HYKA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_275185_2	114615.BRADO2238	1.602e-05	57.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Lipase_GDSL_2
GNS2_k127_275185_0	1267534.KB906756_gene67	2.094e-06	58.0	COG4232@1|root,COG4232@2|Bacteria,3Y5CU@57723|Acidobacteria,2JJSZ@204432|Acidobacteriia	204432|Acidobacteriia	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
GNS2_k127_275185_3	634177.GLX_10880	6.84e-05	53.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2JS6P@204441|Rhodospirillales	204441|Rhodospirillales	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GNS2_k127_2781752_2	1121396.KB893001_gene3951	2.399e-17	94.0	COG2067@1|root,COG2067@2|Bacteria,1NHG3@1224|Proteobacteria	1224|Proteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
GNS2_k127_2781752_0	1499967.BAYZ01000105_gene3517	9.384e-26	119.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
GNS2_k127_2781752_1	324602.Caur_0081	2.599e-21	100.0	2EEXH@1|root,338QV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
GNS2_k127_2781775_1	649638.Trad_0889	3.218e-47	175.0	COG3597@1|root,COG3597@2|Bacteria	2|Bacteria	S	protein domain associated with	ycgC	-	-	ko:K03595,ko:K06883,ko:K06946	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF697,MMR_HSR1
GNS2_k127_2781775_0	861299.J421_0835	6.826e-58	226.0	2DQ6W@1|root,3350G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2781775_2	1403819.BATR01000130_gene4662	1.247e-07	65.0	28IVM@1|root,2Z8U0@2|Bacteria,46S57@74201|Verrucomicrobia,2IVM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2825931_0	1227739.Hsw_3104	4.825e-05	57.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,47JEP@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GNS2_k127_2826683_10	717606.PaecuDRAFT_3837	7.889e-07	50.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GNS2_k127_2826683_2	697281.Mahau_1643	1.454e-104	354.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,42FR9@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GNS2_k127_2826683_0	639282.DEFDS_0066	4.245e-174	576.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2GF31@200930|Deferribacteres	200930|Deferribacteres	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GNS2_k127_2826683_7	1120950.KB892799_gene2147	6.734e-50	205.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GNS2_k127_2826683_9	402881.Plav_3469	3.26e-23	108.0	2EHM5@1|root,33BCX@2|Bacteria,1NECF@1224|Proteobacteria,2UJ15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2826683_5	272943.RSP_3379	6.07e-58	207.0	2DMDM@1|root,32Q85@2|Bacteria,1RGD5@1224|Proteobacteria	1224|Proteobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
GNS2_k127_2826683_1	1121028.ARQE01000001_gene3580	9.931e-106	353.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,2TVQV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GNS2_k127_2826683_8	1116472.MGMO_137c00120	6.06e-41	160.0	2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria,1XGHH@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2826683_4	330214.NIDE2970	8.091e-72	253.0	COG0084@1|root,COG0084@2|Bacteria,3J0KM@40117|Nitrospirae	40117|Nitrospirae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
GNS2_k127_2826683_6	1120973.AQXL01000134_gene1677	2.525e-55	210.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,278D5@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GNS2_k127_2826683_3	1125863.JAFN01000001_gene236	4.449e-77	267.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GNS2_k127_2837604_2	324057.Pjdr2_4684	2.763e-13	70.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,26SM7@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GNS2_k127_2837604_0	404589.Anae109_4113	7.795e-205	655.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GNS2_k127_2837604_1	1121920.AUAU01000021_gene2509	5.847e-46	170.0	COG0674@1|root,COG0674@2|Bacteria,3Y3NB@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.7	ko:K00186	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
GNS2_k127_285015_9	234267.Acid_4535	6.201e-110	362.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GNS2_k127_285015_3	479434.Sthe_2317	4.801e-153	503.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,27YVX@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
GNS2_k127_285015_7	1382306.JNIM01000001_gene765	1.181e-126	418.0	COG0176@1|root,COG0176@2|Bacteria,2GA93@200795|Chloroflexi	200795|Chloroflexi	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GNS2_k127_285015_0	478741.JAFS01000002_gene71	2.839e-292	917.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,37G0P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GNS2_k127_285015_4	765420.OSCT_2525	1.252e-144	481.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	prk	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
GNS2_k127_285015_6	765420.OSCT_2524	2.051e-129	423.0	COG0464@1|root,COG0464@2|Bacteria,2G8T4@200795|Chloroflexi	200795|Chloroflexi	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GNS2_k127_285015_10	671143.DAMO_2166	3.288e-64	229.0	COG4451@1|root,COG4451@2|Bacteria	2|Bacteria	C	ribulose-bisphosphate carboxylase activity	cbbS	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
GNS2_k127_285015_1	671143.DAMO_2165	1.402e-273	848.0	COG1850@1|root,COG1850@2|Bacteria,2NQ96@2323|unclassified Bacteria	2|Bacteria	G	Ribulose bisphosphate carboxylase large chain, N-terminal domain	cbbL	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
GNS2_k127_285015_5	671143.DAMO_0861	8.101e-135	436.0	COG0583@1|root,COG0583@2|Bacteria,2NR37@2323|unclassified Bacteria	2|Bacteria	K	LysR substrate binding domain	cbbR	-	-	ko:K21703,ko:K21711	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
GNS2_k127_285015_2	671143.DAMO_0098	3.655e-166	550.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GNS2_k127_285015_8	525904.Tter_0579	1.873e-114	383.0	COG0801@1|root,COG1469@1|root,COG0801@2|Bacteria,COG1469@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25	ko:K00950,ko:K09007,ko:K13940,ko:K17488	ko00790,ko01100,map00790,map01100	M00126,M00841	R00428,R03503,R03504,R04639,R05046,R05048,R10348	RC00002,RC00017,RC00263,RC00294,RC00323,RC00721,RC00943,RC00945,RC01188,RC02504,RC03131	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
GNS2_k127_2876957_4	1122179.KB890414_gene1905	1.142e-12	82.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
GNS2_k127_2876957_0	1120965.AUBV01000001_gene3486	1.479e-229	745.0	COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GNS2_k127_2876957_1	926549.KI421517_gene3389	3.869e-84	286.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,47R25@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
GNS2_k127_2876957_2	1191523.MROS_0414	3.389e-62	220.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GNS2_k127_2876957_3	497964.CfE428DRAFT_4723	3.138e-47	183.0	COG1512@1|root,COG1512@2|Bacteria,46T36@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GNS2_k127_2877181_3	234267.Acid_5235	1.688e-144	479.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GNS2_k127_2877181_7	1267535.KB906767_gene2360	2.953e-38	159.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GNS2_k127_2877181_4	1132442.KB889752_gene2152	1.35e-93	326.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GNS2_k127_2877181_2	204669.Acid345_3056	5.017e-146	476.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria,2JIKE@204432|Acidobacteriia	204432|Acidobacteriia	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
GNS2_k127_2877181_0	247490.KSU1_D0853	4.368e-162	542.0	COG5001@1|root,COG5001@2|Bacteria,2IY4F@203682|Planctomycetes	203682|Planctomycetes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
GNS2_k127_2877181_1	886293.Sinac_1427	3.352e-150	487.0	COG0213@1|root,COG0213@2|Bacteria,2IY57@203682|Planctomycetes	203682|Planctomycetes	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GNS2_k127_2877181_8	1267535.KB906767_gene110	3.627e-09	70.0	2DF3Q@1|root,2ZQCR@2|Bacteria,3Y8YJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_2877181_5	1157490.EL26_16960	1.79e-55	212.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,2785U@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GNS2_k127_2877181_6	338963.Pcar_1219	2.509e-50	192.0	COG2378@1|root,COG2378@2|Bacteria,1PE00@1224|Proteobacteria,42T67@68525|delta/epsilon subdivisions,2WMIA@28221|Deltaproteobacteria,43S9S@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
GNS2_k127_2892707_2	1047013.AQSP01000132_gene1731	2.16e-67	245.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	-	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
GNS2_k127_2892707_1	404589.Anae109_0135	1.707e-151	504.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
GNS2_k127_2892707_0	1173022.Cri9333_0095	5.022e-309	957.0	COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria,1H95S@1150|Oscillatoriales	1117|Cyanobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GNS2_k127_2892707_3	391625.PPSIR1_22931	1.933e-50	188.0	COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,42M9H@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_2926115_4	861299.J421_3426	1.802e-18	99.0	COG0527@1|root,COG0527@2|Bacteria,1ZSXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GNS2_k127_2926115_1	309801.trd_0366	1.161e-115	382.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GNS2_k127_2926115_0	247490.KSU1_D0957	1.188e-125	413.0	COG0232@1|root,COG0232@2|Bacteria,2IX8F@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
GNS2_k127_2926115_2	278963.ATWD01000001_gene3516	1.852e-107	371.0	COG0591@1|root,COG0591@2|Bacteria,3Y8UG@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GNS2_k127_2926115_3	682795.AciX8_4813	1.565e-29	121.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria,2JI4Z@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
GNS2_k127_2956066_1	204669.Acid345_3352	8.977e-118	396.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria,2JM46@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GNS2_k127_2956066_2	518766.Rmar_2217	1.008e-85	323.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1FJZG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
GNS2_k127_2956066_0	518766.Rmar_0925	7.759e-222	725.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
GNS2_k127_2956066_3	926554.KI912633_gene3723	1.953e-36	153.0	COG1649@1|root,COG1649@2|Bacteria,1WM1V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
GNS2_k127_2956066_4	861299.J421_3061	2.087e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
GNS2_k127_2974338_4	403833.Pmob_1728	5.548e-06	51.0	COG0498@1|root,COG0498@2|Bacteria,2GC48@200918|Thermotogae	200918|Thermotogae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_2974338_3	1160137.KB907308_gene7665	5.745e-12	76.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4FV21@85025|Nocardiaceae	201174|Actinobacteria	P	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
GNS2_k127_2974338_2	404589.Anae109_1726	9.316e-31	134.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GNS2_k127_2974338_0	1304874.JAFY01000007_gene2147	4.789e-148	482.0	COG0031@1|root,COG0031@2|Bacteria,3T9XD@508458|Synergistetes	508458|Synergistetes	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
GNS2_k127_2974338_1	502025.Hoch_5969	5.9e-55	203.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2Z0Y2@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GNS2_k127_2975574_0	768710.DesyoDRAFT_5296	2.932e-149	482.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GNS2_k127_2975574_1	234267.Acid_6604	1.14e-28	130.0	COG1413@1|root,COG1413@2|Bacteria,3Y6AH@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GNS2_k127_298000_8	565045.NOR51B_2091	1.139e-13	87.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1J546@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ytfN	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GNS2_k127_298000_6	234267.Acid_3949	1.436e-31	146.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
GNS2_k127_298000_1	402626.Rpic_3767	3.522e-180	573.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K375@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	zraR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_298000_3	1254432.SCE1572_26500	2.012e-119	404.0	COG0642@1|root,COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
GNS2_k127_298000_7	330214.NIDE1248	8.227e-16	85.0	COG1734@1|root,COG1734@2|Bacteria,3J0R1@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GNS2_k127_298000_0	290397.Adeh_3184	0.0	3550.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
GNS2_k127_298000_2	292415.Tbd_2258	2.443e-136	443.0	COG0673@1|root,COG0673@2|Bacteria,1PF0E@1224|Proteobacteria,2W9B2@28216|Betaproteobacteria,1KTHN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GNS2_k127_298000_5	313612.L8106_12410	1.196e-35	151.0	COG1476@1|root,COG2856@1|root,COG1476@2|Bacteria,COG2856@2|Bacteria,1G33E@1117|Cyanobacteria,1HA1N@1150|Oscillatoriales	1117|Cyanobacteria	K	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78,UPF0175
GNS2_k127_298000_4	1502852.FG94_04582	1.58e-42	160.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria,477PW@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3003943_3	246197.MXAN_3258	5.269e-41	157.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
GNS2_k127_3003943_2	1297742.A176_02650	5.984e-60	222.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria,2YVDV@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GNS2_k127_3003943_1	378806.STAUR_3693	5.704e-61	232.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GNS2_k127_3003943_4	1242864.D187_007128	1.154e-28	124.0	COG2332@1|root,COG2332@2|Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GNS2_k127_3003943_0	1278073.MYSTI_04691	5.045e-154	507.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GNS2_k127_3021068_20	546269.HMPREF0389_00839	1.978e-11	67.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25RVP@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
GNS2_k127_3021068_17	1121468.AUBR01000044_gene1852	2e-19	94.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
GNS2_k127_3021068_8	1382359.JIAL01000001_gene1706	2.207e-55	196.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
GNS2_k127_3021068_15	1121472.AQWN01000002_gene2051	3.274e-28	127.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,26260@186807|Peptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
GNS2_k127_3021068_4	635013.TherJR_0308	8.645e-73	256.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
GNS2_k127_3021068_16	671143.DAMO_0552	2.819e-25	105.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
GNS2_k127_3021068_9	1267534.KB906757_gene807	5.511e-53	191.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria,2JJ74@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
GNS2_k127_3021068_6	1267533.KB906735_gene5115	1.332e-59	212.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria,2JJ4H@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
GNS2_k127_3021068_13	2423.NA23_0208125	3.891e-40	151.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
GNS2_k127_3021068_7	883156.HMPREF9282_00770	1.659e-58	212.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4H3Z7@909932|Negativicutes	909932|Negativicutes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GNS2_k127_3021068_19	580332.Slit_0785	6.234e-13	72.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
GNS2_k127_3021068_12	858215.Thexy_0353	5.634e-48	176.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GNS2_k127_3021068_0	1047013.AQSP01000074_gene1894	5.779e-183	591.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GNS2_k127_3021068_5	867903.ThesuDRAFT_00579	2.397e-62	222.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WCG7@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
GNS2_k127_3021068_2	926561.KB900619_gene2568	5.625e-91	306.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GNS2_k127_3021068_18	591001.Acfer_1907	2.376e-13	73.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4H53Q@909932|Negativicutes	909932|Negativicutes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GNS2_k127_3021068_21	694431.DESACE_01960	5.216e-08	61.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GNS2_k127_3021068_11	697303.Thewi_2230	2.509e-50	181.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GNS2_k127_3021068_10	204669.Acid345_1252	1.484e-51	185.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GNS2_k127_3021068_3	240015.ACP_1424	5.262e-80	271.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria,2JHR6@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GNS2_k127_3021068_1	639030.JHVA01000001_gene1527	6.531e-139	449.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GNS2_k127_3021068_14	234267.Acid_5089	7.62e-35	140.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GNS2_k127_3036131_2	1173024.KI912148_gene2485	1.154e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1G4QN@1117|Cyanobacteria,1JH6D@1189|Stigonemataceae	1117|Cyanobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GNS2_k127_3036131_0	1262449.CP6013_0354	3.467e-180	586.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,247WK@186801|Clostridia,36VS3@31979|Clostridiaceae	186801|Clostridia	FH	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GNS2_k127_3036131_1	1382358.JHVN01000013_gene1800	4.443e-169	542.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli	91061|Bacilli	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GNS2_k127_3045299_0	1173028.ANKO01000092_gene4381	1.718e-84	291.0	COG0515@1|root,COG0515@2|Bacteria	1173028.ANKO01000092_gene4381|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3045299_1	485913.Krac_0646	6.757e-61	215.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2G8MA@200795|Chloroflexi	2|Bacteria	H	COGs COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cytochrom_c3_2,FHA,Pkinase
GNS2_k127_3053485_1	401053.AciPR4_1257	6.427e-12	73.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
GNS2_k127_3053485_0	1379698.RBG1_1C00001G0370	6.404e-130	432.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
GNS2_k127_3068205_1	234267.Acid_4549	1.416e-06	52.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3068205_0	1382306.JNIM01000001_gene371	2.049e-86	296.0	COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_3068205_2	1214242.B446_17140	0.0001708	55.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
GNS2_k127_3100725_1	1174528.JH992898_gene5117	6.275e-32	128.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	1174528.JH992898_gene5117|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3100725_0	861299.J421_1968	9.344e-34	143.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GNS2_k127_3100725_5	469383.Cwoe_0106	2.349e-05	57.0	COG0741@1|root,COG0741@2|Bacteria,2HQ39@201174|Actinobacteria,4CRJS@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GNS2_k127_3100725_3	706587.Desti_4096	4.593e-06	55.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MQWB@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GNS2_k127_3100725_4	1173023.KE650771_gene551	1.554e-05	54.0	2DM1K@1|root,31BCJ@2|Bacteria,1G6WG@1117|Cyanobacteria,1JIVN@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3100725_2	1144275.COCOR_02332	1.419e-12	70.0	2BV6E@1|root,32QJT@2|Bacteria,1Q8U0@1224|Proteobacteria,43E1K@68525|delta/epsilon subdivisions,2WZFI@28221|Deltaproteobacteria,2Z215@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3109299_1	1121920.AUAU01000005_gene1059	2.034e-40	156.0	2B9NZ@1|root,3231D@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GNS2_k127_3109299_2	1282362.AEAC466_05545	6.895e-19	99.0	2BTYK@1|root,32P72@2|Bacteria,1Q8R0@1224|Proteobacteria,2UXQW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3109299_0	1042377.AFPJ01000028_gene2288	9.604e-222	698.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,466AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
GNS2_k127_3121810_0	1267535.KB906767_gene4295	1.994e-34	137.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GNS2_k127_3121810_3	309801.trd_1639	4.047e-11	75.0	COG0576@1|root,COG0576@2|Bacteria,2G6WR@200795|Chloroflexi,27YDX@189775|Thermomicrobia	189775|Thermomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GNS2_k127_3121810_1	1123229.AUBC01000029_gene3509	5.628e-26	119.0	COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,3JVZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	UbiA prenyltransferase family	bchG	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
GNS2_k127_3121810_2	197221.22296112	1.792e-25	109.0	COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
GNS2_k127_3129368_4	552811.Dehly_0351	3.439e-113	376.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,34CVS@301297|Dehalococcoidia	301297|Dehalococcoidia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
GNS2_k127_3129368_14	760568.Desku_0644	2.59e-40	159.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,265M1@186807|Peptococcaceae	186801|Clostridia	J	RNA 2'-O ribose methyltransferase substrate binding	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GNS2_k127_3129368_11	234267.Acid_6710	8.237e-47	173.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria	57723|Acidobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GNS2_k127_3129368_19	398767.Glov_0579	7.754e-12	76.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
GNS2_k127_3129368_5	1379698.RBG1_1C00001G1614	4.57e-104	350.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GNS2_k127_3129368_1	1267535.KB906767_gene1558	5.29e-185	597.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GNS2_k127_3129368_7	234267.Acid_3219	8.254e-76	287.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3129368_16	1267535.KB906767_gene3681	2.653e-26	120.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GNS2_k127_3129368_2	204669.Acid345_1066	3.845e-126	422.0	COG1404@1|root,COG1409@1|root,COG3055@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JMMV@204432|Acidobacteriia	204432|Acidobacteriia	GO	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH
GNS2_k127_3129368_6	234267.Acid_3589	3.807e-101	346.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
GNS2_k127_3129368_20	1196323.ALKF01000191_gene5572	0.0006963	48.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,4HNC2@91061|Bacilli,26XID@186822|Paenibacillaceae	91061|Bacilli	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GNS2_k127_3129368_0	401053.AciPR4_1799	3.897e-291	908.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GNS2_k127_3129368_3	1192034.CAP_9010	7.995e-121	391.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,42PJM@68525|delta/epsilon subdivisions,2WKJN@28221|Deltaproteobacteria,2Z0J4@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GNS2_k127_3129368_12	1278073.MYSTI_02024	8.689e-41	174.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phosphodiest
GNS2_k127_3129368_9	512565.AMIS_76020	2.124e-66	242.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4DBGR@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GNS2_k127_3129368_17	525378.HMPREF0793_1363	1.293e-23	112.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,4GX6B@90964|Staphylococcaceae	91061|Bacilli	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
GNS2_k127_3129368_18	1123073.KB899242_gene1378	3.873e-12	79.0	2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3129368_13	1242864.D187_000493	1.123e-40	155.0	COG4639@1|root,COG4639@2|Bacteria,1PZMV@1224|Proteobacteria,43874@68525|delta/epsilon subdivisions,2X3H2@28221|Deltaproteobacteria,2YW27@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GNS2_k127_3129368_8	1123368.AUIS01000001_gene2032	2.335e-74	261.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
GNS2_k127_3129368_10	76114.ebA6810	1.026e-62	231.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KUHC@206389|Rhodocyclales	206389|Rhodocyclales	I	Squalene synthase HpnD	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
GNS2_k127_3136209_0	234267.Acid_0497	4.892e-120	395.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
GNS2_k127_3136209_1	886293.Sinac_3660	1.497e-77	269.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GNS2_k127_3140540_0	264732.Moth_1998	5.253e-124	406.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia,42J3Q@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_3140540_1	234267.Acid_7676	7.152e-94	325.0	COG2234@1|root,COG2234@2|Bacteria,3Y43U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GNS2_k127_3140540_2	1278073.MYSTI_02537	5.421e-64	239.0	COG2234@1|root,COG2234@2|Bacteria,1NVWC@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GNS2_k127_3143522_1	766499.C357_23070	5.04e-63	227.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
GNS2_k127_3143522_4	637389.Acaty_c2094	1.977e-27	126.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,1SDDS@1236|Gammaproteobacteria,2NC9Y@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GNS2_k127_3143522_0	1385935.N836_10100	2.28e-76	284.0	COG0438@1|root,COG0438@2|Bacteria,1G4KT@1117|Cyanobacteria,1HCQM@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
GNS2_k127_3143522_2	329726.AM1_2715	1.262e-52	201.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GNS2_k127_3143522_5	935863.AWZR01000006_gene1367	1.47e-12	76.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1X489@135614|Xanthomonadales	135614|Xanthomonadales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GNS2_k127_3143522_3	926550.CLDAP_27740	2.447e-33	148.0	COG2244@1|root,COG2244@2|Bacteria,2G8GU@200795|Chloroflexi	200795|Chloroflexi	S	virulence factor MVIN family protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GNS2_k127_3143522_7	525897.Dbac_1114	2.656e-05	54.0	2EPQB@1|root,33HAX@2|Bacteria,1NGGD@1224|Proteobacteria,42XQZ@68525|delta/epsilon subdivisions,2WT07@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
GNS2_k127_3143522_6	314275.MADE_1003080	6.215e-10	63.0	COG3668@1|root,COG3668@2|Bacteria,1N7PN@1224|Proteobacteria,1T0H4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GNS2_k127_3153706_0	867903.ThesuDRAFT_01691	2.782e-118	405.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3WCCA@538999|Clostridiales incertae sedis	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GNS2_k127_3153706_1	682795.AciX8_0742	1.367e-83	285.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
GNS2_k127_3208124_4	401053.AciPR4_1259	1.487e-08	59.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GNS2_k127_3208124_3	335543.Sfum_1416	1.954e-14	80.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MP@1224|Proteobacteria,437C9@68525|delta/epsilon subdivisions,2X2HS@28221|Deltaproteobacteria,2MQR0@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GNS2_k127_3208124_0	243231.GSU1765	7.183e-80	281.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GNS2_k127_3208124_2	234267.Acid_1115	5.287e-61	232.0	COG1189@1|root,COG1189@2|Bacteria,3Y3HM@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GNS2_k127_3208124_1	404380.Gbem_2445	1.031e-74	277.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GNS2_k127_3232103_3	1123388.AQWU01000048_gene508	2.878e-41	157.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GNS2_k127_3232103_2	1379698.RBG1_1C00001G0700	6.223e-165	537.0	COG0427@1|root,COG0427@2|Bacteria,2NQDP@2323|unclassified Bacteria	2|Bacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GNS2_k127_3232103_1	926569.ANT_14860	2.54e-167	536.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GNS2_k127_3232103_4	472759.Nhal_1656	2.117e-10	69.0	COG1652@1|root,COG2010@1|root,COG1652@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,DUF4157,LysM
GNS2_k127_3232103_0	1121920.AUAU01000001_gene2268	4.325e-221	705.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
GNS2_k127_3232103_5	1120950.KB892763_gene5580	1.232e-06	54.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4DPKX@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_323918_2	1396418.BATQ01000186_gene2147	7.246e-34	152.0	2BVHD@1|root,32QVZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_323918_0	96561.Dole_0625	6.618e-65	235.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GNS2_k127_323918_1	580331.Thit_1043	1.228e-40	156.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,42GK6@68295|Thermoanaerobacterales	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GNS2_k127_324517_7	391598.FBBAL38_08814	4.78e-31	130.0	COG1357@1|root,COG5295@1|root,COG1357@2|Bacteria,COG5295@2|Bacteria,4PMQQ@976|Bacteroidetes	976|Bacteroidetes	UW	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
GNS2_k127_324517_3	1047013.AQSP01000091_gene649	3.956e-100	357.0	COG2227@1|root,COG3408@1|root,COG2227@2|Bacteria,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,CBM_6,Crystall,Glyco_hydro_64,Methyltransf_11,Methyltransf_23,RicinB_lectin_2,SLH
GNS2_k127_324517_5	1128421.JAGA01000002_gene1141	1.444e-71	250.0	COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria	2|Bacteria	I	Enoyl-CoA hydratase/isomerase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GNS2_k127_324517_0	1382306.JNIM01000001_gene2570	1.589e-255	799.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GNS2_k127_324517_1	1254432.SCE1572_18340	7.578e-164	526.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GNS2_k127_324517_9	28229.ND2E_3536	3.512e-16	84.0	2DSYW@1|root,33HZI@2|Bacteria,1NKP8@1224|Proteobacteria,1SISV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_324517_10	1192034.CAP_8320	1.3e-06	58.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GNS2_k127_324517_12	1123053.AUDG01000001_gene2390	0.0002943	51.0	2E0TQ@1|root,32WBD@2|Bacteria,1N4HN@1224|Proteobacteria,1SC43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_324517_8	251229.Chro_1245	7.53e-22	108.0	COG1748@1|root,COG1748@2|Bacteria,1G3B5@1117|Cyanobacteria,3VHQW@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
GNS2_k127_324517_6	861299.J421_3649	8.11e-47	192.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GNS2_k127_324517_4	1382306.JNIM01000001_gene3863	4.871e-88	316.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_324517_2	1121468.AUBR01000045_gene1802	3.308e-100	338.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GNS2_k127_3314795_2	706587.Desti_1107	3.586e-44	184.0	COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GNS2_k127_3314795_3	1131812.JQMS01000001_gene2495	2.507e-28	132.0	COG3184@1|root,COG3184@2|Bacteria,4NSCK@976|Bacteroidetes,1I5E8@117743|Flavobacteriia,2NXBF@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
GNS2_k127_3314795_4	1382356.JQMP01000004_gene531	2.261e-27	129.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3314795_1	861299.J421_0333	1.621e-137	464.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GNS2_k127_3314795_0	926550.CLDAP_00650	6.321e-293	918.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GNS2_k127_3318021_5	1267535.KB906767_gene4160	1.613e-05	51.0	COG2304@1|root,COG2304@2|Bacteria,3Y99W@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GNS2_k127_3318021_2	234267.Acid_4520	9.297e-36	144.0	COG1335@1|root,COG1335@2|Bacteria,3Y7ZP@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
GNS2_k127_3318021_1	1128421.JAGA01000002_gene101	2.516e-40	165.0	COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria	2|Bacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GNS2_k127_3318021_3	614083.AWQR01000025_gene3719	9.917e-20	90.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3318021_0	298654.FraEuI1c_1723	9.102e-63	234.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
GNS2_k127_3318021_4	494419.ALPM01000013_gene667	7.695e-14	79.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,1W9G2@1268|Micrococcaceae	201174|Actinobacteria	T	Forkhead associated domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
GNS2_k127_33283_2	1116472.MGMO_94c00210	5.229e-97	323.0	COG1028@1|root,COG1028@2|Bacteria,1QWF5@1224|Proteobacteria,1T5MF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GNS2_k127_33283_1	1210884.HG799467_gene13160	1.313e-125	421.0	COG0673@1|root,COG0673@2|Bacteria,2J0EQ@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GNS2_k127_33283_0	671143.DAMO_0938	3.681e-150	482.0	COG2605@1|root,COG2605@2|Bacteria,2NP6Q@2323|unclassified Bacteria	2|Bacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_33283_3	671143.DAMO_0939	2.815e-40	166.0	COG1208@1|root,COG1208@2|Bacteria,2NR93@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
GNS2_k127_3332205_1	1232410.KI421413_gene687	1.798e-187	594.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43SDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GNS2_k127_3332205_4	338963.Pcar_1441	7.297e-44	166.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,43UNK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
GNS2_k127_3332205_3	441620.Mpop_3207	2.993e-62	219.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2U05J@28211|Alphaproteobacteria,1JT3M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
GNS2_k127_3332205_5	1379698.RBG1_1C00001G0657	2.717e-35	148.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GNS2_k127_3332205_2	1267535.KB906767_gene4678	3.383e-114	379.0	COG1092@1|root,COG1092@2|Bacteria,3Y2PV@57723|Acidobacteria,2JICM@204432|Acidobacteriia	204432|Acidobacteriia	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GNS2_k127_3332205_0	926550.CLDAP_07340	0.0	1107.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GNS2_k127_3332205_6	215803.DB30_2655	1.062e-21	108.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
GNS2_k127_3332205_7	1349767.GJA_3726	5.126e-06	59.0	COG5498@1|root,COG5498@2|Bacteria,1R4DU@1224|Proteobacteria,2VPUP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_81
GNS2_k127_3347459_2	1118235.CAJH01000046_gene2927	4.989e-55	203.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RYH1@1236|Gammaproteobacteria,1X4YV@135614|Xanthomonadales	135614|Xanthomonadales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GNS2_k127_3347459_0	240015.ACP_0332	7.137e-137	467.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
GNS2_k127_3347459_4	246197.MXAN_1246	5.735e-45	171.0	COG1051@1|root,COG1051@2|Bacteria,1NA5A@1224|Proteobacteria,433DA@68525|delta/epsilon subdivisions,2WYEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GNS2_k127_3347459_3	118168.MC7420_6357	1.099e-53	217.0	COG2730@1|root,COG2931@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,1G314@1117|Cyanobacteria,1HAD6@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Calx-beta,Glyco_hydro_9
GNS2_k127_3347459_1	869210.Marky_0500	6.898e-102	368.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GNS2_k127_3347459_8	1183438.GKIL_0937	1.445e-07	61.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	urtB	-	-	ko:K05386,ko:K11960	ko00196,ko01100,ko02010,map00196,map01100,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko00194,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2,HEAT_2
GNS2_k127_3347459_10	391165.GbCGDNIH1_1599	4.46e-06	57.0	2C110@1|root,32TCF@2|Bacteria,1NXUA@1224|Proteobacteria,2USVH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3347459_7	1038860.AXAP01000202_gene6017	2.502e-09	64.0	COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,2UHUN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GNS2_k127_3347459_9	1381123.AYOD01000001_gene951	1.22e-06	57.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,43JRQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
GNS2_k127_3347459_6	1380394.JADL01000012_gene940	1.449e-41	156.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2JSC3@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
GNS2_k127_3347459_5	215803.DB30_0685	4.665e-42	157.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GNS2_k127_3364188_2	1254432.SCE1572_44415	1.498e-130	439.0	COG1404@1|root,COG1404@2|Bacteria,1PEJJ@1224|Proteobacteria,438RE@68525|delta/epsilon subdivisions,2X3YD@28221|Deltaproteobacteria,2YXKA@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GNS2_k127_3364188_3	234267.Acid_4415	2.374e-122	404.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GNS2_k127_3364188_4	1408224.SAMCCGM7_c4433	3.42e-114	394.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TV07@28211|Alphaproteobacteria,4B9X5@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GNS2_k127_3364188_5	82654.Pse7367_2149	2.935e-79	282.0	COG2755@1|root,COG2755@2|Bacteria,1G3BA@1117|Cyanobacteria	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
GNS2_k127_3364188_10	1523503.JPMY01000045_gene29	6.555e-46	177.0	COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1SCQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
GNS2_k127_3364188_9	1565129.JSFF01000047_gene604	3.963e-49	188.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,2Q8HB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GNS2_k127_3364188_8	195250.CM001776_gene1111	9.434e-51	191.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GNS2_k127_3364188_13	234267.Acid_0781	3.176e-11	73.0	COG0697@1|root,COG0697@2|Bacteria,3Y4XS@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GNS2_k127_3364188_7	639030.JHVA01000001_gene1782	9.822e-55	197.0	COG2318@1|root,COG2318@2|Bacteria,3Y5FN@57723|Acidobacteria,2JJTU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GNS2_k127_3364188_6	251221.35212585	3.57e-55	199.0	COG0122@1|root,COG0122@2|Bacteria,1G394@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GNS2_k127_3364188_12	671143.DAMO_2204	4.257e-29	119.0	2DNYI@1|root,32ZT2@2|Bacteria	2|Bacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
GNS2_k127_3364188_1	448385.sce3620	3.163e-206	653.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120	-	R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh
GNS2_k127_3364188_0	204669.Acid345_2328	3.493e-268	844.0	COG1770@1|root,COG1770@2|Bacteria,3Y3PK@57723|Acidobacteria,2JIWT@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GNS2_k127_3364188_11	977880.RALTA_A3049	2.71e-39	150.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
GNS2_k127_3364188_14	457570.Nther_2188	3.744e-09	63.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GNS2_k127_3393307_7	227882.SAV_3653	6.15e-40	161.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria	201174|Actinobacteria	IQ	reductase	phbB	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GNS2_k127_3393307_6	1444712.BN1013_02048	4.781e-42	174.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	pksI	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	ko:K15313	-	-	-	-	ko00000,ko01008	-	-	-	ECH_1
GNS2_k127_3393307_2	1444712.BN1013_02049	2.841e-58	222.0	COG1028@1|root,COG1028@2|Bacteria	1444712.BN1013_02049|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3393307_11	391625.PPSIR1_34382	5.39e-13	81.0	COG0764@1|root,COG0764@2|Bacteria,1NF10@1224|Proteobacteria,43217@68525|delta/epsilon subdivisions,2WWWK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GNS2_k127_3393307_9	1444712.BN1013_02052	1.032e-19	91.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpK	-	-	ko:K02078,ko:K15337	-	-	-	-	ko00000,ko00001,ko01008	-	-	-	PP-binding
GNS2_k127_3393307_0	1444712.BN1013_02053	3.886e-142	465.0	COG0304@1|root,COG0304@2|Bacteria,2JFJJ@204428|Chlamydiae	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	pksF	-	2.3.1.179,2.3.1.41	ko:K00646,ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GNS2_k127_3393307_13	1120973.AQXL01000131_gene2110	1.805e-09	71.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,279C6@186823|Alicyclobacillaceae	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
GNS2_k127_3393307_3	383372.Rcas_0623	1.691e-56	208.0	COG2230@1|root,COG2230@2|Bacteria,2G9AF@200795|Chloroflexi,3780F@32061|Chloroflexia	32061|Chloroflexia	H	UbiE COQ5 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_3393307_1	1123242.JH636435_gene2917	4.636e-92	335.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GNS2_k127_3393307_14	397945.Aave_4149	0.0001084	52.0	2E8SE@1|root,33338@2|Bacteria,1PTYJ@1224|Proteobacteria,2VWN5@28216|Betaproteobacteria,4AFR9@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3393307_8	1379281.AVAG01000067_gene1194	2.519e-34	144.0	COG4641@1|root,COG4641@2|Bacteria,1R64N@1224|Proteobacteria,42N73@68525|delta/epsilon subdivisions,2WM84@28221|Deltaproteobacteria,2M7XA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
GNS2_k127_3393307_4	1501230.ET33_09835	1.15e-55	206.0	COG1196@1|root,COG1196@2|Bacteria,1UP6E@1239|Firmicutes,4IV1J@91061|Bacilli,277SZ@186822|Paenibacillaceae	91061|Bacilli	D	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GNS2_k127_3393307_5	1169152.AXVD01000002_gene3734	1.298e-52	212.0	COG2227@1|root,COG2227@2|Bacteria,2GTJV@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GNS2_k127_3393307_10	1298863.AUEP01000001_gene924	1.83e-15	89.0	2BJD0@1|root,32DP6@2|Bacteria,2GS97@201174|Actinobacteria	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GNS2_k127_3451056_3	1173021.ALWA01000032_gene1085	1.183e-38	149.0	COG2885@1|root,COG2885@2|Bacteria,1G8PB@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_3451056_2	760568.Desku_1638	1.107e-90	310.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,2624Y@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GNS2_k127_3451056_0	1382356.JQMP01000004_gene194	4.972e-136	450.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,27Y3Q@189775|Thermomicrobia	189775|Thermomicrobia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GNS2_k127_3451056_4	344747.PM8797T_31795	6.489e-15	83.0	COG5126@1|root,COG5126@2|Bacteria,2J41T@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
GNS2_k127_3451056_1	867903.ThesuDRAFT_00861	1.342e-102	344.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
GNS2_k127_34975_1	880073.Calab_1578	3.333e-104	370.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GNS2_k127_34975_0	1382359.JIAL01000001_gene1920	1.949e-188	605.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GNS2_k127_34975_2	1278073.MYSTI_06920	2.292e-39	156.0	COG1451@1|root,COG1451@2|Bacteria,1P1X1@1224|Proteobacteria,4314C@68525|delta/epsilon subdivisions,2WX53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_351216_4	1121015.N789_02450	9.26e-05	49.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SH3N@1236|Gammaproteobacteria,1X4NY@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
GNS2_k127_351216_2	211165.AJLN01000104_gene6613	8.042e-23	102.0	COG3668@1|root,COG3668@2|Bacteria,1GKJ0@1117|Cyanobacteria,1JMAM@1189|Stigonemataceae	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GNS2_k127_351216_0	269799.Gmet_2367	6.886e-106	361.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
GNS2_k127_351216_1	243231.GSU2278	1.869e-104	348.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,43U2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GNS2_k127_3520435_5	644282.Deba_2421	1.989e-18	85.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,42PR0@68525|delta/epsilon subdivisions,2WMBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transferase hexapeptide repeat containing protein	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
GNS2_k127_3520435_3	1198114.AciX9_0583	1.266e-45	175.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_3520435_0	909663.KI867150_gene204	1.672e-105	348.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GNS2_k127_3520435_2	1210884.HG799467_gene13156	7.559e-56	200.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase,PRK
GNS2_k127_3520435_1	1210884.HG799467_gene13157	1.119e-92	307.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GNS2_k127_3520435_4	1210884.HG799467_gene13158	1.096e-33	133.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
GNS2_k127_3556133_2	1304880.JAGB01000001_gene512	3.924e-22	98.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GNS2_k127_3556133_0	401053.AciPR4_3799	3.231e-101	351.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria,2JIHT@204432|Acidobacteriia	204432|Acidobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
GNS2_k127_3556133_1	204669.Acid345_4296	1.798e-98	333.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GNS2_k127_3579300_2	204669.Acid345_2022	1.202e-75	262.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GNS2_k127_3579300_8	316278.SynRCC307_0652	4.438e-11	72.0	COG1842@1|root,COG1842@2|Bacteria,1G1GX@1117|Cyanobacteria,1GYX6@1129|Synechococcus	1117|Cyanobacteria	KT	Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
GNS2_k127_3579300_0	204669.Acid345_2676	1.259e-116	397.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GNS2_k127_3579300_5	204669.Acid345_4653	9.582e-21	100.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria,2JJK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GNS2_k127_3579300_4	1267533.KB906736_gene933	1.38e-26	124.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,3Y2GA@57723|Acidobacteria,2JHTQ@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
GNS2_k127_3579300_3	426117.M446_4341	5.215e-74	257.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1MUDV@1224|Proteobacteria,2TRXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
GNS2_k127_3579300_1	264732.Moth_0405	4.185e-108	371.0	COG4986@1|root,COG4986@2|Bacteria,1TRRR@1239|Firmicutes,248X4@186801|Clostridia,42HSS@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GNS2_k127_3579300_6	379066.GAU_1959	8.46e-18	95.0	2EQJ9@1|root,33I5A@2|Bacteria,1ZTSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3579300_7	357808.RoseRS_1787	1.523e-13	74.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3579300_9	1397696.KK211189_gene2556	6.558e-06	49.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_357977_5	234267.Acid_7493	3.119e-05	51.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_357977_4	1380350.JIAP01000001_gene1135	1.057e-06	60.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,2U8MR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
GNS2_k127_357977_2	383372.Rcas_3849	1.974e-13	80.0	COG2833@1|root,COG2833@2|Bacteria,2G9Q9@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
GNS2_k127_357977_0	1126627.BAWE01000004_gene2808	1.536e-16	93.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
GNS2_k127_357977_1	383372.Rcas_3849	9.016e-14	85.0	COG2833@1|root,COG2833@2|Bacteria,2G9Q9@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
GNS2_k127_357977_3	533247.CRD_02150	8.061e-10	72.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
GNS2_k127_357977_6	1104324.P186_1121	3.284e-05	56.0	COG0681@1|root,arCOG01739@2157|Archaea,2XR7N@28889|Crenarchaeota	28889|Crenarchaeota	U	TIGRFAM peptidase S26B, signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GNS2_k127_3583382_2	1047013.AQSP01000077_gene2268	1.455e-36	146.0	COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
GNS2_k127_3583382_1	1047013.AQSP01000077_gene2267	5.126e-81	282.0	COG0484@1|root,COG0484@2|Bacteria,2NNSJ@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GNS2_k127_3583382_0	1499967.BAYZ01000026_gene1569	4.699e-199	629.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GNS2_k127_3603292_6	326427.Cagg_1401	1.613e-57	211.0	COG0438@1|root,COG0438@2|Bacteria,2GABS@200795|Chloroflexi,3752C@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_3603292_2	635013.TherJR_1892	5.553e-74	280.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_3603292_1	331869.BAL199_21184	1.783e-88	317.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,2TU24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GNS2_k127_3603292_3	635013.TherJR_1892	1.136e-65	255.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_3603292_7	383372.Rcas_3055	2.125e-57	210.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi,375EP@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_3603292_0	324602.Caur_0982	3.194e-109	368.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GNS2_k127_3603292_8	1128421.JAGA01000002_gene1172	2.713e-54	207.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	mtfA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_3603292_5	338966.Ppro_2693	6.475e-59	213.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7KP@28221|Deltaproteobacteria,43V18@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_3603292_11	926566.Terro_3238	1.286e-05	54.0	COG0760@1|root,COG0760@2|Bacteria,3Y4KY@57723|Acidobacteria,2JJDJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
GNS2_k127_3603292_4	1267533.KB906733_gene3571	3.228e-62	246.0	COG0747@1|root,COG4775@1|root,COG0747@2|Bacteria,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
GNS2_k127_3603292_9	682795.AciX8_0647	7.815e-54	219.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
GNS2_k127_3603292_10	1297742.A176_03478	2.096e-24	108.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
GNS2_k127_3605301_1	1303518.CCALI_00704	5.422e-47	194.0	COG0642@1|root,COG2205@2|Bacteria	1303518.CCALI_00704|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3605301_0	1047013.AQSP01000083_gene1193	8.128e-60	239.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
GNS2_k127_3612505_4	1047013.AQSP01000124_gene2678	4.601e-25	112.0	COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria	2|Bacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GNS2_k127_3612505_6	338963.Pcar_2137	8.543e-12	77.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I2@1224|Proteobacteria,42VWH@68525|delta/epsilon subdivisions,2WS2H@28221|Deltaproteobacteria,43VGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
GNS2_k127_3612505_2	246197.MXAN_5776	9.848e-109	362.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
GNS2_k127_3612505_1	234267.Acid_7175	3.74e-134	434.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
GNS2_k127_3612505_0	1379698.RBG1_1C00001G0527	2.482e-161	533.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_3612505_3	204669.Acid345_1262	1.942e-65	234.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100,4.2.1.17	ko:K01715,ko:K07537	ko00362,ko00650,ko01100,ko01120,ko01200,ko01220,map00362,map00650,map01100,map01120,map01200,map01220	M00541	R03026,R05597	RC00831,RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GNS2_k127_3612505_5	1548153.LR59_04270	1.259e-18	85.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2YMES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_3662263_4	903818.KI912268_gene742	9.241e-40	171.0	28JI8@1|root,2Z9BM@2|Bacteria,3Y535@57723|Acidobacteria	57723|Acidobacteria	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
GNS2_k127_3662263_5	765177.Desmu_0449	3.059e-36	159.0	COG1524@1|root,COG3379@1|root,arCOG01377@2157|Archaea,arCOG01378@2157|Archaea,2XPVN@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GNS2_k127_3662263_1	555079.Toce_0711	1.002e-101	340.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_3662263_0	204669.Acid345_2499	2.261e-133	438.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338,M00609	R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02814,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
GNS2_k127_3662263_6	1242864.D187_009541	1.459e-26	126.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
GNS2_k127_3662263_2	326427.Cagg_0242	2.5e-46	171.0	COG2947@1|root,COG2947@2|Bacteria,2G93S@200795|Chloroflexi,375T3@32061|Chloroflexia	32061|Chloroflexia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GNS2_k127_3662263_9	1038869.AXAN01000205_gene2324	0.0008789	47.0	2DSZ1@1|root,33HZU@2|Bacteria,1PXZ0@1224|Proteobacteria,2WD9I@28216|Betaproteobacteria,1K9SN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3662263_8	1242864.D187_007940	1.296e-06	59.0	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
GNS2_k127_3662263_7	330214.NIDE4047	1.71e-22	101.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GNS2_k127_3662263_3	1197719.A464_1080	9.872e-41	155.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,3ZKG9@590|Salmonella	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
GNS2_k127_3677098_5	290397.Adeh_3941	3.037e-10	66.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QGI@68525|delta/epsilon subdivisions,2X5YV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GNS2_k127_3677098_4	452637.Oter_1459	1.25e-20	96.0	COG0640@1|root,COG0640@2|Bacteria,46WX7@74201|Verrucomicrobia	2|Bacteria	K	PFAM regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GNS2_k127_3677098_2	391625.PPSIR1_15265	4.803e-118	389.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
GNS2_k127_3677098_3	215803.DB30_4820	7.349e-51	193.0	2BT0K@1|root,32N4N@2|Bacteria,1Q3JT@1224|Proteobacteria,43419@68525|delta/epsilon subdivisions,2X4M2@28221|Deltaproteobacteria,2YZ8D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GNS2_k127_3677098_1	204669.Acid345_1271	2.683e-142	490.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
GNS2_k127_3677098_0	204669.Acid345_1270	5.783e-276	857.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GNS2_k127_3688347_0	926549.KI421517_gene1084	2.406e-109	365.0	28JXC@1|root,2Z8EX@2|Bacteria,4NF7D@976|Bacteroidetes,47M9Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3688347_1	243231.GSU0942	2.106e-74	261.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GNS2_k127_3688347_2	1123288.SOV_2c11530	4.086e-60	228.0	COG1807@1|root,COG1807@2|Bacteria,1UY16@1239|Firmicutes,4H35V@909932|Negativicutes	909932|Negativicutes	M	dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,SNARE_assoc
GNS2_k127_3688347_3	1340493.JNIF01000003_gene4349	7.038e-29	121.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
GNS2_k127_3688347_4	756499.Desde_2837	1.351e-06	52.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,2603K@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GNS2_k127_3688855_2	1123504.JQKD01000027_gene4143	0.0001577	49.0	COG0810@1|root,COG0810@2|Bacteria,1PWFZ@1224|Proteobacteria,2WC0I@28216|Betaproteobacteria,4AINM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
GNS2_k127_3688855_0	234267.Acid_5307	0.0	1352.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria	57723|Acidobacteria	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,E1_dh,OxoGdeHyase_C,Transket_pyr
GNS2_k127_3688855_1	1499967.BAYZ01000009_gene5328	4.929e-06	52.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
GNS2_k127_3730368_2	234267.Acid_7393	9.419e-108	367.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
GNS2_k127_3730368_5	575540.Isop_3342	4.179e-79	269.0	COG1704@1|root,COG1704@2|Bacteria,2IZBC@203682|Planctomycetes	203682|Planctomycetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
GNS2_k127_3730368_0	886293.Sinac_6493	1.866e-169	557.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GNS2_k127_3730368_1	1379270.AUXF01000004_gene3294	1.804e-115	405.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GNS2_k127_3730368_8	267608.RSc3099	7.386e-08	65.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2VSHI@28216|Betaproteobacteria,1K79N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,DUF4437
GNS2_k127_3730368_6	682795.AciX8_0041	1.683e-43	164.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_3730368_9	1122971.BAME01000107_gene5991	2.947e-05	55.0	COG1443@1|root,COG1443@2|Bacteria,4PJZY@976|Bacteroidetes,2FXBS@200643|Bacteroidia	976|Bacteroidetes	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GNS2_k127_3730368_7	448385.sce4710	3.495e-37	147.0	COG0494@1|root,COG0494@2|Bacteria,1QXXS@1224|Proteobacteria,43C8Y@68525|delta/epsilon subdivisions,2X7JB@28221|Deltaproteobacteria,2YVVN@29|Myxococcales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GNS2_k127_3730368_4	290397.Adeh_2049	7.237e-90	314.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,2YVBJ@29|Myxococcales	28221|Deltaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
GNS2_k127_3730368_3	246197.MXAN_1581	4.719e-91	313.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GNS2_k127_3746649_6	555088.DealDRAFT_2351	6.865e-15	89.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,42JW7@68298|Syntrophomonadaceae	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
GNS2_k127_3746649_1	314345.SPV1_07951	3.174e-154	507.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria	1224|Proteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GNS2_k127_3746649_3	880072.Desac_0158	8.589e-70	260.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MQD3@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
GNS2_k127_3746649_2	278957.ABEA03000115_gene576	9.523e-96	352.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,3K756@414999|Opitutae	414999|Opitutae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GNS2_k127_3746649_0	880073.Calab_3530	1.508e-166	536.0	COG1004@1|root,COG1004@2|Bacteria,2NNYN@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GNS2_k127_3746649_4	1047013.AQSP01000023_gene933	5.631e-59	218.0	COG0438@1|root,COG0438@2|Bacteria,2NR3F@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_3746649_5	1382356.JQMP01000003_gene1927	3.914e-34	144.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_3749733_0	84531.JMTZ01000136_gene2443	3.829e-213	673.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales	1236|Gammaproteobacteria	O	peptidase	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
GNS2_k127_3766077_2	671143.DAMO_2251	3.419e-103	340.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GNS2_k127_3766077_0	880072.Desac_0419	1.747e-292	919.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MQZP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GNS2_k127_3766077_1	941639.BCO26_1892	4.137e-163	522.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GNS2_k127_3766077_3	1158318.ATXC01000001_gene1441	2.805e-87	292.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GNS2_k127_3766077_4	234267.Acid_2025	1.709e-72	260.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GNS2_k127_3766077_5	1282360.ABAC460_19855	5.606e-68	244.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,PPC,Peptidase_M10_C
GNS2_k127_3771872_4	379066.GAU_2457	1.498e-45	170.0	2A37A@1|root,30RNW@2|Bacteria,1ZUP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3771872_2	1379270.AUXF01000003_gene3469	1.323e-89	305.0	COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GNS2_k127_3771872_0	671143.DAMO_1997	1.526e-221	694.0	COG0538@1|root,COG0538@2|Bacteria,2NS4M@2323|unclassified Bacteria	2|Bacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
GNS2_k127_3771872_6	1231190.NA8A_13245	6.913e-14	85.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2UGKQ@28211|Alphaproteobacteria,43M5D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
GNS2_k127_3771872_1	1173028.ANKO01000030_gene3287	3.522e-169	559.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GNS2_k127_3771872_7	56780.SYN_01247	5.117e-07	56.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3771872_3	211165.AJLN01000104_gene6576	3.204e-86	321.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_3771872_5	748247.AZKH_3824	4.254e-23	110.0	COG0500@1|root,COG2226@2|Bacteria,1REVA@1224|Proteobacteria,2VMI7@28216|Betaproteobacteria,2KVP6@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_3863677_1	59374.Fisuc_0589	2.978e-08	64.0	COG0457@1|root,COG0457@2|Bacteria	59374.Fisuc_0589|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3863677_0	204669.Acid345_2431	6.081e-31	129.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_3879776_0	204669.Acid345_1679	1.294e-75	265.0	COG0531@1|root,COG0531@2|Bacteria,3Y6AZ@57723|Acidobacteria,2JME9@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GNS2_k127_3879776_2	204669.Acid345_3237	3.981e-36	153.0	2EQP8@1|root,33I96@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3879776_3	204669.Acid345_3238	3.427e-33	130.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	MA20_26500	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GNS2_k127_3879776_1	234267.Acid_0799	1e-48	190.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GNS2_k127_3879776_4	314231.FP2506_15994	2.858e-14	81.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,2UM11@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GNS2_k127_3909334_9	439235.Dalk_3378	1.93e-06	57.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
GNS2_k127_3909334_1	671143.DAMO_0319	5.29e-99	352.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GNS2_k127_3909334_5	234267.Acid_5841	9.235e-66	241.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GNS2_k127_3909334_7	234267.Acid_7212	8.536e-30	127.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3909334_3	340.xcc-b100_0398	3.157e-83	289.0	COG2267@1|root,COG2267@2|Bacteria,1NHT1@1224|Proteobacteria	1224|Proteobacteria	I	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GNS2_k127_3909334_8	240015.ACP_2579	3.032e-25	113.0	COG3468@1|root,COG3468@2|Bacteria,3Y4BG@57723|Acidobacteria,2JJ56@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3909334_2	671143.DAMO_0664	1.157e-87	310.0	COG1521@1|root,COG1521@2|Bacteria,2NP3Z@2323|unclassified Bacteria	2|Bacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
GNS2_k127_3909334_6	404589.Anae109_1479	1.756e-39	162.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
GNS2_k127_3909334_4	1089553.Tph_c26610	1.052e-75	269.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,42F8G@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
GNS2_k127_3909334_0	1125863.JAFN01000001_gene800	0.0	1025.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GNS2_k127_3909334_11	1232410.KI421413_gene927	0.0006577	50.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,43UPW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GNS2_k127_3913856_2	448385.sce0621	2.845e-31	132.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,SBP_bac_10,Thioredoxin
GNS2_k127_3913856_1	927677.ALVU02000001_gene1177	2.479e-63	251.0	COG1361@1|root,COG2304@1|root,COG4870@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG4870@2|Bacteria,1G2M0@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GNS2_k127_3913856_0	1453500.AT05_08550	2.052e-81	310.0	COG1572@1|root,COG2911@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,4NIU0@976|Bacteroidetes,1HXV1@117743|Flavobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3945364_2	1120973.AQXL01000097_gene902	9.548e-87	300.0	COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HA93@91061|Bacilli,278J8@186823|Alicyclobacillaceae	91061|Bacilli	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
GNS2_k127_3945364_1	1047013.AQSP01000123_gene1522	6.768e-118	406.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GNS2_k127_3945364_4	234267.Acid_1770	2.094e-41	173.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
GNS2_k127_3945364_0	357808.RoseRS_3857	5.553e-205	655.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	32061|Chloroflexia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GNS2_k127_3945364_3	1278073.MYSTI_01846	3.383e-50	186.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GNS2_k127_3970637_4	1385517.N800_00445	4.715e-37	148.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1PH1W@1224|Proteobacteria,1RRYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,P_proprotein,Reprolysin_3,Reprolysin_4
GNS2_k127_3970637_2	596152.DesU5LDRAFT_2631	3.21e-44	184.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_3970637_6	644282.Deba_3244	1.811e-07	64.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
GNS2_k127_3970637_7	1385521.N803_10965	0.0001022	49.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_3970637_5	1385521.N803_10960	4.162e-11	69.0	COG1848@1|root,COG1848@2|Bacteria,2IR37@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	PIN
GNS2_k127_3970637_1	378806.STAUR_3239	2.735e-75	262.0	COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GNS2_k127_3970637_0	314230.DSM3645_18936	1.594e-94	331.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
GNS2_k127_3990003_0	1163407.UU7_05269	7.922e-90	303.0	COG1349@1|root,COG1349@2|Bacteria,1MUJT@1224|Proteobacteria,1SZXU@1236|Gammaproteobacteria,1X6YG@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GNS2_k127_3990311_1	469383.Cwoe_4933	1.37e-16	94.0	COG3320@1|root,COG3320@2|Bacteria,2I9YC@201174|Actinobacteria	201174|Actinobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
GNS2_k127_3990311_0	240015.ACP_1519	1.419e-199	636.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GNS2_k127_4002140_1	1122602.ATXP01000004_gene1917	2.122e-09	69.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria,1W81H@1268|Micrococcaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
GNS2_k127_4002140_2	926566.Terro_3666	1.024e-05	58.0	2F5TK@1|root,33YCF@2|Bacteria,3Y7TG@57723|Acidobacteria,2JMXH@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4002140_0	756067.MicvaDRAFT_0373	9.557e-17	94.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H6XA@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
GNS2_k127_4014226_1	748280.NH8B_2180	3.354e-113	369.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria	28216|Betaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GNS2_k127_4014226_0	1183438.GKIL_1930	6.608e-272	841.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria	1117|Cyanobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GNS2_k127_4014226_2	485916.Dtox_3828	1.589e-99	337.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,249F8@186801|Clostridia,264CT@186807|Peptococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
GNS2_k127_4049696_2	1292035.H476_3201	0.0009216	52.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIK@186804|Peptostreptococcaceae	186801|Clostridia	O	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GNS2_k127_4049696_1	572477.Alvin_1496	1.148e-13	84.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria,1WWFU@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
GNS2_k127_4049696_0	246197.MXAN_5122	2.637e-73	275.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GNS2_k127_4059795_3	1267535.KB906767_gene3160	1.756e-92	312.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
GNS2_k127_4059795_16	1280947.HY30_06735	4.381e-23	113.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,43XZ4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
GNS2_k127_4059795_18	338963.Pcar_1930	3.482e-18	93.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria,43VGK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GNS2_k127_4059795_2	215803.DB30_8153	1.023e-134	454.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2YY2C@29|Myxococcales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GNS2_k127_4059795_11	483219.LILAB_25490	5.588e-38	164.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GNS2_k127_4059795_14	1267533.KB906736_gene1122	4.288e-28	124.0	2E9H4@1|root,333Q5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4059795_12	1408473.JHXO01000007_gene748	5.434e-34	137.0	2E69N@1|root,330XJ@2|Bacteria,4NYHG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4059795_8	1267535.KB906767_gene3770	2.055e-64	229.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GNS2_k127_4059795_13	706587.Desti_3193	4.209e-29	123.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
GNS2_k127_4059795_20	316274.Haur_4405	3.03e-07	57.0	2DREH@1|root,33BDY@2|Bacteria,2G9NT@200795|Chloroflexi,377SC@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4059795_4	472759.Nhal_1764	3.566e-76	263.0	COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,1S376@1236|Gammaproteobacteria,1X1QH@135613|Chromatiales	135613|Chromatiales	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
GNS2_k127_4059795_9	1267533.KB906733_gene3426	9.423e-62	218.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria,2JN3W@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_4059795_10	246197.MXAN_3242	9.311e-44	178.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
GNS2_k127_4059795_7	1121920.AUAU01000001_gene2169	1.117e-67	237.0	2919Q@1|root,32TZW@2|Bacteria,3Y5IU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4059795_0	379066.GAU_2797	8.402e-309	960.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GNS2_k127_4059795_17	234267.Acid_7166	8.146e-20	97.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GNS2_k127_4059795_1	861299.J421_0438	9.315e-250	796.0	COG3968@1|root,COG3968@2|Bacteria,1ZSPJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
GNS2_k127_4059795_5	671143.DAMO_0700	4.674e-70	254.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	fixC	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
GNS2_k127_4059795_15	1267535.KB906767_gene1058	1.782e-24	113.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
GNS2_k127_4059795_6	1306406.ASHX01000002_gene5227	6.33e-68	245.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria	201174|Actinobacteria	Q	synthase	pks11	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GNS2_k127_4068959_6	404589.Anae109_3113	2.825e-37	144.0	COG1942@1|root,COG1942@2|Bacteria,1RHA5@1224|Proteobacteria,431G6@68525|delta/epsilon subdivisions,2WWH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
GNS2_k127_4068959_5	1379698.RBG1_1C00001G0743	2.362e-39	152.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
GNS2_k127_4068959_0	1183438.GKIL_3422	1.226e-156	506.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_4068959_1	338969.Rfer_0358	4.832e-101	349.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GNS2_k127_4068959_2	682795.AciX8_1632	8.151e-91	340.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria,2JIUS@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GNS2_k127_4068959_8	748247.AZKH_1460	3.088e-08	60.0	COG4691@1|root,COG4691@2|Bacteria,1NAMF@1224|Proteobacteria,2VWEK@28216|Betaproteobacteria,2KZ9Q@206389|Rhodocyclales	206389|Rhodocyclales	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
GNS2_k127_4068959_4	1187851.A33M_2653	2.369e-41	156.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2UAIV@28211|Alphaproteobacteria,3FEJG@34008|Rhodovulum	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
GNS2_k127_4068959_7	472759.Nhal_3311	8.451e-30	125.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GNS2_k127_406913_17	748247.AZKH_4123	0.0003641	43.0	COG3668@1|root,COG3668@2|Bacteria,1PUJD@1224|Proteobacteria,2WAUE@28216|Betaproteobacteria,2KZHN@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
GNS2_k127_406913_9	1499967.BAYZ01000005_gene5436	1.158e-40	173.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
GNS2_k127_406913_5	1449350.OCH239_17360	1.087e-86	297.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GNS2_k127_406913_8	401526.TcarDRAFT_2648	1.825e-48	196.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,4H592@909932|Negativicutes	909932|Negativicutes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_406913_3	383372.Rcas_0760	4.189e-119	399.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,377Y9@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_406913_16	935567.JAES01000002_gene684	1.051e-06	61.0	2E37T@1|root,32Y7G@2|Bacteria,1NKGS@1224|Proteobacteria,1T65R@1236|Gammaproteobacteria,1X8HF@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
GNS2_k127_406913_11	706587.Desti_4616	2.783e-33	138.0	COG2881@1|root,COG2881@2|Bacteria,1N6EP@1224|Proteobacteria,42U9Y@68525|delta/epsilon subdivisions,2WQGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1,zinc_ribbon_4
GNS2_k127_406913_13	671143.DAMO_0811	4.15e-19	93.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GNS2_k127_406913_0	290397.Adeh_4188	7.716e-181	579.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GNS2_k127_406913_12	330214.NIDE3048	1.222e-21	105.0	COG3216@1|root,COG3216@2|Bacteria,3J1DC@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
GNS2_k127_406913_6	243231.GSU3194	3.517e-59	218.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GNS2_k127_406913_14	682795.AciX8_0399	2.803e-12	71.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
GNS2_k127_406913_2	1121468.AUBR01000015_gene2254	1.977e-136	470.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
GNS2_k127_406913_4	880072.Desac_2305	1.552e-107	359.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MQ4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
GNS2_k127_406913_10	204669.Acid345_0715	1.292e-36	143.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GNS2_k127_406913_15	1469245.JFBG01000058_gene2365	3.203e-10	70.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
GNS2_k127_406913_7	760568.Desku_0639	2.526e-50	199.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,260V8@186807|Peptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GNS2_k127_406913_1	880073.Calab_3708	1.678e-136	441.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GNS2_k127_407798_0	706587.Desti_2026	6.975e-207	678.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GNS2_k127_407798_1	1123256.KB907929_gene3320	5.514e-99	364.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1X3K3@135614|Xanthomonadales	135614|Xanthomonadales	M	Arabinose 5-phosphate isomerase	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
GNS2_k127_407798_3	1123368.AUIS01000022_gene1049	8.333e-38	162.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,2NCVK@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
GNS2_k127_407798_2	644282.Deba_1300	7.544e-47	184.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
GNS2_k127_40820_2	1449126.JQKL01000006_gene781	4.844e-15	76.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,248BK@186801|Clostridia	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GNS2_k127_40820_4	1121380.JNIW01000027_gene3149	1.646e-11	69.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	pvuIIC	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GNS2_k127_40820_0	1449350.OCH239_10065	3.077e-133	449.0	COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,4KNK3@93682|Roseivivax	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SnoaL_2
GNS2_k127_40820_3	682795.AciX8_0336	1.796e-14	87.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19693	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Reg_prop
GNS2_k127_40820_1	1198114.AciX9_1464	8.126e-26	125.0	COG2304@1|root,COG2304@2|Bacteria,3Y5S3@57723|Acidobacteria	57723|Acidobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
GNS2_k127_4086063_0	192952.MM_2213	2.705e-77	295.0	arCOG07826@1|root,arCOG07826@2157|Archaea,2XXK4@28890|Euryarchaeota	28890|Euryarchaeota	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
GNS2_k127_4086063_1	1396418.BATQ01000186_gene2146	2.035e-49	185.0	COG2227@1|root,COG2227@2|Bacteria,46VSV@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF1698)	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
GNS2_k127_4086063_2	1121033.AUCF01000011_gene1751	4.02e-24	112.0	COG0463@1|root,COG0500@1|root,COG4424@1|root,COG0463@2|Bacteria,COG2226@2|Bacteria,COG4424@2|Bacteria,1MXQB@1224|Proteobacteria,2TSY1@28211|Alphaproteobacteria,2JZR6@204441|Rhodospirillales	204441|Rhodospirillales	MQ	Glycosyltransferase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_92
GNS2_k127_4086063_3	399739.Pmen_4281	0.0002926	46.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1YEET@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	pslH	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GNS2_k127_4086250_13	1267535.KB906767_gene1775	2.262e-53	193.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050,Stig1,ZU5
GNS2_k127_4086250_2	204669.Acid345_4761	6.723e-165	533.0	COG0312@1|root,COG0312@2|Bacteria,3Y2TY@57723|Acidobacteria,2JI8B@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GNS2_k127_4086250_3	234267.Acid_0372	1.279e-145	473.0	COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria	57723|Acidobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
GNS2_k127_4086250_5	330214.NIDE1515	1.025e-136	449.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GNS2_k127_4086250_19	29495.EA26_18010	2.73e-32	139.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales	135623|Vibrionales	S	permease	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GNS2_k127_4086250_26	404589.Anae109_3529	6.031e-18	98.0	2CA5X@1|root,33BSQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4086250_16	291985.CCSI01000006_gene1168	5.314e-36	139.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2U9EX@28211|Alphaproteobacteria,2K64Z@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GNS2_k127_4086250_1	234267.Acid_1536	9.135e-228	745.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GNS2_k127_4086250_9	1121468.AUBR01000058_gene875	9.961e-89	305.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,24ETR@186801|Clostridia,42FP9@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GNS2_k127_4086250_17	1234664.AMRO01000050_gene454	3.469e-35	146.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1WFBZ@129337|Geobacillus	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
GNS2_k127_4086250_12	330214.NIDE3554	2.957e-59	214.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GNS2_k127_4086250_18	1211114.ALIP01000140_gene2317	1.018e-33	130.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,1ST3I@1236|Gammaproteobacteria,1X8AD@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4086250_11	269798.CHU_3113	5.929e-63	236.0	295WE@1|root,2ZT7B@2|Bacteria,4NXBS@976|Bacteroidetes,47VZ0@768503|Cytophagia	976|Bacteroidetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
GNS2_k127_4086250_20	1121373.KB903663_gene1067	2.053e-31	128.0	2DS4P@1|root,33EH8@2|Bacteria,4PPZ4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4086250_10	326427.Cagg_0110	1.434e-85	298.0	COG0189@1|root,COG0189@2|Bacteria,2G864@200795|Chloroflexi,374WA@32061|Chloroflexia	32061|Chloroflexia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4086250_0	1121920.AUAU01000027_gene1498	3.203e-294	916.0	COG3590@1|root,COG3590@2|Bacteria,3Y2FY@57723|Acidobacteria	57723|Acidobacteria	O	peptidase	-	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
GNS2_k127_4086250_7	497964.CfE428DRAFT_5240	1.791e-116	385.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GNS2_k127_4086250_21	1121406.JAEX01000006_gene2155	8.498e-31	136.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,43B5Q@68525|delta/epsilon subdivisions,2X6J9@28221|Deltaproteobacteria,2MH3Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GNS2_k127_4086250_14	414684.RC1_3186	1.318e-52	201.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria,2JYYF@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_4086250_4	240015.ACP_3048	8.759e-145	466.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GNS2_k127_4086250_6	867903.ThesuDRAFT_01574	2.457e-128	427.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GNS2_k127_4086250_27	1232410.KI421426_gene1413	2.678e-05	49.0	2DGEV@1|root,2ZVPG@2|Bacteria,1QZ5A@1224|Proteobacteria,43CFW@68525|delta/epsilon subdivisions,2X7QX@28221|Deltaproteobacteria,43ST3@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4086250_15	234267.Acid_0321	3.707e-38	145.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
GNS2_k127_4086250_22	234267.Acid_0322	6.029e-28	115.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GNS2_k127_4086250_24	234267.Acid_0323	1.254e-18	91.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GNS2_k127_4086250_23	234267.Acid_0324	6.71e-19	94.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GNS2_k127_4086250_8	671143.DAMO_0390	5.168e-114	379.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GNS2_k127_4130733_0	269800.Tfu_1392	3.748e-05	50.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4EIHD@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
GNS2_k127_4138124_0	713586.KB900536_gene2395	1.723e-143	461.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
GNS2_k127_4138124_2	240292.Ava_1800	8.051e-96	320.0	COG1028@1|root,COG1028@2|Bacteria,1GDEA@1117|Cyanobacteria,1HRGV@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GNS2_k127_4138124_1	945713.IALB_0461	9.207e-109	362.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GNS2_k127_4174665_0	484019.THA_155	4.042e-205	651.0	COG1884@1|root,COG1884@2|Bacteria,2GBZM@200918|Thermotogae	200918|Thermotogae	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GNS2_k127_4174665_1	1123508.JH636445_gene6627	3.881e-180	573.0	COG1511@1|root,COG2770@1|root,COG1511@2|Bacteria,COG2770@2|Bacteria,2J4WR@203682|Planctomycetes	203682|Planctomycetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4177907_0	880073.Calab_0624	4.055e-138	451.0	COG0282@1|root,COG0282@2|Bacteria,2NNXT@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
GNS2_k127_4177907_5	1232410.KI421421_gene3586	0.0009394	52.0	COG1934@1|root,COG1934@2|Bacteria,1RM28@1224|Proteobacteria,42V9N@68525|delta/epsilon subdivisions,2WRB1@28221|Deltaproteobacteria,43V6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
GNS2_k127_4177907_2	269799.Gmet_1282	5.703e-97	323.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,43T7P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
GNS2_k127_4177907_1	56780.SYN_00945	2.705e-123	410.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2MQBH@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GNS2_k127_4177907_4	671143.DAMO_1191	1.101e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
GNS2_k127_4177907_3	243231.GSU1885	1.563e-91	312.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,43TVV@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
GNS2_k127_4188350_0	518766.Rmar_1441	2.767e-92	332.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_4188350_1	518766.Rmar_1440	3.962e-85	295.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
GNS2_k127_419472_4	1121918.ARWE01000001_gene2220	1.79e-05	53.0	COG0745@1|root,COG0745@2|Bacteria,1QZ5N@1224|Proteobacteria,4307W@68525|delta/epsilon subdivisions,2X7RC@28221|Deltaproteobacteria,43UV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
GNS2_k127_419472_3	204669.Acid345_0631	9.231e-22	106.0	COG2905@1|root,COG2905@2|Bacteria,3Y5NG@57723|Acidobacteria,2JN0N@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GNS2_k127_419472_2	1122139.KB907876_gene2430	9.612e-27	118.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XH6W@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	-	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GNS2_k127_419472_1	234267.Acid_6506	3.191e-48	186.0	COG3503@1|root,COG3503@2|Bacteria,3Y73K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GNS2_k127_419472_0	404589.Anae109_0303	8.714e-84	295.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
GNS2_k127_420314_4	1382359.JIAL01000001_gene1923	5.878e-75	266.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
GNS2_k127_420314_5	1280952.HJA_01545	9.256e-68	258.0	COG0793@1|root,COG0793@2|Bacteria,1R7I0@1224|Proteobacteria,2U0JI@28211|Alphaproteobacteria,43XH0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Peptidase family S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
GNS2_k127_420314_6	1121428.DESHY_80096___1	3.219e-39	169.0	COG0613@1|root,COG0613@2|Bacteria,1VINF@1239|Firmicutes,24SJB@186801|Clostridia	186801|Clostridia	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
GNS2_k127_420314_0	240015.ACP_2455	1.718e-193	614.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GNS2_k127_420314_1	289376.THEYE_A0112	2.407e-178	566.0	COG0192@1|root,COG0192@2|Bacteria,3J0A4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GNS2_k127_420314_3	292459.STH1821	1.004e-79	301.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GNS2_k127_420314_2	502025.Hoch_2444	1.248e-143	474.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GNS2_k127_420314_7	1382359.JIAL01000001_gene2110	1.394e-14	76.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria,2JJS9@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
GNS2_k127_420314_9	1158604.I591_01033	1.04e-08	65.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,4AZSF@81852|Enterococcaceae	91061|Bacilli	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GNS2_k127_4212053_3	1121015.N789_08450	1.4e-27	116.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4212053_1	1173028.ANKO01000250_gene2345	5.385e-88	299.0	COG4783@1|root,COG4783@2|Bacteria,1G084@1117|Cyanobacteria,1HAD1@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GNS2_k127_4212053_2	671143.DAMO_3042	6.819e-74	258.0	COG0177@1|root,COG0177@2|Bacteria,2NQYE@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF2400)	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF2400,EndIII_4Fe-2S,HhH-GPD
GNS2_k127_4212053_0	330214.NIDE3977	8.063e-141	457.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GNS2_k127_4212053_4	573370.DMR_32610	1.401e-17	89.0	COG1555@1|root,COG1555@2|Bacteria,1N7MI@1224|Proteobacteria	1224|Proteobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
GNS2_k127_4212053_5	1907.SGLAU_08540	1.093e-14	86.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
GNS2_k127_4212053_6	502025.Hoch_3979	1.312e-10	62.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2YXN1@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GNS2_k127_4282993_3	1173024.KI912148_gene3242	4.001e-53	193.0	COG0135@1|root,COG0135@2|Bacteria,1G8QG@1117|Cyanobacteria	1117|Cyanobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GNS2_k127_4282993_1	861299.J421_0666	1.702e-165	528.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4282993_5	1075090.GOAMR_70_00180	1.375e-09	70.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4GEX6@85026|Gordoniaceae	201174|Actinobacteria	H	ThiS family	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GNS2_k127_4282993_0	234267.Acid_4432	8.493e-272	848.0	COG1132@1|root,COG1132@2|Bacteria,3Y6S4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter transmembrane	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GNS2_k127_4282993_2	794903.OPIT5_28655	1.084e-108	359.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
GNS2_k127_4282993_4	269800.Tfu_2199	3.601e-10	61.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4EGZW@85012|Streptosporangiales	201174|Actinobacteria	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
GNS2_k127_4294573_6	745014.OMB55_00003540	2.863e-32	133.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
GNS2_k127_4294573_7	879212.DespoDRAFT_00177	2.518e-21	101.0	COG0484@1|root,COG0484@2|Bacteria,1N19U@1224|Proteobacteria,42TX7@68525|delta/epsilon subdivisions,2WQMA@28221|Deltaproteobacteria,2MNA8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
GNS2_k127_4294573_4	1125863.JAFN01000001_gene1127	4.73e-56	201.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,43ADJ@68525|delta/epsilon subdivisions,2WMPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0920	SIS_2
GNS2_k127_4294573_2	330214.NIDE4314	1.842e-105	361.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4294573_5	265729.GS18_0200595	5.866e-55	204.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GNS2_k127_4294573_0	1242864.D187_006139	0.0	1215.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GNS2_k127_4294573_1	1340493.JNIF01000003_gene4049	1.277e-123	409.0	COG1473@1|root,COG1473@2|Bacteria,3Y40E@57723|Acidobacteria	2|Bacteria	S	Peptidase dimerisation domain	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_4294573_3	869210.Marky_0344	1.201e-61	220.0	COG1043@1|root,COG1043@2|Bacteria,1WJYZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Acyl- acyl-carrier-protein --UDP-N-acetylglucosamine O-acyltransferase	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
GNS2_k127_4305763_0	266117.Rxyl_0021	2.377e-59	220.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GNS2_k127_4305763_1	448385.sce6976	5.493e-17	85.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
GNS2_k127_4326258_1	330084.JNYZ01000017_gene5263	1.104e-13	79.0	COG0110@1|root,COG0110@2|Bacteria,2HP0M@201174|Actinobacteria,4E7I9@85010|Pseudonocardiales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	maa	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GNS2_k127_4326258_0	1128421.JAGA01000003_gene3091	5.817e-45	188.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_4326258_2	1111479.AXAR01000001_gene252	4.212e-07	61.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,1VI49@1239|Firmicutes	1239|Firmicutes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_4335077_1	1128421.JAGA01000001_gene2269	1.151e-70	246.0	COG1028@1|root,COG1028@2|Bacteria,2NQB4@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GNS2_k127_4335077_3	867903.ThesuDRAFT_01224	1.323e-43	163.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GNS2_k127_4335077_5	489825.LYNGBM3L_35820	4.076e-27	116.0	COG0346@1|root,COG0346@2|Bacteria,1G65U@1117|Cyanobacteria,1HBJC@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GNS2_k127_4335077_7	1205680.CAKO01000026_gene4554	7.879e-13	72.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,2JTV5@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
GNS2_k127_4335077_0	1254432.SCE1572_24235	4.669e-190	608.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria,42S3P@68525|delta/epsilon subdivisions,2WNCE@28221|Deltaproteobacteria,2YUQB@29|Myxococcales	28221|Deltaproteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
GNS2_k127_4335077_2	1121920.AUAU01000004_gene742	1.505e-66	229.0	COG3832@1|root,COG3832@2|Bacteria,3Y57B@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GNS2_k127_4335077_4	215803.DB30_6257	3.242e-39	149.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,4382M@68525|delta/epsilon subdivisions,2X3CP@28221|Deltaproteobacteria,2YVFV@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GNS2_k127_4335077_8	573370.DMR_10280	1.274e-05	51.0	COG1344@1|root,COG2931@1|root,COG1344@2|Bacteria,COG2931@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WIK0@28221|Deltaproteobacteria,2M86I@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
GNS2_k127_4351592_1	234267.Acid_6711	1.144e-43	169.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
GNS2_k127_4351592_2	443144.GM21_1097	1.708e-32	134.0	COG0746@1|root,COG0746@2|Bacteria,1PJ8E@1224|Proteobacteria,42VYH@68525|delta/epsilon subdivisions,2WRBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GNS2_k127_4351592_0	365044.Pnap_3584	7.245e-48	179.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,2WEXX@28216|Betaproteobacteria,4AHP4@80864|Comamonadaceae	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GNS2_k127_4351592_3	211165.AJLN01000116_gene3556	2.412e-30	130.0	COG3871@1|root,COG3871@2|Bacteria,1GBSH@1117|Cyanobacteria,1JIRB@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
GNS2_k127_4362046_0	671143.DAMO_2633	9.36e-113	378.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	ytfL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699,ko:K06189	-	-	-	-	ko00000,ko02000,ko02042	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21,TerC
GNS2_k127_4362046_1	234267.Acid_0912	4.202e-70	264.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria	57723|Acidobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GNS2_k127_4380167_0	1121441.AUCX01000021_gene690	1.452e-153	502.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GNS2_k127_4380167_1	335543.Sfum_1456	1.795e-100	350.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
GNS2_k127_4397475_1	293826.Amet_2327	0.0002234	50.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,36JB7@31979|Clostridiaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
GNS2_k127_4397475_0	1047013.AQSP01000139_gene2398	6.572e-56	211.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	lytC_1	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
GNS2_k127_440962_0	204669.Acid345_0770	1.659e-93	336.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
GNS2_k127_440962_1	1183438.GKIL_0470	3.473e-86	315.0	COG0451@1|root,COG0451@2|Bacteria,1GBK7@1117|Cyanobacteria	1117|Cyanobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GNS2_k127_441648_0	7213.XP_004528550.1	2.44e-89	306.0	COG1043@1|root,2QRGY@2759|Eukaryota,3A2QI@33154|Opisthokonta,3CAAK@33208|Metazoa,3DRFN@33213|Bilateria,422DR@6656|Arthropoda,3SQHR@50557|Insecta	33208|Metazoa	M	Udp N-acetylglucosamine O-acyltransferase; Domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,FabA,Hexapep
GNS2_k127_441648_2	1267533.KB906734_gene4091	1.539e-69	259.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
GNS2_k127_441648_1	330214.NIDE3038	4.242e-88	304.0	COG0673@1|root,COG0673@2|Bacteria,3J0M7@40117|Nitrospirae	40117|Nitrospirae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GNS2_k127_441648_3	1123060.JONP01000008_gene4512	2.168e-07	62.0	COG0810@1|root,COG0810@2|Bacteria,1R8XC@1224|Proteobacteria	1224|Proteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
GNS2_k127_4431055_3	882.DVU_1909	1.657e-06	51.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2MCER@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GNS2_k127_4431055_0	926550.CLDAP_02490	3.854e-41	167.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142,Glyco_hydro_18
GNS2_k127_4431055_1	1123073.KB899242_gene1683	2.023e-39	165.0	2EP1Q@1|root,33GNJ@2|Bacteria,1NKYB@1224|Proteobacteria,1SH1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DIE2/ALG10 family	-	-	-	-	-	-	-	-	-	-	-	-	DIE2_ALG10
GNS2_k127_4431055_2	357808.RoseRS_2707	6.147e-08	61.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_4437254_1	1499967.BAYZ01000026_gene1569	4.479e-133	428.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GNS2_k127_4437254_5	926569.ANT_14540	3.436e-31	134.0	COG0115@1|root,COG0115@2|Bacteria,2G8EE@200795|Chloroflexi	200795|Chloroflexi	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GNS2_k127_4437254_3	351160.RCIX32	1.626e-40	152.0	COG0720@1|root,arCOG02172@2157|Archaea,2XZ5K@28890|Euryarchaeota,2N9WF@224756|Methanomicrobia	224756|Methanomicrobia	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GNS2_k127_4437254_7	63737.Npun_R3135	2.394e-24	110.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GNS2_k127_4437254_6	1122929.KB908215_gene729	1.804e-28	121.0	COG4564@1|root,COG4564@2|Bacteria,1RJP6@1224|Proteobacteria,2VFTF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
GNS2_k127_4437254_8	653733.Selin_0088	5.619e-17	92.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	nueM	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
GNS2_k127_4437254_0	317655.Sala_1467	8.639e-216	691.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2K1RR@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GNS2_k127_4437254_4	497964.CfE428DRAFT_6273	1.012e-33	143.0	2CGDR@1|root,336BW@2|Bacteria,46WG2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4437254_2	1267535.KB906767_gene5001	1.17e-95	340.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GNS2_k127_4440677_2	1219049.SP5_034_00880	2.265e-62	223.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2TW0V@28211|Alphaproteobacteria,2KCP4@204457|Sphingomonadales	204457|Sphingomonadales	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GNS2_k127_4440677_0	1382359.JIAL01000001_gene3006	6.503e-127	415.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GNS2_k127_4440677_1	404589.Anae109_0187	1.653e-67	244.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0017	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
GNS2_k127_4440677_3	10029.XP_007634511.1	3.108e-16	87.0	COG3000@1|root,KOG0539@2759|Eukaryota,38DTY@33154|Opisthokonta,3BIM1@33208|Metazoa,3CRXQ@33213|Bilateria,485VR@7711|Chordata,495JF@7742|Vertebrata,3J5V1@40674|Mammalia,35DN4@314146|Euarchontoglires,4Q24Y@9989|Rodentia	33208|Metazoa	I	Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids	FA2H	GO:0001949,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006807,GO:0007009,GO:0007272,GO:0007275,GO:0007399,GO:0007417,GO:0007422,GO:0008150,GO:0008152,GO:0008366,GO:0008544,GO:0008610,GO:0009058,GO:0009888,GO:0009913,GO:0009987,GO:0010001,GO:0010256,GO:0012505,GO:0014003,GO:0014037,GO:0014044,GO:0016020,GO:0016043,GO:0016491,GO:0019752,GO:0021782,GO:0022008,GO:0022010,GO:0022011,GO:0030148,GO:0030154,GO:0030258,GO:0030855,GO:0031984,GO:0032286,GO:0032287,GO:0032291,GO:0032292,GO:0032501,GO:0032502,GO:0032787,GO:0042063,GO:0042127,GO:0042175,GO:0042552,GO:0042634,GO:0043217,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043588,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0048468,GO:0048513,GO:0048709,GO:0048731,GO:0048732,GO:0048733,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051239,GO:0052722,GO:0055114,GO:0060429,GO:0061024,GO:0065007,GO:0071704,GO:0071840,GO:0080132,GO:0098827,GO:1901564,GO:1901566,GO:1901576	1.14.18.6	ko:K19703	-	-	-	-	ko00000,ko01000	-	-	-	Cyt-b5,FA_hydroxylase
GNS2_k127_4440677_4	357808.RoseRS_2422	8.087e-05	49.0	COG0500@1|root,COG2226@2|Bacteria,2GBT7@200795|Chloroflexi,375QW@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_4454411_5	383372.Rcas_3354	5.535e-20	100.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_4454411_3	243231.GSU1896	3.298e-78	270.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
GNS2_k127_4454411_0	289377.HL41_00285	1.972e-211	670.0	COG0504@1|root,COG0504@2|Bacteria,2GHMU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
GNS2_k127_4454411_2	398767.Glov_2172	7.79e-92	332.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
GNS2_k127_4454411_6	383372.Rcas_0467	4.019e-15	89.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi,376AH@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4454411_4	1210884.HG799465_gene11528	4.411e-22	106.0	COG0500@1|root,COG2226@2|Bacteria,2J1F4@203682|Planctomycetes	203682|Planctomycetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_4454411_1	573370.DMR_23340	9.968e-96	327.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2M99V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
GNS2_k127_4455189_6	497964.CfE428DRAFT_6274	8.951e-19	98.0	COG3503@1|root,COG3503@2|Bacteria,46VZH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
GNS2_k127_4455189_7	867903.ThesuDRAFT_01255	3.363e-16	80.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia	186801|Clostridia	O	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GNS2_k127_4455189_5	1499967.BAYZ01000177_gene5710	4.415e-30	124.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GNS2_k127_4455189_3	525904.Tter_0359	2.024e-55	211.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
GNS2_k127_4455189_4	404589.Anae109_1952	8.735e-34	145.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
GNS2_k127_4455189_0	1382359.JIAL01000001_gene1269	3.828e-110	366.0	COG1131@1|root,COG1131@2|Bacteria,3Y6FZ@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_4455189_2	1382359.JIAL01000001_gene1268	1.221e-65	233.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GNS2_k127_4455189_1	1125863.JAFN01000001_gene2144	1.461e-68	246.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	transport system involved in gliding motility, auxiliary	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
GNS2_k127_4534939_2	1144275.COCOR_07464	3.35e-52	194.0	COG0526@1|root,COG0526@2|Bacteria,1NH1D@1224|Proteobacteria,42XJ2@68525|delta/epsilon subdivisions,2X5GC@28221|Deltaproteobacteria,2YUZX@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
GNS2_k127_4534939_1	204669.Acid345_4600	1.132e-111	388.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_4534939_0	706587.Desti_4874	1.303e-154	525.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MQ68@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GNS2_k127_4534939_4	1382359.JIAL01000001_gene753	3.276e-15	87.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4534939_3	1123073.KB899243_gene666	2.492e-42	158.0	2CX7C@1|root,32T1D@2|Bacteria,1N2N3@1224|Proteobacteria,1S4YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4534939_5	358823.DF19_22055	0.0002915	49.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Sigma70_r4_2
GNS2_k127_4535641_2	231434.JQJH01000009_gene1115	4.768e-19	90.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,3N9PF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
GNS2_k127_4535641_0	861299.J421_2667	8.163e-127	426.0	COG0022@1|root,COG0022@2|Bacteria,1ZTA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GNS2_k127_4535641_1	671143.DAMO_1598	4.03e-111	370.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GNS2_k127_4550855_3	1382359.JIAL01000001_gene2034	9.801e-85	304.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GNS2_k127_4550855_7	338969.Rfer_0485	5.238e-28	119.0	COG4319@1|root,COG4319@2|Bacteria,1RGSM@1224|Proteobacteria,2VYTU@28216|Betaproteobacteria,4AG0E@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GNS2_k127_4550855_6	1210884.HG799466_gene12471	1.207e-32	133.0	COG0406@1|root,COG0406@2|Bacteria,2J315@203682|Planctomycetes	203682|Planctomycetes	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4550855_9	234267.Acid_3442	4.036e-09	68.0	2E0D8@1|root,32W02@2|Bacteria,3Y5V4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4550855_2	211165.AJLN01000050_gene5268	9.618e-112	389.0	COG0665@1|root,COG0665@2|Bacteria,1G4DH@1117|Cyanobacteria	1117|Cyanobacteria	C	Sarcosine oxidase	solA	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2
GNS2_k127_4550855_1	1279017.AQYJ01000028_gene2405	1.596e-126	419.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
GNS2_k127_4550855_5	1078020.KEK_00910	3.699e-42	169.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria,23AH8@1762|Mycobacteriaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GNS2_k127_4550855_4	1379270.AUXF01000001_gene2039	2.948e-57	209.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_4550855_0	1382359.JIAL01000001_gene1458	1.259e-196	629.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
GNS2_k127_4552316_4	745310.G432_10875	3.788e-08	63.0	COG1287@1|root,COG1287@2|Bacteria,1R184@1224|Proteobacteria,2TYYC@28211|Alphaproteobacteria,2KEPT@204457|Sphingomonadales	204457|Sphingomonadales	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_4552316_2	439235.Dalk_2057	4.834e-48	177.0	COG0041@1|root,COG0151@1|root,COG0041@2|Bacteria,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
GNS2_k127_4552316_0	1047013.AQSP01000099_gene1500	8.731e-138	451.0	COG0151@1|root,COG0151@2|Bacteria,2NP0B@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the GARS family	purD	-	6.3.2.6,6.3.4.13,6.3.5.3	ko:K01945,ko:K01952,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04463,R04591	RC00010,RC00064,RC00090,RC00162,RC00166,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
GNS2_k127_4552316_3	589924.Ferp_2390	6.341e-11	74.0	COG0500@1|root,arCOG01773@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GNS2_k127_4552316_5	485913.Krac_4773	9.883e-08	65.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_4552316_1	370438.PTH_0066	1.709e-73	259.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,260K0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GNS2_k127_4555999_2	1192034.CAP_3990	1.463e-140	452.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_4555999_0	502025.Hoch_2603	1.223e-186	607.0	COG0167@1|root,COG0479@1|root,COG0167@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.1.1,1.3.1.2,1.97.1.9	ko:K00207,ko:K12527,ko:K17723	ko00240,ko00410,ko00450,ko00770,ko00983,ko01100,map00240,map00410,map00450,map00770,map00983,map01100	M00046	R00977,R00978,R01414,R01415,R07229,R08226,R11026	RC00072,RC00123,RC02245,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	ATC_hydrolase,CCG,DHO_dh,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_20,Fer4_8,Pyr_redox_2
GNS2_k127_4555999_1	1089553.Tph_c27030	2.29e-153	500.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,2482F@186801|Clostridia,42FYT@68295|Thermoanaerobacterales	186801|Clostridia	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
GNS2_k127_4555999_3	1396141.BATP01000059_gene2564	6.751e-135	436.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GNS2_k127_4555999_4	196162.Noca_1629	5.482e-107	362.0	COG0402@1|root,COG0402@2|Bacteria,2ISY0@201174|Actinobacteria	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_4574955_2	635013.TherJR_0520	1.24e-108	367.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GNS2_k127_4574955_0	521674.Plim_4031	4.954e-158	530.0	COG0433@1|root,COG0433@2|Bacteria,2IY71@203682|Planctomycetes	203682|Planctomycetes	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,PDDEXK_1
GNS2_k127_4574955_3	234267.Acid_1239	4.052e-57	215.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,Response_reg,SpoIIE
GNS2_k127_4574955_1	1144275.COCOR_06542	4.558e-138	454.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_4591959_0	204669.Acid345_4675	0.0	1633.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GNS2_k127_4608873_7	290397.Adeh_2856	1.906e-27	129.0	COG0558@1|root,COG0558@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
GNS2_k127_4608873_5	1191523.MROS_1266	1.591e-50	204.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GNS2_k127_4608873_1	335543.Sfum_2925	2.112e-157	508.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_4608873_2	1278073.MYSTI_05459	1.096e-71	254.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
GNS2_k127_4608873_0	1173025.GEI7407_3011	2.695e-244	775.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria,1H8Q4@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
GNS2_k127_4608873_6	404589.Anae109_1700	7.997e-49	190.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
GNS2_k127_4608873_4	1307436.PBF_08223	3.607e-59	226.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GNS2_k127_4608873_3	1047013.AQSP01000131_gene1841	1.497e-67	256.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_4631115_3	1121381.JNIV01000003_gene3427	6.709e-07	55.0	COG2244@1|root,COG2244@2|Bacteria,1WIZQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
GNS2_k127_4631115_1	1254432.SCE1572_09230	8.917e-88	318.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YXCH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_4631115_0	671143.DAMO_0414	3.479e-125	419.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
GNS2_k127_4631115_2	204669.Acid345_0162	3.422e-77	263.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria,2JHMH@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GNS2_k127_4656478_1	1125863.JAFN01000001_gene1165	4.591e-54	194.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,42QNE@68525|delta/epsilon subdivisions,2WMT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	CT_C_D,LamB_YcsF
GNS2_k127_4656478_2	1227487.C474_03855	1.071e-16	86.0	arCOG11838@1|root,arCOG11838@2157|Archaea,2Y03W@28890|Euryarchaeota,23XVJ@183963|Halobacteria	183963|Halobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
GNS2_k127_4656478_0	768671.ThimaDRAFT_1458	2.035e-70	252.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1WX7E@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	VWA_2
GNS2_k127_4656478_3	1122222.AXWR01000023_gene1521	7.151e-10	59.0	COG0777@1|root,COG0777@2|Bacteria,1WIB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GNS2_k127_4656738_1	589865.DaAHT2_0464	4.807e-84	302.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
GNS2_k127_4656738_3	1254432.SCE1572_16555	5.887e-49	183.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
GNS2_k127_4656738_4	215803.DB30_7213	6.241e-45	173.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,43C29@68525|delta/epsilon subdivisions,2X7CU@28221|Deltaproteobacteria,2YV3W@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GNS2_k127_4656738_0	338963.Pcar_2038	2.211e-200	647.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GNS2_k127_4656738_5	1162668.LFE_1682	3.273e-13	74.0	COG2924@1|root,COG2924@2|Bacteria,3J1CU@40117|Nitrospirae	40117|Nitrospirae	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
GNS2_k127_4656738_2	871968.DESME_05950	6.01e-65	228.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,2600W@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GNS2_k127_4695100_1	204669.Acid345_1305	6.063e-147	480.0	COG1009@1|root,COG1009@2|Bacteria,3Y2VS@57723|Acidobacteria,2JIG7@204432|Acidobacteriia	204432|Acidobacteriia	CP	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GNS2_k127_4695100_0	243231.GSU0350	4.136e-155	525.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GNS2_k127_4695100_2	671143.DAMO_2690	4.47e-109	391.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GNS2_k127_4695100_3	639030.JHVA01000001_gene2440	1.467e-93	312.0	COG1794@1|root,COG1794@2|Bacteria,3Y5EC@57723|Acidobacteria,2JJRS@204432|Acidobacteriia	204432|Acidobacteriia	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
GNS2_k127_4695100_5	1485544.JQKP01000001_gene1266	1.247e-14	81.0	COG3678@1|root,COG3678@2|Bacteria,1NBYM@1224|Proteobacteria,2VXG9@28216|Betaproteobacteria	28216|Betaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
GNS2_k127_4695100_4	1123229.AUBC01000006_gene895	1.639e-92	310.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,3JRQF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_4758970_0	1144275.COCOR_02996	1.511e-43	165.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
GNS2_k127_4758970_1	1144275.COCOR_02994	5.488e-19	100.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,43DRS@68525|delta/epsilon subdivisions,2X8U4@28221|Deltaproteobacteria,2Z0DW@29|Myxococcales	28221|Deltaproteobacteria	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GNS2_k127_4758970_2	215803.DB30_1961	4.437e-11	76.0	COG0457@1|root,COG0457@2|Bacteria,1Q3GN@1224|Proteobacteria,43991@68525|delta/epsilon subdivisions,2X4GC@28221|Deltaproteobacteria,2YYYS@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
GNS2_k127_479522_1	1304885.AUEY01000096_gene2843	7.026e-47	175.0	COG0697@1|root,COG0697@2|Bacteria,1MX1Y@1224|Proteobacteria,42NTW@68525|delta/epsilon subdivisions,2WMEN@28221|Deltaproteobacteria,2MJQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GNS2_k127_479522_0	204669.Acid345_4634	7.273e-105	350.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria,2JHJZ@204432|Acidobacteriia	204432|Acidobacteriia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
GNS2_k127_4838345_1	448385.sce6976	1.716e-86	301.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
GNS2_k127_4838345_3	1121920.AUAU01000010_gene25	5.162e-43	181.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
GNS2_k127_4838345_0	309801.trd_A0275	4.395e-95	331.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
GNS2_k127_4838345_2	903818.KI912268_gene2829	3.792e-44	178.0	COG0784@1|root,COG1100@1|root,COG3852@1|root,COG0784@2|Bacteria,COG1100@2|Bacteria,COG3852@2|Bacteria,3Y9EH@57723|Acidobacteria	57723|Acidobacteria	T	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Ras,Response_reg
GNS2_k127_4974179_1	1502851.FG93_02367	3.244e-99	333.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2U22H@28211|Alphaproteobacteria,3JZZ8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GNS2_k127_4974179_0	290397.Adeh_3931	5.596e-117	389.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria	1224|Proteobacteria	E	PFAM homoserine dehydrogenase	metL	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
GNS2_k127_4974179_3	1121920.AUAU01000018_gene1775	5.473e-53	193.0	COG2318@1|root,COG2318@2|Bacteria,3Y4HW@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_4974179_2	1173020.Cha6605_4325	4.331e-75	267.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GNS2_k127_4986696_3	316067.Geob_3380	2.17e-38	158.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GNS2_k127_4986696_2	316067.Geob_3381	1.693e-68	265.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GNS2_k127_4986696_1	316067.Geob_3382	3.351e-80	296.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WKB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GNS2_k127_4986696_0	316067.Geob_3384	5.427e-135	468.0	COG0840@1|root,COG1511@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
GNS2_k127_4986696_4	177439.DP3100	1.629e-12	78.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions,2WJW5@28221|Deltaproteobacteria,2MJYV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
GNS2_k127_5003082_0	1121013.P873_12785	7.748e-262	818.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1SZTS@1236|Gammaproteobacteria,1X4EA@135614|Xanthomonadales	135614|Xanthomonadales	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GNS2_k127_5003082_1	1499967.BAYZ01000009_gene5321	2.704e-58	215.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
GNS2_k127_5014952_1	1116472.MGMO_94c00200	1.562e-122	420.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XE5W@135618|Methylococcales	1236|Gammaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	GO:0000271,GO:0003674,GO:0003824,GO:0003979,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_2287	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GNS2_k127_5014952_0	1210884.HG799467_gene13162	5.489e-148	478.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GNS2_k127_5014952_3	96561.Dole_2627	2.741e-33	145.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
GNS2_k127_5014952_2	1210884.HG799467_gene13163	7.255e-80	279.0	COG1215@1|root,COG1215@2|Bacteria,2J0E2@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_5026216_0	402777.KB235903_gene788	0.0	1727.0	COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1GHDJ@1117|Cyanobacteria,1H8KY@1150|Oscillatoriales	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
GNS2_k127_5026216_1	1487953.JMKF01000005_gene617	1.449e-91	343.0	COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
GNS2_k127_5026216_2	1192034.CAP_5014	0.0001612	50.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,439XQ@68525|delta/epsilon subdivisions,2X1V0@28221|Deltaproteobacteria,2YZ8J@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,Response_reg
GNS2_k127_5026615_3	1125863.JAFN01000001_gene2653	6.658e-52	207.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
GNS2_k127_5026615_7	9733.XP_004262728.1	0.0009153	44.0	KOG0032@1|root,KOG0613@1|root,KOG0032@2759|Eukaryota,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,483G3@7711|Chordata,48XF8@7742|Vertebrata,3JD64@40674|Mammalia,4JARD@91561|Cetartiodactyla	33208|Metazoa	T	Immunoglobulin C-2 Type	SPEG	GO:0001701,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007507,GO:0007517,GO:0008150,GO:0008152,GO:0008285,GO:0009790,GO:0009792,GO:0009888,GO:0009987,GO:0014706,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0030016,GO:0030017,GO:0030018,GO:0030154,GO:0031674,GO:0032501,GO:0032502,GO:0035051,GO:0036211,GO:0042127,GO:0042692,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051146,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0060537,GO:0060541,GO:0061061,GO:0065007,GO:0071704,GO:0072358,GO:0072359,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564	2.7.11.1	ko:K08809	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	I-set,Pkinase,SPEG_u2,fn3
GNS2_k127_5026615_6	391619.PGA1_c08500	7.838e-05	54.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,34FSC@302485|Phaeobacter	28211|Alphaproteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5
GNS2_k127_5026615_4	1248916.ANFY01000007_gene2186	6.093e-08	64.0	COG5126@1|root,COG5126@2|Bacteria,1NAM6@1224|Proteobacteria,2UH6E@28211|Alphaproteobacteria,2K75T@204457|Sphingomonadales	204457|Sphingomonadales	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
GNS2_k127_5026615_1	383372.Rcas_1801	1.471e-99	340.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
GNS2_k127_5026615_0	234267.Acid_3926	1.774e-129	444.0	COG2170@1|root,COG2170@2|Bacteria,3Y6P8@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
GNS2_k127_5026615_5	439235.Dalk_4189	4.913e-05	56.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_5026615_2	399795.CtesDRAFT_PD3622	8.254e-62	226.0	2E2KP@1|root,32XPY@2|Bacteria,1N5X4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5034940_4	867903.ThesuDRAFT_01263	1.256e-18	94.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_5034940_2	518766.Rmar_2195	6.344e-106	350.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1FIV9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
GNS2_k127_5034940_0	706587.Desti_2041	2.908e-237	766.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GNS2_k127_5034940_3	1121920.AUAU01000007_gene484	1.328e-25	116.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GNS2_k127_5034940_1	1382306.JNIM01000001_gene1966	5.742e-177	567.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GNS2_k127_5037064_12	204669.Acid345_2825	7.965e-39	155.0	COG0627@1|root,COG0627@2|Bacteria,3Y8UN@57723|Acidobacteria	57723|Acidobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GNS2_k127_5037064_6	1163409.UUA_10501	7.776e-100	346.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
GNS2_k127_5037064_11	234267.Acid_3571	1.701e-56	224.0	COG0558@1|root,COG0558@2|Bacteria,3Y4PW@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
GNS2_k127_5037064_8	1379698.RBG1_1C00001G1665	3.53e-70	252.0	COG0845@1|root,COG0845@2|Bacteria,2NQ2U@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GNS2_k127_5037064_13	1192034.CAP_7999	1.826e-18	96.0	2AS5D@1|root,32BXX@2|Bacteria,1QADV@1224|Proteobacteria,4350N@68525|delta/epsilon subdivisions,2X93Y@28221|Deltaproteobacteria,2Z1S2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5037064_1	1192034.CAP_7998	1.6e-154	498.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX63@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
GNS2_k127_5037064_3	1192034.CAP_7997	3.585e-135	457.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX5U@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
GNS2_k127_5037064_10	945713.IALB_2676	1.769e-63	226.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
GNS2_k127_5037064_5	1123229.AUBC01000031_gene272	1.482e-110	374.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,3JQY5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GNS2_k127_5037064_0	1121920.AUAU01000006_gene304	4.75e-176	584.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
GNS2_k127_5037064_9	378806.STAUR_0277	1.387e-68	249.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GNS2_k127_5037064_7	443143.GM18_1245	9.714e-90	318.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GNS2_k127_5037064_4	330214.NIDE0474	4.487e-132	430.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GNS2_k127_5037064_2	330214.NIDE0473	1.96e-140	455.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
GNS2_k127_5037064_14	1144275.COCOR_05175	2.935e-15	87.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
GNS2_k127_5063568_1	1163617.SCD_n01782	1.383e-68	247.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GNS2_k127_5063568_0	1380391.JIAS01000014_gene2275	2.238e-107	356.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,2JPS7@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GNS2_k127_508681_1	1121451.DESAM_22263	2.939e-05	48.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2MCER@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GNS2_k127_508681_0	861299.J421_4062	9.029e-76	271.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_5100282_7	204669.Acid345_4380	5.968e-39	160.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
GNS2_k127_5100282_5	1329516.JPST01000007_gene1507	5.792e-54	197.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,27B00@186824|Thermoactinomycetaceae	91061|Bacilli	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GNS2_k127_5100282_9	903818.KI912268_gene2144	4.803e-34	145.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria	57723|Acidobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GNS2_k127_5100282_4	311424.DhcVS_280	1.844e-79	280.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi,34CK3@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GNS2_k127_5100282_10	1423814.HMPREF0549_1742	1.566e-22	109.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GNS2_k127_5100282_12	459349.CLOAM1466	1.841e-13	72.0	COG1837@1|root,COG1837@2|Bacteria,2NPUP@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GNS2_k127_5100282_11	765420.OSCT_2871	3.711e-22	111.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi,377I8@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GNS2_k127_5100282_1	234267.Acid_2573	2.552e-143	476.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GNS2_k127_5100282_8	1278073.MYSTI_02245	3.958e-37	146.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GNS2_k127_5100282_0	1123376.AUIU01000007_gene1178	1.725e-167	537.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
GNS2_k127_5100282_6	446465.Bfae_00070	2.76e-52	198.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4FCSV@85020|Dermabacteraceae	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
GNS2_k127_5100282_2	1121468.AUBR01000026_gene2918	1.58e-94	323.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GNS2_k127_5100282_3	1382359.JIAL01000001_gene2789	2.705e-83	302.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GNS2_k127_5100282_13	1121918.ARWE01000001_gene2061	1.283e-10	66.0	COG2018@1|root,COG2018@2|Bacteria,1N5TV@1224|Proteobacteria,42UGD@68525|delta/epsilon subdivisions,2WQXP@28221|Deltaproteobacteria,43SPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GNS2_k127_5100282_14	351160.RCIX2537	1.162e-08	65.0	COG0457@1|root,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GNS2_k127_5104293_2	1254432.SCE1572_35695	9.672e-153	490.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,4306C@68525|delta/epsilon subdivisions,2WVFZ@28221|Deltaproteobacteria,2YU0U@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
GNS2_k127_5104293_0	1254432.SCE1572_33190	2.168e-219	692.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YU8Z@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	rbsA	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10542,ko:K10545,ko:K10548	ko02010,map02010	M00189,M00212,M00214,M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
GNS2_k127_5104293_1	1254432.SCE1572_33185	1.362e-158	532.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,430ZH@68525|delta/epsilon subdivisions,2X9DE@28221|Deltaproteobacteria,2YUXW@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
GNS2_k127_5104293_5	452637.Oter_2465	1.448e-72	255.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,46VST@74201|Verrucomicrobia,3K7DE@414999|Opitutae	74201|Verrucomicrobia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hycG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
GNS2_k127_5104293_3	452637.Oter_2464	9.539e-145	486.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,46TQW@74201|Verrucomicrobia,3K7GA@414999|Opitutae	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hycE	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
GNS2_k127_5104293_4	452637.Oter_2463	5.133e-109	370.0	COG0651@1|root,COG0651@2|Bacteria,46UK3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
GNS2_k127_5104293_6	452637.Oter_2462	2.681e-43	166.0	COG4237@1|root,COG4237@2|Bacteria,46W3G@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
GNS2_k127_5179844_2	656519.Halsa_1356	3.935e-06	60.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,25413@186801|Clostridia,3WC1R@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM TonB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
GNS2_k127_5179844_0	671143.DAMO_0568	3.471e-226	726.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GNS2_k127_5179844_1	1382359.JIAL01000001_gene1457	5.659e-09	65.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
GNS2_k127_5183970_2	3055.EDO97312	9.099e-13	74.0	COG2374@1|root,2QV0U@2759|Eukaryota,382YS@33090|Viridiplantae	33090|Viridiplantae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5183970_1	290397.Adeh_2417	1.023e-84	303.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,42W09@68525|delta/epsilon subdivisions,2WRB8@28221|Deltaproteobacteria,2YVVC@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
GNS2_k127_5183970_0	290397.Adeh_2418	1.019e-136	445.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42PT6@68525|delta/epsilon subdivisions,2WK6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_5189096_6	262724.TT_C0932	1.217e-08	62.0	COG0120@1|root,COG0120@2|Bacteria,1WIR4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
GNS2_k127_5189096_0	479434.Sthe_2436	1.52e-164	546.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GNS2_k127_5189096_1	1382356.JQMP01000003_gene1988	7.97e-119	393.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GNS2_k127_5189096_4	1121381.JNIV01000029_gene1895	2.893e-49	192.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GNS2_k127_5189096_3	378806.STAUR_7040	1.304e-54	201.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GNS2_k127_5189096_2	357808.RoseRS_2110	1.678e-102	347.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi,374S3@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GNS2_k127_5189096_5	1382306.JNIM01000001_gene1159	1.408e-11	70.0	COG1977@1|root,COG1977@2|Bacteria,2G9JN@200795|Chloroflexi	200795|Chloroflexi	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
GNS2_k127_5189406_0	1123368.AUIS01000006_gene566	5.496e-128	431.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
GNS2_k127_5189406_4	1047013.AQSP01000091_gene645	1.196e-63	246.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
GNS2_k127_5189406_1	867903.ThesuDRAFT_00244	6.153e-123	421.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WCSG@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
GNS2_k127_5189406_8	518766.Rmar_0961	2.41e-38	162.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GNS2_k127_5189406_2	760568.Desku_2556	4.166e-89	309.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GNS2_k127_5189406_7	1121438.JNJA01000014_gene469	2.994e-49	188.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2M99I@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GNS2_k127_5189406_6	234267.Acid_4993	2.436e-56	203.0	COG0461@1|root,COG0461@2|Bacteria	2|Bacteria	F	orotate phosphoribosyltransferase activity	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GNS2_k127_5189406_5	1267535.KB906767_gene2285	2.356e-62	223.0	COG0463@1|root,COG0463@2|Bacteria,3Y34G@57723|Acidobacteria,2JIGQ@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_5189406_3	1125863.JAFN01000001_gene535	4.861e-75	275.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_5190223_6	926550.CLDAP_10880	1.15e-26	117.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi	200795|Chloroflexi	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GNS2_k127_5190223_5	880073.Calab_1192	1.396e-30	126.0	COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria	2|Bacteria	I	Phosphatidylglycerophosphatase A	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
GNS2_k127_5190223_3	1267535.KB906767_gene1017	1.787e-90	327.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GNS2_k127_5190223_7	926569.ANT_08670	3.293e-23	115.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GNS2_k127_5190223_4	696369.KI912183_gene1279	7.391e-35	151.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,261ZE@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GNS2_k127_5190223_2	1379270.AUXF01000006_gene284	2.376e-91	322.0	COG0240@1|root,COG0240@2|Bacteria,1ZTFK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GNS2_k127_5190223_1	1121920.AUAU01000011_gene183	1.636e-91	322.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,3Y85P@57723|Acidobacteria	57723|Acidobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
GNS2_k127_5190223_0	204669.Acid345_3335	1.563e-94	334.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
GNS2_k127_5195829_1	694429.Pyrfu_1633	1.2e-97	343.0	COG1167@1|root,arCOG00492@2157|Archaea,2XPUJ@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM Aminotransferase class I and II	agt	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GNS2_k127_5195829_7	1340493.JNIF01000003_gene3955	1.246e-41	158.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
GNS2_k127_5195829_5	867903.ThesuDRAFT_02149	4.478e-70	243.0	COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,24SBR@186801|Clostridia	186801|Clostridia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GNS2_k127_5195829_8	869210.Marky_1964	1.428e-40	157.0	COG1845@1|root,COG1845@2|Bacteria,1WK7G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GNS2_k127_5195829_0	644966.Tmar_0405	1.045e-214	682.0	COG0843@1|root,COG0843@2|Bacteria,1V0TJ@1239|Firmicutes,25DDI@186801|Clostridia	186801|Clostridia	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GNS2_k127_5195829_6	869210.Marky_1966	6.221e-63	225.0	COG1622@1|root,COG1622@2|Bacteria,1WJ34@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG1622 Heme copper-type cytochrome quinol oxidase subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
GNS2_k127_5195829_3	1304883.KI912532_gene1606	5.44e-87	301.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,2KUCZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GNS2_k127_5195829_4	765911.Thivi_0930	1.267e-82	284.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_5195829_2	522306.CAP2UW1_4287	1.209e-88	319.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_5205827_15	204669.Acid345_1974	1.49e-23	104.0	COG0718@1|root,COG0718@2|Bacteria,3Y5CB@57723|Acidobacteria,2JJRM@204432|Acidobacteriia	204432|Acidobacteriia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
GNS2_k127_5205827_1	706587.Desti_2208	9.303e-183	582.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5205827_19	861299.J421_1992	5.015e-09	70.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5205827_0	1267534.KB906755_gene4695	2.02e-316	1000.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria,2JK9M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_5205827_8	68170.KL590510_gene7215	1.036e-86	291.0	COG3647@1|root,COG3647@2|Bacteria,2IATE@201174|Actinobacteria,4E3YF@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
GNS2_k127_5205827_11	234267.Acid_3167	1.397e-76	261.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria	57723|Acidobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
GNS2_k127_5205827_13	443144.GM21_4049	4.607e-63	220.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GNS2_k127_5205827_6	404589.Anae109_3758	1.778e-95	315.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
GNS2_k127_5205827_16	1340493.JNIF01000003_gene4326	3.99e-17	85.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GNS2_k127_5205827_14	1207058.L53_04075	1.066e-40	163.0	28JQH@1|root,2Z9GD@2|Bacteria,1R2MF@1224|Proteobacteria,2TZS1@28211|Alphaproteobacteria,44163@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5205827_5	84531.JMTZ01000054_gene1524	7.85e-108	377.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1X3BA@135614|Xanthomonadales	135614|Xanthomonadales	H	Outer membrane receptor proteins mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
GNS2_k127_5205827_3	234267.Acid_0825	2.318e-110	369.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5205827_2	234267.Acid_0826	1.446e-133	432.0	COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria	57723|Acidobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
GNS2_k127_5205827_4	234267.Acid_0827	1.052e-108	359.0	COG1108@1|root,COG1108@2|Bacteria,3Y93X@57723|Acidobacteria	57723|Acidobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
GNS2_k127_5205827_12	398720.MED217_08240	3.508e-75	289.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_5205827_7	1121920.AUAU01000005_gene994	1.9e-91	313.0	COG0579@1|root,COG0579@2|Bacteria,3Y6NN@57723|Acidobacteria	57723|Acidobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
GNS2_k127_5205827_9	319224.Sputcn32_3404	1.274e-85	292.0	COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,1S0XC@1236|Gammaproteobacteria,2QEJ4@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GNS2_k127_5205827_17	1101195.Meth11DRAFT_2192	1.493e-13	83.0	2BB2J@1|root,324IQ@2|Bacteria,1NVN6@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GNS2_k127_5205827_18	926566.Terro_0731	2.482e-09	66.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_5205827_10	204669.Acid345_3836	1.817e-77	267.0	COG2027@1|root,COG3653@1|root,COG2027@2|Bacteria,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GNS2_k127_5212626_8	696281.Desru_3258	4.721e-15	77.0	COG0431@1|root,COG0431@2|Bacteria,1V41C@1239|Firmicutes,25BUB@186801|Clostridia,2674C@186807|Peptococcaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
GNS2_k127_5212626_2	391625.PPSIR1_34113	2.216e-89	308.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
GNS2_k127_5212626_1	1123508.JH636446_gene6369	1.168e-152	516.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GNS2_k127_5212626_6	344747.PM8797T_18926	1.965e-23	113.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5212626_5	330214.NIDE3333	7.796e-40	162.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,3J0VE@40117|Nitrospirae	40117|Nitrospirae	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
GNS2_k127_5212626_7	1211115.ALIQ01000066_gene3459	2.925e-19	101.0	COG1524@1|root,COG1524@2|Bacteria,1PTI0@1224|Proteobacteria,2TUW7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GNS2_k127_5212626_3	991905.SL003B_3937	4.109e-55	200.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,4BPZ8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	3'-5' exonuclease	rnd1	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
GNS2_k127_5212626_10	1121434.AULY01000007_gene1598	0.0001885	54.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2M8HB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
GNS2_k127_5212626_0	290397.Adeh_0408	1.982e-225	719.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
GNS2_k127_5212626_4	448385.sce0049	1.034e-52	188.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_5219418_1	204669.Acid345_0678	1.162e-69	249.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yagE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GNS2_k127_5219418_0	926566.Terro_1277	5.169e-299	948.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria,2JKKF@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
GNS2_k127_5219418_2	1047013.AQSP01000131_gene1841	2.918e-07	57.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_5222758_0	1267535.KB906767_gene4009	4.121e-189	604.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria,2JHY2@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
GNS2_k127_5222758_1	204669.Acid345_3257	1.439e-168	538.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
GNS2_k127_525286_0	1121920.AUAU01000011_gene212	3.149e-157	503.0	COG2267@1|root,COG2267@2|Bacteria,3Y2IJ@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GNS2_k127_525286_2	357808.RoseRS_4474	4.752e-88	320.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP_C
GNS2_k127_525286_3	926560.KE387023_gene1389	5.101e-85	310.0	COG3842@1|root,COG3842@2|Bacteria,1WM7F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
GNS2_k127_525286_1	1499967.BAYZ01000009_gene5322	4.74e-127	425.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GNS2_k127_5260521_2	580340.Tlie_1825	4.512e-70	256.0	COG0110@1|root,COG0110@2|Bacteria,3TCJQ@508458|Synergistetes	508458|Synergistetes	S	transferase hexapeptide	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
GNS2_k127_5260521_0	1047013.AQSP01000144_gene776	5.386e-109	362.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
GNS2_k127_5260521_1	1121403.AUCV01000031_gene2831	5.996e-107	355.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42PZ9@68525|delta/epsilon subdivisions,2WM8K@28221|Deltaproteobacteria,2MIPB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_5317693_6	1198114.AciX9_3387	3.357e-10	66.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria,2JIGT@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_5317693_4	237368.SCABRO_00084	1.654e-23	114.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.2.1.82	ko:K18650	-	-	-	-	ko00000,ko01000	-	GH28	-	Esterase_phd,Lipase_GDSL_2
GNS2_k127_5317693_8	1501268.EW14_0730	1.656e-08	66.0	2B8TB@1|root,3223D@2|Bacteria,1GMYV@1117|Cyanobacteria,1MNGK@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5317693_5	710686.Mycsm_05272	1.436e-14	86.0	COG3011@1|root,COG3011@2|Bacteria,2GN4W@201174|Actinobacteria,23614@1762|Mycobacteriaceae	201174|Actinobacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
GNS2_k127_5317693_1	398720.MED217_09902	3.765e-29	128.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1HWTG@117743|Flavobacteriia,2XI66@283735|Leeuwenhoekiella	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_5317693_3	1210884.HG799466_gene12510	2.404e-24	115.0	COG3000@1|root,COG3000@2|Bacteria,2J0DV@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_5317693_0	1380390.JIAT01000013_gene124	6.326e-87	303.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GNS2_k127_5317693_9	313612.L8106_09571	0.0005321	52.0	COG3011@1|root,COG3011@2|Bacteria,1GBBP@1117|Cyanobacteria,1HDV0@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
GNS2_k127_5317693_7	1304872.JAGC01000003_gene3036	2.405e-09	70.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_5317693_2	290397.Adeh_3934	7.998e-25	117.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GNS2_k127_5344591_5	401053.AciPR4_3943	7.3e-26	109.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria,2JN1Z@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S18	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
GNS2_k127_5344591_7	880072.Desac_2605	2.042e-09	68.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
GNS2_k127_5344591_4	1382359.JIAL01000001_gene1373	6.013e-40	154.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GNS2_k127_5344591_6	1353529.M899_3031	6.905e-17	91.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2MTEE@213481|Bdellovibrionales,2WSJV@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GNS2_k127_5344591_1	635013.TherJR_2972	2.136e-149	486.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GNS2_k127_5344591_3	338963.Pcar_2234	8.211e-74	263.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,43TGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GNS2_k127_5344591_0	1232410.KI421412_gene157	1.979e-164	530.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,43S0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
GNS2_k127_5344591_2	204669.Acid345_0189	4.017e-110	365.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GNS2_k127_5344665_0	637389.Acaty_c1513	2.691e-56	206.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,2NBXP@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GNS2_k127_5344665_2	706587.Desti_2693	2.711e-33	134.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MS9I@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
GNS2_k127_5344665_1	439235.Dalk_0921	3.746e-38	150.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MHZN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GNS2_k127_5397264_8	1125863.JAFN01000001_gene1716	3.525e-15	77.0	COG0140@1|root,COG0140@2|Bacteria,1QXPJ@1224|Proteobacteria,42S79@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	phosphoribosyl-ATP diphosphatase activity	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
GNS2_k127_5397264_2	518766.Rmar_1042	1.27e-132	441.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1FIRE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GNS2_k127_5397264_3	644966.Tmar_1454	9.399e-96	332.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WCZN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GNS2_k127_5397264_5	502025.Hoch_3582	3.204e-61	239.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
GNS2_k127_5397264_0	243274.THEMA_04115	1.488e-142	488.0	COG0133@1|root,COG0133@2|Bacteria,2GEGC@200918|Thermotogae	200918|Thermotogae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_5397264_4	1267535.KB906767_gene284	1.2e-72	270.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GNS2_k127_5397264_7	243231.GSU1828	1.232e-19	101.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
GNS2_k127_5397264_1	234267.Acid_7885	9.633e-137	448.0	COG2876@1|root,COG2876@2|Bacteria,3Y2SV@57723|Acidobacteria	57723|Acidobacteria	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GNS2_k127_5416778_0	1379698.RBG1_1C00001G1459	5.137e-145	476.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_5416778_1	862751.SACTE_4577	2.898e-26	114.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GNS2_k127_5444252_1	641491.DND132_1187	1.116e-08	63.0	COG1572@1|root,COG1572@2|Bacteria,1PGI2@1224|Proteobacteria,4378M@68525|delta/epsilon subdivisions,2X2BD@28221|Deltaproteobacteria,2MFJP@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
GNS2_k127_5444252_0	1333507.AUTQ01000131_gene467	2.192e-47	184.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,2Q5DK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GNS2_k127_5472566_0	909663.KI867150_gene213	5.785e-96	356.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GNS2_k127_5472566_2	1688.BCUN_0698	5.178e-16	87.0	COG0366@1|root,COG3055@1|root,COG5492@1|root,COG0366@2|Bacteria,COG3055@2|Bacteria,COG5492@2|Bacteria,2GM4Q@201174|Actinobacteria,4CYYI@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CBM_20,CBM_25,SLH
GNS2_k127_5472566_1	1384054.N790_11430	1.135e-33	137.0	COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,1S9RI@1236|Gammaproteobacteria,1X7YA@135614|Xanthomonadales	135614|Xanthomonadales	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
GNS2_k127_548792_4	1279009.ADICEAN_03926	7.875e-05	48.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,47MQ3@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GNS2_k127_548792_1	696369.KI912183_gene1026	2.958e-22	108.0	COG0599@1|root,COG0599@2|Bacteria,1UWS5@1239|Firmicutes,24J92@186801|Clostridia,26232@186807|Peptococcaceae	186801|Clostridia	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GNS2_k127_548792_2	91464.S7335_2099	2.256e-21	110.0	COG4774@1|root,COG4774@2|Bacteria,1G2EF@1117|Cyanobacteria,1GZMW@1129|Synechococcus	1117|Cyanobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AMIN,Plug,TonB_dep_Rec
GNS2_k127_548792_0	330214.NIDE1392	1.376e-275	865.0	COG0046@1|root,COG0046@2|Bacteria,3J0TJ@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
GNS2_k127_548792_3	1137799.GZ78_21305	2.068e-05	48.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria,1XK56@135619|Oceanospirillales	135619|Oceanospirillales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_553093_0	401053.AciPR4_1343	2.449e-76	261.0	COG0766@1|root,COG0766@2|Bacteria,3Y2IC@57723|Acidobacteria,2JI7D@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GNS2_k127_553093_1	215803.DB30_7212	9.362e-75	273.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GNS2_k127_553093_4	396588.Tgr7_1677	6.192e-16	84.0	COG4446@1|root,COG4446@2|Bacteria,1NNQ9@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
GNS2_k127_553093_3	1123401.JHYQ01000045_gene3372	8.422e-43	159.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
GNS2_k127_553093_2	1163617.SCD_n01782	1.372e-71	256.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GNS2_k127_554339_0	1521187.JPIM01000035_gene3397	2.485e-103	356.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GNS2_k127_554339_1	1254432.SCE1572_25895	6.543e-87	312.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria,2Z3CW@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GNS2_k127_554339_2	1254432.SCE1572_25890	3.821e-60	220.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria,2YVAU@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GNS2_k127_5601434_0	861299.J421_1964	2.474e-203	664.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
GNS2_k127_5601434_1	1125863.JAFN01000001_gene278	9.431e-15	87.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,43AY8@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005,ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GNS2_k127_5601434_2	398767.Glov_0538	0.0005772	48.0	COG1538@1|root,COG1538@2|Bacteria,1R6VY@1224|Proteobacteria,430DM@68525|delta/epsilon subdivisions,2WWMP@28221|Deltaproteobacteria,43VIN@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
GNS2_k127_5617779_5	861299.J421_4428	7.717e-11	63.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GNS2_k127_5617779_7	1123373.ATXI01000030_gene291	0.0003797	52.0	COG3064@1|root,COG3064@2|Bacteria,2GH3G@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5617779_1	330214.NIDE1599	3.166e-102	341.0	COG0623@1|root,COG0623@2|Bacteria,3J11E@40117|Nitrospirae	40117|Nitrospirae	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GNS2_k127_5617779_4	1047013.AQSP01000138_gene1041	1.149e-60	239.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659	-	ko:K04744,ko:K09774,ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2,1.B.42.1	-	iAF987.Gmet_2474,iECO111_1330.ECO111_4695,iECSF_1327.ECSF_3725,iEcSMS35_1347.EcSMS35_4260	KdgM,OstA,OstA_2,OstA_C
GNS2_k127_5617779_0	357808.RoseRS_1611	4.126e-122	402.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GNS2_k127_5617779_2	1122919.KB905549_gene2055	7.116e-97	330.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,26S2Z@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GNS2_k127_5617779_3	3649.evm.model.supercontig_49.3	7.378e-72	267.0	COG0451@1|root,KOG1502@2759|Eukaryota,37JYY@33090|Viridiplantae,3G71H@35493|Streptophyta,3HP0I@3699|Brassicales	35493|Streptophyta	V	NmrA-like family	-	-	1.1.1.354	ko:K15891	ko00900,ko00909,ko01130,map00900,map00909,map01130	-	R10412	RC00649	ko00000,ko00001,ko01000	-	-	-	Epimerase
GNS2_k127_5617779_6	521674.Plim_0071	3.165e-09	68.0	COG0170@1|root,COG0170@2|Bacteria,2J1H5@203682|Planctomycetes	203682|Planctomycetes	I	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_566593_1	234267.Acid_2151	1.32e-76	278.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	2|Bacteria	S	PFAM LmbE family protein	mca	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	NPCBM_assoc,PIG-L
GNS2_k127_566593_0	246197.MXAN_2517	2.574e-77	268.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GNS2_k127_5711862_0	1324957.K933_00557	2.409e-47	191.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
GNS2_k127_5711862_1	378806.STAUR_5719	2.245e-15	88.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,43BTI@68525|delta/epsilon subdivisions,2X74F@28221|Deltaproteobacteria,2Z3FS@29|Myxococcales	28221|Deltaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
GNS2_k127_574381_2	1123405.AUMM01000003_gene568	1.341e-18	94.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,26PHC@186821|Sporolactobacillaceae	91061|Bacilli	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
GNS2_k127_574381_1	1267533.KB906737_gene1606	1.022e-23	117.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	204432|Acidobacteriia	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_574381_0	204669.Acid345_3271	3.357e-115	395.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GNS2_k127_5753337_1	1499967.BAYZ01000119_gene3214	5.133e-27	116.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
GNS2_k127_5753337_0	929562.Emtol_3207	9.516e-134	442.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,4NF3T@976|Bacteroidetes,47KQE@768503|Cytophagia	976|Bacteroidetes	I	3-oxoacid CoA-transferase, a subunit	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GNS2_k127_5805318_4	1385935.N836_19855	5.365e-64	244.0	COG0702@1|root,COG0702@2|Bacteria,1G1JM@1117|Cyanobacteria,1HHK6@1150|Oscillatoriales	1117|Cyanobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
GNS2_k127_5805318_0	404589.Anae109_4038	1.332e-159	511.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,438FV@68525|delta/epsilon subdivisions,2X3QT@28221|Deltaproteobacteria,2YWVJ@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
GNS2_k127_5805318_3	1313172.YM304_23330	1.75e-79	274.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CN0I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
GNS2_k127_5805318_5	869210.Marky_2141	3.398e-63	241.0	COG0506@1|root,COG0506@2|Bacteria,1WJB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GNS2_k127_5805318_1	411684.HPDFL43_14972	8.996e-84	296.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,43KPD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
GNS2_k127_5805318_9	204669.Acid345_1405	1.485e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,3Y7Q5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
GNS2_k127_5805318_10	671143.DAMO_1319	0.0002017	51.0	COG0457@1|root,COG3712@1|root,COG4773@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	FecR,Plug,STN,TPR_16,TPR_8,TonB_dep_Rec
GNS2_k127_5805318_6	1244083.CSUNSWCD_1352	2.892e-55	213.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42M5H@68525|delta/epsilon subdivisions,2YTMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
GNS2_k127_5805318_8	1297742.A176_05875	3.699e-14	72.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1N34Y@1224|Proteobacteria,42TV3@68525|delta/epsilon subdivisions,2WQ5Z@28221|Deltaproteobacteria,2YUQ5@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
GNS2_k127_5805318_2	234267.Acid_0081	8.245e-83	297.0	COG1409@1|root,COG1409@2|Bacteria,3Y6AF@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GNS2_k127_5805318_7	234267.Acid_0082	4.098e-19	96.0	2FE51@1|root,3464Y@2|Bacteria,3Y8E0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5805318_11	1267535.KB906767_gene561	0.0009726	42.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
GNS2_k127_5840227_1	1340493.JNIF01000004_gene473	1.048e-43	185.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5840227_0	448385.sce8781	1.108e-206	658.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YXCT@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GNS2_k127_5840227_2	246197.MXAN_3206	7.948e-22	110.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GNS2_k127_587939_0	861299.J421_3672	2.792e-113	379.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_587939_1	497964.CfE428DRAFT_0885	8.409e-49	189.0	2F2ZI@1|root,33VUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_587939_2	861299.J421_3670	9.58e-44	164.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
GNS2_k127_5882808_0	1047013.AQSP01000128_gene416	8.918e-91	312.0	COG1131@1|root,COG1131@2|Bacteria,2NQRI@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_5882808_1	1403819.BATR01000120_gene4243	4.655e-73	256.0	COG0627@1|root,COG0627@2|Bacteria,46UB3@74201|Verrucomicrobia,2IWI4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GNS2_k127_5882808_2	136993.KB900626_gene1049	3.162e-35	145.0	COG2755@1|root,COG2755@2|Bacteria,1RDZF@1224|Proteobacteria,2U7C2@28211|Alphaproteobacteria,36ZTF@31993|Methylocystaceae	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_5890668_1	1382359.JIAL01000001_gene2069	2.138e-224	703.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GNS2_k127_5890668_3	1340493.JNIF01000004_gene350	1.751e-84	288.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GNS2_k127_5890668_0	1340493.JNIF01000004_gene349	4.285e-228	715.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GNS2_k127_5890668_4	1121123.AUAO01000001_gene1217	8.239e-23	107.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2KGEU@204458|Caulobacterales	204458|Caulobacterales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GNS2_k127_5890668_2	867903.ThesuDRAFT_01739	1.531e-90	308.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3WCHC@538999|Clostridiales incertae sedis	186801|Clostridia	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GNS2_k127_5927139_2	1242864.D187_010394	1.663e-19	96.0	COG2905@1|root,COG2905@2|Bacteria,1R0B9@1224|Proteobacteria,43CTI@68525|delta/epsilon subdivisions,2X8MP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	cNMP_binding
GNS2_k127_5927139_0	391625.PPSIR1_32512	1.225e-142	462.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
GNS2_k127_5927139_1	1211114.ALIP01000111_gene1249	7.249e-78	267.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,1SFHY@1236|Gammaproteobacteria,1X50S@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
GNS2_k127_5947998_0	234267.Acid_7662	2.613e-153	502.0	COG0160@1|root,COG0160@2|Bacteria,3Y4EV@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.55	ko:K00823,ko:K15372	ko00250,ko00410,ko00430,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00430,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R01684	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_5947998_3	864702.OsccyDRAFT_0211	5.259e-16	92.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GNS2_k127_5947998_1	926564.KI911609_gene4316	8.5e-80	273.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
GNS2_k127_5947998_2	1121035.AUCH01000004_gene249	1.46e-18	89.0	COG2261@1|root,COG2261@2|Bacteria,1NE11@1224|Proteobacteria	1224|Proteobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GNS2_k127_5947998_4	525904.Tter_1129	1.514e-07	56.0	COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630
GNS2_k127_5959690_2	1232410.KI421428_gene1212	3.495e-19	94.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,43S9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GNS2_k127_5959690_1	518766.Rmar_1678	1.041e-24	109.0	COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,1FJCV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GNS2_k127_5959690_0	204669.Acid345_3014	1.215e-126	452.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GNS2_k127_5979683_2	316274.Haur_0845	1.969e-19	99.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GNS2_k127_5979683_0	1379698.RBG1_1C00001G0806	1.612e-105	349.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GNS2_k127_5979683_1	1125863.JAFN01000001_gene2446	1.549e-53	197.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GNS2_k127_6009901_1	234267.Acid_0599	1.548e-103	346.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GNS2_k127_6009901_2	574087.Acear_1020	4.443e-42	171.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WAJK@53433|Halanaerobiales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GNS2_k127_6009901_0	861299.J421_4478	5.492e-138	451.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GNS2_k127_6011123_2	404589.Anae109_0938	4.378e-71	244.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
GNS2_k127_6011123_0	1267533.KB906735_gene4863	2.715e-100	337.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria,2JHZ4@204432|Acidobacteriia	204432|Acidobacteriia	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
GNS2_k127_6011123_1	1210884.HG799465_gene11340	6.52e-80	272.0	COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GNS2_k127_602357_6	204669.Acid345_1461	1.402e-44	163.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GNS2_k127_602357_2	1125863.JAFN01000001_gene3329	2.686e-81	302.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
GNS2_k127_602357_8	991905.SL003B_3563	9.257e-19	99.0	COG4254@1|root,COG4254@2|Bacteria,1PPWK@1224|Proteobacteria,2TYY3@28211|Alphaproteobacteria,4BRH4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
GNS2_k127_602357_4	1232410.KI421413_gene960	9.706e-65	246.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GNS2_k127_602357_7	378806.STAUR_7589	6.451e-19	90.0	COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GNS2_k127_602357_5	269084.syc0760_d	7.42e-55	205.0	COG0142@1|root,COG0142@2|Bacteria,1G1H4@1117|Cyanobacteria,1GZHB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GNS2_k127_602357_1	1121472.AQWN01000002_gene2266	1.312e-115	383.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GNS2_k127_602357_3	338963.Pcar_1292	1.354e-65	229.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,43SE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
GNS2_k127_602357_0	667014.Thein_1915	1.545e-133	437.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GNS2_k127_602357_9	1123371.ATXH01000052_gene627	2.238e-11	65.0	2DTS4@1|root,33MFD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6040209_0	234267.Acid_2212	8.961e-203	638.0	COG2304@1|root,COG2304@2|Bacteria,3Y33Z@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase M64 N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
GNS2_k127_6040209_5	1267535.KB906767_gene3595	1.258e-42	178.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_6040209_2	1382356.JQMP01000001_gene812	1.133e-105	380.0	COG1294@1|root,COG1294@2|Bacteria,2G6IA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
GNS2_k127_6040209_1	886293.Sinac_4610	7.306e-167	535.0	COG1271@1|root,COG1271@2|Bacteria,2IXYC@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome bd-type quinol oxidase subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
GNS2_k127_6040209_4	358396.C445_20345	8.793e-51	201.0	COG0395@1|root,arCOG00159@2157|Archaea,2XWGD@28890|Euryarchaeota,23TSI@183963|Halobacteria	183963|Halobacteria	P	COG0395 ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GNS2_k127_6040209_3	358396.C445_20340	7.587e-71	249.0	COG1175@1|root,arCOG00157@2157|Archaea,2XW1I@28890|Euryarchaeota,23UPK@183963|Halobacteria	183963|Halobacteria	P	COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GNS2_k127_6054164_3	1123242.JH636436_gene366	3.869e-16	78.0	COG5649@1|root,COG5649@2|Bacteria,2IYNG@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GNS2_k127_6054164_1	504472.Slin_6199	2.869e-43	172.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47XD5@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GNS2_k127_6054164_0	1267533.KB906741_gene569	2.452e-69	249.0	COG0262@1|root,COG0262@2|Bacteria,3Y4XB@57723|Acidobacteria,2JMZH@204432|Acidobacteriia	204432|Acidobacteriia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GNS2_k127_6054164_2	266117.Rxyl_0910	1.313e-34	136.0	COG1683@1|root,COG1683@2|Bacteria,2IJAV@201174|Actinobacteria	201174|Actinobacteria	F	Protein of unknown function (DUF523)	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF523,PNP_UDP_1
GNS2_k127_6105708_9	1042877.GQS_01000	2.714e-14	83.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_6105708_4	697282.Mettu_0012	4.449e-75	253.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,1SBIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GNS2_k127_6105708_5	886293.Sinac_4302	2.291e-68	243.0	COG3266@1|root,COG4655@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,2IZVN@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function (DUF3494)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF3494
GNS2_k127_6105708_8	379066.GAU_3062	7.901e-33	132.0	COG1586@1|root,COG1586@2|Bacteria,1ZV1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GNS2_k127_6105708_2	1410661.JNKW01000004_gene1720	1.921e-103	347.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GNS2_k127_6105708_1	234267.Acid_1486	3.326e-127	421.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GNS2_k127_6105708_0	525904.Tter_0805	1.554e-171	548.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GNS2_k127_6105708_3	247490.KSU1_C0173	4.885e-81	286.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GNS2_k127_6105708_7	1331060.RLDS_10190	5.761e-43	162.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GNS2_k127_6105708_6	861299.J421_2451	4.207e-54	212.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GNS2_k127_6130492_2	382464.ABSI01000012_gene2201	2.424e-09	66.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
GNS2_k127_6130492_1	378806.STAUR_4666	7.073e-63	227.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
GNS2_k127_6130492_0	861299.J421_3595	2.251e-91	308.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GNS2_k127_6226990_2	485916.Dtox_4271	0.0007277	51.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GNS2_k127_6226990_0	886293.Sinac_2707	9.731e-50	198.0	COG1215@1|root,COG1215@2|Bacteria,2J0YZ@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_6226990_1	1198232.CYCME_1448	1.178e-38	156.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_6297333_1	234267.Acid_5890	2.83e-165	537.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
GNS2_k127_6297333_5	1121468.AUBR01000046_gene1904	1.238e-54	207.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,42GIT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GNS2_k127_6297333_9	1303518.CCALI_02307	5.289e-18	98.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,Thioredoxin_7
GNS2_k127_6297333_4	886293.Sinac_3852	1.997e-81	287.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GNS2_k127_6297333_3	886293.Sinac_3851	2.279e-84	285.0	COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes	203682|Planctomycetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
GNS2_k127_6297333_7	439235.Dalk_1593	7.067e-36	149.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria,2MPGU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GNS2_k127_6297333_8	404589.Anae109_2892	6.112e-31	143.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42URW@68525|delta/epsilon subdivisions,2WQAX@28221|Deltaproteobacteria,2Z1XF@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GNS2_k127_6297333_0	589924.Ferp_0317	0.0	1371.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GNS2_k127_6297333_2	338963.Pcar_1613	1.1e-137	447.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GNS2_k127_6297333_6	204669.Acid345_1679	1.052e-38	154.0	COG0531@1|root,COG0531@2|Bacteria,3Y6AZ@57723|Acidobacteria,2JME9@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GNS2_k127_6304997_1	765869.BDW_00250	3.987e-42	159.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2MTIQ@213481|Bdellovibrionales,2WJK4@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GNS2_k127_6304997_3	1267535.KB906767_gene2169	2.706e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,3Y7T2@57723|Acidobacteria,2JP3F@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
GNS2_k127_6304997_2	861299.J421_1517	9.587e-20	101.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6304997_0	1379698.RBG1_1C00001G0420	5.113e-75	263.0	COG0671@1|root,COG0671@2|Bacteria,2NQMG@2323|unclassified Bacteria	2|Bacteria	I	Phosphoesterase, PA-phosphatase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
GNS2_k127_6353748_2	1128421.JAGA01000003_gene2784	1.392e-44	175.0	COG0457@1|root,COG0457@2|Bacteria	1128421.JAGA01000003_gene2784|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6353748_0	357808.RoseRS_3336	4.556e-237	745.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
GNS2_k127_6353748_1	1122612.AUBA01000013_gene316	1.322e-73	267.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K0H7@204457|Sphingomonadales	204457|Sphingomonadales	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GNS2_k127_6353748_3	926550.CLDAP_10400	1.27e-38	155.0	COG1216@1|root,COG1216@2|Bacteria,2G7Y1@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6362256_1	1068980.ARVW01000001_gene7179	1.637e-16	82.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GNS2_k127_6362256_0	880073.Calab_1892	1.891e-59	230.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
GNS2_k127_6374653_1	290397.Adeh_1417	2.53e-245	772.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_6374653_5	340.xcc-b100_2147	6.35e-07	57.0	2EUIT@1|root,33N0U@2|Bacteria,1NMNE@1224|Proteobacteria,1SHKN@1236|Gammaproteobacteria,1X7S4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GNS2_k127_6374653_6	1379270.AUXF01000007_gene963	1.136e-06	55.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
GNS2_k127_6374653_3	1379698.RBG1_1C00001G1603	1.747e-62	217.0	COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria	2|Bacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GNS2_k127_6374653_2	904314.SEVCU012_2305	2.258e-65	228.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,4GXNQ@90964|Staphylococcaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
GNS2_k127_6374653_0	661367.LLO_0483	5.079e-278	871.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1JDM7@118969|Legionellales	118969|Legionellales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GNS2_k127_6374653_4	234267.Acid_5120	2.189e-12	80.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria	57723|Acidobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GNS2_k127_6374985_10	375286.mma_1622	1.134e-09	65.0	COG0702@1|root,COG0702@2|Bacteria,1QR3E@1224|Proteobacteria,2VPUM@28216|Betaproteobacteria,4743T@75682|Oxalobacteraceae	28216|Betaproteobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GNS2_k127_6374985_9	118166.JH976537_gene4796	1.648e-27	114.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
GNS2_k127_6374985_12	671143.DAMO_0014	2.731e-06	53.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GNS2_k127_6374985_6	1382359.JIAL01000001_gene2662	5.577e-52	197.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GNS2_k127_6374985_3	1267534.KB906755_gene3928	1.81e-72	253.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
GNS2_k127_6374985_2	861299.J421_3477	9.677e-80	274.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
GNS2_k127_6374985_5	1340493.JNIF01000003_gene3320	1.152e-55	198.0	COG3063@1|root,COG3063@2|Bacteria,3Y868@57723|Acidobacteria	57723|Acidobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GNS2_k127_6374985_8	330214.NIDE4039	1.648e-33	139.0	COG0247@1|root,COG0247@2|Bacteria,3J187@40117|Nitrospirae	40117|Nitrospirae	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
GNS2_k127_6374985_1	330214.NIDE4040	8.859e-111	379.0	COG0247@1|root,COG1146@1|root,COG0247@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3,1.2.7.3	ko:K00113,ko:K00176,ko:K05524,ko:K13795,ko:K13796	ko00020,ko00564,ko00720,ko01100,ko01110,ko01120,ko01200,map00020,map00564,map00720,map01100,map01110,map01120,map01200	M00009,M00011,M00173,M00620	R00848,R01197	RC00004,RC00029,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,DUF3470,DUF3501,Fer4,Fer4_8
GNS2_k127_6374985_4	330214.NIDE4041	2.515e-71	250.0	COG1592@1|root,COG1592@2|Bacteria,3J0RY@40117|Nitrospirae	40117|Nitrospirae	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GNS2_k127_6374985_7	1121403.AUCV01000001_gene907	9.908e-34	141.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,2MKMK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GNS2_k127_6374985_11	316274.Haur_3093	3.198e-07	59.0	COG0745@1|root,COG0745@2|Bacteria	316274.Haur_3093|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6374985_0	1173020.Cha6605_3117	9.092e-206	664.0	COG1626@1|root,COG1626@2|Bacteria,1G2E6@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
GNS2_k127_638180_3	266117.Rxyl_3124	2.377e-07	54.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CQEJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_638180_1	292459.STH2398	7.761e-48	194.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
GNS2_k127_638180_2	1116232.AHBF01000125_gene9473	2.356e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_638180_0	378806.STAUR_1666	4.812e-142	456.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
GNS2_k127_6390739_0	1348657.M622_18790	8.177e-13	78.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6390739_1	1394178.AWOO02000046_gene6479	1.454e-12	78.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4EIUK@85012|Streptosporangiales	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
GNS2_k127_6390739_2	330779.Saci_2026	3.355e-05	52.0	COG0457@1|root,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GNS2_k127_6393654_3	1121422.AUMW01000011_gene150	2.04e-45	179.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,261HE@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_6393654_4	404589.Anae109_0126	7.332e-27	113.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
GNS2_k127_6393654_0	330214.NIDE0781	1.462e-121	404.0	COG0462@1|root,COG0462@2|Bacteria,3J0D0@40117|Nitrospirae	40117|Nitrospirae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GNS2_k127_6393654_1	1382359.JIAL01000001_gene1377	5.491e-52	192.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GNS2_k127_6393654_2	546271.Selsp_1215	1.396e-48	186.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes	909932|Negativicutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GNS2_k127_6393654_5	1340493.JNIF01000004_gene998	6.715e-26	111.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GNS2_k127_640426_0	1192034.CAP_8276	1.864e-110	379.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GNS2_k127_640426_2	314285.KT71_16656	2.147e-53	207.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,1J9BV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GNS2_k127_640426_3	234267.Acid_4496	2.173e-35	141.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GNS2_k127_640426_7	472759.Nhal_3484	8.904e-13	72.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GNS2_k127_640426_6	204669.Acid345_2636	1.195e-17	88.0	COG3744@1|root,COG3744@2|Bacteria,3Y8F1@57723|Acidobacteria,2JNDR@204432|Acidobacteriia	204432|Acidobacteriia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GNS2_k127_640426_5	1385517.N800_08385	7.286e-29	130.0	2EJ52@1|root,33CW9@2|Bacteria,1PD05@1224|Proteobacteria,1SY6A@1236|Gammaproteobacteria,1X79D@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_640426_1	1133849.O3I_023520	2.241e-63	235.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4FW6C@85025|Nocardiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GNS2_k127_640426_4	1173024.KI912148_gene4502	1.446e-30	122.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
GNS2_k127_6427055_1	903818.KI912268_gene2412	1.656e-185	585.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GNS2_k127_6427055_0	234267.Acid_5457	0.0	1135.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
GNS2_k127_6453859_0	1382359.JIAL01000001_gene86	7.218e-112	372.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_6453859_1	518766.Rmar_0669	9.556e-71	256.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
GNS2_k127_6474209_4	335543.Sfum_2671	1.13e-07	63.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MR9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	transporter, DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
GNS2_k127_6474209_2	335543.Sfum_2672	2.963e-102	359.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
GNS2_k127_6474209_1	335543.Sfum_2673	1.672e-115	379.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
GNS2_k127_6474209_0	404589.Anae109_1720	3.125e-136	448.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
GNS2_k127_6474209_3	641491.DND132_0207	6.019e-37	157.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GNS2_k127_6504312_6	1519464.HY22_08585	1.239e-103	351.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GNS2_k127_6504312_7	1538644.KO02_23380	1.906e-36	147.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
GNS2_k127_6504312_3	640081.Dsui_3023	1.314e-123	415.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,2KVRY@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
GNS2_k127_6504312_10	204669.Acid345_1569	2.748e-11	72.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
GNS2_k127_6504312_2	234267.Acid_7272	9.545e-167	539.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
GNS2_k127_6504312_0	1384054.N790_13005	1.826e-203	648.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GNS2_k127_6504312_9	1173028.ANKO01000215_gene6262	1.862e-18	90.0	COG1547@1|root,COG1547@2|Bacteria,1G7QG@1117|Cyanobacteria,1HBGH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
GNS2_k127_6504312_4	234267.Acid_7187	7.171e-112	389.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
GNS2_k127_6504312_1	649747.HMPREF0083_00362	3.787e-195	631.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,26SKK@186822|Paenibacillaceae	91061|Bacilli	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GNS2_k127_6504312_5	744872.Spica_2588	5.58e-110	375.0	COG0248@1|root,COG0248@2|Bacteria,2J5XU@203691|Spirochaetes	203691|Spirochaetes	FP	Ppx GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GNS2_k127_6517479_1	671143.DAMO_2824	5.025e-64	224.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
GNS2_k127_6517479_0	1242864.D187_009241	1.156e-166	564.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions,2WVIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_6580555_3	96561.Dole_1244	9.573e-71	251.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
GNS2_k127_6580555_2	469383.Cwoe_4532	5.373e-80	273.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria	201174|Actinobacteria	J	Flavin-nucleotide-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Acetyltransf_3,Pyridox_ox_2
GNS2_k127_6580555_1	1385519.N801_05830	3.433e-89	315.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
GNS2_k127_6580555_4	1408813.AYMG01000013_gene1359	4.623e-41	175.0	COG5478@1|root,COG5478@2|Bacteria,4NPSX@976|Bacteroidetes,1IT1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
GNS2_k127_6580555_5	118163.Ple7327_2143	7.137e-05	51.0	2E789@1|root,33088@2|Bacteria,1G951@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6580555_0	335543.Sfum_3677	7.909e-156	508.0	COG1414@1|root,COG2374@1|root,COG1414@2|Bacteria,COG2374@2|Bacteria,1Q48S@1224|Proteobacteria,42YKZ@68525|delta/epsilon subdivisions,2WUID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
GNS2_k127_6583406_1	1283299.AUKG01000002_gene4691	1.743e-19	103.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_6583406_0	1121448.DGI_2478	3.708e-20	100.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_6621785_0	1128421.JAGA01000002_gene389	4.188e-46	184.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_6621785_2	710686.Mycsm_05272	9.234e-14	84.0	COG3011@1|root,COG3011@2|Bacteria,2GN4W@201174|Actinobacteria,23614@1762|Mycobacteriaceae	201174|Actinobacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
GNS2_k127_6621785_1	713587.THITH_13720	8.388e-23	105.0	COG0223@1|root,COG0223@2|Bacteria	2|Bacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	2.1.2.2,2.1.2.9	ko:K00604,ko:K11175	ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,map00230,map00670,map00970,map01100,map01110,map01130	M00048	R03940,R04325,R04326	RC00026,RC00165,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GNS2_k127_6623013_0	357808.RoseRS_3414	1.575e-86	299.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3762T@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GNS2_k127_6628396_0	101510.RHA1_ro05584	1.437e-24	111.0	2DM5T@1|root,31U0Y@2|Bacteria,2HHDM@201174|Actinobacteria,4FXV2@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GNS2_k127_6641656_2	640081.Dsui_3157	6.654e-11	66.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,2VMEK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Pfam Fatty acid	cti	-	-	-	-	-	-	-	-	-	-	-	CTI
GNS2_k127_6641656_1	1348663.KCH_08390	2.168e-16	81.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria,2M3ED@2063|Kitasatospora	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GNS2_k127_6641656_3	290397.Adeh_2144	1.149e-08	67.0	COG5662@1|root,COG5662@2|Bacteria,1R8JM@1224|Proteobacteria,434SA@68525|delta/epsilon subdivisions,2WZ3C@28221|Deltaproteobacteria,2Z18J@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GNS2_k127_6641656_0	1123258.AQXZ01000019_gene3262	2.844e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4FVNC@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_671949_2	1385517.N800_10145	2.507e-63	231.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1X4Y2@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
GNS2_k127_671949_0	313596.RB2501_02395	2.162e-131	433.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GNS2_k127_671949_3	1192034.CAP_6616	2.799e-27	119.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2Z1VX@29|Myxococcales	28221|Deltaproteobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GNS2_k127_671949_4	215803.DB30_4371	2.208e-10	75.0	COG3204@1|root,COG3204@2|Bacteria,1P76C@1224|Proteobacteria	1224|Proteobacteria	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
GNS2_k127_671949_1	684949.ATTJ01000003_gene3328	5.05e-112	375.0	COG0535@1|root,COG0535@2|Bacteria,1WICG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GNS2_k127_671949_5	215803.DB30_7218	0.0001291	46.0	COG0412@1|root,COG0412@2|Bacteria,1QRBY@1224|Proteobacteria,43E13@68525|delta/epsilon subdivisions,2WZE4@28221|Deltaproteobacteria,2Z1XS@29|Myxococcales	28221|Deltaproteobacteria	Q	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6720619_3	1121127.JAFA01000035_gene3516	2.76e-22	106.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1K363@119060|Burkholderiaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_6720619_2	1232410.KI421416_gene2621	1.77e-38	154.0	2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6720619_1	330214.NIDE0698	3.195e-54	202.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycA	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	Cytochrom_C,Cytochrome_CBB3
GNS2_k127_6720619_0	378806.STAUR_7018	1.36e-107	354.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GNS2_k127_6725083_2	1121930.AQXG01000032_gene949	2.765e-42	165.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IPFI@117747|Sphingobacteriia	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
GNS2_k127_6725083_0	404589.Anae109_4262	8.305e-73	263.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WNCM@28221|Deltaproteobacteria,2Z20A@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GNS2_k127_6725083_1	1382356.JQMP01000003_gene1584	3.267e-70	249.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
GNS2_k127_6758410_5	485913.Krac_7501	2.542e-32	130.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GNS2_k127_6758410_3	330214.NIDE3560	1.137e-65	240.0	COG1894@1|root,COG1894@2|Bacteria,3J0WA@40117|Nitrospirae	40117|Nitrospirae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GNS2_k127_6758410_10	886293.Sinac_2991	2.129e-08	66.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6758410_8	1123242.JH636435_gene2841	2.103e-09	70.0	2EC0X@1|root,33605@2|Bacteria,2J0WR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6758410_0	1232410.KI421414_gene2832	8.779e-200	637.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,43SYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GNS2_k127_6758410_7	1519464.HY22_06680	2.815e-16	89.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GNS2_k127_6758410_2	448385.sce7131	1.927e-70	247.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GNS2_k127_6758410_6	744985.HIMB59_00008530	7.456e-21	93.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,4BQNB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GNS2_k127_6758410_4	366602.Caul_2159	1.187e-41	166.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PDZ DHR GLGF domain protein	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GNS2_k127_6758410_9	1499967.BAYZ01000184_gene4554	5.542e-09	65.0	COG4995@1|root,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
GNS2_k127_6899619_7	99598.Cal7507_2240	9.043e-38	162.0	COG0784@1|root,COG2199@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG5002@2|Bacteria,1GHDT@1117|Cyanobacteria,1HJI5@1161|Nostocales	1117|Cyanobacteria	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
GNS2_k127_6899619_4	768671.ThimaDRAFT_1668	8.359e-55	196.0	COG0758@1|root,COG0758@2|Bacteria,1MZGB@1224|Proteobacteria,1S95S@1236|Gammaproteobacteria,1WYBS@135613|Chromatiales	135613|Chromatiales	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
GNS2_k127_6899619_5	688245.CtCNB1_1740	8.659e-44	168.0	COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
GNS2_k127_6899619_11	1550073.JROH01000009_gene1300	4.035e-06	51.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GNS2_k127_6899619_6	1163407.UU7_04927	1.397e-39	162.0	COG2885@1|root,COG2885@2|Bacteria,1RB3C@1224|Proteobacteria,1S36Z@1236|Gammaproteobacteria,1X77V@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_6899619_8	448385.sce6271	1.874e-33	136.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,42PDG@68525|delta/epsilon subdivisions,2WKNJ@28221|Deltaproteobacteria,2Z1YT@29|Myxococcales	28221|Deltaproteobacteria	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GNS2_k127_6899619_9	1415778.JQMM01000001_gene967	2.835e-22	100.0	COG4974@1|root,COG4974@2|Bacteria,1P8X9@1224|Proteobacteria,1SK66@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GNS2_k127_6899619_10	411684.HPDFL43_17496	2.005e-20	96.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,43M00@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
GNS2_k127_6899619_1	234267.Acid_1869	3.346e-126	433.0	COG0031@1|root,COG0031@2|Bacteria,3Y71B@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_6899619_0	485915.Dret_1750	5.661e-273	861.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
GNS2_k127_6899619_3	215803.DB30_0760	2.451e-87	295.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2Z1ED@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GNS2_k127_6899619_2	243231.GSU0094	1.364e-118	402.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GNS2_k127_6930331_1	543632.JOJL01000126_gene9549	2.074e-05	47.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DGWQ@85008|Micromonosporales	201174|Actinobacteria	L	COG5659 FOG Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GNS2_k127_6930331_0	378806.STAUR_0336	2.048e-123	414.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2Z18Z@29|Myxococcales	28221|Deltaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
GNS2_k127_6944901_7	861299.J421_4438	4.041e-38	148.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
GNS2_k127_6944901_3	861299.J421_3658	8.635e-97	344.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_3658|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
GNS2_k127_6944901_9	1123503.KB908058_gene1062	1.856e-05	57.0	2FGHI@1|root,348DF@2|Bacteria,1P1IU@1224|Proteobacteria,2UU45@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6944901_10	1131269.AQVV01000035_gene875	0.000533	53.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000035_gene875|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6944901_1	392499.Swit_3144	5.876e-216	707.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2JZUI@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
GNS2_k127_6944901_5	1121937.AUHJ01000010_gene1633	2.701e-56	211.0	COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Transglut_core
GNS2_k127_6944901_2	234267.Acid_3938	4.409e-117	409.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
GNS2_k127_6944901_0	671143.DAMO_2938	8.384e-274	852.0	COG1274@1|root,COG1274@2|Bacteria,2NQRD@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	pckG	-	4.1.1.32,4.1.1.49	ko:K01596,ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003,M00170	R00341,R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP,PEPCK_C,PEPCK_N
GNS2_k127_6944901_4	1384054.N790_03430	3.56e-95	328.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1X3WV@135614|Xanthomonadales	135614|Xanthomonadales	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GNS2_k127_6944901_8	402626.Rpic_0116	1.024e-17	93.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,1K2QQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	carboxylase	accA1	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GNS2_k127_6944901_6	485913.Krac_6823	6.954e-48	177.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GNS2_k127_694868_0	1382356.JQMP01000004_gene486	0.0	1054.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GNS2_k127_694868_2	861299.J421_3791	1.705e-87	325.0	2DB86@1|root,2Z7QD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
GNS2_k127_694868_1	1173027.Mic7113_2540	1.008e-97	327.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
GNS2_k127_694868_3	1500893.JQNB01000001_gene1494	0.0002695	49.0	2ADS7@1|root,313HQ@2|Bacteria,1QD8F@1224|Proteobacteria,1T95P@1236|Gammaproteobacteria,1XBQB@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_6952464_0	635013.TherJR_0047	3.342e-161	524.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,260WN@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM acetaldehyde dehydrogenase (acetylating)	-	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
GNS2_k127_6952464_1	204669.Acid345_0549	1.981e-96	336.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GNS2_k127_6952464_2	1303518.CCALI_01457	4.447e-44	170.0	COG0606@1|root,COG0606@2|Bacteria	2|Bacteria	O	chelatase, subunit chli	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GNS2_k127_6990635_1	1123242.JH636435_gene2917	4.187e-79	287.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GNS2_k127_6990635_0	869210.Marky_0500	1.549e-112	396.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GNS2_k127_6990635_2	1123377.AUIV01000025_gene381	3.201e-35	144.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GNS2_k127_7006576_0	289376.THEYE_A2065	1.474e-59	212.0	COG2201@1|root,COG2201@2|Bacteria,3J0X3@40117|Nitrospirae	40117|Nitrospirae	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
GNS2_k127_7006576_1	1232410.KI421413_gene817	5.647e-17	93.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
GNS2_k127_7025734_3	671143.DAMO_0297	6.528e-55	207.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_7025734_2	292459.STH1622	4.452e-72	260.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes	1239|Firmicutes	L	Exonuclease	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GNS2_k127_7025734_1	313596.RB2501_06945	2.804e-75	287.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrroloquinoline quinone biosynthesis protein PqqB	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
GNS2_k127_7025734_0	1047013.AQSP01000135_gene1619	8.589e-292	916.0	COG1205@1|root,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
GNS2_k127_7025734_4	401053.AciPR4_2703	4.512e-08	65.0	2DVRE@1|root,33WVZ@2|Bacteria,3Y60B@57723|Acidobacteria,2JMWX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7036453_1	1162668.LFE_2059	3.042e-133	436.0	COG0104@1|root,COG0104@2|Bacteria,3J0FV@40117|Nitrospirae	40117|Nitrospirae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GNS2_k127_7036453_0	867903.ThesuDRAFT_00368	1.567e-158	514.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,3WCEP@538999|Clostridiales incertae sedis	186801|Clostridia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GNS2_k127_7040807_0	1128421.JAGA01000003_gene2905	1.857e-124	411.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
GNS2_k127_7042282_1	1121396.KB892900_gene2073	1.235e-26	119.0	COG2885@1|root,COG2885@2|Bacteria,1R6QU@1224|Proteobacteria,42V4P@68525|delta/epsilon subdivisions,2WRRK@28221|Deltaproteobacteria,2MM6J@213118|Desulfobacterales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_7042282_2	118166.JH976538_gene5205	0.0006847	51.0	COG0457@1|root,COG0457@2|Bacteria,1G5S0@1117|Cyanobacteria,1HC37@1150|Oscillatoriales	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7042282_0	211165.AJLN01000145_gene1259	5.007e-93	320.0	COG0823@1|root,COG0823@2|Bacteria,1G28F@1117|Cyanobacteria,1JKQG@1189|Stigonemataceae	1117|Cyanobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7053217_3	1173264.KI913949_gene3544	1.756e-25	110.0	COG4319@1|root,COG4319@2|Bacteria,1G6QY@1117|Cyanobacteria,1HBIC@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GNS2_k127_7053217_0	83406.HDN1F_19090	7.064e-102	359.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J88C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
GNS2_k127_7053217_2	1198114.AciX9_1240	4.455e-62	225.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria,2JI6C@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GNS2_k127_7053217_1	1340493.JNIF01000003_gene3269	1.027e-72	252.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria	57723|Acidobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_7054102_2	1121106.JQKB01000049_gene3064	2.712e-85	293.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,2JVSA@204441|Rhodospirillales	204441|Rhodospirillales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GNS2_k127_7054102_5	1267534.KB906760_gene1554	5.205e-28	117.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7054102_1	1267535.KB906767_gene2749	1.107e-116	384.0	COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GNS2_k127_7054102_6	861299.J421_2146	2.485e-12	68.0	COG4941@1|root,COG4941@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_7054102_4	399739.Pmen_1484	9.257e-29	120.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,1YE2C@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,TPR_2
GNS2_k127_7054102_7	404589.Anae109_1986	6.682e-11	75.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,42VG3@68525|delta/epsilon subdivisions,2WRB7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7054102_0	234267.Acid_5939	1.929e-139	459.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_7054102_8	397278.JOJN01000001_gene3071	3.721e-09	57.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4DUCQ@85009|Propionibacteriales	201174|Actinobacteria	H	SNO glutamine amidotransferase family	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
GNS2_k127_707098_1	1121451.DESAM_20915	3.08e-17	84.0	COG1028@1|root,COG2030@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,1Q55V@1224|Proteobacteria,430M5@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GNS2_k127_707098_0	28444.JODQ01000014_gene6962	9.545e-80	282.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria,4EM8A@85012|Streptosporangiales	201174|Actinobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
GNS2_k127_724451_4	497964.CfE428DRAFT_4359	3.162e-17	86.0	COG3000@1|root,COG3000@2|Bacteria,46W5T@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_724451_0	1121904.ARBP01000007_gene2888	3.198e-220	715.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GNS2_k127_724451_1	479434.Sthe_2327	1.379e-117	394.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GNS2_k127_724451_2	479434.Sthe_2326	5.475e-75	266.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
GNS2_k127_724451_3	886293.Sinac_1892	1.123e-34	134.0	COG0407@1|root,COG0407@2|Bacteria,2IXZG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,URO-D
GNS2_k127_725246_6	398767.Glov_2056	2.585e-27	114.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hyaS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3332	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
GNS2_k127_725246_8	1094715.CM001373_gene1338	1.483e-12	71.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_725246_9	1458275.AZ34_10270	1.491e-12	78.0	COG3000@1|root,COG3000@2|Bacteria,1N39U@1224|Proteobacteria,2VWC0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_725246_4	483219.LILAB_16725	1.603e-38	162.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,43BK7@68525|delta/epsilon subdivisions,2X5W4@28221|Deltaproteobacteria,2Z37Z@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GNS2_k127_725246_1	1125863.JAFN01000001_gene322	3.006e-96	323.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GNS2_k127_725246_5	204669.Acid345_4277	3.241e-34	153.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_4277|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_725246_11	404589.Anae109_0479	8.796e-11	76.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
GNS2_k127_725246_10	391625.PPSIR1_16480	4.804e-11	68.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
GNS2_k127_725246_12	316274.Haur_4686	2.87e-10	67.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
GNS2_k127_725246_7	1121920.AUAU01000011_gene151	4.136e-15	79.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
GNS2_k127_725246_3	1232410.KI421412_gene412	4.504e-46	179.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
GNS2_k127_725246_0	644966.Tmar_1263	2.833e-105	355.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
GNS2_k127_725246_2	1128421.JAGA01000001_gene2429	2.676e-75	286.0	COG0181@1|root,COG0181@2|Bacteria,2NP8M@2323|unclassified Bacteria	2|Bacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01749,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
GNS2_k127_7256859_29	469383.Cwoe_4173	1.291e-39	160.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
GNS2_k127_7256859_25	671143.DAMO_2863	2.789e-50	193.0	COG2096@1|root,COG2096@2|Bacteria,2NPP8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pduO	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
GNS2_k127_7256859_5	869210.Marky_1642	3.01e-160	516.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GNS2_k127_7256859_34	290397.Adeh_3512	9.114e-24	113.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,1PSZK@1224|Proteobacteria,43A90@68525|delta/epsilon subdivisions,2WXQZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
GNS2_k127_7256859_23	886293.Sinac_2319	4.888e-64	237.0	COG0432@1|root,COG0432@2|Bacteria,2IZ7Q@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GNS2_k127_7256859_28	316067.Geob_2998	1.809e-45	173.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42W4B@68525|delta/epsilon subdivisions,2WP0P@28221|Deltaproteobacteria,43UMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GNS2_k127_7256859_32	365528.KB891104_gene3708	2.964e-27	127.0	COG1028@1|root,COG1028@2|Bacteria,2HAYI@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GNS2_k127_7256859_38	267608.RSc3099	2.416e-09	65.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2VSHI@28216|Betaproteobacteria,1K79N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,DUF4437
GNS2_k127_7256859_2	198467.NP92_11710	2.76e-195	628.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,21WRR@150247|Anoxybacillus	91061|Bacilli	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GNS2_k127_7256859_10	234267.Acid_1537	3.292e-129	428.0	COG0124@1|root,COG0124@2|Bacteria,3Y3IY@57723|Acidobacteria	57723|Acidobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GNS2_k127_7256859_22	204669.Acid345_1206	4.228e-64	224.0	COG0663@1|root,COG0663@2|Bacteria,3Y4A5@57723|Acidobacteria,2JJ1R@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GNS2_k127_7256859_18	1169152.AXVD01000015_gene1088	5.687e-77	276.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4FWIG@85025|Nocardiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GNS2_k127_7256859_30	1322246.BN4_12364	1.111e-38	160.0	COG0412@1|root,COG0412@2|Bacteria,1QE6Y@1224|Proteobacteria,431G4@68525|delta/epsilon subdivisions,2WWQW@28221|Deltaproteobacteria,2MEUZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7256859_31	35754.JNYJ01000045_gene4033	5.634e-34	147.0	COG1874@1|root,COG3828@1|root,COG1874@2|Bacteria,COG3828@2|Bacteria,2I3AJ@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Ricin_B_lectin,ThuA
GNS2_k127_7256859_0	379066.GAU_3073	2.317e-234	734.0	COG1012@1|root,COG1012@2|Bacteria,1ZSRK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GNS2_k127_7256859_40	269799.Gmet_3122	7.18e-05	50.0	COG0607@1|root,COG0607@2|Bacteria,1PE42@1224|Proteobacteria,42V5T@68525|delta/epsilon subdivisions,2WSHC@28221|Deltaproteobacteria,43VCQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GNS2_k127_7256859_27	1340493.JNIF01000003_gene2146	1.679e-47	181.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
GNS2_k127_7256859_3	1089550.ATTH01000001_gene1831	3.48e-194	639.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
GNS2_k127_7256859_24	700598.Niako_5053	6.887e-63	240.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
GNS2_k127_7256859_21	251221.35211558	7.593e-69	263.0	COG1404@1|root,COG2706@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_S8,TIG,VCBS
GNS2_k127_7256859_6	247490.KSU1_C0714	1.312e-153	520.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
GNS2_k127_7256859_17	99598.Cal7507_6086	5.78e-82	287.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GNS2_k127_7256859_14	215803.DB30_1540	3.819e-104	354.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,42N55@68525|delta/epsilon subdivisions,2WVAY@28221|Deltaproteobacteria,2YWI6@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GNS2_k127_7256859_8	1192034.CAP_1066	1.133e-130	437.0	COG3975@1|root,COG3975@2|Bacteria,1MYAB@1224|Proteobacteria,439JT@68525|delta/epsilon subdivisions,2X4WE@28221|Deltaproteobacteria,2YZR0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7256859_1	1123073.KB899241_gene3395	2.165e-198	658.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_7256859_11	251221.35211122	6.168e-115	413.0	COG3211@1|root,COG3211@2|Bacteria,1G1TG@1117|Cyanobacteria	2|Bacteria	S	PFAM Bacterial protein of	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
GNS2_k127_7256859_12	1041930.Mtc_2380	1.701e-114	381.0	COG1915@1|root,arCOG04422@2157|Archaea,2XTUK@28890|Euryarchaeota,2NAC6@224756|Methanomicrobia	224756|Methanomicrobia	S	LOR SDH bifunctional enzyme conserved	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
GNS2_k127_7256859_15	926569.ANT_11190	2.568e-99	332.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GNS2_k127_7256859_19	483219.LILAB_10840	3.298e-72	253.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
GNS2_k127_7256859_36	1089553.Tph_c12330	9.893e-16	78.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,24SFG@186801|Clostridia,42HA6@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
GNS2_k127_7256859_13	215803.DB30_1202	2.458e-114	374.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GNS2_k127_7256859_4	204669.Acid345_2609	9.854e-168	543.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
GNS2_k127_7256859_33	945713.IALB_0843	6.347e-27	129.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
GNS2_k127_7256859_35	1469557.JSWF01000014_gene2664	2.864e-21	110.0	COG3291@1|root,COG3391@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
GNS2_k127_7256859_26	1095769.CAHF01000011_gene2402	5.15e-50	183.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4741A@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GNS2_k127_7256859_9	1121920.AUAU01000002_gene2162	3.135e-129	419.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria	57723|Acidobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GNS2_k127_7256859_7	204669.Acid345_3875	6.791e-148	478.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GNS2_k127_7256859_16	1121033.AUCF01000006_gene4251	5.938e-84	301.0	COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,2TSJ4@28211|Alphaproteobacteria,2JS9B@204441|Rhodospirillales	204441|Rhodospirillales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GNS2_k127_7256859_20	1349767.GJA_3764	1.128e-70	251.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GNS2_k127_7256859_37	96561.Dole_2317	3.36e-15	77.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7256859_39	1089550.ATTH01000001_gene2408	2.478e-09	65.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	2.3.1.43	ko:K00650	ko00564,ko04979,map00564,map04979	-	R02114	RC00037,RC00055	ko00000,ko00001,ko01000	-	-	-	DUF900,LCAT,Peptidase_C14
GNS2_k127_7270409_1	338963.Pcar_1002	4.406e-87	294.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,43UAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
GNS2_k127_7270409_4	1278073.MYSTI_02341	8.314e-64	229.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
GNS2_k127_7270409_3	580332.Slit_1271	3.525e-65	238.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GNS2_k127_7270409_5	1379698.RBG1_1C00001G1213	0.0006407	49.0	COG1956@1|root,COG1956@2|Bacteria,2NPKF@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
GNS2_k127_7270409_2	1125863.JAFN01000001_gene1971	3.814e-74	263.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria	1224|Proteobacteria	EM	Belongs to the DapA family	yagE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GNS2_k127_7270409_0	1121920.AUAU01000002_gene2003	1.243e-89	306.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
GNS2_k127_7276519_8	1121938.AUDY01000008_gene920	9.902e-13	70.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli	91061|Bacilli	O	redox protein regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GNS2_k127_7276519_4	324602.Caur_3425	5.736e-63	246.0	COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi,375D9@32061|Chloroflexia	32061|Chloroflexia	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
GNS2_k127_7276519_2	448385.sce6263	2.85e-99	346.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
GNS2_k127_7276519_1	404589.Anae109_3731	3.17e-244	787.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
GNS2_k127_7276519_6	404589.Anae109_4368	1.38e-26	122.0	COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,42X79@68525|delta/epsilon subdivisions,2WXA0@28221|Deltaproteobacteria,2YVD9@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GNS2_k127_7276519_5	1379698.RBG1_1C00001G0810	2.772e-48	185.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
GNS2_k127_7276519_7	1128421.JAGA01000003_gene2880	5.885e-17	92.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GNS2_k127_7276519_3	1128421.JAGA01000003_gene2879	6.903e-71	246.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GNS2_k127_7276519_0	234267.Acid_0498	6.894e-275	852.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GNS2_k127_7312436_8	1210884.HG799462_gene8049	8.544e-05	47.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_7312436_5	575540.Isop_2112	4.934e-15	85.0	COG1277@1|root,COG1277@2|Bacteria,2J0ZV@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GNS2_k127_7312436_1	575540.Isop_2113	2.148e-88	315.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_7312436_3	1047013.AQSP01000128_gene413	2.822e-25	117.0	2DU2Y@1|root,33NQT@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
GNS2_k127_7312436_4	1121013.P873_05235	2.536e-15	87.0	COG3672@1|root,COG3672@2|Bacteria,1RKG9@1224|Proteobacteria,1S8MS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GNS2_k127_7312436_6	392500.Swoo_4626	1.462e-09	64.0	2EBER@1|root,31PRF@2|Bacteria,1QMEM@1224|Proteobacteria,1TJPK@1236|Gammaproteobacteria,2QE58@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
GNS2_k127_7312436_9	666681.M301_0745	0.0006036	52.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,2VNJT@28216|Betaproteobacteria,2KMD5@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
GNS2_k127_7312436_2	56110.Oscil6304_4756	2.916e-37	150.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1GDJY@1117|Cyanobacteria,1H8JX@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GNS2_k127_7312436_0	111781.Lepto7376_2343	7.873e-143	462.0	COG0457@1|root,COG0457@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Methyltransf_21,TPR_1,TPR_11,TPR_14,TPR_16,TPR_17,TPR_2,TPR_8
GNS2_k127_7326446_3	1121920.AUAU01000002_gene2081	1.445e-69	254.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria	57723|Acidobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
GNS2_k127_7326446_1	330214.NIDE3580	1.951e-80	283.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE3580|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
GNS2_k127_7326446_2	1278073.MYSTI_02336	4.04e-71	247.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GNS2_k127_7326446_4	521674.Plim_3505	5.683e-23	115.0	2DX1R@1|root,34301@2|Bacteria,2J54M@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
GNS2_k127_7326446_0	479434.Sthe_2480	9.155e-98	333.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
GNS2_k127_7342915_0	1382359.JIAL01000001_gene1316	1.222e-150	513.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria,2JKNM@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,UnbV_ASPIC,VCBS
GNS2_k127_7342915_1	452637.Oter_2944	1.482e-147	478.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GNS2_k127_7342915_6	1356852.N008_14530	1.541e-37	148.0	2DNUQ@1|root,32Z94@2|Bacteria,4NVH0@976|Bacteroidetes,47QAG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
GNS2_k127_7342915_4	443144.GM21_3434	7.783e-81	278.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,42NDF@68525|delta/epsilon subdivisions,2WJPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
GNS2_k127_7342915_2	215803.DB30_1749	1.324e-113	383.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GNS2_k127_7342915_8	760192.Halhy_4503	1.4e-23	113.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
GNS2_k127_7342915_3	479431.Namu_4403	2.28e-81	277.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GNS2_k127_7342915_5	215803.DB30_4350	1.15e-42	173.0	COG2227@1|root,COG2227@2|Bacteria,1QX75@1224|Proteobacteria,43E3D@68525|delta/epsilon subdivisions,2X7AR@28221|Deltaproteobacteria,2Z3ER@29|Myxococcales	28221|Deltaproteobacteria	H	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GNS2_k127_7342915_7	1262914.BN533_01455	2.241e-31	137.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4H1VQ@909932|Negativicutes	909932|Negativicutes	G	hopanoid biosynthesis associated protein HpnK	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
GNS2_k127_7346264_3	204669.Acid345_1618	3.722e-52	205.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_7346264_0	204669.Acid345_1619	1.269e-109	372.0	COG0577@1|root,COG0577@2|Bacteria,3Y4MY@57723|Acidobacteria,2JMXU@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_7346264_1	204669.Acid345_1620	1.36e-104	353.0	COG1136@1|root,COG1136@2|Bacteria,3Y4A6@57723|Acidobacteria,2JMVQ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_7346264_2	671143.DAMO_0267	1.527e-87	312.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
GNS2_k127_7346264_4	429009.Adeg_1268	1.666e-05	58.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia,42GGS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GNS2_k127_7391558_4	1047013.AQSP01000139_gene2367	1.754e-28	120.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	cymR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
GNS2_k127_7391558_3	1121013.P873_04650	8.268e-98	332.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
GNS2_k127_7391558_0	522306.CAP2UW1_0220	9.506e-145	485.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
GNS2_k127_7391558_1	62928.azo1335	2.358e-113	386.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
GNS2_k127_7391558_2	1118054.CAGW01000081_gene2700	2.718e-112	370.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,4H9XE@91061|Bacilli,26U4E@186822|Paenibacillaceae	91061|Bacilli	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
GNS2_k127_7391558_5	582899.Hden_2673	1.985e-25	110.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2TVZ3@28211|Alphaproteobacteria,3N6CU@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
GNS2_k127_7398411_0	1169152.AXVD01000002_gene3737	1.457e-118	402.0	COG3882@1|root,COG3882@2|Bacteria,2GNIM@201174|Actinobacteria,4G1UI@85025|Nocardiaceae	201174|Actinobacteria	Q	HAD-superfamily phosphatase, subfamily IIIC	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GNS2_k127_7398411_1	234267.Acid_4810	1.24e-45	180.0	COG1028@1|root,COG2030@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,3Y87D@57723|Acidobacteria	57723|Acidobacteria	IQ	MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GNS2_k127_7399218_0	1047013.AQSP01000109_gene2431	3.731e-52	203.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7399218_2	215803.DB30_0472	2.08e-28	123.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2Z083@29|Myxococcales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
GNS2_k127_7399218_1	1120972.AUMH01000005_gene911	1.221e-45	176.0	COG0129@1|root,COG0129@2|Bacteria,1UYPZ@1239|Firmicutes,4HCGG@91061|Bacilli	91061|Bacilli	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
GNS2_k127_7408227_1	103690.17130889	1.251e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,1GHDC@1117|Cyanobacteria,1HRAS@1161|Nostocales	1117|Cyanobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
GNS2_k127_7408227_0	1121396.KB892900_gene2074	8.675e-78	284.0	COG4249@1|root,COG4249@2|Bacteria,1MXS7@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
GNS2_k127_7474111_2	1192034.CAP_8276	5.707e-114	395.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GNS2_k127_7474111_6	670487.Ocepr_1114	1.547e-25	123.0	COG0797@1|root,COG1388@1|root,COG0797@2|Bacteria,COG1388@2|Bacteria,1WJRE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,LysM
GNS2_k127_7474111_1	357808.RoseRS_1428	8.657e-141	466.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi,375C1@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GNS2_k127_7474111_9	1121396.KB893094_gene4464	2.351e-11	78.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42PQN@68525|delta/epsilon subdivisions,2WMA2@28221|Deltaproteobacteria,2MJZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GNS2_k127_7474111_0	1448389.BAVQ01000007_gene4215	4.735e-168	553.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GNS2_k127_7474111_5	671143.DAMO_0171	5.527e-36	158.0	2C82G@1|root,32RK9@2|Bacteria,2NRTP@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GNS2_k127_7474111_3	525904.Tter_1537	1.763e-110	369.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
GNS2_k127_7474111_8	204669.Acid345_1307	9.722e-17	94.0	COG0839@1|root,COG0839@2|Bacteria,3Y4I4@57723|Acidobacteria,2JJ8B@204432|Acidobacteriia	204432|Acidobacteriia	C	plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GNS2_k127_7474111_7	1232410.KI421424_gene1791	2.902e-25	115.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,43V3G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GNS2_k127_7474111_4	243231.GSU0349	1.724e-39	153.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GNS2_k127_7474111_10	1274402.JQAJ01000003_gene702	1.435e-09	59.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,47EU1@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
GNS2_k127_7495869_0	404589.Anae109_0703	2.53e-36	143.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GNS2_k127_7495869_1	443144.GM21_3583	2.587e-35	148.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GNS2_k127_7495869_3	1125863.JAFN01000001_gene3051	4.701e-21	108.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
GNS2_k127_7495869_2	1201290.M902_0516	1.165e-32	138.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2MT2P@213481|Bdellovibrionales,2WNAN@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GNS2_k127_7525051_5	243233.MCA0718	2.384e-75	266.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GNS2_k127_7525051_1	1121438.JNJA01000003_gene3264	1.769e-119	400.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2M9PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GNS2_k127_7525051_3	246194.CHY_1128	1.727e-85	301.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,42GBR@68295|Thermoanaerobacterales	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GNS2_k127_7525051_2	378806.STAUR_0696	2.394e-106	354.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YYHJ@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GNS2_k127_7525051_6	1123508.JH636455_gene45	6.411e-60	226.0	COG2234@1|root,COG2234@2|Bacteria,2IZHS@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GNS2_k127_7525051_0	700598.Niako_6711	1.833e-122	404.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IQQ0@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_7525051_4	1192034.CAP_2864	1.414e-84	291.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42NBA@68525|delta/epsilon subdivisions,2X5CP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_7525051_7	391008.Smal_1298	2.198e-06	52.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1X5W6@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23
GNS2_k127_7532323_0	204669.Acid345_1995	1.645e-147	479.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GNS2_k127_7532323_2	880072.Desac_2292	6.459e-35	135.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MQJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GNS2_k127_7532323_3	1122603.ATVI01000010_gene882	0.0003438	43.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,1S654@1236|Gammaproteobacteria,1XC4R@135614|Xanthomonadales	135614|Xanthomonadales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GNS2_k127_7532323_1	1173025.GEI7407_1871	1.284e-38	160.0	COG2367@1|root,COG2367@2|Bacteria,1G1KE@1117|Cyanobacteria,1HAFG@1150|Oscillatoriales	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
GNS2_k127_7544050_3	1415780.JPOG01000001_gene1608	5.205e-30	123.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1S44I@1236|Gammaproteobacteria,1X3DU@135614|Xanthomonadales	135614|Xanthomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GNS2_k127_7544050_5	1123371.ATXH01000006_gene859	4.581e-22	104.0	COG0720@1|root,COG0720@2|Bacteria,2GHTY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GNS2_k127_7544050_0	330214.NIDE0244	1.064e-79	271.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
GNS2_k127_7544050_1	1123371.ATXH01000001_gene1225	7.744e-78	276.0	COG0603@1|root,COG0603@2|Bacteria,2GHPZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
GNS2_k127_7544050_9	489825.LYNGBM3L_39400	0.0001553	53.0	COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria,1H8AK@1150|Oscillatoriales	1117|Cyanobacteria	K	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
GNS2_k127_7544050_2	671143.DAMO_2290	1.709e-55	210.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GNS2_k127_7544050_7	378806.STAUR_7112	1.148e-14	81.0	COG0642@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C0N@68525|delta/epsilon subdivisions,2X7B9@28221|Deltaproteobacteria,2Z3EZ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
GNS2_k127_7544050_4	404589.Anae109_0066	1.197e-22	109.0	COG0705@1|root,COG0705@2|Bacteria,1PD2F@1224|Proteobacteria,42XIJ@68525|delta/epsilon subdivisions,2WT8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Eukaryotic integral membrane protein (DUF1751)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GNS2_k127_7544050_6	246197.MXAN_3112	2.022e-20	97.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42UNA@68525|delta/epsilon subdivisions,2WQ1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	DivIVA protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
GNS2_k127_7544050_8	644282.Deba_0928	2.188e-14	75.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GNS2_k127_7548993_6	760568.Desku_3411	2.437e-07	56.0	COG5662@1|root,COG5662@2|Bacteria,1VC8Y@1239|Firmicutes,24NRN@186801|Clostridia,265G7@186807|Peptococcaceae	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
GNS2_k127_7548993_4	429009.Adeg_0089	1.469e-28	123.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42GIC@68295|Thermoanaerobacterales	186801|Clostridia	K	RNA polymerase sigma factor	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_7548993_3	588932.JHOF01000027_gene1613	5.268e-39	155.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
GNS2_k127_7548993_5	278963.ATWD01000001_gene1480	1.212e-12	79.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
GNS2_k127_7548993_0	204669.Acid345_3439	1.11e-118	403.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
GNS2_k127_7548993_2	1131730.BAVI_17402	2.87e-40	159.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,1ZFJ9@1386|Bacillus	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
GNS2_k127_7548993_1	1123368.AUIS01000005_gene362	1.239e-53	207.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1SND9@1236|Gammaproteobacteria,2NCBR@225057|Acidithiobacillales	225057|Acidithiobacillales	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GNS2_k127_7562932_1	278963.ATWD01000001_gene2440	1.603e-77	274.0	COG1538@1|root,COG1538@2|Bacteria,3Y6KZ@57723|Acidobacteria,2JMBT@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
GNS2_k127_7562932_0	1340493.JNIF01000004_gene458	2.887e-162	523.0	COG2132@1|root,COG2132@2|Bacteria,3Y5PP@57723|Acidobacteria	57723|Acidobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
GNS2_k127_7562932_3	1469613.JT55_16070	3.419e-48	198.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GNS2_k127_7562932_2	1198232.CYCME_1452	2.764e-49	192.0	COG0673@1|root,COG0673@2|Bacteria,1R8B2@1224|Proteobacteria	1224|Proteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GNS2_k127_7562932_4	1198232.CYCME_1442	2.728e-22	98.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GNS2_k127_7570705_0	1267533.KB906733_gene2989	1.988e-93	325.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GNS2_k127_7570705_1	1267533.KB906733_gene2988	3.63e-84	310.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_7589154_4	1499967.BAYZ01000069_gene1878	5.59e-81	278.0	COG1159@1|root,COG1159@2|Bacteria,2NP0U@2323|unclassified Bacteria	2|Bacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595,ko:K06883	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
GNS2_k127_7589154_6	443143.GM18_3495	2.487e-46	187.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
GNS2_k127_7589154_8	1267533.KB906733_gene3065	2.886e-29	123.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GNS2_k127_7589154_3	1340493.JNIF01000003_gene4116	2.862e-113	375.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
GNS2_k127_7589154_5	580332.Slit_2572	1.273e-56	205.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7589154_10	330214.NIDE1351	2.599e-05	56.0	COG3168@1|root,COG3168@2|Bacteria,3J1AT@40117|Nitrospirae	40117|Nitrospirae	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
GNS2_k127_7589154_9	530564.Psta_2346	3.675e-21	106.0	COG1476@1|root,COG1476@2|Bacteria,2J1I8@203682|Planctomycetes	203682|Planctomycetes	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7589154_7	1121920.AUAU01000030_gene2713	4.928e-45	166.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7589154_2	1121920.AUAU01000013_gene1714	3.906e-123	407.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GNS2_k127_7589154_1	1121920.AUAU01000013_gene1713	9.814e-139	452.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_7589154_0	1121920.AUAU01000013_gene1712	6.216e-157	540.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_7614803_2	644966.Tmar_0865	2.224e-146	479.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GNS2_k127_7614803_7	644966.Tmar_0866	5.467e-91	333.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WCHQ@538999|Clostridiales incertae sedis	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GNS2_k127_7614803_4	331869.BAL199_04904	2.96e-120	396.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,4BP7F@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GNS2_k127_7614803_5	639030.JHVA01000001_gene1386	2.047e-108	366.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GNS2_k127_7614803_6	1267534.KB906754_gene2732	1.103e-98	342.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GNS2_k127_7614803_8	1278073.MYSTI_06194	1.381e-87	301.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GNS2_k127_7614803_0	443144.GM21_0509	4.276e-166	533.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GNS2_k127_7614803_9	234267.Acid_7309	1.842e-18	100.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
GNS2_k127_7614803_1	443143.GM18_3882	3.178e-153	494.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GNS2_k127_7614803_3	1267533.KB906733_gene3388	1.181e-121	403.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria,2JHRJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GNS2_k127_76182_10	404589.Anae109_0249	6.561e-18	85.0	COG1277@1|root,COG1277@2|Bacteria,1PK2D@1224|Proteobacteria,437V7@68525|delta/epsilon subdivisions,2WWIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
GNS2_k127_76182_7	869210.Marky_1840	1.992e-48	186.0	294HY@1|root,2ZRXK@2|Bacteria,1WK25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
GNS2_k127_76182_2	640510.BC1001_4272	1.91e-152	489.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_76182_8	756272.Plabr_4030	3.997e-45	168.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GNS2_k127_76182_0	234267.Acid_6747	1.112e-249	781.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
GNS2_k127_76182_9	243233.MCA0706	7.409e-38	143.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XFAE@135618|Methylococcales	135618|Methylococcales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GNS2_k127_76182_1	861299.J421_4258	4.715e-175	560.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
GNS2_k127_76182_5	861299.J421_0616	1.221e-108	364.0	COG0272@1|root,COG0515@1|root,COG0272@2|Bacteria,COG0515@2|Bacteria	2|Bacteria	KLT	protein kinase activity	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	2.7.7.7,6.5.1.2	ko:K01972,ko:K02342,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378,R00382	RC00005,RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,DNA_processg_A,HHH_2,HHH_5,RNase_T
GNS2_k127_76182_4	246197.MXAN_1770	1.85e-113	374.0	COG1388@1|root,COG1388@2|Bacteria,1MY1S@1224|Proteobacteria	1224|Proteobacteria	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
GNS2_k127_76182_3	861299.J421_1844	1.626e-125	413.0	COG2059@1|root,COG2059@2|Bacteria	2|Bacteria	P	chromate transport	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GNS2_k127_76182_11	1278073.MYSTI_06635	7.937e-06	57.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_76182_6	861299.J421_1374	3.484e-65	228.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd2	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
GNS2_k127_7626248_0	234267.Acid_3413	2.183e-144	467.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_7626248_1	1047013.AQSP01000072_gene986	8.993e-76	261.0	COG5000@1|root,COG5000@2|Bacteria,2NQRV@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	ntrY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
GNS2_k127_764776_2	760568.Desku_2792	8.949e-67	250.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,24AKI@186801|Clostridia,263E3@186807|Peptococcaceae	186801|Clostridia	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GNS2_k127_764776_1	706587.Desti_4238	2.058e-159	513.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GNS2_k127_764776_0	945713.IALB_0026	1.292e-171	548.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
GNS2_k127_764776_3	43989.cce_1171	2.402e-28	119.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,3KGMC@43988|Cyanothece	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
GNS2_k127_7657613_6	290397.Adeh_1565	6.771e-58	211.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2YYYV@29|Myxococcales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GNS2_k127_7657613_3	671143.DAMO_0822	2.325e-94	324.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
GNS2_k127_7657613_2	1379698.RBG1_1C00001G0780	6.295e-140	454.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
GNS2_k127_7657613_7	671143.DAMO_0820	1.08e-43	168.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
GNS2_k127_7657613_9	443144.GM21_0398	4.348e-40	172.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Ail_Lom,MtrB_PioB
GNS2_k127_7657613_4	1120956.JHZK01000001_gene3184	3.672e-67	241.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2TZ0I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GNS2_k127_7657613_0	1121920.AUAU01000018_gene1826	5.623e-180	576.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
GNS2_k127_7657613_12	305900.GV64_09435	3.738e-28	124.0	COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,1XMRX@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GNS2_k127_7657613_16	519989.ECTPHS_12575	3.432e-20	101.0	COG0589@1|root,COG0589@2|Bacteria,1NBKV@1224|Proteobacteria,1SHMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
GNS2_k127_7657613_15	926690.KE386573_gene1979	1.749e-23	112.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23SZU@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Usp
GNS2_k127_7657613_17	258594.RPA1220	1.973e-06	58.0	COG0517@1|root,COG0517@2|Bacteria,1R3D7@1224|Proteobacteria,2U6Z7@28211|Alphaproteobacteria,3JRTN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GNS2_k127_7657613_11	416348.Hlac_1706	8.73e-33	138.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23SZU@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Usp
GNS2_k127_7657613_14	330214.NIDE3836	1.103e-26	119.0	COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	prhJ	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GNS2_k127_7657613_1	290397.Adeh_1326	4.612e-155	520.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_7657613_5	290397.Adeh_0418	7.504e-65	244.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
GNS2_k127_7657613_13	1230457.C476_03743	7.956e-28	125.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GNS2_k127_7657613_10	1297742.A176_05886	4.961e-40	154.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Thioredoxin_4,VKOR
GNS2_k127_7665525_4	945713.IALB_2722	8.329e-13	75.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7665525_0	1379698.RBG1_1C00001G0679	4.855e-239	751.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GNS2_k127_7665525_5	706587.Desti_3767	0.0001622	51.0	2CH0Y@1|root,3309M@2|Bacteria,1NF9M@1224|Proteobacteria,42VBP@68525|delta/epsilon subdivisions,2WRWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7665525_2	533247.CRD_02150	4.169e-22	109.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
GNS2_k127_7665525_1	748247.AZKH_1492	1.539e-163	533.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GNS2_k127_7665525_3	1144275.COCOR_02485	2.525e-19	97.0	2BS7F@1|root,32M8R@2|Bacteria,1Q33Y@1224|Proteobacteria,433XP@68525|delta/epsilon subdivisions,2X2HG@28221|Deltaproteobacteria,2YXTX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7680166_1	865937.Gilli_2952	7.072e-50	189.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1I29Z@117743|Flavobacteriia,2P6NA@244698|Gillisia	976|Bacteroidetes	F	Phosphoribosyl transferase domain	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GNS2_k127_7680166_4	648996.Theam_0353	1.574e-16	87.0	COG1254@1|root,COG1254@2|Bacteria,2G49Q@200783|Aquificae	200783|Aquificae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GNS2_k127_7680166_0	357808.RoseRS_0914	1.526e-55	209.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GNS2_k127_7680166_2	882.DVU_0940	8.533e-37	154.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42T0Q@68525|delta/epsilon subdivisions,2WUA0@28221|Deltaproteobacteria,2MB3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,Response_reg
GNS2_k127_7680166_3	1047013.AQSP01000079_gene2043	6.379e-36	150.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
GNS2_k127_7680166_5	2340.JV46_03230	3.61e-06	53.0	COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,1SBPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GNS2_k127_7689166_2	479434.Sthe_1762	5.741e-46	182.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7689166_0	671143.DAMO_1619	7.484e-253	793.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
GNS2_k127_7689166_1	671143.DAMO_1620	7.338e-139	476.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GNS2_k127_7736375_1	945713.IALB_1403	1.84e-123	399.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GNS2_k127_7736375_0	748280.NH8B_0760	1.797e-125	417.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria,2KQAW@206351|Neisseriales	206351|Neisseriales	M	Nitrite reductase, copper-dependent	nirK	-	1.3.3.5,1.7.2.1	ko:K00368,ko:K08100	ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120	M00529	R00783,R00785,R02394	RC00086,RC01983	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3
GNS2_k127_7736375_5	204669.Acid345_3995	4.913e-23	107.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria,2JJ9R@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GNS2_k127_7736375_4	234267.Acid_5438	2.086e-25	122.0	COG1462@1|root,COG1462@2|Bacteria,3Y3KF@57723|Acidobacteria	57723|Acidobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
GNS2_k127_7736375_2	479434.Sthe_1709	1.872e-76	268.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi,27XSE@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C
GNS2_k127_7736375_10	546274.EIKCOROL_00260	1.807e-05	54.0	2C36E@1|root,32RBP@2|Bacteria,1RHA0@1224|Proteobacteria,2VSMY@28216|Betaproteobacteria,2KREY@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7736375_3	1540221.JQNI01000002_gene714	5.035e-43	167.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GNS2_k127_7736375_8	1265503.KB905166_gene681	3.034e-16	93.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	1.17.99.6	ko:K07058,ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Virul_fac_BrkB
GNS2_k127_7736375_7	330214.NIDE3327	2.169e-16	91.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GNS2_k127_7736375_6	194439.CT1218	3.207e-22	104.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
GNS2_k127_7743492_0	211114.JOEF01000003_gene3143	3.524e-74	267.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria,4E24R@85010|Pseudonocardiales	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TAT_signal
GNS2_k127_7743492_1	1122963.AUHB01000019_gene43	5.996e-06	56.0	COG1653@1|root,COG1653@2|Bacteria,1NQQ8@1224|Proteobacteria,2UP76@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
GNS2_k127_7756203_2	525897.Dbac_2593	9.942e-33	136.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MC3Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
GNS2_k127_7756203_3	404589.Anae109_2435	2.741e-13	71.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GNS2_k127_7756203_1	1125863.JAFN01000001_gene1414	1.447e-66	251.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
GNS2_k127_7756203_4	1457250.BBMO01000002_gene2443	3.416e-12	68.0	arCOG01588@1|root,arCOG01588@2157|Archaea,2XZWS@28890|Euryarchaeota,23XIE@183963|Halobacteria	183963|Halobacteria	E	lysine biosynthesis protein LysW	argW	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
GNS2_k127_7756203_0	518766.Rmar_2366	2.33e-94	319.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GNS2_k127_776451_2	983920.Y88_2515	1.034e-09	70.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2USPP@28211|Alphaproteobacteria,2K8AC@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_776451_0	472759.Nhal_3675	2.391e-59	219.0	COG0500@1|root,COG0500@2|Bacteria,1R4KQ@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_776451_1	426355.Mrad2831_1576	1.754e-19	102.0	COG0711@1|root,COG1216@1|root,COG3551@1|root,COG0711@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1QP7Y@1224|Proteobacteria,2TR34@28211|Alphaproteobacteria,1JU9K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF616,Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
GNS2_k127_7765137_1	1166948.JPZL01000001_gene3112	4.558e-176	569.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
GNS2_k127_7765137_5	661478.OP10G_0554	3.801e-41	166.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GNS2_k127_7765137_3	105559.Nwat_0649	2.089e-51	196.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GNS2_k127_7765137_4	251221.35211938	4.163e-50	200.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GNS2_k127_7765137_0	251221.35211937	9.747e-177	586.0	COG0520@1|root,COG0520@2|Bacteria,1G15D@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GNS2_k127_7765137_2	215803.DB30_6994	1.937e-115	388.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2YY27@29|Myxococcales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GNS2_k127_7765137_6	641526.ADIWIN_2652	3.187e-19	87.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia	976|Bacteroidetes	O	Part of SUF system involved in inserting iron-sulfur clusters into proteins	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GNS2_k127_7771219_3	1123368.AUIS01000044_gene15	6.982e-88	307.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GNS2_k127_7771219_6	1088721.NSU_4809	1.404e-53	209.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GNS2_k127_7771219_9	1122611.KB903944_gene1197	1.462e-17	93.0	COG0421@1|root,COG0421@2|Bacteria,2I3HX@201174|Actinobacteria,4EHKS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GNS2_k127_7771219_0	28072.Nos7524_0944	0.0	1273.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1HJRQ@1161|Nostocales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GNS2_k127_7771219_7	1382304.JNIL01000001_gene388	1.196e-39	166.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,279UB@186823|Alicyclobacillaceae	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GNS2_k127_7771219_1	671143.DAMO_0704	2.601e-124	408.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GNS2_k127_7771219_4	420324.KI912071_gene8168	1.095e-77	275.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GNS2_k127_7771219_8	1449049.JONW01000011_gene2311	2.721e-25	119.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7771219_5	1051632.TPY_1556	7.058e-56	208.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WCJJ@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GNS2_k127_7771219_2	1123368.AUIS01000020_gene1095	2.247e-99	336.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,2NCCE@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GNS2_k127_782025_0	1089546.AQUI01000002_gene4363	9.74e-13	81.0	COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,40A17@622450|Actinopolysporales	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7823003_2	1192034.CAP_8276	1.665e-97	349.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GNS2_k127_7823003_4	1313172.YM304_39400	2.405e-11	78.0	COG1357@1|root,COG2834@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG5184@1|root,COG1357@2|Bacteria,COG2834@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,2I7X9@201174|Actinobacteria,4CP5M@84992|Acidimicrobiia	2|Bacteria	DMUZ	Domain of unknown function DUF11	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03634,ko:K13735,ko:K14166,ko:K18491,ko:K20276	ko02024,ko04550,ko05100,map02024,map04550,map05100	-	-	-	ko00000,ko00001,ko02000,ko03000	-	-	-	CarboxypepD_reg,DUF1566
GNS2_k127_7823003_5	1379698.RBG1_1C00001G0758	2.9e-06	58.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7823003_1	204669.Acid345_1065	7.013e-173	569.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GNS2_k127_7823003_0	316274.Haur_0966	5.524e-178	578.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PKD,Reprolysin_4,Reprolysin_5
GNS2_k127_7836887_0	1499967.BAYZ01000178_gene4651	7.738e-84	296.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
GNS2_k127_7849800_6	903818.KI912268_gene2000	3.163e-36	144.0	COG0745@1|root,COG0745@2|Bacteria	903818.KI912268_gene2000|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7849800_3	1047013.AQSP01000083_gene1192	1.487e-152	496.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_7849800_0	204669.Acid345_3357	2.852e-197	648.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
GNS2_k127_7849800_8	1123288.SOV_5c00960	0.0009741	52.0	COG1629@1|root,COG4771@2|Bacteria,1UK28@1239|Firmicutes,4H9AZ@909932|Negativicutes	909932|Negativicutes	P	TonB-dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
GNS2_k127_7849800_4	269799.Gmet_0042	8.823e-53	197.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GNS2_k127_7849800_5	1120958.AULD01000005_gene2151	1.425e-38	160.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4FPPF@85023|Microbacteriaceae	201174|Actinobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GNS2_k127_7849800_2	330214.NIDE1796	3.182e-154	497.0	COG0448@1|root,COG0448@2|Bacteria,3J0BI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GNS2_k127_7849800_1	1340493.JNIF01000003_gene4028	1.053e-183	583.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GNS2_k127_7849800_7	1340493.JNIF01000003_gene2471	2.066e-10	69.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7850128_0	402777.KB235903_gene1792	1.908e-121	408.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HA21@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
GNS2_k127_7850128_2	485913.Krac_8476	5.4e-09	63.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
GNS2_k127_7850128_3	926554.KI912671_gene266	5.238e-07	58.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_3,Cupredoxin_1
GNS2_k127_7850128_1	1304872.JAGC01000003_gene3036	4.976e-12	78.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_7852932_0	1121920.AUAU01000015_gene1127	1.073e-67	253.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
GNS2_k127_7852932_2	439235.Dalk_0743	6.334e-36	151.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GNS2_k127_7852932_1	401053.AciPR4_0272	1.589e-50	186.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria,2JICH@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GNS2_k127_7866539_3	234267.Acid_1488	5.336e-22	100.0	COG3682@1|root,COG3682@2|Bacteria,3Y8QA@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
GNS2_k127_7866539_4	485913.Krac_3882	0.0008948	51.0	2CGCB@1|root,336E3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GNS2_k127_7866539_1	649747.HMPREF0083_01534	3.194e-46	188.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
GNS2_k127_7866539_2	1449049.JONW01000001_gene3326	2.225e-42	176.0	COG0596@1|root,COG0596@2|Bacteria,1NZXA@1224|Proteobacteria,2TY7X@28211|Alphaproteobacteria,2KJGA@204458|Caulobacterales	204458|Caulobacterales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GNS2_k127_7866539_0	857293.CAAU_0043	4.337e-70	240.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
GNS2_k127_7871148_5	1267533.KB906735_gene4843	2.097e-05	54.0	COG5373@1|root,COG5373@2|Bacteria,3Y7N9@57723|Acidobacteria,2JMVJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GNS2_k127_7871148_3	880073.Calab_1912	1.395e-70	250.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GNS2_k127_7871148_0	555079.Toce_1246	3.72e-193	632.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GNS2_k127_7871148_1	765869.BDW_11285	2.687e-125	410.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2MTGD@213481|Bdellovibrionales,2WJI0@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GNS2_k127_7871148_2	1379698.RBG1_1C00001G0361	1.35e-109	378.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GNS2_k127_7871148_4	204669.Acid345_2250	8.773e-56	204.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria,2JHJ5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GNS2_k127_7895843_0	234267.Acid_3259	4.389e-257	803.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GNS2_k127_7895843_1	204669.Acid345_2436	1.484e-192	610.0	28IJB@1|root,2Z8K8@2|Bacteria,3Y62T@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7895843_5	96561.Dole_0148	1.565e-60	231.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GNS2_k127_7895843_4	1379270.AUXF01000004_gene3068	1.14e-83	287.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_7895843_3	379066.GAU_0825	1.159e-86	310.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
GNS2_k127_7895843_7	204669.Acid345_2637	4.918e-11	65.0	COG2161@1|root,COG2161@2|Bacteria,3Y5VX@57723|Acidobacteria,2JK4M@204432|Acidobacteriia	204432|Acidobacteriia	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
GNS2_k127_7895843_2	1267535.KB906767_gene4838	3.798e-108	377.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GNS2_k127_7928442_13	285535.JOEY01000096_gene3195	4.459e-35	143.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria	201174|Actinobacteria	DM	biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA,Wzz
GNS2_k127_7928442_6	536232.CLM_0191	6.757e-73	273.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,36F6R@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GNS2_k127_7928442_0	1123368.AUIS01000027_gene1355	8.739e-201	646.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GNS2_k127_7928442_2	760192.Halhy_2892	3.665e-124	421.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1IR5W@117747|Sphingobacteriia	976|Bacteroidetes	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GNS2_k127_7928442_11	521011.Mpal_0351	5.044e-40	171.0	COG2006@1|root,arCOG02447@2157|Archaea,2XWUP@28890|Euryarchaeota,2NB6D@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GNS2_k127_7928442_14	1396418.BATQ01000166_gene1936	7.198e-26	122.0	COG0438@1|root,COG0438@2|Bacteria,46VET@74201|Verrucomicrobia,2IUKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
GNS2_k127_7928442_12	748247.AZKH_0907	1.942e-37	163.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_7928442_5	1173027.Mic7113_5731	1.14e-89	315.0	28JDY@1|root,2Z987@2|Bacteria,1G20Y@1117|Cyanobacteria,1HAB3@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	O-ag_pol_Wzy
GNS2_k127_7928442_7	1125863.JAFN01000001_gene3034	1.472e-63	237.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
GNS2_k127_7928442_1	1123508.JH636440_gene2608	2.445e-130	441.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
GNS2_k127_7928442_4	391625.PPSIR1_34113	2.852e-101	344.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
GNS2_k127_7928442_9	234267.Acid_5241	1.62e-54	202.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7928442_18	278963.ATWD01000001_gene4374	5.099e-07	54.0	COG0848@1|root,COG0848@2|Bacteria,3Y4QV@57723|Acidobacteria,2JJ9P@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
GNS2_k127_7928442_16	1340493.JNIF01000003_gene1849	3.461e-19	103.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
GNS2_k127_7928442_8	479434.Sthe_1323	6.248e-58	218.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GNS2_k127_7928442_10	1047013.AQSP01000138_gene1062	1.716e-47	188.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
GNS2_k127_7928442_3	234267.Acid_7731	3.896e-109	358.0	COG2022@1|root,COG2022@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
GNS2_k127_7928442_17	1408419.JHYG01000002_gene1113	2.536e-14	76.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2UMNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GNS2_k127_7928442_15	903818.KI912269_gene353	7.964e-23	104.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_7952064_2	671143.DAMO_1345	7.897e-71	253.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
GNS2_k127_7952064_1	234267.Acid_1761	1.266e-129	431.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria	57723|Acidobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GNS2_k127_7952064_3	1267535.KB906767_gene5001	1.748e-43	182.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GNS2_k127_7952064_0	234267.Acid_6511	4.583e-168	548.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria	57723|Acidobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GNS2_k127_7952064_4	309807.SRU_0371	1.957e-17	84.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GNS2_k127_8000029_0	861299.J421_1502	0.0	1337.0	COG4447@1|root,COG4447@2|Bacteria,1ZUS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GNS2_k127_8000029_1	215803.DB30_3835	8.431e-21	97.0	28QQ1@1|root,2ZD5J@2|Bacteria,1QPY8@1224|Proteobacteria,439MX@68525|delta/epsilon subdivisions,2X4Z5@28221|Deltaproteobacteria,2YZVK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8000029_2	1121123.AUAO01000001_gene1046	1.57e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,2KF8Y@204458|Caulobacterales	204458|Caulobacterales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_8000269_8	1278073.MYSTI_02763	2.203e-34	138.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_8000269_9	771875.Ferpe_0714	2.057e-29	136.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GNS2_k127_8000269_4	32057.KB217478_gene6272	1.951e-147	475.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,1HM9D@1161|Nostocales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GNS2_k127_8000269_11	1396141.BATP01000027_gene1078	5.028e-06	58.0	arCOG05203@1|root,31A0K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8000269_10	1033730.CAHG01000007_gene2812	2.13e-09	68.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4DQN9@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GNS2_k127_8000269_6	1121405.dsmv_1698	1.359e-98	335.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2MKQU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
GNS2_k127_8000269_0	497964.CfE428DRAFT_2129	0.0	1373.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GNS2_k127_8000269_5	204669.Acid345_1475	2.239e-110	386.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GNS2_k127_8000269_3	204669.Acid345_1474	5.431e-148	480.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GNS2_k127_8000269_7	694427.Palpr_1308	2.129e-94	323.0	2ET12@1|root,33KJA@2|Bacteria,4P2T4@976|Bacteroidetes	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	OmpA_membrane,PagL
GNS2_k127_8000269_1	1078020.KEK_20583	0.0	1036.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
GNS2_k127_8000269_2	1121920.AUAU01000013_gene1698	5.36e-293	909.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
GNS2_k127_8008944_6	1121920.AUAU01000018_gene1797	1.124e-07	62.0	COG0477@1|root,COG2814@2|Bacteria,3Y95Q@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GNS2_k127_8008944_1	926550.CLDAP_38230	2.372e-122	418.0	COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
GNS2_k127_8008944_0	661478.OP10G_1068	2.362e-139	453.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
GNS2_k127_8008944_5	240015.ACP_1605	2.34e-27	123.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJBQ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GNS2_k127_8008944_3	240015.ACP_1606	6.688e-50	197.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria,2JIYJ@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GNS2_k127_8008944_4	290397.Adeh_2610	7.769e-48	191.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GNS2_k127_8008944_2	1047013.AQSP01000111_gene1672	2.517e-82	286.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
GNS2_k127_8019283_1	118163.Ple7327_0425	3.014e-79	270.0	COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GNS2_k127_8019283_0	204669.Acid345_2236	5.335e-142	470.0	COG1052@1|root,COG1052@2|Bacteria,3Y8C1@57723|Acidobacteria,2JNCS@204432|Acidobacteriia	204432|Acidobacteriia	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GNS2_k127_8019283_3	1121933.AUHH01000024_gene2969	2.014e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,2GXH4@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_8
GNS2_k127_8019283_2	215803.DB30_3073	1.467e-08	68.0	COG0726@1|root,COG4319@1|root,COG0726@2|Bacteria,COG4319@2|Bacteria,1RFCG@1224|Proteobacteria,43BYQ@68525|delta/epsilon subdivisions,2X79K@28221|Deltaproteobacteria,2Z21H@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GNS2_k127_8028249_1	671143.DAMO_2838	1.76e-108	381.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GNS2_k127_8028249_0	1121033.AUCF01000001_gene2157	4.177e-131	449.0	COG3392@1|root,COG3392@2|Bacteria,1QYMW@1224|Proteobacteria,2U3VQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223,ko:K07318	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
GNS2_k127_8028249_2	1134912.AJTV01000002_gene1748	8.289e-48	181.0	2AC8B@1|root,311T0@2|Bacteria,1NK0P@1224|Proteobacteria,2VD5M@28211|Alphaproteobacteria,3713U@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_805210_9	518766.Rmar_2231	4.455e-49	185.0	COG3228@1|root,COG3228@2|Bacteria,4NGM9@976|Bacteroidetes,1FJ6P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
GNS2_k127_805210_8	575540.Isop_0496	4.885e-59	221.0	COG0564@1|root,COG0564@2|Bacteria,2J01R@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GNS2_k127_805210_4	234267.Acid_1535	7.526e-87	306.0	COG0739@1|root,COG0739@2|Bacteria,3Y3GS@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GNS2_k127_805210_12	1121396.KB893074_gene3027	1.507e-08	66.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,42TZW@68525|delta/epsilon subdivisions,2WNUV@28221|Deltaproteobacteria,2MMRU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GNS2_k127_805210_13	1232410.KI421421_gene3474	0.0002533	49.0	COG3215@1|root,COG3215@2|Bacteria,1NW7J@1224|Proteobacteria,43C0W@68525|delta/epsilon subdivisions,2WVFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GNS2_k127_805210_1	1125863.JAFN01000001_gene332	4.93e-114	384.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_805210_2	1210884.HG799463_gene9943	1.898e-95	323.0	COG1226@1|root,COG1226@2|Bacteria,2IYAZ@203682|Planctomycetes	203682|Planctomycetes	P	K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
GNS2_k127_805210_0	518766.Rmar_2008	1.4e-196	623.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GNS2_k127_805210_5	314345.SPV1_12687	4.29e-76	261.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria	1224|Proteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_805210_7	1267535.KB906767_gene3271	3.338e-61	229.0	COG5002@1|root,COG5002@2|Bacteria,3Y97Y@57723|Acidobacteria,2JP4Q@204432|Acidobacteriia	204432|Acidobacteriia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GNS2_k127_805210_3	159087.Daro_1402	1.728e-91	317.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria,2KUB7@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GNS2_k127_805210_6	395494.Galf_2003	3.818e-73	280.0	COG0653@1|root,COG0653@2|Bacteria,1QWG7@1224|Proteobacteria,2VPIK@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
GNS2_k127_805477_0	323259.Mhun_1465	2.635e-89	302.0	COG0205@1|root,arCOG03641@2157|Archaea	2157|Archaea	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GNS2_k127_805477_2	443143.GM18_2614	7.435e-27	120.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GNS2_k127_805477_3	1121448.DGI_0333	5.506e-23	112.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,2MCBQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GNS2_k127_805477_4	204669.Acid345_2361	1.584e-09	62.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria,2JNW9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
GNS2_k127_805477_1	1131269.AQVV01000018_gene1893	3.782e-47	177.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
GNS2_k127_8062154_1	639030.JHVA01000001_gene3891	2.836e-72	263.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GNS2_k127_8062154_5	596152.DesU5LDRAFT_0052	3.808e-29	130.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,2MAGK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GNS2_k127_8062154_0	379066.GAU_0238	1.911e-77	286.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_8062154_4	671143.DAMO_2591	1.94e-35	153.0	2E0UX@1|root,32WC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
GNS2_k127_8062154_3	1174528.JH992898_gene3099	6.563e-55	223.0	COG4485@1|root,COG4485@2|Bacteria,1GGV1@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8062154_6	383372.Rcas_3354	2.53e-16	95.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GNS2_k127_8062154_7	298654.FraEuI1c_2129	5.269e-09	70.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
GNS2_k127_8062154_2	479434.Sthe_0904	3.136e-67	248.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_8062154_8	316274.Haur_4277	2.971e-06	55.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi,375X4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_807949_4	498761.HM1_3053	1.063e-67	244.0	COG0124@1|root,COG0124@2|Bacteria,1UIUT@1239|Firmicutes,25ESP@186801|Clostridia	186801|Clostridia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
GNS2_k127_807949_7	1125863.JAFN01000001_gene1722	2.051e-51	201.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WNAZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
GNS2_k127_807949_1	671143.DAMO_2245	9.805e-82	302.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14140,iYO844.BSU34910	Histidinol_dh
GNS2_k127_807949_3	290318.Cvib_0754	3.145e-69	263.0	COG0079@1|root,COG0079@2|Bacteria,1FDRG@1090|Chlorobi	1090|Chlorobi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GNS2_k127_807949_2	1286106.MPL1_03183	3.568e-71	246.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,45ZPZ@72273|Thiotrichales	72273|Thiotrichales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
GNS2_k127_807949_6	518766.Rmar_1571	9.183e-60	223.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1FJ7C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GNS2_k127_807949_5	760568.Desku_1689	3.367e-65	240.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,260RZ@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GNS2_k127_807949_0	477974.Daud_1622	9.055e-97	335.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,260VM@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
GNS2_k127_807949_8	1112214.AHIS01000095_gene856	1.622e-30	128.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,2K56R@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
GNS2_k127_8089944_2	1395571.TMS3_0118210	3.138e-13	81.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	ltg	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
GNS2_k127_8089944_1	1042163.BRLA_c017340	1.382e-40	168.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,26WZ2@186822|Paenibacillaceae	91061|Bacilli	L	AdP-ribose pyrophosphatase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
GNS2_k127_8089944_0	1267534.KB906755_gene4489	3.063e-67	238.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GNS2_k127_8120561_0	497964.CfE428DRAFT_3875	7.522e-82	289.0	COG1502@1|root,COG1502@2|Bacteria,46SV9@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GNS2_k127_8120561_1	1379270.AUXF01000003_gene3868	1.323e-19	93.0	2AEWX@1|root,314UJ@2|Bacteria,1ZUPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8145724_1	935948.KE386494_gene260	4.694e-69	241.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GNS2_k127_8145724_0	639282.DEFDS_0119	2.365e-98	338.0	COG0528@1|root,COG0528@2|Bacteria,2GEZE@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GNS2_k127_8145724_2	1304888.ATWF01000002_gene417	1.271e-53	207.0	COG0233@1|root,COG0233@2|Bacteria,2GFEE@200930|Deferribacteres	200930|Deferribacteres	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GNS2_k127_8145724_3	1144275.COCOR_02328	6.367e-38	146.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2Z30A@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GNS2_k127_815148_4	1209072.ALBT01000032_gene2103	9.119e-61	229.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
GNS2_k127_815148_6	1125863.JAFN01000001_gene3329	3.177e-54	209.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
GNS2_k127_815148_2	711393.AYRX01000053_gene5969	4.657e-86	295.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GNS2_k127_815148_5	395494.Galf_1181	5.458e-58	224.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
GNS2_k127_815148_10	1463841.JOIR01000040_gene4622	4.2e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GNS2_k127_815148_3	102129.Lepto7375DRAFT_5494	7.713e-62	228.0	COG0500@1|root,COG2226@2|Bacteria,1G3CH@1117|Cyanobacteria,1HAB6@1150|Oscillatoriales	1117|Cyanobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_815148_9	1123389.ATXJ01000004_gene1243	1.579e-20	97.0	COG0517@1|root,COG0517@2|Bacteria,1WI6I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GNS2_k127_815148_7	941449.dsx2_2908	1.647e-50	191.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MBDA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
GNS2_k127_815148_0	1382359.JIAL01000001_gene2614	6.282e-152	492.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GNS2_k127_815148_1	69014.TK0329	1.896e-94	319.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GNS2_k127_815148_8	387631.Asulf_00513	6.858e-37	149.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,2469B@183980|Archaeoglobi	183980|Archaeoglobi	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GNS2_k127_8155771_5	1121920.AUAU01000001_gene2233	5.147e-11	65.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
GNS2_k127_8155771_3	1415755.JQLV01000001_gene2199	6.027e-47	183.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XI40@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9
GNS2_k127_8155771_1	1268622.AVS7_03016	2.571e-163	538.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,4ACQU@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GNS2_k127_8155771_4	1131269.AQVV01000032_gene312	5.926e-12	77.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_8155771_2	246197.MXAN_3125	1.444e-124	408.0	COG3214@1|root,COG3214@2|Bacteria,1R9AI@1224|Proteobacteria,43400@68525|delta/epsilon subdivisions,2X4C8@28221|Deltaproteobacteria,2YYQU@29|Myxococcales	28221|Deltaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GNS2_k127_8155771_0	365046.Rta_06820	3.862e-179	592.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GNS2_k127_8165579_6	290397.Adeh_2405	4.717e-76	265.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GNS2_k127_8165579_1	404589.Anae109_0240	8.169e-312	969.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
GNS2_k127_8165579_9	500637.PROVRUST_04617	1.477e-35	140.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,1SA64@1236|Gammaproteobacteria,3ZA5M@586|Providencia	1236|Gammaproteobacteria	S	Ethanolamine utilisation protein EutQ	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GNS2_k127_8165579_10	266117.Rxyl_1803	1.194e-31	139.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CPNY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GNS2_k127_8165579_7	648757.Rvan_3596	1.895e-63	223.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PFAM OsmC family protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
GNS2_k127_8165579_2	861299.J421_6016	2.842e-235	758.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8165579_4	84531.JMTZ01000166_gene1251	3.79e-101	344.0	COG0642@1|root,COG2205@2|Bacteria,1R8JB@1224|Proteobacteria,1TBWY@1236|Gammaproteobacteria,1X9E4@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
GNS2_k127_8165579_8	945713.IALB_2899	1.864e-47	176.0	28NYH@1|root,2ZBVN@2|Bacteria	2|Bacteria	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
GNS2_k127_8165579_0	261292.Nit79A3_0036	0.0	1431.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,372DE@32003|Nitrosomonadales	28216|Betaproteobacteria	G	aldehyde-lyase activity	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
GNS2_k127_8165579_5	395965.Msil_0163	7.366e-79	270.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,3NAJT@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GNS2_k127_8165579_3	1266925.JHVX01000002_gene816	2.063e-192	608.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GNS2_k127_8167052_6	266117.Rxyl_2212	1.317e-136	445.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GNS2_k127_8167052_9	292459.STH404	4.653e-83	285.0	COG0702@1|root,COG0702@2|Bacteria,1VEC8@1239|Firmicutes,25BCI@186801|Clostridia	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GNS2_k127_8167052_14	1123255.JHYS01000013_gene65	4.878e-05	52.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,2VPTX@28216|Betaproteobacteria,4AFPP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
GNS2_k127_8167052_5	644282.Deba_1534	2.021e-150	496.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_8167052_11	1304872.JAGC01000003_gene3083	4.491e-65	229.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_8167052_7	330214.NIDE0857	8.565e-105	371.0	COG5002@1|root,COG5002@2|Bacteria,3J0I0@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
GNS2_k127_8167052_0	204669.Acid345_0280	0.0	1071.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,3Y7G5@57723|Acidobacteria	57723|Acidobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
GNS2_k127_8167052_1	945713.IALB_0301	9.117e-248	771.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GNS2_k127_8167052_3	1303518.CCALI_01309	1.219e-182	586.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria	2|Bacteria	C	tartrate metabolic process	fumB	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
GNS2_k127_8167052_12	215803.DB30_0080	2.457e-59	223.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YZ2M@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_8167052_10	1125863.JAFN01000001_gene2110	3.101e-68	238.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GNS2_k127_8167052_8	903818.KI912268_gene980	2.245e-103	367.0	COG1117@1|root,COG1117@2|Bacteria,3Y35A@57723|Acidobacteria	57723|Acidobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GNS2_k127_8167052_4	945713.IALB_1900	3.69e-173	567.0	COG0581@1|root,COG0581@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GNS2_k127_8167052_2	671143.DAMO_1102	1.624e-191	622.0	COG4590@1|root,COG4590@2|Bacteria,2NS4H@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GNS2_k127_8167052_13	247490.KSU1_B0329	4.178e-41	153.0	COG0226@1|root,COG0226@2|Bacteria,2IYX0@203682|Planctomycetes	203682|Planctomycetes	P	COG0226 ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
GNS2_k127_8183081_2	1382356.JQMP01000003_gene1584	6.619e-164	551.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
GNS2_k127_8183081_4	1121920.AUAU01000008_gene1590	8.07e-106	386.0	COG0167@1|root,COG0167@2|Bacteria,3Y464@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GNS2_k127_8183081_0	1121920.AUAU01000008_gene1589	0.0	1667.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,3Y415@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
GNS2_k127_8183081_7	1156937.MFUM_140022	2.734e-10	74.0	COG1764@1|root,COG1764@2|Bacteria,46YZS@74201|Verrucomicrobia,37GVX@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
GNS2_k127_8183081_3	649638.Trad_0672	3.081e-158	516.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,GARS_A,Glu_cys_ligase
GNS2_k127_8183081_1	404589.Anae109_0322	5.75e-167	537.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.14,1.2.1.46	ko:K00008,ko:K00148,ko:K18369	ko00040,ko00051,ko00625,ko00640,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00640,map00680,map01100,map01120,map01200	M00014	R00604,R00875,R01896,R10703	RC00085,RC00102,RC00188,RC00545	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_8183081_5	880072.Desac_1083	6.507e-31	126.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
GNS2_k127_8183081_6	237368.SCABRO_01480	2.358e-11	67.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2IYW3@203682|Planctomycetes	203682|Planctomycetes	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GNS2_k127_8252792_2	204669.Acid345_3833	1.733e-41	161.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8252792_1	1047013.AQSP01000037_gene1322	1.814e-118	398.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294,ko:K13868	ko04974,map04974	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.8.15	-	-	AA_permease_2
GNS2_k127_8252792_0	204669.Acid345_2823	5.319e-155	530.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria,2JI7G@204432|Acidobacteriia	2|Bacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
GNS2_k127_8286692_6	1122947.FR7_3084	0.0001203	51.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4H41A@909932|Negativicutes	909932|Negativicutes	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GNS2_k127_8286692_7	1395571.TMS3_0123180	0.0008503	49.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S91P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GNS2_k127_8286692_0	314278.NB231_16543	1.317e-246	804.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WXK0@135613|Chromatiales	135613|Chromatiales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.28,1.2.1.3	ko:K00128,ko:K00141	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00622,ko00623,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00622,map00623,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00135,M00537,M00538	R00264,R00631,R00710,R00904,R01293,R01419,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05289,R05663,R05664,R06366,R07667,R08146	RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GNS2_k127_8286692_2	398767.Glov_2372	6.82e-169	548.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
GNS2_k127_8286692_4	1379698.RBG1_1C00001G0503	1.095e-50	203.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GNS2_k127_8286692_5	665571.STHERM_c03350	4.148e-35	145.0	COG2078@1|root,COG2078@2|Bacteria,2J7B9@203691|Spirochaetes	203691|Spirochaetes	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
GNS2_k127_8286692_3	335543.Sfum_1996	6.795e-65	232.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
GNS2_k127_8286692_1	290397.Adeh_1076	1.785e-191	612.0	COG1543@1|root,COG1543@2|Bacteria,1R5SN@1224|Proteobacteria,42PSX@68525|delta/epsilon subdivisions,2WU5G@28221|Deltaproteobacteria,2YTTH@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
GNS2_k127_8357810_8	760192.Halhy_5577	6.772e-06	52.0	2ET4W@1|root,33KNZ@2|Bacteria,4P5X3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8357810_1	448385.sce5789	2.21e-187	607.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2YU3G@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GNS2_k127_8357810_7	289376.THEYE_A0045	5.825e-32	134.0	COG4856@1|root,COG4856@2|Bacteria,3J1EE@40117|Nitrospirae	40117|Nitrospirae	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
GNS2_k127_8357810_4	204669.Acid345_0278	1.715e-62	230.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
GNS2_k127_8357810_3	1173028.ANKO01000168_gene4345	5.823e-75	265.0	COG0294@1|root,COG0294@2|Bacteria,1G050@1117|Cyanobacteria,1H8GY@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796,ko:K18824	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Pterin_bind
GNS2_k127_8357810_0	204669.Acid345_0064	3.32e-262	821.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GNS2_k127_8357810_6	580327.Tthe_0360	5.048e-32	144.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42G9G@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GNS2_k127_8357810_5	1232410.KI421415_gene3041	2.663e-61	229.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43S3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	TilS substrate binding domain	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
GNS2_k127_8357810_2	671143.DAMO_2716	6.863e-86	288.0	COG0113@1|root,COG0113@2|Bacteria,2NNST@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ALAD family	hemB	GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477	ALAD
GNS2_k127_8358326_0	981369.JQMJ01000004_gene1390	7.706e-59	216.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,2NGPH@228398|Streptacidiphilus	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GNS2_k127_8358326_1	1385520.N802_04150	5.648e-18	94.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GNS2_k127_8400145_2	66429.JOFL01000029_gene5112	1.219e-20	104.0	COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_8400145_0	1167006.UWK_02410	7.182e-62	240.0	COG1817@1|root,COG1817@2|Bacteria,1NE3M@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
GNS2_k127_8400145_1	925409.KI911562_gene150	1.092e-32	141.0	COG2227@1|root,COG2227@2|Bacteria,4NNQC@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_8413603_3	1357279.N018_24485	2.891e-21	106.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,1S6SU@1236|Gammaproteobacteria,1Z6AI@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
GNS2_k127_8413603_2	945713.IALB_0196	5.9e-35	138.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,Haem_bd,PSD1
GNS2_k127_8413603_0	234267.Acid_0345	1.687e-90	305.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
GNS2_k127_8413603_1	690850.Desaf_1341	3.773e-41	167.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2MCY6@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	HlyD_D23
GNS2_k127_8458130_0	378806.STAUR_4411	0.0	1058.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
GNS2_k127_8458130_6	1128421.JAGA01000002_gene964	1.211e-74	262.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GNS2_k127_8458130_1	1121335.Clst_1477	9.707e-222	716.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
GNS2_k127_8458130_11	1151122.AQYD01000007_gene1247	0.0005167	53.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4FMMM@85023|Microbacteriaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GNS2_k127_8458130_2	1382306.JNIM01000001_gene1323	7.129e-217	707.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GNS2_k127_8458130_10	56780.SYN_00127	0.0001966	51.0	COG0784@1|root,COG0784@2|Bacteria,1RHWK@1224|Proteobacteria,42SCZ@68525|delta/epsilon subdivisions,2WPGH@28221|Deltaproteobacteria,2MSAD@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
GNS2_k127_8458130_4	204669.Acid345_0689	4.56e-127	421.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GNS2_k127_8458130_7	1499967.BAYZ01000016_gene6550	1.495e-64	232.0	COG2326@1|root,COG2326@2|Bacteria	2|Bacteria	S	polyphosphate kinase activity	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
GNS2_k127_8458130_5	313624.NSP_1460	3.946e-87	300.0	COG2326@1|root,COG2326@2|Bacteria,1G34U@1117|Cyanobacteria,1HP25@1161|Nostocales	1117|Cyanobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
GNS2_k127_8458130_8	1037409.BJ6T_32900	3.268e-44	176.0	COG2020@1|root,COG2020@2|Bacteria,1RBJE@1224|Proteobacteria,2U6NI@28211|Alphaproteobacteria,3JYFN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GNS2_k127_8458130_3	1089550.ATTH01000001_gene1831	1.904e-154	511.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
GNS2_k127_8458130_9	411466.ACTODO_01384	5.42e-37	146.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4D3GT@85005|Actinomycetales	201174|Actinobacteria	HP	ABC transporter, ATP-binding protein	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GNS2_k127_849639_1	378806.STAUR_6405	2.643e-185	591.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GNS2_k127_849639_0	869210.Marky_1233	5.099e-207	657.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD
GNS2_k127_849639_6	1128398.Curi_c20910	7.093e-58	227.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,268DI@186813|unclassified Clostridiales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GNS2_k127_849639_2	945713.IALB_1038	1.265e-132	433.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GNS2_k127_849639_3	596152.DesU5LDRAFT_0145	2.141e-132	445.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
GNS2_k127_849639_4	1033802.SSPSH_000464	2.499e-96	336.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GNS2_k127_849639_5	84531.JMTZ01000003_gene2339	4.757e-87	303.0	COG0730@1|root,COG0730@2|Bacteria,1R6MR@1224|Proteobacteria,1S0QW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
GNS2_k127_849639_7	1254432.SCE1572_44010	1.298e-22	106.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
GNS2_k127_849639_8	661367.LLO_2152	4.189e-12	71.0	COG2314@1|root,COG4640@1|root,COG2314@2|Bacteria,COG4640@2|Bacteria,1N8CV@1224|Proteobacteria,1T0FD@1236|Gammaproteobacteria,1JE4I@118969|Legionellales	118969|Legionellales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864,TM2,zinc_ribbon_2
GNS2_k127_8501020_2	926569.ANT_28190	3.847e-45	177.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	Apolipoprotein,RmuC
GNS2_k127_8501020_0	1121346.KB899821_gene2714	1.195e-62	226.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,26QSG@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyisobutyrate dehydrogenase	hopR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2,PilZ
GNS2_k127_8501020_1	671143.DAMO_2896	7.36e-61	218.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GNS2_k127_8517230_1	886293.Sinac_6333	9.561e-36	153.0	COG1807@1|root,COG1807@2|Bacteria,2J2F6@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8517230_0	330214.NIDE2879	4.024e-45	183.0	2DM57@1|root,31S0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8517230_2	401053.AciPR4_2703	1.426e-14	87.0	2DVRE@1|root,33WVZ@2|Bacteria,3Y60B@57723|Acidobacteria,2JMWX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8522813_2	1191523.MROS_2376	6.221e-75	258.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GNS2_k127_8522813_1	880073.Calab_2689	3.32e-100	339.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GNS2_k127_8522813_3	880073.Calab_2688	3.54e-38	163.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K03615,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
GNS2_k127_8522813_4	331678.Cphamn1_1601	1.146e-34	143.0	COG0839@1|root,COG0839@2|Bacteria,1FDZK@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GNS2_k127_8522813_5	635013.TherJR_2031	2.834e-29	119.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,24NKG@186801|Clostridia,262H1@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GNS2_k127_8522813_0	290397.Adeh_2581	1.431e-117	399.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GNS2_k127_8522813_6	323848.Nmul_A1969	3.626e-14	76.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
GNS2_k127_8524300_3	1157632.AQWQ01000005_gene1119	1.031e-18	90.0	COG0702@1|root,COG0702@2|Bacteria,2HBFK@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GNS2_k127_8524300_0	1463901.JOIY01000044_gene172	2.263e-74	254.0	COG0702@1|root,COG0702@2|Bacteria,2HBFK@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GNS2_k127_8524300_5	1316936.K678_05843	1.003e-05	50.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2JPJ7@204441|Rhodospirillales	204441|Rhodospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
GNS2_k127_8524300_1	861299.J421_4375	1.015e-49	185.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_8524300_4	1300345.LF41_960	1.125e-07	64.0	2CKCT@1|root,32SC5@2|Bacteria,1N1BJ@1224|Proteobacteria,1T6U5@1236|Gammaproteobacteria,1X85I@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8524300_2	1442599.JAAN01000015_gene3199	2.047e-31	141.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GNS2_k127_8545758_3	1229780.BN381_310099	1.08e-12	81.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
GNS2_k127_8545758_1	991905.SL003B_2331	4.971e-64	244.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,4BQ9P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GNS2_k127_8545758_0	383372.Rcas_1635	3.543e-202	642.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
GNS2_k127_8545840_1	314278.NB231_06775	6.425e-35	138.0	COG1017@1|root,COG1017@2|Bacteria,1NA56@1224|Proteobacteria,1SDRC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitric oxide dioxygenase activity	VPA1107	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8545840_0	926566.Terro_3306	1.571e-55	206.0	COG0526@1|root,COG0526@2|Bacteria,3Y5H5@57723|Acidobacteria,2JMSM@204432|Acidobacteriia	204432|Acidobacteriia	CO	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
GNS2_k127_8545840_3	234267.Acid_0082	3.119e-20	100.0	2FE51@1|root,3464Y@2|Bacteria,3Y8E0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8545840_2	236814.IX39_13550	1.443e-28	126.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,3ZQ15@59732|Chryseobacterium	976|Bacteroidetes	Q	Mammalian cell entry protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
GNS2_k127_8571362_0	215803.DB30_7162	2.429e-245	790.0	COG3962@1|root,COG3962@2|Bacteria,1QX94@1224|Proteobacteria,43C26@68525|delta/epsilon subdivisions,2X7CR@28221|Deltaproteobacteria,2YYEC@29|Myxococcales	28221|Deltaproteobacteria	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GNS2_k127_8571362_1	215803.DB30_7163	1.463e-106	364.0	COG3718@1|root,COG3718@2|Bacteria,1MWGD@1224|Proteobacteria,42VSE@68525|delta/epsilon subdivisions,2WRJ3@28221|Deltaproteobacteria,2YY72@29|Myxococcales	28221|Deltaproteobacteria	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
GNS2_k127_8571362_2	1380391.JIAS01000013_gene3753	7.135e-18	93.0	COG0673@1|root,COG0673@2|Bacteria,1R4NJ@1224|Proteobacteria,2U4PN@28211|Alphaproteobacteria,2JXR6@204441|Rhodospirillales	204441|Rhodospirillales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
GNS2_k127_8609630_3	357808.RoseRS_0852	7.403e-15	87.0	COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2G9FD@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16,TPR_8
GNS2_k127_8609630_1	1267535.KB906767_gene5001	7.947e-65	250.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
GNS2_k127_8609630_2	234267.Acid_5253	1.348e-46	181.0	COG0546@1|root,COG0546@2|Bacteria,3Y4RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GNS2_k127_8609630_0	204669.Acid345_4432	1.674e-162	535.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
GNS2_k127_8626718_7	204669.Acid345_3636	0.000139	54.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
GNS2_k127_8626718_0	357808.RoseRS_3778	2.012e-84	291.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,374SY@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GNS2_k127_8626718_3	1382359.JIAL01000001_gene1949	3.222e-45	168.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GNS2_k127_8626718_4	345219.Bcoa_0176	2.667e-29	123.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GNS2_k127_8626718_1	1242864.D187_005833	2.307e-81	288.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
GNS2_k127_8626718_5	404380.Gbem_3412	4.296e-29	132.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GNS2_k127_8626718_6	1499967.BAYZ01000076_gene833	4.438e-16	86.0	COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cytochrom_C
GNS2_k127_8626718_2	926560.KE387023_gene3140	2.653e-59	213.0	COG1473@1|root,COG1473@2|Bacteria,1WM7N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GNS2_k127_8652600_1	234267.Acid_7185	4.811e-133	471.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8652600_2	1047013.AQSP01000140_gene2527	1.517e-105	364.0	COG1044@1|root,COG1044@2|Bacteria,2NQT1@2323|unclassified Bacteria	2|Bacteria	M	SpoIVB peptidase S55	-	-	2.7.7.24	ko:K00973,ko:K02414,ko:K21449	ko00521,ko00523,ko00525,ko01130,ko02040,map00521,map00523,map00525,map01130,map02040	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035	1.B.40.2	-	-	AMP-binding,APH,DUF4114,DUF4842,Hexapep,PP-binding,Peptidase_S55
GNS2_k127_8652600_0	72019.SARC_04648T0	1.183e-161	527.0	COG0281@1|root,KOG1257@2759|Eukaryota,3A9RX@33154|Opisthokonta	33154|Opisthokonta	C	malate dehydrogenase (decarboxylating) (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Malic_M,PTA_PTB,Peptidase_M48,malic
GNS2_k127_8652600_5	869210.Marky_1921	1.613e-30	136.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GNS2_k127_8652600_3	483219.LILAB_20340	8.125e-88	303.0	COG0604@1|root,COG0604@2|Bacteria,1MW2V@1224|Proteobacteria,433WU@68525|delta/epsilon subdivisions,2X2BB@28221|Deltaproteobacteria,2YXH4@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_8652600_4	1242864.D187_006616	7.177e-73	272.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X2MT@28221|Deltaproteobacteria,2YTVU@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GNS2_k127_8742405_2	216142.LT40_03515	1.361e-47	181.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
GNS2_k127_8742405_0	861299.J421_3743	1.126e-138	463.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
GNS2_k127_8742405_1	477974.Daud_1110	1.977e-112	376.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GNS2_k127_8747534_0	1121920.AUAU01000004_gene813	5.353e-196	630.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
GNS2_k127_8758963_1	870187.Thini_3809	2.43e-67	239.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,461YN@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GNS2_k127_8758963_0	1121438.JNJA01000007_gene1775	1.473e-70	252.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,42NKX@68525|delta/epsilon subdivisions,2WMAW@28221|Deltaproteobacteria,2M97Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_8758963_2	204669.Acid345_4024	7.442e-35	141.0	COG1309@1|root,COG1309@2|Bacteria,3Y5TS@57723|Acidobacteria,2JK51@204432|Acidobacteriia	204432|Acidobacteriia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GNS2_k127_8767408_2	592015.HMPREF1705_02137	4.056e-75	265.0	COG1879@1|root,COG1879@2|Bacteria,3TASH@508458|Synergistetes	508458|Synergistetes	G	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
GNS2_k127_8767408_3	1120950.KB892768_gene5292	7.906e-50	201.0	296JB@1|root,2ZTUW@2|Bacteria,2IC5D@201174|Actinobacteria,4DU8P@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8767408_1	1382359.JIAL01000001_gene184	1.257e-120	412.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria,2JP2Q@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_8767408_0	1499967.BAYZ01000016_gene6546	4.009e-185	610.0	COG0383@1|root,COG0383@2|Bacteria,2NQ98@2323|unclassified Bacteria	2|Bacteria	G	Alpha mannosidase, middle domain	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	2.3.1.204,3.2.1.170,3.2.1.24	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GNS2_k127_8767408_5	1303518.CCALI_00165	9.834e-36	151.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
GNS2_k127_8767408_4	696369.KI912183_gene2672	4.625e-44	165.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,261S6@186807|Peptococcaceae	186801|Clostridia	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GNS2_k127_8797615_6	1273103.NM10_06292	3.327e-111	370.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4H390@909932|Negativicutes	909932|Negativicutes	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
GNS2_k127_8797615_4	1121430.JMLG01000001_gene2240	5.569e-119	409.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
GNS2_k127_8797615_0	1267535.KB906767_gene1889	0.0	1075.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria,2JMA3@204432|Acidobacteriia	204432|Acidobacteriia	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GNS2_k127_8797615_13	697281.Mahau_0221	1.028e-74	265.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GNS2_k127_8797615_7	404589.Anae109_2088	1.948e-110	390.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GNS2_k127_8797615_14	404589.Anae109_2639	2.376e-72	257.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GNS2_k127_8797615_19	234267.Acid_6217	9.475e-35	148.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
GNS2_k127_8797615_11	502025.Hoch_6519	1.147e-80	293.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria,2Z2YM@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	dmeF	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GNS2_k127_8797615_12	1089553.Tph_c09300	2.884e-75	261.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GNS2_k127_8797615_5	671143.DAMO_1556	2.599e-116	392.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GNS2_k127_8797615_20	521045.Kole_0535	5.61e-24	110.0	COG0802@1|root,COG0802@2|Bacteria,2GDGE@200918|Thermotogae	200918|Thermotogae	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GNS2_k127_8797615_15	1120950.KB892799_gene2147	4.201e-53	205.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GNS2_k127_8797615_10	1307761.L21SP2_1125	1.649e-95	323.0	COG0329@1|root,COG0329@2|Bacteria,2J5J6@203691|Spirochaetes	203691|Spirochaetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GNS2_k127_8797615_9	319225.Plut_0013	1.938e-96	337.0	COG2171@1|root,COG2171@2|Bacteria,1FDRM@1090|Chlorobi	1090|Chlorobi	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
GNS2_k127_8797615_17	1267534.KB906754_gene3732	2.787e-52	189.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8797615_3	234267.Acid_5269	1.647e-165	531.0	COG3391@1|root,COG3391@2|Bacteria,3Y7A2@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
GNS2_k127_8797615_18	1121405.dsmv_3721	4.259e-35	154.0	COG0535@1|root,COG0535@2|Bacteria,1QUN1@1224|Proteobacteria,42WPW@68525|delta/epsilon subdivisions,2WVZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
GNS2_k127_8797615_2	240015.ACP_3315	1.081e-211	668.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,3Y2I9@57723|Acidobacteria,2JHNT@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GNS2_k127_8797615_1	234267.Acid_4491	0.0	1061.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GNS2_k127_8797615_16	215803.DB30_4323	8.483e-53	199.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GNS2_k127_8797615_8	404589.Anae109_3751	5.01e-109	361.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2YTU1@29|Myxococcales	28221|Deltaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GNS2_k127_8824055_4	1120919.AUBI01000005_gene829	0.0005536	46.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,2JR9Z@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GNS2_k127_8824055_3	1121271.AUCM01000008_gene3206	2.805e-12	78.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2UE8E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GNS2_k127_8824055_0	673860.AciM339_0584	1.711e-155	502.0	COG0160@1|root,arCOG00915@2157|Archaea,2XSYT@28890|Euryarchaeota,3F36Y@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.36	ko:K00823,ko:K03918	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00457,R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GNS2_k127_8824055_1	383372.Rcas_2891	8.301e-97	328.0	COG3804@1|root,COG3804@2|Bacteria,2G7MJ@200795|Chloroflexi	200795|Chloroflexi	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
GNS2_k127_8824055_2	1047013.AQSP01000139_gene2383	2.128e-19	103.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516,ko:K05801	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DUF4388,DnaJ,DnaJ_C,TerB,WD40
GNS2_k127_8871271_1	398767.Glov_3415	2e-103	347.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
GNS2_k127_8871271_2	748658.KB907313_gene2336	4.785e-45	187.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GNS2_k127_8871271_0	204669.Acid345_3349	7.012e-143	468.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria,2JHNU@204432|Acidobacteriia	204432|Acidobacteriia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GNS2_k127_8871271_3	1036674.A28LD_1007	7.554e-28	130.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,2QG91@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
GNS2_k127_8871271_4	234267.Acid_0308	3.09e-25	108.0	COG3118@1|root,COG3118@2|Bacteria,3Y53D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GNS2_k127_8871271_6	593117.TGAM_0978	2.025e-05	56.0	COG1672@1|root,arCOG03169@2157|Archaea,2Y162@28890|Euryarchaeota,243JN@183968|Thermococci	183968|Thermococci	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2,HTH_24,Mrr_cat
GNS2_k127_8872268_2	1040983.AXAE01000001_gene2914	6.261e-21	106.0	COG0673@1|root,COG0673@2|Bacteria,1QIQ6@1224|Proteobacteria,2U430@28211|Alphaproteobacteria,43R34@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
GNS2_k127_8872268_1	869210.Marky_0947	1.055e-67	241.0	COG1082@1|root,COG1082@2|Bacteria,1WJN9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GNS2_k127_8872268_0	1267533.KB906736_gene887	3.52e-280	900.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JM3Y@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_8872268_3	502025.Hoch_1436	1.787e-07	63.0	2AA9Q@1|root,30ZJA@2|Bacteria,1QBSA@1224|Proteobacteria,43E6I@68525|delta/epsilon subdivisions,2WZVD@28221|Deltaproteobacteria,2Z2TX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8903808_5	1151061.CAJY01000033_gene1900	5.233e-62	234.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GNS2_k127_8903808_4	1131266.ARWQ01000002_gene677	8.432e-102	339.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
GNS2_k127_8903808_2	247490.KSU1_C0515	2.969e-129	424.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_8903808_3	309807.SRU_0737	4.92e-109	365.0	COG0432@1|root,COG0432@2|Bacteria,4PE9F@976|Bacteroidetes,1FIKK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pfam Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8903808_0	671143.DAMO_1966	0.0	1684.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2NNKQ@2323|unclassified Bacteria	2|Bacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GNS2_k127_8903808_6	448385.sce1473	8.907e-20	106.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
GNS2_k127_8903808_1	861299.J421_3601	1.065e-208	657.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GNS2_k127_8903808_7	1123279.ATUS01000001_gene2440	1.276e-06	57.0	2EN6Y@1|root,33FUT@2|Bacteria,1NHQ0@1224|Proteobacteria,1THBD@1236|Gammaproteobacteria,1JBN4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8907909_10	1382306.JNIM01000001_gene1023	4.446e-23	102.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GNS2_k127_8907909_6	485913.Krac_2433	2.644e-69	239.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GNS2_k127_8907909_12	234267.Acid_4991	3.145e-09	63.0	2CBGA@1|root,32RQS@2|Bacteria,3Y586@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8907909_11	671143.DAMO_0141	3.191e-18	95.0	2EQC7@1|root,33HYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8907909_7	649638.Trad_1754	2.969e-51	189.0	COG4914@1|root,COG4914@2|Bacteria,1WNGG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8907909_0	682795.AciX8_1404	7.044e-290	906.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GNS2_k127_8907909_4	671143.DAMO_1938	9.776e-110	366.0	COG0731@1|root,COG0731@2|Bacteria,2NPIJ@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GNS2_k127_8907909_9	234267.Acid_4208	1.904e-28	124.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
GNS2_k127_8907909_1	945713.IALB_2429	2.025e-145	492.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_8907909_3	204669.Acid345_2603	4.399e-119	402.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria,2JP3M@204432|Acidobacteriia	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GNS2_k127_8907909_2	1121920.AUAU01000012_gene2648	2.57e-127	419.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
GNS2_k127_8907909_5	204669.Acid345_2944	8.377e-79	271.0	COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria,2JKSV@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11
GNS2_k127_8907909_8	204669.Acid345_0767	1.749e-48	185.0	COG0509@1|root,COG0509@2|Bacteria,3Y7RS@57723|Acidobacteria	57723|Acidobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
GNS2_k127_8914462_0	1144275.COCOR_07028	2.934e-223	716.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2WJWZ@28221|Deltaproteobacteria,2YUKJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GNS2_k127_8914462_1	1183438.GKIL_4142	5.089e-56	198.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
GNS2_k127_8914462_2	886293.Sinac_6335	2.101e-52	197.0	COG1490@1|root,COG1490@2|Bacteria,2IZJI@203682|Planctomycetes	203682|Planctomycetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GNS2_k127_8914462_4	1506994.JNLQ01000003_gene3646	7.265e-08	61.0	2DHAX@1|root,32U8Z@2|Bacteria,1UPW0@1239|Firmicutes,25HQ5@186801|Clostridia,4BXPF@830|Butyrivibrio	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8949780_7	1313265.JNIE01000004_gene446	2.113e-22	98.0	COG0511@1|root,COG0511@2|Bacteria,2G46B@200783|Aquificae	200783|Aquificae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GNS2_k127_8949780_1	1306174.JODP01000022_gene46	3.449e-176	563.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria	2|Bacteria	I	Biotin carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GNS2_k127_8949780_5	289376.THEYE_A2006	2.565e-32	133.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3J18S@40117|Nitrospirae	40117|Nitrospirae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8949780_9	1267533.KB906741_gene608	6.564e-16	83.0	2DTIS@1|root,33KJ1@2|Bacteria,3Y5U4@57723|Acidobacteria,2JN6V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8949780_2	1254432.SCE1572_47425	4.098e-126	416.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GNS2_k127_8949780_0	502025.Hoch_0166	1.334e-290	905.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GNS2_k127_8949780_3	713587.THITH_05710	3.927e-106	355.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,1WWNY@135613|Chromatiales	135613|Chromatiales	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
GNS2_k127_8949780_4	243090.RB289	2.664e-60	231.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
GNS2_k127_8949780_6	234267.Acid_1421	7.719e-30	138.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GNS2_k127_8949780_8	756067.MicvaDRAFT_4986	1.3e-17	95.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
GNS2_k127_8950809_9	519989.ECTPHS_01194	0.0001782	52.0	COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1X2ER@135613|Chromatiales	135613|Chromatiales	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.243	ko:K02560	ko00540,ko01100,map00540,map01100	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GNS2_k127_8950809_5	269799.Gmet_2347	2.378e-47	194.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
GNS2_k127_8950809_3	671143.DAMO_1644	2.701e-86	301.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
GNS2_k127_8950809_2	1242864.D187_007162	2.965e-93	317.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
GNS2_k127_8950809_0	401526.TcarDRAFT_0689	2.764e-147	473.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes	909932|Negativicutes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GNS2_k127_8950809_1	264732.Moth_0263	2.366e-137	448.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GNS2_k127_8950809_4	498761.HM1_1604	8.992e-83	298.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GNS2_k127_8950809_8	1121875.KB907548_gene1618	1.884e-09	71.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,AAA_35,Guanylate_cyc,HTH_18,Pkinase,TPR_16,TPR_19,TPR_2,TPR_8
GNS2_k127_8950809_6	886293.Sinac_0810	1.817e-46	183.0	COG0627@1|root,COG0627@2|Bacteria,2J56U@203682|Planctomycetes	203682|Planctomycetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GNS2_k127_8950809_7	926566.Terro_1919	2.091e-18	98.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria,2JJVA@204432|Acidobacteriia	204432|Acidobacteriia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GNS2_k127_8962628_7	204669.Acid345_2431	3.25e-25	109.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GNS2_k127_8962628_3	234267.Acid_3676	9.638e-68	235.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GNS2_k127_8962628_4	945713.IALB_0838	6.915e-67	235.0	COG1435@1|root,COG1435@2|Bacteria	2|Bacteria	F	thymidine kinase activity	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
GNS2_k127_8962628_12	1089552.KI911559_gene813	0.0002362	49.0	2CCG0@1|root,2ZVGB@2|Bacteria,1P9KG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8962628_1	1255043.TVNIR_1256	8.461e-84	290.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
GNS2_k127_8962628_9	404589.Anae109_0188	1.46e-07	64.0	2ETNZ@1|root,33M6P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8962628_2	234267.Acid_7921	3.073e-71	258.0	COG1136@1|root,COG1136@2|Bacteria,3Y2QD@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_8962628_10	1415780.JPOG01000001_gene1721	1.918e-07	61.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1X5BW@135614|Xanthomonadales	135614|Xanthomonadales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GNS2_k127_8962628_5	525904.Tter_1099	4.034e-52	206.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_8962628_8	204669.Acid345_1884	5.467e-16	83.0	COG4818@1|root,COG4818@2|Bacteria,3Y5MZ@57723|Acidobacteria,2JK19@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,zinc_ribbon_2
GNS2_k127_8962628_11	51337.XP_004670602.1	6.782e-05	55.0	COG0457@1|root,KOG2003@2759|Eukaryota,38B6J@33154|Opisthokonta,3BB9Q@33208|Metazoa,3CR5Z@33213|Bilateria,480R4@7711|Chordata,496CC@7742|Vertebrata,3JDWC@40674|Mammalia,35GG1@314146|Euarchontoglires,4PWY1@9989|Rodentia	33208|Metazoa	S	Anaphase-promoting complex, cyclosome, subunit 3	IFT88	GO:0000003,GO:0000226,GO:0000902,GO:0000904,GO:0001578,GO:0001654,GO:0001655,GO:0001669,GO:0001822,GO:0001885,GO:0001886,GO:0001889,GO:0001944,GO:0002064,GO:0002080,GO:0002081,GO:0002119,GO:0002164,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003158,GO:0003205,GO:0003206,GO:0003279,GO:0003382,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005813,GO:0005814,GO:0005815,GO:0005856,GO:0005929,GO:0005930,GO:0006810,GO:0006928,GO:0006950,GO:0006970,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007018,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007224,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007288,GO:0007289,GO:0007290,GO:0007368,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007507,GO:0007600,GO:0007605,GO:0007610,GO:0007626,GO:0008092,GO:0008104,GO:0008150,GO:0008283,GO:0008285,GO:0008544,GO:0008589,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009894,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010506,GO:0010646,GO:0010647,GO:0010970,GO:0012505,GO:0012506,GO:0014706,GO:0015630,GO:0016020,GO:0016043,GO:0016241,GO:0019222,GO:0019894,GO:0019953,GO:0021510,GO:0021511,GO:0021513,GO:0021537,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022611,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030031,GO:0030141,GO:0030154,GO:0030162,GO:0030182,GO:0030317,GO:0030323,GO:0030324,GO:0030326,GO:0030659,GO:0030667,GO:0030705,GO:0030855,GO:0030900,GO:0030990,GO:0030992,GO:0031016,GO:0031090,GO:0031122,GO:0031175,GO:0031323,GO:0031329,GO:0031344,GO:0031410,GO:0031503,GO:0031514,GO:0031982,GO:0031984,GO:0032101,GO:0032103,GO:0032391,GO:0032421,GO:0032501,GO:0032502,GO:0032504,GO:0032838,GO:0032989,GO:0032991,GO:0033036,GO:0033043,GO:0034405,GO:0035051,GO:0035082,GO:0035107,GO:0035108,GO:0035113,GO:0035295,GO:0035640,GO:0035641,GO:0035735,GO:0035869,GO:0036064,GO:0036334,GO:0040011,GO:0040012,GO:0040017,GO:0040024,GO:0042073,GO:0042127,GO:0042481,GO:0042487,GO:0042490,GO:0042592,GO:0042692,GO:0042733,GO:0042995,GO:0043005,GO:0043053,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043567,GO:0043568,GO:0043583,GO:0044085,GO:0044087,GO:0044088,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044431,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044447,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045446,GO:0045595,GO:0045598,GO:0046907,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048645,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048732,GO:0048736,GO:0048738,GO:0048839,GO:0048853,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048872,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050877,GO:0050896,GO:0050920,GO:0050921,GO:0050954,GO:0051128,GO:0051146,GO:0051171,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0055007,GO:0055115,GO:0060021,GO:0060091,GO:0060113,GO:0060119,GO:0060122,GO:0060173,GO:0060255,GO:0060259,GO:0060271,GO:0060322,GO:0060411,GO:0060426,GO:0060429,GO:0060491,GO:0060537,GO:0060541,GO:0060914,GO:0061008,GO:0061061,GO:0061351,GO:0065007,GO:0065008,GO:0070613,GO:0070925,GO:0071840,GO:0072001,GO:0072358,GO:0072359,GO:0080090,GO:0090102,GO:0097014,GO:0097223,GO:0097435,GO:0097458,GO:0097541,GO:0097542,GO:0097546,GO:0097708,GO:0097722,GO:0097730,GO:0097731,GO:0097732,GO:0097733,GO:0098588,GO:0098589,GO:0098791,GO:0098805,GO:0098862,GO:0099111,GO:0099503,GO:0099568,GO:0120025,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0120038,GO:1902017,GO:1902115,GO:1903317,GO:1903929,GO:1905515,GO:2000026,GO:2000027,GO:2000785	-	ko:K16474	-	-	-	-	ko00000,ko03036	-	-	-	TPR_1,TPR_12,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
GNS2_k127_8962628_6	671143.DAMO_0450	2.838e-39	158.0	COG0741@1|root,COG0741@2|Bacteria,2NPR5@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
GNS2_k127_8962628_0	1242864.D187_003508	1.051e-251	805.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GNS2_k127_8985804_0	1125863.JAFN01000001_gene389	2.74e-110	370.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GNS2_k127_8985804_1	1125863.JAFN01000001_gene3091	1.447e-107	357.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GNS2_k127_8987641_1	1267533.KB906740_gene318	3.291e-29	134.0	COG0265@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
GNS2_k127_8987641_3	887062.HGR_04828	0.0002133	52.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,2WERU@28216|Betaproteobacteria,4AF1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GNS2_k127_8987641_0	1396418.BATQ01000054_gene30	3.144e-97	345.0	COG2898@1|root,COG2898@2|Bacteria,46ZGD@74201|Verrucomicrobia,2IUPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterised conserved protein (DUF2156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2156,VirJ
GNS2_k127_8987641_2	1304885.AUEY01000017_gene3764	2.655e-22	113.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,43AE6@68525|delta/epsilon subdivisions,2X6A8@28221|Deltaproteobacteria,2MPXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GNS2_k127_8987641_4	1173028.ANKO01000197_gene6047	0.000838	46.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS,NACHT
GNS2_k127_8994451_1	523794.Lebu_2162	8.091e-54	200.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GNS2_k127_8994451_0	658088.HMPREF0987_01570	2.202e-70	254.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,27J3V@186928|unclassified Lachnospiraceae	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_8994451_2	1356852.N008_19045	2.234e-22	108.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,47PB0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GNS2_k127_9010350_0	1254432.SCE1572_30715	2.635e-43	170.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GNS2_k127_9010350_3	335543.Sfum_3248	4.458e-09	61.0	2EQZT@1|root,33IJD@2|Bacteria,1NKTX@1224|Proteobacteria,42XNG@68525|delta/epsilon subdivisions,2WTCK@28221|Deltaproteobacteria,2MQPM@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9010350_2	502025.Hoch_6592	2.37e-24	116.0	2AI7D@1|root,318MR@2|Bacteria,1Q0MU@1224|Proteobacteria,436RD@68525|delta/epsilon subdivisions,2X1E8@28221|Deltaproteobacteria,2YW7E@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9010350_1	290397.Adeh_3592	5.663e-39	153.0	2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,43BG3@68525|delta/epsilon subdivisions,2X6UE@28221|Deltaproteobacteria,2Z3CV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9010350_4	1121448.DGI_2478	3.131e-05	54.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GNS2_k127_9061720_9	215803.DB30_5467	1.611e-15	89.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GNS2_k127_9061720_0	1382359.JIAL01000001_gene2955	5.139e-131	435.0	COG0180@1|root,COG0180@2|Bacteria,3Y2VN@57723|Acidobacteria,2JHXI@204432|Acidobacteriia	204432|Acidobacteriia	J	aminoacyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GNS2_k127_9061720_5	1047013.AQSP01000083_gene1194	7.906e-47	179.0	COG1994@1|root,COG1994@2|Bacteria,2NPQP@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	ywhC	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
GNS2_k127_9061720_1	517418.Ctha_0840	1.084e-77	277.0	COG0477@1|root,COG2814@2|Bacteria,1FDXJ@1090|Chlorobi	1090|Chlorobi	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GNS2_k127_9061720_3	647113.Metok_1036	9.253e-62	233.0	COG0642@1|root,arCOG02322@1|root,arCOG02322@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,23RVT@183939|Methanococci	183939|Methanococci	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
GNS2_k127_9061720_8	351160.RCIX443	6.632e-27	126.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GNS2_k127_9061720_4	1157490.EL26_16960	1.997e-54	208.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,2785U@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GNS2_k127_9061720_2	96561.Dole_1514	5.873e-73	265.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria,2MM49@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
GNS2_k127_9061720_10	188626.HMPREF0321_0282	1.57e-07	65.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,1ZVZ9@145357|Dermacoccaceae	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
GNS2_k127_9061720_11	1121930.AQXG01000012_gene3205	0.0001735	54.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
GNS2_k127_9068152_0	1047013.AQSP01000114_gene692	1.575e-49	178.0	COG0384@1|root,COG0384@2|Bacteria,2NR2U@2323|unclassified Bacteria	2|Bacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GNS2_k127_9068152_5	215803.DB30_3579	8.988e-11	73.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
GNS2_k127_9068152_1	204669.Acid345_0553	2.351e-39	155.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
GNS2_k127_9068152_3	234267.Acid_4299	3.305e-27	115.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria	57723|Acidobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GNS2_k127_9068152_2	526226.Gbro_4653	8.725e-38	151.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4GBAY@85026|Gordoniaceae	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
GNS2_k127_9068152_4	326427.Cagg_2798	3.675e-20	101.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GNS2_k127_909594_3	1333523.L593_04875	1.459e-08	62.0	COG4745@1|root,arCOG00562@2157|Archaea,2XW4A@28890|Euryarchaeota,23UFU@183963|Halobacteria	183963|Halobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_909594_0	1267533.KB906741_gene446	6.761e-277	869.0	COG1297@1|root,COG1297@2|Bacteria,3Y2UT@57723|Acidobacteria,2JHIU@204432|Acidobacteriia	204432|Acidobacteriia	S	Oligopeptide transporter OPT	-	-	-	-	-	-	-	-	-	-	-	-	OPT
GNS2_k127_909594_2	1121920.AUAU01000005_gene1098	5.532e-63	226.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
GNS2_k127_909594_1	1382359.JIAL01000001_gene170	1.222e-181	609.0	COG1629@1|root,COG1629@2|Bacteria,3Y2K8@57723|Acidobacteria,2JKEC@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
GNS2_k127_9096596_1	204669.Acid345_4495	6.717e-106	361.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria,2JIBN@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
GNS2_k127_9096596_2	1122137.AQXF01000001_gene2948	1.016e-36	147.0	COG3382@1|root,COG3382@2|Bacteria,1N6A7@1224|Proteobacteria,2UJ4A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
GNS2_k127_9096596_0	671143.DAMO_2896	9.873e-206	664.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GNS2_k127_9101041_0	1120973.AQXL01000135_gene1467	2.046e-266	828.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,2782U@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GNS2_k127_9106342_1	338966.Ppro_0383	7.157e-82	284.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
GNS2_k127_9106342_0	240015.ACP_1472	4.347e-191	622.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GNS2_k127_9114635_4	164757.Mjls_5595	1.335e-10	64.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,23416@1762|Mycobacteriaceae	201174|Actinobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GNS2_k127_9114635_1	251221.35213545	8.176e-31	133.0	COG0739@1|root,COG0739@2|Bacteria,1G076@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GNS2_k127_9114635_2	671143.DAMO_2902	7.349e-26	120.0	2CKY4@1|root,328RE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9114635_3	608538.HTH_1756	2.499e-25	113.0	COG4659@1|root,COG4659@2|Bacteria,2G4YT@200783|Aquificae	200783|Aquificae	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
GNS2_k127_9114635_0	1116472.MGMO_152c00120	2.442e-98	337.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9114635_6	338966.Ppro_0994	0.0005039	53.0	COG3167@1|root,COG3167@2|Bacteria,1MZZ4@1224|Proteobacteria,43B6P@68525|delta/epsilon subdivisions,2X6K9@28221|Deltaproteobacteria,43TSB@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
GNS2_k127_9120917_10	1047013.AQSP01000144_gene860	1.753e-13	80.0	COG2244@1|root,COG2244@2|Bacteria,2NPWA@2323|unclassified Bacteria	2|Bacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GNS2_k127_9120917_12	562970.Btus_3142	7.525e-08	66.0	COG1807@1|root,COG1807@2|Bacteria,1UYTF@1239|Firmicutes,4HE47@91061|Bacilli,278F8@186823|Alicyclobacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_9120917_1	562970.Btus_1805	2.718e-133	458.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
GNS2_k127_9120917_3	1340493.JNIF01000003_gene2455	5.863e-105	355.0	COG0075@1|root,COG0075@2|Bacteria,3Y3I6@57723|Acidobacteria	57723|Acidobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GNS2_k127_9120917_2	1173025.GEI7407_3431	1.043e-119	396.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria,1H98I@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GNS2_k127_9120917_8	643473.KB235930_gene2840	2.323e-39	152.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIYG@1161|Nostocales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,Response_reg
GNS2_k127_9120917_11	204669.Acid345_3996	5.561e-13	73.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9120917_4	868595.Desca_1276	4.555e-93	327.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
GNS2_k127_9120917_6	880072.Desac_2926	1.222e-53	194.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MQHK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GNS2_k127_9120917_7	760568.Desku_1253	2.034e-39	155.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,262G6@186807|Peptococcaceae	186801|Clostridia	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
GNS2_k127_9120917_0	204669.Acid345_4392	3.787e-147	488.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GNS2_k127_9120917_5	204669.Acid345_4392	7.358e-64	244.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GNS2_k127_9120917_9	1267533.KB906733_gene2955	1.509e-27	115.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria,2JHRS@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GNS2_k127_9124736_7	1430331.EP10_17830	0.0004311	51.0	COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,1WE6C@129337|Geobacillus	91061|Bacilli	K	Putative zinc-finger	rsiW	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
GNS2_k127_9124736_6	383372.Rcas_0731	1.797e-28	123.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GNS2_k127_9124736_0	1278073.MYSTI_05376	1.1e-166	541.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,43C8U@68525|delta/epsilon subdivisions,2X7J6@28221|Deltaproteobacteria,2Z3H1@29|Myxococcales	28221|Deltaproteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
GNS2_k127_9124736_1	1403819.BATR01000020_gene706	2.622e-128	428.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase
GNS2_k127_9124736_4	404589.Anae109_2092	3.777e-72	256.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
GNS2_k127_9124736_2	370438.PTH_1130	1.087e-119	396.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GNS2_k127_9124736_5	639282.DEFDS_0269	1.388e-51	188.0	COG0242@1|root,COG0242@2|Bacteria,2GFNS@200930|Deferribacteres	200930|Deferribacteres	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GNS2_k127_9124736_3	443144.GM21_0649	2.986e-87	305.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GNS2_k127_9136922_2	1485544.JQKP01000002_gene1376	8.02e-19	103.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,44V4V@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
GNS2_k127_9136922_4	82654.Pse7367_0893	3.005e-10	72.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
GNS2_k127_9136922_0	204669.Acid345_1588	1.913e-140	462.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GNS2_k127_9136922_1	383372.Rcas_0453	3.003e-86	318.0	COG0421@1|root,COG0421@2|Bacteria,2G80S@200795|Chloroflexi,37634@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9136922_3	714083.JH370377_gene2647	1.475e-13	86.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4FTMS@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl transferases group 1	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GNS2_k127_9137406_0	251229.Chro_4009	1.077e-121	426.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
GNS2_k127_9137406_2	266117.Rxyl_2621	1.745e-31	132.0	COG1656@1|root,COG1656@2|Bacteria	2|Bacteria	F	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
GNS2_k127_9137406_1	1430440.MGMSRv2_3724	1.36e-76	275.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JSNQ@204441|Rhodospirillales	204441|Rhodospirillales	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
GNS2_k127_9175168_5	641491.DND132_0207	5.618e-25	108.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GNS2_k127_9175168_3	641491.DND132_0206	2.593e-46	182.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	rfbD	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GNS2_k127_9175168_1	641491.DND132_0205	3.511e-64	235.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MA46@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	pfam abc	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GNS2_k127_9175168_4	479434.Sthe_0904	1.65e-42	171.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GNS2_k127_9175168_2	323261.Noc_0748	5.777e-64	247.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GNS2_k127_9175168_0	926566.Terro_1412	4.666e-85	290.0	COG1732@1|root,COG1732@2|Bacteria,3Y3Z9@57723|Acidobacteria,2JIDY@204432|Acidobacteriia	204432|Acidobacteriia	M	ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
GNS2_k127_917998_6	1047013.AQSP01000077_gene2268	2.243e-36	140.0	COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
GNS2_k127_917998_0	497964.CfE428DRAFT_4291	8.438e-138	474.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GNS2_k127_917998_3	448385.sce0169	7.063e-77	273.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,43413@68525|delta/epsilon subdivisions,2X4K3@28221|Deltaproteobacteria,2YZ68@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
GNS2_k127_917998_4	1158338.JNLJ01000001_gene872	2.614e-62	235.0	COG0568@1|root,COG0568@2|Bacteria,2G3PM@200783|Aquificae	200783|Aquificae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GNS2_k127_917998_5	639030.JHVA01000001_gene1750	2.401e-53	206.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GNS2_k127_917998_2	864563.HMPREF9166_1392	3.794e-81	294.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4H21Y@909932|Negativicutes	909932|Negativicutes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GNS2_k127_917998_1	1071679.BG57_10360	3.862e-114	404.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
GNS2_k127_917998_7	234267.Acid_1298	0.0002252	51.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
GNS2_k127_9206805_5	489825.LYNGBM3L_59110	2.524e-12	81.0	COG1388@1|root,COG3291@1|root,COG1388@2|Bacteria,COG3291@2|Bacteria,1GI88@1117|Cyanobacteria,1HEP0@1150|Oscillatoriales	1117|Cyanobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9206805_4	316274.Haur_0489	2.044e-65	254.0	COG3591@1|root,COG4412@1|root,COG3591@2|Bacteria,COG4412@2|Bacteria,2GB3W@200795|Chloroflexi,377V9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM von Willebrand factor type A	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	VWA
GNS2_k127_9206805_1	1122182.KB903825_gene491	1.69e-143	492.0	COG4935@1|root,COG5276@1|root,COG4935@2|Bacteria,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria,4DBJS@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
GNS2_k127_9206805_2	383372.Rcas_3570	7.401e-142	479.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
GNS2_k127_9206805_3	595494.Tola_1754	1.055e-74	259.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1Y61V@135624|Aeromonadales	135624|Aeromonadales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GNS2_k127_9206805_0	748280.NH8B_3871	7.551e-172	558.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,2KPRT@206351|Neisseriales	206351|Neisseriales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GNS2_k127_9219080_8	1267005.KB911259_gene3875	4.398e-06	58.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,3N6E0@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GNS2_k127_9219080_4	1382306.JNIM01000001_gene1598	1.824e-64	229.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_9219080_3	1385511.N783_19800	4.251e-74	254.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2Y8N8@289201|Pontibacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GNS2_k127_9219080_1	316274.Haur_1203	1.912e-118	387.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
GNS2_k127_9219080_2	240015.ACP_2330	1.654e-84	307.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
GNS2_k127_9219080_7	1121439.dsat_0456	5.515e-33	134.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MB4E@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
GNS2_k127_9219080_6	1254432.SCE1572_42360	7.47e-34	134.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2YVKR@29|Myxococcales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GNS2_k127_9219080_0	246194.CHY_2365	5.371e-164	537.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
GNS2_k127_9236374_2	1499967.BAYZ01000066_gene6078	4.586e-61	230.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
GNS2_k127_9236374_1	1210884.HG799465_gene12055	1.038e-67	257.0	COG2308@1|root,COG2308@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	CP_ATPgrasp_2,GSP_synth
GNS2_k127_9236374_0	671143.DAMO_2139	5.325e-113	373.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GNS2_k127_9236914_2	861299.J421_0692	2.111e-54	193.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GNS2_k127_9236914_3	402881.Plav_3503	3.536e-39	151.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,1JP80@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GNS2_k127_9236914_1	1499967.BAYZ01000049_gene2751	5.641e-130	436.0	COG0001@1|root,COG0001@2|Bacteria	2|Bacteria	H	glutamate-1-semialdehyde 2,1-aminomutase activity	hemL	-	5.4.3.8	ko:K01845,ko:K07257	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3,CTP_transf_3
GNS2_k127_9236914_0	1499967.BAYZ01000049_gene2751	2.564e-136	456.0	COG0001@1|root,COG0001@2|Bacteria	2|Bacteria	H	glutamate-1-semialdehyde 2,1-aminomutase activity	hemL	-	5.4.3.8	ko:K01845,ko:K07257	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3,CTP_transf_3
GNS2_k127_9236914_4	1121438.JNJA01000011_gene1808	9.705e-16	89.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,2MAGK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GNS2_k127_9236914_5	1306174.JODP01000006_gene2917	3.052e-13	73.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
GNS2_k127_9249202_1	502025.Hoch_0177	1.052e-36	145.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMJ8@28221|Deltaproteobacteria,2Z2Y9@29|Myxococcales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GNS2_k127_9249202_2	867903.ThesuDRAFT_00795	1.127e-30	136.0	COG0328@1|root,COG2384@1|root,COG0328@2|Bacteria,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3WDGE@538999|Clostridiales incertae sedis	186801|Clostridia	L	tRNA (adenine(22)-N(1))-methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
GNS2_k127_9249202_4	530564.Psta_0355	1.138e-16	85.0	2DMHE@1|root,32RJ5@2|Bacteria,2J0F1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9249202_0	344747.PM8797T_14189	6.715e-116	387.0	COG3220@1|root,COG3220@2|Bacteria,2IY8B@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
GNS2_k127_9249202_3	448385.sce3434	6.731e-24	112.0	COG3219@1|root,COG3219@2|Bacteria,1RI5N@1224|Proteobacteria,435AA@68525|delta/epsilon subdivisions,2WZMC@28221|Deltaproteobacteria,2Z2DA@29|Myxococcales	28221|Deltaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
GNS2_k127_9271902_0	1502852.FG94_03239	5.328e-48	180.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VRVE@28216|Betaproteobacteria,475TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_9271902_2	1379698.RBG1_1C00001G0683	2.367e-28	117.0	COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria	2|Bacteria	P	(Rieske (2Fe-2S) domain)	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GNS2_k127_9271902_1	383372.Rcas_0995	6.26e-42	176.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi,376D4@32061|Chloroflexia	32061|Chloroflexia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_8
GNS2_k127_9277966_1	1267535.KB906767_gene1391	6.462e-21	105.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GNS2_k127_9277966_0	266117.Rxyl_2838	1.617e-142	464.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4CPPR@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GNS2_k127_9282149_1	1379698.RBG1_1C00001G0471	1.275e-196	618.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GNS2_k127_9282149_2	1094466.KQS_08725	7.194e-125	411.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,2NSZG@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GNS2_k127_9282149_4	1282360.ABAC460_19855	6.228e-93	319.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,PPC,Peptidase_M10_C
GNS2_k127_9282149_5	1232410.KI421424_gene1720	8.962e-80	285.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43S42@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	HrcA protein C terminal domain	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
GNS2_k127_9282149_6	1211114.ALIP01000140_gene2329	2.986e-29	134.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1X6HN@135614|Xanthomonadales	135614|Xanthomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GNS2_k127_9282149_0	1123376.AUIU01000011_gene862	2.141e-226	717.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GNS2_k127_9282149_3	1123392.AQWL01000007_gene926	2.962e-119	393.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KRI6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GNS2_k127_9282149_7	1121920.AUAU01000019_gene2592	1.182e-06	55.0	COG2264@1|root,COG2264@2|Bacteria,3Y5SG@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GNS2_k127_9291253_4	448385.sce6683	6.7e-07	61.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2WKH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GNS2_k127_9291253_0	671143.DAMO_3136	0.0	1068.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
GNS2_k127_9291253_3	1232410.KI421420_gene3159	4.12e-34	150.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GNS2_k127_9291253_2	204669.Acid345_2869	1.073e-66	246.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria,2JJTI@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GNS2_k127_9291253_1	1144275.COCOR_03218	8.042e-70	248.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUWE@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD3	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GNS2_k127_9319647_0	204669.Acid345_2868	6.986e-148	479.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria,2JI17@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GNS2_k127_9355221_0	575540.Isop_3575	1.4e-167	559.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
GNS2_k127_9355221_6	903818.KI912268_gene1040	3.979e-53	201.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
GNS2_k127_9355221_5	330214.NIDE2766	2.139e-63	222.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
GNS2_k127_9355221_4	1293047.CBMA010000012_gene778	1.837e-63	231.0	COG0524@1|root,arCOG00014@2157|Archaea,2XTPM@28890|Euryarchaeota,23SEY@183963|Halobacteria	183963|Halobacteria	G	COG0524 Sugar kinases, ribokinase family	pfk1	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
GNS2_k127_9355221_2	1121430.JMLG01000017_gene284	5.703e-101	357.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,260V0@186807|Peptococcaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GNS2_k127_9355221_1	338966.Ppro_2321	3.283e-138	460.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,43TWH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GNS2_k127_9355221_7	1267533.KB906734_gene4347	1.466e-50	193.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GNS2_k127_9355221_8	1379270.AUXF01000004_gene3248	6.215e-37	155.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GNS2_k127_9355221_3	278963.ATWD01000002_gene938	6.018e-94	316.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GNS2_k127_9355221_9	411467.BACCAP_04464	2.215e-20	93.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9364823_2	682795.AciX8_0906	7.018e-06	51.0	COG0500@1|root,COG2226@2|Bacteria,3Y58M@57723|Acidobacteria,2JJRE@204432|Acidobacteriia	204432|Acidobacteriia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GNS2_k127_9364823_1	404589.Anae109_3445	4.59e-08	65.0	COG3637@1|root,COG3637@2|Bacteria,1Q8YQ@1224|Proteobacteria,42YH1@68525|delta/epsilon subdivisions,2WTT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9364823_0	661478.OP10G_1347	1.947e-88	303.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GNS2_k127_9434546_0	479434.Sthe_0805	1.478e-148	500.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,27Y57@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
GNS2_k127_9434546_1	1396141.BATP01000059_gene2564	5.383e-145	472.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
GNS2_k127_9434546_4	1239962.C943_02138	6.458e-35	150.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
GNS2_k127_9434546_3	1239962.C943_02139	2.655e-88	308.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GNS2_k127_9434546_2	1047013.AQSP01000131_gene1840	4.795e-104	359.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
GNS2_k127_9442068_3	290397.Adeh_0139	4.483e-63	228.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
GNS2_k127_9442068_2	1047013.AQSP01000052_gene2599	3.646e-75	280.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GNS2_k127_9442068_1	1047013.AQSP01000052_gene2600	5.508e-97	325.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GNS2_k127_9442068_4	1385515.N791_03775	1.632e-37	160.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X6MM@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
GNS2_k127_9442068_8	994573.T472_0212685	6.653e-05	54.0	COG3807@1|root,COG4990@1|root,COG3807@2|Bacteria,COG4990@2|Bacteria,1V2NM@1239|Firmicutes	1239|Firmicutes	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Peptidase_C39_2,SH3_3
GNS2_k127_9442068_0	204669.Acid345_3445	4.309e-103	342.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria,2JIDE@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GNS2_k127_9442068_7	204669.Acid345_0805	2.363e-10	68.0	COG1225@1|root,COG1225@2|Bacteria,3Y8N3@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GNS2_k127_9442068_5	1267535.KB906767_gene3216	2.056e-15	87.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
GNS2_k127_9442068_6	525904.Tter_0752	7.114e-13	70.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
GNS2_k127_9481815_3	204669.Acid345_3000	2.318e-60	226.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GNS2_k127_9481815_2	1128421.JAGA01000003_gene2872	6.097e-65	246.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GNS2_k127_9481815_1	1128421.JAGA01000003_gene2871	2.879e-211	689.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
GNS2_k127_9481815_0	472759.Nhal_2603	8.879e-257	808.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
GNS2_k127_9535084_2	290397.Adeh_4335	4.772e-06	53.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
GNS2_k127_9535084_1	338963.Pcar_0090	8.261e-21	102.0	COG0760@1|root,COG0760@2|Bacteria,1RKBZ@1224|Proteobacteria,42SAP@68525|delta/epsilon subdivisions,2WPWG@28221|Deltaproteobacteria,43SKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
GNS2_k127_9535084_0	1267535.KB906767_gene1342	3.868e-272	868.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GNS2_k127_9545830_1	1499967.BAYZ01000158_gene441	2.76e-22	106.0	COG2834@1|root,COG2834@2|Bacteria,2NQ6V@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
GNS2_k127_9545830_0	1047013.AQSP01000036_gene1385	4.381e-98	343.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
GNS2_k127_9545830_2	1165096.ARWF01000001_gene2066	8.78e-08	56.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VV31@28216|Betaproteobacteria,2KN8M@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GNS2_k127_9546369_2	997346.HMPREF9374_1821	3.547e-18	99.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,4IRFV@91061|Bacilli,27BU9@186824|Thermoactinomycetaceae	91061|Bacilli	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
GNS2_k127_9546369_3	1198114.AciX9_3014	5.693e-08	67.0	2E63T@1|root,330SU@2|Bacteria,3Y5AZ@57723|Acidobacteria,2JJSJ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9546369_0	1047013.AQSP01000085_gene1982	7.722e-26	113.0	COG1430@1|root,COG1430@2|Bacteria,2NQ88@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GNS2_k127_9546369_1	1047013.AQSP01000099_gene1495	2.646e-20	93.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GNS2_k127_9551259_0	1242864.D187_005812	1.378e-117	396.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GNS2_k127_9567386_0	404589.Anae109_3834	7.772e-77	267.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
GNS2_k127_9567386_2	1047013.AQSP01000079_gene2043	1.669e-47	180.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
GNS2_k127_9567386_1	234267.Acid_1281	5.994e-61	217.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
GNS2_k127_9575585_1	1121920.AUAU01000004_gene627	2.757e-61	231.0	COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
GNS2_k127_9575585_0	290397.Adeh_2972	4.865e-91	311.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
GNS2_k127_960990_0	1192034.CAP_8277	3.799e-73	281.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
GNS2_k127_960990_2	234267.Acid_1797	1.125e-51	188.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
GNS2_k127_960990_1	861299.J421_4062	3.481e-60	235.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GNS2_k127_961829_2	63737.Npun_F3174	7.318e-13	80.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
GNS2_k127_961829_1	709986.Deima_1843	8.611e-15	83.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
GNS2_k127_961829_0	1150864.MILUP08_40651	1.039e-40	157.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DAUI@85008|Micromonosporales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	Arth_4141	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
GNS2_k127_9650339_1	1382356.JQMP01000001_gene1008	1.324e-16	91.0	29X1J@1|root,30IPW@2|Bacteria,2GBCF@200795|Chloroflexi,27YRV@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9650339_0	945713.IALB_2036	5.99e-184	586.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfp	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135	2.7.1.11,2.7.1.90	ko:K00850,ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GNS2_k127_9654958_0	1382359.JIAL01000001_gene2922	0.0	1022.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GNS2_k127_9661677_0	926566.Terro_1866	1.515e-108	368.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria,2JKD7@204432|Acidobacteriia	204432|Acidobacteriia	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_9661677_1	1382356.JQMP01000001_gene1011	2.852e-72	259.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	189775|Thermomicrobia	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GNS2_k127_9661677_2	1303518.CCALI_01733	9.268e-42	159.0	COG0780@1|root,COG0780@2|Bacteria	2|Bacteria	G	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GNS2_k127_9668420_0	1379270.AUXF01000003_gene3738	3.539e-127	428.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_9668420_3	1185876.BN8_05036	3.862e-85	292.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GNS2_k127_9668420_4	518766.Rmar_0540	2.818e-64	234.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1FJCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
GNS2_k127_9668420_5	404589.Anae109_2403	9.1e-38	163.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42N26@68525|delta/epsilon subdivisions,2WK9Q@28221|Deltaproteobacteria,2Z34B@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
GNS2_k127_9668420_1	404589.Anae109_2774	3.601e-120	397.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GNS2_k127_9668420_6	756067.MicvaDRAFT_0156	3.464e-17	96.0	COG1404@1|root,COG2931@1|root,COG4257@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4257@2|Bacteria,1G7BP@1117|Cyanobacteria,1HCF5@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
GNS2_k127_9668420_2	1121920.AUAU01000005_gene1090	1.262e-89	300.0	COG2884@1|root,COG2884@2|Bacteria	2|Bacteria	D	Cell division ATP-binding protein ftsE	ftsE	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
GNS2_k127_9678265_0	706587.Desti_3189	4.463e-136	448.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA-4	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
GNS2_k127_9678265_1	1396418.BATQ01000175_gene2786	1.692e-121	398.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,SDH_sah
GNS2_k127_9681804_3	1391647.AVSV01000017_gene670	4.561e-32	133.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,36EYH@31979|Clostridiaceae	186801|Clostridia	S	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
GNS2_k127_9681804_7	649638.Trad_1397	3.595e-06	56.0	2EFYU@1|root,339R0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
GNS2_k127_9681804_5	1075090.GOAMR_76_00560	1.301e-27	120.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4GGRX@85026|Gordoniaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
GNS2_k127_9681804_1	1121920.AUAU01000004_gene645	4.089e-117	411.0	COG0479@1|root,COG0479@2|Bacteria,3Y3XR@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
GNS2_k127_9681804_0	234267.Acid_7402	0.0	1061.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GNS2_k127_9681804_2	1267535.KB906767_gene403	4.429e-57	223.0	COG2009@1|root,COG2009@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241,ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iYO844.BSU28450	Sdh_cyt
GNS2_k127_9681804_6	1173028.ANKO01000096_gene2785	1.34e-20	106.0	COG2197@1|root,COG2197@2|Bacteria,1G0N8@1117|Cyanobacteria,1H7M9@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GNS2_k127_9681804_4	1177181.T9A_00609	2.801e-31	134.0	COG1075@1|root,COG1075@2|Bacteria,1NGMF@1224|Proteobacteria	1224|Proteobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
GNS2_k127_9687289_2	479434.Sthe_1803	9.98e-43	165.0	COG1587@1|root,COG1587@2|Bacteria,2GBWA@200795|Chloroflexi,27Z62@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
GNS2_k127_9687289_0	335543.Sfum_2118	5.64e-209	666.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MR1P@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GNS2_k127_9687289_4	1267535.KB906767_gene253	8.777e-30	125.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GNS2_k127_9687289_5	1110502.TMO_0200	1.481e-16	94.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2JQU2@204441|Rhodospirillales	204441|Rhodospirillales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
GNS2_k127_9687289_3	234267.Acid_4300	7.185e-42	177.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
GNS2_k127_9687289_6	118168.MC7420_690	1.925e-12	80.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria,1H6WW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
GNS2_k127_9687289_1	997346.HMPREF9374_0975	8.905e-61	233.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,27AWZ@186824|Thermoactinomycetaceae	91061|Bacilli	E	Diaminopimelate epimerase	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GNS2_k127_9714292_1	246197.MXAN_2901	1.579e-48	192.0	COG0602@1|root,COG0602@2|Bacteria,1RA7S@1224|Proteobacteria,42SBH@68525|delta/epsilon subdivisions,2WRYF@28221|Deltaproteobacteria,2Z172@29|Myxococcales	28221|Deltaproteobacteria	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	-	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GNS2_k127_9714292_0	290397.Adeh_0291	1.645e-225	709.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
GNS2_k127_9717275_1	671143.DAMO_3041	1.734e-05	49.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
GNS2_k127_9717275_0	1121920.AUAU01000004_gene908	5.46e-79	278.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
GNS2_k127_9754435_2	926550.CLDAP_09380	7.211e-09	60.0	2ATK2@1|root,31J48@2|Bacteria,2G9PZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GNS2_k127_9754435_0	485913.Krac_11202	1.77e-158	513.0	COG3670@1|root,COG3670@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
GNS2_k127_9754435_1	1254432.SCE1572_06430	1.646e-44	166.0	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GNS2_k127_9773923_1	448385.sce6976	5.212e-130	441.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
GNS2_k127_9773923_0	886293.Sinac_1156	1.724e-284	915.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
GNS2_k127_9789170_7	382464.ABSI01000021_gene373	1.338e-11	68.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,2IURJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
GNS2_k127_9789170_5	401526.TcarDRAFT_2750	5.604e-88	302.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,4H2FP@909932|Negativicutes	909932|Negativicutes	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
GNS2_k127_9789170_4	264732.Moth_1517	1.615e-157	511.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GNS2_k127_9789170_2	1379698.RBG1_1C00001G0054	3.925e-196	617.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
GNS2_k127_9789170_0	1121920.AUAU01000017_gene1239	3.368e-260	814.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
GNS2_k127_9789170_1	469383.Cwoe_1088	9.867e-200	630.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GNS2_k127_9789170_3	186497.PF0547	3.552e-185	588.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
GNS2_k127_9789170_6	368407.Memar_0247	9.062e-24	110.0	COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the carbamate kinase family	cpkA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GNS2_k127_9791030_2	1232410.KI421428_gene1212	4.584e-29	130.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,43S9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GNS2_k127_9791030_0	909663.KI867150_gene1676	6.082e-96	319.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GNS2_k127_9791030_1	443144.GM21_3060	2.122e-90	316.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GNS2_k127_9791030_3	1047013.AQSP01000099_gene1496	7.52e-12	79.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.64,2.C.1.2	-	-	MttA_Hcf106
GNS2_k127_979545_0	204669.Acid345_4231	3.352e-198	645.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
GNS2_k127_979545_2	1163409.UUA_12540	1.776e-22	111.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,1X4FD@135614|Xanthomonadales	135614|Xanthomonadales	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GNS2_k127_979545_1	1382359.JIAL01000001_gene2101	1.502e-42	158.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GNS2_k127_9811667_3	1198114.AciX9_3623	1.095e-66	244.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GNS2_k127_9811667_1	1047013.AQSP01000034_gene1652	1.742e-126	423.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GNS2_k127_9811667_6	388399.SSE37_25083	2.87e-11	70.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Preprotein translocase subunit (YajC)	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
GNS2_k127_9811667_0	1121430.JMLG01000017_gene285	2.235e-129	424.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,260AS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GNS2_k127_9811667_2	867903.ThesuDRAFT_00685	4.054e-109	365.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GNS2_k127_9811667_5	204669.Acid345_4036	2.288e-32	142.0	COG0561@1|root,COG0561@2|Bacteria,3Y4J5@57723|Acidobacteria,2JJB7@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
GNS2_k127_9811667_4	246197.MXAN_4676	1.073e-53	194.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
GNS2_k127_9816678_2	264732.Moth_0371	9.793e-46	181.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GNS2_k127_9816678_3	234267.Acid_7893	1.151e-40	159.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019,ko:K13292	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GNS2_k127_9816678_1	1307759.JOMJ01000003_gene2003	1.5e-115	384.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2M98J@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
GNS2_k127_9816678_0	525904.Tter_2810	3.498e-116	385.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GNS2_k127_992290_0	234267.Acid_3505	2.77e-134	440.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
GNS2_k127_992290_1	671143.DAMO_1669	4.68e-74	274.0	COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5
GNS2_k127_992290_3	1127673.GLIP_2482	5.976e-11	74.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM26,CBM_2,CBM_5_12_2,Cytochrome_CBB3,GSDH,He_PIG,PA14,PSCyt3,PSD2,PSD3,PSD4,PSD5
GNS2_k127_992290_2	861299.J421_0888	3.249e-57	206.0	COG3622@1|root,COG3622@2|Bacteria,1ZT2P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GNS2_k127_995657_0	861299.J421_0058	1.275e-122	406.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GNS2_k127_995657_2	682795.AciX8_1892	6.105e-33	146.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria,2JMDU@204432|Acidobacteriia	204432|Acidobacteriia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GNS2_k127_995657_1	1121920.AUAU01000013_gene1712	2.594e-105	356.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GNS2_k127_995657_3	1121920.AUAU01000013_gene1712	2.848e-05	47.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
## 2654 queries scanned
## Total time (seconds): 72.26327419281006
## Rate: 36.73 q/s