## Tue Feb 17 03:33:30 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/GZD2_bin.59.fa -m mmseqs --output GZD2_bin.59 --output_dir /data/result/bins/wyx/eggqs50+/GZD2_bin.59 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GZD2_k127_1001644_5	1128421.JAGA01000003_gene3260	1.716e-44	190.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_1001644_1	179408.Osc7112_5903	1.098e-133	485.0	COG0517@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHWS@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_9,Response_reg
GZD2_k127_1001644_6	926550.CLDAP_13880	7.222e-43	171.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768,ko:K20977	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00820	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HATPase_c_2,HisKA,Response_reg,SpoIIE
GZD2_k127_1001644_4	926550.CLDAP_25540	1.333e-49	185.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_1001644_2	316274.Haur_1474	2.014e-127	415.0	COG3437@1|root,COG3437@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
GZD2_k127_1001644_0	357808.RoseRS_3341	5.346e-200	635.0	COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate lyase	-	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
GZD2_k127_1001644_3	357808.RoseRS_3397	1.951e-69	237.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,3767X@32061|Chloroflexia	32061|Chloroflexia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD2_k127_1006449_1	926569.ANT_18700	2.03e-124	437.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GZD2_k127_1006449_0	926569.ANT_22870	3.914e-182	579.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
GZD2_k127_1006449_2	926569.ANT_20800	3.722e-94	319.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi	200795|Chloroflexi	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1006449_4	1499967.BAYZ01000156_gene551	1.803e-27	115.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
GZD2_k127_1006449_6	926569.ANT_19750	1.09e-06	51.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GZD2_k127_1006449_3	926550.CLDAP_20430	3.268e-67	237.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
GZD2_k127_1006449_5	926569.ANT_19890	1.013e-10	64.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
GZD2_k127_1038539_3	926569.ANT_03320	4.062e-53	188.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GZD2_k127_1038539_2	41431.PCC8801_3550	1.608e-67	238.0	COG0500@1|root,COG2226@2|Bacteria,1G29I@1117|Cyanobacteria,3KHT9@43988|Cyanothece	1117|Cyanobacteria	Q	PFAM Methyltransferase type 11	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
GZD2_k127_1038539_0	383372.Rcas_1549	4.324e-227	711.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
GZD2_k127_1038539_1	926569.ANT_03290	1.475e-140	451.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GZD2_k127_1045860_3	941449.dsx2_2915	2.573e-12	66.0	COG4986@1|root,COG4986@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	opuAB	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GZD2_k127_1045860_1	926569.ANT_07580	6.203e-194	613.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2G5P9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K02049,ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00188,M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17,3.A.1.17.2	-	-	AAA_assoc_C,ABC_tran
GZD2_k127_1045860_2	1121456.ATVA01000019_gene1268	3.397e-79	287.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
GZD2_k127_1045860_0	926569.ANT_13210	3.738e-235	732.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1050757_2	926569.ANT_19370	3.941e-83	287.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GZD2_k127_1050757_3	742767.HMPREF9456_00665	2.343e-31	139.0	28MUJ@1|root,32ZXP@2|Bacteria,4P1S1@976|Bacteroidetes,2FWAP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1050757_0	926569.ANT_30960	2.273e-127	413.0	COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi	200795|Chloroflexi	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676,ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
GZD2_k127_1050757_1	926569.ANT_30970	8.209e-93	309.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi	200795|Chloroflexi	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
GZD2_k127_1050757_4	439292.Bsel_2734	3.854e-16	85.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HFWH@91061|Bacilli,26NWJ@186821|Sporolactobacillaceae	91061|Bacilli	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GZD2_k127_1050757_5	1243664.CAVL020000010_gene4530	2.622e-09	68.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,1ZFWF@1386|Bacillus	91061|Bacilli	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GZD2_k127_1050757_6	694430.Natoc_3415	4.328e-05	51.0	COG0589@1|root,arCOG02053@2157|Archaea,2XYAN@28890|Euryarchaeota,23W4X@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD2_k127_1063299_2	886293.Sinac_2020	2.337e-228	714.0	COG0364@1|root,COG0364@2|Bacteria,2IYER@203682|Planctomycetes	203682|Planctomycetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GZD2_k127_1063299_6	941449.dsx2_2407	5.843e-82	277.0	COG1011@1|root,COG1011@2|Bacteria,1Q4QT@1224|Proteobacteria,42ZNN@68525|delta/epsilon subdivisions,2WUXD@28221|Deltaproteobacteria,2MGMT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GZD2_k127_1063299_9	765912.Thimo_2942	2.852e-29	128.0	COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria,1S4SQ@1236|Gammaproteobacteria,1X05Z@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_1063299_8	706587.Desti_2110	7.707e-57	202.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42ZZI@68525|delta/epsilon subdivisions,2WV7V@28221|Deltaproteobacteria,2MRSV@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
GZD2_k127_1063299_0	1340493.JNIF01000004_gene40	2.526e-305	949.0	COG0021@1|root,COG0021@2|Bacteria,3Y38K@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GZD2_k127_1063299_5	330214.NIDE2980	4.845e-132	427.0	COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae	40117|Nitrospirae	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GZD2_k127_1063299_1	926569.ANT_01100	5.809e-247	774.0	COG0008@1|root,COG0008@2|Bacteria,2G827@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
GZD2_k127_1063299_4	937777.Deipe_0903	1.402e-147	481.0	COG1690@1|root,COG1690@2|Bacteria,1WMKR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
GZD2_k127_1063299_7	1121015.N789_13050	2.853e-63	224.0	COG2114@1|root,COG2114@2|Bacteria,1QTA2@1224|Proteobacteria,1S8ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GZD2_k127_1063299_3	926569.ANT_09770	3.328e-198	627.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GZD2_k127_1064568_0	926569.ANT_15860	3.254e-195	628.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
GZD2_k127_1064568_1	1042163.BRLA_c040090	2.955e-26	112.0	COG3502@1|root,COG3502@2|Bacteria,1V8W5@1239|Firmicutes,4HQG5@91061|Bacilli,2708U@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
GZD2_k127_1064568_2	926550.CLDAP_30390	2.544e-20	96.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
GZD2_k127_1066079_0	926569.ANT_17670	4.929e-237	741.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_1069994_4	314345.SPV1_13452	2.011e-14	83.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2376	Methyltransf_23
GZD2_k127_1069994_2	357808.RoseRS_0589	5.345e-89	305.0	COG2199@1|root,COG3706@2|Bacteria,2G64S@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
GZD2_k127_1069994_0	316274.Haur_2761	4.38e-180	579.0	COG0477@1|root,COG0477@2|Bacteria,2G856@200795|Chloroflexi,375QC@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_1069994_3	1267535.KB906767_gene332	6.698e-43	161.0	COG3189@1|root,COG3189@2|Bacteria,3Y88F@57723|Acidobacteria,2JN90@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GZD2_k127_1069994_1	383372.Rcas_4135	1.585e-110	363.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_9,Response_reg
GZD2_k127_107225_0	32057.KB217483_gene9252	2.02e-36	146.0	COG0500@1|root,COG2226@2|Bacteria,1G31G@1117|Cyanobacteria,1HSVK@1161|Nostocales	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD2_k127_107225_1	926569.ANT_01150	1.345e-27	120.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GZD2_k127_1076469_2	926564.KI911760_gene4963	1.408e-23	101.0	2C3CF@1|root,32RRR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
GZD2_k127_1076469_3	1123508.JH636441_gene3020	3.192e-17	87.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1076469_0	1166948.JPZL01000001_gene2635	3.58e-43	173.0	COG0642@1|root,COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4585@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_1076469_1	28072.Nos7524_2637	1.32e-40	153.0	COG4251@1|root,COG4251@2|Bacteria,1G7XH@1117|Cyanobacteria,1HSW9@1161|Nostocales	1117|Cyanobacteria	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
GZD2_k127_1084274_2	926569.ANT_10580	4.073e-28	116.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GZD2_k127_1084274_1	926569.ANT_10570	1.892e-102	337.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GZD2_k127_1084274_0	926569.ANT_10570	7.517e-209	661.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GZD2_k127_1084524_2	926569.ANT_09640	1.332e-64	223.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GZD2_k127_1084524_0	1254432.SCE1572_36630	1.684e-118	389.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MKW@68525|delta/epsilon subdivisions,2WKFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GZD2_k127_1084524_1	926569.ANT_09630	5.571e-70	246.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GZD2_k127_108694_5	515635.Dtur_1406	3.269e-16	90.0	COG1284@1|root,COG1284@2|Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
GZD2_k127_108694_3	1128421.JAGA01000003_gene3171	3.119e-60	221.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
GZD2_k127_108694_2	1120985.AUMI01000002_gene2436	3.061e-82	282.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4H2W7@909932|Negativicutes	909932|Negativicutes	K	regulator, lysr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GZD2_k127_108694_1	1144275.COCOR_02615	6.414e-97	324.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_108694_4	1144275.COCOR_02614	1.72e-20	96.0	COG4272@1|root,COG4272@2|Bacteria	2|Bacteria	S	membrane	ywjH	-	-	-	-	-	-	-	-	-	-	-	DUF1634
GZD2_k127_108694_0	926550.CLDAP_30470	2.489e-134	431.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_1121602_3	926550.CLDAP_40040	8.542e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
GZD2_k127_1121602_4	926569.ANT_19460	8.676e-37	146.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GZD2_k127_1121602_0	926569.ANT_19480	2.588e-299	931.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GZD2_k127_1121602_2	926569.ANT_19490	2.081e-57	204.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GZD2_k127_1121602_1	926550.CLDAP_06320	9.633e-142	457.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_1121602_5	373903.Hore_11320	1.614e-05	53.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25PSP@186801|Clostridia,3WBN8@53433|Halanaerobiales	186801|Clostridia	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_112190_0	926569.ANT_25100	3.851e-168	542.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GZD2_k127_112190_2	706587.Desti_5093	8.838e-78	290.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GZD2_k127_112190_3	1487953.JMKF01000058_gene5079	2.219e-75	259.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GZD2_k127_112190_4	1173021.ALWA01000031_gene2805	4.691e-59	221.0	COG0477@1|root,COG2814@2|Bacteria,1G2N2@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD2_k127_112190_1	926569.ANT_07430	2.578e-122	404.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GZD2_k127_112190_5	402777.KB235903_gene2225	6.041e-35	143.0	28PC1@1|root,2ZC4I@2|Bacteria,1G51C@1117|Cyanobacteria,1HAP2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_112190_6	1499967.BAYZ01000036_gene2414	5.263e-20	95.0	2BK9M@1|root,32EPT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1126773_2	312284.A20C1_06196	2.301e-84	287.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,3UXBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
GZD2_k127_1126773_1	1128421.JAGA01000001_gene2131	2.104e-95	321.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GZD2_k127_1126773_4	1449976.KALB_2006	8.945e-52	196.0	COG0619@1|root,COG0619@2|Bacteria,2HPW5@201174|Actinobacteria,4ECY2@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GZD2_k127_1126773_3	526222.Desal_3522	9.583e-53	196.0	COG3275@1|root,COG3275@2|Bacteria,1PY1H@1224|Proteobacteria,43EPZ@68525|delta/epsilon subdivisions,2X1BK@28221|Deltaproteobacteria,2MFQ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	-
GZD2_k127_1126773_0	1521187.JPIM01000026_gene1158	1.162e-97	329.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,3766P@32061|Chloroflexia	32061|Chloroflexia	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GZD2_k127_1126773_5	1128421.JAGA01000001_gene2151	5.507e-36	141.0	COG1957@1|root,COG1957@2|Bacteria,2NPG1@2323|unclassified Bacteria	2|Bacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GZD2_k127_1135579_4	1382356.JQMP01000003_gene1742	1.278e-40	155.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_1135579_3	377629.TERTU_0320	1.895e-41	164.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,1SC68@1236|Gammaproteobacteria,2PQ3C@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	I	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_1135579_1	926569.ANT_27760	7.116e-71	247.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GZD2_k127_1135579_0	477974.Daud_1416	6.018e-111	365.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,260A5@186807|Peptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GZD2_k127_1135579_2	1254432.SCE1572_17920	1.084e-50	186.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GZD2_k127_1140802_0	383372.Rcas_2663	3.161e-81	279.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
GZD2_k127_1140802_2	404380.Gbem_1954	1.055e-56	201.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42UWE@68525|delta/epsilon subdivisions,2WQ57@28221|Deltaproteobacteria,43V1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD2_k127_1140802_1	357808.RoseRS_3371	2.881e-78	278.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,Response_reg
GZD2_k127_1140802_3	926569.ANT_08030	7.15e-50	194.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GZD2_k127_1141127_1	1128421.JAGA01000003_gene3536	6.416e-100	336.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_1141127_3	344747.PM8797T_01214	7.428e-16	84.0	COG2010@1|root,COG2010@2|Bacteria,2IYHH@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
GZD2_k127_1141127_2	497964.CfE428DRAFT_6673	1.819e-24	106.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GZD2_k127_1141127_4	517722.AEUE01000002_gene2080	4.227e-07	59.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,2K0TA@204457|Sphingomonadales	204457|Sphingomonadales	K	CarD family transcriptional regulator	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
GZD2_k127_1141127_0	926569.ANT_27120	1.619e-173	562.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
GZD2_k127_1145720_1	926569.ANT_29890	6.019e-84	284.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GZD2_k127_1145720_2	926569.ANT_29880	4.025e-56	201.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GZD2_k127_1145720_3	926569.ANT_00330	6.114e-30	128.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD2_k127_1145720_5	305900.GV64_19345	5.779e-07	57.0	2DNWD@1|root,32ZI4@2|Bacteria,1NF7C@1224|Proteobacteria,1SFR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pilus assembly protein PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GZD2_k127_1145720_6	1121272.KB903252_gene920	1.638e-05	57.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Peptidase_C14,TIR_2,TPR_10,WD40
GZD2_k127_1145720_4	439375.Oant_1218	1.159e-17	97.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,1J1M8@118882|Brucellaceae	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GZD2_k127_1145720_0	497964.CfE428DRAFT_2520	4.385e-103	345.0	COG1215@1|root,COG1215@2|Bacteria,46SF7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
GZD2_k127_1146319_3	485913.Krac_2415	2.097e-96	325.0	COG1216@1|root,COG1216@2|Bacteria,2G8VQ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_1146319_5	937777.Deipe_2800	1.37e-91	309.0	COG1215@1|root,COG1215@2|Bacteria,1WMDM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_1146319_4	926569.ANT_09260	1.23e-92	309.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1146319_1	243231.GSU2483	1.283e-294	929.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
GZD2_k127_1146319_9	1151126.AQYI01000006_gene3363	7.523e-11	75.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4FKWB@85023|Microbacteriaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_1146319_7	1458357.BG58_18700	5.935e-69	241.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1146319_10	1009370.ALO_09679	6.172e-07	60.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,4H2EB@909932|Negativicutes	909932|Negativicutes	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
GZD2_k127_1146319_6	1120999.JONM01000001_gene1346	3.146e-69	239.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2VQ72@28216|Betaproteobacteria,2KR4M@206351|Neisseriales	206351|Neisseriales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
GZD2_k127_1146319_0	448385.sce1353	4.255e-301	937.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
GZD2_k127_1146319_2	671143.DAMO_0410	1.629e-260	815.0	COG2060@1|root,COG2060@2|Bacteria,2NP13@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717	KdpA
GZD2_k127_1146319_11	593750.Metfor_1978	2.758e-06	59.0	COG3187@1|root,arCOG03952@2157|Archaea	2157|Archaea	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
GZD2_k127_1146319_8	351160.RCIX1899	4.39e-22	97.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUT0@28890|Euryarchaeota,2N9J5@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_1149817_4	405948.SACE_4737	9.454e-07	51.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2ICDR@201174|Actinobacteria,4E6UB@85010|Pseudonocardiales	201174|Actinobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
GZD2_k127_1149817_3	35754.JNYJ01000026_gene8819	7.439e-24	116.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4DCEH@85008|Micromonosporales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GZD2_k127_1149817_1	102232.GLO73106DRAFT_00019290	6.066e-43	170.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD2_k127_1149817_2	1382306.JNIM01000001_gene3667	1.257e-30	130.0	COG0671@1|root,COG0671@2|Bacteria,2G7F8@200795|Chloroflexi	200795|Chloroflexi	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GZD2_k127_1149817_0	1499967.BAYZ01000089_gene5053	2.317e-189	601.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
GZD2_k127_115206_1	1382306.JNIM01000001_gene2925	5.936e-42	166.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GZD2_k127_115206_0	903814.ELI_1847	1.971e-125	419.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25UR1@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD2_k127_115206_2	1121335.Clst_0778	3.223e-13	70.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,3WK1G@541000|Ruminococcaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
GZD2_k127_1162805_6	926569.ANT_17820	1.122e-54	194.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GZD2_k127_1162805_1	926569.ANT_09680	1.362e-184	598.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GZD2_k127_1162805_5	926569.ANT_09670	2.771e-92	307.0	COG1941@1|root,COG1941@2|Bacteria,2G6MH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.12.1.2,1.8.98.5	ko:K14128,ko:K18007	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
GZD2_k127_1162805_0	926569.ANT_09660	1.417e-251	781.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
GZD2_k127_1162805_9	1166018.FAES_2826	3.163e-36	144.0	COG0517@1|root,COG0517@2|Bacteria,4PM6K@976|Bacteroidetes,47YG9@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GZD2_k127_1162805_7	926569.ANT_09650	4.617e-42	160.0	COG0680@1|root,COG0680@2|Bacteria,2G9H7@200795|Chloroflexi	200795|Chloroflexi	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1162805_8	1121091.AUMP01000003_gene2690	1.661e-36	143.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_1162805_12	1185876.BN8_04455	4.811e-31	127.0	COG2905@1|root,COG2905@2|Bacteria,4NP1Y@976|Bacteroidetes,47PPN@768503|Cytophagia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GZD2_k127_1162805_4	926569.ANT_12110	5.979e-139	458.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
GZD2_k127_1162805_3	926569.ANT_12100	1.592e-157	514.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
GZD2_k127_1162805_2	926569.ANT_12080	4.027e-176	565.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
GZD2_k127_1162805_10	926550.CLDAP_23690	2.35e-34	137.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GZD2_k127_1162805_13	309801.trd_A0739	7.16e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GZD2_k127_1162805_16	62928.azo1364	1.875e-08	61.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,2KVQ8@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_1162805_11	383372.Rcas_0430	1.06e-33	138.0	2E64T@1|root,330TJ@2|Bacteria,2G93I@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1162805_17	929562.Emtol_3724	7.159e-07	60.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,47YE8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1162805_14	926560.KE387023_gene1958	1.091e-21	102.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1162805_15	1192034.CAP_7816	1.595e-09	69.0	29X8Q@1|root,30IY3@2|Bacteria,1QZTR@1224|Proteobacteria,43CNP@68525|delta/epsilon subdivisions,2X7VZ@28221|Deltaproteobacteria,2YYEQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1164669_3	1444712.BN1013_00368	2.014e-05	52.0	2ENCP@1|root,33G06@2|Bacteria,2JHC7@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1164669_0	402777.KB235903_gene853	1.047e-183	591.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD2_k127_1164669_1	102232.GLO73106DRAFT_00011930	5.842e-85	294.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_1164669_2	742767.HMPREF9456_01660	5.359e-75	255.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GZD2_k127_116501_0	1123248.KB893385_gene4880	5.264e-70	243.0	COG1028@1|root,COG1028@2|Bacteria,4NGAH@976|Bacteroidetes	976|Bacteroidetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GZD2_k127_116501_1	67315.JOBD01000021_gene34	4.026e-66	236.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
GZD2_k127_1183349_0	1121430.JMLG01000003_gene565	7.924e-126	420.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,260CB@186807|Peptococcaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GZD2_k127_1183349_1	926569.ANT_30540	4.558e-119	398.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1183349_2	926569.ANT_01590	1.414e-100	342.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
GZD2_k127_1189705_1	340099.Teth39_2055	5.667e-140	456.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,42FMZ@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GZD2_k127_1189705_2	525904.Tter_2656	9.066e-94	322.0	COG1940@1|root,COG1940@2|Bacteria,2NPF7@2323|unclassified Bacteria	2|Bacteria	GK	Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,MarR_2,ROK
GZD2_k127_1189705_0	926569.ANT_17130	1.438e-150	485.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
GZD2_k127_1189705_3	926569.ANT_17120	1.09e-81	274.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
GZD2_k127_1197720_0	926569.ANT_23740	1.928e-127	415.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_1197720_2	926569.ANT_23730	1.961e-80	272.0	COG0131@1|root,COG0693@1|root,COG0131@2|Bacteria,COG0693@2|Bacteria,2G6JA@200795|Chloroflexi	200795|Chloroflexi	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
GZD2_k127_1197720_4	436114.SYO3AOP1_0318	7.383e-61	216.0	COG0118@1|root,COG0118@2|Bacteria,2G3XA@200783|Aquificae	200783|Aquificae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GZD2_k127_1197720_3	926569.ANT_23710	5.467e-75	261.0	COG0106@1|root,COG0106@2|Bacteria,2G6EC@200795|Chloroflexi	200795|Chloroflexi	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GZD2_k127_1197720_1	1158318.ATXC01000001_gene1314	6.831e-112	366.0	COG0107@1|root,COG0107@2|Bacteria,2G3N6@200783|Aquificae	200783|Aquificae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
GZD2_k127_1197720_5	420246.GTNG_3020	2.856e-45	166.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,1WFH5@129337|Geobacillus	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
GZD2_k127_1197720_7	926569.ANT_23680	5.344e-27	113.0	COG0140@1|root,COG0140@2|Bacteria,2G9QR@200795|Chloroflexi	200795|Chloroflexi	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
GZD2_k127_1197720_6	28532.XP_010555542.1	1.999e-44	165.0	COG0137@1|root,KOG1706@2759|Eukaryota,37QUX@33090|Viridiplantae,3G8Y6@35493|Streptophyta,3HYQY@3699|Brassicales	35493|Streptophyta	E	argininosuccinate synthase	-	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
GZD2_k127_1204423_3	402777.KB235904_gene3327	6.716e-19	94.0	2ECWT@1|root,30T28@2|Bacteria,1GDVQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1204423_2	266117.Rxyl_3167	1.009e-35	141.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
GZD2_k127_1204423_1	1056816.JAFQ01000004_gene4892	1.906e-42	168.0	COG0122@1|root,COG0122@2|Bacteria,2IEBZ@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1204423_4	1408323.JQKK01000011_gene379	4.772e-07	62.0	2CIJ8@1|root,2ZPKS@2|Bacteria,1UH96@1239|Firmicutes,25PYZ@186801|Clostridia,27IHS@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GZD2_k127_1204423_0	1173022.Cri9333_2777	1.966e-109	364.0	COG0726@1|root,COG0726@2|Bacteria,1G0GG@1117|Cyanobacteria	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD2_k127_1210246_12	1121930.AQXG01000007_gene490	4.608e-12	74.0	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1210246_2	448385.sce5395	4.363e-157	501.0	COG3173@1|root,COG3173@2|Bacteria,1QPYD@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD2_k127_1210246_1	448385.sce5396	1.629e-188	598.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,42SB3@68525|delta/epsilon subdivisions,2X5H5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GZD2_k127_1210246_7	926550.CLDAP_25060	4.953e-35	140.0	COG0406@1|root,COG0406@2|Bacteria,2G9HA@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Phosphoglycerate mutase	-	-	5.4.2.11,5.4.2.12	ko:K01834,ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GZD2_k127_1210246_6	926569.ANT_31270	2.803e-36	153.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
GZD2_k127_1210246_0	926569.ANT_31260	7.246e-234	731.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GZD2_k127_1210246_9	1123508.JH636454_gene5778	3.145e-31	129.0	COG2503@1|root,COG4639@1|root,COG2503@2|Bacteria,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
GZD2_k127_1210246_10	316274.Haur_2641	2.127e-30	127.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_1210246_5	867845.KI911784_gene3104	8.448e-68	233.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GZD2_k127_1210246_3	1500306.JQLA01000034_gene3333	4.82e-125	404.0	COG2267@1|root,COG2267@2|Bacteria,1QTYM@1224|Proteobacteria,2U2UP@28211|Alphaproteobacteria,4B7J8@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
GZD2_k127_1210246_4	926569.ANT_00400	9.85e-91	310.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1210246_8	926569.ANT_00390	1.441e-33	134.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
GZD2_k127_121898_1	1128421.JAGA01000003_gene3642	4.823e-46	172.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
GZD2_k127_121898_2	289376.THEYE_A1015	5.067e-45	170.0	COG0801@1|root,COG0801@2|Bacteria,3J19N@40117|Nitrospirae	40117|Nitrospirae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
GZD2_k127_121898_0	926550.CLDAP_33380	1.528e-108	384.0	COG3903@1|root,COG3903@2|Bacteria,2G64X@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,HTH_3,HTH_31,NB-ARC,TPR_12
GZD2_k127_121898_4	1552123.EP57_01470	1.081e-12	74.0	2C5NY@1|root,340BZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_121898_3	1333998.M2A_2996	8.872e-45	166.0	COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria,4BSEB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
GZD2_k127_121898_5	391625.PPSIR1_28836	0.0001037	51.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	391625.PPSIR1_28836|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_122589_1	926569.ANT_02710	5.361e-81	277.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
GZD2_k127_122589_4	1172180.KB911781_gene4605	2.428e-24	111.0	COG2306@1|root,COG2306@2|Bacteria,2GJP9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
GZD2_k127_122589_0	357808.RoseRS_3310	5.545e-227	717.0	COG0366@1|root,COG0366@2|Bacteria,2G7K6@200795|Chloroflexi,374W8@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
GZD2_k127_122589_5	509635.N824_29445	9.37e-13	73.0	COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1ITM0@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome b5-like Heme Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
GZD2_k127_122589_2	489825.LYNGBM3L_63070	1.075e-41	162.0	28PC1@1|root,2ZC4I@2|Bacteria,1G51C@1117|Cyanobacteria,1HAP2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_122589_3	1227360.C176_19549	9.238e-35	139.0	COG3797@1|root,COG3797@2|Bacteria,1V4KG@1239|Firmicutes,4HIGT@91061|Bacilli,26IKV@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GZD2_k127_1226903_17	765420.OSCT_1900	3.093e-32	128.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GZD2_k127_1226903_2	867845.KI911784_gene2295	1.979e-158	509.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
GZD2_k127_1226903_19	706587.Desti_5608	1.829e-16	83.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD2_k127_1226903_11	324602.Caur_2455	1.121e-72	252.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
GZD2_k127_1226903_5	485916.Dtox_2814	1.934e-91	315.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GZD2_k127_1226903_1	338969.Rfer_0358	2.08e-183	582.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_1226903_12	1123073.KB899242_gene950	1.833e-69	251.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1X53Q@135614|Xanthomonadales	135614|Xanthomonadales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GZD2_k127_1226903_16	189753.AXAS01000002_gene5413	4.811e-39	157.0	COG3391@1|root,COG3391@2|Bacteria,1RFWG@1224|Proteobacteria,2U7T8@28211|Alphaproteobacteria,3K2MV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1226903_9	338969.Rfer_0357	1.323e-79	271.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
GZD2_k127_1226903_10	192952.MM_3243	5.888e-77	267.0	arCOG06746@1|root,arCOG06746@2157|Archaea,2Y5GC@28890|Euryarchaeota	28890|Euryarchaeota	S	Pfam:DUF422	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
GZD2_k127_1226903_6	926569.ANT_22980	4.09e-87	297.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_1226903_3	926560.KE387023_gene2647	1.294e-121	397.0	COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1226903_0	926569.ANT_15410	0.0	1129.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
GZD2_k127_1226903_15	926569.ANT_11720	1.951e-45	173.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GZD2_k127_1226903_4	926569.ANT_11730	5.97e-109	364.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GZD2_k127_1226903_8	1163407.UU7_04737	1.422e-85	289.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
GZD2_k127_1226903_7	1121422.AUMW01000005_gene665	1.949e-86	292.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,261BM@186807|Peptococcaceae	186801|Clostridia	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
GZD2_k127_1226903_13	321332.CYB_2125	7.608e-55	203.0	COG0765@1|root,COG0765@2|Bacteria,1G0FV@1117|Cyanobacteria,1H13F@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	-	-	-	ko:K02029,ko:K02030,ko:K09971,ko:K17062	ko02010,map02010	M00232,M00236,M00587	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.12,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1,SBP_bac_3
GZD2_k127_1226903_14	1122609.AUGT01000002_gene3996	2.222e-53	200.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GZD2_k127_1226903_18	926569.ANT_14650	2.057e-24	106.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD2_k127_1233211_2	112098.XP_008610717.1	2.343e-15	91.0	KOG4351@1|root,KOG4351@2759|Eukaryota	2759|Eukaryota	S	ubiquitin binding	-	-	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,ZZ
GZD2_k127_1233211_0	926569.ANT_22190	1.034e-66	259.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_1233211_1	926569.ANT_01990	8.241e-34	152.0	COG4447@1|root,COG4447@2|Bacteria,2G7EF@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1238007_0	926569.ANT_06420	5.949e-85	288.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_125839_2	1499967.BAYZ01000159_gene478	9.348e-38	151.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GZD2_k127_125839_1	1173026.Glo7428_1980	1.275e-124	413.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
GZD2_k127_125839_0	926569.ANT_09430	2.759e-136	440.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GZD2_k127_1263019_8	526227.Mesil_2009	4.362e-35	139.0	COG1506@1|root,COG1506@2|Bacteria,1WI4E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Hydrolase_4,Peptidase_S9
GZD2_k127_1263019_6	926569.ANT_12960	1.42e-50	187.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GZD2_k127_1263019_1	926569.ANT_12940	2.608e-144	469.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
GZD2_k127_1263019_3	517417.Cpar_1290	1.239e-65	232.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
GZD2_k127_1263019_2	926569.ANT_12930	1.034e-82	287.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GZD2_k127_1263019_0	926569.ANT_14570	2.065e-307	963.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
GZD2_k127_1263019_4	287.DR97_5978	8.126e-62	218.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
GZD2_k127_1263019_9	658187.LDG_6943	1.837e-27	122.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
GZD2_k127_1263019_5	357808.RoseRS_3625	1.343e-58	227.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,37567@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD2_k127_1263019_7	926560.KE387023_gene2480	1.116e-44	170.0	COG0346@1|root,COG0346@2|Bacteria,1WMJE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1281061_5	326427.Cagg_1683	8.697e-53	192.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,376NC@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_1281061_7	326427.Cagg_1682	5.312e-32	127.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
GZD2_k127_1281061_10	1121472.AQWN01000006_gene1749	0.0001377	52.0	COG0226@1|root,COG0226@2|Bacteria,1VW5C@1239|Firmicutes,25182@186801|Clostridia,265ED@186807|Peptococcaceae	186801|Clostridia	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GZD2_k127_1281061_2	1408254.T458_17225	3.974e-91	312.0	COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli,26TVQ@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD2_k127_1281061_3	926569.ANT_13070	6.577e-74	257.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
GZD2_k127_1281061_1	316274.Haur_0632	1.846e-146	473.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi,3752Z@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
GZD2_k127_1281061_4	1385935.N836_22535	5.549e-65	235.0	COG5650@1|root,COG5650@2|Bacteria,1G8N1@1117|Cyanobacteria,1HE3U@1150|Oscillatoriales	1117|Cyanobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ALG3
GZD2_k127_1281061_6	445961.IW15_07180	7.359e-44	164.0	COG1673@1|root,COG1673@2|Bacteria,4NRT8@976|Bacteroidetes,1I3EG@117743|Flavobacteriia,3ZSNV@59732|Chryseobacterium	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
GZD2_k127_1281061_9	1047013.AQSP01000108_gene2067	1.218e-14	79.0	2EG8Z@1|root,332XF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1281061_0	926569.ANT_14080	0.0	1263.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GZD2_k127_1286771_3	883080.HMPREF9697_00271	2.417e-31	127.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2TTFS@28211|Alphaproteobacteria,3JSV1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GZD2_k127_1286771_0	926569.ANT_20980	3.921e-109	360.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
GZD2_k127_1286771_2	179408.Osc7112_4977	2.592e-38	147.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria,1HDA0@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_1286771_1	926569.ANT_20970	1.942e-96	321.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K09820,ko:K11710	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
GZD2_k127_1286771_4	1128421.JAGA01000003_gene3096	1.979e-26	111.0	COG0803@1|root,COG0803@2|Bacteria,2NP5U@2323|unclassified Bacteria	2|Bacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
GZD2_k127_128860_3	316274.Haur_1217	2.629e-44	184.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_128860_4	593750.Metfor_2917	4.189e-30	139.0	COG0642@1|root,COG2203@1|root,arCOG02348@1|root,arCOG02349@1|root,arCOG02352@1|root,arCOG02376@1|root,arCOG02385@1|root,arCOG02348@2157|Archaea,arCOG02349@2157|Archaea,arCOG02352@2157|Archaea,arCOG02369@2157|Archaea,arCOG02376@2157|Archaea,arCOG02385@2157|Archaea,arCOG06193@2157|Archaea,2Y7U3@28890|Euryarchaeota,2NAXF@224756|Methanomicrobia	224756|Methanomicrobia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_9,Response_reg
GZD2_k127_128860_2	439235.Dalk_0779	3.326e-66	253.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2MIVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
GZD2_k127_128860_0	1313172.YM304_01530	1.082e-102	346.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
GZD2_k127_128860_1	926569.ANT_28000	2.698e-73	275.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
GZD2_k127_128860_5	228405.HNE_3093	4.888e-07	58.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,43XBR@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1304716_1	926569.ANT_30910	1.664e-104	345.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD2_k127_1304716_0	926569.ANT_30900	5.955e-127	413.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GZD2_k127_1304716_5	118166.JH976537_gene552	3.829e-65	245.0	COG0747@1|root,COG0747@2|Bacteria,1G0S3@1117|Cyanobacteria,1H75X@1150|Oscillatoriales	1117|Cyanobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_1304716_2	324602.Caur_2783	4.454e-79	276.0	COG0601@1|root,COG0601@2|Bacteria,2G662@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD2_k127_1304716_4	324602.Caur_2782	1.323e-78	273.0	COG1173@1|root,COG1173@2|Bacteria,2G853@200795|Chloroflexi	200795|Chloroflexi	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GZD2_k127_1304716_3	926550.CLDAP_22060	1.114e-78	278.0	COG0438@1|root,COG0438@2|Bacteria,2G8P6@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_1304716_7	926550.CLDAP_37480	1.469e-26	117.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yohD	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944	3.6.1.27,4.1.3.25	ko:K03975,ko:K18292,ko:K19302	ko00550,ko00660,ko01100,map00550,map00660,map01100	-	R00237,R05627	RC00002,RC00502,RC01205	ko00000,ko00001,ko01000,ko01011	-	-	-	Rhodanese,SNARE_assoc
GZD2_k127_1304716_6	111780.Sta7437_2869	1.61e-62	237.0	COG3210@1|root,COG3942@1|root,COG3210@2|Bacteria,COG3942@2|Bacteria,1GJ0Q@1117|Cyanobacteria,3VN4K@52604|Pleurocapsales	1117|Cyanobacteria	U	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1306239_8	926569.ANT_03090	7.517e-27	114.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GZD2_k127_1306239_3	926569.ANT_17990	2.336e-80	273.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GZD2_k127_1306239_6	926569.ANT_18000	4.857e-35	136.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GZD2_k127_1306239_7	525904.Tter_0983	1.001e-32	140.0	COG0671@1|root,COG0671@2|Bacteria,2NQ8J@2323|unclassified Bacteria	2|Bacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GZD2_k127_1306239_5	926569.ANT_15430	4.829e-68	237.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
GZD2_k127_1306239_9	926569.ANT_27650	7.001e-26	111.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD2_k127_1306239_1	864051.BurJ1DRAFT_2684	9.381e-251	779.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria,1KN5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
GZD2_k127_1306239_0	864051.BurJ1DRAFT_2685	0.0	1133.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GZD2_k127_1306239_4	864051.BurJ1DRAFT_2686	2.689e-80	271.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GZD2_k127_1306239_2	864051.BurJ1DRAFT_2687	2.601e-96	319.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2VWMP@28216|Betaproteobacteria,1KNZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
GZD2_k127_1307646_2	104623.Ser39006_02027	1.514e-56	200.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,3ZZN2@613|Serratia	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyfI	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	-	ko:K12144,ko:K14088,ko:K15832	-	-	-	-	ko00000,ko01000	-	-	iECSP_1301.ECSP_3428,iECs_1301.ECs3351	Oxidored_q6
GZD2_k127_1307646_5	1123487.KB892864_gene2152	5.864e-33	133.0	2DBX5@1|root,2ZBMB@2|Bacteria,1RHQ7@1224|Proteobacteria	1224|Proteobacteria	E	Formate hydrogenlyase	hycH	-	-	ko:K12145,ko:K15834	-	-	-	-	ko00000,ko01000	-	-	-	HycH
GZD2_k127_1307646_3	1205683.CAKR01000010_gene3413	9.594e-46	171.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,1S0IE@1236|Gammaproteobacteria,41EXX@629|Yersinia	1236|Gammaproteobacteria	C	hydrogenase 3 maturation protease	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
GZD2_k127_1307646_4	1166018.FAES_2826	1.443e-38	149.0	COG0517@1|root,COG0517@2|Bacteria,4PM6K@976|Bacteroidetes,47YG9@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GZD2_k127_1307646_1	861299.J421_2228	2.992e-84	288.0	COG0702@1|root,COG0702@2|Bacteria,1ZV6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GZD2_k127_1307646_6	1120999.JONM01000001_gene1149	1.358e-14	78.0	COG5485@1|root,COG5485@2|Bacteria,1PYNM@1224|Proteobacteria,2WBUB@28216|Betaproteobacteria,2KTKX@206351|Neisseriales	206351|Neisseriales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GZD2_k127_1307646_0	485913.Krac_7185	2.077e-117	409.0	COG3629@1|root,COG3629@2|Bacteria,2G88E@200795|Chloroflexi	2|Bacteria	K	SPTR Q471D1 TPR repeat Bacterial transcriptional activator domain Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,NACHT,NB-ARC,WD40
GZD2_k127_1310262_5	926550.CLDAP_32470	3.905e-38	153.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_1310262_4	926550.CLDAP_32470	7.301e-86	308.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_1310262_1	316274.Haur_3664	5.97e-244	763.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Arabinose_Iso_C,Arabinose_Isome
GZD2_k127_1310262_2	877411.JMMA01000002_gene1822	7.612e-114	371.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3WH0C@541000|Ruminococcaceae	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
GZD2_k127_1310262_0	926550.CLDAP_04860	1.148e-271	843.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	araB	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD2_k127_1310262_3	316274.Haur_2117	2.503e-97	322.0	COG1172@1|root,COG1172@2|Bacteria,2G8WV@200795|Chloroflexi,377N4@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GZD2_k127_131702_1	105559.Nwat_1654	5.077e-49	186.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria,1WZ9C@135613|Chromatiales	135613|Chromatiales	I	PFAM Diacylglycerol kinase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD2_k127_131702_3	289376.THEYE_A0128	7.689e-06	53.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GZD2_k127_131702_2	660470.Theba_2174	3.236e-22	105.0	2DUHG@1|root,33QNU@2|Bacteria,2GDRM@200918|Thermotogae	200918|Thermotogae	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GZD2_k127_131702_0	867845.KI911784_gene3077	1.282e-66	235.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
GZD2_k127_131702_4	1382306.JNIM01000001_gene294	4.342e-05	49.0	29684@1|root,2ZTI4@2|Bacteria,2G9NR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_133033_3	861299.J421_5775	1.983e-17	94.0	2DSI9@1|root,33G8T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_133033_0	635013.TherJR_2108	1.926e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_133033_1	867845.KI911784_gene617	4.263e-33	140.0	COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_133033_2	1238182.C882_1606	1.734e-28	129.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,2JRK0@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
GZD2_k127_1332673_9	211114.JOEF01000003_gene3012	9.421e-50	181.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GZD2_k127_1332673_7	743722.Sph21_1746	1.374e-57	206.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
GZD2_k127_1332673_0	509191.AEDB02000065_gene705	4.033e-128	418.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,3WI32@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_1332673_6	398512.JQKC01000029_gene4330	4.151e-64	228.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,24B28@186801|Clostridia,3WI3W@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_1332673_3	398512.JQKC01000029_gene4329	1.902e-76	264.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia,3WI8Z@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_1332673_2	926569.ANT_20520	2.462e-100	336.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GZD2_k127_1332673_11	1463934.JOCF01000003_gene2860	2.641e-44	168.0	2CMWR@1|root,33V1U@2|Bacteria,2I81U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1332673_10	926569.ANT_11850	1.572e-44	167.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GZD2_k127_1332673_4	926569.ANT_11840	6.971e-71	241.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD2_k127_1332673_1	926569.ANT_11830	6.232e-113	390.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
GZD2_k127_1332673_8	926569.ANT_11820	3.67e-55	216.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
GZD2_k127_1332673_5	926569.ANT_11800	1.595e-70	259.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_1332673_12	1128427.KB904821_gene2937	3.811e-07	63.0	COG0840@1|root,COG2114@1|root,COG0840@2|Bacteria,COG2114@2|Bacteria,1FZXP@1117|Cyanobacteria,1HH4V@1150|Oscillatoriales	1117|Cyanobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,HAMP,MASE1,PAS,PAS_9,dCache_1
GZD2_k127_1371673_1	667632.KB890175_gene4132	3.915e-75	256.0	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
GZD2_k127_1371673_3	373994.Riv7116_6073	6.665e-37	143.0	COG3265@1|root,COG3265@2|Bacteria,1G60D@1117|Cyanobacteria,1HN2H@1161|Nostocales	1117|Cyanobacteria	F	TIGRFAM carbohydrate kinase, thermoresistant glucokinase family	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
GZD2_k127_1371673_0	926569.ANT_24670	6.598e-158	503.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_1371673_4	1382306.JNIM01000001_gene2128	2.845e-32	132.0	2BHPS@1|root,32BT1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1371673_2	1298880.AUEV01000023_gene5233	7.733e-45	166.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
GZD2_k127_1371673_5	1120956.JHZK01000004_gene1330	9.219e-19	85.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,1JPAT@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_1372363_5	1144319.PMI16_01484	1.154e-25	107.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,474RD@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
GZD2_k127_1372363_6	446470.Snas_6106	3.36e-07	61.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GZD2_k127_1372363_3	225849.swp_4486	2.738e-44	172.0	COG3675@1|root,COG3675@2|Bacteria,1PWRW@1224|Proteobacteria,1SXT0@1236|Gammaproteobacteria,2QE8W@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
GZD2_k127_1372363_2	926569.ANT_19610	1.077e-59	214.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GZD2_k127_1372363_0	926569.ANT_06880	1.033e-124	424.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
GZD2_k127_1372363_1	926569.ANT_03110	6.495e-95	318.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_1372363_4	926569.ANT_03120	1.356e-32	128.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
GZD2_k127_1373169_0	1095769.CAHF01000025_gene672	3.865e-243	758.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,4726R@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD2_k127_1373169_1	1128421.JAGA01000003_gene2877	1.809e-110	366.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2NNSH@2323|unclassified Bacteria	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
GZD2_k127_1373169_3	886293.Sinac_3660	2.386e-69	245.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GZD2_k127_1373169_2	1128421.JAGA01000003_gene2874	1.817e-86	296.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1373829_3	926569.ANT_14000	1.816e-66	230.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
GZD2_k127_1373829_5	926569.ANT_23510	1.539e-62	231.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
GZD2_k127_1373829_0	926569.ANT_00310	1.804e-85	301.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
GZD2_k127_1373829_1	926569.ANT_25090	8.813e-80	280.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1373829_2	926569.ANT_25100	9.796e-78	264.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GZD2_k127_1389406_2	1150474.JQJI01000025_gene1664	1.817e-23	106.0	COG1394@1|root,COG1394@2|Bacteria,2GD6P@200918|Thermotogae	200918|Thermotogae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
GZD2_k127_1389406_1	1144275.COCOR_04108	4.771e-68	237.0	COG2085@1|root,COG2085@2|Bacteria,1NF95@1224|Proteobacteria,4380B@68525|delta/epsilon subdivisions,2X3AC@28221|Deltaproteobacteria,2YURK@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GZD2_k127_1389406_0	926569.ANT_06070	3.835e-147	475.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GZD2_k127_1394893_0	357808.RoseRS_2964	3.443e-259	805.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
GZD2_k127_1394893_3	926569.ANT_02660	6.219e-113	370.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GZD2_k127_1394893_1	926569.ANT_02650	4.605e-131	427.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GZD2_k127_1394893_2	926569.ANT_02640	6.549e-115	377.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GZD2_k127_1394893_4	926569.ANT_02630	7.025e-90	299.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GZD2_k127_1406780_2	926550.CLDAP_36980	2.322e-22	106.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GZD2_k127_1406780_0	658086.HMPREF0994_03756	1.714e-113	381.0	COG1486@1|root,COG1486@2|Bacteria,1V6E5@1239|Firmicutes,24KU5@186801|Clostridia	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
GZD2_k127_1406780_1	1173026.Glo7428_1028	2.122e-42	160.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GZD2_k127_1414469_1	324602.Caur_2120	3.261e-125	408.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_1414469_3	926569.ANT_06280	3.18e-52	189.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
GZD2_k127_1414469_6	1192034.CAP_4647	2.702e-22	105.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.180	ko:K18846	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_1414469_4	266117.Rxyl_2427	7.496e-52	194.0	2DBRF@1|root,2ZAKB@2|Bacteria,2IIVX@201174|Actinobacteria,4CQPW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1414469_5	706587.Desti_5046	7.289e-41	157.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WQCU@28221|Deltaproteobacteria,2MRZZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GZD2_k127_1414469_2	221288.JH992901_gene1075	1.196e-114	385.0	COG4191@1|root,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,1JH5H@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
GZD2_k127_1414469_0	1183438.GKIL_2947	1.751e-199	635.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria	1117|Cyanobacteria	KOT	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
GZD2_k127_1430165_12	1121121.KB894303_gene3000	1.159e-09	59.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,271FG@186822|Paenibacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GZD2_k127_1430165_0	926569.ANT_02690	2.082e-245	766.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
GZD2_k127_1430165_1	926569.ANT_09020	5.266e-156	503.0	COG0477@1|root,COG2814@2|Bacteria,2G8W5@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_1430165_11	246197.MXAN_7399	1.257e-15	88.0	COG1723@1|root,COG1723@2|Bacteria,1R8R9@1224|Proteobacteria,42W7V@68525|delta/epsilon subdivisions,2WS5C@28221|Deltaproteobacteria,2YZMK@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1430165_7	1122129.AUEF01000031_gene2284	4.504e-46	181.0	2CH8Y@1|root,32S5K@2|Bacteria,1VDN2@1239|Firmicutes,4HMAK@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1430165_6	208596.CAR_c06000	4.104e-48	184.0	2CH8Y@1|root,32S5K@2|Bacteria,1VDN2@1239|Firmicutes,4HMAK@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1430165_8	1286631.X805_15040	8.184e-42	159.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
GZD2_k127_1430165_5	926569.ANT_19230	1.836e-52	194.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GZD2_k127_1430165_13	3880.AES87815	0.0001777	46.0	2D08W@1|root,2SD7U@2759|Eukaryota,37XFR@33090|Viridiplantae,3GMII@35493|Streptophyta	35493|Streptophyta	C	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	psbM	-	-	ko:K02714	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbM
GZD2_k127_1430165_9	292459.STH551	1.243e-33	138.0	2BZ6R@1|root,332GN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1430165_4	649638.Trad_0655	1.284e-56	212.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1
GZD2_k127_1430165_3	189425.PGRAT_04865	2.989e-81	280.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HE6Z@91061|Bacilli,2758P@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GZD2_k127_1430165_2	1521187.JPIM01000026_gene1158	1.846e-85	294.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,3766P@32061|Chloroflexia	32061|Chloroflexia	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GZD2_k127_1434910_1	357808.RoseRS_0452	3.294e-55	201.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GZD2_k127_1434910_2	357808.RoseRS_0453	5.688e-50	183.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GZD2_k127_1434910_0	316274.Haur_3362	4.72e-95	321.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GZD2_k127_1434910_3	926569.ANT_26490	1.25e-30	124.0	COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
GZD2_k127_1443099_4	554065.XP_005844106.1	9.216e-08	58.0	COG0123@1|root,KOG1343@2759|Eukaryota,37N54@33090|Viridiplantae,34JFX@3041|Chlorophyta	3041|Chlorophyta	B	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GZD2_k127_1443099_1	926569.ANT_01320	2.39e-30	125.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi	200795|Chloroflexi	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
GZD2_k127_1443099_0	926569.ANT_00200	2.371e-130	427.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GZD2_k127_1469309_3	926569.ANT_15960	3.62e-44	162.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
GZD2_k127_1469309_2	926569.ANT_15970	1.02e-47	175.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GZD2_k127_1469309_0	926569.ANT_15980	1.975e-68	244.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1469309_1	861299.J421_6055	1.001e-64	225.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
GZD2_k127_1469812_2	1298867.AUES01000006_gene300	1.096e-46	173.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,3JV5Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
GZD2_k127_1469812_4	797210.Halxa_3869	1.687e-30	132.0	arCOG04549@1|root,arCOG04549@2157|Archaea,2XW9I@28890|Euryarchaeota,23UGB@183963|Halobacteria	183963|Halobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
GZD2_k127_1469812_5	35754.JNYJ01000075_gene8651	8.748e-26	112.0	COG3474@1|root,COG3474@2|Bacteria,2HB9W@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GZD2_k127_1469812_1	452637.Oter_4137	1.722e-49	189.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
GZD2_k127_1469812_3	861299.J421_0300	1.606e-43	166.0	COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1,COX3
GZD2_k127_1469812_0	876269.ARWA01000001_gene1472	2.061e-86	292.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,3N9N3@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	ctaD	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD2_k127_149551_4	1313172.YM304_01540	4.581e-27	112.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_149551_5	1313172.YM304_01540	3.553e-16	81.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_149551_3	1487923.DP73_12470	8.55e-99	335.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,24DRF@186801|Clostridia,2646E@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_149551_0	926569.ANT_04690	1.808e-171	541.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_149551_1	926569.ANT_04700	3.787e-164	524.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_149551_2	926569.ANT_04710	5.939e-133	431.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GZD2_k127_150008_0	926569.ANT_17480	2.577e-78	263.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
GZD2_k127_150008_1	1265502.KB905954_gene415	3.013e-77	263.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,4ABHT@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_150008_2	264462.Bd3476	2.778e-73	259.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2MTST@213481|Bdellovibrionales,2WQCC@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GZD2_k127_150008_3	1469613.JT55_16070	9.229e-23	113.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
GZD2_k127_150008_4	1034769.KB910518_gene4334	1.023e-08	66.0	COG1807@1|root,COG1807@2|Bacteria,1UZUR@1239|Firmicutes,4HWIA@91061|Bacilli,26T7F@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_1526865_3	926569.ANT_23540	4.826e-49	184.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GZD2_k127_1526865_8	237368.SCABRO_01122	0.0002762	46.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GZD2_k127_1526865_7	237368.SCABRO_01122	1.142e-16	83.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GZD2_k127_1526865_2	314345.SPV1_07149	4.053e-102	350.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria	1224|Proteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
GZD2_k127_1526865_6	1121324.CLIT_13c00200	5.463e-19	97.0	COG5607@1|root,COG5607@2|Bacteria,1U4WY@1239|Firmicutes,2510S@186801|Clostridia	186801|Clostridia	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
GZD2_k127_1526865_5	1340493.JNIF01000003_gene3925	1.118e-23	107.0	COG2062@1|root,COG2062@2|Bacteria,3Y5YQ@57723|Acidobacteria	57723|Acidobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
GZD2_k127_1526865_0	1303518.CCALI_00492	3.022e-210	676.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GZD2_k127_1526865_1	926569.ANT_01750	3.148e-119	395.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
GZD2_k127_1526865_4	926569.ANT_01760	4.047e-40	151.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1531718_1	926569.ANT_06210	2.686e-54	193.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
GZD2_k127_1531718_2	926569.ANT_06190	9.53e-24	101.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
GZD2_k127_1531718_3	1123508.JH636439_gene568	8.92e-05	53.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GZD2_k127_1531718_0	926569.ANT_06180	5.547e-101	346.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_1538094_4	56780.SYN_02669	4.274e-25	112.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42QJJ@68525|delta/epsilon subdivisions,2X5IG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851,ko:K13007	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GZD2_k127_1538094_2	926569.ANT_10900	7.511e-72	249.0	COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
GZD2_k127_1538094_5	373994.Riv7116_4830	5.32e-15	88.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HKN5@1161|Nostocales	1117|Cyanobacteria	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
GZD2_k127_1538094_1	1131730.BAVI_08821	1.356e-81	280.0	COG0702@1|root,COG0702@2|Bacteria,1UNU6@1239|Firmicutes	1239|Firmicutes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1538094_0	56780.SYN_02685	3.626e-149	482.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2MR6Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_1538094_3	926569.ANT_28790	1.195e-44	164.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
GZD2_k127_155551_1	1382306.JNIM01000001_gene1149	9.118e-42	156.0	COG1092@1|root,COG1092@2|Bacteria,2G60G@200795|Chloroflexi	200795|Chloroflexi	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GZD2_k127_155551_3	266117.Rxyl_1005	7.383e-26	123.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_155551_0	926569.ANT_13760	8.495e-58	207.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GZD2_k127_155551_2	1042163.BRLA_c012760	3.211e-37	142.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,4HGM3@91061|Bacilli,26SYI@186822|Paenibacillaceae	91061|Bacilli	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GZD2_k127_1565529_1	1382356.JQMP01000004_gene624	2.081e-47	180.0	COG0747@1|root,COG0747@2|Bacteria,2G860@200795|Chloroflexi,27XM9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_1565529_2	383372.Rcas_2446	1.217e-07	55.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1565529_0	1382306.JNIM01000001_gene3281	2.147e-103	351.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
GZD2_k127_1565529_3	1487953.JMKF01000059_gene4863	3.72e-06	50.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,NB-ARC,Pentapeptide,WD40
GZD2_k127_1584392_5	211114.JOEF01000003_gene3012	8.283e-69	241.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GZD2_k127_1584392_4	41431.PCC8801_0885	2.967e-94	321.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.1.1.72,2.7.1.15,2.7.1.4	ko:K00571,ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000,ko02048	-	-	-	PfkB
GZD2_k127_1584392_0	1487923.DP73_19985	6.258e-176	564.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GZD2_k127_1584392_7	926569.ANT_10410	5.588e-41	155.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GZD2_k127_1584392_3	926569.ANT_10420	6.663e-101	342.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GZD2_k127_1584392_6	926569.ANT_10430	7.74e-44	165.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD2_k127_1584392_8	926550.CLDAP_08800	8.72e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GZD2_k127_1584392_2	161156.JQKW01000009_gene1593	2.548e-131	445.0	COG1009@1|root,COG1009@2|Bacteria,2GHMS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CP	NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GZD2_k127_1584392_1	926569.ANT_10460	2.773e-139	450.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GZD2_k127_1592928_1	91604.ID47_06630	5.923e-71	253.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,47F5S@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
GZD2_k127_1592928_0	926569.ANT_30330	1.266e-181	590.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
GZD2_k127_1610148_0	1380370.JIBA01000012_gene3905	7.048e-167	531.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1610148_3	1464048.JNZS01000010_gene5111	3.148e-47	175.0	2D579@1|root,32TID@2|Bacteria,2IMWE@201174|Actinobacteria,4DFF2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1610148_2	479432.Sros_7256	9.688e-49	179.0	2D579@1|root,32TID@2|Bacteria,2IMWE@201174|Actinobacteria,4EK8I@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1610148_1	42256.RradSPS_2869	9.284e-77	263.0	COG1359@1|root,COG1359@2|Bacteria,2IM32@201174|Actinobacteria	201174|Actinobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
GZD2_k127_1627898_4	926569.ANT_23200	1.57e-64	225.0	COG1540@1|root,COG1540@2|Bacteria,2G8DT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
GZD2_k127_1627898_3	1122915.AUGY01000013_gene2804	4.388e-66	237.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,26SC6@186822|Paenibacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
GZD2_k127_1627898_2	391623.TERMP_01041	1.589e-66	233.0	COG2049@1|root,arCOG05809@2157|Archaea,2XUMA@28890|Euryarchaeota,242UF@183968|Thermococci	183968|Thermococci	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
GZD2_k127_1627898_0	926569.ANT_24820	2.331e-155	499.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GZD2_k127_1627898_1	926569.ANT_23120	5.999e-104	346.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GZD2_k127_164183_1	1120971.AUCA01000001_gene1761	8.807e-48	180.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,278S2@186823|Alicyclobacillaceae	91061|Bacilli	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
GZD2_k127_164183_0	926569.ANT_29140	1.058e-98	328.0	COG0730@1|root,COG0730@2|Bacteria,2G6RC@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_164605_3	926569.ANT_02630	3.893e-39	149.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GZD2_k127_164605_1	632245.CLP_1993	1.116e-93	327.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,36DCM@31979|Clostridiaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
GZD2_k127_164605_0	1128421.JAGA01000002_gene1719	1.398e-110	362.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GZD2_k127_164605_2	926569.ANT_27760	5.196e-71	247.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GZD2_k127_164605_4	702450.CUW_2616	1.509e-09	59.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,3VPAI@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
GZD2_k127_1647205_4	1449347.JQLN01000005_gene5156	1.356e-53	204.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,2M1CJ@2063|Kitasatospora	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_1647205_7	543632.JOJL01000047_gene3367	3.606e-12	79.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_1647205_1	926550.CLDAP_16000	7.168e-92	308.0	COG0500@1|root,COG2226@2|Bacteria,2G7XP@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_1647205_6	715226.ABI_24440	1.886e-12	72.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Transglycosylase-associated protein	MA20_19350	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD2_k127_1647205_8	604331.AUHY01000092_gene1000	1.185e-08	64.0	COG1670@1|root,COG1670@2|Bacteria,1WI91@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
GZD2_k127_1647205_2	1122611.KB903984_gene3916	6.34e-61	219.0	COG1266@1|root,COG1266@2|Bacteria,2IRR4@201174|Actinobacteria,4EKIN@85012|Streptosporangiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_1647205_5	1037409.BJ6T_72940	1.857e-53	190.0	COG0251@1|root,COG0251@2|Bacteria,1PEAI@1224|Proteobacteria,2UFF9@28211|Alphaproteobacteria,3K0X0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD2_k127_1647205_3	561230.PC1_1592	2.688e-57	200.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,1S6BE@1236|Gammaproteobacteria,1MSMT@122277|Pectobacterium	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1647205_0	926569.ANT_20420	1.973e-112	370.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GZD2_k127_1651475_3	36080.S2JN20	1.351e-52	191.0	COG2301@1|root,2QQPK@2759|Eukaryota,38GJH@33154|Opisthokonta,3NXCF@4751|Fungi,1GS5X@112252|Fungi incertae sedis	4751|Fungi	F	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
GZD2_k127_1651475_4	234267.Acid_2818	3.16e-33	134.0	2EPXQ@1|root,33HI8@2|Bacteria,3Y5ZD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1651475_2	439235.Dalk_5022	3.098e-62	224.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_1651475_0	565033.GACE_2162	5.346e-127	414.0	COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota,246GU@183980|Archaeoglobi	183980|Archaeoglobi	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD2_k127_1651475_6	1379698.RBG1_1C00001G0504	4.195e-32	129.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GZD2_k127_1651475_5	1128421.JAGA01000002_gene283	3.967e-32	129.0	COG0629@1|root,COG0629@2|Bacteria,2NPUB@2323|unclassified Bacteria	2|Bacteria	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GZD2_k127_1651475_7	926550.CLDAP_34200	8.766e-17	82.0	2E5PY@1|root,330EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1651475_1	324602.Caur_2207	1.167e-96	324.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GZD2_k127_1655450_0	926569.ANT_19970	0.0	1052.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
GZD2_k127_1655450_2	404380.Gbem_1627	1.021e-30	138.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
GZD2_k127_1655450_1	1379698.RBG1_1C00001G1189	2.838e-205	657.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,2NP5W@2323|unclassified Bacteria	2|Bacteria	U	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
GZD2_k127_1655450_4	644282.Deba_2487	2.655e-18	86.0	COG2020@1|root,COG2020@2|Bacteria,1PK64@1224|Proteobacteria,432NT@68525|delta/epsilon subdivisions,2WX82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1657563_3	1047013.AQSP01000144_gene895	7.367e-86	291.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GZD2_k127_1657563_0	926569.ANT_15990	0.0	1138.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GZD2_k127_1657563_2	926569.ANT_16000	1.225e-112	374.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi	200795|Chloroflexi	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GZD2_k127_1657563_1	926569.ANT_16010	4.914e-133	436.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GZD2_k127_1657563_7	926569.ANT_16020	2.939e-48	180.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GZD2_k127_1657563_11	926569.ANT_16030	3.896e-24	104.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GZD2_k127_1657563_8	926569.ANT_16040	9.137e-38	144.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GZD2_k127_1657563_4	326427.Cagg_2708	1.977e-72	259.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_1657563_10	272562.CA_C3419	1.216e-25	114.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,24HII@186801|Clostridia,36FRR@31979|Clostridiaceae	186801|Clostridia	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
GZD2_k127_1657563_5	913865.DOT_0901	5.113e-64	226.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia,263PS@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1657563_9	882083.SacmaDRAFT_5498	1.873e-28	121.0	COG4978@1|root,COG4978@2|Bacteria,2IKYA@201174|Actinobacteria,4E768@85010|Pseudonocardiales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
GZD2_k127_1657563_6	272624.lpg0556	5.24e-62	219.0	2C388@1|root,30ZIR@2|Bacteria,1RFG7@1224|Proteobacteria,1S4CX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1657563_12	357808.RoseRS_0549	9.55e-10	61.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD2_k127_166089_2	1230476.C207_01739	2.653e-29	126.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,3JW0V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
GZD2_k127_166089_3	452652.KSE_70010	2.683e-09	70.0	COG1520@1|root,COG1520@2|Bacteria,2IAHP@201174|Actinobacteria	201174|Actinobacteria	O	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FG-GAP,VCBS
GZD2_k127_166089_1	926569.ANT_28350	2.115e-34	134.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GZD2_k127_166089_0	536227.CcarbDRAFT_4777	3.004e-53	189.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
GZD2_k127_1662962_4	1121930.AQXG01000003_gene2730	1.909e-43	164.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1IQ02@117747|Sphingobacteriia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GZD2_k127_1662962_8	926569.ANT_16980	1.899e-21	94.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GZD2_k127_1662962_5	485913.Krac_1073	7.353e-39	157.0	COG4221@1|root,COG4221@2|Bacteria,2G6TQ@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_1662962_7	443144.GM21_3869	2.09e-29	121.0	2E8MZ@1|root,332ZD@2|Bacteria,1P763@1224|Proteobacteria,432M3@68525|delta/epsilon subdivisions,2WXF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1662962_2	926569.ANT_16730	7.238e-84	284.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GZD2_k127_1662962_1	926569.ANT_16740	1.261e-93	318.0	COG1226@1|root,COG1226@2|Bacteria,2G7EI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
GZD2_k127_1662962_6	926569.ANT_16750	1.886e-36	141.0	COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1662962_3	383372.Rcas_0251	3.544e-74	268.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GZD2_k127_1662962_0	309801.trd_0650	4.405e-126	419.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,27XK4@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
GZD2_k127_1662962_9	926550.CLDAP_01790	4.949e-07	53.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GZD2_k127_1668131_5	604331.AUHY01000023_gene1638	2.828e-71	248.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_1668131_3	1122223.KB890700_gene2058	5.615e-94	326.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_1668131_6	1209989.TepiRe1_0774	1.704e-48	185.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,42GID@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM degV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_1668131_2	1220534.B655_1171	6.604e-99	332.0	COG0451@1|root,arCOG01369@2157|Archaea,2XUDM@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GZD2_k127_1668131_7	926569.ANT_17620	5.427e-47	175.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
GZD2_k127_1668131_4	1122138.AQUZ01000044_gene4502	3.316e-75	265.0	COG0701@1|root,COG0701@2|Bacteria,2HZBT@201174|Actinobacteria	201174|Actinobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
GZD2_k127_1668131_9	926550.CLDAP_36710	1.505e-29	121.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GZD2_k127_1668131_10	1122915.AUGY01000012_gene3916	1.34e-10	66.0	arCOG13956@1|root,33BWW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1668131_0	1128421.JAGA01000003_gene3696	7.107e-197	630.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD2_k127_1668131_1	1282876.BAOK01000001_gene2981	1.303e-114	375.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria,4BRG9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_02360	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_1668131_8	525368.HMPREF0591_4078	1.119e-29	123.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GZD2_k127_1669998_14	357808.RoseRS_0761	2.116e-20	93.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,375EG@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1669998_0	926569.ANT_14230	0.0	1365.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GZD2_k127_1669998_13	644966.Tmar_0530	3.073e-40	158.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25PSQ@186801|Clostridia,3WDR3@538999|Clostridiales incertae sedis	186801|Clostridia	M	TIGRFAM spore coat assembly protein SafA	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_1669998_1	926569.ANT_25420	1.056e-234	732.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GZD2_k127_1669998_5	1128421.JAGA01000001_gene2435	2.704e-126	415.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GZD2_k127_1669998_3	768671.ThimaDRAFT_1778	5.182e-138	446.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
GZD2_k127_1669998_4	926569.ANT_22600	1.469e-126	416.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GZD2_k127_1669998_7	926569.ANT_22610	2.7e-118	389.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GZD2_k127_1669998_10	706587.Desti_1226	2.436e-78	274.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,2MRJT@213462|Syntrophobacterales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GZD2_k127_1669998_2	926569.ANT_22630	2.456e-142	466.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GZD2_k127_1669998_6	926569.ANT_22640	3.148e-120	395.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_1669998_8	926569.ANT_22650	3.938e-98	336.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_1669998_9	926569.ANT_22660	1.021e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_1669998_12	926569.ANT_22670	2.188e-44	164.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi	200795|Chloroflexi	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GZD2_k127_1669998_11	926569.ANT_27450	1.028e-77	272.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
GZD2_k127_1671553_0	926569.ANT_16770	8.448e-75	260.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GZD2_k127_1671553_1	1230338.MOMA_06781	0.0004079	51.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,3NIGQ@468|Moraxellaceae	1236|Gammaproteobacteria	I	synthase III	fabH	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD2_k127_1674333_9	926569.ANT_14870	6.824e-41	153.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GZD2_k127_1674333_12	406124.ACPC01000022_gene4120	1.49e-13	76.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,1ZI2E@1386|Bacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD2_k127_1674333_10	408672.NBCG_04167	4.057e-31	130.0	COG1309@1|root,COG1309@2|Bacteria,2IJ18@201174|Actinobacteria,4DWUE@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD2_k127_1674333_6	926569.ANT_15670	1.712e-58	226.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1674333_14	1160707.AJIK01000017_gene52	9.364e-06	59.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4HAV2@91061|Bacilli,26F62@186818|Planococcaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
GZD2_k127_1674333_5	32057.KB217478_gene6497	1.728e-70	248.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1G3NQ@1117|Cyanobacteria,1HP4J@1161|Nostocales	1117|Cyanobacteria	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
GZD2_k127_1674333_1	1128421.JAGA01000002_gene789	1.817e-262	837.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2NPET@2323|unclassified Bacteria	2|Bacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GZD2_k127_1674333_11	1128421.JAGA01000002_gene867	2.965e-23	112.0	COG1316@1|root,COG1316@2|Bacteria,2NR49@2323|unclassified Bacteria	2|Bacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_1674333_2	926569.ANT_28990	2.106e-180	573.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GZD2_k127_1674333_3	926569.ANT_01600	4.332e-99	333.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
GZD2_k127_1674333_7	926569.ANT_30380	5.57e-55	196.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
GZD2_k127_1674333_0	926569.ANT_31250	0.0	1150.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD2_k127_1674333_8	309799.DICTH_1421	2.822e-54	198.0	COG0164@1|root,COG0164@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GZD2_k127_1674333_4	926569.ANT_00990	9.191e-97	321.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_1674333_15	1220534.B655_2290	0.0001879	53.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y5UU@28890|Euryarchaeota,23PUE@183925|Methanobacteria	183925|Methanobacteria	L	NERD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD
GZD2_k127_1676219_1	420324.KI912026_gene5062	0.0002392	47.0	COG0272@1|root,COG0272@2|Bacteria,1NRR5@1224|Proteobacteria,2TYJC@28211|Alphaproteobacteria,1JZGF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Helix-hairpin-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HHH_4,HHH_5
GZD2_k127_1676219_0	1403819.BATR01000022_gene806	2.338e-165	554.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
GZD2_k127_1687418_6	1128421.JAGA01000002_gene732	1.469e-18	85.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_1687418_0	926560.KE387023_gene3595	9.229e-123	429.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
GZD2_k127_1687418_1	1254432.SCE1572_13190	3.147e-66	239.0	COG2267@1|root,COG2267@2|Bacteria,1NYSN@1224|Proteobacteria,4380J@68525|delta/epsilon subdivisions,2X3AK@28221|Deltaproteobacteria,2YV58@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD2_k127_1687418_2	1297742.A176_00084	9.08e-60	231.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_1687418_4	1300345.LF41_48	1.375e-27	130.0	COG0028@1|root,COG1520@1|root,COG3391@1|root,COG3693@1|root,COG0028@2|Bacteria,COG1520@2|Bacteria,COG3391@2|Bacteria,COG3693@2|Bacteria,1QYUP@1224|Proteobacteria	1224|Proteobacteria	EH	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
GZD2_k127_1687418_3	765420.OSCT_0637	9.486e-40	152.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_1687418_8	926569.ANT_17670	5.136e-12	66.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_1687418_5	86416.Clopa_2530	8.152e-22	99.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,24ADY@186801|Clostridia,36G2E@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS14520	Asp_Glu_race
GZD2_k127_1687418_7	86416.Clopa_2530	2.059e-17	84.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,24ADY@186801|Clostridia,36G2E@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS14520	Asp_Glu_race
GZD2_k127_1692648_2	926569.ANT_28670	8.939e-25	105.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_1692648_0	1173027.Mic7113_0692	7.176e-63	223.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria,1HAWT@1150|Oscillatoriales	1117|Cyanobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GZD2_k127_1692648_1	926569.ANT_28940	5.241e-55	204.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GZD2_k127_169276_1	926569.ANT_08110	9.315e-87	292.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_169276_0	926569.ANT_08120	7.038e-135	440.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi	200795|Chloroflexi	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
GZD2_k127_169276_2	526227.Mesil_0791	8.321e-40	152.0	COG1131@1|root,COG1131@2|Bacteria,1WMG4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
GZD2_k127_1697858_4	575540.Isop_1059	3.105e-06	54.0	COG3596@1|root,COG3597@1|root,COG3596@2|Bacteria,COG3597@2|Bacteria,2IY47@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
GZD2_k127_1697858_6	323261.Noc_1115	5.738e-05	49.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GZD2_k127_1697858_5	1122925.KB895387_gene2807	3.331e-05	46.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1697858_0	926569.ANT_06130	3.522e-97	331.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
GZD2_k127_1697858_2	926569.ANT_03760	2.625e-59	208.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GZD2_k127_1697858_1	926569.ANT_03770	2.218e-87	295.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GZD2_k127_1697858_3	926569.ANT_06590	2.807e-06	51.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD2_k127_1704244_16	1071379.XP_004180804.1	0.00051	51.0	COG1928@1|root,KOG3359@2759|Eukaryota,38DG3@33154|Opisthokonta,3NURN@4751|Fungi,3QN9T@4890|Ascomycota,3RRSH@4891|Saccharomycetes,3RZNA@4893|Saccharomycetaceae	4751|Fungi	O	to Saccharomyces cerevisiae PMT2 (YAL023C) and PMT3 (YOR321W)	PMT2	GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009268,GO:0009628,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0030163,GO:0030447,GO:0031501,GO:0031502,GO:0031505,GO:0031984,GO:0032991,GO:0033554,GO:0034645,GO:0034976,GO:0035268,GO:0035269,GO:0035690,GO:0035966,GO:0035967,GO:0036176,GO:0036177,GO:0036178,GO:0036211,GO:0036503,GO:0040007,GO:0042175,GO:0042221,GO:0042493,GO:0042710,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044010,GO:0044011,GO:0044182,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044764,GO:0045229,GO:0050896,GO:0051603,GO:0051703,GO:0051704,GO:0051716,GO:0051788,GO:0070085,GO:0070887,GO:0071218,GO:0071310,GO:0071554,GO:0071555,GO:0071704,GO:0071712,GO:0071840,GO:0071852,GO:0071944,GO:0090605,GO:0090609,GO:0097502,GO:0097582,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1902494,GO:1990234	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	MIR,PMT,PMT_4TMC
GZD2_k127_1704244_3	926569.ANT_28890	6.521e-74	258.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_1704244_10	526225.Gobs_0746	1.328e-39	169.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
GZD2_k127_1704244_12	1380390.JIAT01000014_gene6037	3.223e-32	131.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4CQVT@84995|Rubrobacteria	84995|Rubrobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
GZD2_k127_1704244_6	926569.ANT_00660	5.057e-69	246.0	COG0287@1|root,COG0287@2|Bacteria,2G9BH@200795|Chloroflexi	200795|Chloroflexi	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GZD2_k127_1704244_13	926569.ANT_00650	6.088e-28	115.0	COG2827@1|root,COG2827@2|Bacteria,2G9H6@200795|Chloroflexi	200795|Chloroflexi	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GZD2_k127_1704244_2	926569.ANT_00640	6.234e-85	285.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GZD2_k127_1704244_14	926569.ANT_00680	3.906e-20	91.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
GZD2_k127_1704244_1	926569.ANT_00690	3.428e-118	392.0	COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase 28 domain	-	-	2.4.1.46	ko:K03715	ko00561,ko01100,map00561,map01100	-	R02691	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
GZD2_k127_1704244_11	502025.Hoch_3168	1.535e-38	154.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,43CNJ@68525|delta/epsilon subdivisions,2X7VW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
GZD2_k127_1704244_7	926569.ANT_31670	1.869e-54	199.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GZD2_k127_1704244_4	926569.ANT_31660	3.367e-69	241.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GZD2_k127_1704244_9	926569.ANT_31650	2.692e-43	162.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GZD2_k127_1704244_5	309801.trd_0206	3.921e-69	239.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,27XM8@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GZD2_k127_1704244_0	926569.ANT_31630	1.738e-145	467.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GZD2_k127_1704244_8	926569.ANT_31630	5.626e-45	166.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GZD2_k127_1704244_15	161156.JQKW01000007_gene855	6.743e-13	69.0	COG0451@1|root,COG0451@2|Bacteria,2GHRK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
GZD2_k127_1704638_4	375286.mma_2824	2.77e-51	206.0	COG4932@1|root,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria,2WHMC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
GZD2_k127_1704638_6	926569.ANT_08030	2.639e-36	158.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GZD2_k127_1704638_2	317936.Nos7107_0099	1.654e-145	513.0	COG1361@1|root,COG2885@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,1G6ER@1117|Cyanobacteria,1HQ0Q@1161|Nostocales	1117|Cyanobacteria	M	Conserved repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GZD2_k127_1704638_5	1121897.AUGO01000001_gene1121	6.612e-40	173.0	COG1470@1|root,COG1520@1|root,COG1572@1|root,COG3291@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NURE@237|Flavobacterium	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,DUF11,Ig_3,P_proprotein,SBBP
GZD2_k127_1704638_7	1437600.JDUI01000003_gene80	1.256e-05	60.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
GZD2_k127_1704638_0	926550.CLDAP_19050	2.096e-186	591.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD2_k127_1704638_3	926569.ANT_13270	8.506e-93	315.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_1704638_1	926569.ANT_13260	6.831e-152	492.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GZD2_k127_171364_4	926569.ANT_24780	1.65e-23	102.0	COG0437@1|root,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
GZD2_k127_171364_0	926569.ANT_24770	4.375e-184	586.0	COG5557@1|root,COG5557@2|Bacteria,2G68D@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
GZD2_k127_171364_3	926569.ANT_24760	1.258e-32	133.0	2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GZD2_k127_171364_2	926569.ANT_24750	1.415e-44	168.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GZD2_k127_171364_5	421072.IO89_01820	1.642e-08	64.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,3HGP7@358033|Chryseobacterium	976|Bacteroidetes	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
GZD2_k127_171364_1	204773.HEAR0704	1.252e-47	177.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR8T@28216|Betaproteobacteria,473F8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
GZD2_k127_1717887_2	485913.Krac_11842	1.935e-205	655.0	28JU5@1|root,2Z9J8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_1717887_4	1380346.JNIH01000080_gene2606	6.898e-80	276.0	2CHZY@1|root,32YTS@2|Bacteria,2ISB0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1717887_8	765420.OSCT_1771	2.152e-07	61.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
GZD2_k127_1717887_3	1262449.CP6013_2264	9.413e-102	350.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,248FU@186801|Clostridia,36EP3@31979|Clostridiaceae	186801|Clostridia	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
GZD2_k127_1717887_9	1242864.D187_007312	8.206e-07	62.0	COG1672@1|root,COG1672@2|Bacteria,1R2HA@1224|Proteobacteria,430VH@68525|delta/epsilon subdivisions,2WVMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1717887_0	478741.JAFS01000002_gene870	7.433e-224	724.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,37FUH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
GZD2_k127_1717887_7	926569.ANT_22100	9.019e-24	107.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD2_k127_1717887_6	926569.ANT_22090	2.332e-25	110.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
GZD2_k127_1717887_1	926569.ANT_22080	8.503e-221	700.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	926569.ANT_22080|-	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1717887_5	926569.ANT_22070	6.148e-72	252.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	1.6.5.3	ko:K00342,ko:K00343,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GZD2_k127_1724110_4	218284.CCDN010000001_gene1842	1.6e-73	259.0	2CUQ5@1|root,32SVT@2|Bacteria,1VW80@1239|Firmicutes,4HW7I@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1724110_6	946235.CAER01000051_gene1574	5.151e-14	81.0	COG0563@1|root,COG0563@2|Bacteria,1V1QU@1239|Firmicutes,4HGI2@91061|Bacilli,23M0A@182709|Oceanobacillus	91061|Bacilli	F	COG0563 Adenylate kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,SKI
GZD2_k127_1724110_2	649638.Trad_0522	1.336e-85	299.0	COG2244@1|root,COG2244@2|Bacteria,1WN8J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1724110_7	370438.PTH_0376	2.614e-10	70.0	COG4743@1|root,COG4743@2|Bacteria,1TSEB@1239|Firmicutes,24DEA@186801|Clostridia,2618T@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
GZD2_k127_1724110_3	1134912.AJTV01000042_gene3588	6.226e-78	287.0	COG1807@1|root,COG1807@2|Bacteria,1R71E@1224|Proteobacteria,2TVCJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1724110_0	172088.AUGA01000083_gene4385	3.287e-122	405.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U269@28211|Alphaproteobacteria,3JU3T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_1724110_1	460265.Mnod_6871	1.612e-113	380.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1RFXH@1224|Proteobacteria,2U8WU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_1724110_5	469371.Tbis_2675	4.797e-24	105.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,4E3A1@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_17303_0	357808.RoseRS_2972	3.389e-113	378.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD2_k127_17303_1	316274.Haur_3168	4.881e-63	231.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_17303_2	243230.DR_2376	2.532e-32	131.0	COG1309@1|root,COG1309@2|Bacteria,1WI7P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
GZD2_k127_173674_3	1123368.AUIS01000001_gene1869	2.238e-55	201.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,2NCJN@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_173674_0	118161.KB235922_gene5010	4.824e-107	361.0	COG5621@1|root,COG5621@2|Bacteria,1G3K9@1117|Cyanobacteria	1117|Cyanobacteria	H	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9,polyprenyl_synt
GZD2_k127_173674_2	1123368.AUIS01000015_gene2638	1.809e-61	219.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S2XY@1236|Gammaproteobacteria,2NC17@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_173674_1	111781.Lepto7376_4064	1.725e-82	286.0	COG0577@1|root,COG0577@2|Bacteria,1G04T@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_1736994_1	272123.Anacy_3024	7.277e-77	272.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
GZD2_k127_1736994_0	926550.CLDAP_36180	2.468e-155	497.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
GZD2_k127_1736994_2	926550.CLDAP_36170	7.499e-34	132.0	COG1232@1|root,COG1232@2|Bacteria,2G83R@200795|Chloroflexi	200795|Chloroflexi	H	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD2_k127_1737631_0	1128421.JAGA01000004_gene2674	1.124e-234	737.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
GZD2_k127_1737631_1	118168.MC7420_8015	4.484e-86	300.0	COG0395@1|root,COG0395@2|Bacteria,1G2TR@1117|Cyanobacteria,1H9ME@1150|Oscillatoriales	1117|Cyanobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GZD2_k127_1737631_2	1382306.JNIM01000001_gene1416	7.378e-78	269.0	COG1175@1|root,COG1175@2|Bacteria,2G7P7@200795|Chloroflexi	200795|Chloroflexi	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GZD2_k127_1739724_3	309801.trd_A0702	4.822e-58	208.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
GZD2_k127_1739724_2	926569.ANT_16620	2.94e-69	243.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
GZD2_k127_1739724_1	926550.CLDAP_35880	7.417e-106	355.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
GZD2_k127_1739724_4	292459.STH169	1.858e-30	128.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_1739724_0	926569.ANT_12980	2.945e-303	970.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
GZD2_k127_174021_2	926560.KE387027_gene366	4.156e-112	375.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GZD2_k127_174021_6	867845.KI911784_gene2206	1.517e-08	65.0	COG1716@1|root,COG3391@1|root,COG4733@1|root,COG1716@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1,3.2.1.78	ko:K01218,ko:K12132	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26	-	FHA,NHL,PA14,fn3
GZD2_k127_174021_0	926569.ANT_15490	3.354e-287	892.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GZD2_k127_174021_4	1499967.BAYZ01000026_gene1594	1.533e-44	173.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_174021_1	485913.Krac_11734	1.924e-140	465.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GZD2_k127_174021_3	926569.ANT_17240	2.276e-89	308.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
GZD2_k127_174021_5	1480694.DC28_13515	6.486e-34	144.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.99.1.3	ko:K02470,ko:K03833	-	-	-	-	ko00000,ko01000,ko03012,ko03032,ko03400	-	-	-	HATPase_c,HTH_20
GZD2_k127_1747485_4	1267534.KB906754_gene3893	0.0004362	43.0	COG2010@1|root,COG2010@2|Bacteria,3Y3HF@57723|Acidobacteria,2JIYR@204432|Acidobacteriia	204432|Acidobacteriia	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
GZD2_k127_1747485_1	1128421.JAGA01000003_gene2871	4.091e-194	614.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
GZD2_k127_1747485_0	472759.Nhal_2603	0.0	1036.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
GZD2_k127_1747485_2	886293.Sinac_3667	1.958e-82	279.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GZD2_k127_1747485_3	1448139.AI20_06860	8.694e-09	59.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1Y5CW@135624|Aeromonadales	135624|Aeromonadales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GZD2_k127_1750897_4	1121920.AUAU01000012_gene2648	5.507e-35	139.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
GZD2_k127_1750897_2	523841.HFX_2210	1.067e-59	217.0	COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,23TXG@183963|Halobacteria	183963|Halobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	hmoA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11
GZD2_k127_1750897_6	443144.GM21_3544	6.58e-11	73.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Multi-haem_cyto,Paired_CXXCH_1
GZD2_k127_1750897_0	926569.ANT_21930	2.651e-255	809.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
GZD2_k127_1750897_1	485913.Krac_6669	8.844e-63	225.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_1750897_3	525904.Tter_0301	7.7e-40	166.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
GZD2_k127_1750897_5	926569.ANT_26960	1.381e-30	131.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1764219_5	926569.ANT_21020	1.117e-49	186.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_1764219_1	1236541.BALL01000001_gene137	7.958e-93	317.0	COG4104@1|root,COG4104@2|Bacteria,1QPK2@1224|Proteobacteria,1RS4X@1236|Gammaproteobacteria,2QB84@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Lysine-specific metallo-endopeptidase	-	-	3.4.24.20	ko:K08646	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Aspzincin_M35
GZD2_k127_1764219_3	926569.ANT_07860	2.847e-75	262.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_1764219_6	489825.LYNGBM3L_66970	7.934e-13	72.0	2E4G4@1|root,32ZB9@2|Bacteria,1G9UK@1117|Cyanobacteria,1HD1D@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1764219_7	864702.OsccyDRAFT_2951	1.795e-10	66.0	2E4G4@1|root,32ZB9@2|Bacteria,1G9UK@1117|Cyanobacteria,1HD1D@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1764219_2	1382356.JQMP01000003_gene1717	5.379e-89	300.0	COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi,27Y8G@189775|Thermomicrobia	189775|Thermomicrobia	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GZD2_k127_1764219_4	926569.ANT_21000	2.565e-55	196.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GZD2_k127_1764219_0	926569.ANT_11400	7.21e-180	583.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
GZD2_k127_1764406_4	1521187.JPIM01000044_gene3305	6.101e-55	196.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi,375FT@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GZD2_k127_1764406_2	408672.NBCG_01914	1.312e-65	248.0	COG4249@1|root,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria,4DT2Z@85009|Propionibacteriales	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
GZD2_k127_1764406_7	1463903.JOIZ01000003_gene1662	4.318e-10	65.0	2B5YA@1|root,31YUA@2|Bacteria,2IJSR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1764406_3	1382304.JNIL01000001_gene1817	2.463e-57	209.0	COG3885@1|root,COG3885@2|Bacteria,1TUKQ@1239|Firmicutes,4HJ5V@91061|Bacilli	91061|Bacilli	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
GZD2_k127_1764406_5	439235.Dalk_1417	1.2e-39	150.0	COG1586@1|root,COG1586@2|Bacteria,1REQP@1224|Proteobacteria,42RVE@68525|delta/epsilon subdivisions,2WNJ5@28221|Deltaproteobacteria,2MJVH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	S-adenosylmethionine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	AdoMet_dc
GZD2_k127_1764406_0	391625.PPSIR1_16360	1.207e-84	291.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
GZD2_k127_1764406_1	1120949.KB903311_gene777	6.404e-69	242.0	2DBF0@1|root,2Z8VT@2|Bacteria,2I88D@201174|Actinobacteria,4DIBF@85008|Micromonosporales	201174|Actinobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
GZD2_k127_176546_2	497964.CfE428DRAFT_3775	1.094e-17	83.0	COG0446@1|root,COG0446@2|Bacteria,46SG9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
GZD2_k127_176546_4	1380390.JIAT01000011_gene2402	6.997e-05	49.0	COG1917@1|root,COG1917@2|Bacteria,2HN4T@201174|Actinobacteria,4CQJ2@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_176546_0	1005048.CFU_2318	4.373e-101	336.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
GZD2_k127_176546_1	1382306.JNIM01000001_gene542	2.559e-91	309.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GZD2_k127_176546_3	877455.Metbo_1657	1.215e-06	57.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GZD2_k127_1768875_2	321327.CYA_2877	2.781e-09	68.0	COG2866@1|root,COG2866@2|Bacteria,1GPAI@1117|Cyanobacteria,1H2Q7@1129|Synechococcus	1117|Cyanobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GZD2_k127_1768875_1	316274.Haur_2664	1.765e-27	124.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GZD2_k127_1768875_0	926569.ANT_21050	8.926e-307	952.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
GZD2_k127_177634_1	926569.ANT_13180	4.689e-143	464.0	COG1055@1|root,COG1055@2|Bacteria,2G67U@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Arsenical pump membrane protein	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	CitMHS
GZD2_k127_177634_0	1121468.AUBR01000034_gene1377	5.83e-315	975.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales	1239|Firmicutes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD2_k127_177634_3	1151122.AQYD01000007_gene24	5.942e-28	122.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FS38@85023|Microbacteriaceae	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_177634_4	1521187.JPIM01000022_gene618	6.597e-08	63.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD2_k127_177634_2	357808.RoseRS_3083	1.238e-38	146.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GZD2_k127_1786580_1	926569.ANT_29640	2.216e-108	359.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GZD2_k127_1786580_3	1502724.FF80_01574	1.955e-52	189.0	COG0645@1|root,COG0645@2|Bacteria,1Q3U4@1224|Proteobacteria,2UIA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GZD2_k127_1786580_2	1120950.KB892752_gene6138	2.276e-68	237.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4DQP6@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_1786580_0	926569.ANT_29800	4.7e-213	670.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GZD2_k127_1786580_5	1462527.CCDM010000002_gene890	1.123e-40	155.0	COG0494@1|root,COG0494@2|Bacteria,1VPHI@1239|Firmicutes,4HR9R@91061|Bacilli	91061|Bacilli	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_1786580_4	1370121.AUWS01000030_gene2862	4.399e-41	159.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,23F1N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GZD2_k127_1786580_6	1082931.KKY_794	3.306e-23	104.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UCNU@28211|Alphaproteobacteria,3N7FR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GZD2_k127_1789772_0	1121324.CLIT_8c01210	2.212e-174	565.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GZD2_k127_1789772_1	357808.RoseRS_3926	7.255e-156	503.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD2_k127_1789772_2	526227.Mesil_2410	3.006e-76	259.0	COG0001@1|root,COG0001@2|Bacteria,1WM90@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD2_k127_1792812_2	765420.OSCT_1131	2.778e-93	314.0	COG0382@1|root,COG0382@2|Bacteria,2GA35@200795|Chloroflexi,376IW@32061|Chloroflexia	32061|Chloroflexia	H	UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
GZD2_k127_1792812_1	926569.ANT_05100	4.505e-113	371.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
GZD2_k127_1792812_4	1285586.H131_11898	2.797e-36	148.0	COG3393@1|root,COG3393@2|Bacteria,1UG1Z@1239|Firmicutes,4HCEK@91061|Bacilli,3IXRH@400634|Lysinibacillus	91061|Bacilli	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1792812_3	358681.BBR47_17010	2.357e-58	215.0	COG3153@1|root,COG3153@2|Bacteria,1UYNZ@1239|Firmicutes,4HD7N@91061|Bacilli,2718M@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_1792812_0	926569.ANT_22700	5.549e-240	755.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_1799723_0	525904.Tter_2276	1.402e-84	296.0	COG1721@1|root,COG1721@2|Bacteria,2NR5R@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GZD2_k127_1799723_1	525904.Tter_2275	2.353e-38	146.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GZD2_k127_1812020_6	1128421.JAGA01000002_gene522	8.459e-29	116.0	COG2148@1|root,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GZD2_k127_1812020_0	316274.Haur_3576	7.772e-122	404.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_1812020_4	316274.Haur_3578	9.689e-71	252.0	COG2199@1|root,COG3944@1|root,COG2199@2|Bacteria,COG3944@2|Bacteria,2GBA7@200795|Chloroflexi,377N2@32061|Chloroflexia	32061|Chloroflexia	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
GZD2_k127_1812020_5	383372.Rcas_3110	9.658e-62	222.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
GZD2_k127_1812020_2	316274.Haur_3579	2.977e-88	310.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD2_k127_1812020_1	357808.RoseRS_2377	2.304e-115	389.0	COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia	32061|Chloroflexia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
GZD2_k127_1812020_3	383372.Rcas_3100	3.842e-77	269.0	COG1216@1|root,COG1216@2|Bacteria,2G76E@200795|Chloroflexi,377ZP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_1812191_2	926569.ANT_11090	1.705e-85	294.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_1812191_7	700598.Niako_0542	1.675e-20	94.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD2_k127_1812191_9	1286093.C266_20724	2.679e-18	87.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,2VX6M@28216|Betaproteobacteria,1KA9D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cation transport regulator	-	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
GZD2_k127_1812191_8	1123261.AXDW01000013_gene3529	9.603e-19	87.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1X8CX@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GZD2_k127_1812191_1	926569.ANT_19900	3.306e-138	450.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_1812191_4	316274.Haur_1219	2.49e-41	155.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GZD2_k127_1812191_6	316274.Haur_1219	1.447e-28	119.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GZD2_k127_1812191_0	316274.Haur_1218	8.938e-211	668.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
GZD2_k127_1812191_3	316274.Haur_1217	3.674e-80	291.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_1812191_5	316274.Haur_1217	9.359e-40	166.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_1814339_2	326427.Cagg_0341	5.76e-13	78.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD2_k127_1814339_1	316274.Haur_1105	1.858e-31	138.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
GZD2_k127_1814339_0	867845.KI911784_gene2163	1.267e-67	237.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_1841870_5	1108045.GORHZ_172_00050	8.96e-21	94.0	2E3U2@1|root,31XU0@2|Bacteria,2HZEP@201174|Actinobacteria,4GGN4@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1841870_6	319003.Bra1253DRAFT_00172	1.928e-19	91.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria,3K512@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1841870_2	765420.OSCT_1055	6.545e-234	759.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi,375BC@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_8
GZD2_k127_1841870_0	706587.Desti_2109	0.0	1130.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GZD2_k127_1841870_1	1123368.AUIS01000001_gene1961	3.235e-253	801.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,1RYY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD2_k127_1841870_3	1267535.KB906767_gene67	9.719e-116	389.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria,2JIT3@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
GZD2_k127_1841870_4	1499686.BN1079_01107	7.77e-38	143.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GZD2_k127_1841870_7	706587.Desti_4754	7.895e-19	88.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42SDZ@68525|delta/epsilon subdivisions,2WPXS@28221|Deltaproteobacteria,2MSFK@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ-2	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD2_k127_1851386_1	697284.ERIC2_c09080	1.724e-42	162.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,4HFXH@91061|Bacilli,26S9D@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_1851386_0	697284.ERIC2_c09070	3.356e-62	223.0	COG4587@1|root,COG4587@2|Bacteria,1UZ3Y@1239|Firmicutes,4HFHM@91061|Bacilli,26V8Z@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_1851386_2	1197130.BAFM01000015_gene2443	3.66e-40	156.0	arCOG01782@1|root,arCOG01782@2157|Archaea,2XTX4@28890|Euryarchaeota,23TWF@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_1851386_3	485913.Krac_5382	5.008e-34	138.0	2DM3D@1|root,31J5I@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
GZD2_k127_1853861_1	926569.ANT_12970	7.666e-66	228.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GZD2_k127_1853861_2	207559.Dde_3087	4.386e-40	161.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42PHT@68525|delta/epsilon subdivisions,2WKTH@28221|Deltaproteobacteria,2MCXW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD2_k127_1853861_0	1173022.Cri9333_3799	1.091e-114	377.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1H7Y9@1150|Oscillatoriales	1117|Cyanobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
GZD2_k127_1853861_3	1157490.EL26_06220	1.745e-39	153.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,2787M@186823|Alicyclobacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
GZD2_k127_1855110_5	926569.ANT_18940	4.693e-10	61.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi	200795|Chloroflexi	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
GZD2_k127_1855110_0	886293.Sinac_6174	2.064e-89	305.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GZD2_k127_1855110_1	926569.ANT_06720	1.143e-35	139.0	COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
GZD2_k127_1855110_2	926569.ANT_10390	1.096e-25	119.0	COG3595@1|root,COG3595@2|Bacteria,2G7DM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GZD2_k127_1855110_3	926569.ANT_06730	6.734e-25	107.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1865027_4	661478.OP10G_0003	3.015e-28	124.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
GZD2_k127_1865027_2	485913.Krac_10314	9.413e-58	213.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
GZD2_k127_1865027_3	1254432.SCE1572_02625	1.733e-44	164.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1N3KK@1224|Proteobacteria,42TH7@68525|delta/epsilon subdivisions,2WQ6A@28221|Deltaproteobacteria,2YVVZ@29|Myxococcales	28221|Deltaproteobacteria	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20
GZD2_k127_1865027_1	1265505.ATUG01000001_gene4318	1.189e-129	429.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GZD2_k127_1865027_0	926550.CLDAP_05160	5.2e-131	436.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_1880141_0	1121346.KB899810_gene1349	4.469e-127	419.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,26RHU@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M29	ampS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GZD2_k127_1880141_1	926554.KI912628_gene2716	9.198e-27	112.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GZD2_k127_1884205_0	1121468.AUBR01000003_gene633	4.434e-162	524.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
GZD2_k127_1884205_3	926569.ANT_11330	3.528e-55	198.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GZD2_k127_1884205_2	926569.ANT_15100	4.162e-59	206.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD2_k127_1884205_1	1125863.JAFN01000001_gene765	4.979e-65	229.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GZD2_k127_1884485_4	926569.ANT_28800	3.389e-30	123.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD2_k127_1884485_2	383372.Rcas_1231	6.735e-155	494.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi,376UE@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
GZD2_k127_1884485_1	926569.ANT_28810	2.696e-174	552.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
GZD2_k127_1884485_5	96561.Dole_1022	2.558e-24	119.0	2DSRT@1|root,33H76@2|Bacteria,1NY5C@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1884485_0	926569.ANT_28820	3.16e-188	597.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
GZD2_k127_1884485_3	926569.ANT_24720	9.084e-57	204.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD2_k127_1886793_1	926569.ANT_07340	2.522e-134	432.0	COG0474@1|root,COG0474@2|Bacteria,2G60Z@200795|Chloroflexi	200795|Chloroflexi	P	Cation transporting ATPase, C-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD2_k127_1886793_2	324602.Caur_0607	7.82e-122	413.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
GZD2_k127_1886793_0	234267.Acid_2679	2.325e-238	758.0	COG1472@1|root,COG1472@2|Bacteria,3Y3QE@57723|Acidobacteria	57723|Acidobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GZD2_k127_1886820_7	306281.AJLK01000072_gene656	7.653e-06	50.0	COG3315@1|root,COG3315@2|Bacteria,1G5YU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
GZD2_k127_1886820_4	1195236.CTER_5173	1.76e-39	151.0	2F4ZG@1|root,33XM8@2|Bacteria,1VWEB@1239|Firmicutes,24TCJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1886820_5	1128421.JAGA01000003_gene2882	1.041e-36	144.0	COG3685@1|root,COG3685@2|Bacteria	2|Bacteria	S	cellular response to DNA damage stimulus	yciE	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	DUF892
GZD2_k127_1886820_3	926569.ANT_19290	2.399e-56	206.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1886820_2	926569.ANT_19280	1.774e-95	318.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
GZD2_k127_1886820_0	926569.ANT_13240	4.991e-158	507.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
GZD2_k127_1886820_1	555079.Toce_1855	2.287e-124	409.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GZD2_k127_1891731_0	1163409.UUA_08356	3.367e-113	374.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,1X5T4@135614|Xanthomonadales	135614|Xanthomonadales	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GZD2_k127_1891731_1	945713.IALB_2065	3.246e-59	217.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK
GZD2_k127_189931_0	926550.CLDAP_30470	0.0	1153.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_189931_1	926550.CLDAP_30480	3.676e-96	324.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
GZD2_k127_1909463_2	443255.SCLAV_1171	1.691e-12	73.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_1909463_1	378806.STAUR_1465	4.501e-44	171.0	COG0454@1|root,COG0456@2|Bacteria,1R7PK@1224|Proteobacteria	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GZD2_k127_1909463_0	309799.DICTH_1642	3.744e-53	204.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02103,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
GZD2_k127_1913197_1	926569.ANT_04250	2.188e-245	768.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
GZD2_k127_1913197_9	543728.Vapar_1658	6.469e-15	79.0	COG0642@1|root,COG2199@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_1913197_6	926569.ANT_04290	6.673e-30	124.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
GZD2_k127_1913197_3	926569.ANT_04260	8.383e-67	230.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GZD2_k127_1913197_2	926569.ANT_05310	9.171e-96	323.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GZD2_k127_1913197_0	926569.ANT_05300	4.643e-263	829.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD2_k127_1913197_4	926569.ANT_05280	2.422e-59	215.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GZD2_k127_1913197_5	926569.ANT_05250	6.638e-43	166.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
GZD2_k127_1913197_8	926569.ANT_05240	1.323e-16	86.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GZD2_k127_1915871_2	861208.AGROH133_15140	9.719e-23	100.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2V825@28211|Alphaproteobacteria,4BG91@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GZD2_k127_1915871_0	1349767.GJA_1885	4.423e-164	520.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VZC2@28216|Betaproteobacteria,472SP@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_1915871_1	1101188.KI912155_gene1728	8.514e-146	468.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,1W7G0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GZD2_k127_1915871_3	926569.ANT_30570	1.338e-13	74.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
GZD2_k127_1924288_1	926569.ANT_10850	1.191e-102	341.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
GZD2_k127_1924288_0	671143.DAMO_0407	5.902e-242	765.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_1924288_2	926569.ANT_22970	2.004e-20	93.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_1928998_1	926569.ANT_25030	3.792e-104	346.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GZD2_k127_1928998_6	316274.Haur_0149	5.586e-19	92.0	COG1051@1|root,COG1051@2|Bacteria,2G9MA@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_1928998_3	671143.DAMO_2925	5.611e-42	158.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
GZD2_k127_1928998_4	671143.DAMO_2926	3.009e-35	139.0	COG0239@1|root,COG0239@2|Bacteria,2NQ56@2323|unclassified Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GZD2_k127_1928998_2	243233.MCA1900	4.698e-104	347.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XF2R@135618|Methylococcales	135618|Methylococcales	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GZD2_k127_1928998_5	926569.ANT_07520	1.384e-25	108.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD2_k127_1928998_0	926569.ANT_25040	2.323e-112	368.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
GZD2_k127_1932258_0	1131730.BAVI_16847	3.662e-187	600.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,1ZQWV@1386|Bacillus	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GZD2_k127_1932258_2	937777.Deipe_0063	7.255e-100	336.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GZD2_k127_1932258_1	937777.Deipe_0063	4.541e-106	349.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GZD2_k127_1937157_3	1210884.HG799465_gene11440	4.443e-34	136.0	28WG9@1|root,2ZIGE@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD2_k127_1937157_1	357808.RoseRS_3183	2.093e-115	386.0	COG1721@1|root,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GZD2_k127_1937157_0	383372.Rcas_2912	1.512e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GZD2_k127_1937157_5	383372.Rcas_2914	1.002e-15	87.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
GZD2_k127_1937157_4	926569.ANT_17270	2.059e-30	130.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
GZD2_k127_1937157_7	1173029.JH980292_gene3926	8.92e-05	53.0	COG0515@1|root,COG0515@2|Bacteria,1G8NX@1117|Cyanobacteria,1HCBP@1150|Oscillatoriales	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1937157_2	313612.L8106_13405	1.525e-62	222.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GZD2_k127_1937157_6	926569.ANT_17290	9.652e-13	72.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GZD2_k127_19384_0	926569.ANT_05610	8.171e-179	569.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
GZD2_k127_19384_1	1196323.ALKF01000178_gene247	3.18e-68	243.0	COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,274KT@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	lacC	-	2.7.1.144	ko:K00917	ko00052,ko01100,map00052,map01100	-	R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GZD2_k127_1946710_0	290397.Adeh_2304	1.531e-128	416.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_1946710_2	926550.CLDAP_27480	1.957e-34	145.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GZD2_k127_1946710_1	1158292.JPOE01000002_gene1687	3.221e-104	347.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,1KKM1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_1946710_3	706587.Desti_5234	9.76e-08	57.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	ybhF-N	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_1953348_5	316274.Haur_2117	3.423e-14	73.0	COG1172@1|root,COG1172@2|Bacteria,2G8WV@200795|Chloroflexi,377N4@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GZD2_k127_1953348_1	316274.Haur_2118	1.514e-161	516.0	COG1172@1|root,COG1172@2|Bacteria,2G6A4@200795|Chloroflexi,377ZT@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GZD2_k127_1953348_0	316274.Haur_2119	1.868e-234	734.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GZD2_k127_1953348_2	316274.Haur_2120	8.266e-158	503.0	COG1879@1|root,COG1879@2|Bacteria,2GB9Z@200795|Chloroflexi,377MV@32061|Chloroflexia	32061|Chloroflexia	G	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GZD2_k127_1953348_3	926550.CLDAP_27330	1.188e-98	332.0	COG1609@1|root,COG1609@2|Bacteria,2G6BD@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
GZD2_k127_1953348_4	448385.sce2224	1.667e-53	189.0	COG0451@1|root,COG0451@2|Bacteria,1R456@1224|Proteobacteria	1224|Proteobacteria	GM	udp-glucose 4-epimerase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GZD2_k127_1954736_1	240015.ACP_0460	3.533e-174	564.0	COG0038@1|root,COG0038@2|Bacteria,3Y7TT@57723|Acidobacteria,2JMYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
GZD2_k127_1954736_0	247490.KSU1_C0490	9.326e-183	592.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2IY1G@203682|Planctomycetes	203682|Planctomycetes	P	COG0038 Chloride channel protein EriC	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
GZD2_k127_1965894_1	419947.MRA_3418	5.955e-65	235.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
GZD2_k127_1965894_0	419947.MRA_3417	8.052e-129	428.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
GZD2_k127_1965894_2	1249627.D779_1003	9.737e-53	207.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07677	ko02020,ko02026,map02020,map02026	M00474	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,TarH
GZD2_k127_1965894_3	13690.CP98_04487	6.271e-10	65.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2K53C@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
GZD2_k127_1968827_0	1005048.CFU_3993	9.82e-104	356.0	COG0318@1|root,COG2267@1|root,COG0318@2|Bacteria,COG2267@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GZD2_k127_1968827_1	926550.CLDAP_01280	3.124e-86	300.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_197438_0	1128421.JAGA01000002_gene971	2.024e-117	386.0	COG2309@1|root,COG2309@2|Bacteria,2NPEI@2323|unclassified Bacteria	2|Bacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GZD2_k127_197438_1	1499967.BAYZ01000013_gene6463	8.122e-78	269.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
GZD2_k127_197438_2	243233.MCA2183	1.023e-75	256.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GZD2_k127_197438_3	388413.ALPR1_11535	6.587e-27	121.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
GZD2_k127_1980974_1	1009370.ALO_05268	7e-48	179.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GZD2_k127_1980974_5	926569.ANT_08190	8.778e-23	98.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
GZD2_k127_1980974_6	468059.AUHA01000004_gene2327	4.481e-14	75.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1IWMM@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
GZD2_k127_1980974_0	765420.OSCT_2998	1.311e-120	401.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pyr_redox_2
GZD2_k127_1980974_2	765420.OSCT_2999	1.503e-47	177.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
GZD2_k127_1980974_4	765420.OSCT_3000	1.345e-33	134.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
GZD2_k127_1980974_3	765420.OSCT_3000	4.253e-42	157.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
GZD2_k127_1995922_0	765420.OSCT_2236	4.298e-265	862.0	COG3292@1|root,COG3829@1|root,COG4585@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2G7P1@200795|Chloroflexi	200795|Chloroflexi	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
GZD2_k127_1995922_6	1521187.JPIM01000016_gene3688	1.386e-75	257.0	COG2077@1|root,COG2077@2|Bacteria,2G8IQ@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
GZD2_k127_1995922_4	357808.RoseRS_3819	2.151e-100	340.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GZD2_k127_1995922_5	1048834.TC41_2973	4.963e-77	272.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,278WV@186823|Alicyclobacillaceae	91061|Bacilli	E	PFAM aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_1995922_2	134676.ACPL_3265	3.639e-105	352.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria,4DHGU@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GZD2_k127_1995922_3	926569.ANT_03360	1.355e-102	341.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
GZD2_k127_1995922_7	1545915.JROG01000001_gene591	7.228e-61	230.0	2EB6E@1|root,33574@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1995922_9	1160137.KB907307_gene1050	9.414e-06	53.0	28WNI@1|root,2ZINA@2|Bacteria,2GWW8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_1995922_1	926569.ANT_05950	3.983e-159	518.0	COG0147@1|root,COG1169@1|root,COG0147@2|Bacteria,COG1169@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GZD2_k127_1995922_8	1476583.DEIPH_ctg029orf0037	9.04e-09	56.0	COG0180@1|root,COG0180@2|Bacteria	2|Bacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GZD2_k127_2004136_3	926569.ANT_04520	7.453e-69	237.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
GZD2_k127_2004136_0	590998.Celf_1230	3.134e-164	528.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4F14I@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Glyco_hydro_6
GZD2_k127_2004136_2	706587.Desti_5093	1.241e-89	311.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GZD2_k127_2004136_1	1267535.KB906767_gene788	7.708e-139	451.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
GZD2_k127_2004136_5	1237149.C900_00143	4.018e-52	199.0	COG0656@1|root,COG0656@2|Bacteria,4NFTA@976|Bacteroidetes,47KNY@768503|Cytophagia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06222	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
GZD2_k127_2004136_7	357808.RoseRS_2245	1.958e-20	94.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
GZD2_k127_2004136_4	383372.Rcas_4248	1.598e-52	197.0	COG0204@1|root,COG0204@2|Bacteria,2G92W@200795|Chloroflexi,3779N@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GZD2_k127_2004136_8	926550.CLDAP_07570	6.455e-15	79.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GZD2_k127_2021515_1	648885.KB316283_gene3628	2.015e-60	214.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2TU5B@28211|Alphaproteobacteria,1JS8K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
GZD2_k127_2021515_0	926569.ANT_03540	2.29e-79	267.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi	200795|Chloroflexi	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
GZD2_k127_2021515_2	889378.Spiaf_0819	2.323e-17	91.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	hoxI	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	EAL,FliG_C,HATPase_c,HisKA,cNMP_binding
GZD2_k127_2037834_6	383372.Rcas_3100	1.126e-34	139.0	COG1216@1|root,COG1216@2|Bacteria,2G76E@200795|Chloroflexi,377ZP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_2037834_3	1128421.JAGA01000002_gene526	1.182e-67	244.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_2037834_0	357808.RoseRS_2373	3.527e-126	415.0	COG1215@1|root,COG1215@2|Bacteria,2GAJA@200795|Chloroflexi,376HJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GZD2_k127_2037834_1	357808.RoseRS_3820	2.988e-112	392.0	28HGC@1|root,30IRW@2|Bacteria,2GA7N@200795|Chloroflexi,376R6@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
GZD2_k127_2037834_2	316274.Haur_3582	4.478e-96	327.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_2037834_4	1128421.JAGA01000002_gene530	3.489e-59	220.0	28J8U@1|root,33EE0@2|Bacteria	2|Bacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
GZD2_k127_2037834_5	1051501.AYTL01000033_gene235	2.02e-38	149.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
GZD2_k127_2037834_7	1183438.GKIL_2486	1.503e-18	93.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2040491_1	1254432.SCE1572_51525	8.94e-09	69.0	COG0750@1|root,COG2234@1|root,COG0750@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
GZD2_k127_2040491_0	1499689.CCNN01000007_gene865	1.263e-90	318.0	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,2495H@186801|Clostridia,36WDR@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Beta-lactamase,DUF302
GZD2_k127_2040491_2	234267.Acid_1202	1.198e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,3Y46U@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_2048374_0	926569.ANT_16070	3.037e-91	308.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
GZD2_k127_2048374_1	1238425.J07HQW2_03479	1.988e-45	177.0	COG4221@1|root,arCOG01265@2157|Archaea,2XT0E@28890|Euryarchaeota,23U0H@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_2054105_0	1128421.JAGA01000003_gene3375	1.757e-109	361.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
GZD2_k127_2057455_0	439235.Dalk_4226	4.335e-262	817.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
GZD2_k127_2057455_5	344747.PM8797T_26125	7.921e-13	79.0	COG3506@1|root,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	DUF1349,PI-PLC-C1,fn3
GZD2_k127_2057455_1	927677.ALVU02000004_gene4738	8.091e-120	425.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12
GZD2_k127_2057455_6	159087.Daro_3823	5.48e-08	64.0	2BZCH@1|root,348M0@2|Bacteria,1P0X6@1224|Proteobacteria,2W3ZH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2057455_3	635013.TherJR_1729	3.239e-57	216.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
GZD2_k127_2057455_2	639283.Snov_2165	7.813e-106	356.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,3EYKB@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
GZD2_k127_2057455_4	309801.trd_A0679	3.725e-40	165.0	COG3420@1|root,COG3420@2|Bacteria,2GBD6@200795|Chloroflexi,27YVB@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GZD2_k127_2086114_0	479434.Sthe_3176	3.784e-255	799.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GZD2_k127_2086114_2	1234364.AMSF01000064_gene2208	5.613e-124	413.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1X3E0@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
GZD2_k127_2086114_1	926569.ANT_13040	8.474e-175	558.0	COG1391@1|root,COG2844@1|root,COG1391@2|Bacteria,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89	ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020	M00017,M00018	R00243,R01773,R01775	RC00006,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	GlnD_UR_UTase,GlnE,HD
GZD2_k127_2107290_2	1173029.JH980292_gene614	1.345e-11	69.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GZD2_k127_2107290_0	913865.DOT_5581	6.91e-92	312.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,261PP@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glycyl-radical enzyme activating protein family	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
GZD2_k127_2107290_1	646529.Desaci_1175	2.474e-85	288.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
GZD2_k127_211030_7	1027273.GZ77_04390	4.961e-12	69.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XHPN@135619|Oceanospirillales	135619|Oceanospirillales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GZD2_k127_211030_6	3218.PP1S80_148V6.1	2.214e-14	87.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota,37HVT@33090|Viridiplantae,3GCJ1@35493|Streptophyta	35493|Streptophyta	V	ubiquitin binding	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
GZD2_k127_211030_5	511051.CSE_06630	7.286e-15	89.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF4091,DUF4114,PPC,Peptidase_C2,SASA
GZD2_k127_211030_1	926569.ANT_22190	1.572e-81	297.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_211030_0	1122182.KB903836_gene5006	5.531e-89	299.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria	201174|Actinobacteria	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_211030_3	1123320.KB889562_gene6565	3.009e-48	185.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GZD2_k127_211030_2	1123320.KB889562_gene6565	2.498e-48	189.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GZD2_k127_211030_4	926569.ANT_29500	7.645e-32	129.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_2139540_0	926569.ANT_14030	1.288e-294	918.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GZD2_k127_2139540_7	700598.Niako_3441	1.252e-08	59.0	COG1977@1|root,COG1977@2|Bacteria,4NVP9@976|Bacteroidetes	976|Bacteroidetes	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
GZD2_k127_2139540_1	1303518.CCALI_00534	7.194e-109	362.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_2139540_4	1121904.ARBP01000019_gene2811	1.449e-30	125.0	COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,47RVG@768503|Cytophagia	976|Bacteroidetes	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GZD2_k127_2139540_3	926569.ANT_22750	2.51e-46	173.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
GZD2_k127_2139540_6	926569.ANT_22740	2.084e-25	114.0	COG0526@1|root,COG0526@2|Bacteria,2G7HX@200795|Chloroflexi	200795|Chloroflexi	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD2_k127_2139540_5	545695.TREAZ_1612	4.641e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,2JATZ@203691|Spirochaetes	203691|Spirochaetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
GZD2_k127_2139540_2	232348.ADXL01000084_gene823	2.992e-57	203.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1G0FS@1117|Cyanobacteria,1GYMY@1129|Synechococcus	1117|Cyanobacteria	HP	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
GZD2_k127_2145767_4	1051501.AYTL01000029_gene1578	1.535e-09	68.0	COG0842@1|root,COG0842@2|Bacteria,1V7HN@1239|Firmicutes,4HGE5@91061|Bacilli,1ZCVY@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_2145767_2	316274.Haur_1889	3.264e-33	143.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_2145767_0	679926.Mpet_0474	4.316e-100	332.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_2145767_3	290399.Arth_3458	9.492e-13	79.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2145767_5	926550.CLDAP_06730	9.605e-07	60.0	2E64T@1|root,330TJ@2|Bacteria,2G93I@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2145767_1	1321778.HMPREF1982_02737	1.601e-63	229.0	COG0703@1|root,COG0703@2|Bacteria,1UMGK@1239|Firmicutes,24MFB@186801|Clostridia,26CAZ@186813|unclassified Clostridiales	186801|Clostridia	E	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_216660_5	926569.ANT_05520	5.028e-73	252.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GZD2_k127_216660_0	926569.ANT_23160	6.906e-188	616.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
GZD2_k127_216660_4	485913.Krac_2500	4.058e-76	269.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
GZD2_k127_216660_8	926569.ANT_29050	8.018e-42	159.0	COG3005@1|root,COG3005@2|Bacteria,2G748@200795|Chloroflexi	200795|Chloroflexi	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
GZD2_k127_216660_1	926569.ANT_29060	2.418e-176	563.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
GZD2_k127_216660_11	377629.TERTU_0630	1.298e-19	96.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,2PPQT@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_216660_9	671143.DAMO_1690	2.448e-32	134.0	COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_216660_6	926569.ANT_01450	2.775e-70	242.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
GZD2_k127_216660_12	468556.AQYG01000030_gene2780	0.0009736	50.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_216660_2	1430331.EP10_01290	1.936e-167	555.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1WEMW@129337|Geobacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GZD2_k127_216660_10	331678.Cphamn1_0070	6.469e-30	125.0	2C8DW@1|root,32RKY@2|Bacteria,1FF7P@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
GZD2_k127_216660_3	926569.ANT_07440	5.478e-86	293.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
GZD2_k127_216660_7	926569.ANT_29480	6.63e-56	200.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_2185395_12	410358.Mlab_1692	1.565e-13	72.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
GZD2_k127_2185395_14	588596.U9TC48	5.531e-12	71.0	COG0251@1|root,KOG2317@2759|Eukaryota,3A5RT@33154|Opisthokonta,3P5AT@4751|Fungi	4751|Fungi	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GZD2_k127_2185395_2	1033810.HLPCO_002600	1.941e-98	334.0	COG1028@1|root,COG1028@2|Bacteria	1033810.HLPCO_002600|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2185395_7	316274.Haur_2801	1.246e-51	198.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD2_k127_2185395_5	1128421.JAGA01000002_gene1281	3.441e-74	265.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD2_k127_2185395_15	926569.ANT_03880	1.312e-08	62.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GZD2_k127_2185395_3	1173020.Cha6605_1138	6.541e-89	302.0	arCOG06802@1|root,2ZBBG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2185395_4	684949.ATTJ01000002_gene334	7.08e-78	269.0	2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2185395_11	1499967.BAYZ01000019_gene6321	4.887e-27	113.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	MIase
GZD2_k127_2185395_6	509191.AEDB02000016_gene22	1.062e-51	194.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyTransf_Reg,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GZD2_k127_2185395_9	1033810.HLPCO_001863	8.297e-34	140.0	2EHEG@1|root,33B6E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD2_k127_2185395_16	1226325.HMPREF1548_01355	1.332e-06	60.0	2F8I8@1|root,340X1@2|Bacteria,1VYD1@1239|Firmicutes,24SXY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2185395_13	203124.Tery_2061	2.24e-12	75.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,FGE-sulfatase,Peptidase_C14
GZD2_k127_2185395_8	1227739.Hsw_2073	9.223e-46	169.0	COG4783@1|root,COG4783@2|Bacteria,4NEF9@976|Bacteroidetes,47XXI@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
GZD2_k127_2185395_10	484770.UFO1_1184	3.183e-27	124.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,1UZZ7@1239|Firmicutes,4H3PK@909932|Negativicutes	909932|Negativicutes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GZD2_k127_2185395_1	357808.RoseRS_3212	2.062e-119	394.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GZD2_k127_2185395_0	484770.UFO1_1183	4.375e-145	488.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_2205189_0	558884.JRGM01000141_gene1800	3.021e-77	268.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1Y4JE@135624|Aeromonadales	135624|Aeromonadales	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
GZD2_k127_2205189_1	65393.PCC7424_0297	7.127e-50	185.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,3KGVF@43988|Cyanothece	1117|Cyanobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GZD2_k127_221685_2	926550.CLDAP_06970	1.463e-56	208.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
GZD2_k127_221685_1	926550.CLDAP_06960	8.076e-143	463.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_221685_0	926550.CLDAP_06990	2.472e-185	584.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GZD2_k127_224281_3	926569.ANT_06180	1.908e-60	221.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_224281_4	35754.JNYJ01000075_gene8651	1.91e-27	116.0	COG3474@1|root,COG3474@2|Bacteria,2HB9W@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
GZD2_k127_224281_1	536019.Mesop_4363	2.176e-77	271.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRS5@28211|Alphaproteobacteria,43KWE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
GZD2_k127_224281_0	1218084.BBJK01000014_gene1502	9.59e-228	733.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VM0G@28216|Betaproteobacteria,1K22G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1,COX3
GZD2_k127_224281_5	398527.Bphyt_0226	1.272e-19	94.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2VH58@28216|Betaproteobacteria,1K0HJ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
GZD2_k127_224281_2	1137271.AZUM01000002_gene2524	5.517e-66	245.0	COG4993@1|root,COG4993@2|Bacteria,2I3R4@201174|Actinobacteria,4EF6T@85010|Pseudonocardiales	201174|Actinobacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
GZD2_k127_2250349_1	765912.Thimo_0360	1.5e-55	204.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1MXRV@1224|Proteobacteria,1SEJ5@1236|Gammaproteobacteria,1WZGY@135613|Chromatiales	135613|Chromatiales	S	PFAM FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
GZD2_k127_2250349_0	1117318.PRUB_02474	2.067e-63	234.0	COG2110@1|root,COG2110@2|Bacteria,1RH4K@1224|Proteobacteria	1224|Proteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2250349_2	926550.CLDAP_33720	5.112e-40	156.0	COG1428@1|root,COG1428@2|Bacteria,2G8Z7@200795|Chloroflexi	200795|Chloroflexi	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GZD2_k127_2250349_3	65393.PCC7424_4937	7.387e-20	94.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
GZD2_k127_2263357_0	926569.ANT_15160	4.767e-130	421.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GZD2_k127_2263357_2	326427.Cagg_0444	3.005e-51	188.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi,375QR@32061|Chloroflexia	32061|Chloroflexia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
GZD2_k127_2263357_1	316274.Haur_4010	3.82e-73	256.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
GZD2_k127_2278870_0	698761.RTCIAT899_CH12595	1.633e-57	205.0	COG0125@1|root,COG0125@2|Bacteria,1QU31@1224|Proteobacteria,2TVX4@28211|Alphaproteobacteria,4BNPT@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
GZD2_k127_2278870_3	926569.ANT_29040	5.531e-10	64.0	COG3464@1|root,COG3464@2|Bacteria,2G9B1@200795|Chloroflexi	200795|Chloroflexi	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
GZD2_k127_2278870_2	926550.CLDAP_25230	2.065e-10	74.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GZD2_k127_2278870_1	335543.Sfum_2397	4.63e-18	93.0	COG0398@1|root,COG0398@2|Bacteria,1QKZU@1224|Proteobacteria,42SRQ@68525|delta/epsilon subdivisions,2WP35@28221|Deltaproteobacteria,2MQG7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD2_k127_2278870_5	1121403.AUCV01000030_gene2788	1.054e-05	57.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
GZD2_k127_2278870_4	416348.Hlac_2824	4.79e-08	64.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
GZD2_k127_2285823_14	1379698.RBG1_1C00001G0048	2.05e-24	103.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
GZD2_k127_2285823_9	429009.Adeg_2015	5.455e-56	201.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
GZD2_k127_2285823_0	693661.Arcve_1567	3.09e-242	765.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_2285823_7	1379698.RBG1_1C00001G0051	3.352e-75	266.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
GZD2_k127_2285823_12	1379698.RBG1_1C00001G0052	5.349e-34	139.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
GZD2_k127_2285823_3	926569.ANT_21940	4.89e-186	597.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
GZD2_k127_2285823_5	926569.ANT_26970	1.697e-111	374.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
GZD2_k127_2285823_6	926569.ANT_26980	3.795e-108	364.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
GZD2_k127_2285823_4	926569.ANT_17310	3.696e-153	492.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD2_k127_2285823_16	83406.HDN1F_34800	1.873e-09	66.0	2DSPU@1|root,33GZC@2|Bacteria,1NJ5W@1224|Proteobacteria,1SHAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GZD2_k127_2285823_11	926569.ANT_30860	1.911e-43	172.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD2_k127_2285823_10	926569.ANT_30860	2.348e-51	190.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD2_k127_2285823_15	264732.Moth_1227	5.434e-12	70.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
GZD2_k127_2285823_2	926569.ANT_00270	3.141e-209	659.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GZD2_k127_2285823_13	1286171.EAL2_c20200	8.463e-26	111.0	COG0399@1|root,COG0399@2|Bacteria,1VGIE@1239|Firmicutes,24PJD@186801|Clostridia	186801|Clostridia	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_2285823_8	926569.ANT_04640	2.5e-56	205.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2285823_1	926569.ANT_04650	1.389e-230	719.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
GZD2_k127_228871_3	1535287.JP74_15220	2.367e-55	224.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,3N7W7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD2_k127_228871_2	1306406.ASHX01000001_gene4469	5.998e-68	265.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF11,PKD,PPC
GZD2_k127_228871_1	439235.Dalk_2056	3.168e-101	339.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,42SS9@68525|delta/epsilon subdivisions,2WPND@28221|Deltaproteobacteria,2MK6P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
GZD2_k127_228871_4	696281.Desru_3298	1.254e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,1VJ8P@1239|Firmicutes,25BNH@186801|Clostridia,26740@186807|Peptococcaceae	186801|Clostridia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD2_k127_228871_5	383372.Rcas_0576	1.384e-13	77.0	COG1708@1|root,COG1708@2|Bacteria,2G9B2@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
GZD2_k127_228871_0	557599.MKAN_23440	1.972e-243	825.0	COG2351@1|root,COG2351@2|Bacteria,2H2SD@201174|Actinobacteria	201174|Actinobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VRP1
GZD2_k127_2317534_0	926569.ANT_30670	5.013e-213	667.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GZD2_k127_2317534_1	926569.ANT_12920	9.616e-92	315.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
GZD2_k127_2317534_2	357808.RoseRS_3344	6.226e-69	242.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GZD2_k127_2317534_3	926569.ANT_25700	5.799e-27	116.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GZD2_k127_232426_2	765420.OSCT_1671	3.602e-14	79.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_232426_1	1131553.JIBI01000010_gene1371	1.819e-24	106.0	2E75R@1|root,331PX@2|Bacteria,1NAGT@1224|Proteobacteria,2W4DV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_232426_0	385682.AFSL01000060_gene1832	3.274e-106	364.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,2FMDF@200643|Bacteroidia,3XJTE@558415|Marinilabiliaceae	976|Bacteroidetes	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
GZD2_k127_2329795_2	926569.ANT_09730	1.151e-59	213.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
GZD2_k127_2329795_0	926569.ANT_09740	4.966e-123	398.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
GZD2_k127_2329795_4	592015.HMPREF1705_01323	5.8e-18	89.0	COG0851@1|root,COG0851@2|Bacteria,3TBIQ@508458|Synergistetes	508458|Synergistetes	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
GZD2_k127_2329795_1	926569.ANT_09760	3.081e-119	396.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
GZD2_k127_2329795_3	926569.ANT_09770	3.764e-22	96.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GZD2_k127_2329886_2	1227352.C173_31851	2.206e-36	149.0	COG0457@1|root,COG0457@2|Bacteria,1U1NV@1239|Firmicutes,4IB5C@91061|Bacilli,273QU@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2329886_0	926569.ANT_17710	3.74e-140	452.0	COG1216@1|root,COG1216@2|Bacteria,2G961@200795|Chloroflexi	200795|Chloroflexi	H	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_2329886_3	269798.CHU_0442	2.008e-10	64.0	2DSH0@1|root,33G3J@2|Bacteria,4NXV6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2329886_1	926569.ANT_22190	2.089e-86	300.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_2340607_4	1194165.CAJF01000038_gene3421	0.0001721	50.0	29YCS@1|root,30K75@2|Bacteria,2IJFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2340607_3	886379.AEWI01000022_gene192	8.858e-44	163.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,2FYEV@200643|Bacteroidia,3XKTU@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GZD2_k127_2340607_2	485913.Krac_1964	3.273e-48	177.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_2340607_1	926569.ANT_18050	6.983e-114	374.0	COG1940@1|root,COG1940@2|Bacteria,2G7MR@200795|Chloroflexi	200795|Chloroflexi	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
GZD2_k127_2340607_0	1128421.JAGA01000004_gene2611	1.086e-147	481.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
GZD2_k127_2349661_0	459495.SPLC1_S020090	3.945e-139	454.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1G2KN@1117|Cyanobacteria,1HBXR@1150|Oscillatoriales	1117|Cyanobacteria	EH	Amino-transferase class IV	-	-	2.6.1.85,4.1.3.38	ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
GZD2_k127_2349661_10	1122917.KB899659_gene5390	5.491e-13	74.0	COG5652@1|root,COG5652@2|Bacteria,1VGDJ@1239|Firmicutes,4HNZ0@91061|Bacilli,26Z72@186822|Paenibacillaceae	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
GZD2_k127_2349661_4	926569.ANT_22490	1.295e-66	235.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GZD2_k127_2349661_5	926569.ANT_22480	1.968e-64	224.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GZD2_k127_2349661_7	1279017.AQYJ01000020_gene1340	3.023e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,1S5VV@1236|Gammaproteobacteria,46AM9@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_2349661_9	926569.ANT_22470	8.201e-19	88.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GZD2_k127_2349661_3	926569.ANT_22470	6.185e-68	234.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GZD2_k127_2349661_1	221360.RS9917_05080	1.236e-136	446.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1GZS9@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GZD2_k127_2349661_8	926569.ANT_04540	3.382e-41	154.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GZD2_k127_2349661_2	926569.ANT_04550	2.407e-68	240.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GZD2_k127_2349661_6	926569.ANT_04560	9.295e-61	212.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
GZD2_k127_2365346_1	99598.Cal7507_0697	3.109e-40	153.0	2DQ25@1|root,334FF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2365346_0	1499967.BAYZ01000171_gene5553	6.109e-89	306.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_2365346_2	29760.VIT_19s0085g01130.t01	1.708e-17	88.0	KOG3371@1|root,KOG3371@2759|Eukaryota,37UAN@33090|Viridiplantae,3GI5A@35493|Streptophyta	35493|Streptophyta	S	UPF0678 fatty acid-binding protein-like protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	DUF1794
GZD2_k127_2370795_0	926569.ANT_16960	5.477e-198	626.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GZD2_k127_2370795_1	926569.ANT_16940	2.83e-120	399.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_2370795_2	1128421.JAGA01000001_gene2396	1.023e-83	290.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
GZD2_k127_2370795_3	926569.ANT_16920	7.462e-29	117.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GZD2_k127_2382492_0	926550.CLDAP_05850	1.168e-59	211.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GZD2_k127_2402641_3	926569.ANT_30130	2.913e-19	93.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GZD2_k127_2402641_1	926569.ANT_30120	9.555e-73	259.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GZD2_k127_2402641_2	926550.CLDAP_10230	9.329e-26	116.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
GZD2_k127_2402641_0	926569.ANT_30110	3.85e-73	254.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
GZD2_k127_2454680_1	926550.CLDAP_29010	1.951e-126	411.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reversible oxidation of malate to oxaloacetate	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
GZD2_k127_2454680_0	584708.Apau_1512	1.191e-144	479.0	COG0465@1|root,COG0465@2|Bacteria,3T9TM@508458|Synergistetes	508458|Synergistetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GZD2_k127_2454680_2	1128421.JAGA01000002_gene1198	2.213e-39	151.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K15945	ko01057,ko01130,map01057,map01130	-	R09330	RC00046	ko00000,ko00001	-	-	-	SnoaL,SnoaL_2
GZD2_k127_2454680_3	926569.ANT_03450	2.197e-15	76.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GZD2_k127_2457238_0	926569.ANT_15160	5.173e-169	539.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
GZD2_k127_2457238_2	926569.ANT_15150	6.404e-95	319.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GZD2_k127_2457238_1	926569.ANT_15140	1.415e-126	421.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
GZD2_k127_2457238_4	926569.ANT_15130	9.671e-45	168.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD2_k127_2457238_7	926569.ANT_15120	4.415e-23	100.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2457238_3	926569.ANT_15110	9.664e-70	239.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_2457238_5	926569.ANT_15110	1.547e-39	147.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_2457238_6	926550.CLDAP_01300	4.05e-37	145.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD2_k127_2457238_8	1123276.KB893272_gene2436	0.0003718	44.0	COG3385@1|root,COG3385@2|Bacteria,4P02Y@976|Bacteroidetes,47TUA@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GZD2_k127_2478757_2	351160.RCIX701	5.242e-29	120.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GZD2_k127_2478757_3	1034943.BN1094_01655	8.078e-26	112.0	2ERG8@1|root,33J1S@2|Bacteria,1NMXE@1224|Proteobacteria,1SVEJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
GZD2_k127_2478757_1	485913.Krac_2176	5.515e-75	261.0	COG3173@1|root,COG3173@2|Bacteria,2G7IQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD2_k127_2478757_4	1499968.TCA2_3156	4.932e-15	81.0	2FC4Z@1|root,3448W@2|Bacteria,1U2X0@1239|Firmicutes,4ICJY@91061|Bacilli,272JJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2478757_0	1380390.JIAT01000011_gene2759	1.667e-304	957.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GZD2_k127_2479318_4	926569.ANT_16180	2.751e-98	326.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GZD2_k127_2479318_0	926569.ANT_16170	1.088e-214	674.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GZD2_k127_2479318_12	269797.Mbar_A0916	3.603e-07	59.0	COG5513@1|root,arCOG03547@2157|Archaea,2Y4G7@28890|Euryarchaeota,2NB6K@224756|Methanomicrobia	224756|Methanomicrobia	G	serine-type aminopeptidase activity	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	-
GZD2_k127_2479318_2	459349.CLOAM0239	2.732e-140	484.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Peptidase_M6
GZD2_k127_2479318_8	1504981.KO116_2279	9.344e-14	72.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,YHS
GZD2_k127_2479318_10	1380391.JIAS01000014_gene2298	4.359e-11	64.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2JPCQ@204441|Rhodospirillales	204441|Rhodospirillales	P	COG2217 Cation transport ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
GZD2_k127_2479318_6	329726.AM1_4674	8.481e-58	212.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_2479318_11	886293.Sinac_3220	2.017e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,2IX04@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2479318_3	926569.ANT_02010	1.327e-127	412.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GZD2_k127_2479318_7	378806.STAUR_3873	2.749e-42	167.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,42UMK@68525|delta/epsilon subdivisions,2WQNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD2_k127_2479318_9	118163.Ple7327_0957	5.183e-13	75.0	2B1XW@1|root,31UE7@2|Bacteria,1G79D@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_2479318_1	926569.ANT_02020	5.658e-151	481.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GZD2_k127_2479318_5	1122223.KB890692_gene3011	1.052e-79	274.0	COG4106@1|root,COG4106@2|Bacteria,1WMC7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Methyltransferase domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
GZD2_k127_2486272_7	1132442.KB889752_gene1431	1.946e-24	104.0	COG4922@1|root,COG4922@2|Bacteria,1V6S2@1239|Firmicutes,4HJRI@91061|Bacilli,1ZGJ4@1386|Bacillus	91061|Bacilli	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
GZD2_k127_2486272_3	42345.XP_008808703.1	1.374e-57	207.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta,3KUNC@4447|Liliopsida	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
GZD2_k127_2486272_6	797209.ZOD2009_19388	9.031e-38	151.0	COG2820@1|root,arCOG01324@2157|Archaea,2Y06F@28890|Euryarchaeota,23W2X@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GZD2_k127_2486272_2	945713.IALB_2765	3.313e-59	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD2_k127_2486272_0	479434.Sthe_3413	1.779e-206	653.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
GZD2_k127_2486272_4	479434.Sthe_3414	1.496e-57	211.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2,UPF0158
GZD2_k127_2486272_5	1392488.JHZY01000002_gene1327	2.044e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,4NHDI@976|Bacteroidetes,1HXX0@117743|Flavobacteriia,2XI6K@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
GZD2_k127_2486272_1	1120968.AUBX01000010_gene847	2.495e-89	321.0	COG5617@1|root,COG5617@2|Bacteria,4NFUV@976|Bacteroidetes,47NE1@768503|Cytophagia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2486549_0	290397.Adeh_2304	7.655e-279	867.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_2486549_5	1123320.KB889674_gene4180	1.918e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GZD2_k127_2486549_8	666686.B1NLA3E_21855	3.11e-14	78.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,1ZI2E@1386|Bacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD2_k127_2486549_7	1173263.Syn7502_02730	2.299e-21	96.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
GZD2_k127_2486549_6	765911.Thivi_0478	1.354e-22	102.0	COG3039@1|root,COG3039@2|Bacteria,1N88K@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
GZD2_k127_2486549_2	604354.TSIB_0930	7.463e-82	279.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_2486549_3	1382356.JQMP01000003_gene1742	2.593e-56	201.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_2486549_1	861299.J421_0680	8.696e-106	353.0	COG2072@1|root,COG2072@2|Bacteria,1ZV84@142182|Gemmatimonadetes	2|Bacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
GZD2_k127_2486549_4	383372.Rcas_1765	7.056e-36	152.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GZD2_k127_2486549_9	903818.KI912268_gene963	9.159e-05	48.0	COG1131@1|root,COG1131@2|Bacteria,3Y725@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_2487980_1	926569.ANT_24790	2.026e-89	301.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi	200795|Chloroflexi	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
GZD2_k127_2487980_3	926569.ANT_24800	4.042e-55	199.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GZD2_k127_2487980_2	1128398.Curi_c00320	1.708e-80	278.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,269WM@186813|unclassified Clostridiales	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
GZD2_k127_2487980_4	405948.SACE_4239	3.312e-06	54.0	COG2963@1|root,COG2963@2|Bacteria,2GRP3@201174|Actinobacteria	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
GZD2_k127_2487980_0	926569.ANT_11050	6.83e-93	308.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GZD2_k127_2491676_1	867845.KI911784_gene1260	1.704e-148	496.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
GZD2_k127_2491676_3	1150398.JIBJ01000006_gene3499	7.405e-07	59.0	2DIQ5@1|root,32UBF@2|Bacteria,2IMKR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2491676_2	926569.ANT_24700	3.731e-147	473.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
GZD2_k127_2491676_0	926569.ANT_03460	5.503e-238	748.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD2_k127_2499365_2	485913.Krac_3483	2.001e-80	274.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GZD2_k127_2499365_1	1192034.CAP_8417	8.269e-89	300.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
GZD2_k127_2499365_0	1122915.AUGY01000018_gene6291	6.131e-108	361.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,26VDY@186822|Paenibacillaceae	91061|Bacilli	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD2_k127_2508154_2	1121374.KB891585_gene2413	3.64e-58	207.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
GZD2_k127_2508154_1	1120950.KB892757_gene6526	5.812e-102	341.0	COG0667@1|root,COG0667@2|Bacteria,2I8JM@201174|Actinobacteria,4DWPN@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_2508154_0	926569.ANT_14150	1.318e-127	417.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
GZD2_k127_2508435_2	1123400.KB904791_gene33	3.227e-05	56.0	2DS98@1|root,33F2N@2|Bacteria,1NJKA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
GZD2_k127_2508435_0	526227.Mesil_0601	7.556e-202	639.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
GZD2_k127_2508435_1	1499967.BAYZ01000018_gene6344	1.558e-14	74.0	COG3191@1|root,COG3191@2|Bacteria,2NNR0@2323|unclassified Bacteria	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GZD2_k127_2508642_1	926569.ANT_10870	1.711e-78	279.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GZD2_k127_2508642_0	926569.ANT_11200	6.285e-146	482.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
GZD2_k127_2508642_2	1500259.JQLD01000004_gene1366	0.0006968	44.0	COG4320@1|root,COG4320@2|Bacteria,1P9GA@1224|Proteobacteria,2TV6P@28211|Alphaproteobacteria,4B85E@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
GZD2_k127_2512968_0	518766.Rmar_1363	9.81e-290	911.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_2512968_1	485917.Phep_1725	4.267e-93	312.0	COG4221@1|root,COG4221@2|Bacteria,4NM3C@976|Bacteroidetes,1ISIS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_2513735_6	1254432.SCE1572_34730	4.022e-21	103.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like,Lycopene_cycl
GZD2_k127_2513735_4	926569.ANT_08620	9.017e-93	311.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GZD2_k127_2513735_5	926569.ANT_08630	1.06e-45	169.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
GZD2_k127_2513735_3	1145276.T479_00340	2.491e-128	424.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3IWNF@400634|Lysinibacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
GZD2_k127_2513735_7	760117.JN27_14915	4.437e-13	81.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2W1GP@28216|Betaproteobacteria,4764V@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GZD2_k127_2513735_1	926569.ANT_01410	4.263e-170	539.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD2_k127_2513735_2	926569.ANT_01400	1.993e-160	511.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD2_k127_2513735_0	926569.ANT_31100	1.154e-172	560.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_2529506_3	545693.BMQ_3138	6.643e-21	98.0	COG0500@1|root,COG2226@2|Bacteria,1V5IF@1239|Firmicutes,4HHR9@91061|Bacilli,1ZQ1Y@1386|Bacillus	91061|Bacilli	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_2529506_1	1120985.AUMI01000012_gene16	3.755e-36	147.0	2DPHF@1|root,33237@2|Bacteria	2|Bacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
GZD2_k127_2529506_0	1035308.AQYY01000001_gene2876	3.468e-70	246.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,261X6@186807|Peptococcaceae	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
GZD2_k127_2529506_2	1297742.A176_04679	4.336e-23	103.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,430U9@68525|delta/epsilon subdivisions,2WW0M@28221|Deltaproteobacteria,2YXV8@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_254979_3	926569.ANT_20920	0.0001164	46.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GZD2_k127_254979_2	926569.ANT_20910	1.334e-103	345.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GZD2_k127_254979_1	324925.Ppha_2833	8.265e-174	562.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD2_k127_254979_0	926569.ANT_20890	6.928e-238	741.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GZD2_k127_2552202_4	1476876.JOJO01000017_gene1563	6.872e-09	68.0	2DBRU@1|root,2ZANA@2|Bacteria,2GP2Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2552202_3	1440053.JOEI01000013_gene4948	3.634e-14	82.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_2552202_1	639030.JHVA01000001_gene3632	3.986e-49	184.0	COG1215@1|root,COG1215@2|Bacteria,3Y3PN@57723|Acidobacteria,2JHSE@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_2552202_0	926569.ANT_06560	2.525e-72	263.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
GZD2_k127_2552202_2	926569.ANT_06540	1.841e-35	141.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_2552554_1	1128421.JAGA01000003_gene3550	1.02e-66	233.0	COG0277@1|root,COG0277@2|Bacteria,2NQTQ@2323|unclassified Bacteria	2|Bacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GZD2_k127_2552554_2	485913.Krac_0922	3.092e-34	134.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_2552554_0	926569.ANT_12750	1.62e-131	429.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
GZD2_k127_2561512_1	889378.Spiaf_1153	5.135e-46	171.0	COG3833@1|root,COG3833@2|Bacteria,2J6AB@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GZD2_k127_2561512_0	1125973.JNLC01000009_gene197	9.577e-98	337.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria	1224|Proteobacteria	P	transport	malF	GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351	-	ko:K02025,ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	iZ_1308.Z5631	BPD_transp_1,MalF_P2
GZD2_k127_2561512_2	1125973.JNLC01000009_gene196	6.973e-14	72.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K05813,ko:K15770	ko02010,map02010	M00198,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_2565892_5	1524467.IV04_10320	5.229e-15	83.0	2DC1F@1|root,2ZCE5@2|Bacteria,1RCQ9@1224|Proteobacteria,1S28C@1236|Gammaproteobacteria,400VF@613|Serratia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
GZD2_k127_2565892_0	525904.Tter_2236	6.066e-88	302.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD2_k127_2565892_3	1382306.JNIM01000001_gene2450	5.854e-24	107.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GZD2_k127_2565892_7	33898.JRHJ01000010_gene5061	2.14e-07	55.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD2_k127_2565892_1	518766.Rmar_2770	4.604e-47	177.0	COG1975@1|root,COG2608@1|root,COG1975@2|Bacteria,COG2608@2|Bacteria,4NP35@976|Bacteroidetes	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
GZD2_k127_2565892_2	1380391.JIAS01000014_gene2202	1.214e-44	165.0	COG0251@1|root,COG0251@2|Bacteria,1RD2M@1224|Proteobacteria,2U7PE@28211|Alphaproteobacteria,2JTUT@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD2_k127_2565892_4	479434.Sthe_2778	7.603e-18	85.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD2_k127_2565892_6	1232410.KI421421_gene3682	8.004e-11	63.0	COG0454@1|root,COG0456@2|Bacteria,1NEWG@1224|Proteobacteria,42VG1@68525|delta/epsilon subdivisions,2WRCC@28221|Deltaproteobacteria,43UQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
GZD2_k127_2584939_1	1121380.JNIW01000033_gene3726	2.505e-120	393.0	COG0161@1|root,COG0161@2|Bacteria,1WISD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
GZD2_k127_2584939_0	476272.RUMHYD_02346	2.664e-150	486.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD2_k127_2584939_5	1121456.ATVA01000018_gene331	7.061e-12	72.0	COG1522@1|root,COG1522@2|Bacteria,1N48I@1224|Proteobacteria,42TMQ@68525|delta/epsilon subdivisions,2WR1Q@28221|Deltaproteobacteria,2MB8N@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GZD2_k127_2584939_3	926569.ANT_25400	1.799e-61	220.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
GZD2_k127_2584939_4	1382356.JQMP01000003_gene1854	4.499e-41	160.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	189775|Thermomicrobia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GZD2_k127_2584939_2	204669.Acid345_0734	4.09e-101	344.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
GZD2_k127_2586375_1	485913.Krac_11884	1.277e-47	176.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GZD2_k127_2586375_2	1121904.ARBP01000008_gene3289	7.406e-17	93.0	COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
GZD2_k127_2586375_0	926550.CLDAP_20690	4.182e-95	324.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
GZD2_k127_2593636_2	765420.OSCT_1671	1.503e-06	55.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_2593636_0	1128421.JAGA01000002_gene693	1.357e-78	270.0	COG0566@1|root,COG0566@2|Bacteria,2NR96@2323|unclassified Bacteria	2|Bacteria	J	SpoU rRNA Methylase family	spoU	-	2.1.1.185,2.1.1.208	ko:K03218,ko:K03437,ko:K21514	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GZD2_k127_2593636_1	484019.THA_30	4.907e-43	160.0	COG4608@1|root,COG4608@2|Bacteria,2GC6X@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD2_k127_259648_1	926550.CLDAP_37400	7.613e-133	441.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_259648_6	485913.Krac_5508	5.146e-21	98.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
GZD2_k127_259648_4	1121939.L861_17340	1.735e-41	156.0	COG1720@1|root,COG1720@2|Bacteria,1PIZG@1224|Proteobacteria,1SAX2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
GZD2_k127_259648_2	485913.Krac_0278	6.196e-119	390.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GZD2_k127_259648_0	196490.AUEZ01000042_gene7227	0.0	1112.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD2_k127_259648_3	309801.trd_0578	1.353e-73	250.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GZD2_k127_259648_5	1298867.AUES01000006_gene345	9.88e-35	137.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD2_k127_261413_1	65393.PCC7424_0063	8.51e-62	219.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3KJY9@43988|Cyanothece	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
GZD2_k127_261413_2	452637.Oter_4516	1.729e-56	208.0	COG2819@1|root,COG2819@2|Bacteria,46W78@74201|Verrucomicrobia,3K9WA@414999|Opitutae	414999|Opitutae	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
GZD2_k127_261413_0	926569.ANT_22760	9.257e-99	331.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	MFS_1
GZD2_k127_2614437_7	886293.Sinac_4680	2.274e-14	81.0	COG4932@1|root,COG4932@2|Bacteria,2IYDU@203682|Planctomycetes	203682|Planctomycetes	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
GZD2_k127_2614437_2	399549.Msed_0010	3.992e-53	192.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
GZD2_k127_2614437_1	926569.ANT_26230	2.284e-124	412.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GZD2_k127_2614437_9	629773.AORY01000014_gene2544	1.968e-07	55.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GZD2_k127_2614437_4	926569.ANT_26250	6.076e-46	171.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
GZD2_k127_2614437_8	326427.Cagg_2197	1.587e-10	63.0	2EPAC@1|root,33GX3@2|Bacteria,2GB3X@200795|Chloroflexi,377VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2614437_0	926569.ANT_25910	1.734e-149	489.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GZD2_k127_2614437_3	1380391.JIAS01000012_gene4124	1.787e-51	196.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,2JXWG@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
GZD2_k127_2614437_5	335541.Swol_1996	3.076e-37	163.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
GZD2_k127_2614437_6	1123508.JH636439_gene1332	9.107e-30	128.0	COG1502@1|root,COG1502@2|Bacteria,2IZPW@203682|Planctomycetes	203682|Planctomycetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD2_k127_2617694_3	65497.JODV01000006_gene866	1.204e-38	151.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4E17N@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K17203	ko02010,map02010	M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.11,3.A.1.2.16	-	-	BPD_transp_2
GZD2_k127_2617694_0	262543.Exig_2385	7.207e-147	481.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3WFBH@539002|Bacillales incertae sedis	91061|Bacilli	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GZD2_k127_2617694_1	65497.JODV01000006_gene868	8.234e-74	259.0	COG1879@1|root,COG1879@2|Bacteria,2I43Z@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GZD2_k127_2617694_2	358823.DF19_04755	1.2e-70	246.0	COG4126@1|root,COG4126@2|Bacteria,2IFSR@201174|Actinobacteria	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
GZD2_k127_2617694_4	1320556.AVBP01000002_gene4071	9.753e-26	116.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2TV1R@28211|Alphaproteobacteria,43HJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	transcriptional	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GZD2_k127_2626954_1	1206731.BAGB01000054_gene3775	2.127e-78	268.0	COG2013@1|root,COG2013@2|Bacteria,2IA2I@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
GZD2_k127_2626954_0	485913.Krac_11103	1.026e-101	342.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_2626954_2	1121481.AUAS01000006_gene588	5.805e-30	122.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
GZD2_k127_2630620_1	472759.Nhal_2157	4.989e-63	219.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales	135613|Chromatiales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GZD2_k127_2630620_0	1219084.AP014508_gene244	3.356e-132	437.0	COG2211@1|root,COG2211@2|Bacteria,2GCKM@200918|Thermotogae	200918|Thermotogae	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
GZD2_k127_2630620_2	273068.TTE1931	4.88e-38	147.0	2EWYX@1|root,33QA8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2640874_1	350054.Mflv_4295	1.004e-73	274.0	COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,235HD@1762|Mycobacteriaceae	201174|Actinobacteria	L	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,PD40,TIR_2,WD40
GZD2_k127_2640874_0	926569.ANT_00900	9.811e-210	660.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GZD2_k127_265127_2	926569.ANT_12480	7.006e-55	200.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD2_k127_265127_1	1121451.DESAM_22149	1.56e-67	238.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_265127_3	243231.GSU1293	8.84e-26	113.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_265127_4	1521187.JPIM01000149_gene405	3.917e-14	83.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
GZD2_k127_265127_0	290397.Adeh_2907	2.325e-85	293.0	COG3005@1|root,COG3005@2|Bacteria,1NT6I@1224|Proteobacteria,42YAG@68525|delta/epsilon subdivisions,2WTY3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2653470_5	311403.Arad_9447	5.518e-23	103.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,4BFNA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_2653470_3	457570.Nther_2154	1.086e-79	274.0	COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia	186801|Clostridia	GM	phosphoenolpyruvate	prpB	-	4.1.3.30,4.1.3.32	ko:K03417,ko:K20454	ko00640,ko00760,ko01120,map00640,map00760,map01120	-	R00409,R01355	RC00286,RC00287,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
GZD2_k127_2653470_2	316274.Haur_2265	8.658e-108	362.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_8
GZD2_k127_2653470_0	316274.Haur_2266	3.86e-171	554.0	COG1178@1|root,COG1178@2|Bacteria,2G6VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
GZD2_k127_2653470_1	316274.Haur_2267	3.515e-114	378.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi,37726@32061|Chloroflexia	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
GZD2_k127_2653470_4	1266925.JHVX01000004_gene1280	7.836e-24	102.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,372F8@32003|Nitrosomonadales	28216|Betaproteobacteria	S	MmgE/PrpD family	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GZD2_k127_2656757_4	639283.Snov_0200	1.556e-53	195.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3F1EG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
GZD2_k127_2656757_2	351607.Acel_0890	6.484e-110	368.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4EU2M@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Hydrolase_4
GZD2_k127_2656757_3	684949.ATTJ01000001_gene903	1.626e-62	222.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_2656757_1	709986.Deima_0441	1.471e-112	381.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA_3
GZD2_k127_2656757_7	1408433.JHXV01000005_gene2482	4.58e-29	126.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD2_k127_2656757_5	1536774.H70357_27195	4.627e-30	129.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_2656757_0	383372.Rcas_0372	0.0	1328.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi,37711@32061|Chloroflexia	32061|Chloroflexia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD2_k127_2659698_5	1005395.CSV86_02087	0.0002575	49.0	2AMMT@1|root,31CHW@2|Bacteria,1Q8VV@1224|Proteobacteria,1TKFI@1236|Gammaproteobacteria,1YVJU@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	PFAM Type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
GZD2_k127_2659698_1	44251.PDUR_26510	2.962e-54	205.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,26SCW@186822|Paenibacillaceae	91061|Bacilli	E	Spermidine putrescine ABC transporter substrate-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iSB619.SA_RS05395	SBP_bac_8
GZD2_k127_2659698_2	935261.JAGL01000005_gene3409	1.388e-52	197.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,43H7C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GZD2_k127_2659698_0	1207063.P24_08619	6.639e-59	214.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,2JQTE@204441|Rhodospirillales	204441|Rhodospirillales	E	Putrescine transport system permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GZD2_k127_2659698_3	1040983.AXAE01000001_gene2670	3.346e-45	175.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TS7M@28211|Alphaproteobacteria,43R9I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
GZD2_k127_2659818_1	1150398.JIBJ01000007_gene269	5.57e-49	181.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GZD2_k127_2659818_0	1123368.AUIS01000003_gene1806	6.633e-67	235.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
GZD2_k127_2659818_2	266117.Rxyl_1792	7.11e-26	111.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GZD2_k127_267422_3	926550.CLDAP_13360	5.921e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GZD2_k127_267422_2	484770.UFO1_1182	3.764e-83	282.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_267422_0	485916.Dtox_1611	3.258e-113	372.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
GZD2_k127_267422_4	1206733.BAGC01000040_gene1764	3.26e-16	86.0	2E8H6@1|root,332VD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_267422_1	926569.ANT_19840	3.699e-102	336.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
GZD2_k127_2684379_1	292415.Tbd_1055	2.286e-48	177.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria,2VTFD@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD2_k127_2684379_0	1128421.JAGA01000002_gene1768	6.286e-109	366.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD2_k127_2684379_2	388413.ALPR1_07280	3.022e-07	54.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,47VEE@768503|Cytophagia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_2691255_5	926569.ANT_28110	5.909e-23	100.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GZD2_k127_2691255_3	926569.ANT_04240	1.836e-46	181.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD2_k127_2691255_1	926569.ANT_11940	1.51e-116	381.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GZD2_k127_2691255_0	926569.ANT_11950	7.569e-273	851.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GZD2_k127_2691255_4	65393.PCC7424_0020	1.14e-37	160.0	COG1807@1|root,COG1807@2|Bacteria,1GM4D@1117|Cyanobacteria,3KJ81@43988|Cyanothece	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2691255_2	926569.ANT_11960	8.02e-110	358.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GZD2_k127_2693721_0	1291050.JAGE01000001_gene2731	5.332e-216	696.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyltransferase family 36	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
GZD2_k127_2693721_2	867845.KI911784_gene2744	1.707e-46	178.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
GZD2_k127_2693721_1	926550.CLDAP_00330	1.184e-184	587.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GZD2_k127_2693721_3	1521187.JPIM01000005_gene2268	1.249e-17	85.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1609@1|root,COG2207@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1609@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02529,ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,Cupin_2,HATPase_c,HTH_18,HisKA,Peripla_BP_3,Response_reg
GZD2_k127_2698192_1	479434.Sthe_2326	2.773e-58	208.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
GZD2_k127_2698192_0	479434.Sthe_2327	1.499e-117	395.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GZD2_k127_2698192_2	1356854.N007_03980	1.777e-50	183.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,277VH@186823|Alicyclobacillaceae	91061|Bacilli	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
GZD2_k127_2704341_3	46234.ANA_C10109	4.735e-36	141.0	COG1943@1|root,COG1943@2|Bacteria,1G7D3@1117|Cyanobacteria,1HU60@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GZD2_k127_2704341_0	1123242.JH636436_gene541	2.016e-106	351.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2704341_4	1123368.AUIS01000019_gene1214	2.945e-12	68.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD2_k127_2704341_2	118173.KB235910_gene4397	5.169e-48	178.0	COG1943@1|root,COG1943@2|Bacteria,1G5Z6@1117|Cyanobacteria,1HBEU@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GZD2_k127_2704341_1	463191.SSEG_05814	3.583e-92	313.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria	201174|Actinobacteria	S	Neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
GZD2_k127_2709486_1	491915.Aflv_1247	6.778e-41	168.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA0E@91061|Bacilli,21W1S@150247|Anoxybacillus	91061|Bacilli	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
GZD2_k127_2709486_0	1121920.AUAU01000004_gene859	1.205e-78	265.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GZD2_k127_2712362_1	926569.ANT_09700	2.788e-83	284.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
GZD2_k127_2712362_0	926569.ANT_09690	1.419e-157	502.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GZD2_k127_2723635_5	316274.Haur_3580	8.575e-64	232.0	COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia	32061|Chloroflexia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
GZD2_k127_2723635_6	1286631.X805_12650	2.228e-59	220.0	COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,2VZZD@28216|Betaproteobacteria,1KN17@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
GZD2_k127_2723635_7	1123401.JHYQ01000002_gene2696	1.292e-58	215.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,1SAZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2723635_1	357808.RoseRS_1075	5.619e-152	509.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_2723635_2	357808.RoseRS_3212	3.676e-122	403.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GZD2_k127_2723635_9	319236.JCM19294_2863	5.341e-09	68.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia,3HK24@363408|Nonlabens	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
GZD2_k127_2723635_8	1121373.KB903624_gene2429	1.114e-45	169.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,47R8X@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD2_k127_2723635_4	113395.AXAI01000002_gene5399	4.051e-70	244.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,3K6HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GZD2_k127_2723635_0	1123252.ATZF01000013_gene2813	1.103e-209	665.0	COG4188@1|root,COG4188@2|Bacteria,1TXGH@1239|Firmicutes,4I6F9@91061|Bacilli,27CYA@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
GZD2_k127_2723635_3	926569.ANT_02850	2.592e-109	359.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GZD2_k127_2726215_2	1123288.SOV_5c02610	9.883e-08	64.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4H5IQ@909932|Negativicutes	909932|Negativicutes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GZD2_k127_2726215_1	491915.Aflv_1944	1.455e-11	76.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,21WKS@150247|Anoxybacillus	91061|Bacilli	M	NlpC/P60 family	-	-	-	ko:K19223,ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	Cu_amine_oxidN1,LysM,NLPC_P60,PG_binding_1
GZD2_k127_2726215_0	479434.Sthe_1621	0.0	1017.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
GZD2_k127_2732253_3	926569.ANT_14330	5.417e-35	138.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GZD2_k127_2732253_2	926569.ANT_14320	3.565e-40	152.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
GZD2_k127_2732253_0	926569.ANT_14310	1.611e-114	376.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
GZD2_k127_2732253_1	1499967.BAYZ01000038_gene2261	6.317e-94	312.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GZD2_k127_2737129_5	926569.ANT_12210	1.215e-20	101.0	COG1653@1|root,COG1653@2|Bacteria,2G7EJ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
GZD2_k127_2737129_4	926569.ANT_04050	4.19e-93	316.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GZD2_k127_2737129_0	926569.ANT_04040	1.473e-203	641.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_2737129_1	926569.ANT_04030	3.429e-155	494.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_2737129_2	926569.ANT_04020	3.842e-136	438.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_2737129_3	383372.Rcas_1884	6.139e-119	384.0	COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
GZD2_k127_2737425_2	123214.PERMA_1534	1.034e-59	224.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
GZD2_k127_2737425_4	526225.Gobs_0746	1.745e-30	125.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
GZD2_k127_2737425_1	926569.ANT_03930	7.321e-90	301.0	COG1045@1|root,COG1045@2|Bacteria,2G6DI@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
GZD2_k127_2737425_0	748280.NH8B_3175	4.009e-154	494.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,2KPYW@206351|Neisseriales	206351|Neisseriales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_2737425_3	756067.MicvaDRAFT_2673	2.254e-48	184.0	COG2199@1|root,COG3706@2|Bacteria,1G4J1@1117|Cyanobacteria,1HAAJ@1150|Oscillatoriales	1117|Cyanobacteria	T	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD2_k127_2738875_1	1444309.JAQG01000164_gene1837	2.4e-146	482.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
GZD2_k127_2738875_0	1266925.JHVX01000001_gene2544	4.333e-158	514.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,372T7@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Alpha-amylase domain	aglA	-	3.2.1.10,3.2.1.20	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
GZD2_k127_2738875_2	926569.ANT_16840	2.197e-143	468.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GZD2_k127_2754311_7	344747.PM8797T_16887	0.0005991	53.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_2754311_0	926569.ANT_00880	9.477e-194	625.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GZD2_k127_2754311_2	926569.ANT_16300	2.215e-113	372.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
GZD2_k127_2754311_5	1254432.SCE1572_23640	2.712e-46	183.0	29BBV@1|root,2ZCHD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GZD2_k127_2754311_4	272134.KB731324_gene1337	4.53e-56	201.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GZD2_k127_2754311_3	1242864.D187_001151	1.689e-75	265.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GZD2_k127_2754311_1	926569.ANT_08060	2.052e-134	437.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GZD2_k127_2754311_6	1173026.Glo7428_1028	6.561e-30	119.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GZD2_k127_2767705_3	926569.ANT_02910	9.376e-61	214.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
GZD2_k127_2767705_0	926569.ANT_02900	1.411e-79	275.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GZD2_k127_2767705_1	926569.ANT_02220	9.499e-74	251.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
GZD2_k127_2767705_2	926569.ANT_02220	1.897e-62	216.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
GZD2_k127_2767705_4	926569.ANT_02230	2.301e-13	72.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GZD2_k127_2782331_0	1232410.KI421424_gene1692	3.884e-64	237.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,43V05@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF-1	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
GZD2_k127_2782331_1	926569.ANT_28800	2.199e-46	170.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD2_k127_2784302_4	1158756.AQXQ01000004_gene455	3.079e-06	51.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S assembly protein IscX	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
GZD2_k127_2784302_0	525904.Tter_0560	5.171e-198	628.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GZD2_k127_2784302_2	926569.ANT_18250	1.059e-16	87.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_34
GZD2_k127_2784302_3	1121927.GOHSU_04_00230	3.259e-13	71.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4GF7U@85026|Gordoniaceae	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
GZD2_k127_2784302_1	926550.CLDAP_02830	3.042e-51	184.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GZD2_k127_2805523_0	926569.ANT_30100	3.989e-85	302.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
GZD2_k127_2805523_1	926569.ANT_31550	2.604e-07	52.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GZD2_k127_2811672_2	926569.ANT_03760	1.376e-11	66.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GZD2_k127_2811672_1	926569.ANT_20440	2.827e-12	75.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2811672_0	926569.ANT_20430	3.786e-70	242.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GZD2_k127_2839968_1	867845.KI911784_gene1094	4.905e-116	405.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HisKA_7TM,PAS_4,PAS_8
GZD2_k127_2839968_0	926550.CLDAP_31520	8.596e-153	494.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GZD2_k127_2839968_4	693661.Arcve_0215	4.255e-37	151.0	COG0109@1|root,arCOG00479@2157|Archaea,2XUEM@28890|Euryarchaeota,247C6@183980|Archaeoglobi	183980|Archaeoglobi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
GZD2_k127_2839968_6	1157490.EL26_00030	1.139e-09	66.0	COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HMWN@91061|Bacilli,278HM@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GZD2_k127_2839968_2	765420.OSCT_0044	2.324e-100	339.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,37723@32061|Chloroflexia	32061|Chloroflexia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_2839968_3	765420.OSCT_0043	1.727e-46	185.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GZD2_k127_2839968_5	926550.CLDAP_07700	1.797e-31	126.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_2844421_9	204669.Acid345_3656	1.426e-15	78.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GZD2_k127_2844421_7	1123075.AUDP01000031_gene2120	6.991e-57	208.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,3WNWP@541000|Ruminococcaceae	186801|Clostridia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GZD2_k127_2844421_3	926569.ANT_08150	3.068e-127	415.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_2844421_2	926569.ANT_08160	2.061e-128	422.0	COG0842@1|root,COG0842@2|Bacteria,2G774@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_2844421_1	926569.ANT_08170	1.429e-135	443.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_2844421_11	316055.RPE_0831	1.612e-05	55.0	COG3303@1|root,COG3303@2|Bacteria,1QXZC@1224|Proteobacteria,2TRV1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
GZD2_k127_2844421_5	357808.RoseRS_2229	1.288e-71	266.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_2844421_4	926569.ANT_02380	1.524e-118	387.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GZD2_k127_2844421_0	926569.ANT_16230	1.065e-162	522.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
GZD2_k127_2844421_10	933262.AXAM01000009_gene1467	4.735e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MN86@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
GZD2_k127_2844421_6	926569.ANT_08950	8.911e-62	230.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
GZD2_k127_2849820_0	926569.ANT_28950	7.769e-205	646.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
GZD2_k127_2849820_3	262316.MAP_0519c	5.03e-26	112.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,239MD@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_2849820_2	247490.KSU1_C1143	3.839e-71	246.0	COG1943@1|root,COG1943@2|Bacteria,2J0GJ@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GZD2_k127_2849820_1	926569.ANT_15470	4.033e-85	289.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi	200795|Chloroflexi	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GZD2_k127_2854170_1	926569.ANT_09310	2.206e-22	97.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_2854170_0	926569.ANT_09320	2.327e-122	407.0	COG5002@1|root,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_2854170_2	926569.ANT_09340	3.803e-18	90.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_2861148_0	1033810.HLPCO_000770	6.948e-172	552.0	COG0405@1|root,COG0405@2|Bacteria,2NQK8@2323|unclassified Bacteria	2|Bacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GZD2_k127_286666_4	1267535.KB906767_gene584	3.056e-30	126.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria,2JHVP@204432|Acidobacteriia	204432|Acidobacteriia	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GZD2_k127_286666_0	204669.Acid345_2974	1.339e-78	275.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
GZD2_k127_286666_1	867903.ThesuDRAFT_01219	1.092e-70	253.0	COG0226@1|root,COG0226@2|Bacteria,1UFGH@1239|Firmicutes,24D85@186801|Clostridia,3WDS1@538999|Clostridiales incertae sedis	186801|Clostridia	P	TIGRFAM phosphate ABC transporter, phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
GZD2_k127_286666_2	56780.SYN_00054	1.618e-49	180.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria,2MS9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GZD2_k127_286666_3	383372.Rcas_4092	6.807e-42	164.0	COG1262@1|root,COG1262@2|Bacteria,2GACQ@200795|Chloroflexi,375EB@32061|Chloroflexia	32061|Chloroflexia	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
GZD2_k127_286666_5	523845.AQXV01000048_gene611	5.543e-06	51.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,23QJ2@183939|Methanococci	183939|Methanococci	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
GZD2_k127_2871773_1	1211844.CBLM010000035_gene3337	9.569e-43	175.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,3VPYK@526524|Erysipelotrichia	526524|Erysipelotrichia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_2871773_0	1403819.BATR01000022_gene806	5.524e-175	582.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
GZD2_k127_2872277_2	398512.JQKC01000014_gene1567	7.673e-06	59.0	COG1208@1|root,COG3291@1|root,COG1208@2|Bacteria,COG3291@2|Bacteria,1TS8A@1239|Firmicutes,247MC@186801|Clostridia,3WGB2@541000|Ruminococcaceae	186801|Clostridia	JM	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GZD2_k127_2872277_0	926569.ANT_10660	0.0	1228.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GZD2_k127_2872277_3	1120958.AULD01000012_gene1514	5.127e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FMW7@85023|Microbacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GZD2_k127_2872277_4	1288083.AUKR01000009_gene1877	7.439e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GZD2_k127_2872277_1	926569.ANT_14010	6.409e-90	301.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GZD2_k127_2874156_0	1380347.JNII01000008_gene4407	5.465e-137	446.0	COG2909@1|root,COG2909@2|Bacteria,2IBFJ@201174|Actinobacteria,4EX5E@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,Pkinase
GZD2_k127_2874156_4	1273538.G159_04945	3.205e-55	204.0	2950P@1|root,2ZYQG@2|Bacteria,1V5HG@1239|Firmicutes,4HI30@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2874156_3	1121377.KB906417_gene3860	9.138e-80	272.0	COG5395@1|root,COG5395@2|Bacteria	2|Bacteria	T	membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
GZD2_k127_2874156_1	1220534.B655_1325	2.34e-119	391.0	COG0604@1|root,arCOG01458@2157|Archaea,2XURG@28890|Euryarchaeota	28890|Euryarchaeota	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GZD2_k127_2874156_6	329726.AM1_6084	2.166e-24	104.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2874156_2	1254432.SCE1572_40570	9.604e-115	374.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GZD2_k127_2874156_5	1286106.MPL1_02313	2.033e-52	189.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
GZD2_k127_2886558_9	163908.KB235896_gene2700	1.245e-17	85.0	COG2253@1|root,COG2253@2|Bacteria,1GBWG@1117|Cyanobacteria,1HQV5@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD2_k127_2886558_15	472759.Nhal_3749	1.064e-06	52.0	COG2253@1|root,COG2253@2|Bacteria,1NJT9@1224|Proteobacteria,1S0YI@1236|Gammaproteobacteria,1WXVW@135613|Chromatiales	135613|Chromatiales	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD2_k127_2886558_4	1463856.JOHY01000005_gene1984	1.645e-86	300.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD2_k127_2886558_3	1394178.AWOO02000088_gene963	4.659e-96	319.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHS4@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_2886558_6	1449063.JMLS01000004_gene2464	1.302e-55	201.0	COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,26V10@186822|Paenibacillaceae	91061|Bacilli	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GZD2_k127_2886558_5	28444.JODQ01000003_gene4977	1.433e-60	221.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4EIUK@85012|Streptosporangiales	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
GZD2_k127_2886558_7	1298858.AUEL01000005_gene1121	4.277e-41	154.0	COG0346@1|root,COG0346@2|Bacteria,1PKTJ@1224|Proteobacteria,2UZFD@28211|Alphaproteobacteria,43PU2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_2886558_2	649747.HMPREF0083_01246	2.508e-96	325.0	COG0657@1|root,COG0657@2|Bacteria,1TSMU@1239|Firmicutes,4HFBC@91061|Bacilli,2759Q@186822|Paenibacillaceae	91061|Bacilli	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
GZD2_k127_2886558_8	324602.Caur_2581	1.244e-33	134.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2886558_0	1120949.KB903329_gene9217	5.555e-247	791.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
GZD2_k127_2886558_10	1122609.AUGT01000013_gene4106	3.111e-16	81.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4DSW5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2886558_11	485913.Krac_3903	2.722e-14	80.0	2EACU@1|root,334GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_2886558_1	235985.BBPN01000022_gene2545	1.228e-99	330.0	COG1028@1|root,COG1028@2|Bacteria,2I01P@201174|Actinobacteria,2NIJ1@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_2886558_14	1116369.KB890024_gene4219	1.011e-06	57.0	2EK0M@1|root,33DR5@2|Bacteria,1NKNS@1224|Proteobacteria,2UNJZ@28211|Alphaproteobacteria,43P8N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GZD2_k127_2889380_3	1227453.C444_04392	7.044e-48	182.0	COG4221@1|root,arCOG01265@2157|Archaea,2XT0E@28890|Euryarchaeota,23U0H@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_2889380_0	383372.Rcas_3439	2.616e-278	878.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD2_k127_2889380_1	926569.ANT_15320	5.889e-150	486.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
GZD2_k127_2889380_4	926569.ANT_22500	2.076e-26	111.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GZD2_k127_2889380_2	335543.Sfum_1736	2.981e-120	393.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,43DN9@68525|delta/epsilon subdivisions,2X25J@28221|Deltaproteobacteria,2MS0P@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GZD2_k127_2896608_1	926569.ANT_17120	1.513e-180	571.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
GZD2_k127_2896608_2	665571.STHERM_c03260	1.825e-111	375.0	COG4214@1|root,COG4214@2|Bacteria,2J5AE@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
GZD2_k127_2896608_3	1304880.JAGB01000002_gene2129	5.84e-69	244.0	COG4223@1|root,COG4223@2|Bacteria,1TSFB@1239|Firmicutes,24BRS@186801|Clostridia	186801|Clostridia	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2896608_0	926569.ANT_24910	2.09e-227	713.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD2_k127_2896608_4	479435.Kfla_1928	2.486e-61	213.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DN4M@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_2903732_1	1382356.JQMP01000003_gene1423	3.817e-50	196.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_2903732_2	926569.ANT_08940	7.554e-27	119.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_2903732_0	926569.ANT_08950	2.597e-80	280.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
GZD2_k127_2914331_0	484770.UFO1_4171	1.032e-141	459.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4H3A2@909932|Negativicutes	909932|Negativicutes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GZD2_k127_2938122_1	395493.BegalDRAFT_3427	4.593e-85	288.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
GZD2_k127_2938122_0	666685.R2APBS1_1154	8.749e-200	635.0	COG3055@1|root,COG3055@2|Bacteria,1NHAC@1224|Proteobacteria,1RYBY@1236|Gammaproteobacteria,1XAGU@135614|Xanthomonadales	135614|Xanthomonadales	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2938122_2	525904.Tter_0136	2.551e-25	113.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_293870_1	580327.Tthe_2606	3.816e-118	389.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,42FRT@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_293870_5	1480694.DC28_07535	1.153e-17	88.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GZD2_k127_293870_4	485913.Krac_4389	9.812e-36	141.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K05558,ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
GZD2_k127_293870_6	1121904.ARBP01000008_gene3289	1.968e-16	91.0	COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
GZD2_k127_293870_0	1172188.KB911824_gene3406	4.666e-186	594.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria,4FG1N@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GZD2_k127_293870_2	1150398.JIBJ01000006_gene3692	1.77e-44	175.0	COG1409@1|root,COG3511@1|root,COG1409@2|Bacteria,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
GZD2_k127_293870_3	1382306.JNIM01000001_gene333	1.009e-36	151.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
GZD2_k127_293870_7	1410638.JHXJ01000026_gene1929	0.0004391	44.0	COG3049@1|root,COG3049@2|Bacteria,1TRTI@1239|Firmicutes,24AFG@186801|Clostridia,3WIKV@541000|Ruminococcaceae	186801|Clostridia	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT,CBAH
GZD2_k127_2945752_2	153721.MYP_430	1.091e-55	197.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
GZD2_k127_2945752_0	1173024.KI912152_gene819	1.366e-97	321.0	COG0262@1|root,COG0262@2|Bacteria,1GEAQ@1117|Cyanobacteria	1117|Cyanobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_2945752_1	574375.BAGA_29650	3.124e-75	257.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	yyaP	-	1.5.1.3	ko:K00287,ko:K03088	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RibD_C
GZD2_k127_2945752_3	1462527.CCDM010000002_gene1514	1.994e-54	197.0	COG0262@1|root,COG0262@2|Bacteria,1VE43@1239|Firmicutes,4HN5B@91061|Bacilli,23M00@182709|Oceanobacillus	91061|Bacilli	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_2947930_0	1121382.JQKG01000003_gene4233	1.771e-165	540.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26
GZD2_k127_2947930_1	660470.Theba_2293	1.06e-44	184.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,Glyco_hydro_2_N,Glyco_hydro_35
GZD2_k127_2954853_3	32049.SYNPCC7002_A1320	4.877e-12	66.0	COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1H067@1129|Synechococcus	1117|Cyanobacteria	P	chromate transport protein	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GZD2_k127_2954853_2	68170.KL590486_gene9693	2.286e-70	246.0	COG1277@1|root,COG1277@2|Bacteria,2IING@201174|Actinobacteria,4E5D6@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
GZD2_k127_2954853_1	1034769.KB910518_gene2025	1.653e-98	333.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HBXP@91061|Bacilli,26VNN@186822|Paenibacillaceae	91061|Bacilli	V	Bacitracin ABC transporter, ATP-binding protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_2954853_0	1538295.JY96_06170	6.423e-103	343.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VNXC@28216|Betaproteobacteria,1KMBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.148	ko:K07222,ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3,SnoaL_2
GZD2_k127_2958836_2	1968.JOEV01000027_gene4630	1.803e-25	110.0	COG2197@1|root,COG2197@2|Bacteria,2IEI9@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_2958836_0	1121324.CLIT_10c01870	2.92e-135	447.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GZD2_k127_2958836_1	649638.Trad_1432	1.999e-40	151.0	COG3093@1|root,COG3093@2|Bacteria,1WKRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG3093 Plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
GZD2_k127_2958836_4	1002367.HMPREF0673_02534	2.897e-06	49.0	COG2253@1|root,COG2253@2|Bacteria,4NPW4@976|Bacteroidetes,2FSGR@200643|Bacteroidia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD2_k127_2958836_3	370438.PTH_2692	1.733e-14	76.0	2E25X@1|root,32XCM@2|Bacteria,1UJJ7@1239|Firmicutes,25F48@186801|Clostridia,262ET@186807|Peptococcaceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD2_k127_2961164_1	926569.ANT_07600	2.39e-78	269.0	COG0483@1|root,COG0483@2|Bacteria,2G7NN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
GZD2_k127_2961164_0	926569.ANT_10620	7.421e-98	334.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
GZD2_k127_2961164_2	926569.ANT_18700	0.0003381	48.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GZD2_k127_2964174_0	326427.Cagg_2762	1.016e-140	453.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GZD2_k127_2964174_1	404380.Gbem_1627	1.59e-32	143.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
GZD2_k127_2964174_2	1120950.KB892799_gene2145	1.048e-07	61.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GZD2_k127_2966597_0	926569.ANT_08710	2.908e-91	306.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GZD2_k127_2966597_3	552811.Dehly_1103	2.135e-12	76.0	2EMMB@1|root,33F9Q@2|Bacteria,2G9IY@200795|Chloroflexi,34D9F@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_2966597_2	357808.RoseRS_3810	1.745e-34	140.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,375U2@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
GZD2_k127_2966597_1	926569.ANT_08730	9.425e-68	238.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
GZD2_k127_2972698_0	926569.ANT_13770	1.105e-268	835.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GZD2_k127_2972698_3	926569.ANT_13780	1.281e-93	315.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GZD2_k127_2972698_1	926569.ANT_13790	8.338e-248	771.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GZD2_k127_2972698_5	926569.ANT_13800	3.461e-47	173.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
GZD2_k127_2972698_2	926550.CLDAP_05030	8.287e-115	379.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
GZD2_k127_2972698_4	926569.ANT_13820	1.218e-77	265.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
GZD2_k127_2972698_7	565653.EGBG_00496	2.046e-10	72.0	COG1388@1|root,COG1705@1|root,COG3103@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,COG4991@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae	91061|Bacilli	MNU	defense response to other organism	-	-	-	ko:K02395,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM,SH3_3,SH3_8,SLAP
GZD2_k127_2972698_6	41431.PCC8801_1830	1.261e-45	181.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_2973055_3	614083.AWQR01000009_gene534	8.755e-31	121.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2VNI2@28216|Betaproteobacteria,4A9Y0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_2973055_2	614083.AWQR01000009_gene534	1.13e-33	132.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2VNI2@28216|Betaproteobacteria,4A9Y0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_2973055_1	485913.Krac_2116	1.556e-51	186.0	COG4702@1|root,COG4702@2|Bacteria	2|Bacteria	S	posttranslational protein targeting to endoplasmic reticulum membrane	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
GZD2_k127_2973055_0	649638.Trad_1486	8.304e-140	451.0	COG4214@1|root,COG4214@2|Bacteria,1WI4P@1297|Deinococcus-Thermus	2|Bacteria	G	PFAM Branched-chain amino acid transport system permease component	gguB	GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0019321,GO:0031224,GO:0042732,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
GZD2_k127_299851_1	926569.ANT_18970	2.024e-99	329.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GZD2_k127_299851_3	926569.ANT_18960	1.632e-48	181.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GZD2_k127_299851_2	926569.ANT_18950	1.833e-49	179.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GZD2_k127_299851_0	1278073.MYSTI_05406	9.032e-102	353.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
GZD2_k127_299851_4	326424.FRAAL0854	2.213e-34	143.0	COG5078@1|root,COG5078@2|Bacteria	2|Bacteria	O	protein modification by small protein conjugation	-	-	-	-	-	-	-	-	-	-	-	-	ThiF,UQ_con,Yop-YscD_cpl
GZD2_k127_299851_6	326424.FRAAL0857	6.285e-22	100.0	2EFHE@1|root,3399Z@2|Bacteria	2|Bacteria	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
GZD2_k127_299851_5	530564.Psta_4147	1.344e-24	111.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
GZD2_k127_3004_1	926569.ANT_30000	3.395e-144	470.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
GZD2_k127_3004_3	765420.OSCT_2297	3.464e-10	63.0	2A426@1|root,30SKW@2|Bacteria,2GAFI@200795|Chloroflexi,375XZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3004_4	1210884.HG799474_gene15133	8.486e-10	70.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
GZD2_k127_3004_0	926569.ANT_04920	1.202e-159	509.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_3004_2	926692.AZYG01000096_gene1895	7.241e-42	161.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,3WAP6@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
GZD2_k127_3004951_0	1071679.BG57_05395	3.565e-111	370.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2W1S8@28216|Betaproteobacteria,1K5IY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
GZD2_k127_3004951_1	1121918.ARWE01000001_gene495	3.271e-71	247.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
GZD2_k127_3004951_2	211165.AJLN01000116_gene3204	1.496e-62	222.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GZD2_k127_3005126_0	926569.ANT_06600	0.0	1072.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GZD2_k127_3005126_2	926569.ANT_06610	2.771e-48	176.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD2_k127_3005126_1	926569.ANT_06620	8.749e-84	285.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_3005126_3	1304880.JAGB01000001_gene677	4.349e-19	89.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
GZD2_k127_3037416_6	1231377.C426_2151	2.252e-46	173.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1YBYN@1357|Lactococcus	91061|Bacilli	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GZD2_k127_3037416_0	1343740.M271_05025	1.428e-160	539.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
GZD2_k127_3037416_2	1352941.M877_37410	5.269e-89	325.0	COG0446@1|root,COG0446@2|Bacteria,2GKQN@201174|Actinobacteria	201174|Actinobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GZD2_k127_3037416_4	1380763.BG53_09905	4.138e-76	263.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,26UHQ@186822|Paenibacillaceae	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_3037416_1	1500301.JQMF01000008_gene1002	1.155e-126	413.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,4B889@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GZD2_k127_3037416_3	246194.CHY_1258	3.214e-81	287.0	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,24AJF@186801|Clostridia,42G57@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM type III effector Hrp-dependent outers	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
GZD2_k127_3037416_5	1123320.KB889563_gene6419	6.264e-51	188.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
GZD2_k127_3039158_1	351627.Csac_1223	1.207e-80	284.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD2_k127_3039158_2	1123278.KB893617_gene3391	6.712e-18	93.0	2E9WF@1|root,33426@2|Bacteria,4P894@976|Bacteroidetes,47WZZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3039158_0	926569.ANT_23480	0.0	1146.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
GZD2_k127_3046395_3	926550.CLDAP_40610	4.99e-07	52.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GZD2_k127_3046395_2	555079.Toce_0184	1.553e-23	104.0	2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,24RY3@186801|Clostridia	186801|Clostridia	S	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
GZD2_k127_3046395_1	159087.Daro_2280	1.64e-70	252.0	COG4063@1|root,COG4063@2|Bacteria	2|Bacteria	H	Domain of unknown function (DUF4346)	-	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4346,MtrA
GZD2_k127_3046395_0	555079.Toce_0185	9.208e-101	338.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia	186801|Clostridia	P	Arsenite-activated ATPase (ArsA)	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GZD2_k127_3069934_2	937777.Deipe_0063	2.544e-49	187.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
GZD2_k127_3069934_1	1033734.CAET01000005_gene3750	9.067e-74	253.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4HH1R@91061|Bacilli,1ZICD@1386|Bacillus	91061|Bacilli	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GZD2_k127_3069934_0	330214.NIDE3489	5.833e-88	302.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
GZD2_k127_3069934_4	324602.Caur_1959	7.442e-47	171.0	2E3MN@1|root,33PAQ@2|Bacteria,2G91W@200795|Chloroflexi,377MD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3069934_6	324602.Caur_1958	4.262e-39	149.0	2E3MN@1|root,302XP@2|Bacteria,2G95X@200795|Chloroflexi,377TT@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3069934_5	1172179.AUKV01000009_gene4532	1.793e-40	155.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
GZD2_k127_3069934_3	479434.Sthe_3401	1.451e-47	175.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_3125894_6	521045.Kole_0125	2.756e-70	241.0	COG1126@1|root,COG1126@2|Bacteria,2GC18@200918|Thermotogae	200918|Thermotogae	E	PFAM ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
GZD2_k127_3125894_7	383372.Rcas_2181	8.316e-63	222.0	COG0765@1|root,COG0765@2|Bacteria,2G6U7@200795|Chloroflexi,376XG@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
GZD2_k127_3125894_11	315730.BcerKBAB4_2261	2.258e-29	120.0	2DNMG@1|root,32Y46@2|Bacteria,1VK1T@1239|Firmicutes,4HNYW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3125894_1	926569.ANT_14260	1.989e-144	464.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi	200795|Chloroflexi	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GZD2_k127_3125894_0	926569.ANT_14270	8.143e-172	544.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD2_k127_3125894_3	1128421.JAGA01000003_gene2788	4.384e-98	335.0	COG0508@1|root,COG0508@2|Bacteria,2NNYD@2323|unclassified Bacteria	2|Bacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD2_k127_3125894_9	1380391.JIAS01000013_gene3688	2.554e-37	148.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GZD2_k127_3125894_10	1223410.KN050846_gene2112	3.841e-32	142.0	COG2815@1|root,COG2815@2|Bacteria,4NXFG@976|Bacteroidetes,1I6HM@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	TIR_2
GZD2_k127_3125894_4	1173027.Mic7113_1368	1.202e-82	308.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,SpoIIE,TIR_2,WD40
GZD2_k127_3125894_5	221288.JH992901_gene4311	4.844e-80	274.0	COG2227@1|root,COG2227@2|Bacteria,1GQZP@1117|Cyanobacteria,1JKUR@1189|Stigonemataceae	1117|Cyanobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_3125894_2	926569.ANT_12760	1.284e-134	434.0	COG0421@1|root,COG0421@2|Bacteria,2G7ED@200795|Chloroflexi	200795|Chloroflexi	E	Spermidine synthase tetramerisation domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
GZD2_k127_3125894_8	926569.ANT_12780	6.474e-50	180.0	COG1586@1|root,COG1586@2|Bacteria,2G7DW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GZD2_k127_3126383_2	479432.Sros_4960	1.584e-11	69.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
GZD2_k127_3126383_0	670487.Ocepr_0734	4.158e-35	143.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
GZD2_k127_3126383_1	33876.JNXY01000032_gene3189	1.355e-34	143.0	COG2267@1|root,COG2267@2|Bacteria,2HV5I@201174|Actinobacteria,4DGQT@85008|Micromonosporales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_3140147_1	234267.Acid_0498	1.073e-156	499.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD2_k127_3140147_2	472759.Nhal_2611	1.281e-59	213.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X2EW@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GZD2_k127_3140147_3	1128421.JAGA01000003_gene2880	9.522e-12	69.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
GZD2_k127_3140147_0	1173023.KE650771_gene2604	7.484e-293	907.0	COG0028@1|root,COG0028@2|Bacteria,1G0KQ@1117|Cyanobacteria,1JJ9X@1189|Stigonemataceae	1117|Cyanobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GZD2_k127_3148910_0	926569.ANT_14670	3.455e-175	563.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GZD2_k127_3148910_1	485913.Krac_5203	5.113e-64	226.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
GZD2_k127_3148910_3	395961.Cyan7425_3707	5.312e-32	127.0	2EHSB@1|root,33BI2@2|Bacteria	2|Bacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
GZD2_k127_3148910_2	1197906.CAJQ02000047_gene4077	2.804e-36	139.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3150783_0	1122221.JHVI01000014_gene1367	5.931e-155	503.0	COG0665@1|root,COG0665@2|Bacteria,1WI96@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GZD2_k127_3150783_2	485913.Krac_9920	2.24e-18	87.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GZD2_k127_3150783_3	383372.Rcas_3109	4.234e-16	89.0	291JP@1|root,2ZP62@2|Bacteria,2GASU@200795|Chloroflexi,3778Y@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3150783_1	383372.Rcas_3108	5.989e-62	216.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,376EB@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GZD2_k127_315221_0	1049564.TevJSym_ac01750	5.353e-139	448.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
GZD2_k127_315221_3	118173.KB235914_gene4100	2.52e-11	67.0	COG3675@1|root,COG3675@2|Bacteria,1G7WY@1117|Cyanobacteria,1HD7F@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Lipase, class 3	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
GZD2_k127_315221_1	118173.KB235914_gene4100	1.285e-36	145.0	COG3675@1|root,COG3675@2|Bacteria,1G7WY@1117|Cyanobacteria,1HD7F@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Lipase, class 3	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
GZD2_k127_315221_2	946483.Cenrod_0250	6.792e-14	83.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GZD2_k127_3152413_0	926569.ANT_20720	7.794e-151	481.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
GZD2_k127_3152413_1	926569.ANT_11020	2.115e-132	435.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
GZD2_k127_3152413_2	926561.KB900617_gene2286	6.886e-22	101.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,247KG@186801|Clostridia,3WAB7@53433|Halanaerobiales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
GZD2_k127_3197115_0	1038858.AXBA01000006_gene838	6.979e-122	406.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,3EXW9@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
GZD2_k127_3197115_3	1089550.ATTH01000002_gene44	4.379e-10	68.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
GZD2_k127_3197115_1	1144275.COCOR_07205	2.482e-73	262.0	COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria,42S0W@68525|delta/epsilon subdivisions,2WVDD@28221|Deltaproteobacteria,2YU0R@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GZD2_k127_3197115_2	118161.KB235922_gene566	2.23e-44	166.0	COG1755@1|root,COG1755@2|Bacteria,1GDC2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
GZD2_k127_3222792_0	1173022.Cri9333_0822	6.657e-30	134.0	COG0793@1|root,COG0793@2|Bacteria,1G1XG@1117|Cyanobacteria,1H97P@1150|Oscillatoriales	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GZD2_k127_3222792_1	926550.CLDAP_23770	8.778e-26	120.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_3227860_4	485913.Krac_4856	4.524e-34	132.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_3227860_3	1459636.NTE_02190	7.644e-37	144.0	COG5649@1|root,2N58B@2157|Archaea	2157|Archaea	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GZD2_k127_3227860_1	485913.Krac_0875	2.713e-74	254.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_3227860_2	375451.RD1_2687	1.539e-40	160.0	COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GZD2_k127_3227860_0	1068980.ARVW01000001_gene4474	2.13e-94	316.0	COG2267@1|root,COG2267@2|Bacteria,2I5HD@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_3227860_5	485913.Krac_4435	3.187e-19	87.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_3244476_6	1027273.GZ77_03410	9.121e-52	189.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XJM0@135619|Oceanospirillales	135619|Oceanospirillales	C	Molybdenum cofactor sulfurase	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GZD2_k127_3244476_0	926569.ANT_14290	4.402e-200	650.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
GZD2_k127_3244476_7	926569.ANT_18430	3.482e-35	136.0	COG1872@1|root,COG1872@2|Bacteria,2G7H4@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GZD2_k127_3244476_9	1150474.JQJI01000005_gene294	4.765e-08	57.0	COG0762@1|root,COG0762@2|Bacteria,2GDIQ@200918|Thermotogae	200918|Thermotogae	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GZD2_k127_3244476_4	926569.ANT_18450	2.066e-76	264.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi	200795|Chloroflexi	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GZD2_k127_3244476_5	926569.ANT_18460	3.823e-75	260.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GZD2_k127_3244476_3	926569.ANT_18470	2.422e-80	279.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GZD2_k127_3244476_1	926569.ANT_18490	3.969e-93	311.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GZD2_k127_3244476_2	926569.ANT_18500	4.82e-92	315.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GZD2_k127_3244476_8	760117.JN27_17535	1.372e-09	65.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,473QK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Serine hydrolase (FSH1)	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GZD2_k127_3244743_1	935948.KE386495_gene1232	6.856e-91	305.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,42IG4@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GZD2_k127_3244743_2	1128421.JAGA01000002_gene343	1.175e-64	251.0	COG1744@1|root,COG1744@2|Bacteria	2|Bacteria	ET	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GZD2_k127_3244743_4	1120934.KB894403_gene289	1.017e-15	92.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,2I3FC@201174|Actinobacteria,4EFCV@85010|Pseudonocardiales	201174|Actinobacteria	Q	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
GZD2_k127_3244743_0	159087.Daro_3007	2.656e-160	517.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,2KVP2@206389|Rhodocyclales	206389|Rhodocyclales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
GZD2_k127_3244743_3	1476583.DEIPH_ctg064orf0008	5.556e-63	224.0	COG4805@1|root,COG4805@2|Bacteria,1WM4J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3248668_2	926569.ANT_12130	5.584e-90	297.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi	200795|Chloroflexi	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GZD2_k127_3248668_1	926569.ANT_12120	5.644e-102	344.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
GZD2_k127_3248668_0	926569.ANT_25740	2.08e-133	450.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
GZD2_k127_3260206_3	926569.ANT_23140	4.786e-34	135.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_3260206_0	926550.CLDAP_08640	7.797e-115	382.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
GZD2_k127_3260206_4	945713.IALB_1682	6.058e-06	51.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
GZD2_k127_3260206_1	349161.Dred_0160	4.289e-105	351.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GZD2_k127_3260206_2	326427.Cagg_1104	3.362e-53	199.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GZD2_k127_3265543_1	926569.ANT_13870	2.239e-36	141.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GZD2_k127_3265543_2	926569.ANT_13880	5.738e-18	87.0	2EU69@1|root,33MNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3265543_3	883126.HMPREF9710_04626	2.716e-17	94.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2VNYQ@28216|Betaproteobacteria,475KV@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
GZD2_k127_3265543_0	926569.ANT_13890	3.336e-59	207.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3274209_1	926564.KI911760_gene4963	4.151e-21	94.0	2C3CF@1|root,32RRR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
GZD2_k127_3274209_2	648996.Theam_1028	7.226e-09	61.0	28I8V@1|root,2Z8BN@2|Bacteria,2G4EN@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3274209_0	56780.SYN_00532	5.648e-188	595.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2MQAM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GZD2_k127_3281204_0	357808.RoseRS_3212	7.2e-89	299.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
GZD2_k127_3281204_2	484770.UFO1_1184	3.183e-27	124.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,1UZZ7@1239|Firmicutes,4H3PK@909932|Negativicutes	909932|Negativicutes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
GZD2_k127_3281204_1	234267.Acid_3657	4.277e-80	273.0	COG0855@1|root,COG0855@2|Bacteria,3Y2YI@57723|Acidobacteria	57723|Acidobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GZD2_k127_3286007_0	1499967.BAYZ01000052_gene4665	2.897e-165	561.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
GZD2_k127_3286007_9	1123371.ATXH01000007_gene534	2.199e-46	175.0	COG0566@1|root,COG0566@2|Bacteria,2GHKT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
GZD2_k127_3286007_12	479434.Sthe_2462	8.598e-12	71.0	COG0457@1|root,COG0457@2|Bacteria	479434.Sthe_2462|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3286007_11	153721.MYP_2922	2.529e-31	128.0	COG0824@1|root,COG0824@2|Bacteria,4NS45@976|Bacteroidetes,47RIG@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GZD2_k127_3286007_4	926569.ANT_05870	5.976e-57	205.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
GZD2_k127_3286007_1	1449063.JMLS01000011_gene289	1.51e-139	458.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,26QTC@186822|Paenibacillaceae	91061|Bacilli	S	Peptidase dimerisation domain	-	-	-	ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_3286007_13	59374.Fisuc_1628	2.576e-10	72.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_3286007_6	926569.ANT_16940	8.655e-53	202.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_3286007_5	864069.MicloDRAFT_00046540	2.255e-55	198.0	COG2323@1|root,COG2323@2|Bacteria,1PKVB@1224|Proteobacteria,2UZH7@28211|Alphaproteobacteria,1JUD7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
GZD2_k127_3286007_7	485913.Krac_10690	2.929e-52	201.0	29BBV@1|root,2ZCHD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GZD2_k127_3286007_2	56780.SYN_02058	1.821e-103	356.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
GZD2_k127_3286007_3	525897.Dbac_1160	4.567e-60	220.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2M8ZX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GZD2_k127_3286007_10	1121378.KB899751_gene3527	1.662e-31	133.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yflN_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_3286007_8	1547445.LO80_04355	1.028e-50	184.0	COG3153@1|root,COG3153@2|Bacteria,1QU4W@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_3290994_7	1267535.KB906767_gene4349	3.242e-27	125.0	COG1807@1|root,COG1807@2|Bacteria,3Y46U@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3290994_10	258594.RPA3526	4.85e-05	55.0	2ESUM@1|root,33KD1@2|Bacteria	2|Bacteria	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
GZD2_k127_3290994_5	1254432.SCE1572_05510	2.547e-37	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_3290994_4	1382356.JQMP01000003_gene1897	1.2e-47	177.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GZD2_k127_3290994_8	388399.SSE37_06114	4.279e-23	103.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3290994_3	926569.ANT_08670	3.762e-50	185.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GZD2_k127_3290994_6	926569.ANT_08660	2.822e-34	134.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GZD2_k127_3290994_1	1191523.MROS_0720	4.12e-73	257.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	CP_1064	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_3290994_2	1541065.JRFE01000029_gene3524	1.421e-54	199.0	COG0637@1|root,COG0637@2|Bacteria,1GI36@1117|Cyanobacteria,3VMPN@52604|Pleurocapsales	1117|Cyanobacteria	S	HAD-hyrolase-like	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
GZD2_k127_3290994_0	926569.ANT_18710	2.568e-74	252.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GZD2_k127_3290994_9	926569.ANT_18700	1.242e-14	79.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GZD2_k127_3291619_3	530564.Psta_3376	2.747e-31	128.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GZD2_k127_3291619_2	1476583.DEIPH_ctg011orf0144	1.326e-134	441.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD2_k127_3291619_1	221288.JH992901_gene4589	5.936e-160	518.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria,1JHCD@1189|Stigonemataceae	1117|Cyanobacteria	IM	pfkB family carbohydrate kinase	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
GZD2_k127_3291619_0	221288.JH992901_gene4586	3.178e-220	698.0	COG0279@1|root,COG0438@1|root,COG0279@2|Bacteria,COG0438@2|Bacteria,1G1I9@1117|Cyanobacteria,1JHY0@1189|Stigonemataceae	1117|Cyanobacteria	GM	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_4,Glycos_transf_1,SIS_2
GZD2_k127_3292958_2	105559.Nwat_1360	5.301e-81	287.0	COG3852@1|root,COG4251@1|root,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,1WYC4@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
GZD2_k127_3292958_1	485913.Krac_10180	4.947e-87	296.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
GZD2_k127_3292958_3	304371.MCP_0795	1.756e-66	232.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GZD2_k127_3292958_4	926550.CLDAP_09500	7.561e-55	197.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD2_k127_3292958_0	765420.OSCT_2276	9.246e-119	390.0	COG1092@1|root,COG1092@2|Bacteria,2G7Y9@200795|Chloroflexi,3767A@32061|Chloroflexia	32061|Chloroflexia	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GZD2_k127_3293382_1	1379698.RBG1_1C00001G0857	4.658e-41	157.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3293382_2	926569.ANT_19350	2.765e-40	163.0	COG0642@1|root,COG3283@1|root,COG2205@2|Bacteria,COG3283@2|Bacteria	2|Bacteria	EK	Transcriptional regulator of aromatic amino acids metabolism	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	ANTAR,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,LytTR,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_3293382_0	479434.Sthe_1941	1.461e-54	199.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3293382_3	861299.J421_0531	2.754e-20	91.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
GZD2_k127_3294525_1	526227.Mesil_2489	7.547e-109	378.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GZD2_k127_3294525_0	926550.CLDAP_14400	4.003e-227	716.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
GZD2_k127_3295507_0	1122962.AULH01000014_gene900	1.928e-131	430.0	COG1653@1|root,COG1653@2|Bacteria,1R6PD@1224|Proteobacteria,2U3EP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
GZD2_k127_3295507_2	926550.CLDAP_17910	1.645e-99	334.0	COG1609@1|root,COG1609@2|Bacteria,2G7NI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI
GZD2_k127_3295507_1	1205680.CAKO01000003_gene3681	1.849e-124	407.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GZD2_k127_3295507_3	351627.Csac_1340	1.042e-80	272.0	COG3669@1|root,COG3669@2|Bacteria,1TT4V@1239|Firmicutes,24A0S@186801|Clostridia,42HWC@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase family 29 (alpha-L-fucosidase)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
GZD2_k127_3297481_1	903818.KI912268_gene2018	1.612e-76	264.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GZD2_k127_3297481_0	926569.ANT_27540	2.915e-113	376.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
GZD2_k127_3297481_5	1211114.ALIP01000140_gene2317	4.603e-29	120.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,1ST3I@1236|Gammaproteobacteria,1X8AD@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3297481_2	926569.ANT_27550	2.754e-76	262.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
GZD2_k127_3297481_3	926569.ANT_04570	1.918e-68	236.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
GZD2_k127_3297481_4	1382306.JNIM01000001_gene441	1.563e-41	155.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GZD2_k127_3298433_4	329726.AM1_2638	2.9e-06	58.0	COG1716@1|root,COG1716@2|Bacteria,1FZW5@1117|Cyanobacteria	2|Bacteria	T	PFAM FHA domain	fraH	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
GZD2_k127_3298433_5	1242864.D187_008786	3.879e-06	57.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
GZD2_k127_3298433_2	243231.GSU0942	2.408e-75	261.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
GZD2_k127_3298433_0	1120746.CCNL01000008_gene809	1.059e-96	333.0	COG0371@1|root,COG0371@2|Bacteria	2|Bacteria	C	Dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
GZD2_k127_3298433_1	926569.ANT_11860	2.251e-90	304.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
GZD2_k127_3298433_3	1382306.JNIM01000001_gene1705	3.791e-19	90.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD2_k127_3305853_0	926569.ANT_29100	1.706e-56	202.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi	200795|Chloroflexi	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
GZD2_k127_3305853_2	926550.CLDAP_39910	2.161e-08	57.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi	200795|Chloroflexi	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
GZD2_k127_3305853_1	511051.CSE_14320	1.602e-16	88.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
GZD2_k127_3322025_2	240015.ACP_0319	1.733e-58	205.0	COG0667@1|root,COG0667@2|Bacteria,3Y35T@57723|Acidobacteria,2JK73@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_3322025_0	926569.ANT_03150	6.611e-114	377.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GZD2_k127_3322025_1	1128421.JAGA01000002_gene1310	1.065e-91	309.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_3325233_4	926569.ANT_19690	1.736e-48	175.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_3325233_3	926569.ANT_19700	1.714e-51	191.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD2_k127_3325233_2	42256.RradSPS_0129	1.055e-61	218.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
GZD2_k127_3325233_0	926569.ANT_19710	3.813e-86	289.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GZD2_k127_3325233_1	926569.ANT_22980	4.92e-63	223.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_3338123_4	1293054.HSACCH_02575	2.613e-51	192.0	COG2267@1|root,COG2267@2|Bacteria,1V5SG@1239|Firmicutes,24D50@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_3338123_8	316274.Haur_0393	8.146e-07	58.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
GZD2_k127_3338123_1	926569.ANT_02760	1.69e-60	218.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD2_k127_3338123_2	1347369.CCAD010000065_gene3754	4.098e-53	198.0	COG0596@1|root,COG0596@2|Bacteria,1V0M4@1239|Firmicutes,4HPRJ@91061|Bacilli,1ZHQC@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_3338123_6	1206726.BAFV01000065_gene4502	1.505e-37	150.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria,4G0ZK@85025|Nocardiaceae	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3338123_0	1211817.CCAT010000009_gene866	8.642e-64	223.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,36I36@31979|Clostridiaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GZD2_k127_3338123_3	661478.OP10G_0321	2.887e-52	189.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_3338123_7	1321778.HMPREF1982_02364	5.474e-25	110.0	29UV3@1|root,316MX@2|Bacteria,1UH1R@1239|Firmicutes,24QZD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GZD2_k127_3345290_4	357808.RoseRS_0300	1.4e-42	161.0	COG1943@1|root,COG1943@2|Bacteria,2G88H@200795|Chloroflexi,377A5@32061|Chloroflexia	32061|Chloroflexia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3345290_2	926550.CLDAP_05410	3.517e-123	406.0	COG1167@1|root,COG1167@2|Bacteria,2G81Z@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD2_k127_3345290_5	1116232.AHBF01000093_gene7373	4.637e-40	158.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3345290_6	700598.Niako_5751	1.7e-37	145.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,1IT4P@117747|Sphingobacteriia	976|Bacteroidetes	K	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD2_k127_3345290_1	395494.Galf_2689	2.117e-141	461.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GZD2_k127_3345290_0	697282.Mettu_0616	1.311e-146	473.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
GZD2_k127_3345290_3	926569.ANT_23460	1.115e-76	261.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GZD2_k127_335386_1	717605.Theco_0114	4.253e-143	458.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,26VTM@186822|Paenibacillaceae	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GZD2_k127_335386_0	211114.JOEF01000025_gene185	2.774e-183	593.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_3354536_5	242159.ABO96031	1.178e-06	56.0	2AHTF@1|root,2S2PD@2759|Eukaryota,389P4@33090|Viridiplantae,34MIJ@3041|Chlorophyta	3041|Chlorophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3354536_1	926550.CLDAP_21010	9.646e-66	244.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD2_k127_3354536_0	926550.CLDAP_21020	1.345e-67	237.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_3354536_2	926569.ANT_28350	4.248e-29	119.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GZD2_k127_3354536_4	479434.Sthe_0704	7.278e-10	64.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi,27YG7@189775|Thermomicrobia	189775|Thermomicrobia	S	Stage V sporulation protein S (SpoVS)	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GZD2_k127_3354536_3	1184607.AUCHE_05_06170	6.749e-13	75.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4F709@85018|Dermatophilaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_3354536_6	391603.FBALC1_06663	9.764e-05	46.0	2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3357947_2	926569.ANT_02540	1.923e-25	107.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GZD2_k127_3357947_1	926569.ANT_02800	4.418e-117	386.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GZD2_k127_3357947_0	926569.ANT_02790	3.419e-193	627.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
GZD2_k127_3357958_1	13035.Dacsa_3315	2.772e-64	237.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
GZD2_k127_3357958_0	926569.ANT_03980	8.806e-119	392.0	COG0524@1|root,COG0524@2|Bacteria,2G6W1@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD2_k127_3357958_2	926569.ANT_03990	5.698e-48	175.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi	200795|Chloroflexi	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	lacD	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
GZD2_k127_3362042_0	926569.ANT_09800	1.289e-130	423.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GZD2_k127_3362042_2	926569.ANT_09790	1.98e-44	167.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GZD2_k127_3362042_1	1191523.MROS_0930	6.518e-110	366.0	COG0787@1|root,COG0787@2|Bacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
GZD2_k127_3362042_4	146922.JOFU01000004_gene7283	2.415e-23	105.0	COG0454@1|root,COG0456@2|Bacteria,2IHUH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD2_k127_3362042_3	497964.CfE428DRAFT_6673	7.71e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GZD2_k127_3362042_6	929556.Solca_1731	5.747e-15	79.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1ITUD@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GZD2_k127_3372420_3	926569.ANT_06250	1.836e-34	134.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
GZD2_k127_3372420_1	926569.ANT_00510	5.719e-88	299.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GZD2_k127_3372420_4	926569.ANT_00520	9.795e-34	136.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
GZD2_k127_3372420_0	926569.ANT_00530	1.425e-205	654.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
GZD2_k127_3372420_2	1313301.AUGC01000001_gene1573	2.454e-59	212.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_3386293_0	485913.Krac_9356	8.124e-155	497.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD2_k127_3386293_2	485913.Krac_9355	2.768e-129	418.0	COG0559@1|root,COG0559@2|Bacteria,2G93P@200795|Chloroflexi	200795|Chloroflexi	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
GZD2_k127_3386293_1	485913.Krac_9354	1.14e-133	434.0	COG4177@1|root,COG4177@2|Bacteria,2G8KF@200795|Chloroflexi	200795|Chloroflexi	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD2_k127_3386293_3	485913.Krac_9353	1.483e-112	368.0	COG0411@1|root,COG0411@2|Bacteria,2G8SH@200795|Chloroflexi	200795|Chloroflexi	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD2_k127_3386293_4	485913.Krac_9352	1.532e-98	327.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
GZD2_k127_3386293_5	8496.XP_006258169.1	1.649e-07	59.0	COG2159@1|root,KOG4245@2759|Eukaryota,38BZU@33154|Opisthokonta,3BAFS@33208|Metazoa,3CXVU@33213|Bilateria,484NQ@7711|Chordata,48Y8H@7742|Vertebrata	33208|Metazoa	S	decarboxylase	ACMSD	GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
GZD2_k127_3396191_1	886293.Sinac_1691	3.26e-173	555.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_3396191_16	886293.Sinac_2688	2.942e-18	93.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	2|Bacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_3396191_9	886293.Sinac_2689	3.054e-79	287.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
GZD2_k127_3396191_2	383372.Rcas_0452	9.724e-149	495.0	2BWCS@1|root,32QZE@2|Bacteria,2G818@200795|Chloroflexi,3763T@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3396191_11	926550.CLDAP_36160	2.198e-57	220.0	COG1807@1|root,COG1807@2|Bacteria,2G7UD@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3396191_12	383372.Rcas_0469	1.288e-53	207.0	COG1807@1|root,COG1807@2|Bacteria,2G7UD@200795|Chloroflexi,3768B@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3396191_15	765420.OSCT_1998	1.209e-21	109.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3396191_0	761193.Runsl_4744	1.609e-224	728.0	COG0383@1|root,COG0383@2|Bacteria,4NEC3@976|Bacteroidetes,47NE0@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Glyco_hydro_38,Glyco_hydro_38C
GZD2_k127_3396191_6	926550.CLDAP_36210	2.908e-102	342.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_3396191_7	926550.CLDAP_36200	8.843e-94	314.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GZD2_k127_3396191_10	272844.PAB0773	2.07e-70	245.0	COG0110@1|root,arCOG01848@2157|Archaea,2XWJM@28890|Euryarchaeota,242NY@183968|Thermococci	183968|Thermococci	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GZD2_k127_3396191_3	370438.PTH_0393	1.64e-137	447.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GZD2_k127_3396191_5	926569.ANT_20360	5.77e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GZD2_k127_3396191_4	926569.ANT_20380	1.718e-121	410.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi	2|Bacteria	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,DUF2325,GNVR,Wzz
GZD2_k127_3396191_8	926569.ANT_29320	1.213e-89	304.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
GZD2_k127_3396191_13	926569.ANT_13140	4.636e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_3396191_14	926569.ANT_13160	4.346e-41	164.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GZD2_k127_3398833_1	926569.ANT_22190	2.475e-25	121.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_3398833_2	926569.ANT_00760	3.268e-24	110.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_3398833_3	1123242.JH636434_gene3172	8.595e-06	58.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
GZD2_k127_3398833_0	313596.RB2501_12022	5.192e-38	157.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_3400174_3	926569.ANT_01660	4.452e-82	276.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
GZD2_k127_3400174_0	926569.ANT_01650	2.687e-158	504.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
GZD2_k127_3400174_1	525897.Dbac_0439	4.936e-157	510.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,43ADQ@68525|delta/epsilon subdivisions,2X5TK@28221|Deltaproteobacteria,2MAD4@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
GZD2_k127_3400174_7	926569.ANT_00080	1.109e-34	137.0	COG1725@1|root,COG1725@2|Bacteria,2G7C5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
GZD2_k127_3400174_2	926569.ANT_00090	3.273e-135	437.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	2|Bacteria	O	PFAM band 7 protein	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
GZD2_k127_3400174_6	192952.MM_0383	9.121e-49	182.0	COG5658@1|root,arCOG04484@2157|Archaea,2XVWE@28890|Euryarchaeota,2NB7Z@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
GZD2_k127_3400174_4	868131.MSWAN_0705	2.427e-66	235.0	arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD2_k127_3400174_5	1124780.ANNU01000036_gene60	1.388e-52	203.0	COG4745@1|root,COG4745@2|Bacteria,4P4EE@976|Bacteroidetes	976|Bacteroidetes	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3400174_8	1499967.BAYZ01000041_gene2381	1.921e-30	131.0	COG0642@1|root,COG2205@2|Bacteria	1499967.BAYZ01000041_gene2381|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_341059_1	485913.Krac_7099	4.223e-27	120.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
GZD2_k127_341059_3	658655.HMPREF0988_03165	0.000134	47.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27PAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GZD2_k127_341059_0	926569.ANT_08150	9.518e-108	358.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_341059_2	1121090.KB894696_gene43	0.0001036	52.0	COG0842@1|root,COG0842@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus	91061|Bacilli	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_341059_4	1347086.CCBA010000012_gene2030	0.0003638	46.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3415559_0	1379698.RBG1_1C00001G1471	6.129e-191	602.0	COG4799@1|root,COG4799@2|Bacteria,2NNWQ@2323|unclassified Bacteria	2|Bacteria	I	carboxyl transferase	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD2_k127_3415559_2	926569.ANT_00730	1.509e-80	293.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3415559_1	926550.CLDAP_21600	4.006e-95	323.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_3415559_3	383372.Rcas_3354	1.343e-08	60.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GZD2_k127_3416047_3	926569.ANT_05520	7.345e-14	72.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GZD2_k127_3416047_2	926569.ANT_05520	4.231e-37	143.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GZD2_k127_3416047_0	926569.ANT_05530	4.719e-129	421.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GZD2_k127_3416047_1	926569.ANT_25530	2.691e-41	160.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD2_k127_3418053_2	765420.OSCT_2371	8.03e-34	140.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3418053_0	118163.Ple7327_0472	2.321e-127	435.0	29N3X@1|root,3091P@2|Bacteria,1G154@1117|Cyanobacteria,3VM7V@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3418053_1	429009.Adeg_1620	2.607e-42	168.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,42G4W@68295|Thermoanaerobacterales	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD2_k127_3421136_3	926569.ANT_03940	1.898e-82	278.0	COG0538@1|root,COG0538@2|Bacteria,2G5SM@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
GZD2_k127_3421136_0	144197.XP_008279845.1	2.198e-144	466.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,490QX@7742|Vertebrata,49UJ7@7898|Actinopterygii	33208|Metazoa	F	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	CAD	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905	2.1.3.2,3.5.2.3,6.3.5.5	ko:K11540	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
GZD2_k127_3421136_4	272562.CA_C0464	2.796e-35	138.0	COG3323@1|root,COG3323@2|Bacteria,1VCAN@1239|Firmicutes,24K5S@186801|Clostridia,36JU4@31979|Clostridiaceae	186801|Clostridia	S	cog cog3323	-	-	-	-	-	-	-	-	-	-	-	-	CutA1
GZD2_k127_3421136_2	536227.CcarbDRAFT_5182	1.468e-100	338.0	COG0697@1|root,COG2371@1|root,COG0697@2|Bacteria,COG2371@2|Bacteria,1TPST@1239|Firmicutes,248K5@186801|Clostridia,36E35@31979|Clostridiaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_3421136_5	338966.Ppro_0940	1.141e-33	133.0	COG4316@1|root,COG4316@2|Bacteria,1RHXU@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2251
GZD2_k127_3421136_1	130081.XP_005704774.1	9.222e-128	416.0	COG0122@1|root,COG0458@1|root,KOG0370@2759|Eukaryota,KOG2875@2759|Eukaryota	2759|Eukaryota	L	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	URA2	GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141	2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5	ko:K01954,ko:K01955,ko:K03660,ko:K11540,ko:K11541,ko:K19656	ko00240,ko00250,ko01100,ko03410,map00240,map00250,map01100,map03410	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002,ko03036,ko03400	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,HhH-GPD,MGS,OGG_N,OTCace,OTCace_N
GZD2_k127_3422580_7	926569.ANT_10860	8.905e-71	239.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GZD2_k127_3422580_1	269797.Mbar_A1244	2.479e-171	549.0	COG0520@1|root,arCOG00065@2157|Archaea	2157|Archaea	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GZD2_k127_3422580_0	1386089.N865_11555	1.962e-199	632.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GZD2_k127_3422580_6	926569.ANT_02410	8.416e-86	295.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pelF	-	-	ko:K21011,ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
GZD2_k127_3422580_9	1111069.TCCBUS3UF1_8400	4.346e-34	136.0	COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
GZD2_k127_3422580_8	765420.OSCT_0663	4.361e-50	197.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3422580_3	926569.ANT_23150	1.339e-118	391.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_3422580_10	331635.G5S_0562	4.328e-05	51.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD2_k127_3422580_4	926550.CLDAP_18870	5.34e-99	353.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
GZD2_k127_3422580_2	1089550.ATTH01000001_gene2135	3.295e-146	479.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
GZD2_k127_3422580_5	649638.Trad_2634	1.414e-90	314.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
GZD2_k127_3424100_1	926550.CLDAP_24510	0.0006171	45.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
GZD2_k127_3424100_0	1521187.JPIM01000005_gene2268	1.213e-180	580.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1609@1|root,COG2207@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1609@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02529,ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,Cupin_2,HATPase_c,HTH_18,HisKA,Peripla_BP_3,Response_reg
GZD2_k127_3424434_4	351160.RCIX1898	8.489e-25	109.0	COG1668@1|root,arCOG04450@2157|Archaea,2XTRJ@28890|Euryarchaeota,2N9IA@224756|Methanomicrobia	224756|Methanomicrobia	C	COG1668 ABC-type Na efflux pump, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
GZD2_k127_3424434_0	1041930.Mtc_0796	5.621e-71	255.0	COG1668@1|root,arCOG01470@2157|Archaea,2XU06@28890|Euryarchaeota,2N9QX@224756|Methanomicrobia	224756|Methanomicrobia	C	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
GZD2_k127_3424434_2	675635.Psed_0414	3.287e-58	216.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
GZD2_k127_3424434_3	1041139.KB902624_gene5711	3.129e-57	203.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,4BF1Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	MA20_26530	-	1.17.2.1,1.3.99.16	ko:K07302,ko:K18029	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
GZD2_k127_3424434_1	1297863.APJF01000019_gene2411	9.301e-70	246.0	COG1529@1|root,COG2010@1|root,COG1529@2|Bacteria,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TVYT@28211|Alphaproteobacteria,3K6MK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	MA20_26525	-	1.17.2.1	ko:K18030	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C2,Cytochrom_C,Cytochrome_CBB3
GZD2_k127_3426226_1	926569.ANT_11800	2.561e-73	263.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_3426226_0	926569.ANT_11800	2.391e-83	298.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_3426226_3	926569.ANT_11800	2.971e-53	208.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_3426226_2	926569.ANT_11800	2.699e-69	250.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_3434098_4	479434.Sthe_2099	6.394e-45	174.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
GZD2_k127_3434098_2	269797.Mbar_A1533	2.681e-68	239.0	COG1926@1|root,arCOG00041@2157|Archaea,2XWHP@28890|Euryarchaeota,2N9V9@224756|Methanomicrobia	224756|Methanomicrobia	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
GZD2_k127_3434098_1	215803.DB30_2061	1.73e-134	439.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2
GZD2_k127_3434098_0	357808.RoseRS_3701	8.048e-148	478.0	COG0513@1|root,COG0513@2|Bacteria,2G7NJ@200795|Chloroflexi,377YZ@32061|Chloroflexia	32061|Chloroflexia	JKL	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
GZD2_k127_3434098_3	1366050.N234_05385	1.648e-66	237.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,2VPJH@28216|Betaproteobacteria,1K0I0@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_3436334_5	525904.Tter_1853	8.666e-23	109.0	COG0842@1|root,COG0842@2|Bacteria,2NPA6@2323|unclassified Bacteria	2|Bacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_3436334_2	1128421.JAGA01000002_gene314	3.319e-93	316.0	COG1131@1|root,COG1131@2|Bacteria,2NQPB@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_3436334_6	926569.ANT_07280	1.26e-05	52.0	2DCDY@1|root,2ZDSU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3436334_1	926569.ANT_07270	4.036e-95	315.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
GZD2_k127_3436334_0	926569.ANT_07260	2.275e-105	348.0	COG4820@1|root,COG4820@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,HSP70,MreB_Mbl,PilM_2
GZD2_k127_3436334_4	1304865.JAGF01000001_gene1142	1.109e-35	143.0	COG4766@1|root,COG4766@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	eutQ	-	-	ko:K04019,ko:K04030	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	Cupin_2,EutQ
GZD2_k127_3436334_3	926569.ANT_07230	1.106e-41	154.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
GZD2_k127_345738_7	266117.Rxyl_1792	6.137e-31	130.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GZD2_k127_345738_5	1157490.EL26_15890	1.552e-50	183.0	COG1051@1|root,COG1051@2|Bacteria,1V6D5@1239|Firmicutes,4HJTU@91061|Bacilli	91061|Bacilli	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_345738_1	926569.ANT_00920	5.861e-154	500.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_4,PAS_8,PAS_9
GZD2_k127_345738_9	1274.HX89_07615	1.614e-10	70.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,1ZVV0@145357|Dermacoccaceae	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD2_k127_345738_6	1128421.JAGA01000002_gene1694	1.356e-37	151.0	COG2176@1|root,COG2378@1|root,COG2176@2|Bacteria,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	dnaQ	-	2.7.7.7	ko:K02342,ko:K03763,ko:K13573	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03051,ko03400	-	-	-	GIY-YIG,RNase_T,VRR_NUC,WYL
GZD2_k127_345738_2	926569.ANT_30550	3.164e-75	259.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GZD2_k127_345738_0	926569.ANT_05370	2.483e-178	571.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GZD2_k127_345738_8	1382306.JNIM01000001_gene3668	1.275e-20	102.0	COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_345738_4	1267535.KB906767_gene4070	3.945e-71	252.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
GZD2_k127_3458085_3	1254432.SCE1572_05340	1.38e-05	49.0	COG1305@1|root,COG1305@2|Bacteria,1R9WH@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GZD2_k127_3458085_0	237368.SCABRO_02661	2.495e-228	716.0	COG1032@1|root,COG1032@2|Bacteria,2IXHH@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
GZD2_k127_3458085_1	1035308.AQYY01000001_gene1427	4.574e-186	595.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,263IN@186807|Peptococcaceae	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD2_k127_3458085_2	1304865.JAGF01000001_gene1436	1.19e-158	506.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_3458256_2	926569.ANT_08300	3.19e-86	289.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GZD2_k127_3458256_4	926569.ANT_08310	2.511e-50	184.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GZD2_k127_3458256_1	926569.ANT_08320	1.862e-189	599.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GZD2_k127_3458256_3	926569.ANT_08330	8.701e-64	222.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GZD2_k127_3458256_0	926569.ANT_08340	6.599e-197	622.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
GZD2_k127_3461742_1	926550.CLDAP_10700	2.982e-149	477.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
GZD2_k127_3461742_0	926550.CLDAP_10690	1.89e-165	531.0	COG3552@1|root,COG4372@1|root,COG3552@2|Bacteria,COG4372@2|Bacteria,2G60I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
GZD2_k127_3461742_2	1209984.BN978_02149	4.151e-43	163.0	COG1917@1|root,COG1917@2|Bacteria,2I43Q@201174|Actinobacteria,23AR9@1762|Mycobacteriaceae	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_3461742_4	927677.ALVU02000001_gene1921	1.944e-22	102.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1H580@1142|Synechocystis	1117|Cyanobacteria	T	Transcriptional regulatory protein, C terminal	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3461742_3	203119.Cthe_1805	4.404e-24	105.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD2_k127_3461742_5	1538295.JY96_06170	8.91e-19	87.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VNXC@28216|Betaproteobacteria,1KMBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.148	ko:K07222,ko:K18277	ko00680,map00680	-	R05623	RC00058	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3,SnoaL_2
GZD2_k127_3469344_3	671143.DAMO_1144	3.709e-55	197.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
GZD2_k127_3469344_2	926569.ANT_21080	9.758e-69	243.0	COG0555@1|root,COG0555@2|Bacteria,2GBHF@200795|Chloroflexi	200795|Chloroflexi	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
GZD2_k127_3469344_1	765420.OSCT_1869	2.565e-74	260.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,376S8@32061|Chloroflexia	32061|Chloroflexia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
GZD2_k127_3469344_5	926569.ANT_21070	5.343e-29	123.0	COG1695@1|root,COG1695@2|Bacteria,2G7I0@200795|Chloroflexi	200795|Chloroflexi	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GZD2_k127_3469344_0	292459.STH384	4.128e-101	337.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia	186801|Clostridia	H	PFAM extracellular solute-binding protein family 1	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
GZD2_k127_3469344_4	1121403.AUCV01000001_gene987	6.486e-54	199.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria,2MIXC@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
GZD2_k127_3475153_2	1219031.BBJR01000028_gene185	7.52e-06	52.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,4A9UZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	ompR	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3475153_1	926569.ANT_27990	2.493e-107	361.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926569.ANT_27990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3475153_0	1499967.BAYZ01000060_gene6002	3.632e-175	574.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
GZD2_k127_3476335_1	1128421.JAGA01000002_gene557	9.108e-159	506.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GZD2_k127_3476335_2	383372.Rcas_2295	1.258e-27	125.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
GZD2_k127_3476335_0	235985.BBPN01000040_gene354	3.651e-186	593.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
GZD2_k127_3476335_3	1163409.UUA_14549	7.229e-05	55.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1SEQH@1236|Gammaproteobacteria,1X5GV@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_3481827_2	926569.ANT_27600	6.747e-164	524.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
GZD2_k127_3481827_11	357808.RoseRS_1769	5.169e-43	164.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	-	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_21,RrnaAD
GZD2_k127_3481827_0	357808.RoseRS_1768	1.043e-276	855.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,3751K@32061|Chloroflexia	32061|Chloroflexia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GZD2_k127_3481827_9	383372.Rcas_2045	5.987e-81	275.0	COG1461@1|root,COG1461@2|Bacteria,2G8FK@200795|Chloroflexi,377ZB@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM dihydroxyacetone kinase, L subunit	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
GZD2_k127_3481827_1	383372.Rcas_2044	1.875e-186	586.0	COG2376@1|root,COG2376@2|Bacteria,2G80E@200795|Chloroflexi,376JR@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM dihydroxyacetone kinase, DhaK subunit	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
GZD2_k127_3481827_6	891968.Anamo_0101	6.831e-112	366.0	COG0580@1|root,COG0580@2|Bacteria,3TBQF@508458|Synergistetes	508458|Synergistetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
GZD2_k127_3481827_4	383372.Rcas_2042	5.485e-146	485.0	COG3284@1|root,COG3284@2|Bacteria,2GA8J@200795|Chloroflexi,375R4@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
GZD2_k127_3481827_7	1121904.ARBP01000026_gene687	1.519e-103	344.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GZD2_k127_3481827_3	1121904.ARBP01000026_gene688	3.973e-158	505.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,47NU3@768503|Cytophagia	976|Bacteroidetes	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GZD2_k127_3481827_10	592026.GCWU0000282_002681	4.267e-62	220.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GZD2_k127_3481827_8	926550.CLDAP_29720	5.442e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,2G7UH@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_3481827_5	383372.Rcas_2756	1.356e-112	368.0	COG4821@1|root,COG4821@2|Bacteria,2G6XP@200795|Chloroflexi	200795|Chloroflexi	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
GZD2_k127_3481827_12	697303.Thewi_2118	1.62e-16	81.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,42J2I@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GZD2_k127_348583_1	1242864.D187_009307	2.13e-07	53.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
GZD2_k127_348583_0	765420.OSCT_2237	6.571e-115	381.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_3491481_8	582402.Hbal_1875	6.434e-06	48.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2TT73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GZD2_k127_3491481_2	1382356.JQMP01000004_gene276	2.65e-126	416.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,27XFC@189775|Thermomicrobia	189775|Thermomicrobia	H	Nucleotidyl transferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GZD2_k127_3491481_0	926692.AZYG01000072_gene2731	5.641e-186	595.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
GZD2_k127_3491481_3	383372.Rcas_3054	8.007e-74	252.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
GZD2_k127_3491481_4	926569.ANT_28350	2.241e-32	128.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GZD2_k127_3491481_1	1265505.ATUG01000002_gene2213	7.036e-160	512.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2WPEY@28221|Deltaproteobacteria,2MKZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_3491481_7	926566.Terro_0451	2.055e-08	63.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD2_k127_3491481_6	357808.RoseRS_1462	6.773e-17	87.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD2_k127_3495088_2	926569.ANT_11650	8.053e-140	452.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
GZD2_k127_3495088_3	479434.Sthe_0091	1.319e-46	172.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD2_k127_3495088_4	926569.ANT_11660	9.58e-44	164.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
GZD2_k127_3495088_1	926569.ANT_11670	2.483e-154	492.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GZD2_k127_3495088_0	926569.ANT_11680	8.555e-155	504.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
GZD2_k127_3502868_1	926569.ANT_28850	2.772e-52	187.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
GZD2_k127_3502868_0	926550.CLDAP_40550	2.546e-59	213.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
GZD2_k127_3502868_2	926569.ANT_18820	2.366e-29	120.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	ko:K06039,ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
GZD2_k127_3503232_2	1480694.DC28_14010	1.904e-100	339.0	COG1653@1|root,COG1653@2|Bacteria,2J59Z@203691|Spirochaetes	203691|Spirochaetes	G	solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_3503232_1	926569.ANT_08100	2.725e-117	383.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GZD2_k127_3503232_0	926569.ANT_08110	4.695e-133	428.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_3507665_4	445970.ALIPUT_02586	0.0001343	50.0	2AA6P@1|root,30ZFR@2|Bacteria,4PDQD@976|Bacteroidetes,2FTPG@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3507665_2	1173028.ANKO01000017_gene201	3.402e-15	84.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria,1HDEC@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD2_k127_3507665_3	1134474.O59_001866	3.682e-13	75.0	2BQ62@1|root,32J0I@2|Bacteria,1QSS2@1224|Proteobacteria,1RWAF@1236|Gammaproteobacteria,1FHKA@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3507665_0	192952.MM_3157	8.017e-101	347.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
GZD2_k127_3507665_1	1267533.KB906735_gene4847	2.87e-15	78.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3508850_9	1192034.CAP_0785	5.153e-05	47.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0785|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3508850_3	926569.ANT_13890	9.918e-101	333.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3508850_1	926569.ANT_13900	1.21e-109	367.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_13900|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3508850_8	448385.sce0385	9.247e-49	188.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
GZD2_k127_3508850_0	926569.ANT_13960	5.127e-176	566.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GZD2_k127_3508850_5	926569.ANT_13970	1.839e-80	276.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GZD2_k127_3508850_2	926569.ANT_13980	1.145e-108	357.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD2_k127_3508850_4	926569.ANT_13990	1.083e-93	316.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD2_k127_3508850_6	926569.ANT_22890	1.809e-65	233.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GZD2_k127_3508850_7	926569.ANT_22900	2.987e-58	207.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
GZD2_k127_3517599_2	1121272.KB903289_gene4337	4.878e-19	97.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,Pentapeptide,Pkinase,TIR_2,Trypsin_2,WD40
GZD2_k127_3517599_0	945713.IALB_0056	9.766e-65	231.0	COG1028@1|root,COG1028@2|Bacteria	945713.IALB_0056|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3517599_4	325452.fgenesh_scip_prom.46568.1762	1.867e-16	91.0	COG2340@1|root,2S9B6@2759|Eukaryota,3Q74S@4776|Peronosporales	4776|Peronosporales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GZD2_k127_3517599_3	926569.ANT_22190	1.252e-18	98.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_3517599_1	164328.Phyra80475	3.91e-22	108.0	COG2340@1|root,2S9B6@2759|Eukaryota,3QBBA@4776|Peronosporales	4776|Peronosporales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GZD2_k127_3517599_6	4641.GSMUA_Achr9P01840_001	1.465e-07	63.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota,37HVT@33090|Viridiplantae,3GCJ1@35493|Streptophyta,3KXWT@4447|Liliopsida	35493|Streptophyta	S	Ig-like domain from next to BRCA1 gene	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
GZD2_k127_3517599_5	926569.ANT_25740	4.816e-08	58.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
GZD2_k127_3539095_6	626523.GCWU000342_00295	1.088e-05	51.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia	186801|Clostridia	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD2_k127_3539095_0	1121403.AUCV01000065_gene4170	3.015e-95	335.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
GZD2_k127_3539095_2	926569.ANT_04420	2.154e-32	128.0	COG3870@1|root,COG3870@2|Bacteria	2|Bacteria	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GZD2_k127_3539095_3	926569.ANT_04430	6.263e-19	89.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi	200795|Chloroflexi	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
GZD2_k127_3539095_4	1538295.JY96_04955	5.69e-08	65.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KJYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
GZD2_k127_3539095_5	1521187.JPIM01000033_gene2023	2.686e-06	59.0	COG0823@1|root,COG0823@2|Bacteria,2GB83@200795|Chloroflexi,377J2@32061|Chloroflexia	32061|Chloroflexia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3539095_1	1128421.JAGA01000002_gene1174	3.712e-34	139.0	COG1073@1|root,COG1073@2|Bacteria,2NQ4V@2323|unclassified Bacteria	2|Bacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD2_k127_3545745_10	926569.ANT_03090	8.924e-74	258.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GZD2_k127_3545745_4	926569.ANT_17980	5.884e-141	450.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
GZD2_k127_3545745_0	926569.ANT_17970	1.426e-262	813.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
GZD2_k127_3545745_2	926569.ANT_17960	1.197e-179	576.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
GZD2_k127_3545745_1	926569.ANT_17940	5.606e-191	602.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
GZD2_k127_3545745_11	926569.ANT_17930	9.21e-61	212.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GZD2_k127_3545745_13	926569.ANT_17920	1.723e-38	147.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GZD2_k127_3545745_12	316274.Haur_1215	1.1e-39	150.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
GZD2_k127_3545745_9	316274.Haur_1216	1.853e-78	271.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_3545745_8	926569.ANT_17910	1.012e-90	303.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	yaiS	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
GZD2_k127_3545745_6	1254432.SCE1572_20370	1.958e-101	335.0	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,42ZR1@68525|delta/epsilon subdivisions,2WV1F@28221|Deltaproteobacteria,2YZWT@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GZD2_k127_3545745_7	926569.ANT_17900	6.478e-91	309.0	COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_3545745_3	926569.ANT_17720	2.146e-151	489.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GZD2_k127_3545745_15	318464.IO99_02130	2.03e-31	128.0	COG0454@1|root,COG0456@2|Bacteria,1V9DS@1239|Firmicutes,24GMP@186801|Clostridia,36IEY@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_3545745_16	247490.KSU1_C0844	6.084e-16	91.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
GZD2_k127_3545745_5	926569.ANT_21040	2.87e-137	451.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GZD2_k127_3552221_5	926569.ANT_25240	6.663e-27	118.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_3552221_2	552811.Dehly_0558	7.995e-119	402.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD2_k127_3552221_4	243164.DET0571	4.984e-70	255.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GZD2_k127_3552221_1	926569.ANT_06790	1.723e-120	392.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GZD2_k127_3552221_3	926569.ANT_06780	1.497e-93	308.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
GZD2_k127_3552221_0	926569.ANT_06770	7.849e-124	402.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_3552221_6	383372.Rcas_0802	4.005e-18	86.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
GZD2_k127_3554135_0	926569.ANT_18310	8.102e-298	926.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD2_k127_3554135_10	926569.ANT_18320	6.194e-25	109.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413,ko:K07719	ko02020,ko02030,map02020,map02030	M00506,M00518	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg,YcbB
GZD2_k127_3554135_9	1444309.JAQG01000157_gene3217	7.225e-29	120.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HQNT@91061|Bacilli,26XKA@186822|Paenibacillaceae	91061|Bacilli	K	GCN5 family acetyltransferase	-	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GZD2_k127_3554135_6	926569.ANT_18330	1.122e-61	217.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
GZD2_k127_3554135_5	926569.ANT_20860	4.483e-72	249.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GZD2_k127_3554135_4	926569.ANT_20880	8.834e-100	338.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD2_k127_3554135_2	1356854.N007_03230	1.215e-158	511.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GZD2_k127_3554135_3	926550.CLDAP_06710	1.199e-118	392.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD2_k127_3554135_1	926569.ANT_11410	1.706e-238	755.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GZD2_k127_3554135_7	926569.ANT_26570	3.619e-47	173.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_3558435_2	1235457.C404_25045	1.792e-72	253.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_3558435_1	1382306.JNIM01000001_gene1820	3.901e-82	291.0	COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF,HATPase_c,HisKA
GZD2_k127_3558435_0	1267535.KB906767_gene3326	4.176e-113	381.0	COG1028@1|root,COG1028@2|Bacteria	1267535.KB906767_gene3326|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3558435_3	1293054.HSACCH_00981	2.092e-62	220.0	COG0395@1|root,COG0395@2|Bacteria,1V3Y9@1239|Firmicutes,25C5H@186801|Clostridia,3WBP0@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_3563231_3	926569.ANT_05610	4.918e-65	230.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
GZD2_k127_3563231_5	926560.KE387027_gene705	5.13e-45	166.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
GZD2_k127_3563231_6	926560.KE387027_gene706	6.003e-11	71.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	2.1.1.14	ko:K00549,ko:K04085	ko00270,ko00450,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map01100,map01110,map01230,map04122	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Meth_synt_2,OsmC,SnoaL_2,TusA
GZD2_k127_3563231_7	1380347.JNII01000008_gene4391	6.639e-07	59.0	COG0425@1|root,COG0425@2|Bacteria,2GSNH@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GZD2_k127_3563231_0	1121377.KB906436_gene921	4.134e-191	627.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GZD2_k127_3563231_2	926550.CLDAP_14250	1.212e-113	376.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD2_k127_3563231_1	1121382.JQKG01000005_gene3282	4.691e-126	423.0	COG0249@1|root,COG0249@2|Bacteria,1WJFP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
GZD2_k127_3563231_4	1144275.COCOR_01200	1.467e-51	191.0	COG1397@1|root,COG1397@2|Bacteria,1N4A8@1224|Proteobacteria,432CQ@68525|delta/epsilon subdivisions,2WYFP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3565933_0	926569.ANT_02350	6.262e-133	431.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_3565933_1	1499967.BAYZ01000104_gene3692	1.254e-92	325.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_3565933_2	1463934.JOCF01000021_gene1702	3.898e-41	168.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_3577206_3	479433.Caci_8915	4.404e-13	81.0	2ES6T@1|root,33JRJ@2|Bacteria,2I9QF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3577206_1	1120973.AQXL01000128_gene2783	3.401e-44	171.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,279ZC@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GZD2_k127_3577206_2	1122194.AUHU01000007_gene315	1.042e-43	161.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,467XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GZD2_k127_3577206_0	56780.SYN_01619	1.053e-87	298.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42TPN@68525|delta/epsilon subdivisions,2X20U@28221|Deltaproteobacteria,2MSGP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
GZD2_k127_3579744_1	926560.KE387023_gene3058	4.432e-104	358.0	COG3501@1|root,COG3501@2|Bacteria,1WKZI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3579744_4	1382306.JNIM01000001_gene3322	6.172e-38	152.0	COG3628@1|root,COG3628@2|Bacteria,2G7CQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
GZD2_k127_3579744_0	1382306.JNIM01000001_gene3321	4.386e-175	570.0	COG3299@1|root,COG3299@2|Bacteria,2G84U@200795|Chloroflexi	200795|Chloroflexi	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
GZD2_k127_3579744_3	1382306.JNIM01000001_gene3320	7.153e-48	184.0	COG1716@1|root,COG4385@1|root,COG1716@2|Bacteria,COG4385@2|Bacteria,2G7Z7@200795|Chloroflexi	200795|Chloroflexi	T	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Tail_P2_I
GZD2_k127_3579744_5	765420.OSCT_0637	2.736e-29	122.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_3579744_2	1322246.BN4_12190	4.994e-50	188.0	COG0583@1|root,COG0583@2|Bacteria,1MV0E@1224|Proteobacteria,42SGR@68525|delta/epsilon subdivisions,2WPDS@28221|Deltaproteobacteria,2MBMQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	regulatory protein LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GZD2_k127_3583669_1	329726.AM1_5157	9.49e-50	186.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CbiA,NB-ARC,TIR_2,TPR_10,TPR_12
GZD2_k127_3583669_0	926550.CLDAP_38240	1.038e-258	807.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD2_k127_3589455_1	871968.DESME_07925	8.61e-65	232.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_3589455_0	635013.TherJR_0872	1.905e-87	298.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,260XG@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GZD2_k127_3592750_3	639282.DEFDS_0814	6.119e-61	216.0	COG0372@1|root,COG0372@2|Bacteria,2GEZB@200930|Deferribacteres	200930|Deferribacteres	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GZD2_k127_3592750_1	765420.OSCT_2981	8.02e-120	393.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
GZD2_k127_3592750_2	383372.Rcas_0680	1.641e-107	357.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi,376IE@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_3592750_0	926569.ANT_11050	6.328e-201	636.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GZD2_k127_3592750_4	926569.ANT_14580	8.251e-47	179.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	comC	-	3.4.23.43	ko:K02236,ko:K02506,ko:K02654	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
GZD2_k127_3592750_5	1157640.AQWO01000007_gene3565	1.103e-15	91.0	COG3391@1|root,COG3391@2|Bacteria,2H4SV@201174|Actinobacteria	201174|Actinobacteria	MU	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
GZD2_k127_3592750_8	867903.ThesuDRAFT_00034	1.102e-08	62.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
GZD2_k127_3592750_7	319003.Bra1253DRAFT_01612	3.044e-09	69.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GZD2_k127_3592750_6	1082933.MEA186_09690	2.441e-11	76.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria,43N9X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GZD2_k127_3592844_1	1499967.BAYZ01000027_gene1815	1.135e-131	426.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GZD2_k127_3592844_3	926569.ANT_23190	1.009e-107	363.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GZD2_k127_3592844_0	1408473.JHXO01000011_gene3193	1.931e-147	473.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,2FWDF@200643|Bacteroidia	976|Bacteroidetes	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
GZD2_k127_3592844_2	383372.Rcas_1300	2.407e-131	460.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
GZD2_k127_3608379_0	1128421.JAGA01000001_gene2415	1.656e-90	306.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_3608379_2	292.DM42_3595	5.043e-33	145.0	COG4585@1|root,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1K250@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_9
GZD2_k127_3608379_1	1449351.RISW2_17940	6.179e-53	205.0	COG3920@1|root,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2U6IX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_3,PAS_4
GZD2_k127_3609167_4	1122611.KB903956_gene170	3.428e-17	94.0	COG3409@1|root,COG3409@2|Bacteria,2IFDD@201174|Actinobacteria,4EQWY@85012|Streptosporangiales	201174|Actinobacteria	M	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD2_k127_3609167_5	28444.JODQ01000006_gene222	2.676e-15	88.0	COG3409@1|root,COG5401@1|root,COG3409@2|Bacteria,COG5401@2|Bacteria,2IFDD@201174|Actinobacteria,4EQWY@85012|Streptosporangiales	201174|Actinobacteria	M	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD2_k127_3609167_6	926569.ANT_18580	0.0008308	50.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GZD2_k127_3609167_0	926550.CLDAP_18740	1.128e-83	289.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GZD2_k127_3609167_1	102129.Lepto7375DRAFT_7033	4.925e-34	153.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
GZD2_k127_3609167_2	485916.Dtox_0050	2.145e-31	144.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	kinE	-	2.7.13.3	ko:K02482,ko:K02491,ko:K13533,ko:K14986	ko02020,map02020	M00485,M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_3609167_3	357808.RoseRS_4452	1.603e-25	125.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
GZD2_k127_3621219_5	926569.ANT_22900	2.846e-32	130.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
GZD2_k127_3621219_7	268739.Nmlp_2530	8.693e-17	93.0	COG0515@1|root,COG1520@1|root,arCOG02492@2157|Archaea,arCOG03682@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
GZD2_k127_3621219_4	926569.ANT_22920	7.249e-46	166.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GZD2_k127_3621219_8	316274.Haur_0766	2.16e-16	83.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia	32061|Chloroflexia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GZD2_k127_3621219_6	926569.ANT_22940	1.812e-18	86.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GZD2_k127_3621219_2	671143.DAMO_1521	3.216e-76	262.0	COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria	2|Bacteria	P	TrkA-C domain	trkA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD2_k127_3621219_3	671143.DAMO_1520	5.809e-72	249.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD2_k127_3621219_0	671143.DAMO_0407	5.217e-277	865.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_3621219_1	671143.DAMO_0407	2.02e-199	632.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_3621582_1	1306174.JODP01000002_gene5612	9.783e-174	563.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GZD2_k127_3621582_3	292459.STH1288	7.865e-50	181.0	2ERAK@1|root,33IW8@2|Bacteria,1VNK2@1239|Firmicutes,257CY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3621582_5	1121468.AUBR01000002_gene712	1.815e-22	100.0	2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,24MJ2@186801|Clostridia,42IHG@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
GZD2_k127_3621582_0	926569.ANT_19070	1.496e-235	739.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GZD2_k127_3621582_2	926569.ANT_19050	3.154e-84	289.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GZD2_k127_3624352_2	926569.ANT_10660	1.574e-53	190.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GZD2_k127_3624352_0	926569.ANT_10660	2.613e-128	416.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GZD2_k127_3624352_3	1380390.JIAT01000010_gene3702	1.524e-49	203.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CS9K@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HisKA_3
GZD2_k127_3624352_4	283699.D172_0596	2.522e-11	78.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1S0C5@1236|Gammaproteobacteria,2Q1YA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_8,PAS_9
GZD2_k127_3624352_1	196367.JNFG01000199_gene3491	4.899e-91	335.0	COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,1K5TA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
GZD2_k127_3625823_2	383372.Rcas_0901	6.122e-138	448.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi,3759W@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GZD2_k127_3625823_0	926569.ANT_05060	1.466e-223	696.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GZD2_k127_3625823_1	926569.ANT_28570	3.128e-188	596.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
GZD2_k127_3625823_4	926569.ANT_28580	3.443e-109	360.0	COG0395@1|root,COG0395@2|Bacteria,2G7UM@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GZD2_k127_3625823_3	926569.ANT_28590	1.229e-114	376.0	COG1175@1|root,COG1175@2|Bacteria,2G8B0@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
GZD2_k127_3629443_2	935836.JAEL01000052_gene870	7.97e-25	120.0	COG1502@1|root,COG2374@1|root,COG1502@2|Bacteria,COG2374@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,1ZJTB@1386|Bacillus	91061|Bacilli	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PLDc_2
GZD2_k127_3629443_3	525904.Tter_0496	9.267e-16	91.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
GZD2_k127_3629443_0	926569.ANT_28360	6.26e-89	299.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GZD2_k127_3629443_1	926569.ANT_28370	1.593e-54	201.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GZD2_k127_3629443_4	1321778.HMPREF1982_02132	9.271e-13	72.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3643786_1	756499.Desde_1419	1.798e-160	516.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GZD2_k127_3643786_5	1382358.JHVN01000025_gene1446	2.631e-13	74.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,21X1C@150247|Anoxybacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GZD2_k127_3643786_6	243159.AFE_1176	3.306e-07	54.0	2961X@1|root,2ZTCF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3643786_0	926569.ANT_12650	9.479e-290	898.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GZD2_k127_3643786_4	931276.Cspa_c24300	2.189e-30	130.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
GZD2_k127_3643786_2	926569.ANT_09090	3.726e-76	270.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
GZD2_k127_3654404_6	244447.XP_008324421.1	9.115e-05	53.0	COG1028@1|root,KOG4170@1|root,KOG0725@2759|Eukaryota,KOG4170@2759|Eukaryota,38DZE@33154|Opisthokonta,3BA0D@33208|Metazoa,3CVGY@33213|Bilateria,480GA@7711|Chordata,49406@7742|Vertebrata,49ZAM@7898|Actinopterygii	33208|Metazoa	I	Hydroxysteroid dehydrogenase like 2	HSDL2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	SCP2,adh_short
GZD2_k127_3654404_5	1120949.KB903329_gene9218	4.624e-08	58.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3654404_2	765420.OSCT_2236	2.473e-61	221.0	COG3292@1|root,COG3829@1|root,COG4585@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2G7P1@200795|Chloroflexi	200795|Chloroflexi	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
GZD2_k127_3654404_1	42256.RradSPS_0358	5.223e-131	452.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GZD2_k127_3654404_0	768704.Desmer_1343	4.254e-179	592.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,25B73@186801|Clostridia,263UP@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, luxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GZD2_k127_3670898_1	1040986.ATYO01000029_gene3428	3.692e-53	191.0	COG1477@1|root,COG1477@2|Bacteria,1NKWD@1224|Proteobacteria	1224|Proteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GZD2_k127_3670898_0	485913.Krac_7104	1.21e-148	485.0	COG1018@1|root,COG1018@2|Bacteria,2G9BE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
GZD2_k127_3670898_3	768671.ThimaDRAFT_0740	1.103e-21	105.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,1T4CS@1236|Gammaproteobacteria,1WZQU@135613|Chromatiales	135613|Chromatiales	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_3670898_2	1449353.JQMQ01000004_gene6527	6.044e-37	141.0	2EKKQ@1|root,33EAI@2|Bacteria,2H1EK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3698380_1	926569.ANT_08290	3.992e-15	76.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GZD2_k127_3698380_0	926569.ANT_09200	1.358e-154	495.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD2_k127_3708130_0	485913.Krac_11194	2.47e-177	563.0	COG0520@1|root,COG0520@2|Bacteria,2G7ZH@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GZD2_k127_3708130_1	926554.KI912671_gene402	5.866e-154	497.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
GZD2_k127_3715383_0	1499967.BAYZ01000171_gene5534	1.63e-81	282.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
GZD2_k127_3715383_2	926569.ANT_29860	5.075e-35	139.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3715383_1	926569.ANT_29850	1.49e-65	238.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3740479_1	1122182.KB903813_gene2669	2.537e-76	264.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
GZD2_k127_3740479_0	926569.ANT_27410	2.649e-315	972.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GZD2_k127_3746997_0	926569.ANT_23780	8.637e-75	258.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
GZD2_k127_3746997_2	290315.Clim_1935	3.801e-08	58.0	2EF3C@1|root,338WF@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
GZD2_k127_3746997_3	2850.Phatr46303	0.0006633	48.0	2AHTF@1|root,2SGI2@2759|Eukaryota,2XH5J@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3746997_1	99598.Cal7507_0551	1.093e-37	153.0	COG0500@1|root,COG2226@2|Bacteria,1G0TQ@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_3763504_0	926569.ANT_29920	2.33e-244	775.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GZD2_k127_3763504_1	926550.CLDAP_30050	4.872e-58	209.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_30050|-	T	phosphorelay signal transduction system	-	-	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
GZD2_k127_3763504_2	926569.ANT_28790	9.808e-29	116.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
GZD2_k127_3773392_2	1128421.JAGA01000004_gene2663	1.063e-81	287.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K10118,ko:K15771	ko02010,map02010	M00196,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28	-	-	BPD_transp_1
GZD2_k127_3773392_1	1128421.JAGA01000004_gene2662	1.032e-81	281.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_3773392_0	926569.ANT_24940	3.234e-296	923.0	COG1554@1|root,COG1554@2|Bacteria,2G5P0@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 65 central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
GZD2_k127_3792331_2	926569.ANT_09820	9.902e-102	351.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G97C@200795|Chloroflexi	200795|Chloroflexi	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD2_k127_3792331_0	926569.ANT_09830	3.574e-144	488.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HD,HD_5,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_3792331_1	926569.ANT_09840	1.259e-115	378.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GZD2_k127_3792331_5	926569.ANT_09850	4.317e-37	148.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3792331_4	926569.ANT_09860	6.426e-39	152.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GZD2_k127_3792331_3	926569.ANT_09870	1.01e-73	258.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GZD2_k127_3817406_0	32057.KB217478_gene966	1.042e-116	385.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_3817406_1	195250.CM001776_gene942	2.8e-95	325.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_3817406_2	670292.JH26_05185	2.841e-39	149.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase,GFO_IDH_MocA,GFO_IDH_MocA_C,NAD_binding_10
GZD2_k127_38309_1	402880.MmarC5_1265	7.055e-40	160.0	COG0726@1|root,arCOG02878@2157|Archaea,2Y5YX@28890|Euryarchaeota	28890|Euryarchaeota	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD2_k127_38309_2	1235798.C817_00152	1.553e-30	134.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_38309_0	1380394.JADL01000003_gene4824	1.647e-48	185.0	COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,2TSXX@28211|Alphaproteobacteria,2JS0U@204441|Rhodospirillales	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	dapAch4	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
GZD2_k127_3831778_3	926569.ANT_19690	2.082e-34	133.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_3831778_1	357808.RoseRS_3404	6.451e-79	269.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia	32061|Chloroflexia	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
GZD2_k127_3831778_2	626887.J057_06391	4.481e-50	190.0	COG0589@1|root,COG0589@2|Bacteria,1NAHQ@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD2_k127_3831778_0	1123269.NX02_01920	1.293e-286	928.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2K0DW@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_trans_2_3,Glyco_transf_36,Glycoamylase
GZD2_k127_3840717_4	926569.ANT_06520	4.422e-37	143.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_3840717_5	1450525.JATV01000008_gene674	2.784e-36	141.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia,2NWWP@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GZD2_k127_3840717_0	926569.ANT_06500	1.709e-147	472.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GZD2_k127_3840717_3	661478.OP10G_0619	8.178e-61	229.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
GZD2_k127_3840717_1	926569.ANT_06490	6.941e-85	287.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,RraA-like
GZD2_k127_3840717_6	926569.ANT_22190	5.382e-19	98.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_3840717_2	926569.ANT_22190	2.343e-65	237.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
GZD2_k127_3843062_0	485913.Krac_7358	3.151e-237	742.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GZD2_k127_3843062_1	985053.VMUT_0700	3.588e-24	111.0	COG0500@1|root,arCOG01631@2157|Archaea,2XQ7P@28889|Crenarchaeota	28889|Crenarchaeota	Q	RNA methylase	-	GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	CMAS,DOT1,Methyltransf_25,Methyltransf_31,PrmA
GZD2_k127_3843062_2	926550.CLDAP_34260	2.716e-11	70.0	COG0477@1|root,COG2814@2|Bacteria,2G96S@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_3844530_4	926550.CLDAP_05160	3.251e-12	68.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_3844530_3	746697.Aeqsu_2695	2.745e-13	82.0	COG2815@1|root,COG2815@2|Bacteria,4NXFG@976|Bacteroidetes,1I6HM@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	TIR_2
GZD2_k127_3844530_0	1382356.JQMP01000004_gene492	4.098e-98	332.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD2_k127_3844530_1	926569.ANT_14540	9.452e-36	147.0	COG0115@1|root,COG0115@2|Bacteria,2G8EE@200795|Chloroflexi	200795|Chloroflexi	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GZD2_k127_3844530_2	497965.Cyan7822_3776	7.331e-20	99.0	2EWXB@1|root,33Q8Q@2|Bacteria,1GBP2@1117|Cyanobacteria,3KJC6@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3853313_0	926569.ANT_22070	1.178e-106	353.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	1.6.5.3	ko:K00342,ko:K00343,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GZD2_k127_3853313_1	926569.ANT_22050	4.196e-73	249.0	COG3260@1|root,COG3260@2|Bacteria,2G8XX@200795|Chloroflexi	200795|Chloroflexi	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	echC	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
GZD2_k127_3853313_2	926569.ANT_22030	3.629e-57	211.0	COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi	200795|Chloroflexi	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
GZD2_k127_388220_0	63737.Npun_DF037	1.533e-145	465.0	COG1063@1|root,COG1063@2|Bacteria,1GCHD@1117|Cyanobacteria,1HQHG@1161|Nostocales	1117|Cyanobacteria	E	Alcohol dehydrogenase GroES-associated	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
GZD2_k127_388220_1	1210884.HG799463_gene9424	2.354e-62	224.0	COG5637@1|root,COG5637@2|Bacteria,2IZQD@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
GZD2_k127_388220_2	1121033.AUCF01000014_gene1350	1.697e-35	141.0	2DN17@1|root,32UV9@2|Bacteria,1N33U@1224|Proteobacteria,2UC5D@28211|Alphaproteobacteria,2JTTN@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3892878_3	398512.JQKC01000032_gene4454	1.145e-12	74.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,3WIWY@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
GZD2_k127_3892878_2	357808.RoseRS_2461	2.649e-177	568.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi	200795|Chloroflexi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
GZD2_k127_3892878_1	926569.ANT_01050	2.944e-184	581.0	COG0240@1|root,COG0240@2|Bacteria,2G6HJ@200795|Chloroflexi	200795|Chloroflexi	C	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	NAD_Gly3P_dh_N,Octopine_DH
GZD2_k127_3892878_0	926569.ANT_01060	5.897e-227	711.0	COG5012@1|root,COG5012@2|Bacteria,2G66F@200795|Chloroflexi	200795|Chloroflexi	D	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
GZD2_k127_3898874_1	756067.MicvaDRAFT_5224	5.514e-83	313.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
GZD2_k127_3898874_0	981384.AEYW01000001_gene1562	4.879e-177	601.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
GZD2_k127_3898874_3	880072.Desac_0096	5.165e-17	84.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
GZD2_k127_3898874_2	880072.Desac_0095	1.533e-46	171.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
GZD2_k127_3908239_4	63737.Npun_R1399	2.953e-30	125.0	COG0656@1|root,COG0656@2|Bacteria,1G6K0@1117|Cyanobacteria,1HNPA@1161|Nostocales	1117|Cyanobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Ntox11
GZD2_k127_3908239_5	136273.GY22_14525	1.554e-29	119.0	COG4104@1|root,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
GZD2_k127_3908239_3	489825.LYNGBM3L_04050	1.272e-30	132.0	2B7HA@1|root,320MA@2|Bacteria,1GRAH@1117|Cyanobacteria,1HFHN@1150|Oscillatoriales	1117|Cyanobacteria	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4255
GZD2_k127_3908239_0	1157635.KB892011_gene1212	4.91e-131	432.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria	201174|Actinobacteria	S	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
GZD2_k127_3908239_1	1382306.JNIM01000001_gene3330	9.421e-50	181.0	2ACY3@1|root,312JQ@2|Bacteria,2G8H3@200795|Chloroflexi	200795|Chloroflexi	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
GZD2_k127_3908239_2	298653.Franean1_3818	1.253e-33	133.0	arCOG11412@1|root,31S84@2|Bacteria,2IHRW@201174|Actinobacteria,4ET6M@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3908239_7	489825.LYNGBM3L_05130	7.748e-20	95.0	2DMQT@1|root,32T2H@2|Bacteria,1G73M@1117|Cyanobacteria,1HC20@1150|Oscillatoriales	1117|Cyanobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
GZD2_k127_3908239_6	383372.Rcas_2818	1.305e-20	96.0	COG1652@1|root,COG1652@2|Bacteria,2G7PE@200795|Chloroflexi	200795|Chloroflexi	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_3912165_1	1034347.CAHJ01000072_gene2723	9.461e-16	80.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4HC74@91061|Bacilli,1ZC5P@1386|Bacillus	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	nreC	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_3912165_0	1408224.SAMCCGM7_c6572	1.162e-235	773.0	COG1352@1|root,COG2201@1|root,COG2433@1|root,COG3920@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2433@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2TW1K@28211|Alphaproteobacteria,4BB0U@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	Protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HWE_HK,PAS_10,PAS_3,PAS_4,PAS_9
GZD2_k127_3917342_7	292459.STH2398	2.15e-46	176.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
GZD2_k127_3917342_6	926569.ANT_16140	1.819e-82	285.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD2_k127_3917342_5	765420.OSCT_1016	2.839e-99	335.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD2_k127_3917342_2	926569.ANT_23640	1.573e-179	578.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
GZD2_k127_3917342_4	926569.ANT_23650	1.85e-110	385.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
GZD2_k127_3917342_1	926569.ANT_22580	2.464e-187	610.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GZD2_k127_3917342_3	926569.ANT_25070	1.269e-132	430.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GZD2_k127_3917342_8	926569.ANT_25060	8.85e-38	148.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GZD2_k127_3917342_0	926569.ANT_25050	2.362e-299	924.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GZD2_k127_391984_9	926569.ANT_25970	3.95e-05	46.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD2_k127_391984_6	926550.CLDAP_05830	2.006e-07	64.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
GZD2_k127_391984_7	1521187.JPIM01000022_gene618	5.652e-06	59.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD2_k127_391984_8	867845.KI911784_gene1801	5.652e-06	59.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD2_k127_391984_1	765420.OSCT_3196	7.434e-73	268.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_391984_10	1379270.AUXF01000002_gene1385	5.647e-05	50.0	2E5Q6@1|root,330ET@2|Bacteria,1ZU87@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_391984_2	765420.OSCT_3196	5.694e-65	244.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_391984_3	1499967.BAYZ01000095_gene4130	2.735e-44	169.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	pfs	-	3.2.2.1,3.2.2.9,4.1.99.14	ko:K01239,ko:K01243,ko:K03716	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GZD2_k127_391984_4	1541065.JRFE01000032_gene3664	2.137e-36	144.0	COG0454@1|root,COG0456@2|Bacteria,1G7ME@1117|Cyanobacteria,3VK6H@52604|Pleurocapsales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
GZD2_k127_391984_0	926569.ANT_16530	1.808e-128	424.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_391984_5	1121920.AUAU01000013_gene1701	2.863e-10	62.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_3920346_2	1121866.AUGK01000010_gene452	1.737e-22	100.0	COG0640@1|root,COG0640@2|Bacteria,2GUDD@201174|Actinobacteria,4CW8F@84998|Coriobacteriia	84998|Coriobacteriia	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD2_k127_3920346_1	1335757.SPICUR_04025	4.605e-33	137.0	COG1814@1|root,COG1814@2|Bacteria,1RBDP@1224|Proteobacteria,1T04K@1236|Gammaproteobacteria,1X0M0@135613|Chromatiales	135613|Chromatiales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GZD2_k127_3920346_0	1499967.BAYZ01000069_gene1853	6.275e-194	614.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD2_k127_3927695_2	1120971.AUCA01000001_gene1699	1.229e-38	155.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GZD2_k127_3927695_0	330084.JNYZ01000005_gene928	2.988e-82	286.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4DZ95@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD2_k127_3927695_1	1121926.AXWO01000014_gene1775	6.738e-68	247.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4EZ85@85014|Glycomycetales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_3928214_3	82654.Pse7367_3373	1.478e-23	118.0	COG0683@1|root,COG2202@1|root,COG5002@1|root,COG0683@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GQB3@1117|Cyanobacteria,1H7YF@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	HAMP,HATPase_c,HisKA,PAS_4
GZD2_k127_3928214_2	316274.Haur_4114	2.863e-43	182.0	COG2203@1|root,COG3605@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
GZD2_k127_3928214_0	926569.ANT_11790	7.642e-82	280.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
GZD2_k127_3928214_1	926569.ANT_11800	6.607e-69	243.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_3930827_2	1128427.KB904821_gene4609	0.000316	52.0	COG2755@1|root,COG2755@2|Bacteria,1FZYY@1117|Cyanobacteria,1H9GA@1150|Oscillatoriales	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1574
GZD2_k127_3930827_0	926569.ANT_13120	1.065e-174	564.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GZD2_k127_393506_2	102129.Lepto7375DRAFT_1200	1.417e-29	129.0	COG1216@1|root,COG1216@2|Bacteria,1G2FF@1117|Cyanobacteria,1H9CV@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_393506_0	383372.Rcas_1348	2.843e-44	173.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_393506_1	452652.KSE_08140	1.285e-41	167.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,2M3MH@2063|Kitasatospora	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_3950173_2	926569.ANT_06540	1.743e-44	164.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_3950173_0	926569.ANT_06530	9.072e-102	338.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
GZD2_k127_3950173_3	714943.Mucpa_3893	1.698e-18	99.0	COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes,1IVBY@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_3950173_1	926569.ANT_06520	3.694e-83	278.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_3952082_3	485916.Dtox_1806	2.956e-13	81.0	COG5662@1|root,COG5662@2|Bacteria,1U13D@1239|Firmicutes,24AF3@186801|Clostridia,262HU@186807|Peptococcaceae	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,DUF4367,zf-HC2
GZD2_k127_3952082_0	479434.Sthe_2191	2.848e-91	309.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_3952082_1	357808.RoseRS_3279	3.994e-62	225.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GZD2_k127_3952082_2	264732.Moth_1900	1.781e-51	188.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia,42FFN@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_3956170_2	926550.CLDAP_10960	2.302e-43	163.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GZD2_k127_3956170_0	926569.ANT_30500	0.0	1176.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
GZD2_k127_3956170_3	743719.PaelaDRAFT_5288	3.385e-26	108.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,26ZRV@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
GZD2_k127_3956170_4	926550.CLDAP_35170	1.899e-25	108.0	COG0346@1|root,COG0346@2|Bacteria,2G9TR@200795|Chloroflexi	200795|Chloroflexi	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GZD2_k127_3968790_1	926569.ANT_10770	4.677e-95	320.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartokinase family	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
GZD2_k127_3968790_0	1382306.JNIM01000001_gene2737	2.793e-142	467.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
GZD2_k127_3968790_2	926550.CLDAP_35520	3.887e-24	106.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GZD2_k127_3974522_2	247490.KSU1_D0469	2.183e-32	127.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_3974522_0	211165.AJLN01000104_gene6508	1.066e-136	442.0	COG0438@1|root,COG0438@2|Bacteria,1G0AB@1117|Cyanobacteria,1JHZZ@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
GZD2_k127_3974522_1	247490.KSU1_D0467	1.356e-103	347.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD2_k127_4010987_3	1198114.AciX9_1790	3.252e-74	254.0	COG0451@1|root,COG0451@2|Bacteria,3Y3J3@57723|Acidobacteria,2JIFZ@204432|Acidobacteriia	204432|Acidobacteriia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_4010987_2	926569.ANT_06580	9.96e-89	299.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
GZD2_k127_4010987_6	886377.Murru_1368	1.436e-19	103.0	COG3307@1|root,COG3307@2|Bacteria,4NJTN@976|Bacteroidetes,1HZ54@117743|Flavobacteriia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD2_k127_4010987_5	65393.PCC7424_5869	9.085e-22	107.0	2CGDF@1|root,34388@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4010987_0	926569.ANT_04130	2.568e-144	477.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD2_k127_4010987_4	926569.ANT_04120	2.272e-61	220.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GZD2_k127_4010987_1	926569.ANT_23050	1.891e-90	303.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
GZD2_k127_4014279_1	868131.MSWAN_0806	6.669e-94	316.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
GZD2_k127_4014279_4	1173027.Mic7113_5589	7.078e-47	173.0	COG1051@1|root,COG1051@2|Bacteria,1GBA9@1117|Cyanobacteria,1HGUB@1150|Oscillatoriales	1117|Cyanobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_4014279_0	1045855.DSC_11095	7.556e-165	537.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4VE@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
GZD2_k127_4014279_6	760192.Halhy_1206	1.868e-31	130.0	2DMXT@1|root,32UAK@2|Bacteria,4NWD1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4014279_2	717606.PaecuDRAFT_4438	1.193e-62	223.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_4014279_7	292459.STH1553	1.431e-13	74.0	2C6RI@1|root,2ZSYS@2|Bacteria,1W373@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4014279_3	1117318.PRUB_21782	3.262e-56	200.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,1SASB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GZD2_k127_4014279_5	211165.AJLN01000045_gene259	3.736e-40	154.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1JIKJ@1189|Stigonemataceae	1117|Cyanobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
GZD2_k127_403713_3	926569.ANT_25530	3.885e-10	65.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD2_k127_403713_0	926569.ANT_05540	1.561e-133	434.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
GZD2_k127_403713_4	1289387.AUKW01000009_gene4346	1.837e-06	61.0	COG2182@1|root,COG2182@2|Bacteria,2I2J8@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_403713_2	926569.ANT_23620	1.153e-27	118.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
GZD2_k127_403713_1	926569.ANT_23610	6.654e-101	330.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GZD2_k127_4088468_3	485913.Krac_8762	1.323e-86	293.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_4088468_1	429009.Adeg_2132	1.561e-115	388.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,42FKX@68295|Thermoanaerobacterales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
GZD2_k127_4088468_0	580331.Thit_0565	4.143e-140	460.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
GZD2_k127_4088468_2	926550.CLDAP_40520	3.033e-92	307.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GZD2_k127_4097629_0	1448860.BBJO01000008_gene659	1.14e-126	414.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,23S6X@183963|Halobacteria	183963|Halobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
GZD2_k127_4097629_2	926569.ANT_29500	3.469e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_4097629_1	1128421.JAGA01000003_gene3678	1.107e-93	338.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
GZD2_k127_410064_6	228405.HNE_0866	1.595e-09	69.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,43X09@69657|Hyphomonadaceae	28211|Alphaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GZD2_k127_410064_1	296591.Bpro_1676	5.936e-91	308.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_410064_0	1480694.DC28_05675	6.185e-102	342.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_410064_3	1380370.JIBA01000011_gene3347	1.495e-36	152.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GZD2_k127_410064_5	1033734.CAET01000024_gene1120	2.602e-30	133.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,1ZCVI@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_410064_2	760568.Desku_1231	2.961e-72	256.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
GZD2_k127_410064_4	926550.CLDAP_15400	4.15e-32	130.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GZD2_k127_4104045_7	1443665.JACA01000041_gene1584	0.0008164	48.0	COG1476@1|root,COG1476@2|Bacteria,4NVQ6@976|Bacteroidetes,1I51D@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GZD2_k127_4104045_6	525904.Tter_0346	2.776e-14	77.0	COG0762@1|root,COG0762@2|Bacteria,2NRP0@2323|unclassified Bacteria	2|Bacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
GZD2_k127_4104045_3	1128421.JAGA01000002_gene1800	1.783e-39	151.0	COG2166@1|root,COG2166@2|Bacteria	2|Bacteria	S	iron-sulfur cluster assembly	sufE	-	-	ko:K02426,ko:K07125	-	-	-	-	ko00000	-	-	-	SufE
GZD2_k127_4104045_0	926569.ANT_27870	7.665e-128	417.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
GZD2_k127_4104045_4	324602.Caur_1140	7.121e-39	159.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF,HAMP
GZD2_k127_4104045_1	926569.ANT_04330	1.008e-53	197.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GZD2_k127_4104045_5	926569.ANT_04340	2.996e-22	99.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	mec	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
GZD2_k127_4110415_1	316274.Haur_3300	1.901e-96	327.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_4110415_0	926569.ANT_18360	5.817e-98	322.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GZD2_k127_4116580_1	765420.OSCT_2889	4.875e-62	221.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,376FV@32061|Chloroflexia	32061|Chloroflexia	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
GZD2_k127_4116580_3	114615.BRADO1750	7.036e-17	86.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,2TVQV@28211|Alphaproteobacteria,3JSW2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GZD2_k127_4116580_0	105559.Nwat_1327	1.81e-67	234.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,1WY4U@135613|Chromatiales	135613|Chromatiales	P	PFAM Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GZD2_k127_4116580_2	1242864.D187_001135	9.735e-21	98.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GZD2_k127_4121664_1	926569.ANT_29940	3.055e-135	463.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,2G7KJ@200795|Chloroflexi	200795|Chloroflexi	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_12
GZD2_k127_4121664_0	63737.Npun_R6406	1.097e-152	498.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	hxsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
GZD2_k127_4121664_2	1265505.ATUG01000003_gene681	3.023e-97	333.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2MI42@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GZD2_k127_4121664_4	1519464.HY22_02245	1.416e-50	183.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
GZD2_k127_4121664_3	449447.MAE_15570	6.849e-86	287.0	COG0473@1|root,COG0473@2|Bacteria,1G28W@1117|Cyanobacteria	1117|Cyanobacteria	C	Isocitrate isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
GZD2_k127_4124172_3	926569.ANT_12480	1.297e-54	214.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD2_k127_4124172_2	1121451.DESAM_22149	7.106e-72	251.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_4124172_5	941824.TCEL_01275	7.315e-22	99.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,24M31@186801|Clostridia,36JIG@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
GZD2_k127_4124172_4	926569.ANT_17810	5.124e-43	162.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
GZD2_k127_4124172_0	926569.ANT_17820	2.483e-232	730.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GZD2_k127_4124172_1	926569.ANT_29920	2.072e-147	479.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GZD2_k127_4129823_3	866895.HBHAL_3768	1.907e-06	53.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3NEP0@45667|Halobacillus	91061|Bacilli	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GZD2_k127_4129823_0	926569.ANT_28350	1.353e-27	113.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
GZD2_k127_4129823_1	411459.RUMOBE_03311	3.868e-20	103.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GZD2_k127_4129823_2	523845.AQXV01000034_gene396	6.188e-08	65.0	COG0455@1|root,arCOG00589@2157|Archaea,2XT20@28890|Euryarchaeota,23QK5@183939|Methanococci	183939|Methanococci	D	Belongs to the ParA family	-	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA,ParA
GZD2_k127_4132197_1	1121920.AUAU01000013_gene1701	3.28e-197	624.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_4132197_4	1232410.KI421421_gene3388	1.885e-14	83.0	COG4424@1|root,COG4424@2|Bacteria,1Q4RK@1224|Proteobacteria,42XI9@68525|delta/epsilon subdivisions,2WT6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GZD2_k127_4132197_0	1121920.AUAU01000013_gene1700	0.0	1186.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485,iIT341.HP0212	M20_dimer,Peptidase_M20
GZD2_k127_4132197_3	316274.Haur_2320	1.114e-45	171.0	COG1670@1|root,COG1670@2|Bacteria,2G9NS@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_4132197_2	497964.CfE428DRAFT_0631	4.438e-120	413.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
GZD2_k127_4132562_0	367299.JOEE01000001_gene1510	1.099e-164	533.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4FE5I@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GZD2_k127_4132562_1	1254432.SCE1572_44705	8.13e-161	515.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,42P6E@68525|delta/epsilon subdivisions,2WISH@28221|Deltaproteobacteria,2YV40@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_4132562_2	1254432.SCE1572_44710	1.388e-149	481.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42Q6K@68525|delta/epsilon subdivisions,2WM2U@28221|Deltaproteobacteria,2YX9P@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD2_k127_4132562_3	1254432.SCE1572_44715	1.561e-52	188.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GZD2_k127_4134917_3	313589.JNB_15523	1.131e-45	177.0	COG4242@1|root,COG4242@2|Bacteria,2I9QV@201174|Actinobacteria,4FIU3@85021|Intrasporangiaceae	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
GZD2_k127_4134917_1	521011.Mpal_1103	5.549e-70	244.0	COG1309@1|root,arCOG02649@2157|Archaea,2Y1BX@28890|Euryarchaeota,2NBEJ@224756|Methanomicrobia	224756|Methanomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD2_k127_4134917_4	994573.T472_0215610	2.789e-34	140.0	COG1309@1|root,COG1309@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia,36IZF@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD2_k127_4134917_0	765420.OSCT_2137	3.475e-103	349.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GZD2_k127_4134917_2	765420.OSCT_2138	2.683e-69	245.0	COG4591@1|root,COG4591@2|Bacteria,2G7ZF@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
GZD2_k127_4138700_1	926569.ANT_11820	3.349e-39	164.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
GZD2_k127_4138700_4	536019.Mesop_5573	1.595e-05	57.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,43HQY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3
GZD2_k127_4138700_2	926569.ANT_27430	3.239e-34	134.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD2_k127_4138700_3	1128421.JAGA01000001_gene2037	2.068e-26	113.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
GZD2_k127_4138700_0	926569.ANT_27450	3.997e-178	589.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
GZD2_k127_4139029_0	1040986.ATYO01000012_gene5293	2.016e-138	480.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
GZD2_k127_4141456_2	1128421.JAGA01000002_gene1557	1.149e-45	167.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
GZD2_k127_4141456_0	290397.Adeh_2071	1.047e-248	775.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
GZD2_k127_4141456_1	290397.Adeh_2070	7.459e-129	416.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GZD2_k127_4146946_1	357808.RoseRS_4538	1.862e-131	422.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_4146946_2	880072.Desac_0095	5.415e-98	330.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
GZD2_k127_4146946_3	426355.Mrad2831_0214	2.697e-36	140.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2UD5E@28211|Alphaproteobacteria,1JV34@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD2_k127_4146946_0	426117.M446_1526	9.214e-139	456.0	COG0642@1|root,COG2199@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VDSR@28211|Alphaproteobacteria,1JRF8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_7,Response_reg
GZD2_k127_4159406_0	886293.Sinac_2932	1.273e-56	207.0	COG1940@1|root,COG1940@2|Bacteria,2IZ6N@203682|Planctomycetes	203682|Planctomycetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_4159406_1	268407.PWYN_17460	1.409e-36	149.0	COG0842@1|root,COG0842@2|Bacteria,1V13R@1239|Firmicutes,4HD1H@91061|Bacilli,26U7M@186822|Paenibacillaceae	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD2_k127_4159406_2	309799.DICTH_0231	1.202e-11	72.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD2_k127_4164813_2	926569.ANT_01790	3.164e-117	387.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
GZD2_k127_4164813_1	926569.ANT_01780	1.535e-162	523.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_4164813_4	357808.RoseRS_1997	4.526e-105	361.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
GZD2_k127_4164813_3	926569.ANT_16990	8.385e-111	378.0	COG1052@1|root,COG1052@2|Bacteria,2G5K0@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GZD2_k127_4164813_0	1122221.JHVI01000018_gene1496	0.0	1115.0	COG2374@1|root,COG2374@2|Bacteria,1WM95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
GZD2_k127_4166324_1	204669.Acid345_1066	4.932e-15	81.0	COG1404@1|root,COG1409@1|root,COG3055@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JMMV@204432|Acidobacteriia	204432|Acidobacteriia	GO	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH
GZD2_k127_4166324_0	926569.ANT_15470	1.677e-215	682.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi	200795|Chloroflexi	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GZD2_k127_4171037_3	1407650.BAUB01000016_gene2371	4.173e-19	92.0	COG1597@1|root,COG1597@2|Bacteria,1G25B@1117|Cyanobacteria,1H02Z@1129|Synechococcus	1117|Cyanobacteria	I	COG1803 Methylglyoxal synthase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD2_k127_4171037_1	1305836.AXVE01000011_gene832	1.166e-60	220.0	2DBB1@1|root,2Z854@2|Bacteria,1TT9P@1239|Firmicutes,4HDSP@91061|Bacilli,26H2I@186818|Planococcaceae	91061|Bacilli	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
GZD2_k127_4171037_2	1049564.TevJSym_ad00820	8.645e-26	113.0	COG2062@1|root,COG2062@2|Bacteria,1PKQU@1224|Proteobacteria,1TKA9@1236|Gammaproteobacteria,1J754@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD2_k127_4171037_0	1340493.JNIF01000003_gene1925	1.482e-68	244.0	COG0855@1|root,COG0855@2|Bacteria,3Y2YI@57723|Acidobacteria	57723|Acidobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GZD2_k127_41741_1	926569.ANT_13870	1.204e-31	125.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GZD2_k127_41741_0	926569.ANT_13860	1.973e-43	168.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GZD2_k127_41741_2	926569.ANT_13850	1.891e-31	129.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_13850|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_41741_3	926569.ANT_13840	2.326e-19	95.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4177503_1	103690.17132493	1.591e-29	122.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1HJKZ@1161|Nostocales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4177503_3	643473.KB235930_gene3411	1.104e-18	94.0	2DM1K@1|root,31BCJ@2|Bacteria,1G6WG@1117|Cyanobacteria,1HU1Q@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4177503_2	292459.STH493	3.211e-28	129.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD2_k127_4177503_0	1128421.JAGA01000003_gene3270	1.463e-49	182.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_4178426_6	926569.ANT_19430	1.811e-11	66.0	2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi	200795|Chloroflexi	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD2_k127_4178426_5	926569.ANT_19420	1.537e-76	280.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GZD2_k127_4178426_2	926569.ANT_19410	2.134e-100	332.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GZD2_k127_4178426_4	926569.ANT_19400	3.406e-82	280.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GZD2_k127_4178426_3	926569.ANT_19390	4.292e-85	287.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GZD2_k127_4178426_0	869210.Marky_0826	5.3e-166	537.0	COG0247@1|root,COG0247@2|Bacteria,1WIPC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GZD2_k127_4180107_3	485913.Krac_11884	6.782e-58	209.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GZD2_k127_4180107_0	926569.ANT_02890	3.007e-104	342.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
GZD2_k127_4180107_4	1449063.JMLS01000001_gene4378	1.316e-38	147.0	COG0662@1|root,COG0662@2|Bacteria,1V9DQ@1239|Firmicutes,4HJK4@91061|Bacilli,26YM0@186822|Paenibacillaceae	91061|Bacilli	G	Cupin domain	algA	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_4180107_1	1313172.YM304_26130	2.403e-90	306.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
GZD2_k127_4180107_6	868864.Dester_0490	0.000146	48.0	COG2104@1|root,COG2104@2|Bacteria,2G5DW@200783|Aquificae	200783|Aquificae	H	thiamine diphosphate biosynthetic process	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
GZD2_k127_4180107_2	926569.ANT_20930	2.213e-81	285.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_4180107_5	926569.ANT_20920	2.2e-20	94.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GZD2_k127_4180475_2	926569.ANT_27200	2.734e-67	235.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
GZD2_k127_4180475_3	324602.Caur_2581	1.985e-25	110.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4180475_1	290315.Clim_1144	1.111e-70	241.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
GZD2_k127_4180475_0	926550.CLDAP_06140	6.53e-162	515.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GZD2_k127_419691_6	1120965.AUBV01000001_gene3341	8.43e-09	61.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RTK@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
GZD2_k127_419691_0	557599.MKAN_03700	2.19e-69	244.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,2369X@1762|Mycobacteriaceae	201174|Actinobacteria	S	short-chain dehydrogenase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GZD2_k127_419691_1	351160.RCIX2633	3.251e-65	234.0	COG0604@1|root,arCOG01458@2157|Archaea,2XURG@28890|Euryarchaeota,2N9N6@224756|Methanomicrobia	224756|Methanomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
GZD2_k127_419691_3	234267.Acid_0055	4.176e-42	162.0	2AY4N@1|root,31Q6J@2|Bacteria,3Y7H6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_419691_4	1122138.AQUZ01000018_gene7441	1.271e-14	83.0	COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria,4DVNY@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
GZD2_k127_4200728_1	926569.ANT_14490	9.562e-56	196.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GZD2_k127_4200728_0	926550.CLDAP_00970	3.395e-155	510.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD2_k127_4202140_2	926569.ANT_27460	2.006e-14	78.0	COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi	200795|Chloroflexi	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
GZD2_k127_4202140_0	926569.ANT_02700	4.007e-55	195.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GZD2_k127_4202140_1	926569.ANT_08910	8.152e-22	99.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
GZD2_k127_4207475_2	926569.ANT_00390	1.998e-57	205.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
GZD2_k127_4207475_4	926569.ANT_00380	1.688e-31	132.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4207475_0	926569.ANT_00370	5.66e-78	293.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GZD2_k127_4207475_3	926569.ANT_00360	1.603e-34	141.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4207475_1	926569.ANT_00350	8.325e-59	214.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4207475_6	592015.HMPREF1705_01944	1.203e-05	49.0	COG2185@1|root,COG2185@2|Bacteria,3TAYI@508458|Synergistetes	508458|Synergistetes	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GZD2_k127_4212567_2	1380390.JIAT01000010_gene3534	8.969e-36	144.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
GZD2_k127_4212567_1	1173264.KI913949_gene1051	3.391e-36	140.0	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria,1HBUI@1150|Oscillatoriales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_4212567_0	1120792.JAFV01000001_gene1773	4.625e-107	357.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,36YMH@31993|Methylocystaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase central domain	Sardh	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GZD2_k127_4221748_0	926569.ANT_07040	9.49e-137	443.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
GZD2_k127_4221748_3	926569.ANT_07030	4.209e-39	150.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
GZD2_k127_4221748_2	316274.Haur_0049	4.421e-69	241.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_4221748_1	316274.Haur_0048	8.33e-93	314.0	COG1235@1|root,COG1235@2|Bacteria,2G833@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GZD2_k127_4221748_5	926550.CLDAP_10950	0.0003189	45.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
GZD2_k127_4227452_4	404380.Gbem_2014	1.158e-41	160.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4227452_6	204669.Acid345_3970	4.498e-21	98.0	2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4227452_3	867845.KI911784_gene1337	3.392e-67	241.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi,375B8@32061|Chloroflexia	32061|Chloroflexia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GZD2_k127_4227452_7	471853.Bcav_3670	1.484e-18	92.0	COG1162@1|root,COG1162@2|Bacteria,2IMZI@201174|Actinobacteria	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
GZD2_k127_4227452_1	926569.ANT_04320	2.141e-119	389.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_4227452_2	926569.ANT_30350	7.28e-69	254.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4227452_0	926569.ANT_30340	1.392e-123	410.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GZD2_k127_4228422_0	42256.RradSPS_0358	3.926e-219	702.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GZD2_k127_4228422_1	329726.AM1_6084	1.43e-26	111.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4230429_1	314345.SPV1_10019	4.507e-80	294.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
GZD2_k127_4230429_2	937777.Deipe_2413	1.093e-33	150.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
GZD2_k127_4230429_0	926569.ANT_08920	1.026e-92	311.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD2_k127_4234960_3	246197.MXAN_6602	3.818e-19	89.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
GZD2_k127_4234960_1	1047013.AQSP01000122_gene2256	5.7e-82	287.0	COG0624@1|root,COG0624@2|Bacteria,2NQWS@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD2_k127_4234960_0	324602.Caur_2791	7.873e-105	348.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,375QT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GZD2_k127_4234960_2	1123368.AUIS01000003_gene1806	2.716e-39	149.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
GZD2_k127_424062_1	234267.Acid_4539	2.734e-133	436.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
GZD2_k127_424062_2	926569.ANT_24800	6.407e-60	212.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
GZD2_k127_424062_0	926569.ANT_24790	1.029e-191	617.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi	200795|Chloroflexi	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
GZD2_k127_4245291_3	926569.ANT_19820	1.99e-45	172.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GZD2_k127_4245291_2	316274.Haur_3812	1.584e-66	244.0	COG0793@1|root,COG0793@2|Bacteria,2GAAX@200795|Chloroflexi,374TM@32061|Chloroflexia	32061|Chloroflexia	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
GZD2_k127_4245291_1	304371.MCP_0966	1.261e-66	237.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GZD2_k127_4245291_4	926569.ANT_28920	3.637e-35	146.0	28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi	926569.ANT_28920|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4245291_0	926550.CLDAP_24920	2.458e-122	400.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_4245291_5	926569.ANT_28020	1.333e-19	93.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
GZD2_k127_4248264_0	485916.Dtox_2632	1.034e-51	187.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GZD2_k127_4248264_3	1121957.ATVL01000006_gene3440	9.88e-35	137.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
GZD2_k127_4248264_1	710421.Mycch_1790	1.483e-50	189.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GZD2_k127_4248264_2	926569.ANT_31070	2.78e-40	156.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
GZD2_k127_4255232_1	240016.ABIZ01000001_gene3242	2.122e-84	286.0	COG0500@1|root,COG2226@2|Bacteria,46TDK@74201|Verrucomicrobia,2IUIX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_4255232_3	67257.JODR01000014_gene5811	1.792e-72	262.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_4255232_0	316274.Haur_3664	2.379e-241	754.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Arabinose_Iso_C,Arabinose_Isome
GZD2_k127_4255232_2	521045.Kole_0991	1.161e-75	258.0	COG0473@1|root,COG0473@2|Bacteria,2GCZJ@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73	ko:K00052,ko:K07246	ko00290,ko00630,ko00650,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00630,map00650,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00215,R00994,R01751,R02545,R04426,R06180,R10052	RC00084,RC00105,RC00417,RC00594,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GZD2_k127_4256836_2	518766.Rmar_1393	2.403e-10	67.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
GZD2_k127_4256836_0	235909.GK3229	5.568e-39	149.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,1WGJY@129337|Geobacillus	91061|Bacilli	J	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
GZD2_k127_4271185_2	926569.ANT_14730	3.818e-75	258.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GZD2_k127_4271185_3	306281.AJLK01000110_gene2672	2.178e-43	162.0	COG0614@1|root,COG0614@2|Bacteria,1G7SF@1117|Cyanobacteria,1JITM@1189|Stigonemataceae	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GZD2_k127_4271185_1	926569.ANT_14740	7.654e-135	438.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GZD2_k127_4271185_0	926569.ANT_14760	1.67e-257	808.0	COG1506@1|root,COG1506@2|Bacteria,2G5Z2@200795|Chloroflexi	200795|Chloroflexi	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GZD2_k127_4277256_1	926569.ANT_11190	2.27e-25	106.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
GZD2_k127_4277256_2	90813.JQMT01000001_gene636	1.094e-20	103.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,460V5@72273|Thiotrichales	72273|Thiotrichales	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GZD2_k127_4277256_0	926569.ANT_11210	6.466e-130	424.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GZD2_k127_4287912_4	1380391.JIAS01000015_gene369	2.324e-52	195.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
GZD2_k127_4287912_3	1298880.AUEV01000002_gene1744	9.668e-79	273.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria	201174|Actinobacteria	M	Choline ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
GZD2_k127_4287912_0	639283.Snov_2172	4.752e-132	430.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3EYGH@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
GZD2_k127_4287912_2	1097668.BYI23_C006370	1.045e-84	290.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2VMSC@28216|Betaproteobacteria,1K3MI@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GZD2_k127_4287912_1	926569.ANT_31320	1.914e-85	286.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
GZD2_k127_4288559_0	118168.MC7420_8279	5.406e-188	606.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
GZD2_k127_4288559_1	1173027.Mic7113_1369	3.668e-54	207.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
GZD2_k127_4288559_2	1487953.JMKF01000042_gene2678	1.23e-18	94.0	COG1672@1|root,COG2319@1|root,COG4249@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_C14,TIR_2,WD40
GZD2_k127_4295845_2	1242864.D187_001132	2.972e-22	113.0	COG2273@1|root,COG2273@2|Bacteria,1RANY@1224|Proteobacteria,437CZ@68525|delta/epsilon subdivisions,2X2IX@28221|Deltaproteobacteria,2Z2SU@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
GZD2_k127_4295845_1	485913.Krac_9959	5.127e-146	490.0	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria,2G8G7@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 5	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
GZD2_k127_4295845_0	926569.ANT_04950	5.24e-186	589.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
GZD2_k127_4310427_3	1123371.ATXH01000018_gene1376	1.775e-32	130.0	COG1028@1|root,COG1028@2|Bacteria,2GH4K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD2_k127_4310427_2	926569.ANT_20710	3.352e-44	168.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
GZD2_k127_4310427_0	926569.ANT_20700	5.05e-175	563.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GZD2_k127_4310427_1	926569.ANT_14790	1.141e-57	205.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GZD2_k127_4311682_2	706587.Desti_4720	4.081e-121	394.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GZD2_k127_4311682_0	706587.Desti_4719	7.386e-140	452.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GZD2_k127_4311682_4	706587.Desti_4721	6.029e-28	115.0	2DZFA@1|root,32V98@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4311682_1	357808.RoseRS_1484	6.98e-139	448.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_4311682_3	926569.ANT_22510	3.737e-92	311.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD2_k127_4316965_2	65393.PCC7424_0063	3.199e-29	117.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3KJY9@43988|Cyanothece	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
GZD2_k127_4316965_0	287.DR97_6308	5.67e-36	151.0	COG3594@1|root,COG3594@2|Bacteria,1RGHJ@1224|Proteobacteria,1SSVD@1236|Gammaproteobacteria,1YHHR@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Acyltransferase family	pslL	-	-	ko:K21005	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Acyl_transf_3
GZD2_k127_4316965_1	926550.CLDAP_02720	5.05e-34	134.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GZD2_k127_4324170_7	926569.ANT_28020	6.745e-25	109.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
GZD2_k127_4324170_6	754436.JCM19237_3500	1.818e-35	140.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XXB1@135623|Vibrionales	135623|Vibrionales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GZD2_k127_4324170_0	926569.ANT_19920	2.813e-96	327.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
GZD2_k127_4324170_4	926569.ANT_19930	5.577e-74	260.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GZD2_k127_4324170_5	42256.RradSPS_0073	1.478e-42	168.0	COG0679@1|root,COG0679@2|Bacteria,2H081@201174|Actinobacteria	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
GZD2_k127_4324170_2	926569.ANT_19940	1.06e-80	287.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
GZD2_k127_4324170_9	28072.Nos7524_0362	1.218e-15	80.0	COG1254@1|root,COG1254@2|Bacteria,1G7UW@1117|Cyanobacteria,1HP34@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GZD2_k127_4324170_1	1304880.JAGB01000001_gene540	1.006e-92	310.0	COG1028@1|root,COG1028@2|Bacteria,1TPTY@1239|Firmicutes,24HN8@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_4324170_3	935948.KE386494_gene165	4.293e-77	263.0	COG3828@1|root,COG3828@2|Bacteria,1V459@1239|Firmicutes,25DAB@186801|Clostridia	186801|Clostridia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
GZD2_k127_4324170_8	1128421.JAGA01000002_gene375	2.153e-18	84.0	COG2003@1|root,COG2003@2|Bacteria,2NPI9@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
GZD2_k127_4332768_0	926569.ANT_03350	2.537e-121	396.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GZD2_k127_4332768_3	1382358.JHVN01000012_gene2083	1.858e-14	85.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,21V8C@150247|Anoxybacillus	91061|Bacilli	EGP	Nucleoside H+ symporter	ywbF	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
GZD2_k127_4332768_1	1521187.JPIM01000129_gene3616	3.068e-94	314.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,377EF@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GZD2_k127_4332768_2	163908.KB235896_gene1145	2.198e-18	85.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1G0DN@1117|Cyanobacteria,1HIEI@1161|Nostocales	1117|Cyanobacteria	G	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
GZD2_k127_4334061_16	1394178.AWOO02000007_gene3240	5.297e-07	56.0	COG3568@1|root,COG3568@2|Bacteria,2IK74@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
GZD2_k127_4334061_10	926550.CLDAP_21910	4.192e-56	198.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GZD2_k127_4334061_13	1144343.PMI41_01128	3.547e-41	156.0	2DBX9@1|root,2ZBN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4334061_14	926550.CLDAP_18620	1.567e-33	134.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
GZD2_k127_4334061_4	926569.ANT_31090	1.836e-106	353.0	COG2962@1|root,COG2962@2|Bacteria,2G6C2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM RarD protein, DMT superfamily transporter	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
GZD2_k127_4334061_2	452637.Oter_0984	5.567e-124	406.0	COG0451@1|root,COG0451@2|Bacteria,46UA1@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_4334061_7	706587.Desti_5093	3.378e-94	339.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GZD2_k127_4334061_5	867845.KI911784_gene3052	3.036e-103	362.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
GZD2_k127_4334061_3	926569.ANT_03090	2.099e-109	364.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GZD2_k127_4334061_6	83406.HDN1F_13890	3.82e-102	341.0	COG0382@1|root,COG0382@2|Bacteria,1RA0E@1224|Proteobacteria	1224|Proteobacteria	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GZD2_k127_4334061_8	713586.KB900536_gene584	8.21e-78	269.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1WX56@135613|Chromatiales	135613|Chromatiales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
GZD2_k127_4334061_1	666685.R2APBS1_3641	2.053e-142	461.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1X42C@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	-	-	4.2.3.152	ko:K19969	ko00525,ko01130,map00525,map01130	M00814,M00815	R10937	RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
GZD2_k127_4334061_11	83406.HDN1F_13860	1.742e-48	178.0	COG1854@1|root,COG1854@2|Bacteria	2|Bacteria	H	S-ribosylhomocysteine lyase activity	luxS	GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
GZD2_k127_4334061_0	1163409.UUA_15943	6.604e-169	539.0	COG1082@1|root,COG1082@2|Bacteria,1N95R@1224|Proteobacteria	1224|Proteobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GZD2_k127_4334061_12	926569.ANT_03100	1.807e-48	188.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4334061_15	1122611.KB903988_gene7173	1.216e-10	64.0	2EFVT@1|root,339N0@2|Bacteria,2GWUH@201174|Actinobacteria,4EKY7@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4334061_9	926550.CLDAP_17710	5.158e-71	245.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GZD2_k127_4340671_2	326427.Cagg_3472	0.000173	47.0	COG2270@1|root,COG2270@2|Bacteria,2G8AF@200795|Chloroflexi,3771A@32061|Chloroflexia	32061|Chloroflexia	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_4340671_0	479434.Sthe_2033	1.376e-100	342.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_4340671_1	1128421.JAGA01000002_gene1392	1.473e-86	300.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
GZD2_k127_4340754_1	926569.ANT_27700	3.333e-102	335.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
GZD2_k127_4340754_0	745776.DGo_CA2326	1.961e-185	602.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	dMI1	-	3.1.4.46	ko:K01126,ko:K10716	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Castor_Poll_mid,TrkA_N
GZD2_k127_4406293_0	504832.OCAR_5287	4.036e-137	445.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,3JRTE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	fdsB	-	1.12.1.2,1.6.5.3	ko:K00124,ko:K00335,ko:K18005	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
GZD2_k127_4406293_3	926569.ANT_18930	2.452e-61	232.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
GZD2_k127_4406293_2	926550.CLDAP_05930	8.584e-93	309.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
GZD2_k127_4406293_1	926550.CLDAP_06400	2.528e-106	350.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GZD2_k127_4406563_3	857087.Metme_3931	3.275e-23	102.0	COG0577@1|root,COG0577@2|Bacteria,1PJZX@1224|Proteobacteria,1RU56@1236|Gammaproteobacteria,1XDTW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_4406563_4	381666.H16_A2749	0.0005173	52.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2VKCR@28216|Betaproteobacteria,1K02P@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Major facilitator superfamily	-	-	-	ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.7	-	-	MFS_1
GZD2_k127_4406563_2	1123073.KB899245_gene113	1.636e-25	111.0	COG0454@1|root,COG0456@2|Bacteria,1MYBJ@1224|Proteobacteria,1SXQX@1236|Gammaproteobacteria,1X6KP@135614|Xanthomonadales	135614|Xanthomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4406563_1	1173020.Cha6605_0968	1.268e-131	430.0	COG2267@1|root,COG2267@2|Bacteria,1G771@1117|Cyanobacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
GZD2_k127_4406563_0	926569.ANT_24960	0.0	1034.0	COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi	200795|Chloroflexi	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
GZD2_k127_4407036_1	997296.PB1_11914	1.209e-44	169.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,1ZCQS@1386|Bacillus	91061|Bacilli	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4407036_3	1286170.RORB6_07930	5.813e-05	54.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,1S6DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD2_k127_4407036_2	1210884.HG799474_gene15133	1.257e-08	60.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
GZD2_k127_441588_1	1128421.JAGA01000001_gene2070	1.964e-138	454.0	COG0366@1|root,COG0366@2|Bacteria,2NQFG@2323|unclassified Bacteria	2|Bacteria	G	Alpha-amylase domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	iLJ478.TM1840	Alpha-amylase,DUF1945,DUF3459
GZD2_k127_441588_0	649638.Trad_2961	3.75e-158	516.0	COG0366@1|root,COG0366@2|Bacteria,1WIU5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
GZD2_k127_4425291_2	448385.sce4530	5.935e-37	145.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,4376W@68525|delta/epsilon subdivisions,2X277@28221|Deltaproteobacteria,2Z1SB@29|Myxococcales	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
GZD2_k127_4425291_0	401053.AciPR4_2252	9.115e-81	292.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GZD2_k127_4425291_1	485913.Krac_1738	2.3e-69	248.0	COG1357@1|root,COG1357@2|Bacteria,2G7HW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD2_k127_4425291_3	1121272.KB903283_gene5019	1.276e-07	60.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
GZD2_k127_4447485_6	1089544.KB912942_gene1696	2.411e-57	207.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
GZD2_k127_4447485_3	880073.Calab_0286	6.409e-133	432.0	COG1294@1|root,COG1294@2|Bacteria,2NS31@2323|unclassified Bacteria	2|Bacteria	C	PFAM Cytochrome bd ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120	Cyt_bd_oxida_II
GZD2_k127_4447485_2	880073.Calab_1809	8.139e-214	674.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_4447485_0	765420.OSCT_1692	4.732e-256	831.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi	200795|Chloroflexi	CO	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
GZD2_k127_4447485_1	926569.ANT_09360	2.522e-217	681.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GZD2_k127_4447485_4	926569.ANT_09370	3.757e-84	291.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
GZD2_k127_4447485_5	926569.ANT_18900	2.292e-64	229.0	COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi	200795|Chloroflexi	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
GZD2_k127_4449618_0	479434.Sthe_1490	2.122e-111	370.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GZD2_k127_4449618_6	926569.ANT_03610	7.625e-58	221.0	COG1708@1|root,COG1708@2|Bacteria,2G7IZ@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4111)	-	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
GZD2_k127_4449618_7	485913.Krac_3330	5.669e-37	158.0	COG1708@1|root,COG1708@2|Bacteria,2G7IZ@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4111)	-	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
GZD2_k127_4449618_3	697281.Mahau_0729	1.164e-79	273.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,250X6@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4449618_4	926569.ANT_03810	1.247e-77	274.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
GZD2_k127_4449618_8	1205910.B005_1046	6.132e-23	111.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4EFQT@85012|Streptosporangiales	201174|Actinobacteria	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
GZD2_k127_4449618_2	926569.ANT_03800	3.278e-98	328.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GZD2_k127_4449618_1	926569.ANT_03790	3.606e-99	329.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GZD2_k127_4449618_5	926569.ANT_03780	1.246e-65	230.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	2|Bacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
GZD2_k127_4450598_2	865861.AZSU01000003_gene2262	1.923e-08	62.0	COG1181@1|root,COG1181@2|Bacteria,1TRW2@1239|Firmicutes,24F2R@186801|Clostridia,36IY4@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GZD2_k127_4450598_0	485916.Dtox_2814	4.998e-137	452.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
GZD2_k127_4450598_1	311424.DhcVS_1405	1.647e-36	156.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2G7Y4@200795|Chloroflexi,34DMA@301297|Dehalococcoidia	301297|Dehalococcoidia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
GZD2_k127_4450598_3	1179773.BN6_36430	0.0002234	50.0	2EQPB@1|root,33I99@2|Bacteria,2IKF5@201174|Actinobacteria,4E6A5@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4470305_0	926569.ANT_14560	1.883e-61	221.0	COG0790@1|root,COG3359@1|root,COG0790@2|Bacteria,COG3359@2|Bacteria,2G6TK@200795|Chloroflexi	200795|Chloroflexi	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
GZD2_k127_4470305_2	335541.Swol_1795	1.88e-08	61.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24NE7@186801|Clostridia	186801|Clostridia	T	STAS domain	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD2_k127_4470305_3	1184607.AUCHE_04_00560	0.0001298	49.0	COG1366@1|root,COG1366@2|Bacteria,2HPDK@201174|Actinobacteria,4F787@85018|Dermatophilaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
GZD2_k127_4470305_1	926569.ANT_29070	2.845e-32	132.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GZD2_k127_4472785_0	929556.Solca_4177	2.236e-131	422.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GZD2_k127_4472785_1	266117.Rxyl_0908	3.863e-53	190.0	COG2050@1|root,COG2050@2|Bacteria,2IR9T@201174|Actinobacteria,4CTI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD2_k127_4472785_2	158190.SpiGrapes_1791	3.504e-24	108.0	COG1102@1|root,COG1102@2|Bacteria,2J5C1@203691|Spirochaetes	203691|Spirochaetes	F	Phospholipid-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
GZD2_k127_447704_2	457429.ABJI02000796_gene4438	9.479e-17	83.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_447704_1	330084.JNYZ01000032_gene5514	1.153e-32	131.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
GZD2_k127_447704_0	290397.Adeh_2304	0.0	1158.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_447704_3	479434.Sthe_2304	7.297e-10	64.0	COG0500@1|root,COG2226@2|Bacteria,2G798@200795|Chloroflexi,27Z7K@189775|Thermomicrobia	189775|Thermomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4484714_1	459349.CLOAM1631	2.361e-53	193.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
GZD2_k127_4484714_3	926569.ANT_14440	8.346e-48	178.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
GZD2_k127_4484714_0	926569.ANT_14430	1.017e-116	384.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
GZD2_k127_4484714_2	926550.CLDAP_12770	9.356e-51	190.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GZD2_k127_4484714_5	926569.ANT_04680	4.915e-27	115.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD2_k127_4484714_4	521045.Kole_0517	2.903e-34	133.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
GZD2_k127_4487954_0	1121382.JQKG01000026_gene2919	3.744e-139	446.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GZD2_k127_4487954_3	1121918.ARWE01000001_gene3196	1.48e-05	54.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43CY0@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
GZD2_k127_4487954_2	1173029.JH980292_gene614	1.689e-12	77.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GZD2_k127_4487954_1	316274.Haur_1208	2.173e-42	158.0	COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi,375D5@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
GZD2_k127_4499923_0	926569.ANT_01090	3.734e-121	393.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi	200795|Chloroflexi	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GZD2_k127_4499923_5	1403819.BATR01000075_gene2193	3.915e-09	64.0	COG3779@1|root,COG3779@2|Bacteria,46X04@74201|Verrucomicrobia,2IW8T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
GZD2_k127_4499923_1	485913.Krac_8744	5.584e-57	201.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GZD2_k127_4499923_3	926550.CLDAP_11670	4.692e-33	134.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_4499923_2	926569.ANT_09400	3.983e-43	168.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GZD2_k127_4499923_4	316274.Haur_3621	6.94e-31	122.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,3751U@32061|Chloroflexia	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
GZD2_k127_4501293_4	1162668.LFE_2242	3.201e-14	76.0	COG0438@1|root,COG0438@2|Bacteria,3J165@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_4501293_0	1123060.JONP01000007_gene5042	1.116e-121	405.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GZD2_k127_4501293_2	1268622.AVS7_03901	3.498e-21	94.0	COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GZD2_k127_4501293_3	937777.Deipe_2405	6.298e-16	84.0	2ECKJ@1|root,33KDJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4501293_5	933115.GPDM_15404	1.943e-11	71.0	COG4430@1|root,COG4430@2|Bacteria,1UNCJ@1239|Firmicutes,4IU9W@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GZD2_k127_4501293_1	485913.Krac_2664	3.702e-44	169.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4503705_4	926569.ANT_06090	7.231e-33	139.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,WXG100
GZD2_k127_4503705_0	926569.ANT_06990	3.942e-198	629.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GZD2_k127_4503705_1	926569.ANT_07650	5.247e-166	531.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_4503705_2	926569.ANT_07660	3.176e-99	327.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_4503705_3	926569.ANT_07670	6.824e-73	257.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD2_k127_4507601_2	479434.Sthe_2058	3.313e-59	213.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,27XYT@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
GZD2_k127_4507601_1	429009.Adeg_1032	1.01e-73	263.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42FW0@68295|Thermoanaerobacterales	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_4507601_3	1396418.BATQ01000001_gene1266	1.675e-19	102.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,46UUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,S6PP
GZD2_k127_4507601_0	525904.Tter_0222	7.158e-114	379.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GZD2_k127_4511854_0	926550.CLDAP_35260	1.258e-81	275.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_4511854_3	990285.RGCCGE502_00110	1.072e-35	148.0	COG0030@1|root,COG0030@2|Bacteria,1QVEH@1224|Proteobacteria,2TYNG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
GZD2_k127_4511854_6	649831.L083_3499	2.014e-05	52.0	2EG61@1|root,339XX@2|Bacteria,2IMU8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4511854_5	357808.RoseRS_1567	1.194e-08	66.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5
GZD2_k127_4511854_7	330214.NIDE2630	0.000255	47.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	M1-674	-	3.4.21.107	ko:K01173,ko:K04771	ko01503,ko02020,ko04210,map01503,map02020,map04210	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03029,ko03110	-	-	-	Trypsin,Trypsin_2
GZD2_k127_4511854_1	357808.RoseRS_1569	1.292e-68	244.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
GZD2_k127_4511854_2	649831.L083_3500	2.745e-63	231.0	COG3629@1|root,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GZD2_k127_4521665_0	913865.DOT_4317	1.67e-97	323.0	COG5361@1|root,COG5361@2|Bacteria,1TRC7@1239|Firmicutes,24AHD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
GZD2_k127_4521665_1	1356854.N007_08225	4.885e-82	277.0	COG5361@1|root,COG5361@2|Bacteria,1V2QH@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1254
GZD2_k127_4521665_2	479434.Sthe_2591	5.153e-68	245.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GZD2_k127_4529961_8	497321.C664_04277	1.911e-10	65.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2VIZS@28216|Betaproteobacteria,2KYDN@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_4529961_4	1382306.JNIM01000001_gene2204	6.069e-37	144.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
GZD2_k127_4529961_7	710686.Mycsm_02714	5.728e-17	85.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria,23C1I@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
GZD2_k127_4529961_9	203124.Tery_2061	2.203e-07	60.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,FGE-sulfatase,Peptidase_C14
GZD2_k127_4529961_0	861299.J421_6182	6.309e-174	554.0	COG1819@1|root,COG1819@2|Bacteria,1ZV4F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
GZD2_k127_4529961_3	1476583.DEIPH_ctg040orf0015	3.154e-38	145.0	2DNXR@1|root,32ZPP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
GZD2_k127_4529961_2	700598.Niako_2991	2.893e-40	154.0	COG3832@1|root,COG3832@2|Bacteria,4NUFM@976|Bacteroidetes,1IY2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD2_k127_4529961_5	1123073.KB899244_gene449	2.473e-36	141.0	COG0251@1|root,COG0251@2|Bacteria,1N917@1224|Proteobacteria,1SZKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	ko:K10013	ko02010,map02010	M00225	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	Ribonuc_L-PSP
GZD2_k127_4529961_1	449447.MAE_20230	1.138e-101	334.0	COG3506@1|root,COG3506@2|Bacteria,1G5CJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
GZD2_k127_4529961_6	383372.Rcas_3953	2.885e-35	145.0	COG4632@1|root,COG4632@2|Bacteria,2G8RE@200795|Chloroflexi,375J8@32061|Chloroflexia	32061|Chloroflexia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GZD2_k127_4532770_1	926569.ANT_15850	1.084e-33	146.0	COG4745@1|root,COG4745@2|Bacteria,2G9RB@200795|Chloroflexi	200795|Chloroflexi	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4532770_0	926550.CLDAP_30390	1.974e-64	240.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
GZD2_k127_4555472_8	1089544.KB912942_gene1408	1.167e-19	104.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4E289@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_4555472_0	323259.Mhun_0636	1.156e-248	800.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,2N9F9@224756|Methanomicrobia	224756|Methanomicrobia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GZD2_k127_4555472_4	1163671.JAGI01000003_gene515	1.582e-58	211.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,36VPU@31979|Clostridiaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD2_k127_4555472_3	383372.Rcas_2661	2.01e-74	256.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,377FQ@32061|Chloroflexia	32061|Chloroflexia	C	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD2_k127_4555472_1	439235.Dalk_3400	1.54e-123	423.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WMP9@28221|Deltaproteobacteria,2MPMH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GZD2_k127_4555472_5	118173.KB235914_gene1399	6.458e-52	210.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_4555472_7	1300345.LF41_612	3.417e-33	135.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1X61F@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_4555472_2	316274.Haur_1524	4.536e-102	350.0	COG3711@1|root,COG3711@2|Bacteria	2|Bacteria	K	transcriptional antiterminator	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
GZD2_k127_4555472_6	235909.GK1948	2.513e-49	178.0	COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1WFWV@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.197	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIC,PTS_IIB
GZD2_k127_4568604_1	768710.DesyoDRAFT_4220	2.244e-56	212.0	COG5598@1|root,COG5598@2|Bacteria,1V335@1239|Firmicutes,24GX0@186801|Clostridia,26435@186807|Peptococcaceae	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
GZD2_k127_4568604_0	926550.CLDAP_01290	5.074e-114	379.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_45732_6	926550.CLDAP_11300	2.155e-26	110.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD2_k127_45732_3	765420.OSCT_0618	1.936e-101	336.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi,374Z9@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD2_k127_45732_4	383372.Rcas_1896	1.78e-96	321.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD2_k127_45732_1	756067.MicvaDRAFT_1623	5.694e-123	408.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria,1H80W@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
GZD2_k127_45732_2	1173027.Mic7113_0201	1.305e-120	398.0	COG0559@1|root,COG0559@2|Bacteria,1G3S0@1117|Cyanobacteria,1H9UM@1150|Oscillatoriales	1117|Cyanobacteria	E	transport system permease	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD2_k127_45732_0	32057.KB217478_gene1555	7.443e-135	450.0	COG4177@1|root,COG4177@2|Bacteria,1G20I@1117|Cyanobacteria,1HJC8@1161|Nostocales	1117|Cyanobacteria	U	Belongs to the binding-protein-dependent transport system permease family	natC	-	-	ko:K01998,ko:K11955	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
GZD2_k127_45732_5	402777.KB235903_gene857	8.367e-96	318.0	COG0411@1|root,COG0411@2|Bacteria,1GR1B@1117|Cyanobacteria,1HH7N@1150|Oscillatoriales	1117|Cyanobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD2_k127_4585224_5	262724.TT_C0752	5.47e-61	214.0	COG0247@1|root,COG0247@2|Bacteria,1WIPC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GZD2_k127_4585224_7	479434.Sthe_3187	5.8e-34	136.0	COG3871@1|root,COG3871@2|Bacteria,2G9DN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD2_k127_4585224_9	1347087.CBYO010000022_gene3643	1.378e-19	93.0	2E4BN@1|root,32Z79@2|Bacteria,1VQQV@1239|Firmicutes,4HRU8@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4585224_8	1379698.RBG1_1C00001G1687	7.991e-31	126.0	2DNQ8@1|root,32YJ3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4585224_0	671143.DAMO_0966	6.426e-141	456.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GZD2_k127_4585224_6	1499967.BAYZ01000118_gene3301	3.276e-43	161.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
GZD2_k127_4585224_1	1499967.BAYZ01000118_gene3300	1.385e-138	450.0	COG1454@1|root,COG1454@2|Bacteria,2NQ5W@2323|unclassified Bacteria	2|Bacteria	C	Iron-containing alcohol dehydrogenase	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714,ko:K13954	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
GZD2_k127_4585224_3	314230.DSM3645_13525	4.967e-109	366.0	COG0156@1|root,COG0318@1|root,COG0156@2|Bacteria,COG0318@2|Bacteria,2IXBN@203682|Planctomycetes	203682|Planctomycetes	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
GZD2_k127_4585224_2	926569.ANT_01810	3.406e-132	429.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_4585224_4	926569.ANT_28950	7.689e-67	231.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
GZD2_k127_4648344_1	868595.Desca_0981	3.497e-80	272.0	COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,24DQG@186801|Clostridia,264HT@186807|Peptococcaceae	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD2_k127_4648344_2	926569.ANT_04220	2.938e-35	147.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
GZD2_k127_4648344_0	926569.ANT_04230	8.209e-102	339.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GZD2_k127_4653216_6	1122138.AQUZ01000027_gene879	1.493e-31	130.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
GZD2_k127_4653216_2	926560.KE387023_gene2174	6.991e-84	290.0	COG0454@1|root,COG0454@2|Bacteria,1WJYD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4653216_0	383372.Rcas_0299	2.818e-101	342.0	COG1168@1|root,COG1168@2|Bacteria,2G614@200795|Chloroflexi,375GA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase, class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_4653216_3	479434.Sthe_2389	6.424e-77	263.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
GZD2_k127_4653216_5	1166018.FAES_2256	8.534e-61	216.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,47PEW@768503|Cytophagia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD2_k127_4653216_7	1463920.JOGB01000073_gene1399	2.952e-16	81.0	2FE2T@1|root,3462W@2|Bacteria,2GS9J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4653216_4	926550.CLDAP_15070	8.683e-65	231.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
GZD2_k127_4653216_1	926550.CLDAP_29060	4.544e-99	332.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
GZD2_k127_4663460_6	1038859.AXAU01000002_gene317	1.25e-32	130.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Conserved TM helix repeat-containing protein	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
GZD2_k127_4663460_5	751945.Theos_1561	5.115e-40	151.0	COG4401@1|root,COG4401@2|Bacteria,1WJZD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GZD2_k127_4663460_0	926569.ANT_01870	2.308e-143	462.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GZD2_k127_4663460_4	926569.ANT_01880	2.4e-60	220.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
GZD2_k127_4663460_1	1120973.AQXL01000134_gene1554	2.738e-133	437.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GZD2_k127_4663460_3	926569.ANT_01900	1.044e-65	234.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
GZD2_k127_4663460_2	926569.ANT_01910	2.615e-83	281.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GZD2_k127_4665114_1	386456.JQKN01000001_gene1802	1.922e-85	316.0	COG0642@1|root,COG3413@1|root,arCOG02348@1|root,arCOG02350@1|root,arCOG03567@1|root,arCOG06712@1|root,arCOG02278@2157|Archaea,arCOG02348@2157|Archaea,arCOG02350@2157|Archaea,arCOG02358@2157|Archaea,arCOG03567@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,HisKA_4TM,MEDS,PAS,PAS_3,PAS_4,PAS_9
GZD2_k127_4665114_2	485913.Krac_6669	3.008e-57	207.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_4665114_3	221288.JH992901_gene1163	4.425e-21	103.0	COG3039@1|root,COG3039@2|Bacteria,1G3IA@1117|Cyanobacteria,1JJJQ@1189|Stigonemataceae	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
GZD2_k127_4665114_0	1035308.AQYY01000002_gene632	0.0	1829.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,260KE@186807|Peptococcaceae	186801|Clostridia	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GZD2_k127_4704032_14	1380355.JNIJ01000056_gene159	1.125e-11	66.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria,3JQZM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis protein	rfbE	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GZD2_k127_4704032_8	404380.Gbem_1627	1.291e-35	153.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
GZD2_k127_4704032_5	926569.ANT_25890	3.842e-70	243.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GZD2_k127_4704032_9	926569.ANT_15900	1.207e-26	122.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GZD2_k127_4704032_0	269800.Tfu_0829	1.143e-226	717.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4EGDX@85012|Streptosporangiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
GZD2_k127_4704032_6	926569.ANT_22770	1.565e-56	204.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
GZD2_k127_4704032_7	926569.ANT_30190	3.73e-40	152.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GZD2_k127_4704032_13	485913.Krac_2206	7.149e-15	81.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD2_k127_4704032_11	1461577.CCMH01000037_gene120	4.237e-16	87.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD2_k127_4704032_3	358681.BBR47_51080	5.685e-81	278.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,26RI0@186822|Paenibacillaceae	91061|Bacilli	E	generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GZD2_k127_4704032_4	926569.ANT_01690	1.718e-74	255.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
GZD2_k127_4704032_10	511051.CSE_10050	1.284e-20	100.0	2BVWN@1|root,33U5I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4704032_2	324602.Caur_2204	2.457e-90	311.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_4704032_1	926569.ANT_01680	1.571e-222	701.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
GZD2_k127_4709622_4	765420.OSCT_0032	8.532e-20	93.0	COG1366@1|root,COG1366@2|Bacteria,2G9G0@200795|Chloroflexi,377V1@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
GZD2_k127_4709622_1	765420.OSCT_0033	6.802e-113	383.0	COG1208@1|root,COG2148@1|root,COG1208@2|Bacteria,COG2148@2|Bacteria,2G65W@200795|Chloroflexi,374YB@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Hexapep,NTP_transferase
GZD2_k127_4709622_0	867845.KI911784_gene1647	3.198e-139	458.0	COG1366@1|root,COG1922@1|root,COG1366@2|Bacteria,COG1922@2|Bacteria,2G6J0@200795|Chloroflexi,375GH@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase, WecB TagA CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB,STAS
GZD2_k127_4709622_3	765420.OSCT_0035	1.211e-79	274.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,374ZJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GZD2_k127_4709622_2	326427.Cagg_2079	5.908e-84	288.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsO	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
GZD2_k127_4714520_6	694427.Palpr_0130	1.645e-30	123.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,2FRUW@200643|Bacteroidia,22Y1X@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
GZD2_k127_4714520_1	926550.CLDAP_29050	3.256e-106	359.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
GZD2_k127_4714520_3	316274.Haur_3982	1.559e-47	181.0	COG1028@1|root,COG1028@2|Bacteria,2G9VV@200795|Chloroflexi,377FY@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_4714520_0	926550.CLDAP_29000	2.398e-136	447.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi	200795|Chloroflexi	L	DNA photolyase domain protein	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
GZD2_k127_4714520_5	373994.Riv7116_0606	3.207e-43	164.0	2B09D@1|root,31SK9@2|Bacteria	2|Bacteria	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
GZD2_k127_4714520_4	1227349.C170_13805	3.163e-46	172.0	COG0454@1|root,COG0456@2|Bacteria,1V9EJ@1239|Firmicutes,4HJGE@91061|Bacilli,26XNC@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_4714520_2	926550.CLDAP_20410	8.088e-49	182.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	cyp139A3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	-	-	-	-	-	-	-	-	-	p450
GZD2_k127_4726061_0	926569.ANT_14510	2.608e-97	323.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD2_k127_4726061_1	439235.Dalk_1565	1.716e-70	249.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GZD2_k127_4726061_4	1227349.C170_19805	2.587e-34	142.0	COG4330@1|root,COG4330@2|Bacteria,1VEKF@1239|Firmicutes,4HPYW@91061|Bacilli,26RZG@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
GZD2_k127_4726061_3	926550.CLDAP_05380	9.552e-41	156.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
GZD2_k127_4726061_5	497964.CfE428DRAFT_3478	2.125e-31	132.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
GZD2_k127_4726061_2	264732.Moth_2002	4.922e-65	233.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,42GF3@68295|Thermoanaerobacterales	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
GZD2_k127_4769220_5	28444.JODQ01000006_gene555	4.006e-10	72.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,Trans_reg_C,WD40
GZD2_k127_4769220_3	1265505.ATUG01000002_gene1171	1.485e-52	203.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
GZD2_k127_4769220_2	926569.ANT_27150	5.013e-166	539.0	COG0661@1|root,COG0661@2|Bacteria,2G6DN@200795|Chloroflexi	2|Bacteria	S	PFAM ABC-1 domain protein	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
GZD2_k127_4769220_4	573370.DMR_11920	2.801e-11	67.0	COG3937@1|root,COG3937@2|Bacteria,1NM7V@1224|Proteobacteria,42WSS@68525|delta/epsilon subdivisions,2WSW4@28221|Deltaproteobacteria,2MCKF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
GZD2_k127_4769220_6	1191523.MROS_1674	0.0005948	42.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GZD2_k127_4769220_1	449447.MAE_11610	5.949e-179	581.0	28JCI@1|root,2Z976@2|Bacteria,1G4JJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4769220_0	449447.MAE_11600	1.409e-181	586.0	2DB7G@1|root,2Z7M5@2|Bacteria,1G3PP@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_477713_1	234267.Acid_6905	2.602e-60	217.0	COG3336@1|root,COG3336@2|Bacteria,3Y6N7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GZD2_k127_477713_0	864069.MicloDRAFT_00060570	5.105e-106	355.0	28JN3@1|root,2Z9EI@2|Bacteria,1RHGC@1224|Proteobacteria,2U3IG@28211|Alphaproteobacteria,1JQZQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GZD2_k127_477713_4	1282360.ABAC460_07900	4.984e-14	74.0	COG3693@1|root,COG3693@2|Bacteria,1QWFB@1224|Proteobacteria,2TWY5@28211|Alphaproteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
GZD2_k127_477713_3	568768.CM001975_gene2552	3.208e-31	124.0	2DMJC@1|root,32RYJ@2|Bacteria,1RGW8@1224|Proteobacteria,1S6NK@1236|Gammaproteobacteria,2JE7Q@204037|Dickeya	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4186)	yneG	-	-	-	-	-	-	-	-	-	-	-	DUF4186
GZD2_k127_477713_2	63737.Npun_F0203	2.851e-41	155.0	COG1028@1|root,COG1028@2|Bacteria,1G264@1117|Cyanobacteria,1HJV4@1161|Nostocales	1117|Cyanobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_4802973_0	926569.ANT_16350	6.515e-237	740.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GZD2_k127_4802973_2	314260.PB2503_13244	3.645e-10	72.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
GZD2_k127_4802973_1	926550.CLDAP_02830	1.207e-58	206.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
GZD2_k127_4804461_3	399549.Msed_0919	2.362e-10	70.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Radical_SAM,SPASM
GZD2_k127_4804461_2	765420.OSCT_2914	8.66e-43	163.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GZD2_k127_4804461_0	765420.OSCT_2914	1.399e-76	267.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GZD2_k127_4804461_1	375451.RD1_2687	3.138e-44	170.0	COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GZD2_k127_4805767_4	1185876.BN8_06228	2.877e-18	88.0	2E4G6@1|root,32ZBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4805767_0	1185876.BN8_06227	4.686e-92	308.0	COG1018@1|root,COG1018@2|Bacteria,4PN6Y@976|Bacteroidetes,47TXC@768503|Cytophagia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523,ko:K05784	ko00362,ko00364,ko00520,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00520,map00622,map01100,map01120,map01220	M00551	R03391,R03392,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00230,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
GZD2_k127_4805767_1	1173020.Cha6605_1085	4.759e-85	286.0	COG2041@1|root,COG2041@2|Bacteria,1G22N@1117|Cyanobacteria	1117|Cyanobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GZD2_k127_4805767_6	118161.KB235922_gene3492	0.0001411	45.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,Peptidase_C14,WD40
GZD2_k127_4805767_2	479434.Sthe_0598	3.842e-84	312.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GZD2_k127_4805767_5	479432.Sros_7942	7.523e-12	79.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EFWB@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
GZD2_k127_4805767_3	523841.HFX_1666	3.71e-23	104.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GZD2_k127_4822164_1	1077972.ARGLB_039_00830	8.666e-49	179.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W8QW@1268|Micrococcaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GZD2_k127_4822164_0	926569.ANT_20820	3.692e-119	390.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GZD2_k127_4822164_3	926569.ANT_20810	5.33e-30	122.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
GZD2_k127_4822164_2	1047013.AQSP01000131_gene1797	5.527e-39	160.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_4822164_4	1391647.AVSV01000028_gene248	1.467e-16	84.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GZD2_k127_4822164_5	345341.KUTG_04140	1.932e-09	63.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4824015_0	926569.ANT_11970	2.834e-122	400.0	COG1148@1|root,COG1148@2|Bacteria,2G7GY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4824015_1	1499967.BAYZ01000083_gene1022	9.025e-82	284.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,CBAH
GZD2_k127_4826914_6	596330.HMPREF0628_0753	0.0008155	51.0	COG1716@1|root,COG1716@2|Bacteria,1VF0E@1239|Firmicutes,24PKU@186801|Clostridia,22H5Z@1570339|Peptoniphilaceae	186801|Clostridia	T	FHA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD2_k127_4826914_3	211165.AJLN01000050_gene5249	2.297e-07	63.0	COG1716@1|root,COG1716@2|Bacteria,1GBK0@1117|Cyanobacteria,1JHWR@1189|Stigonemataceae	1117|Cyanobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD2_k127_4826914_0	316274.Haur_2581	6.408e-291	946.0	COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi,376BF@32061|Chloroflexia	32061|Chloroflexia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
GZD2_k127_4826914_1	316274.Haur_2580	5.812e-60	220.0	COG0515@1|root,COG0515@2|Bacteria	316274.Haur_2580|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4826914_4	316274.Haur_4519	1.756e-06	53.0	COG1073@1|root,COG4842@1|root,COG1073@2|Bacteria,COG4842@2|Bacteria	2|Bacteria	S	protein secretion by the type VII secretion system	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	Abhydrolase_5,Peptidase_C2,WXG100
GZD2_k127_4835890_1	203119.Cthe_1845	1.422e-79	269.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,HTS
GZD2_k127_4835890_0	926550.CLDAP_17180	7.147e-232	722.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
GZD2_k127_4835890_2	926569.ANT_10760	8.154e-69	237.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GZD2_k127_4839374_2	926569.ANT_28330	3.144e-130	434.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GZD2_k127_4839374_5	65672.G4TN17	0.0005363	51.0	2EVD0@1|root,2SXD1@2759|Eukaryota,3AT6U@33154|Opisthokonta,3PGMB@4751|Fungi,3V6W8@5204|Basidiomycota,22AU1@155619|Agaricomycetes,3H7II@355688|Agaricomycetes incertae sedis	4751|Fungi	-	-	-	-	2.7.7.6	ko:K03006	ko00230,ko00240,ko01100,ko03020,ko05016,ko05168,ko05169,map00230,map00240,map01100,map03020,map05016,map05168,map05169	M00180	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	-
GZD2_k127_4839374_1	1123057.P872_04785	3.68e-157	511.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47K79@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
GZD2_k127_4839374_0	1121918.ARWE01000001_gene385	2.886e-164	529.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GZD2_k127_4839374_3	926569.ANT_22410	4.645e-25	109.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GZD2_k127_4839374_4	926569.ANT_22420	2.452e-12	69.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GZD2_k127_4880227_3	476272.RUMHYD_02343	1.517e-85	289.0	COG2070@1|root,COG2070@2|Bacteria,1VS86@1239|Firmicutes,25DQI@186801|Clostridia	186801|Clostridia	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4880227_0	469383.Cwoe_2232	3.063e-127	423.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4CRKM@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
GZD2_k127_4880227_2	246194.CHY_1258	5.014e-87	304.0	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,24AJF@186801|Clostridia,42G57@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM type III effector Hrp-dependent outers	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
GZD2_k127_4880227_1	1500301.JQMF01000008_gene1002	8.807e-127	413.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,4B889@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
GZD2_k127_4880227_4	1347368.HG964403_gene4120	4.247e-32	128.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,1ZIIG@1386|Bacillus	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_4908439_1	926569.ANT_15670	5.851e-64	243.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4908439_0	1347392.CCEZ01000049_gene1510	3.169e-101	342.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,36H8D@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GZD2_k127_4922002_0	926569.ANT_28730	6.691e-115	383.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_4922002_2	246194.CHY_1532	1.352e-15	87.0	COG0741@1|root,COG0741@2|Bacteria,1V5D1@1239|Firmicutes,24KM1@186801|Clostridia	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GZD2_k127_4924667_1	491915.Aflv_1238	6.273e-93	309.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,21V43@150247|Anoxybacillus	91061|Bacilli	E	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
GZD2_k127_4924667_0	926569.ANT_22270	3.207e-314	973.0	COG0153@1|root,COG1210@1|root,COG0153@2|Bacteria,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GZD2_k127_4924667_2	926569.ANT_21000	8.422e-43	159.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GZD2_k127_4924667_3	926550.CLDAP_35520	1.852e-27	117.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GZD2_k127_492656_4	926569.ANT_05360	3.467e-28	115.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GZD2_k127_492656_3	926569.ANT_25840	1.269e-97	327.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GZD2_k127_492656_1	926569.ANT_25850	3.116e-110	368.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_492656_2	926569.ANT_24710	2.088e-105	345.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GZD2_k127_492656_5	1460634.JCM19037_2800	4.121e-15	82.0	COG1595@1|root,COG1595@2|Bacteria,1V4T2@1239|Firmicutes,4HHRP@91061|Bacilli	91061|Bacilli	K	binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_492656_0	926569.ANT_25290	0.0	1251.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GZD2_k127_4931501_3	755732.Fluta_0376	2.361e-10	63.0	COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1IMHA@117743|Flavobacteriia,2PB3T@246874|Cryomorphaceae	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
GZD2_k127_4931501_1	316274.Haur_3626	1.884e-161	527.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_4931501_0	926569.ANT_20580	1.828e-181	573.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GZD2_k127_4931501_2	926569.ANT_20570	2.442e-35	135.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GZD2_k127_4931639_2	1405.DJ92_337	1.716e-41	160.0	COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,1ZCXY@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	gmT1	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_4931639_0	649638.Trad_1980	7.493e-79	276.0	COG1609@1|root,COG1609@2|Bacteria,1WMBZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_4931639_1	373903.Hore_13200	1.384e-65	242.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes	1239|Firmicutes	G	ABC transporter, substratebinding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
GZD2_k127_4931639_3	1231185.BAMP01000001_gene4272	0.0005146	47.0	COG1175@1|root,COG1175@2|Bacteria,1MXK1@1224|Proteobacteria,2TUVU@28211|Alphaproteobacteria,43HZB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane	aglF	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GZD2_k127_4939693_8	1499967.BAYZ01000019_gene6325	3.147e-41	163.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD2_k127_4939693_9	926569.ANT_00160	2.886e-37	147.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4939693_7	926550.CLDAP_06330	5.932e-48	176.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
GZD2_k127_4939693_5	316274.Haur_3390	2.326e-52	209.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2G8T7@200795|Chloroflexi,3780G@32061|Chloroflexia	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
GZD2_k127_4939693_6	358823.DF19_31775	1.757e-49	184.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_4939693_0	316274.Haur_0260	2.107e-183	593.0	COG0589@1|root,COG3842@1|root,COG0589@2|Bacteria,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,3758E@32061|Chloroflexia	2|Bacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
GZD2_k127_4939693_1	316274.Haur_0259	7.377e-143	461.0	COG1613@1|root,COG1613@2|Bacteria	2|Bacteria	P	Sulfate ABC transporter periplasmic sulfate-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
GZD2_k127_4939693_3	316274.Haur_0258	1.556e-96	325.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
GZD2_k127_4939693_4	316274.Haur_0257	7.498e-92	312.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
GZD2_k127_4939693_2	926569.ANT_25980	7.445e-118	392.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GZD2_k127_4950412_0	926569.ANT_20730	7.344e-227	719.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GZD2_k127_4950412_1	404380.Gbem_1628	4.467e-52	193.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_4956600_0	1408422.JHYF01000004_gene1723	7.108e-214	676.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,36FZW@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
GZD2_k127_4956600_3	1121272.KB903249_gene2255	8.839e-43	162.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GZD2_k127_4956600_5	1463920.JOGB01000019_gene2362	4.929e-06	52.0	COG0222@1|root,COG0222@2|Bacteria,2GQUV@201174|Actinobacteria	201174|Actinobacteria	J	Ribosomal protein L7/L12 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L12
GZD2_k127_4956600_1	203124.Tery_2689	4.074e-84	290.0	COG0810@1|root,COG1262@1|root,COG4249@1|root,COG0810@2|Bacteria,COG1262@2|Bacteria,COG4249@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H9P9@1150|Oscillatoriales	1117|Cyanobacteria	M	Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
GZD2_k127_4956600_6	1121904.ARBP01000001_gene5615	4.021e-05	52.0	2E7HQ@1|root,33207@2|Bacteria,4NYBI@976|Bacteroidetes,47UXQ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
GZD2_k127_4956600_4	350688.Clos_0560	8.777e-25	106.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia,36N4Z@31979|Clostridiaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD2_k127_4956600_2	926569.ANT_15600	8.313e-82	280.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GZD2_k127_4965540_1	383372.Rcas_3156	1.146e-97	329.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4965540_2	1521187.JPIM01000084_gene664	1.54e-67	258.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi,376D4@32061|Chloroflexia	32061|Chloroflexia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_8
GZD2_k127_4965540_4	926569.ANT_05350	1.424e-58	214.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GZD2_k127_4965540_5	1158338.JNLJ01000001_gene956	3.567e-56	205.0	COG0175@1|root,COG0175@2|Bacteria,2G4VI@200783|Aquificae	200783|Aquificae	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
GZD2_k127_4965540_0	926569.ANT_05360	4.261e-115	376.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
GZD2_k127_4967686_4	211165.AJLN01000037_gene1931	3.366e-12	69.0	COG0265@1|root,COG0265@2|Bacteria,1G3YY@1117|Cyanobacteria,1JIAQ@1189|Stigonemataceae	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_4967686_3	1128421.JAGA01000002_gene1677	8.52e-47	175.0	COG0265@1|root,COG0265@2|Bacteria,2NR4X@2323|unclassified Bacteria	2|Bacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_4967686_2	880073.Calab_3288	3.367e-52	198.0	2ES9V@1|root,33JUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4967686_1	338966.Ppro_1867	8.682e-53	192.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2X5QU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GZD2_k127_4967686_0	1382306.JNIM01000001_gene3678	6.628e-64	228.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
GZD2_k127_4971311_13	1499967.BAYZ01000193_gene3904	2.288e-15	78.0	2AR01@1|root,31G8U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4971311_3	1163407.UU7_08728	7.583e-104	344.0	COG0289@1|root,COG0289@2|Bacteria,1R4EU@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the DapB family	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
GZD2_k127_4971311_9	357808.RoseRS_0493	8.568e-33	137.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GZD2_k127_4971311_7	1198452.Jab_2c34270	1.543e-67	238.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4779T@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD2_k127_4971311_12	1122925.KB895384_gene3213	1.729e-16	88.0	COG1011@1|root,COG1011@2|Bacteria,1V3M1@1239|Firmicutes,4IUEQ@91061|Bacilli,26XHU@186822|Paenibacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GZD2_k127_4971311_8	243231.GSU2308	2.577e-57	206.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
GZD2_k127_4971311_6	224308.BSU23550	2.044e-72	250.0	COG0281@1|root,COG0281@2|Bacteria,1UYHB@1239|Firmicutes,4HDRG@91061|Bacilli,1ZDC7@1386|Bacillus	91061|Bacilli	C	malic enzyme	mleA	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C,ACT_4,Malic_M,THF_DHG_CYH_C,malic
GZD2_k127_4971311_0	926569.ANT_14860	1.937e-189	599.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
GZD2_k127_4971311_4	926550.CLDAP_35910	1.252e-94	319.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
GZD2_k127_4971311_1	765420.OSCT_1132	4.043e-127	413.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD2_k127_4971311_10	1121946.AUAX01000019_gene7793	3.579e-25	111.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria,4DEVY@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_4971311_11	936455.KI421499_gene374	7.451e-18	85.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,3JZF4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
GZD2_k127_4971311_5	926569.ANT_07470	3.877e-90	304.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GZD2_k127_4971311_2	926569.ANT_07480	7.404e-118	385.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
GZD2_k127_4973234_2	1002340.AFCF01000003_gene2826	3.749e-05	51.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TS7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0687 Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
GZD2_k127_4973234_0	926569.ANT_18190	3.281e-104	347.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
GZD2_k127_4973234_1	479434.Sthe_2201	5.867e-14	73.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD2_k127_4974112_1	306281.AJLK01000072_gene645	1.567e-42	160.0	COG1764@1|root,COG1764@2|Bacteria,1G767@1117|Cyanobacteria,1JKB8@1189|Stigonemataceae	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GZD2_k127_4974112_0	685778.AORL01000010_gene3085	7.172e-106	355.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,2UK7P@28211|Alphaproteobacteria,2K1N9@204457|Sphingomonadales	204457|Sphingomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
GZD2_k127_4974112_2	1122605.KB893646_gene219	4.387e-38	145.0	COG3461@1|root,COG3461@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
GZD2_k127_4974112_4	394.NGR_c30460	7.426e-05	52.0	COG4803@1|root,COG4803@2|Bacteria,1QU69@1224|Proteobacteria,2TW1D@28211|Alphaproteobacteria,4BNRW@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_4974112_3	1313172.YM304_06270	8.054e-38	151.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_4983676_1	926569.ANT_11800	3.054e-82	291.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_4983676_0	926569.ANT_11800	4.587e-115	406.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_4991056_2	326427.Cagg_2066	5.657e-68	240.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376FI@32061|Chloroflexia	32061|Chloroflexia	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
GZD2_k127_4991056_4	1173028.ANKO01000018_gene1166	1.225e-55	201.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GZD2_k127_4991056_1	324602.Caur_1636	2.595e-72	255.0	COG1216@1|root,COG1216@2|Bacteria,2G8VQ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_4991056_3	326427.Cagg_2074	1.22e-61	229.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K07011,ko:K07184	-	-	-	-	ko00000	-	-	-	Wzz
GZD2_k127_4991056_0	765420.OSCT_0005	4.237e-97	336.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
GZD2_k127_49925_1	1157490.EL26_03695	2.027e-47	183.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,27AQB@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GZD2_k127_49925_2	1229780.BN381_420033	9.389e-25	114.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Ferric_reduct,NAD_binding_1
GZD2_k127_49925_0	926569.ANT_15680	3.725e-70	245.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi	200795|Chloroflexi	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD2_k127_5004231_9	1173029.JH980292_gene614	0.0002928	52.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
GZD2_k127_5004231_3	1123274.KB899410_gene3452	1.165e-57	210.0	2C7XN@1|root,32RK1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD2_k127_5004231_5	479434.Sthe_2178	6.237e-45	172.0	2A522@1|root,30TQD@2|Bacteria,2G9FX@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5004231_6	351160.RCIX50	2.198e-33	139.0	COG1277@1|root,arCOG02436@2157|Archaea	2157|Archaea	S	ABC-type transport system involved in multi-copper enzyme maturation, permease	nosY2	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GZD2_k127_5004231_2	351160.RCIX51	8.995e-120	392.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_5004231_0	1121324.CLIT_10c01870	1.679e-162	527.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GZD2_k127_5004231_7	479434.Sthe_1930	1.228e-22	104.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5004231_1	304371.MCP_1300	1.839e-130	426.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GZD2_k127_5004231_4	304371.MCP_1301	1.075e-46	180.0	arCOG09180@1|root,arCOG09180@2157|Archaea,2XTAJ@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
GZD2_k127_5007653_3	643473.KB235930_gene2947	4.073e-28	116.0	2C4F3@1|root,32D38@2|Bacteria,1G6WA@1117|Cyanobacteria,1HS8W@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5007653_2	643473.KB235930_gene2946	1.117e-32	133.0	2CA6H@1|root,32RQP@2|Bacteria,1G86X@1117|Cyanobacteria,1HS6T@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD2_k127_5007653_4	316274.Haur_1286	1.957e-10	74.0	COG2453@1|root,COG2453@2|Bacteria,2G9BP@200795|Chloroflexi,377V3@32061|Chloroflexia	32061|Chloroflexia	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5007653_0	742765.HMPREF9457_03673	9.654e-211	679.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,27V45@189330|Dorea	186801|Clostridia	K	Likely ribonuclease with RNase H fold.	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GZD2_k127_5007653_1	861299.J421_0531	3.023e-117	392.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
GZD2_k127_500959_3	1121428.DESHY_160236___1	1.827e-21	96.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,261B5@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_500959_0	1499967.BAYZ01000065_gene6086	7.483e-168	534.0	COG3938@1|root,COG3938@2|Bacteria,2NQES@2323|unclassified Bacteria	2|Bacteria	E	Proline racemase	-	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
GZD2_k127_500959_2	1128421.JAGA01000002_gene796	6.495e-59	208.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GZD2_k127_500959_1	525904.Tter_0668	5.758e-63	220.0	COG2514@1|root,COG2514@2|Bacteria,2NRH9@2323|unclassified Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GZD2_k127_5011947_0	1123508.JH636452_gene7055	5.068e-92	308.0	COG1028@1|root,COG1028@2|Bacteria	1123508.JH636452_gene7055|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5011947_1	439235.Dalk_2729	8.956e-43	166.0	COG3809@1|root,COG3809@2|Bacteria,1PZB0@1224|Proteobacteria,433GD@68525|delta/epsilon subdivisions,2WXX5@28221|Deltaproteobacteria,2MP8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
GZD2_k127_5011947_2	485915.Dret_2352	3.517e-24	111.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
GZD2_k127_5011947_3	247490.KSU1_B0215	6.39e-15	75.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_5014644_1	926569.ANT_26640	4.039e-98	339.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GZD2_k127_5014644_0	926569.ANT_26640	9.477e-101	349.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
GZD2_k127_5014644_3	1121127.JAFA01000010_gene3933	5.872e-07	55.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2VKXI@28216|Betaproteobacteria,1K6J0@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GZD2_k127_5014644_5	1144305.PMI02_04445	3.14e-05	48.0	COG2124@1|root,COG2124@2|Bacteria,1R599@1224|Proteobacteria,2U0QG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	cytochrome P-450	CYP112A	-	-	ko:K21116	-	-	-	-	ko00000,ko00199	-	-	-	p450
GZD2_k127_5014644_2	208439.AJAP_32550	2.827e-32	148.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria,4ECXP@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
GZD2_k127_5014644_4	1144312.PMI09_04722	2.105e-05	59.0	COG1749@1|root,COG1749@2|Bacteria,1QXET@1224|Proteobacteria,2TX9Q@28211|Alphaproteobacteria,4B7MV@82115|Rhizobiaceae	28211|Alphaproteobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
GZD2_k127_5020439_0	880073.Calab_0341	1.155e-253	789.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GZD2_k127_5043720_2	880073.Calab_1089	1.399e-35	143.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoCD	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
GZD2_k127_5043720_0	472759.Nhal_2141	6.698e-103	338.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GZD2_k127_5043720_1	323848.Nmul_A1013	7.682e-43	159.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2W894@28216|Betaproteobacteria,3748A@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GZD2_k127_5043720_5	1541065.JRFE01000057_gene6269	5.125e-23	102.0	2DUIA@1|root,32UXB@2|Bacteria	2|Bacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
GZD2_k127_5043720_4	335543.Sfum_2936	1.015e-25	111.0	COG0346@1|root,COG0346@2|Bacteria,1N57W@1224|Proteobacteria	1224|Proteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
GZD2_k127_5043720_3	641491.DND132_1003	4.078e-35	135.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2X6YF@28221|Deltaproteobacteria,2M8DU@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Fumarate lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
GZD2_k127_5052084_2	926550.CLDAP_20410	2.177e-94	319.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	cyp139A3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	-	-	-	-	-	-	-	-	-	p450
GZD2_k127_5052084_3	937777.Deipe_2605	7.187e-39	157.0	COG2324@1|root,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
GZD2_k127_5052084_1	1321778.HMPREF1982_02748	2.215e-116	390.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,2686Y@186813|unclassified Clostridiales	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
GZD2_k127_5052084_0	926569.ANT_04660	6.929e-149	474.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GZD2_k127_5053321_1	1312954.KI914846_gene1736	1.71e-46	181.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
GZD2_k127_5053321_0	383372.Rcas_1300	5.171e-232	752.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
GZD2_k127_5058904_0	926550.CLDAP_18930	2.253e-177	565.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GZD2_k127_5058904_1	40384.G7X7W4	9.263e-06	48.0	COG3325@1|root,KOG2806@2759|Eukaryota,38BJK@33154|Opisthokonta,3NW3A@4751|Fungi,3QKIS@4890|Ascomycota,20CJ6@147545|Eurotiomycetes	4751|Fungi	G	Belongs to the glycosyl hydrolase 18 family	CHT4	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008061,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0030154,GO:0030435,GO:0032502,GO:0042737,GO:0043170,GO:0043934,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046348,GO:0048646,GO:0048856,GO:0048869,GO:0071704,GO:0097367,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,LysM
GZD2_k127_5063464_3	1121422.AUMW01000006_gene704	5.436e-47	172.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,26029@186807|Peptococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
GZD2_k127_5063464_4	926550.CLDAP_37590	5.326e-44	164.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	asnC	-	-	ko:K03718,ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
GZD2_k127_5063464_0	926550.CLDAP_37560	1.481e-137	454.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
GZD2_k127_5063464_1	926550.CLDAP_37550	1.762e-110	364.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi	200795|Chloroflexi	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GZD2_k127_5063464_2	926550.CLDAP_37540	6.378e-102	336.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
GZD2_k127_5064086_5	926560.KE387023_gene2407	1.305e-34	138.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GZD2_k127_5064086_7	1122927.KB895413_gene1466	0.0002596	52.0	COG1396@1|root,COG1396@2|Bacteria,1TSJ6@1239|Firmicutes,4HC63@91061|Bacilli,26T0H@186822|Paenibacillaceae	91061|Bacilli	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
GZD2_k127_5064086_3	106582.XP_004566527.1	4.872e-50	183.0	COG1437@1|root,KOG2589@2759|Eukaryota,3A4QC@33154|Opisthokonta,3BRFI@33208|Metazoa,3D8WI@33213|Bilateria,48EHS@7711|Chordata,49BAX@7742|Vertebrata,4A3UR@7898|Actinopterygii	33208|Metazoa	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
GZD2_k127_5064086_1	926569.ANT_03840	1.205e-53	194.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GZD2_k127_5064086_2	926569.ANT_03850	5.741e-53	209.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
GZD2_k127_5064086_0	926569.ANT_03860	8.706e-202	636.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
GZD2_k127_5064086_4	926569.ANT_03880	1.426e-36	144.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
GZD2_k127_5064086_6	926569.ANT_03890	4.752e-32	130.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5071478_3	926569.ANT_06210	1.109e-165	536.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
GZD2_k127_5071478_8	926569.ANT_03710	1.174e-37	148.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
GZD2_k127_5071478_1	670487.Ocepr_1935	3.239e-250	797.0	COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5071478_10	326427.Cagg_3758	4.118e-16	91.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5071478_9	326427.Cagg_3759	2.264e-37	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_5071478_7	926569.ANT_13320	4.085e-78	267.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
GZD2_k127_5071478_4	926569.ANT_13330	2.935e-143	461.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD2_k127_5071478_0	926569.ANT_13340	3.979e-256	820.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GZD2_k127_5071478_6	926569.ANT_13360	6.757e-80	273.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GZD2_k127_5071478_2	926569.ANT_13370	1.554e-215	677.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GZD2_k127_5071478_5	926569.ANT_13130	1.309e-101	334.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_5072136_5	926569.ANT_04790	9.986e-25	113.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.104	ko:K07273,ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_25,LysM
GZD2_k127_5072136_3	926569.ANT_04780	3.408e-42	161.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
GZD2_k127_5072136_2	316274.Haur_0169	3.296e-46	170.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	yffH	-	-	-	-	-	-	-	-	-	-	-	DUF4406
GZD2_k127_5072136_0	926569.ANT_28320	0.0	1779.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
GZD2_k127_5072136_1	926569.ANT_28310	1.191e-129	421.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GZD2_k127_5072136_4	926569.ANT_28280	7.16e-35	134.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GZD2_k127_5072136_6	926569.ANT_28270	1.155e-20	92.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GZD2_k127_507338_5	309798.COPRO5265_1458	7.396e-15	86.0	2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_507338_3	373903.Hore_21920	8.729e-64	230.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WA8W@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM hydrolase, TatD family	yabD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
GZD2_k127_507338_1	926569.ANT_14700	2.586e-108	359.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GZD2_k127_507338_4	926569.ANT_04110	7.789e-40	153.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GZD2_k127_507338_0	926569.ANT_04080	3.283e-284	883.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
GZD2_k127_507338_2	158190.SpiGrapes_0176	1.816e-66	239.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	rsbP	-	3.1.3.3	ko:K02660,ko:K07315,ko:K17763	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS,SpoIIE
GZD2_k127_5074251_1	375451.RD1_2687	1.267e-22	100.0	COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
GZD2_k127_5074251_0	378806.STAUR_7185	1.229e-55	209.0	COG1073@1|root,COG1073@2|Bacteria,1QX68@1224|Proteobacteria,43BYU@68525|delta/epsilon subdivisions,2X79P@28221|Deltaproteobacteria,2YW41@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5074251_2	1307436.PBF_13729	4.311e-15	85.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
GZD2_k127_5077667_3	398512.JQKC01000032_gene4454	1.244e-36	142.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,3WIWY@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
GZD2_k127_5077667_2	926569.ANT_29070	9.97e-38	147.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GZD2_k127_5077667_0	479434.Sthe_2134	2.673e-110	372.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
GZD2_k127_5077667_1	926550.CLDAP_19450	2.246e-77	266.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_5077667_5	526227.Mesil_2630	6.304e-24	105.0	COG0607@1|root,COG0607@2|Bacteria,1WMYS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GZD2_k127_5077667_4	861299.J421_4449	7.001e-26	111.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD2_k127_5080260_3	316274.Haur_3798	1.246e-85	294.0	COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi,3758A@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GZD2_k127_5080260_1	926560.KE387023_gene3378	6.378e-155	496.0	COG2267@1|root,COG2267@2|Bacteria,1WMAU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_5080260_0	926550.CLDAP_25140	3.234e-199	632.0	COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GZD2_k127_5080260_5	694427.Palpr_2982	0.0001134	46.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,2FTX8@200643|Bacteroidia,22YNU@171551|Porphyromonadaceae	976|Bacteroidetes	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_5080260_4	292563.Cyast_0296	1.616e-15	78.0	COG0399@1|root,COG0399@2|Bacteria,1G88E@1117|Cyanobacteria	1117|Cyanobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_5080260_2	926550.CLDAP_25150	1.338e-92	309.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD2_k127_5087137_4	926569.ANT_03500	1.495e-57	202.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GZD2_k127_5087137_2	926569.ANT_03510	4.796e-79	267.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GZD2_k127_5087137_1	926569.ANT_31010	9.832e-101	334.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GZD2_k127_5087137_3	926569.ANT_31020	6.568e-79	268.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GZD2_k127_5087137_0	926569.ANT_31030	3.731e-119	390.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GZD2_k127_5087368_0	926569.ANT_14340	9.896e-134	445.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
GZD2_k127_5087368_4	926569.ANT_14350	1.967e-36	143.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi	200795|Chloroflexi	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GZD2_k127_5087368_1	1185876.BN8_03087	1.187e-102	344.0	COG2201@1|root,COG2201@2|Bacteria,4NJF9@976|Bacteroidetes,47NTP@768503|Cytophagia	976|Bacteroidetes	NT	PFAM CheB methylesterase	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
GZD2_k127_5087368_2	485913.Krac_10797	4.509e-58	205.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269,HIT
GZD2_k127_5087368_3	118163.Ple7327_1229	2.685e-44	166.0	COG1280@1|root,COG1280@2|Bacteria,1G8NE@1117|Cyanobacteria,3VKUI@52604|Pleurocapsales	1117|Cyanobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GZD2_k127_5089037_0	926569.ANT_13040	0.0	1052.0	COG1391@1|root,COG2844@1|root,COG1391@2|Bacteria,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89	ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020	M00017,M00018	R00243,R01773,R01775	RC00006,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	GlnD_UR_UTase,GlnE,HD
GZD2_k127_5089037_2	926569.ANT_13030	4.591e-242	754.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GZD2_k127_5089037_8	1382356.JQMP01000003_gene1402	1.056e-42	164.0	COG1280@1|root,COG1280@2|Bacteria,2GBTW@200795|Chloroflexi,27ZC9@189775|Thermomicrobia	189775|Thermomicrobia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GZD2_k127_5089037_3	926569.ANT_16280	3.605e-206	664.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA_2
GZD2_k127_5089037_6	926569.ANT_16270	1.249e-86	301.0	COG2197@1|root,COG2204@1|root,COG2197@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	yhjB	GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_5089037_1	925409.KI911562_gene1594	3.19e-254	797.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IVNE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Glyco_hydro_3,Glyco_hydro_3_C,fn3
GZD2_k127_5089037_9	697281.Mahau_2859	1.558e-10	63.0	COG0407@1|root,COG0407@2|Bacteria	697281.Mahau_2859|-	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5089037_4	388401.RB2150_09259	8.215e-104	345.0	COG2801@1|root,COG2801@2|Bacteria,1RG0C@1224|Proteobacteria,2U7S5@28211|Alphaproteobacteria,3ZHKU@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve,rve_3
GZD2_k127_5089037_5	1128421.JAGA01000001_gene2050	8.763e-89	297.0	COG3822@1|root,COG3822@2|Bacteria,2NQJ1@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF1498	Z012_00995	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
GZD2_k127_5089037_7	926550.CLDAP_03280	1.786e-55	196.0	COG1957@1|root,COG1957@2|Bacteria,2G7IF@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
GZD2_k127_5099998_0	1382306.JNIM01000001_gene2428	2.774e-173	547.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD2_k127_5099998_1	485913.Krac_9360	1.401e-146	471.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
GZD2_k127_5099998_4	485913.Krac_9361	4.98e-117	385.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GZD2_k127_5099998_8	485913.Krac_9362	9.285e-67	234.0	COG2186@1|root,COG2186@2|Bacteria,2G959@200795|Chloroflexi	200795|Chloroflexi	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD2_k127_5099998_3	324602.Caur_0890	5.168e-127	416.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1
GZD2_k127_5099998_2	765420.OSCT_0028	1.024e-137	447.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_5099998_7	1144275.COCOR_08057	3.338e-93	328.0	COG3534@1|root,COG3534@2|Bacteria,1RE68@1224|Proteobacteria,43C04@68525|delta/epsilon subdivisions,2X7AW@28221|Deltaproteobacteria,2YZ4E@29|Myxococcales	28221|Deltaproteobacteria	G	Glycoside hydrolase family 44	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44
GZD2_k127_5099998_5	324602.Caur_1643	2.75e-99	336.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD2_k127_5099998_10	324602.Caur_1642	9.847e-63	220.0	COG1045@1|root,COG1045@2|Bacteria	2|Bacteria	E	serine acetyltransferase	wcaB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iECW_1372.ECW_m2215,iWFL_1372.ECW_m2215	Hexapep,Hexapep_2
GZD2_k127_5099998_6	326427.Cagg_2374	6.831e-98	330.0	COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_5099998_9	324602.Caur_1640	7.94e-66	229.0	COG0110@1|root,COG0110@2|Bacteria,2G9TX@200795|Chloroflexi	200795|Chloroflexi	H	Transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5099998_11	765420.OSCT_0060	1.259e-42	162.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi,376J8@32061|Chloroflexia	32061|Chloroflexia	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
GZD2_k127_5099998_13	765420.OSCT_0003	2.358e-17	84.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD2_k127_5113040_2	311424.DhcVS_1083	2.438e-51	186.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD2_k127_5113040_0	926569.ANT_11910	3.596e-62	222.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD2_k127_5113040_1	1206731.BAGB01000049_gene4889	1.833e-58	220.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7
GZD2_k127_5113040_3	313589.JNB_17843	7.143e-43	162.0	2EMAT@1|root,33EZU@2|Bacteria,2HMP6@201174|Actinobacteria,4FHFN@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5113040_4	204669.Acid345_3113	7.165e-10	60.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GZD2_k127_5122346_1	926569.ANT_07180	7.312e-98	329.0	COG4819@1|root,COG4819@2|Bacteria	2|Bacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GZD2_k127_5122346_2	1476583.DEIPH_ctg050orf0040	2.773e-49	179.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC,TusA
GZD2_k127_5122346_0	926569.ANT_07190	1.417e-237	742.0	COG4303@1|root,COG4303@2|Bacteria,2G7NW@200795|Chloroflexi	200795|Chloroflexi	E	Ethanolamine ammonia lyase large subunit (EutB)	-	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
GZD2_k127_5136694_3	794846.AJQU01000003_gene1155	1.501e-31	124.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,2VG3M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
GZD2_k127_5136694_0	509191.AEDB02000081_gene2454	4.688e-51	187.0	COG4894@1|root,COG4894@2|Bacteria,1VUCV@1239|Firmicutes,250FU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5136694_1	926569.ANT_30300	1.247e-48	181.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5136694_2	926569.ANT_22760	1.672e-45	168.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	MFS_1
GZD2_k127_51420_0	926569.ANT_27130	1.115e-82	281.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GZD2_k127_51420_1	926569.ANT_29850	8.698e-34	141.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5144593_3	926569.ANT_11040	7.491e-62	219.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GZD2_k127_5144593_2	926569.ANT_20830	2.392e-108	362.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
GZD2_k127_5144593_4	604331.AUHY01000042_gene2025	7.722e-33	135.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GZD2_k127_5144593_1	926569.ANT_29590	1.526e-113	375.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GZD2_k127_5144593_0	1312959.KI914645_gene983	5.301e-128	424.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W8QW@1268|Micrococcaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GZD2_k127_5152207_4	926569.ANT_25680	9.507e-97	327.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD2_k127_5152207_2	926569.ANT_25670	1.59e-139	462.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
GZD2_k127_5152207_0	926569.ANT_30160	1.878e-199	627.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_5152207_5	1499967.BAYZ01000008_gene5408	7.488e-54	204.0	COG2931@1|root,COG2931@2|Bacteria,2NQ7A@2323|unclassified Bacteria	2|Bacteria	Q	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Calx-beta,DUF4214,DUF4347,Peptidase_C11,SLH,SWM_repeat
GZD2_k127_5152207_3	292415.Tbd_1114	3.253e-109	362.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GZD2_k127_5152207_1	926569.ANT_11040	6.161e-173	550.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
GZD2_k127_5159248_11	1117315.AHCA01000016_gene1611	5.9e-23	105.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,2Q3TN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_5159248_2	1094980.Mpsy_3062	1.642e-96	326.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,2NAUF@224756|Methanomicrobia	224756|Methanomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_5159248_4	926569.ANT_25730	5.005e-66	244.0	COG0596@1|root,COG1073@1|root,COG1266@1|root,COG0596@2|Bacteria,COG1073@2|Bacteria,COG1266@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GZD2_k127_5159248_10	521011.Mpal_1797	4.528e-32	132.0	COG2020@1|root,arCOG03580@2157|Archaea,2XXQD@28890|Euryarchaeota	28890|Euryarchaeota	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GZD2_k127_5159248_8	1121380.JNIW01000019_gene3488	6.735e-40	156.0	COG0393@1|root,COG0393@2|Bacteria,1WK5V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
GZD2_k127_5159248_0	935948.KE386494_gene437	4.789e-130	423.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,25B3Z@186801|Clostridia,42G02@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_5159248_9	1280692.AUJL01000001_gene167	9.978e-40	153.0	2C5N5@1|root,32Y15@2|Bacteria,1VEIC@1239|Firmicutes,24I2X@186801|Clostridia,36VBS@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5159248_13	521674.Plim_2985	0.0009538	45.0	COG1002@1|root,COG1002@2|Bacteria,2J0CD@203682|Planctomycetes	203682|Planctomycetes	L	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5159248_12	592029.DDD_3120	1.123e-08	68.0	COG2815@1|root,COG2815@2|Bacteria,4NXFG@976|Bacteroidetes,1I6HM@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	TIR_2
GZD2_k127_5159248_7	1457250.BBMO01000001_gene298	6.734e-47	188.0	COG1208@1|root,arCOG00666@2157|Archaea,2XUA6@28890|Euryarchaeota,23SNR@183963|Halobacteria	183963|Halobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	graD	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GZD2_k127_5159248_3	316274.Haur_3830	2.747e-79	273.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_5159248_5	543728.Vapar_1004	1.213e-55	196.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,2W2HP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
GZD2_k127_5159248_1	485913.Krac_7710	1.832e-100	330.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD2_k127_5159248_6	1121091.AUMP01000023_gene3823	1.312e-47	178.0	COG3382@1|root,COG3382@2|Bacteria,1TT38@1239|Firmicutes,4HCE2@91061|Bacilli	91061|Bacilli	K	B3 4 domain protein	XK27_07210	-	-	-	-	-	-	-	-	-	-	-	B3_4
GZD2_k127_5160129_2	926569.ANT_10310	1.444e-144	462.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GZD2_k127_5160129_7	926569.ANT_10320	1.109e-49	179.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GZD2_k127_5160129_5	926569.ANT_10330	3.482e-68	240.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GZD2_k127_5160129_6	926569.ANT_10340	8.666e-52	186.0	COG0102@1|root,COG0102@2|Bacteria,2G6M4@200795|Chloroflexi	200795|Chloroflexi	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GZD2_k127_5160129_9	926569.ANT_10350	2.191e-45	167.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GZD2_k127_5160129_3	926569.ANT_10380	2.021e-101	341.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
GZD2_k127_5160129_11	316274.Haur_1185	1.454e-33	141.0	COG0454@1|root,COG0456@2|Bacteria,2G9MN@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_5160129_16	1128421.JAGA01000002_gene64	1.366e-11	74.0	2DRD4@1|root,33B9X@2|Bacteria,2NRTN@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5160129_1	189753.AXAS01000017_gene3061	2.204e-164	531.0	COG1622@1|root,COG2132@1|root,COG3474@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,COG3474@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,3JV1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
GZD2_k127_5160129_19	1231190.NA8A_19263	1.739e-05	51.0	2EKB5@1|root,33E1I@2|Bacteria,1N7R4@1224|Proteobacteria,2UFB0@28211|Alphaproteobacteria,43MEF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
GZD2_k127_5160129_8	639283.Snov_1148	3.701e-49	183.0	COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,3F0E9@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnrR	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD2_k127_5160129_12	926569.ANT_12610	1.144e-32	129.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GZD2_k127_5160129_15	926569.ANT_12600	1.759e-18	87.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
GZD2_k127_5160129_0	926569.ANT_12590	0.0	1099.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GZD2_k127_5160129_10	926550.CLDAP_14450	2.667e-40	158.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GZD2_k127_5160129_13	867903.ThesuDRAFT_01405	4.482e-26	113.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
GZD2_k127_5160129_14	653733.Selin_0567	8.699e-24	106.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
GZD2_k127_5160129_4	118005.AWNK01000010_gene335	3.174e-99	339.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
GZD2_k127_5160129_17	118005.AWNK01000010_gene334	1.383e-11	76.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,HMA
GZD2_k127_5160129_18	926550.CLDAP_38270	3.634e-07	62.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GZD2_k127_5168462_0	926569.ANT_04530	2.874e-172	547.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
GZD2_k127_5168462_1	326427.Cagg_2505	1.355e-79	269.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,375KD@32061|Chloroflexia	32061|Chloroflexia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GZD2_k127_5168462_3	652103.Rpdx1_0626	7.223e-07	61.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria,2TT0Y@28211|Alphaproteobacteria,3JU1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GZD2_k127_5168462_2	247490.KSU1_C1426	1.896e-41	158.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
GZD2_k127_5172779_4	1347087.CBYO010000014_gene2236	1.297e-06	52.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
GZD2_k127_5172779_3	1192034.CAP_8495	5.429e-61	221.0	COG4632@1|root,COG4632@2|Bacteria,1PIAX@1224|Proteobacteria,43DRZ@68525|delta/epsilon subdivisions,2WYR4@28221|Deltaproteobacteria,2Z0EH@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
GZD2_k127_5172779_1	926569.ANT_14370	1.185e-112	371.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
GZD2_k127_5172779_0	926569.ANT_14380	1.198e-158	512.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_5172779_2	926569.ANT_11300	1.779e-107	357.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_519669_0	383372.Rcas_0907	1.221e-83	286.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi,376DF@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_519669_2	1007103.AFHW01000067_gene4083	1.506e-30	138.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HG03@91061|Bacilli,274I0@186822|Paenibacillaceae	91061|Bacilli	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GZD2_k127_519669_5	1303518.CCALI_01744	1.071e-09	71.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GZD2_k127_519669_6	1158612.I580_02564	1.809e-05	57.0	COG1349@1|root,COG1349@2|Bacteria,1VRTM@1239|Firmicutes,4HUHP@91061|Bacilli,4B1DG@81852|Enterococcaceae	91061|Bacilli	K	DeoR C terminal sensor domain	-	-	-	ko:K02530	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GZD2_k127_519669_1	1501230.ET33_01655	9.664e-76	278.0	COG1879@1|root,COG1879@2|Bacteria,1U358@1239|Firmicutes,4ICWB@91061|Bacilli,272UR@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_519669_4	526225.Gobs_2644	3.41e-17	96.0	COG1879@1|root,COG1879@2|Bacteria,2HEHI@201174|Actinobacteria,4EU2V@85013|Frankiales	201174|Actinobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	frcB	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
GZD2_k127_519669_3	411902.CLOBOL_02423	9.597e-21	92.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,221S1@1506553|Lachnoclostridium	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
GZD2_k127_5203819_1	272559.BF9343_1155	3.574e-154	496.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,2FMVE@200643|Bacteroidia,4AM7I@815|Bacteroidaceae	976|Bacteroidetes	E	COG1760 L-serine deaminase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
GZD2_k127_5203819_0	1173026.Glo7428_2548	6.214e-178	580.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9
GZD2_k127_5205390_8	926569.ANT_23750	9.89e-19	89.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
GZD2_k127_5205390_0	926569.ANT_23760	4.488e-140	451.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
GZD2_k127_5205390_6	1312954.KI914846_gene1736	3.176e-45	178.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
GZD2_k127_5205390_7	926569.ANT_19500	2.154e-44	167.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	rfaH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
GZD2_k127_5205390_1	489825.LYNGBM3L_38070	8.298e-100	335.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria,1HI6Y@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
GZD2_k127_5205390_9	1340493.JNIF01000003_gene1961	6.956e-05	54.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
GZD2_k127_5205390_5	67352.JODS01000004_gene6046	5.461e-64	233.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
GZD2_k127_5205390_4	28072.Nos7524_0341	2.836e-64	233.0	COG1215@1|root,COG1215@2|Bacteria,1G3C9@1117|Cyanobacteria,1HTUP@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_5205390_3	794846.AJQU01000039_gene4936	1.248e-68	247.0	COG4424@1|root,COG4424@2|Bacteria,1N2S4@1224|Proteobacteria,2UIR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GZD2_k127_5205390_2	649638.Trad_2723	7.722e-71	246.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
GZD2_k127_5206990_1	1122223.KB890687_gene2749	1.308e-115	387.0	COG3345@1|root,COG3345@2|Bacteria,1WIV5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
GZD2_k127_5206990_0	926569.ANT_22850	0.0	1307.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GZD2_k127_5228061_1	357808.RoseRS_1085	2.421e-106	348.0	COG1082@1|root,COG1082@2|Bacteria,2G6W6@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
GZD2_k127_5228061_2	357808.RoseRS_2512	7.941e-103	344.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,375NG@32061|Chloroflexia	32061|Chloroflexia	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_5228061_3	525904.Tter_0164	7.355e-99	331.0	COG1940@1|root,COG1940@2|Bacteria,2NQJS@2323|unclassified Bacteria	2|Bacteria	GK	ROK family	scrK	-	2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_5228061_4	411902.CLOBOL_02422	2.725e-85	293.0	COG1172@1|root,COG1172@2|Bacteria,1VT3C@1239|Firmicutes,24XN0@186801|Clostridia	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
GZD2_k127_5228061_0	411902.CLOBOL_02423	1.731e-210	664.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,221S1@1506553|Lachnoclostridium	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
GZD2_k127_5228061_5	1501230.ET33_01655	4.576e-75	262.0	COG1879@1|root,COG1879@2|Bacteria,1U358@1239|Firmicutes,4ICWB@91061|Bacilli,272UR@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_522927_0	926550.CLDAP_20840	1.763e-111	364.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GZD2_k127_522927_2	926569.ANT_26900	6.308e-24	117.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X
GZD2_k127_522927_1	383372.Rcas_1915	1.625e-36	144.0	COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia	32061|Chloroflexia	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_5251890_1	941639.BCO26_1524	2.288e-61	214.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus	91061|Bacilli	J	asparaginyl-tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GZD2_k127_5251890_4	1094508.Tsac_1055	2.097e-08	66.0	COG1388@1|root,COG1388@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia,42FCR@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
GZD2_k127_5251890_3	313612.L8106_10357	1.156e-36	152.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1G3TT@1117|Cyanobacteria,1H8M4@1150|Oscillatoriales	1117|Cyanobacteria	M	SMART Glycoside hydrolase, family 25 subgroup	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
GZD2_k127_5251890_2	457396.CSBG_03362	1.064e-47	184.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
GZD2_k127_5251890_0	357808.RoseRS_2594	1.267e-79	266.0	COG1231@1|root,COG1231@2|Bacteria,2G942@200795|Chloroflexi	200795|Chloroflexi	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GZD2_k127_5260459_8	926569.ANT_14220	5.438e-20	91.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_14220|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5260459_3	926569.ANT_14190	7.404e-61	218.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD2_k127_5260459_5	1131269.AQVV01000047_gene2079	9.906e-45	168.0	COG1111@1|root,COG1111@2|Bacteria	2|Bacteria	L	helicase activity	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HA,Helicase_C,Mrr_cat_2,ResIII
GZD2_k127_5260459_0	926569.ANT_14180	3.814e-121	408.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
GZD2_k127_5260459_2	926569.ANT_14170	4.262e-74	253.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GZD2_k127_5260459_1	926569.ANT_14160	1.306e-87	293.0	COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi	200795|Chloroflexi	F	PFAM thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
GZD2_k127_5260459_4	926569.ANT_25140	3.179e-53	192.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
GZD2_k127_5260459_7	926569.ANT_25130	2.081e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GZD2_k127_5260459_6	641143.HMPREF9331_01483	1.593e-36	146.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,1EQPR@1016|Capnocytophaga	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
GZD2_k127_5270224_5	926569.ANT_22990	3.845e-57	205.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like,SusD-like_2
GZD2_k127_5270224_4	1408418.JNJH01000050_gene202	1.003e-87	299.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2JPYH@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GZD2_k127_5270224_1	926569.ANT_30620	8.754e-170	539.0	COG1932@1|root,COG1932@2|Bacteria,2G7RM@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
GZD2_k127_5270224_2	926569.ANT_23020	4.889e-144	478.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_5270224_3	926569.ANT_23030	5.893e-101	342.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
GZD2_k127_5270224_0	926569.ANT_01520	1.028e-182	576.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
GZD2_k127_528567_3	1240350.AMZE01000011_gene3740	2.604e-48	183.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
GZD2_k127_528567_4	1221522.B723_12355	3.204e-26	121.0	COG5338@1|root,COG5338@2|Bacteria,1N67Y@1224|Proteobacteria,1SC1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_528567_2	1215114.BBIU01000002_gene252	1.059e-53	194.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
GZD2_k127_528567_0	395494.Galf_1165	5.523e-200	627.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VNAZ@28216|Betaproteobacteria,44W6M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
GZD2_k127_528567_1	395494.Galf_1292	2.151e-181	581.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2W9JS@28216|Betaproteobacteria,44W6R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial sugar transferase	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
GZD2_k127_5287411_1	99598.Cal7507_0048	1.324e-58	219.0	COG2199@1|root,COG3706@2|Bacteria,1G3FB@1117|Cyanobacteria,1HM2U@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA_7TM,PAS_4,PAS_8
GZD2_k127_5287411_3	1143323.M787_0036	5.299e-09	62.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD2_k127_5287411_2	926569.ANT_31290	3.198e-09	69.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
GZD2_k127_5287411_0	398512.JQKC01000023_gene3311	2.218e-99	328.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia,3WN6R@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
GZD2_k127_5301082_0	926569.ANT_28150	7.872e-128	426.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GZD2_k127_5301082_1	1120985.AUMI01000016_gene1921	2.278e-05	48.0	COG1149@1|root,COG1149@2|Bacteria,1VUEG@1239|Firmicutes,4H522@909932|Negativicutes	909932|Negativicutes	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5329898_4	517418.Ctha_0130	3.078e-102	347.0	COG0247@1|root,COG0247@2|Bacteria,1FDTD@1090|Chlorobi	1090|Chlorobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
GZD2_k127_5329898_5	517418.Ctha_0131	5.427e-91	308.0	COG2025@1|root,COG2025@2|Bacteria,1FE6B@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
GZD2_k127_5329898_8	562970.Btus_2493	1.028e-55	203.0	COG2086@1|root,COG2086@2|Bacteria,1VUFC@1239|Firmicutes	1239|Firmicutes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
GZD2_k127_5329898_1	309801.trd_0150	3.542e-191	604.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
GZD2_k127_5329898_9	309801.trd_0151	2.212e-55	203.0	2DPCA@1|root,331H2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5329898_2	309801.trd_0153	2.179e-160	511.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
GZD2_k127_5329898_0	309801.trd_0154	3.79e-222	693.0	COG2048@1|root,COG2048@2|Bacteria	2|Bacteria	C	Heterodisulfide reductase, subunit B	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
GZD2_k127_5329898_3	309801.trd_0155	9.413e-119	385.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	dld	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
GZD2_k127_5329898_10	309801.trd_0158	1.932e-51	184.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
GZD2_k127_5329898_12	926569.ANT_27430	6.101e-14	76.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD2_k127_5329898_6	309801.trd_0159	1.293e-70	243.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
GZD2_k127_5329898_11	309801.trd_0160	3.708e-31	125.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
GZD2_k127_5329898_7	926550.CLDAP_30530	1.754e-59	226.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_3,HATPase_c,HisKA_3
GZD2_k127_5338282_2	1297742.A176_07290	2.888e-48	175.0	COG0332@1|root,COG0332@2|Bacteria,1NSH9@1224|Proteobacteria,42Z79@68525|delta/epsilon subdivisions,2WUD8@28221|Deltaproteobacteria,2YUSN@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD2_k127_5338282_3	1521187.JPIM01000014_gene1786	2e-39	155.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_5338282_1	1287276.X752_22220	1.283e-83	290.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRS5@28211|Alphaproteobacteria,43KWE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
GZD2_k127_5338282_0	35754.JNYJ01000075_gene8647	3.943e-173	552.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1,Cyt_c_ox_IV
GZD2_k127_535331_2	324602.Caur_1106	6.269e-112	373.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	srrA1	-	-	ko:K02027,ko:K17244	ko02010,map02010	M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.40	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_535331_4	926569.ANT_11090	5.7e-86	296.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_535331_1	324602.Caur_1152	5.844e-145	462.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3750H@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD2_k127_535331_0	926550.CLDAP_18310	3.174e-167	530.0	COG0444@1|root,COG0444@2|Bacteria,2G5ST@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD2_k127_535331_3	926550.CLDAP_18300	2.374e-111	362.0	COG1173@1|root,COG1173@2|Bacteria,2G648@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GZD2_k127_5355735_3	552811.Dehly_1213	4.554e-59	221.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5355735_7	1125971.ASJB01000015_gene5583	0.0002545	51.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4DZCI@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD2_k127_5355735_0	383372.Rcas_0084	7.525e-163	518.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_5355735_4	926569.ANT_17460	3.279e-44	178.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117,ko:K17318	ko02010,map02010	M00196,M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_5355735_1	926569.ANT_27830	1.005e-96	330.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GZD2_k127_5355735_6	243365.CV_0246	0.0001799	49.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,2KRRT@206351|Neisseriales	206351|Neisseriales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_5355735_2	926569.ANT_06830	4e-61	216.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GZD2_k127_5355735_5	926569.ANT_06840	5.005e-17	82.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
GZD2_k127_536093_1	877455.Metbo_0186	1.035e-97	333.0	COG2239@1|root,arCOG00634@2157|Archaea,2XWIB@28890|Euryarchaeota,23PEC@183925|Methanobacteria	183925|Methanobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
GZD2_k127_536093_2	521460.Athe_0657	5.175e-86	300.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD2_k127_536093_0	926569.ANT_07590	3.42e-219	693.0	COG4986@1|root,COG4986@2|Bacteria,2G5UN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GZD2_k127_5369331_0	926569.ANT_29200	1.225e-215	683.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GZD2_k127_5375468_0	1313301.AUGC01000001_gene1467	3.935e-107	362.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
GZD2_k127_5375468_1	746697.Aeqsu_1810	3.791e-78	269.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_5392553_0	926569.ANT_25570	1.562e-282	885.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GZD2_k127_5392553_6	1033744.CAEL01000023_gene279	8.84e-43	160.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,22HFM@1570339|Peptoniphilaceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
GZD2_k127_5392553_2	926550.CLDAP_11120	7.007e-135	436.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD2_k127_5392553_1	765420.OSCT_0589	1.563e-144	465.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD2_k127_5392553_3	243274.THEMA_02390	5.99e-123	419.0	COG0747@1|root,COG0747@2|Bacteria,2GC5G@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_5392553_4	443254.Marpi_1967	7.056e-110	365.0	COG0601@1|root,COG0601@2|Bacteria,2GBX3@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD2_k127_5392553_5	416591.Tlet_0649	2.838e-87	301.0	COG1173@1|root,COG1173@2|Bacteria,2GCHA@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GZD2_k127_5392553_7	319003.Bra1253DRAFT_06554	3.317e-06	57.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JVV3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
GZD2_k127_5402568_4	1122609.AUGT01000021_gene1190	5.015e-14	76.0	2DM3D@1|root,31J5I@2|Bacteria,2I578@201174|Actinobacteria,4DWXX@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
GZD2_k127_5402568_5	5911.EAR85563	1.191e-07	63.0	2CN9Y@1|root,2QUR8@2759|Eukaryota	5911.EAR85563|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5402568_0	518766.Rmar_2786	4.926e-170	545.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1FJBY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
GZD2_k127_5402568_1	1356852.N008_16470	2.674e-43	164.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD2_k127_5402568_3	1385520.N802_13230	4.439e-17	86.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_5402568_2	1278073.MYSTI_01271	1.912e-21	97.0	COG2378@1|root,COG2378@2|Bacteria,1R98A@1224|Proteobacteria,42VBY@68525|delta/epsilon subdivisions,2WRWU@28221|Deltaproteobacteria,2YU1N@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
GZD2_k127_5406132_2	926550.CLDAP_15720	1.193e-48	180.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi	200795|Chloroflexi	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GZD2_k127_5406132_0	1173028.ANKO01000139_gene671	1.231e-66	242.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
GZD2_k127_5406132_4	290315.Clim_2386	1.306e-32	132.0	2C8DW@1|root,32RKY@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF3597)	MA20_41375	-	-	-	-	-	-	-	-	-	-	-	DUF3597
GZD2_k127_5406132_3	926569.ANT_18860	2.199e-46	170.0	COG3743@1|root,COG3743@2|Bacteria,2G96D@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
GZD2_k127_5406132_1	1191523.MROS_1373	7.483e-49	178.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD2_k127_5410640_0	935948.KE386495_gene1868	1.249e-179	576.0	COG3664@1|root,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,42FZX@68295|Thermoanaerobacterales	186801|Clostridia	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Glyco_hydro_39,HTH_18
GZD2_k127_5410640_2	452637.Oter_0662	1.347e-97	327.0	COG4975@1|root,COG4975@2|Bacteria	2|Bacteria	G	carbohydrate transmembrane transporter activity	glcU	GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659	-	ko:K05340,ko:K06216	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Sugar_transport,Ureide_permease
GZD2_k127_5410640_8	1450694.BTS2_3923	1.694e-09	67.0	COG1595@1|root,COG1595@2|Bacteria,1VCHT@1239|Firmicutes,4HX1M@91061|Bacilli,1ZH9M@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_5410640_1	926569.ANT_01730	5.346e-168	537.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_5410640_4	457396.CSBG_02776	7.397e-48	174.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,36JND@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
GZD2_k127_5410640_5	368407.Memar_2285	1.797e-37	148.0	arCOG00346@1|root,arCOG00346@2157|Archaea,2XU0A@28890|Euryarchaeota	28890|Euryarchaeota	S	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
GZD2_k127_5410640_6	266117.Rxyl_2945	3.509e-18	87.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD2_k127_5410640_3	926569.ANT_26870	1.197e-84	287.0	COG1432@1|root,COG1432@2|Bacteria,2G7FS@200795|Chloroflexi	200795|Chloroflexi	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
GZD2_k127_5417896_3	926569.ANT_14090	9.618e-24	102.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
GZD2_k127_5417896_1	1173025.GEI7407_0489	7.456e-133	431.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1H8R3@1150|Oscillatoriales	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5417896_0	926569.ANT_28010	2.276e-221	694.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
GZD2_k127_5417896_2	357808.RoseRS_2964	6.798e-79	271.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
GZD2_k127_5418064_2	649831.L083_2743	1.629e-35	141.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4D984@85008|Micromonosporales	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GZD2_k127_5418064_0	1121377.KB906402_gene3271	3.572e-185	595.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD2_k127_5418064_1	391037.Sare_1461	9.318e-113	382.0	2EXXE@1|root,33R6H@2|Bacteria,2H1T6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5493013_2	1499967.BAYZ01000179_gene4623	1.213e-53	198.0	29FVD@1|root,302T2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5493013_1	926569.ANT_18530	2.303e-60	211.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GZD2_k127_5493013_0	926550.CLDAP_06250	1.546e-93	322.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
GZD2_k127_5493013_3	85982.XP_007322981.1	1.954e-08	64.0	KOG4351@1|root,KOG4351@2759|Eukaryota,39JVV@33154|Opisthokonta,3Q484@4751|Fungi,3V7DN@5204|Basidiomycota,22FG0@155619|Agaricomycetes	4751|Fungi	DZ	Ig-like domain from next to BRCA1 gene	-	-	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,ZZ
GZD2_k127_5494929_5	1077972.ARGLB_064_00320	4.008e-88	299.0	COG3591@1|root,COG3591@2|Bacteria,2I3KX@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
GZD2_k127_5494929_0	1386089.N865_09795	0.0	1104.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4FG03@85021|Intrasporangiaceae	201174|Actinobacteria	S	Immune inhibitor A peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
GZD2_k127_5494929_6	357808.RoseRS_1515	1.03e-11	71.0	2DRD4@1|root,33B9X@2|Bacteria,2G9Z1@200795|Chloroflexi,377FH@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5494929_4	1280390.CBQR020000071_gene1478	1.106e-141	474.0	COG4412@1|root,COG4412@2|Bacteria,1TQYP@1239|Firmicutes,4HD82@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
GZD2_k127_5494929_1	290397.Adeh_0829	6.778e-306	953.0	COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
GZD2_k127_5494929_3	1172188.KB911829_gene4456	8.144e-211	673.0	COG4409@1|root,COG4409@2|Bacteria,2IEMG@201174|Actinobacteria,4FITI@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5494929_2	1386089.N865_10585	3.534e-301	936.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Calx-beta,DUF4214,HemolysinCabind,SdrD_B
GZD2_k127_5503387_3	1499967.BAYZ01000033_gene1106	1.87e-35	137.0	COG3382@1|root,COG3382@2|Bacteria	2|Bacteria	J	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
GZD2_k127_5503387_1	398578.Daci_4375	1.044e-64	224.0	COG1670@1|root,COG1670@2|Bacteria,1REQ5@1224|Proteobacteria,2W22N@28216|Betaproteobacteria,4AHHT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_5503387_0	316274.Haur_1815	1.201e-158	524.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi,377ZW@32061|Chloroflexia	32061|Chloroflexia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
GZD2_k127_5503387_4	316274.Haur_1815	1.03e-32	131.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi,377ZW@32061|Chloroflexia	32061|Chloroflexia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
GZD2_k127_5503387_2	402777.KB235903_gene2505	7.96e-58	208.0	COG0726@1|root,COG0726@2|Bacteria,1G02J@1117|Cyanobacteria,1H87V@1150|Oscillatoriales	1117|Cyanobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD2_k127_5504601_1	42256.RradSPS_0358	7.526e-210	665.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GZD2_k127_5504601_3	765420.OSCT_0941	2.525e-75	262.0	COG4279@1|root,COG4279@2|Bacteria,2G7AI@200795|Chloroflexi	200795|Chloroflexi	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
GZD2_k127_5504601_0	1123508.JH636439_gene662	1.384e-257	827.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
GZD2_k127_5504601_5	1121920.AUAU01000007_gene543	0.0005913	44.0	COG0604@1|root,COG0604@2|Bacteria,3Y4X4@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_5504601_4	485913.Krac_9312	7.938e-38	150.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,DUF3335,PG_binding_1,Peptidase_C39_2,Peptidase_C70,VCBS
GZD2_k127_5504601_2	926569.ANT_13110	2.019e-85	296.0	COG0787@1|root,COG0787@2|Bacteria,2G66N@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD2_k127_5516546_0	981384.AEYW01000001_gene1562	4.461e-240	790.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
GZD2_k127_5516546_2	237368.SCABRO_00762	5.395e-29	130.0	28I4Y@1|root,2Z88D@2|Bacteria,2J2FV@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5516546_1	1173028.ANKO01000126_gene4119	9.925e-211	675.0	COG0515@1|root,COG0642@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase,SpoIIE
GZD2_k127_5530164_2	1267211.KI669560_gene562	9.431e-14	84.0	COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5530164_0	562970.Btus_2406	4.43e-112	386.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,278ZI@186823|Alicyclobacillaceae	91061|Bacilli	C	Domain of unknown function (DUF3390)	yvfW	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
GZD2_k127_5530164_1	926560.KE387023_gene2224	2.729e-63	224.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
GZD2_k127_5587167_1	1197130.BAFM01000010_gene1848	4.593e-32	131.0	COG2820@1|root,arCOG01324@2157|Archaea,2Y06F@28890|Euryarchaeota,23W2X@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
GZD2_k127_5587167_0	497964.CfE428DRAFT_0631	2.892e-139	476.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
GZD2_k127_5626097_5	402777.KB235904_gene3693	9.117e-60	209.0	COG1063@1|root,COG1063@2|Bacteria,1G26C@1117|Cyanobacteria,1H92J@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
GZD2_k127_5626097_8	204773.HEAR2140	7.083e-23	101.0	COG1359@1|root,COG1359@2|Bacteria,1NG3M@1224|Proteobacteria,2W4IR@28216|Betaproteobacteria,477TI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD2_k127_5626097_10	479434.Sthe_0281	2.568e-19	95.0	COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi,27YAI@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GZD2_k127_5626097_7	926569.ANT_19700	6.577e-23	105.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD2_k127_5626097_2	1287276.X752_22365	1.731e-88	304.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,2TSH8@28211|Alphaproteobacteria,43MYJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GZD2_k127_5626097_3	886377.Murru_1453	1.404e-73	253.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
GZD2_k127_5626097_6	324602.Caur_2581	9.997e-35	138.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5626097_4	326427.Cagg_2787	7.916e-66	233.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GZD2_k127_5626097_9	292459.STH2564	1.055e-21	100.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
GZD2_k127_5626097_0	926569.ANT_16690	3.711e-123	407.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GZD2_k127_5626097_1	926569.ANT_16680	7.967e-106	350.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GZD2_k127_5642156_0	926569.ANT_15250	8.654e-213	673.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
GZD2_k127_5642156_1	1244869.H261_09217	3.935e-93	317.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,2TRNC@28211|Alphaproteobacteria,2JVTD@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_5642156_2	926569.ANT_19910	2.603e-22	98.0	COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi	200795|Chloroflexi	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
GZD2_k127_5644482_0	1173023.KE650771_gene5309	1.764e-158	524.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,1JJ7J@1189|Stigonemataceae	1117|Cyanobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
GZD2_k127_5644482_4	743721.Psesu_0858	8.191e-05	48.0	2EU9B@1|root,33MRR@2|Bacteria,1PBGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5644482_1	926550.CLDAP_13010	2.841e-43	169.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
GZD2_k127_5644482_3	926569.ANT_17670	1.626e-23	101.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD2_k127_5714583_0	926569.ANT_18650	5.583e-127	414.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_5714583_1	926569.ANT_18660	1.103e-67	239.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
GZD2_k127_571936_3	743719.PaelaDRAFT_4461	1.561e-57	217.0	COG2182@1|root,COG2182@2|Bacteria,1UMDK@1239|Firmicutes,4IU3T@91061|Bacilli,277I7@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
GZD2_k127_571936_0	926550.CLDAP_13320	1.225e-92	316.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
GZD2_k127_571936_1	751945.Theos_0473	8.761e-91	310.0	COG0438@1|root,COG0438@2|Bacteria,1WIJ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_571936_2	743299.Acife_1168	4.848e-77	269.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,2NDKS@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_571936_4	331113.SNE_A02330	6.661e-15	86.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
GZD2_k127_571961_0	926569.ANT_07670	4.251e-67	241.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD2_k127_571961_1	477974.Daud_0551	3.758e-07	55.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,260CB@186807|Peptococcaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
GZD2_k127_5722298_0	926569.ANT_20650	1.082e-232	727.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
GZD2_k127_5722298_1	926569.ANT_20640	1.081e-156	504.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
GZD2_k127_5722298_9	926569.ANT_20630	4.962e-57	213.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
GZD2_k127_5722298_2	926569.ANT_11580	2.143e-110	366.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
GZD2_k127_5722298_8	479434.Sthe_1615	4.244e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_5722298_5	926569.ANT_11560	4.585e-96	332.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_5722298_6	926569.ANT_26780	1.446e-60	214.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_5722298_4	555088.DealDRAFT_2880	6.057e-100	334.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD2_k127_5722298_7	941449.dsx2_0029	1.304e-59	218.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2M8R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_5722298_10	765420.OSCT_1688	1.235e-45	170.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GZD2_k127_5725168_2	926569.ANT_03640	2.471e-62	225.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GZD2_k127_5725168_0	926569.ANT_03630	2.349e-109	361.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
GZD2_k127_5725168_1	383372.Rcas_2663	2.339e-76	287.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
GZD2_k127_5725168_3	1121406.JAEX01000001_gene354	9.565e-34	151.0	COG2202@1|root,COG3829@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,42SMY@68525|delta/epsilon subdivisions,2WPKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,PAS
GZD2_k127_5746137_1	926569.ANT_06740	1.99e-83	285.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
GZD2_k127_5746137_0	926569.ANT_05220	6.658e-232	729.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GZD2_k127_5748304_2	926569.ANT_22520	3.705e-33	131.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GZD2_k127_5748304_1	926569.ANT_22530	3.26e-45	172.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
GZD2_k127_5748304_0	765420.OSCT_3068	8.893e-79	274.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GZD2_k127_5748981_0	926569.ANT_03530	0.0	1109.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GZD2_k127_5750992_1	926569.ANT_22810	8.05e-65	223.0	COG0588@1|root,COG0588@2|Bacteria,2G822@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GZD2_k127_5750992_2	1499967.BAYZ01000008_gene5415	1.369e-46	176.0	COG3551@1|root,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,TPR_19
GZD2_k127_5750992_0	234267.Acid_6181	5.815e-68	248.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_5752059_4	926569.ANT_23310	2.604e-106	351.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GZD2_k127_5752059_2	926569.ANT_23330	4.193e-159	519.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GZD2_k127_5752059_0	926569.ANT_23340	1.955e-195	619.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD2_k127_5752059_3	926569.ANT_23350	5.876e-147	473.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GZD2_k127_5752059_1	926569.ANT_23360	1.31e-182	582.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GZD2_k127_5752059_5	309801.trd_0062	5.137e-62	229.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,27XXN@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GZD2_k127_5754979_7	316274.Haur_1489	1.478e-12	73.0	COG5002@1|root,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3752Y@32061|Chloroflexia	32061|Chloroflexia	T	Integral membrane sensor signal transduction histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
GZD2_k127_5754979_2	1128421.JAGA01000003_gene3537	2.452e-90	304.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_5754979_1	1382306.JNIM01000001_gene3067	5.637e-137	461.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_5754979_0	926569.ANT_07930	2.502e-150	487.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD2_k127_5754979_3	926569.ANT_07920	3.455e-86	292.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_5754979_5	1042163.BRLA_c008440	3.71e-17	95.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	hlyD3	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD2_k127_5754979_4	926569.ANT_07910	1.973e-40	168.0	COG0845@1|root,COG0845@2|Bacteria,2G8US@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD2_k127_5754979_8	1232453.BAIF02000032_gene2602	3.225e-11	67.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD2_k127_5758061_4	526218.Sterm_2959	6.061e-34	138.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celG	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
GZD2_k127_5758061_2	335541.Swol_1899	7.156e-83	290.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
GZD2_k127_5758061_5	935948.KE386494_gene995	8.056e-08	55.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,42FH9@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
GZD2_k127_5758061_3	1227739.Hsw_1331	1.521e-68	244.0	COG3325@1|root,COG3325@2|Bacteria,4NNUM@976|Bacteroidetes,47PUW@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
GZD2_k127_5758061_6	1410634.JHVD01000001_gene1525	2.341e-06	60.0	COG1653@1|root,COG1653@2|Bacteria,2GKM8@201174|Actinobacteria,4DQWX@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17329	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_5758061_1	926569.ANT_11070	3.418e-86	299.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GZD2_k127_5758061_0	926569.ANT_11080	3.805e-133	432.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GZD2_k127_5764566_1	1120973.AQXL01000119_gene533	3.615e-83	289.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,279NS@186823|Alicyclobacillaceae	91061|Bacilli	L	IMS family HHH motif	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GZD2_k127_5764566_0	158190.SpiGrapes_1961	1.823e-106	355.0	28PJ3@1|root,2ZC8W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_576639_0	926569.ANT_11800	1.653e-94	344.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_576639_2	1121441.AUCX01000007_gene1056	2.171e-05	58.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X6YR@28221|Deltaproteobacteria,2MH8N@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_1
GZD2_k127_576639_1	926569.ANT_11800	2.268e-21	100.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
GZD2_k127_5767521_3	926569.ANT_23460	9.179e-109	356.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GZD2_k127_5767521_0	926569.ANT_23450	2.501e-178	566.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GZD2_k127_5767521_1	926569.ANT_23430	7.676e-145	467.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GZD2_k127_5767521_2	926569.ANT_23420	5.457e-109	361.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GZD2_k127_5768027_2	1382306.JNIM01000001_gene3678	1.092e-43	164.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
GZD2_k127_5768027_1	998674.ATTE01000001_gene3785	7.048e-56	202.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD2_k127_5768027_3	1499967.BAYZ01000078_gene980	2.658e-13	76.0	2DFUU@1|root,2ZT8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5768027_0	926569.ANT_13200	1.322e-183	582.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
GZD2_k127_5768027_4	926569.ANT_28120	3.597e-07	60.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
GZD2_k127_5768273_2	926569.ANT_04660	1.637e-21	94.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
GZD2_k127_5768273_3	1121428.DESHY_50115___1	8.502e-19	99.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,260JD@186807|Peptococcaceae	186801|Clostridia	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD2_k127_5768273_1	926569.ANT_04670	1.359e-174	558.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_5768273_4	640081.Dsui_2088	0.0003803	51.0	COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,2VJUY@28216|Betaproteobacteria,2KW18@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3
GZD2_k127_5768273_0	926569.ANT_14810	2.377e-308	958.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GZD2_k127_5786010_3	926569.ANT_30130	1.665e-13	77.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GZD2_k127_5786010_0	926569.ANT_03580	2.621e-95	334.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5786010_1	926569.ANT_04450	4.223e-63	222.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
GZD2_k127_5786010_2	926569.ANT_04460	4.94e-39	151.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GZD2_k127_5799633_1	326427.Cagg_0510	3.508e-109	359.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi,376PA@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
GZD2_k127_5799633_0	309801.trd_0142	1.276e-132	432.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
GZD2_k127_5799633_3	309801.trd_0143	5.756e-51	184.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GZD2_k127_5799633_2	309801.trd_0144	1.015e-57	204.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GZD2_k127_5799633_4	309801.trd_0145	4.857e-27	112.0	28XG9@1|root,2ZJDS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5799633_5	309801.trd_0147	5.776e-10	61.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi,27YVD@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
GZD2_k127_5802577_1	1541065.JRFE01000026_gene2122	4.492e-43	160.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
GZD2_k127_5802577_2	370438.PTH_1831	1.707e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_5802577_0	706587.Desti_1188	9.529e-93	311.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42Q5R@68525|delta/epsilon subdivisions,2WM6U@28221|Deltaproteobacteria,2MR4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
GZD2_k127_5802577_3	443143.GM18_0493	1.089e-22	99.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Chromate	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
GZD2_k127_5821264_0	1123073.KB899242_gene1521	7.873e-100	336.0	COG1807@1|root,COG1807@2|Bacteria,1N57T@1224|Proteobacteria,1TD24@1236|Gammaproteobacteria,1X9YF@135614|Xanthomonadales	135614|Xanthomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_5843498_0	997884.HMPREF1068_03310	1.799e-129	427.0	COG0463@1|root,COG0463@2|Bacteria,4P0I4@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_5843498_2	197221.22296046	8.853e-27	121.0	COG1216@1|root,COG1216@2|Bacteria,1G8YE@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_5843498_3	323259.Mhun_0391	4.076e-08	57.0	COG0438@1|root,arCOG01410@2157|Archaea,2XYAQ@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD2_k127_5843498_1	1191523.MROS_2178	2.779e-63	220.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_5866656_0	926569.ANT_08430	1.826e-77	267.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi	200795|Chloroflexi	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
GZD2_k127_5866656_1	926569.ANT_08470	4.971e-69	250.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
GZD2_k127_5866656_3	926569.ANT_08490	2.336e-47	175.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GZD2_k127_5868439_1	468059.AUHA01000002_gene898	3.916e-169	541.0	COG0467@1|root,COG0467@2|Bacteria,4NKD2@976|Bacteroidetes,1IV5Y@117747|Sphingobacteriia	976|Bacteroidetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GZD2_k127_5868439_3	335543.Sfum_0084	1.553e-23	104.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GZD2_k127_5868439_0	1040986.ATYO01000002_gene3904	2.515e-191	609.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
GZD2_k127_5868439_4	1487921.DP68_07680	1.668e-12	78.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,36EWT@31979|Clostridiaceae	186801|Clostridia	O	SPFH domain Band 7 family	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
GZD2_k127_5868439_2	497964.CfE428DRAFT_6158	5.877e-49	179.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S9A@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
GZD2_k127_5868678_2	1123368.AUIS01000005_gene461	9.907e-48	173.0	COG3300@1|root,COG4251@1|root,COG3300@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2NE6V@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GZD2_k127_5868678_1	292415.Tbd_1192	5.154e-58	205.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,1KT24@119069|Hydrogenophilales	119069|Hydrogenophilales	T	cheY-homologous receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GZD2_k127_5868678_0	886293.Sinac_4735	9.612e-133	445.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG5278@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,2IZHZ@203682|Planctomycetes	203682|Planctomycetes	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF,HD,Response_reg
GZD2_k127_5879618_4	357808.RoseRS_1320	4.596e-11	69.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GZD2_k127_5879618_1	1254432.SCE1572_44715	1.689e-116	384.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GZD2_k127_5879618_0	926569.ANT_28050	3.332e-167	535.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_5879618_2	926569.ANT_28060	5.603e-108	358.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GZD2_k127_5879618_3	926569.ANT_00870	1.435e-77	276.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
GZD2_k127_5884186_3	1313172.YM304_04440	3.169e-14	75.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
GZD2_k127_5884186_5	1121924.ATWH01000007_gene2148	1.092e-08	58.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria,4FQAR@85023|Microbacteriaceae	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
GZD2_k127_5884186_4	1404245.CGLY_05960	5.162e-12	72.0	2DPFE@1|root,331UR@2|Bacteria,2ISSB@201174|Actinobacteria,22NDA@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
GZD2_k127_5884186_2	485913.Krac_8476	3.352e-15	81.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
GZD2_k127_5884186_1	255470.cbdbA1612	3.204e-17	81.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_5888908_10	1235792.C808_01386	3.321e-09	59.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,27PJ6@186928|unclassified Lachnospiraceae	186801|Clostridia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GZD2_k127_5888908_12	1131462.DCF50_p234	6.948e-08	54.0	COG0535@1|root,COG0535@2|Bacteria,1V0CR@1239|Firmicutes,24BIB@186801|Clostridia,261UA@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GZD2_k127_5888908_8	266265.Bxe_B0352	4.227e-17	84.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2VU9A@28216|Betaproteobacteria,1K8KF@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD2_k127_5888908_3	643648.Slip_2188	2.28e-34	138.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,42K4C@68298|Syntrophomonadaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	DGC,GCV_H
GZD2_k127_5888908_6	643648.Slip_2187	1.835e-25	111.0	COG4273@1|root,COG4273@2|Bacteria,1VBRH@1239|Firmicutes,24N2C@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
GZD2_k127_5888908_2	643648.Slip_2186	2.344e-36	147.0	COG4273@1|root,COG4273@2|Bacteria,1UPTR@1239|Firmicutes,25HNZ@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
GZD2_k127_5888908_4	643648.Slip_2185	1.664e-33	134.0	COG1764@1|root,COG1764@2|Bacteria,1VYMJ@1239|Firmicutes,2538T@186801|Clostridia	186801|Clostridia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
GZD2_k127_5888908_7	926569.ANT_21130	7.279e-25	106.0	COG0526@1|root,COG0526@2|Bacteria,2G7HI@200795|Chloroflexi	200795|Chloroflexi	CO	TIGRFAM redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GZD2_k127_5888908_9	1288826.MSNKSG1_13602	5.467e-12	70.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria,468CW@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GZD2_k127_5888908_13	324602.Caur_0013	5.483e-07	56.0	COG0640@1|root,COG0640@2|Bacteria,2GB64@200795|Chloroflexi,377ES@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD2_k127_5888908_5	913865.DOT_5223	5.235e-26	112.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2632C@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GZD2_k127_5888908_11	1499967.BAYZ01000050_gene2856	2.801e-08	60.0	290BJ@1|root,2ZN13@2|Bacteria	2|Bacteria	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
GZD2_k127_5888908_14	1410619.SRDD_00170	7.628e-06	50.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,402GJ@613|Serratia	1236|Gammaproteobacteria	C	[2Fe-2S] binding domain	xdhC	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13480	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_4158,iECSP_1301.ECSP_3838,iECs_1301.ECs3741,iZ_1308.Z4207	Fer2,Fer2_2
GZD2_k127_5888908_0	457570.Nther_2211	2.069e-47	179.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD2_k127_5888908_1	926550.CLDAP_40610	1.659e-39	152.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GZD2_k127_589294_6	382464.ABSI01000011_gene2976	3.825e-11	64.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_589294_4	1437425.CSEC_2042	5.653e-34	137.0	COG4403@1|root,COG4403@2|Bacteria,2JHAZ@204428|Chlamydiae	204428|Chlamydiae	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_589294_2	926569.ANT_29550	3.046e-73	259.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GZD2_k127_589294_1	926569.ANT_29560	1.141e-99	350.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
GZD2_k127_589294_3	926569.ANT_25500	8.685e-47	182.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_589294_5	926569.ANT_25500	1.722e-17	93.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_589294_0	926569.ANT_25510	1.132e-157	503.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
GZD2_k127_5907589_0	357808.RoseRS_2594	1.582e-165	527.0	COG1231@1|root,COG1231@2|Bacteria,2G942@200795|Chloroflexi	200795|Chloroflexi	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
GZD2_k127_5907589_1	102129.Lepto7375DRAFT_1904	4.236e-91	308.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1G3BJ@1117|Cyanobacteria,1H9DG@1150|Oscillatoriales	1117|Cyanobacteria	L	TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
GZD2_k127_5907589_2	1449050.JNLE01000003_gene2228	1.916e-76	267.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_5907589_3	926550.CLDAP_20700	6.206e-41	153.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_5910004_0	926569.ANT_18690	5.068e-118	380.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD2_k127_5910004_3	1051632.TPY_0753	3.084e-19	101.0	COG5542@1|root,COG5542@2|Bacteria,1V7KR@1239|Firmicutes,24IW1@186801|Clostridia	186801|Clostridia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
GZD2_k127_5910004_1	926569.ANT_11510	2.044e-99	342.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5910004_2	926569.ANT_05240	8.056e-90	300.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GZD2_k127_5912651_3	926569.ANT_18100	1.23e-96	318.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
GZD2_k127_5912651_2	670292.JH26_03925	2.442e-99	336.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TYK7@28211|Alphaproteobacteria,1JZHM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
GZD2_k127_5912651_0	1232410.KI421419_gene2455	8.679e-210	659.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,43UGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
GZD2_k127_5912651_4	649831.L083_2949	1.441e-05	56.0	COG2199@1|root,COG2199@2|Bacteria,2ICC1@201174|Actinobacteria,4DGXS@85008|Micromonosporales	201174|Actinobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
GZD2_k127_5912651_1	926569.ANT_18110	1.659e-127	420.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GZD2_k127_5917847_3	926569.ANT_11210	2.751e-29	118.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
GZD2_k127_5917847_4	927677.ALVU02000001_gene1334	1.383e-27	121.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD2_k127_5917847_1	457421.CBFG_05079	8.9e-42	163.0	COG3291@1|root,COG3291@2|Bacteria,1UJWM@1239|Firmicutes,25FCB@186801|Clostridia	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5917847_2	485913.Krac_3358	2.961e-39	150.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_5917847_0	926560.KE387023_gene1591	4.157e-60	211.0	COG0590@1|root,COG0590@2|Bacteria,1WMK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
GZD2_k127_5917847_6	243365.CV_3444	4.051e-16	81.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,2VWS3@28216|Betaproteobacteria,2KTBY@206351|Neisseriales	206351|Neisseriales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	-
GZD2_k127_5917847_5	871585.BDGL_000353	1.577e-18	94.0	2D8TI@1|root,32TRX@2|Bacteria,1N5N2@1224|Proteobacteria,1SRJP@1236|Gammaproteobacteria,3NN01@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5928580_2	215803.DB30_2247	7.638e-22	98.0	COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
GZD2_k127_5928580_4	530564.Psta_3285	2.387e-09	62.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GZD2_k127_5928580_0	660470.Theba_2258	1.358e-93	318.0	2EUJV@1|root,33N1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5928580_1	1294142.CINTURNW_2649	1.983e-41	155.0	COG0251@1|root,COG0251@2|Bacteria,1V41A@1239|Firmicutes,24HDA@186801|Clostridia,36K8H@31979|Clostridiaceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD2_k127_5928580_3	1210884.HG799469_gene14132	4.024e-13	69.0	COG0039@1|root,COG0039@2|Bacteria,2IYB4@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
GZD2_k127_59334_0	329726.AM1_2452	1.294e-240	791.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GZD2_k127_59334_7	395493.BegalDRAFT_1333	4.841e-25	109.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GZD2_k127_59334_5	290315.Clim_1053	3.915e-57	205.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
GZD2_k127_59334_6	1121920.AUAU01000006_gene266	4.313e-41	153.0	COG2329@1|root,COG2329@2|Bacteria,3Y5V2@57723|Acidobacteria	57723|Acidobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_59334_4	324602.Caur_0597	1.488e-62	218.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD2_k127_59334_3	861299.J421_6202	4.69e-124	406.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_59334_2	985665.HPL003_06625	6.172e-136	439.0	COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,26TIZ@186822|Paenibacillaceae	91061|Bacilli	E	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
GZD2_k127_59334_1	1449063.JMLS01000017_gene650	2.481e-171	547.0	COG0277@1|root,COG0277@2|Bacteria,1TS7V@1239|Firmicutes,4HC0H@91061|Bacilli,26VYC@186822|Paenibacillaceae	91061|Bacilli	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41,1.1.3.8	ko:K00103,ko:K00594	ko00040,ko00051,ko00053,ko01100,map00040,map00051,map00053,map01100	M00129	R00647,R03184,R07152,R10053,R11620	RC00108,RC00133,RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GZD2_k127_59334_8	1521187.JPIM01000139_gene2217	8.637e-14	76.0	COG1073@1|root,COG1073@2|Bacteria,2G73I@200795|Chloroflexi,375SM@32061|Chloroflexia	32061|Chloroflexia	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD2_k127_5937144_1	476272.RUMHYD_02343	9.01e-76	260.0	COG2070@1|root,COG2070@2|Bacteria,1VS86@1239|Firmicutes,25DQI@186801|Clostridia	186801|Clostridia	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5937144_3	485916.Dtox_1332	1.458e-45	168.0	COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,24JJN@186801|Clostridia,261YQ@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	adhR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
GZD2_k127_5937144_0	926550.CLDAP_24180	3.179e-153	491.0	COG0667@1|root,COG0667@2|Bacteria,2G7T1@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_5937144_2	1340493.JNIF01000004_gene223	2.663e-65	224.0	COG1917@1|root,COG1917@2|Bacteria,3Y4HX@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD2_k127_5941114_2	926569.ANT_15180	1.104e-41	156.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
GZD2_k127_5941114_0	765420.OSCT_1893	5.928e-119	389.0	COG0697@1|root,COG0697@2|Bacteria,2G9RG@200795|Chloroflexi,377CV@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_5941114_1	1510531.JQJJ01000008_gene3856	3.131e-43	166.0	COG3896@1|root,COG3896@2|Bacteria,1NX1Z@1224|Proteobacteria,2U3CG@28211|Alphaproteobacteria,3K41A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
GZD2_k127_5941114_3	1128421.JAGA01000002_gene800	3.659e-12	68.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11
GZD2_k127_5953320_1	926569.ANT_02230	8.775e-60	213.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GZD2_k127_5953320_2	926569.ANT_02240	2.458e-42	157.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GZD2_k127_5953320_0	926569.ANT_02250	2.017e-138	447.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GZD2_k127_5955264_0	926569.ANT_16920	3.921e-191	602.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
GZD2_k127_5955264_3	357808.RoseRS_0231	2.714e-53	214.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
GZD2_k127_5955264_1	926569.ANT_11740	6.26e-138	455.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi	200795|Chloroflexi	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
GZD2_k127_5955264_2	926569.ANT_11750	3.16e-56	204.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_5955264_4	926569.ANT_11760	9.614e-26	109.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_5959185_4	1382358.JHVN01000005_gene3032	1.053e-19	93.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4I3DV@91061|Bacilli,21VVU@150247|Anoxybacillus	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
GZD2_k127_5959185_0	926569.ANT_02050	5.835e-135	437.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi	200795|Chloroflexi	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
GZD2_k127_5959185_2	926569.ANT_03490	4.316e-59	216.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GZD2_k127_5959185_1	926569.ANT_03500	5.944e-111	362.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GZD2_k127_5959185_3	926569.ANT_03510	9.567e-59	206.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GZD2_k127_5963557_5	926569.ANT_27790	4.108e-24	104.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_5963557_3	765420.OSCT_1823	8.852e-61	228.0	2E0CW@1|root,32VZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5963557_2	926569.ANT_00470	6.214e-105	346.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD2_k127_5963557_0	926569.ANT_02270	3.655e-200	642.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
GZD2_k127_5963557_4	926569.ANT_02260	1.862e-36	140.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
GZD2_k127_5963557_1	926569.ANT_02250	5.618e-133	428.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GZD2_k127_5964329_2	926569.ANT_22850	2.393e-68	237.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GZD2_k127_5964329_5	1122169.AREN01000010_gene2585	1.979e-44	170.0	COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,1S88D@1236|Gammaproteobacteria,1JDWD@118969|Legionellales	118969|Legionellales	I	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	lidK	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GZD2_k127_5964329_7	926569.ANT_07460	4.286e-30	127.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
GZD2_k127_5964329_4	889378.Spiaf_2505	4.087e-47	177.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51,2.7.4.25	ko:K00655,ko:K00945	ko00240,ko00561,ko00564,ko01100,ko01110,map00240,map00561,map00564,map01100,map01110	M00052,M00089	R00158,R00512,R01665,R02241,R09381	RC00002,RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD2_k127_5964329_3	926569.ANT_14530	2.389e-60	214.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GZD2_k127_5964329_1	926569.ANT_15370	1.614e-94	327.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GZD2_k127_5964329_0	926569.ANT_16400	3.657e-162	526.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5964329_6	926569.ANT_16390	1.158e-43	163.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5964329_8	278957.ABEA03000112_gene1380	8.694e-09	59.0	COG1396@1|root,COG1396@2|Bacteria,46WYF@74201|Verrucomicrobia,3K9Q1@414999|Opitutae	414999|Opitutae	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GZD2_k127_5969329_0	273068.TTE1931	2.064e-111	394.0	2EWYX@1|root,33QA8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_5969329_1	485913.Krac_0894	9.88e-45	171.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD2_k127_597423_10	1460634.JCM19037_2800	3.592e-11	73.0	COG1595@1|root,COG1595@2|Bacteria,1V4T2@1239|Firmicutes,4HHRP@91061|Bacilli	91061|Bacilli	K	binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_597423_9	317936.Nos7107_0424	2.162e-12	73.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1HNCP@1161|Nostocales	1117|Cyanobacteria	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD2_k127_597423_13	358823.DF19_18065	5.235e-05	51.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD2_k127_597423_7	298654.FraEuI1c_3163	1.302e-20	108.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,DUF4394,PKD,Peptidase_M8
GZD2_k127_597423_11	580331.Thit_1132	2.814e-07	64.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25BB9@186801|Clostridia,42G9S@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_597423_2	1430440.MGMSRv2_2439	5.949e-75	281.0	COG1520@1|root,COG1520@2|Bacteria,1QV8R@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase activity	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,DUF4347,HYR,VCBS
GZD2_k127_597423_6	1237149.C900_00291	7.231e-45	168.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GZD2_k127_597423_4	1034769.KB910518_gene3027	1.079e-69	245.0	COG4886@1|root,COG4886@2|Bacteria,1UD7W@1239|Firmicutes,4HEKM@91061|Bacilli,2749P@186822|Paenibacillaceae	91061|Bacilli	S	Leucine-rich repeats, typical (most populated) subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,LRR_8,MucBP
GZD2_k127_597423_3	926550.CLDAP_08640	4.242e-70	243.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
GZD2_k127_597423_5	926550.CLDAP_08640	3.349e-51	184.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
GZD2_k127_597423_0	1403819.BATR01000053_gene1643	1.714e-82	281.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia,2IV5M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD2_k127_597423_12	5911.EAR82375	2.497e-06	60.0	2CYSW@1|root,2S679@2759|Eukaryota,3ZE4R@5878|Ciliophora	5878|Ciliophora	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GZD2_k127_597423_8	926569.ANT_31290	4.277e-17	94.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
GZD2_k127_597423_1	1173027.Mic7113_1368	9.401e-78	286.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,SpoIIE,TIR_2,WD40
GZD2_k127_5978654_0	926569.ANT_13710	1.169e-97	326.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
GZD2_k127_5978654_1	395961.Cyan7425_1562	5.72e-94	323.0	COG2114@1|root,COG2114@2|Bacteria,1G2T0@1117|Cyanobacteria,3KHFY@43988|Cyanothece	1117|Cyanobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GZD2_k127_5978654_2	926569.ANT_02540	3.018e-90	307.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GZD2_k127_6022164_4	926550.CLDAP_29040	9.399e-77	267.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
GZD2_k127_6022164_3	926569.ANT_09940	7.803e-80	269.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GZD2_k127_6022164_9	518766.Rmar_1910	4.866e-19	91.0	COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GZD2_k127_6022164_8	518766.Rmar_1910	4.419e-19	91.0	COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GZD2_k127_6022164_0	926569.ANT_09930	5.013e-102	350.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
GZD2_k127_6022164_6	926569.ANT_09920	1.47e-53	193.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_6022164_7	765420.OSCT_0605	1.438e-36	141.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi,374U5@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_6022164_1	926569.ANT_09910	4.527e-101	338.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GZD2_k127_6022164_5	926569.ANT_09900	8.624e-70	243.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GZD2_k127_6022164_2	926550.CLDAP_28330	2.499e-93	315.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GZD2_k127_6026555_1	1480694.DC28_07135	7.924e-41	160.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
GZD2_k127_6026555_0	926569.ANT_18200	4.735e-156	498.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
GZD2_k127_6041626_1	926569.ANT_25700	4.545e-25	117.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
GZD2_k127_6041626_0	926569.ANT_04370	1.796e-262	813.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GZD2_k127_6056261_2	323848.Nmul_A1020	9.691e-34	130.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2WBX2@28216|Betaproteobacteria,373YS@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GZD2_k127_6056261_1	1267535.KB906767_gene61	2.844e-150	482.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
GZD2_k127_6056261_0	472759.Nhal_2136	1.32e-204	655.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
GZD2_k127_605826_1	391612.CY0110_14003	2.086e-05	53.0	2E3GU@1|root,32YFI@2|Bacteria,1G9HI@1117|Cyanobacteria,3KIKQ@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_605826_0	65393.PCC7424_4056	9.196e-15	79.0	29Z9K@1|root,30M7T@2|Bacteria,1GM3Q@1117|Cyanobacteria,3KJ43@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
GZD2_k127_6059802_3	926569.ANT_19040	1.958e-22	98.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6059802_2	926569.ANT_19030	1.298e-93	311.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
GZD2_k127_6059802_1	1095769.CAHF01000006_gene1926	9.902e-107	351.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,476N7@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
GZD2_k127_6059802_0	926569.ANT_09340	1.787e-157	513.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_6071483_2	1347086.CCBA010000012_gene2030	8.377e-17	83.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6071483_0	926569.ANT_03450	1.498e-136	490.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
GZD2_k127_6071483_1	243274.THEMA_02295	1.289e-80	277.0	COG0162@1|root,COG0162@2|Bacteria,2GCKH@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iLJ478.TM0478	S4,tRNA-synt_1b
GZD2_k127_6086273_6	1200792.AKYF01000010_gene2349	8.874e-05	46.0	COG3393@1|root,COG3393@2|Bacteria,1V9KV@1239|Firmicutes,4HJ79@91061|Bacilli,26YGF@186822|Paenibacillaceae	91061|Bacilli	S	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
GZD2_k127_6086273_3	1089545.KB913037_gene8416	3.9e-23	109.0	COG1266@1|root,COG1266@2|Bacteria,2HRED@201174|Actinobacteria,4EAKF@85010|Pseudonocardiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD2_k127_6086273_0	485913.Krac_2537	9.733e-98	323.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_6086273_2	485913.Krac_10495	4.25e-43	172.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2G6PR@200795|Chloroflexi	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K11617	ko02020,ko02030,map02020,map02030	M00471,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3
GZD2_k127_6086273_1	269799.Gmet_1468	4.66e-64	231.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,4338I@68525|delta/epsilon subdivisions,2WXBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_6086273_4	926569.ANT_25540	4.762e-18	87.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GZD2_k127_6086273_5	365044.Pnap_0820	9.603e-17	82.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,4AGM6@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GZD2_k127_6087805_0	1463821.JOGR01000004_gene2545	4.091e-71	269.0	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,2H2SD@201174|Actinobacteria,4EZJH@85014|Glycomycetales	201174|Actinobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VRP1
GZD2_k127_6087805_2	1232410.KI421426_gene1430	3.653e-45	182.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
GZD2_k127_6087805_3	156889.Mmc1_1491	6.938e-10	64.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657,ko:K07659,ko:K18144	ko01501,ko02020,ko02026,map01501,map02020,map02026	M00434,M00445,M00649,M00655,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_6087805_4	383372.Rcas_2866	4.058e-07	55.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
GZD2_k127_6087805_1	762903.Pedsa_0641	2.644e-48	178.0	COG0262@1|root,COG0262@2|Bacteria,4NMP3@976|Bacteroidetes	976|Bacteroidetes	H	Pfam RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
GZD2_k127_6093440_3	1173028.ANKO01000017_gene231	6.044e-117	383.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GZD2_k127_6093440_0	926569.ANT_22400	6.438e-263	824.0	COG3533@1|root,COG3533@2|Bacteria,2G7X9@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
GZD2_k127_6093440_4	246194.CHY_0833	1.059e-59	213.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,42FEQ@68295|Thermoanaerobacterales	186801|Clostridia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
GZD2_k127_6093440_1	926569.ANT_15720	4.767e-155	503.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GZD2_k127_6093440_6	555079.Toce_0227	2.379e-41	156.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6093440_5	926569.ANT_15730	4.936e-53	196.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
GZD2_k127_6099539_8	926569.ANT_03460	2.663e-30	121.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD2_k127_6099539_2	1382306.JNIM01000001_gene79	8.246e-92	317.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
GZD2_k127_6099539_4	926569.ANT_11280	2.858e-47	178.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GZD2_k127_6099539_3	926569.ANT_11270	1.419e-90	304.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
GZD2_k127_6099539_7	640511.BC1002_6648	5.483e-33	139.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VNGN@28216|Betaproteobacteria,1K0ZX@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_6099539_9	981369.JQMJ01000004_gene1732	3.063e-22	104.0	COG4221@1|root,COG4221@2|Bacteria,2I2Z8@201174|Actinobacteria,2NF2P@228398|Streptacidiphilus	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_6099539_1	1254432.SCE1572_28920	2.818e-107	355.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
GZD2_k127_6099539_5	1094980.Mpsy_2065	3.227e-47	178.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM bifunctional deaminase-reductase domain protein	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
GZD2_k127_6099539_0	926550.CLDAP_28320	7.917e-144	475.0	COG0699@1|root,COG0699@2|Bacteria,2G5JQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dynamin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
GZD2_k127_6099539_6	32057.KB217472_gene7872	1.186e-36	158.0	COG1075@1|root,COG1361@1|root,COG1572@1|root,COG2931@1|root,COG1075@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
GZD2_k127_6099539_10	373994.Riv7116_0714	3.028e-13	81.0	COG0515@1|root,COG0515@2|Bacteria,1G0B6@1117|Cyanobacteria,1HJV7@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_6105442_2	765420.OSCT_3196	4.063e-65	240.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_6105442_3	373903.Hore_11920	5.387e-41	162.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WAKZ@53433|Halanaerobiales	186801|Clostridia	S	TIGRFAM competence damage-inducible protein CinA	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
GZD2_k127_6105442_0	926550.CLDAP_09870	1.636e-188	605.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
GZD2_k127_6105442_1	926550.CLDAP_06990	4.931e-81	276.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GZD2_k127_6120911_5	383372.Rcas_0225	8.37e-72	250.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
GZD2_k127_6120911_4	357808.RoseRS_0609	9.278e-75	264.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,375JB@32061|Chloroflexia	32061|Chloroflexia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GZD2_k127_6120911_2	926569.ANT_23190	2.456e-112	378.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
GZD2_k127_6120911_1	926569.ANT_23180	7.956e-132	433.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GZD2_k127_6120911_0	383372.Rcas_4054	6.451e-180	573.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_6120911_7	335543.Sfum_3561	4.787e-62	218.0	COG0317@1|root,COG0317@2|Bacteria,1RCK7@1224|Proteobacteria,42SEV@68525|delta/epsilon subdivisions,2WPK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
GZD2_k127_6120911_6	926569.ANT_18610	1.428e-69	245.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_6120911_3	926569.ANT_13730	4.431e-102	337.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GZD2_k127_6120911_8	568816.Acin_0760	5.895e-24	104.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,4H40U@909932|Negativicutes	909932|Negativicutes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GZD2_k127_6124725_2	111781.Lepto7376_0820	1.695e-54	209.0	COG1750@1|root,COG1750@2|Bacteria,1G9TZ@1117|Cyanobacteria	1117|Cyanobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
GZD2_k127_6124725_0	926569.ANT_13300	4.456e-201	637.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
GZD2_k127_6124725_1	316274.Haur_4751	2.054e-129	426.0	COG1164@1|root,COG1164@2|Bacteria,2G5UV@200795|Chloroflexi,376XT@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD2_k127_6125135_0	357808.RoseRS_0214	4.485e-206	647.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
GZD2_k127_6125135_4	290315.Clim_1904	8.316e-09	59.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
GZD2_k127_6125135_3	443143.GM18_0752	1.896e-11	66.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_6125135_1	926569.ANT_01840	3.089e-129	420.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GZD2_k127_6125135_2	742817.HMPREF9449_02474	1.742e-128	414.0	COG0205@1|root,COG0205@2|Bacteria,4NFPT@976|Bacteroidetes,2FMJ9@200643|Bacteroidia,22ZT1@171551|Porphyromonadaceae	976|Bacteroidetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GZD2_k127_6127972_1	236814.IX39_10950	4.237e-32	132.0	2CCY9@1|root,32W6X@2|Bacteria,4P5V3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6127972_0	306281.AJLK01000102_gene3405	7.781e-69	238.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6127972_4	56780.SYN_01159	0.0002274	44.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_6140960_7	926569.ANT_10920	3.363e-06	50.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GZD2_k127_6140960_4	525904.Tter_0583	8.814e-35	143.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
GZD2_k127_6140960_3	926569.ANT_10910	2.334e-45	178.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GZD2_k127_6140960_2	1131269.AQVV01000004_gene636	2.468e-54	205.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GZD2_k127_6140960_0	1307761.L21SP2_1483	2.662e-102	339.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
GZD2_k127_6140960_1	867903.ThesuDRAFT_00782	5.438e-68	256.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
GZD2_k127_6153718_0	1463921.JODF01000002_gene3096	1.803e-231	761.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
GZD2_k127_6153718_3	35754.JNYJ01000028_gene6111	7.585e-19	98.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DBPZ@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
GZD2_k127_6153718_2	1265505.ATUG01000002_gene1171	3.353e-56	210.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
GZD2_k127_6153718_1	768670.Calni_0847	1.011e-136	451.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,2GG9I@200930|Deferribacteres	200930|Deferribacteres	G	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
GZD2_k127_6154662_1	1535287.JP74_03050	1.562e-95	322.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3N64F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prsA	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
GZD2_k127_6154662_5	1521187.JPIM01000015_gene3744	1.251e-34	136.0	COG3339@1|root,COG3339@2|Bacteria,2G7DT@200795|Chloroflexi,377Q4@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GZD2_k127_6154662_2	926567.TheveDRAFT_1630	1.415e-53	196.0	COG1528@1|root,COG1528@2|Bacteria,3TB3G@508458|Synergistetes	508458|Synergistetes	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
GZD2_k127_6154662_4	1122221.JHVI01000014_gene1365	3.468e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
GZD2_k127_6154662_3	321327.CYA_2243	6.832e-51	186.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GZD2_k127_6154662_0	246197.MXAN_0891	1.862e-97	329.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,43BHV@68525|delta/epsilon subdivisions,2X6WB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
GZD2_k127_6157808_0	926569.ANT_31720	6.698e-309	952.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GZD2_k127_6157808_1	515620.EUBELI_01878	6.697e-28	115.0	COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,24N2G@186801|Clostridia,25ZGS@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD2_k127_6157808_2	1071073.KI530550_gene3619	1.521e-05	52.0	COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,1ZBNX@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6168810_6	926569.ANT_10270	9.374e-13	68.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GZD2_k127_6168810_1	926569.ANT_10260	1.757e-111	365.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GZD2_k127_6168810_2	926569.ANT_10250	6.137e-83	280.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
GZD2_k127_6168810_0	926569.ANT_10240	3.794e-155	502.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
GZD2_k127_6168810_4	926569.ANT_10230	7.485e-55	197.0	COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
GZD2_k127_6168810_5	1430440.MGMSRv2_0056	1.426e-15	78.0	COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,2JTU5@204441|Rhodospirillales	204441|Rhodospirillales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
GZD2_k127_6168810_3	926569.ANT_10210	9.622e-75	254.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
GZD2_k127_6199869_8	926569.ANT_14510	0.0001659	51.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD2_k127_6199869_0	926569.ANT_14490	9.114e-186	591.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GZD2_k127_6199869_4	926569.ANT_20600	2.823e-42	162.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6199869_1	555779.Dthio_PD2814	3.789e-177	561.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2M98D@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GZD2_k127_6199869_6	234267.Acid_3903	5.609e-16	80.0	2CC1B@1|root,32RUI@2|Bacteria,3Y56C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6199869_2	926569.ANT_11610	7.109e-44	165.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
GZD2_k127_6199869_5	926550.CLDAP_07840	1.985e-26	119.0	2DUZD@1|root,33T56@2|Bacteria,2G7Z6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6199869_3	485916.Dtox_1078	1.227e-42	170.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GZD2_k127_6216124_0	926569.ANT_12010	8.512e-142	457.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GZD2_k127_6216124_1	926569.ANT_12000	3.705e-85	289.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GZD2_k127_6216263_4	926569.ANT_08350	6.068e-119	397.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GZD2_k127_6216263_6	671143.DAMO_2695	2.427e-100	340.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GZD2_k127_6216263_7	926569.ANT_08370	1.826e-77	262.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GZD2_k127_6216263_14	926569.ANT_08380	4.88e-32	132.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD2_k127_6216263_15	324602.Caur_2906	1.131e-31	126.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia	32061|Chloroflexia	F	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GZD2_k127_6216263_2	706587.Desti_2759	5.746e-153	508.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MS08@213462|Syntrophobacterales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
GZD2_k127_6216263_0	926569.ANT_08410	1.334e-212	670.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GZD2_k127_6216263_1	926569.ANT_08420	4.965e-155	503.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GZD2_k127_6216263_9	1122919.KB905555_gene984	1.039e-54	200.0	COG2890@1|root,COG2890@2|Bacteria,1V4FF@1239|Firmicutes,4HHHN@91061|Bacilli,26XJ6@186822|Paenibacillaceae	91061|Bacilli	J	RRNA methyltransferase AviRa	-	-	2.1.1.209	ko:K21515	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	AviRa
GZD2_k127_6216263_11	710421.Mycch_2983	6.228e-51	183.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria,239IG@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_6216263_12	1128421.JAGA01000003_gene3335	2.391e-44	164.0	COG2207@1|root,COG2207@2|Bacteria,2NS1E@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	araC	-	-	ko:K21701	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding_2,HTH_18
GZD2_k127_6216263_8	1005048.CFU_3526	1.22e-60	215.0	COG2267@1|root,COG2267@2|Bacteria,1MZRF@1224|Proteobacteria,2VTRG@28216|Betaproteobacteria	28216|Betaproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD2_k127_6216263_16	1267534.KB906754_gene3295	3.431e-24	104.0	2FCYS@1|root,3451F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6216263_17	2423.NA23_0201945	1.479e-20	98.0	2ERRQ@1|root,33JAW@2|Bacteria,2GEA1@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6216263_5	1267211.KI669560_gene1993	1.276e-116	386.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GZD2_k127_6216263_10	765420.OSCT_0159	1.145e-54	199.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,377EF@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
GZD2_k127_6216263_3	1379698.RBG1_1C00001G1677	4.378e-126	411.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GZD2_k127_6216263_18	867845.KI911784_gene2110	4.754e-09	62.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
GZD2_k127_6216263_13	383372.Rcas_2747	2.525e-39	152.0	COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,2G5J9@200795|Chloroflexi,377YG@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_622004_4	744872.Spica_2539	6.464e-24	113.0	COG4166@1|root,COG4166@2|Bacteria,2J687@203691|Spirochaetes	203691|Spirochaetes	E	extracellular solute-binding protein, family 5	oppA-1	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD2_k127_622004_3	935261.JAGL01000031_gene307	5.593e-34	141.0	COG1802@1|root,COG1802@2|Bacteria,1N7NH@1224|Proteobacteria,2UE2P@28211|Alphaproteobacteria,43HTJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD2_k127_622004_0	1449126.JQKL01000004_gene567	7.533e-95	322.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268KP@186813|unclassified Clostridiales	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
GZD2_k127_622004_2	1009370.ALO_00310	8.574e-84	289.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H1VB@909932|Negativicutes	909932|Negativicutes	EP	Permease	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
GZD2_k127_622004_5	345341.KUTG_01977	2.872e-23	109.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4EE2D@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD2_k127_622004_1	316274.Haur_3591	1.756e-87	298.0	COG4948@1|root,COG4948@2|Bacteria,2G882@200795|Chloroflexi,3757P@32061|Chloroflexia	2|Bacteria	M	mandelate racemase muconate lactonizing	ycjG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620	MR_MLE_C,MR_MLE_N
GZD2_k127_6221224_0	926569.ANT_13310	8.365e-96	328.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
GZD2_k127_6221224_2	251229.Chro_4274	8.214e-59	218.0	COG2133@1|root,COG2133@2|Bacteria,1G06W@1117|Cyanobacteria,3VJXP@52604|Pleurocapsales	1117|Cyanobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GZD2_k127_6221224_1	926560.KE387027_gene263	4.958e-84	287.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GZD2_k127_6221224_3	926569.ANT_25330	4.53e-33	134.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD2_k127_6224910_1	926569.ANT_06470	1.31e-131	425.0	COG2089@1|root,COG2089@2|Bacteria,2G8IV@200795|Chloroflexi	200795|Chloroflexi	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
GZD2_k127_6224910_0	926569.ANT_06460	1.792e-152	491.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	-	2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
GZD2_k127_6224910_2	926569.ANT_06450	1.73e-57	201.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GZD2_k127_6236178_2	266117.Rxyl_3105	5.584e-15	83.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_3105|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6236178_1	1196322.A370_03213	9.143e-30	123.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,36KXB@31979|Clostridiaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD2_k127_6236178_0	926569.ANT_06410	5.478e-167	536.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
GZD2_k127_6250359_4	316274.Haur_3323	2.447e-31	126.0	COG1051@1|root,COG1694@1|root,COG1051@2|Bacteria,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia	32061|Chloroflexia	F	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
GZD2_k127_6250359_2	926569.ANT_14050	8.794e-54	194.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GZD2_k127_6250359_0	926569.ANT_10600	1.453e-244	762.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GZD2_k127_6250359_7	497964.CfE428DRAFT_3727	2.963e-13	77.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
GZD2_k127_6250359_6	497964.CfE428DRAFT_3727	8.787e-23	106.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
GZD2_k127_6250359_1	204669.Acid345_3113	2.254e-149	484.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GZD2_k127_6250359_3	1385521.N803_05460	1.4e-36	143.0	2EMAT@1|root,33EZU@2|Bacteria,2HMP6@201174|Actinobacteria,4FHFN@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6258369_3	926569.ANT_10550	1.576e-45	167.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD2_k127_6258369_1	485913.Krac_0932	1.526e-62	220.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_6258369_4	457412.RSAG_03419	1.891e-27	122.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD2_k127_6258369_2	926560.KE387023_gene1251	2.289e-58	207.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GZD2_k127_6258369_0	926569.ANT_03400	1.509e-106	359.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_6258369_6	1122138.AQUZ01000040_gene6209	1.267e-08	61.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_6265025_7	926569.ANT_12420	1.599e-15	77.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
GZD2_k127_6265025_2	926569.ANT_12410	2.852e-126	413.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi	200795|Chloroflexi	HJ	Belongs to the RimK family	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
GZD2_k127_6265025_0	926569.ANT_12400	1.84e-152	488.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GZD2_k127_6265025_5	383372.Rcas_3466	3.805e-93	314.0	COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,375DI@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GZD2_k127_6265025_1	316274.Haur_3309	4.307e-141	460.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi,375D1@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD2_k127_6265025_3	926569.ANT_12370	1.167e-103	347.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
GZD2_k127_6265025_6	926550.CLDAP_29780	1.008e-68	248.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD2_k127_6265025_4	926550.CLDAP_29790	3.08e-93	319.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD2_k127_6275904_0	163908.KB235896_gene4899	1.062e-164	535.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HR5M@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
GZD2_k127_6275904_1	926569.ANT_20350	7.866e-141	460.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_6275904_2	1128421.JAGA01000002_gene746	1.635e-100	341.0	COG0438@1|root,COG0438@2|Bacteria,2NRC9@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	pslH	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GZD2_k127_6275904_3	324602.Caur_3763	6.927e-60	216.0	COG1216@1|root,COG1216@2|Bacteria,2G7UG@200795|Chloroflexi,3764Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GZD2_k127_6285561_1	404589.Anae109_0590	9.263e-62	219.0	COG0702@1|root,COG0702@2|Bacteria,1PFUF@1224|Proteobacteria,42R6E@68525|delta/epsilon subdivisions,2WN7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GZD2_k127_6285561_3	1121104.AQXH01000001_gene1984	1.256e-18	92.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1ISGU@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
GZD2_k127_6285561_0	926569.ANT_18180	4.878e-128	423.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD2_k127_6285561_2	215803.DB30_5784	4.316e-19	90.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,42RE9@68525|delta/epsilon subdivisions,2WNSX@28221|Deltaproteobacteria,2YU8K@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
GZD2_k127_6288361_3	1380390.JIAT01000009_gene1821	3.235e-20	95.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
GZD2_k127_6288361_1	330214.NIDE3889	7.717e-72	248.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
GZD2_k127_6288361_2	234267.Acid_6209	1.681e-26	115.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GZD2_k127_6288361_4	867903.ThesuDRAFT_00391	3.676e-12	71.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GZD2_k127_6288361_5	362242.MUL_1368	1.654e-05	53.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,2350H@1762|Mycobacteriaceae	201174|Actinobacteria	C	succinate dehydrogenase	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GZD2_k127_6288361_0	926569.ANT_22150	1.564e-286	889.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GZD2_k127_6289587_4	1121918.ARWE01000001_gene3370	1.059e-23	106.0	COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria	1224|Proteobacteria	P	iron permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
GZD2_k127_6289587_3	751945.Theos_2091	5.882e-52	193.0	COG0321@1|root,COG0321@2|Bacteria,1WIJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GZD2_k127_6289587_1	886293.Sinac_3058	2.072e-137	451.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
GZD2_k127_6289587_0	1303518.CCALI_01587	9.548e-144	471.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GZD2_k127_6289587_2	1192034.CAP_3530	2.01e-58	212.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
GZD2_k127_6291108_6	1089455.MOPEL_003_01150	3.717e-59	223.0	COG0437@1|root,COG0437@2|Bacteria,2HGMU@201174|Actinobacteria,4F7JN@85018|Dermatophilaceae	201174|Actinobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
GZD2_k127_6291108_0	484770.UFO1_2838	1.927e-241	769.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD2_k127_6291108_5	1382306.JNIM01000001_gene4037	3.387e-66	239.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GZD2_k127_6291108_1	383372.Rcas_3557	2.419e-212	672.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD2_k127_6291108_11	1261545.MBE-HAL_0876	3.607e-25	112.0	COG1845@1|root,arCOG04650@2157|Archaea,2XTFU@28890|Euryarchaeota,23SSB@183963|Halobacteria	183963|Halobacteria	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GZD2_k127_6291108_8	357808.RoseRS_2267	1.337e-52	194.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi,3779Z@32061|Chloroflexia	32061|Chloroflexia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GZD2_k127_6291108_13	1267533.KB906738_gene2420	0.0008316	44.0	2C2MA@1|root,2Z87X@2|Bacteria,3Y4B4@57723|Acidobacteria,2JIC2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6291108_10	1455608.JDTH01000006_gene2516	1.427e-31	132.0	COG0843@1|root,arCOG01237@2157|Archaea,2XTBK@28890|Euryarchaeota,23S4J@183963|Halobacteria	183963|Halobacteria	C	Belongs to the heme-copper respiratory oxidase family	coxA2	-	1.9.3.1	ko:K15408	ko00190,map00190	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX1,COX3
GZD2_k127_6291108_12	1041139.KB902635_gene3849	2.763e-16	88.0	COG4454@1|root,COG4454@2|Bacteria,1PC23@1224|Proteobacteria,2V3KV@28211|Alphaproteobacteria,4BJ4Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6291108_9	383372.Rcas_2982	1.03e-38	151.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GZD2_k127_6291108_2	926569.ANT_08960	2.549e-121	401.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G8NY@200795|Chloroflexi	200795|Chloroflexi	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
GZD2_k127_6291108_3	1293054.HSACCH_00979	7.445e-114	383.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,249WU@186801|Clostridia,3WB1M@53433|Halanaerobiales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GZD2_k127_6291108_4	1293054.HSACCH_00980	4.223e-86	294.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WBQ6@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_6291108_7	1293054.HSACCH_00981	1.917e-53	201.0	COG0395@1|root,COG0395@2|Bacteria,1V3Y9@1239|Firmicutes,25C5H@186801|Clostridia,3WBP0@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD2_k127_6293478_4	1111479.AXAR01000001_gene132	1.137e-21	96.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,4HD7F@91061|Bacilli,2794M@186823|Alicyclobacillaceae	91061|Bacilli	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GZD2_k127_6293478_3	926569.ANT_04160	5.478e-23	103.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
GZD2_k127_6293478_0	926569.ANT_04150	1.596e-60	221.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_6293478_1	1536772.R70723_05780	1.878e-24	108.0	2EFA7@1|root,33935@2|Bacteria,1VJ00@1239|Firmicutes,4I89B@91061|Bacilli,26ZBC@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6293478_5	1304284.L21TH_2323	8.044e-06	52.0	29UMQ@1|root,30FZ8@2|Bacteria,1UEX1@1239|Firmicutes,25P4R@186801|Clostridia,36TYD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6299776_5	521097.Coch_0115	4.768e-19	90.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HY1P@117743|Flavobacteriia,1EQV5@1016|Capnocytophaga	976|Bacteroidetes	V	abc transporter (atp-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_6299776_4	309807.SRU_0474	1.839e-36	142.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_6299776_3	765420.OSCT_0043	9.421e-47	186.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
GZD2_k127_6299776_0	926550.CLDAP_07720	5.208e-115	382.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GZD2_k127_6299776_2	926550.CLDAP_07730	1.935e-47	177.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_10010	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD2_k127_6299776_1	316274.Haur_3936	8.09e-107	357.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi,3780K@32061|Chloroflexia	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD2_k127_6308888_1	479434.Sthe_1703	3.481e-131	435.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi,27XIK@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
GZD2_k127_6308888_3	926569.ANT_20990	3.36e-93	312.0	COG1940@1|root,COG1940@2|Bacteria,2G7NH@200795|Chloroflexi	200795|Chloroflexi	GK	ROK family	ppgK	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD2_k127_6308888_4	525904.Tter_2199	2.452e-90	304.0	COG2227@1|root,COG2227@2|Bacteria,2NRF7@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
GZD2_k127_6308888_7	1521187.JPIM01000045_gene1439	1.394e-72	267.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GZD2_k127_6308888_0	644282.Deba_0431	3.512e-171	554.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
GZD2_k127_6308888_8	1386089.N865_05205	4.395e-65	229.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria,4FJWG@85021|Intrasporangiaceae	201174|Actinobacteria	S	NADP oxidoreductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GZD2_k127_6308888_9	926560.KE387025_gene4131	3.813e-60	219.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_6308888_11	452637.Oter_4180	1.502e-46	172.0	COG5478@1|root,COG5478@2|Bacteria,46SXC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
GZD2_k127_6308888_12	1089550.ATTH01000001_gene1187	1.137e-29	123.0	COG3339@1|root,COG3339@2|Bacteria,4NRQP@976|Bacteroidetes,1FK9F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
GZD2_k127_6308888_2	1379698.RBG1_1C00001G1677	1.63e-127	417.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GZD2_k127_6308888_5	485913.Krac_1674	8.188e-80	277.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD2_k127_6308888_6	756499.Desde_2058	2.218e-73	255.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
GZD2_k127_6308888_10	1033810.HLPCO_000770	1.053e-47	177.0	COG0405@1|root,COG0405@2|Bacteria,2NQK8@2323|unclassified Bacteria	2|Bacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GZD2_k127_6308998_4	324602.Caur_0298	1.687e-24	121.0	COG0823@1|root,COG3210@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6308998_7	67352.JODS01000055_gene2241	2.942e-05	57.0	COG1404@1|root,COG2247@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,2IATQ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6308998_6	247490.KSU1_C0653	3.652e-06	51.0	COG3237@1|root,COG3237@2|Bacteria,2J0JU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
GZD2_k127_6308998_1	880073.Calab_3430	6.565e-91	308.0	COG1313@1|root,COG1313@2|Bacteria,2NP6I@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
GZD2_k127_6308998_0	926569.ANT_19790	2.901e-201	653.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GZD2_k127_6308998_5	907348.TresaDRAFT_0998	3.703e-19	96.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Hexapep,Methyltransf_21,V_cholerae_RfbT
GZD2_k127_6308998_2	864702.OsccyDRAFT_1593	5.688e-80	276.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_6308998_3	864702.OsccyDRAFT_1594	3.96e-40	157.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_2,TPR_8
GZD2_k127_6311686_1	266117.Rxyl_2946	3.03e-93	332.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GZD2_k127_6311686_0	237368.SCABRO_01423	7.609e-143	459.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GZD2_k127_6317562_0	649638.Trad_1728	6.835e-203	646.0	COG1874@1|root,COG1874@2|Bacteria,1WJAT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
GZD2_k127_6317562_1	1094508.Tsac_2301	2.296e-104	350.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,248Q3@186801|Clostridia	186801|Clostridia	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GZD2_k127_6317562_2	1196322.A370_03332	1.145e-33	141.0	COG5297@1|root,COG5297@2|Bacteria,1UZ72@1239|Firmicutes,25DAV@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 66	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Glyco_hydro_66
GZD2_k127_6320803_0	1128421.JAGA01000002_gene1513	2.685e-97	330.0	COG0737@1|root,COG0737@2|Bacteria,2NQJ5@2323|unclassified Bacteria	2|Bacteria	F	5'-nucleotidase, C-terminal domain	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
GZD2_k127_6320803_1	3055.EDO96374	3.262e-55	205.0	28K1M@1|root,2QSG2@2759|Eukaryota,382J6@33090|Viridiplantae,34NRG@3041|Chlorophyta	3041|Chlorophyta	F	D-ala D-ala ligase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
GZD2_k127_6320803_2	926550.CLDAP_26730	5.731e-41	153.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GZD2_k127_6320803_3	926550.CLDAP_26730	1.146e-39	150.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GZD2_k127_6320803_4	646529.Desaci_0681	6.855e-11	69.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
GZD2_k127_6322925_0	1128421.JAGA01000002_gene1086	0.0	1045.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	yicI	GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
GZD2_k127_6322925_1	756499.Desde_1765	1.829e-167	537.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,2612Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
GZD2_k127_6322925_3	264732.Moth_1899	1.374e-81	285.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,42ETY@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_6322925_2	913865.DOT_4411	2.489e-82	287.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,261AQ@186807|Peptococcaceae	186801|Clostridia	U	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD2_k127_6322925_4	765420.OSCT_0041	5.261e-81	281.0	COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi,37725@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_6325770_0	1476876.JOJO01000012_gene4155	1.185e-98	329.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_6325770_1	1536773.R70331_17850	2.208e-36	149.0	COG0842@1|root,COG0842@2|Bacteria,1V0J8@1239|Firmicutes,4HEBH@91061|Bacilli,26U1I@186822|Paenibacillaceae	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD2_k127_6325770_2	1121946.AUAX01000031_gene987	1.346e-35	145.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria,4DCAY@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD2_k127_6326265_2	426114.THI_2293	2.549e-13	72.0	2D8TI@1|root,32TRX@2|Bacteria,1N5N2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6326265_1	84531.JMTZ01000024_gene4042	3.753e-59	209.0	COG1670@1|root,COG1670@2|Bacteria,1N18Y@1224|Proteobacteria,1S8ZQ@1236|Gammaproteobacteria,1X6VH@135614|Xanthomonadales	135614|Xanthomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_6326265_0	471854.Dfer_5273	4.287e-83	285.0	COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,47MWM@768503|Cytophagia	976|Bacteroidetes	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GZD2_k127_6358783_4	1122221.JHVI01000020_gene1064	6.443e-45	167.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	phnO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Condensation
GZD2_k127_6358783_7	123899.JPQP01000004_gene675	8.47e-17	84.0	COG1250@1|root,COG2388@1|root,COG1250@2|Bacteria,COG2388@2|Bacteria,1MV8M@1224|Proteobacteria,2VJ64@28216|Betaproteobacteria,3T24A@506|Alcaligenaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
GZD2_k127_6358783_3	1341151.ASZU01000004_gene129	4.749e-52	194.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27BEX@186824|Thermoactinomycetaceae	91061|Bacilli	S	Dihydroxyacetone kinase family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_6358783_1	926569.ANT_25010	1.321e-244	760.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
GZD2_k127_6358783_8	164328.Phyra72693	0.0001206	52.0	KOG4351@1|root,KOG4351@2759|Eukaryota,3Q8PI@4776|Peronosporales	4776|Peronosporales	S	Ig-like domain from next to BRCA1 gene	-	-	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1
GZD2_k127_6358783_0	926569.ANT_24980	3.908e-307	964.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GZD2_k127_6358783_5	866536.Belba_1794	2.018e-29	123.0	2E14Q@1|root,32WJU@2|Bacteria,4PP5R@976|Bacteroidetes	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_6358783_2	1382306.JNIM01000001_gene3886	1.194e-104	350.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GZD2_k127_636814_1	926569.ANT_11910	7.028e-82	282.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD2_k127_636814_0	926569.ANT_11930	2.992e-158	508.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GZD2_k127_636814_2	867845.KI911784_gene2000	3.353e-35	139.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	wzb	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GZD2_k127_636814_3	1499967.BAYZ01000089_gene5038	3.325e-25	110.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GZD2_k127_6377105_0	926569.ANT_28720	6.294e-115	373.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_6377105_2	452637.Oter_0576	2.118e-53	199.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
GZD2_k127_6377105_1	926569.ANT_23610	7.168e-75	259.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GZD2_k127_6379198_0	926569.ANT_10480	6.498e-127	418.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GZD2_k127_6379198_1	926569.ANT_10520	1.044e-86	297.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GZD2_k127_6379198_3	926569.ANT_10530	7.968e-32	125.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GZD2_k127_6379198_2	926569.ANT_10540	4.473e-77	265.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GZD2_k127_6379198_4	268407.PWYN_01555	8.891e-20	93.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,271ZH@186822|Paenibacillaceae	91061|Bacilli	M	Mur ligase family, catalytic domain	-	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD2_k127_6402761_2	485918.Cpin_5041	3.013e-26	109.0	COG0859@1|root,COG0859@2|Bacteria,4NI4Y@976|Bacteroidetes,1IQNQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GZD2_k127_6402761_0	479434.Sthe_3174	1.39e-147	476.0	COG0535@1|root,COG0535@2|Bacteria,2G75Y@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
GZD2_k127_6402761_1	1169143.KB911038_gene6075	1.515e-95	325.0	COG1215@1|root,COG1215@2|Bacteria,1QTZ1@1224|Proteobacteria,2VWJU@28216|Betaproteobacteria,1K0FJ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_6402761_3	977880.RALTA_A0588	2.376e-24	102.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,1K410@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
GZD2_k127_6404994_1	631362.Thi970DRAFT_02821	1.056e-82	284.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QR54@1224|Proteobacteria,1SMRM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_6404994_3	926569.ANT_15290	3.554e-56	200.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6404994_2	926569.ANT_15280	7.836e-70	240.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GZD2_k127_6404994_0	926569.ANT_15270	1.582e-289	911.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GZD2_k127_6404994_6	1380356.JNIK01000001_gene2209	2.454e-43	169.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4ESRV@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
GZD2_k127_6404994_7	574087.Acear_1046	3.784e-24	109.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WAQW@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
GZD2_k127_6404994_5	1128421.JAGA01000002_gene530	1.873e-46	191.0	28J8U@1|root,33EE0@2|Bacteria	2|Bacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
GZD2_k127_6404994_4	926550.CLDAP_35170	3.277e-47	174.0	COG0346@1|root,COG0346@2|Bacteria,2G9TR@200795|Chloroflexi	200795|Chloroflexi	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
GZD2_k127_6408932_1	1196322.A370_03332	4.912e-76	270.0	COG5297@1|root,COG5297@2|Bacteria,1UZ72@1239|Firmicutes,25DAV@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 66	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Glyco_hydro_66
GZD2_k127_6408932_0	1203556.HMPREF1478_01051	1.779e-78	270.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D60B@85005|Actinomycetales	201174|Actinobacteria	P	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GZD2_k127_64283_3	1128421.JAGA01000003_gene3270	2.85e-29	122.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_64283_0	1111479.AXAR01000006_gene808	6.671e-110	376.0	COG0531@1|root,COG0531@2|Bacteria,1UXZ2@1239|Firmicutes,4HDT0@91061|Bacilli	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD2_k127_64283_2	1203605.HMPREF1531_00752	6.098e-30	122.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria,4DVTC@85009|Propionibacteriales	201174|Actinobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
GZD2_k127_64283_1	926569.ANT_07180	4.698e-68	236.0	COG4819@1|root,COG4819@2|Bacteria	2|Bacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
GZD2_k127_6452098_0	449447.MAE_11540	7.122e-148	484.0	COG1413@1|root,COG1413@2|Bacteria,1G2TK@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6452098_2	449447.MAE_11550	4.55e-46	182.0	COG4675@1|root,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria	1117|Cyanobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
GZD2_k127_6452098_1	449447.MAE_11600	5.095e-72	271.0	2DB7G@1|root,2Z7M5@2|Bacteria,1G3PP@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6452673_3	926569.ANT_03650	2.064e-28	117.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
GZD2_k127_6452673_5	234267.Acid_2155	1.603e-06	56.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD2_k127_6452673_2	1227360.C176_07437	1.106e-30	129.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26E4T@186818|Planococcaceae	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
GZD2_k127_6452673_4	926569.ANT_29790	3.578e-23	101.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GZD2_k127_6452673_1	926569.ANT_29790	9.999e-40	151.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
GZD2_k127_6452673_0	235985.BBPN01000077_gene7066	8.872e-180	577.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria,2NKAJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6462311_7	926569.ANT_13840	1.485e-42	166.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_6462311_9	1521187.JPIM01000171_gene3728	1.211e-32	136.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
GZD2_k127_6462311_10	1128421.JAGA01000003_gene3050	2.805e-10	68.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
GZD2_k127_6462311_3	1449126.JQKL01000016_gene2859	4.364e-79	272.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
GZD2_k127_6462311_8	309801.trd_A0141	2.223e-34	142.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GZD2_k127_6462311_0	926569.ANT_25660	0.0	1190.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Big_5,MG1
GZD2_k127_6462311_6	926569.ANT_30170	1.604e-46	177.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
GZD2_k127_6462311_4	926569.ANT_30180	5.22e-73	251.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
GZD2_k127_6462311_2	459349.CLOAM1351	7.051e-81	283.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
GZD2_k127_6462311_1	926569.ANT_15920	1.74e-95	319.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GZD2_k127_6462311_5	926569.ANT_15930	3.791e-49	179.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GZD2_k127_6470038_1	485913.Krac_2105	4.222e-76	262.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD2_k127_6470038_0	926569.ANT_01260	5.09e-143	459.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GZD2_k127_64768_0	926550.CLDAP_35040	3.188e-80	275.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2G6GF@200795|Chloroflexi	200795|Chloroflexi	K	Low molecular weight phosphotyrosine protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,LMWPc
GZD2_k127_64768_2	926549.KI421517_gene616	2.681e-68	239.0	COG0639@1|root,COG0639@2|Bacteria,4NFPU@976|Bacteroidetes,47MX3@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD2_k127_64768_3	913865.DOT_1129	1.066e-07	53.0	COG0639@1|root,COG0639@2|Bacteria,1UYWK@1239|Firmicutes,25DVG@186801|Clostridia,2603Q@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM phosphodiesterase, MJ0936	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD2_k127_64768_1	926550.CLDAP_40590	5.567e-72	251.0	COG0535@1|root,COG2002@1|root,COG0535@2|Bacteria,COG2002@2|Bacteria,2G75Y@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
GZD2_k127_6487938_7	1521187.JPIM01000129_gene3618	5.086e-11	69.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
GZD2_k127_6487938_0	926569.ANT_01340	2.478e-149	489.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GZD2_k127_6487938_4	926569.ANT_01350	2.358e-37	143.0	COG0718@1|root,COG0718@2|Bacteria	2|Bacteria	S	YbaB/EbfC DNA-binding family	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K06187,ko:K09747	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	YbaB_DNA_bd
GZD2_k127_6487938_5	485913.Krac_10510	2.899e-17	87.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
GZD2_k127_6487938_1	926569.ANT_01360	2.213e-85	287.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
GZD2_k127_6487938_2	298653.Franean1_5217	3.6e-83	291.0	COG2110@1|root,COG2110@2|Bacteria,2IBAB@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
GZD2_k127_6487938_3	485913.Krac_3036	6.409e-56	203.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudK	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0052751	3.6.1.13	ko:K01515,ko:K12945	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_1537,iNRG857_1313.NRG857_12310,iUTI89_1310.UTI89_C2793,ic_1306.c2994	NUDIX
GZD2_k127_6487938_8	3988.XP_002512608.1	5.898e-07	53.0	KOG1192@1|root,KOG1192@2759|Eukaryota,37Q15@33090|Viridiplantae,3GHI8@35493|Streptophyta,4JS7M@91835|fabids	35493|Streptophyta	CG	Sterol 3-beta-glucosyltransferase UGT80A2-like	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008194,GO:0016740,GO:0016757,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
GZD2_k127_6487938_9	441769.ABFU01000135_gene3474	1.919e-06	51.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes,4I01W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6494411_3	1117318.PRUB_11011	1.9e-20	100.0	2DNRZ@1|root,32YVF@2|Bacteria,1NAFT@1224|Proteobacteria,1SD5G@1236|Gammaproteobacteria,2Q3PP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
GZD2_k127_6494411_1	304371.MCP_0932	5.621e-61	215.0	arCOG12320@1|root,arCOG12320@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6494411_5	632335.Calkr_0077	1.59e-11	68.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42G18@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
GZD2_k127_6494411_2	926569.ANT_18300	2.521e-29	121.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GZD2_k127_6494411_0	926569.ANT_18310	2.132e-213	672.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD2_k127_6504590_11	926569.ANT_10650	1.096e-45	172.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TPMT
GZD2_k127_6504590_9	1183438.GKIL_4241	7.081e-55	202.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GZD2_k127_6504590_4	1382359.JIAL01000001_gene1651	2.353e-122	399.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JHSA@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase (Decarboxylating)	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GZD2_k127_6504590_1	530564.Psta_2488	1.165e-156	507.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GZD2_k127_6504590_12	555079.Toce_0773	4.067e-35	141.0	COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GEY@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
GZD2_k127_6504590_13	63737.Npun_R1174	1.077e-12	74.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1HNCP@1161|Nostocales	1117|Cyanobacteria	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD2_k127_6504590_7	357808.RoseRS_3747	4.91e-90	300.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_6504590_14	357808.RoseRS_2658	1.962e-09	70.0	COG1807@1|root,COG3118@1|root,COG1807@2|Bacteria,COG3118@2|Bacteria,2GA9N@200795|Chloroflexi,374X1@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD2_k127_6504590_10	582899.Hden_0828	1.537e-54	200.0	COG2940@1|root,COG2940@2|Bacteria,1NEA4@1224|Proteobacteria,2VGQI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
GZD2_k127_6504590_6	926550.CLDAP_19350	1.911e-116	380.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	iEC55989_1330.EC55989_1575,iECIAI1_1343.ECIAI1_1439,iECO111_1330.ECO111_1832,iECO26_1355.ECO26_2042,iECW_1372.ECW_m1571,iECs_1301.ECs2047,iEKO11_1354.EKO11_2376,iUMNK88_1353.UMNK88_1846,iWFL_1372.ECW_m1571,iZ_1308.Z2276,ic_1306.c1867	BPD_transp_1
GZD2_k127_6504590_5	395961.Cyan7425_3620	3.916e-118	388.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,3KIME@43988|Cyanothece	1117|Cyanobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
GZD2_k127_6504590_2	926550.CLDAP_19330	1.135e-141	458.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	ydcT	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
GZD2_k127_6504590_0	717785.HYPMC_3797	5.818e-184	584.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,2TYST@28211|Alphaproteobacteria,3N981@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_8
GZD2_k127_6504590_8	525904.Tter_0351	3.831e-62	224.0	COG2362@1|root,COG2362@2|Bacteria,2NPDW@2323|unclassified Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GZD2_k127_6504590_16	266117.Rxyl_0497	7.085e-06	55.0	COG3296@1|root,COG3296@2|Bacteria,2GXDT@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
GZD2_k127_6504590_3	406124.ACPC01000022_gene4081	4.842e-131	429.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD2_k127_6504590_15	1128421.JAGA01000003_gene3091	3.083e-07	62.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
GZD2_k127_6507307_1	485913.Krac_5583	2.132e-97	326.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GZD2_k127_6507307_0	357808.RoseRS_3371	8.579e-131	447.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,Response_reg
GZD2_k127_6507307_2	386456.JQKN01000007_gene3197	2.743e-42	178.0	arCOG03567@1|root,arCOG03567@2157|Archaea	2157|Archaea	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
GZD2_k127_6507307_3	318161.Sden_0892	0.0004874	46.0	COG1266@1|root,COG1266@2|Bacteria,1MWXT@1224|Proteobacteria,1S05B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD2_k127_6507967_5	926569.ANT_02040	2.574e-09	58.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
GZD2_k127_6507967_6	2903.EOD17999	0.0003797	46.0	COG0526@1|root,KOG0907@2759|Eukaryota	2759|Eukaryota	CO	cell redox homeostasis	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009636,GO:0009987,GO:0010190,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0017004,GO:0019725,GO:0022607,GO:0031976,GO:0031977,GO:0031984,GO:0033554,GO:0034357,GO:0034599,GO:0034622,GO:0042221,GO:0042592,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055035,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070887,GO:0071840,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD2_k127_6507967_1	485913.Krac_2372	3.463e-99	337.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_6507967_0	926569.ANT_15620	1.48e-196	626.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GZD2_k127_6507967_3	1382306.JNIM01000001_gene3987	1.827e-29	132.0	COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi	200795|Chloroflexi	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
GZD2_k127_6507967_2	926569.ANT_15640	5.053e-64	229.0	COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
GZD2_k127_6507967_4	1223410.KN050846_gene566	1.633e-11	76.0	COG2815@1|root,COG2815@2|Bacteria,4NXFG@976|Bacteroidetes,1I6HM@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	TIR_2
GZD2_k127_651132_1	926569.ANT_02740	1.57e-27	112.0	COG0234@1|root,COG0234@2|Bacteria,2G79Y@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
GZD2_k127_651132_0	525904.Tter_0222	3.42e-132	434.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
GZD2_k127_651132_2	521045.Kole_0436	1.517e-10	67.0	2DUHG@1|root,33QNU@2|Bacteria,2GDRM@200918|Thermotogae	200918|Thermotogae	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GZD2_k127_6526626_1	1329516.JPST01000075_gene1931	7.453e-89	299.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,27AU9@186824|Thermoactinomycetaceae	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD2_k127_6526626_4	504487.JCM19302_4250	4.473e-12	75.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia	976|Bacteroidetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD2_k127_6526626_3	316274.Haur_2729	2.111e-22	113.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD2_k127_6526626_0	880071.Fleli_0094	5.393e-218	698.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
GZD2_k127_6526626_2	639282.DEFDS_0814	1.247e-39	149.0	COG0372@1|root,COG0372@2|Bacteria,2GEZB@200930|Deferribacteres	200930|Deferribacteres	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GZD2_k127_6542402_1	926569.ANT_06450	6.399e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GZD2_k127_6542402_4	13689.BV96_02858	2.323e-15	89.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
GZD2_k127_6542402_0	867845.KI911784_gene1213	6.084e-261	814.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
GZD2_k127_6542402_2	903818.KI912268_gene1808	5.785e-60	226.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT_2
GZD2_k127_6548545_0	926569.ANT_15930	6.075e-111	365.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GZD2_k127_6548545_1	926569.ANT_15940	9.764e-82	282.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GZD2_k127_6551311_6	192952.MM_2103	7.695e-26	109.0	COG0500@1|root,arCOG07825@2157|Archaea	2157|Archaea	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD2_k127_6551311_5	765420.OSCT_0713	2.965e-29	128.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_6551311_4	326427.Cagg_2374	1.796e-41	166.0	COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD2_k127_6551311_2	237368.SCABRO_01358	8.856e-107	354.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GZD2_k127_6551311_1	118173.KB235914_gene3925	2.358e-126	422.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
GZD2_k127_6551311_0	1123248.KB893314_gene3524	2.668e-148	488.0	COG0463@1|root,COG0500@1|root,COG0463@2|Bacteria,COG2226@2|Bacteria,4PN6F@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD2_k127_6551311_3	670292.JH26_05170	5.96e-84	288.0	COG0463@1|root,COG0463@2|Bacteria,1RGMI@1224|Proteobacteria,2TYM6@28211|Alphaproteobacteria,1JVYX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_6551311_7	768671.ThimaDRAFT_3918	1.8e-13	78.0	2F10V@1|root,33U2E@2|Bacteria,1NUJB@1224|Proteobacteria,1SNRX@1236|Gammaproteobacteria,1X0M7@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_65729_3	1499967.BAYZ01000184_gene4564	7.175e-46	173.0	COG1564@1|root,COG1564@2|Bacteria,2NPUG@2323|unclassified Bacteria	2|Bacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
GZD2_k127_65729_1	926569.ANT_06700	1.033e-142	461.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi	200795|Chloroflexi	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
GZD2_k127_65729_0	926569.ANT_06710	4.292e-155	507.0	COG1178@1|root,COG1178@2|Bacteria,2G63A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
GZD2_k127_65729_2	926569.ANT_23590	4.4e-102	342.0	COG3842@1|root,COG3842@2|Bacteria,2G62Z@200795|Chloroflexi	200795|Chloroflexi	P	TOBE domain	-	-	3.6.3.31	ko:K02062,ko:K11072	ko02010,map02010	M00191,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
GZD2_k127_65729_4	926569.ANT_23580	9.292e-31	126.0	COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi	200795|Chloroflexi	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GZD2_k127_65729_5	1045855.DSC_11355	6.309e-18	88.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
GZD2_k127_669454_1	926569.ANT_12990	1.016e-121	400.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
GZD2_k127_669454_4	926569.ANT_18410	5.631e-46	174.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
GZD2_k127_669454_0	926569.ANT_18420	9.711e-129	442.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
GZD2_k127_669454_3	926569.ANT_14400	1.116e-85	290.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GZD2_k127_669454_2	926569.ANT_14410	9.976e-103	340.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM F420-dependent oxidoreductase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
GZD2_k127_669454_5	937777.Deipe_2763	4.916e-22	96.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
GZD2_k127_68052_2	429009.Adeg_2014	1.103e-42	160.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,42HGR@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
GZD2_k127_68052_0	1379698.RBG1_1C00001G0047	1.247e-221	696.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
GZD2_k127_68052_5	269799.Gmet_1532	3.282e-12	73.0	COG0664@1|root,COG0664@2|Bacteria,1PSVY@1224|Proteobacteria,42XY7@68525|delta/epsilon subdivisions,2WTBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GZD2_k127_68052_3	1449126.JQKL01000002_gene1553	5.853e-25	111.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
GZD2_k127_68052_4	1195236.CTER_3891	1.773e-13	74.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia,3WPWD@541000|Ruminococcaceae	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GZD2_k127_68052_1	926569.ANT_17860	2.172e-102	342.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GZD2_k127_681834_6	926550.CLDAP_35390	5.295e-12	67.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GZD2_k127_681834_2	926569.ANT_25160	8.252e-146	474.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GZD2_k127_681834_0	926569.ANT_25170	2.815e-170	544.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
GZD2_k127_681834_3	926569.ANT_25180	6.491e-39	155.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_681834_1	926569.ANT_25190	6.697e-149	482.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_681834_4	571.MC52_15565	1.104e-25	109.0	COG1943@1|root,COG1943@2|Bacteria,1RAP9@1224|Proteobacteria,1S230@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD2_k127_681834_7	329726.AM1_5416	0.0006317	43.0	COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD2_k127_681834_5	986075.CathTA2_1923	2.629e-19	88.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GZD2_k127_681963_4	926569.ANT_06330	7.985e-46	166.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD2_k127_681963_1	926569.ANT_06320	1.219e-160	522.0	COG0763@1|root,COG0763@2|Bacteria	2|Bacteria	M	lipid-A-disaccharide synthase activity	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	Capsule_synth
GZD2_k127_681963_0	926569.ANT_06310	1.555e-190	602.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
GZD2_k127_681963_3	234267.Acid_4640	1.029e-103	344.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
GZD2_k127_681963_2	926569.ANT_06290	1.065e-151	486.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GZD2_k127_681963_5	309807.SRU_0474	1.806e-41	156.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
GZD2_k127_681963_6	324602.Caur_2120	1.354e-15	77.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD2_k127_686831_2	1120971.AUCA01000023_gene534	7.74e-11	74.0	COG1566@1|root,COG1566@2|Bacteria,1TSAV@1239|Firmicutes,4HE0Q@91061|Bacilli,279BM@186823|Alicyclobacillaceae	91061|Bacilli	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
GZD2_k127_686831_1	2074.JNYD01000034_gene6445	2.399e-19	102.0	COG0845@1|root,COG0845@2|Bacteria,2IB2N@201174|Actinobacteria,4EEYJ@85010|Pseudonocardiales	201174|Actinobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
GZD2_k127_686831_3	1151117.AJLF01000002_gene233	0.0006473	47.0	COG2811@1|root,arCOG03363@2157|Archaea,2Y4VV@28890|Euryarchaeota,244QM@183968|Thermococci	183968|Thermococci	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
GZD2_k127_686831_0	1499967.BAYZ01000009_gene5285	6.142e-39	156.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
GZD2_k127_694494_0	926550.CLDAP_34110	1.197e-58	223.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GZD2_k127_700644_6	383372.Rcas_2157	3.086e-35	137.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,3766S@32061|Chloroflexia	32061|Chloroflexia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GZD2_k127_700644_1	1089553.Tph_c26530	6.05e-161	523.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GZD2_k127_700644_3	1336243.JAEA01000013_gene3290	2.729e-58	212.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,1JRHR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
GZD2_k127_700644_4	926569.ANT_05910	9.884e-57	204.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
GZD2_k127_700644_0	926569.ANT_05900	2.861e-187	592.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD2_k127_700644_2	926569.ANT_05890	1.308e-70	248.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GZD2_k127_700644_5	485913.Krac_5655	9.566e-36	139.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD2_k127_733822_1	1121946.AUAX01000004_gene928	6.002e-37	151.0	COG0454@1|root,COG0456@2|Bacteria,2HW3C@201174|Actinobacteria,4DI9Y@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_733822_0	99598.Cal7507_0942	2.444e-41	159.0	COG1670@1|root,COG1670@2|Bacteria,1GK85@1117|Cyanobacteria,1HTG0@1161|Nostocales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_733822_2	99598.Cal7507_0942	2.662e-33	137.0	COG1670@1|root,COG1670@2|Bacteria,1GK85@1117|Cyanobacteria,1HTG0@1161|Nostocales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_733822_3	1294265.JCM21738_3766	1.249e-32	134.0	COG1670@1|root,COG1670@2|Bacteria,1V3Q8@1239|Firmicutes,4HH72@91061|Bacilli,1ZQWD@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD2_k127_733822_4	1230343.CANP01000041_gene3088	4.061e-05	51.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,1JDGY@118969|Legionellales	118969|Legionellales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07661	ko02020,map02020	M00446	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_752547_3	886293.Sinac_4791	9.763e-22	111.0	COG5549@1|root,COG5549@2|Bacteria,2J0F7@203682|Planctomycetes	203682|Planctomycetes	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
GZD2_k127_752547_1	306281.AJLK01000061_gene5035	2.623e-76	259.0	COG1898@1|root,COG1898@2|Bacteria,1G0QA@1117|Cyanobacteria,1JK4P@1189|Stigonemataceae	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
GZD2_k127_752547_0	1392501.JIAC01000001_gene1347	1.118e-77	266.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4H40R@909932|Negativicutes	909932|Negativicutes	GM	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Wzt_C
GZD2_k127_752547_2	671143.DAMO_0907	2.031e-50	187.0	COG1682@1|root,COG1682@2|Bacteria,2NR4M@2323|unclassified Bacteria	2|Bacteria	GM	ABC-2 type transporter	rfbD	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
GZD2_k127_790950_6	227882.SAV_432	1.104e-25	109.0	COG3210@1|root,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria	201174|Actinobacteria	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
GZD2_k127_790950_0	926569.ANT_17590	0.0	1311.0	COG3459@1|root,COG3459@2|Bacteria,2G9NQ@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_790950_3	479434.Sthe_2989	3.2e-71	256.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD2_k127_790950_5	926569.ANT_16090	1.273e-60	215.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_790950_4	926569.ANT_16080	5.463e-71	255.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
GZD2_k127_790950_1	744872.Spica_0914	6.5e-80	274.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GZD2_k127_790950_2	742767.HMPREF9456_01660	3.91e-75	256.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GZD2_k127_794059_6	485913.Krac_1097	1.359e-35	140.0	2BWWR@1|root,2ZG0F@2|Bacteria	2|Bacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD2_k127_794059_5	929562.Emtol_2413	9.324e-38	146.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
GZD2_k127_794059_3	1227457.C451_15035	1.276e-44	171.0	COG0863@1|root,arCOG00115@2157|Archaea,2XXQ9@28890|Euryarchaeota,23VYI@183963|Halobacteria	183963|Halobacteria	L	COG0863 DNA modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
GZD2_k127_794059_7	768706.Desor_3591	3.682e-31	128.0	COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes	1239|Firmicutes	S	DinB family	dinB	-	-	-	-	-	-	-	-	-	-	-	DinB
GZD2_k127_794059_8	1128398.Curi_c20490	1.013e-19	96.0	COG1051@1|root,COG1051@2|Bacteria,1V58Q@1239|Firmicutes,25BM0@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD2_k127_794059_2	1499967.BAYZ01000055_gene4854	2.687e-74	255.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	yjhB	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	Acetyltransf_1,NUDIX,Nudix_N
GZD2_k127_794059_0	504728.K649_00930	4.13e-92	314.0	COG0167@1|root,COG0167@2|Bacteria,1WI2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GZD2_k127_794059_1	357808.RoseRS_2229	3.039e-80	293.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD2_k127_822970_4	1300345.LF41_2142	2.192e-09	58.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD2_k127_822970_1	439235.Dalk_2729	2.823e-42	162.0	COG3809@1|root,COG3809@2|Bacteria,1PZB0@1224|Proteobacteria,433GD@68525|delta/epsilon subdivisions,2WXX5@28221|Deltaproteobacteria,2MP8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
GZD2_k127_822970_2	485915.Dret_2352	8.44e-25	113.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
GZD2_k127_822970_0	484770.UFO1_4345	1.157e-137	449.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4H3UJ@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD2_k127_822970_3	1173027.Mic7113_0692	2.616e-15	78.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria,1HAWT@1150|Oscillatoriales	1117|Cyanobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
GZD2_k127_828823_3	1183438.GKIL_3646	3.564e-24	109.0	COG1215@1|root,COG1215@2|Bacteria,1G1FP@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GZD2_k127_828823_2	565575.UUR10_0611	8.047e-26	109.0	COG0050@1|root,COG0050@2|Bacteria,3WSWU@544448|Tenericutes	544448|Tenericutes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GZD2_k127_828823_0	383372.Rcas_2077	0.0	1017.0	COG0366@1|root,COG0366@2|Bacteria,2G7SV@200795|Chloroflexi	200795|Chloroflexi	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
GZD2_k127_828823_1	926569.ANT_15670	3.251e-59	229.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_830592_2	1337936.IJ00_26675	3.479e-58	210.0	COG1573@1|root,COG1573@2|Bacteria,1FZYH@1117|Cyanobacteria,1HID7@1161|Nostocales	1117|Cyanobacteria	L	TIGRFAM uracil-DNA glycosylase, family 4	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GZD2_k127_830592_1	926569.ANT_04070	2.098e-99	330.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
GZD2_k127_830592_0	926569.ANT_04060	2.364e-165	524.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GZD2_k127_836524_0	1329516.JPST01000012_gene192	0.0	1148.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,27BAB@186824|Thermoactinomycetaceae	91061|Bacilli	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GZD2_k127_836524_3	1499967.BAYZ01000141_gene6149	4.88e-07	63.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,GUN4,HTH_3,TIR_2
GZD2_k127_836524_1	1206741.BAFX01000043_gene3192	5.821e-23	104.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria,4G4WC@85025|Nocardiaceae	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
GZD2_k127_836524_2	1370121.AUWS01000030_gene2862	9.959e-12	67.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,23F1N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GZD2_k127_837732_3	926569.ANT_25690	5.062e-72	255.0	COG3287@1|root,COG3287@2|Bacteria,2G7G0@200795|Chloroflexi	200795|Chloroflexi	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
GZD2_k127_837732_5	1233950.IW22_17980	0.0008778	50.0	2DBYB@1|root,2ZBUC@2|Bacteria,4NRE9@976|Bacteroidetes,1I3UH@117743|Flavobacteriia,3ZR1V@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_837732_4	926569.ANT_12680	7.669e-34	135.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GZD2_k127_837732_0	357808.RoseRS_0174	5.696e-115	379.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
GZD2_k127_837732_2	357808.RoseRS_0170	1.147e-78	271.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
GZD2_k127_837732_1	357808.RoseRS_0169	4.96e-100	332.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
GZD2_k127_847144_2	290317.Cpha266_0841	2.628e-29	117.0	COG1132@1|root,COG1132@2|Bacteria,1FD6W@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_847144_0	926569.ANT_27190	3.83e-246	772.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	mdlB	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_847144_1	1191523.MROS_1501	5.351e-33	138.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
GZD2_k127_850281_3	580332.Slit_2983	2.95e-280	863.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,44V6D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GZD2_k127_850281_19	1485544.JQKP01000012_gene2165	2.889e-61	216.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,44VX0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GZD2_k127_850281_17	580332.Slit_2985	6.724e-69	236.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,44VTQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
GZD2_k127_850281_20	580332.Slit_2986	1.83e-35	136.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,44W3S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
GZD2_k127_850281_12	580332.Slit_2987	1.119e-117	384.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,44VW2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GZD2_k127_850281_25	1163617.SCD_n03027	0.0005459	48.0	2AFZM@1|root,3163K@2|Bacteria,1PWSR@1224|Proteobacteria,2VYPF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
GZD2_k127_850281_13	395494.Galf_2941	3.207e-107	355.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,44V9B@713636|Nitrosomonadales	28216|Betaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GZD2_k127_850281_9	580332.Slit_2990	2.686e-132	425.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,44VF0@713636|Nitrosomonadales	28216|Betaproteobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD2_k127_850281_15	1485544.JQKP01000012_gene2171	1.624e-93	310.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,44VPZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GZD2_k127_850281_23	395494.Galf_2944	1.273e-17	83.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GZD2_k127_850281_2	1485544.JQKP01000012_gene2172	6.149e-314	967.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GZD2_k127_850281_6	1485544.JQKP01000007_gene1999	1.623e-196	621.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,44V9H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
GZD2_k127_850281_4	395494.Galf_2946	3.503e-222	700.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,44V1I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
GZD2_k127_850281_21	580332.Slit_2995	7.22e-29	117.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,44W1S@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GZD2_k127_850281_24	1485544.JQKP01000007_gene1996	2.459e-16	83.0	COG0594@1|root,COG0594@2|Bacteria,1PXBW@1224|Proteobacteria,2WCTM@28216|Betaproteobacteria,44WN7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribonuclease P	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GZD2_k127_850281_22	580332.Slit_2997	6.205e-18	83.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GZD2_k127_850281_5	580332.Slit_0001	3.959e-213	670.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,44W93@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GZD2_k127_850281_7	580332.Slit_0002	9.39e-160	511.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,44W9E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GZD2_k127_850281_1	395494.Galf_0003	0.0	1258.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,44WB9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GZD2_k127_850281_0	1485544.JQKP01000002_gene1570	0.0	1334.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,44UZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
GZD2_k127_850281_18	580332.Slit_0005	1.186e-62	219.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,44VVY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF494)	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
GZD2_k127_850281_8	580332.Slit_0006	4.229e-150	482.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,44VI9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GZD2_k127_850281_10	580332.Slit_0007	2.533e-126	413.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,44VKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
GZD2_k127_850281_16	395494.Galf_0022	4.393e-73	249.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,44VPM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GZD2_k127_850281_11	580332.Slit_0009	2.169e-119	391.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,44V35@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
GZD2_k127_850281_14	1485544.JQKP01000002_gene1576	2.828e-99	330.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,44VEQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
GZD2_k127_852387_0	926550.CLDAP_36170	1.345e-187	592.0	COG1232@1|root,COG1232@2|Bacteria,2G83R@200795|Chloroflexi	200795|Chloroflexi	H	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD2_k127_852387_2	575540.Isop_3045	6.9e-53	193.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_852387_1	886293.Sinac_1691	9.417e-71	243.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_854030_2	926550.CLDAP_39970	3.445e-65	228.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
GZD2_k127_854030_1	247490.KSU1_D0632	1.08e-105	354.0	COG1275@1|root,COG1275@2|Bacteria,2J2HB@203682|Planctomycetes	203682|Planctomycetes	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
GZD2_k127_854030_3	323097.Nham_3445	3.255e-61	218.0	COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,2TTDB@28211|Alphaproteobacteria,3JWMR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
GZD2_k127_854030_4	323097.Nham_3446	2.92e-27	117.0	COG2180@1|root,COG2180@2|Bacteria,1NBVT@1224|Proteobacteria	1224|Proteobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
GZD2_k127_854030_0	1121918.ARWE01000001_gene3006	1.519e-116	381.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,42NWV@68525|delta/epsilon subdivisions,2WJWC@28221|Deltaproteobacteria,43TJN@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory nitrate reductase beta C-terminal	narH	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iAF987.Gmet_1021	Fer4_11,Nitr_red_bet_C
GZD2_k127_856506_7	316274.Haur_3847	1.63e-29	128.0	COG3186@1|root,COG3186@2|Bacteria,2GAHQ@200795|Chloroflexi,37677@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
GZD2_k127_856506_6	926569.ANT_20530	1.141e-44	171.0	COG0682@1|root,COG0682@2|Bacteria,2G8YW@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GZD2_k127_856506_4	765420.OSCT_1795	1.338e-50	185.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GZD2_k127_856506_5	118163.Ple7327_3995	3.669e-49	181.0	2C0PI@1|root,301XF@2|Bacteria,1GRAZ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_856506_3	1501230.ET33_02060	4.97e-51	200.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,26TF3@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
GZD2_k127_856506_1	926569.ANT_18080	2.621e-282	880.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GZD2_k127_856506_2	926569.ANT_18070	9.991e-54	192.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GZD2_k127_856506_0	926569.ANT_18060	1.499e-314	988.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GZD2_k127_856506_8	1148.1652554	4.346e-07	54.0	COG1826@1|root,COG1826@2|Bacteria,1G93D@1117|Cyanobacteria,1H60P@1142|Synechocystis	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GZD2_k127_856859_1	926569.ANT_30270	8.27e-157	503.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GZD2_k127_856859_2	926569.ANT_29410	3.231e-134	437.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GZD2_k127_856859_4	111780.Sta7437_2805	9.142e-19	90.0	COG0607@1|root,COG0607@2|Bacteria,1G7VW@1117|Cyanobacteria,3VK7T@52604|Pleurocapsales	1117|Cyanobacteria	P	PFAM Rhodanese-like domain	pspE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GZD2_k127_856859_0	926569.ANT_05040	2.289e-307	956.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GZD2_k127_856859_3	1265505.ATUG01000001_gene2914	1.477e-34	136.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2MJU9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
GZD2_k127_860281_5	886293.Sinac_4145	4.004e-11	75.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_8,WD40
GZD2_k127_860281_0	1128421.JAGA01000002_gene1693	5.329e-116	382.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_860281_3	1382306.JNIM01000001_gene1764	5.537e-42	164.0	COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_860281_2	1120973.AQXL01000097_gene911	1.033e-43	169.0	COG3694@1|root,COG3694@2|Bacteria,1UZ6K@1239|Firmicutes,4HCYU@91061|Bacilli,278UJ@186823|Alicyclobacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD2_k127_860281_4	720555.BATR1942_14640	3.226e-23	105.0	COG0346@1|root,COG0346@2|Bacteria,1VHBF@1239|Firmicutes,4HQQ0@91061|Bacilli	91061|Bacilli	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
GZD2_k127_860281_1	1198452.Jab_2c25790	1.1e-102	339.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,2WEJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
GZD2_k127_860281_6	436308.Nmar_0665	6.246e-10	64.0	COG3119@1|root,arCOG02785@2157|Archaea,41T3Q@651137|Thaumarchaeota	651137|Thaumarchaeota	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_867472_1	316274.Haur_2114	0.0002396	53.0	COG3903@1|root,COG3903@2|Bacteria,2GBRK@200795|Chloroflexi,376UZ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,TPR_12
GZD2_k127_867472_0	1123508.JH636440_gene2902	1.549e-42	160.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD2_k127_869930_2	1379270.AUXF01000001_gene2030	3.167e-39	151.0	COG0300@1|root,COG0300@2|Bacteria,1ZUD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD2_k127_869930_1	521098.Aaci_2021	3.264e-46	177.0	COG0500@1|root,COG2226@2|Bacteria,1V7TR@1239|Firmicutes,4HJ1N@91061|Bacilli	91061|Bacilli	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
GZD2_k127_869930_3	1163407.UU7_00150	7.914e-20	98.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1X823@135614|Xanthomonadales	135614|Xanthomonadales	O	Methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
GZD2_k127_869930_0	56780.SYN_02218	7.96e-161	517.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD2_k127_872759_1	926569.ANT_18100	4.325e-148	471.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
GZD2_k127_872759_0	926569.ANT_18090	2.404e-156	497.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GZD2_k127_872759_2	504728.K649_07620	1.351e-06	52.0	COG0491@1|root,COG0491@2|Bacteria,1WJ5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD2_k127_87422_5	1116472.MGMO_128c00150	6.053e-07	55.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XDJK@135618|Methylococcales	135618|Methylococcales	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD2_k127_87422_3	926569.ANT_27860	3.867e-21	100.0	COG3595@1|root,COG3595@2|Bacteria,2G73J@200795|Chloroflexi	200795|Chloroflexi	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
GZD2_k127_87422_1	479434.Sthe_2603	2.7e-35	147.0	COG3595@1|root,COG3595@2|Bacteria,2G73J@200795|Chloroflexi	200795|Chloroflexi	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
GZD2_k127_87422_4	555088.DealDRAFT_0112	1.521e-18	89.0	2FJYI@1|root,34BKW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_87422_0	1291050.JAGE01000002_gene3724	1.064e-43	171.0	292VP@1|root,2ZQD7@2|Bacteria,1W2HZ@1239|Firmicutes,257HA@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD2_k127_87422_2	889378.Spiaf_1447	4.695e-27	117.0	COG1475@1|root,COG1475@2|Bacteria,2J6CV@203691|Spirochaetes	203691|Spirochaetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_874731_0	471223.GWCH70_1081	1.384e-67	233.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1WEUB@129337|Geobacillus	91061|Bacilli	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
GZD2_k127_874731_3	926569.ANT_14620	3.963e-30	123.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GZD2_k127_874731_2	926569.ANT_14610	5.557e-54	193.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GZD2_k127_874731_4	926569.ANT_15060	1.775e-11	69.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GZD2_k127_874731_1	926569.ANT_15050	2.15e-56	208.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
GZD2_k127_8751_2	926550.CLDAP_11310	1.38e-95	322.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD2_k127_8751_0	926550.CLDAP_11320	1.182e-142	464.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD2_k127_8751_7	316274.Haur_0306	1.778e-21	100.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GZD2_k127_8751_1	926569.ANT_16410	3.081e-127	421.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GZD2_k127_8751_6	926569.ANT_16420	3.488e-26	112.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
GZD2_k127_8751_5	926569.ANT_16430	7.075e-45	166.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_8751_3	880073.Calab_1950	3.4e-87	294.0	COG0708@1|root,COG0708@2|Bacteria,2NP5K@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
GZD2_k127_8751_4	926569.ANT_20890	1.63e-69	241.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GZD2_k127_875144_4	926569.ANT_29000	1.961e-27	116.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GZD2_k127_875144_0	926569.ANT_29010	1.106e-138	446.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GZD2_k127_875144_3	926569.ANT_29020	5.581e-32	130.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GZD2_k127_875144_2	926569.ANT_02860	1.366e-93	319.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
GZD2_k127_875144_1	926569.ANT_02850	9.629e-103	338.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
GZD2_k127_879206_11	639282.DEFDS_1872	6.751e-09	61.0	2CIAQ@1|root,2ZXJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_879206_9	1136417.AZWE01000009_gene2169	3.686e-38	156.0	2F8JN@1|root,340YC@2|Bacteria,2INBZ@201174|Actinobacteria,4DECA@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_879206_3	926569.ANT_13390	4.276e-94	315.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
GZD2_k127_879206_6	1487953.JMKF01000043_gene2591	1.576e-88	306.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
GZD2_k127_879206_1	335543.Sfum_4027	1.179e-101	345.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
GZD2_k127_879206_0	543632.JOJL01000008_gene5929	8.205e-142	460.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DAII@85008|Micromonosporales	201174|Actinobacteria	E	Cys met metabolism pyridoxal-phosphate-dependent	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
GZD2_k127_879206_2	326427.Cagg_2948	2.754e-95	319.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi,375I3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
GZD2_k127_879206_5	485913.Krac_5625	1.313e-88	297.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GZD2_k127_879206_7	1041138.KB890221_gene1530	8.994e-65	236.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSK0@28211|Alphaproteobacteria,4B8BV@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Alcohol dehydrogenase, class IV	macA	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
GZD2_k127_879206_8	1298863.AUEP01000008_gene1241	1.904e-53	198.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
GZD2_k127_879206_4	1382306.JNIM01000001_gene1512	7.042e-90	300.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD2_k127_879206_10	1382306.JNIM01000001_gene1513	1.652e-32	133.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
GZD2_k127_879363_3	926550.CLDAP_10150	5.321e-48	179.0	COG2197@1|root,COG2197@2|Bacteria,2G8NX@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD2_k127_879363_2	926550.CLDAP_10140	1.719e-74	257.0	COG4585@1|root,COG4585@2|Bacteria,2G8N5@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD2_k127_879363_0	383372.Rcas_4375	1.563e-206	651.0	COG2224@1|root,COG2224@2|Bacteria,2G61J@200795|Chloroflexi,374VM@32061|Chloroflexia	32061|Chloroflexia	C	PFAM isocitrate lyase and phosphorylmutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
GZD2_k127_879363_1	309801.trd_0495	7.906e-87	291.0	COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,27Y0V@189775|Thermomicrobia	189775|Thermomicrobia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
GZD2_k127_886054_4	314292.VAS14_15634	4.231e-16	81.0	COG3042@1|root,COG3042@2|Bacteria,1QKE0@1224|Proteobacteria,1TIHX@1236|Gammaproteobacteria,1XZ5Q@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF333
GZD2_k127_886054_1	926569.ANT_22320	1.297e-107	360.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GZD2_k127_886054_3	926569.ANT_22310	5.158e-36	141.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GZD2_k127_886054_2	926569.ANT_22300	1.23e-67	248.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
GZD2_k127_886054_0	926550.CLDAP_01180	6.547e-150	491.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GZD2_k127_888257_0	926569.ANT_31620	9.88e-137	441.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GZD2_k127_888257_1	926569.ANT_31610	2.637e-91	316.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K16694	-	-	-	-	ko00000,ko02000	2.A.66.2.6	-	-	Polysacc_synt_3
GZD2_k127_888257_2	926569.ANT_00620	1.053e-29	126.0	COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GZD2_k127_888846_1	452637.Oter_3829	3e-48	186.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD2_k127_888846_0	84531.JMTZ01000059_gene2518	7.869e-63	225.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1X3GI@135614|Xanthomonadales	135614|Xanthomonadales	E	highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GZD2_k127_891942_0	1195236.CTER_0541	1.141e-282	885.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GZD2_k127_891942_3	1128421.JAGA01000002_gene1268	2.871e-20	95.0	COG0316@1|root,COG0316@2|Bacteria,2NPZK@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the HesB IscA family	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GZD2_k127_891942_1	926569.ANT_18580	5.576e-36	144.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GZD2_k127_891942_2	926569.ANT_18580	3.654e-27	122.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
GZD2_k127_891942_4	485913.Krac_0943	4.459e-07	59.0	2DRCD@1|root,33B7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_907288_1	118168.MC7420_7338	3.458e-63	229.0	2DTTJ@1|root,32UVW@2|Bacteria,1G8TS@1117|Cyanobacteria,1HCTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
GZD2_k127_907288_0	1205680.CAKO01000003_gene3681	7.452e-65	227.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
GZD2_k127_920302_0	926569.ANT_18670	2.06e-115	390.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
GZD2_k127_920302_1	926569.ANT_18690	1.102e-43	162.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD2_k127_925599_1	926569.ANT_06810	2.363e-63	224.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_925599_0	1128421.JAGA01000002_gene1836	5.926e-84	296.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
GZD2_k127_925599_2	926569.ANT_15760	9.428e-35	135.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
GZD2_k127_927133_1	1306174.JODP01000011_gene6834	2.21e-76	263.0	COG0412@1|root,COG0412@2|Bacteria,2HBMV@201174|Actinobacteria	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
GZD2_k127_927133_0	309801.trd_0440	1.291e-179	570.0	COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
GZD2_k127_927133_2	745776.DGo_CA0722	1.797e-42	179.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_26
GZD2_k127_927133_3	511051.CSE_02610	0.0001823	50.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771,ko:K07126	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Cu_amine_oxidN1,TPR_2,TPR_8,Trypsin_2,YceG_bac
GZD2_k127_928752_2	357808.RoseRS_2972	5.858e-18	83.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD2_k127_928752_1	357808.RoseRS_2971	3.584e-141	460.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD2_k127_928752_0	316274.Haur_4394	5.322e-221	707.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GZD2_k127_929817_1	373903.Hore_08780	4.387e-83	282.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WA8J@53433|Halanaerobiales	186801|Clostridia	S	PFAM ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GZD2_k127_929817_0	1313172.YM304_01530	2.493e-104	349.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
GZD2_k127_937082_2	1189619.pgond44_14073	2.602e-33	144.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_12,TPR_7
GZD2_k127_937082_1	326427.Cagg_1684	1.067e-45	174.0	COG1668@1|root,COG1668@2|Bacteria,2G9RA@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GZD2_k127_937082_0	251229.Chro_2593	6.391e-81	276.0	COG1131@1|root,COG1131@2|Bacteria,1GDU7@1117|Cyanobacteria	1117|Cyanobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD2_k127_941545_1	926569.ANT_09870	8.504e-101	339.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
GZD2_k127_941545_2	926569.ANT_09880	2.27e-79	276.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
GZD2_k127_941545_0	926569.ANT_09890	1.927e-104	355.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
GZD2_k127_950409_0	1306947.ARQD01000002_gene592	1.276e-220	694.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD2_k127_950409_5	83406.HDN1F_32740	1.212e-22	100.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the bacterial histone-like protein family	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
GZD2_k127_950409_1	404589.Anae109_4105	6.368e-151	496.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2YYYV@29|Myxococcales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GZD2_k127_950409_3	386456.JQKN01000002_gene2727	2.282e-57	203.0	COG0370@1|root,arCOG00359@2157|Archaea,2XU46@28890|Euryarchaeota,23NWG@183925|Methanobacteria	183925|Methanobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
GZD2_k127_950409_7	177437.HRM2_10920	4.161e-16	81.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
GZD2_k127_950409_4	861299.J421_4361	1.249e-41	161.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GZD2_k127_950409_2	443143.GM18_1260	1.401e-116	409.0	COG4251@1|root,COG4936@1|root,COG5000@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,dCache_1
GZD2_k127_950409_6	877455.Metbo_1101	7.153e-21	94.0	COG0784@1|root,arCOG02589@2157|Archaea,2XVUK@28890|Euryarchaeota	28890|Euryarchaeota	T	response regulator, receiver	rre-1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
GZD2_k127_95286_0	926569.ANT_22550	4.282e-97	326.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
GZD2_k127_959117_2	1499967.BAYZ01000089_gene5053	1.134e-21	99.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
GZD2_k127_959117_0	926569.ANT_04770	3.536e-163	553.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
GZD2_k127_959117_1	926569.ANT_00060	3.641e-34	147.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	rsbP	-	3.1.3.3	ko:K02660,ko:K07315,ko:K07814,ko:K17763	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko02022,ko02035,ko02044,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HD_5,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,STAS,SpoIIE
GZD2_k127_9630_2	398512.JQKC01000038_gene4571	2.342e-29	119.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3WJR9@541000|Ruminococcaceae	186801|Clostridia	KO	TIGRFAM hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
GZD2_k127_9630_1	926569.ANT_17840	4.441e-32	128.0	COG0375@1|root,COG0375@2|Bacteria,2G7H5@200795|Chloroflexi	200795|Chloroflexi	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GZD2_k127_9630_0	926569.ANT_17860	6.59e-149	488.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
GZD2_k127_96586_0	926569.ANT_15780	1.18e-246	769.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GZD2_k127_96586_1	926550.CLDAP_36260	1.235e-137	449.0	COG0463@1|root,COG0463@2|Bacteria,2G7KQ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_96586_2	926569.ANT_15820	1.733e-97	324.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
GZD2_k127_970744_10	1165096.ARWF01000001_gene462	4.409e-39	154.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KNQ0@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
GZD2_k127_970744_7	1165096.ARWF01000001_gene461	3.195e-87	296.0	COG0489@1|root,COG0489@2|Bacteria,1PHBP@1224|Proteobacteria,2W93I@28216|Betaproteobacteria,2KNKF@206350|Nitrosomonadales	206350|Nitrosomonadales	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_970744_0	1221522.B723_12380	1.6e-170	549.0	COG3307@1|root,COG3307@2|Bacteria,1RCKR@1224|Proteobacteria,1SJKS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD2_k127_970744_2	1101195.Meth11DRAFT_1097	6.988e-113	372.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2W936@28216|Betaproteobacteria,2KNBF@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
GZD2_k127_970744_1	76869.PputGB1_2718	4.98e-141	454.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD2_k127_970744_3	1101195.Meth11DRAFT_1105	4.295e-112	368.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,2KNQ7@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Viral (Superfamily 1) RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
GZD2_k127_970744_6	1267005.KB911259_gene4078	1.208e-99	337.0	2DX4H@1|root,32V2S@2|Bacteria,1RDDQ@1224|Proteobacteria,2UGTX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
GZD2_k127_970744_9	395494.Galf_1239	6.548e-47	174.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,44VTI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
GZD2_k127_970744_5	864702.OsccyDRAFT_0481	1.57e-104	354.0	COG2244@1|root,COG2244@2|Bacteria,1G3GP@1117|Cyanobacteria,1HH7B@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
GZD2_k127_970744_14	1499680.CCFE01000018_gene1193	0.0001951	44.0	2BPXI@1|root,32IR8@2|Bacteria,1UAVI@1239|Firmicutes,4IM8D@91061|Bacilli,1ZJGE@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_970744_4	1121035.AUCH01000009_gene854	5.072e-105	355.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
GZD2_k127_970744_8	1121004.ATVC01000055_gene616	2.761e-86	295.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,2KPDY@206351|Neisseriales	206351|Neisseriales	H	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
GZD2_k127_970744_11	395494.Galf_2194	6.691e-21	92.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2WCP5@28216|Betaproteobacteria,44WF7@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
GZD2_k127_970760_2	1121918.ARWE01000001_gene1548	4.745e-24	111.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD2_k127_970760_1	1125863.JAFN01000001_gene2936	3.274e-38	166.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07710	ko02020,map02020	M00500,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
GZD2_k127_970760_0	926569.ANT_16100	1.457e-155	495.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GZD2_k127_972219_2	742725.HMPREF9450_02328	3.203e-07	51.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FNCD@200643|Bacteroidia,22VRI@171550|Rikenellaceae	976|Bacteroidetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD2_k127_972219_0	926550.CLDAP_21610	1.637e-228	714.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD2_k127_972219_1	794903.OPIT5_14440	2.545e-182	584.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GZD2_k127_973972_9	443598.AUFA01000010_gene377	3.257e-18	85.0	2EC7F@1|root,33660@2|Bacteria,1N839@1224|Proteobacteria,2UFB7@28211|Alphaproteobacteria,3K1H1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_973972_3	926569.ANT_20460	2.326e-157	512.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GZD2_k127_973972_2	926569.ANT_20590	5.529e-159	507.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
GZD2_k127_973972_5	926569.ANT_14480	6.249e-107	352.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD2_k127_973972_11	1163407.UU7_06423	2.244e-15	79.0	COG1694@1|root,COG1694@2|Bacteria,1QSJB@1224|Proteobacteria,1RW18@1236|Gammaproteobacteria,1X808@135614|Xanthomonadales	135614|Xanthomonadales	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_973972_6	1303518.CCALI_02921	2.717e-100	343.0	COG0517@1|root,COG1227@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
GZD2_k127_973972_0	926569.ANT_14470	0.0	1507.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GZD2_k127_973972_8	526224.Bmur_0524	7.303e-42	175.0	2DSRT@1|root,33H76@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_973972_1	1499967.BAYZ01000019_gene6268	0.0	1068.0	COG1026@1|root,COG1026@2|Bacteria,2NQI2@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16C associated	CP_0875	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
GZD2_k127_973972_4	926569.ANT_19600	1.471e-148	477.0	COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD2_k127_973972_7	383372.Rcas_1313	7.596e-88	293.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD2_k127_973972_10	926569.ANT_14460	1.09e-17	85.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD2_k127_975218_3	443254.Marpi_0479	1.021e-31	131.0	COG2030@1|root,COG2030@2|Bacteria,2GD2R@200918|Thermotogae	200918|Thermotogae	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
GZD2_k127_975218_0	1170562.Cal6303_2142	1.408e-127	415.0	COG1209@1|root,COG1209@2|Bacteria,1G091@1117|Cyanobacteria,1HJMN@1161|Nostocales	1117|Cyanobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
GZD2_k127_975218_2	240015.ACP_1870	1.103e-74	254.0	COG1088@1|root,COG1088@2|Bacteria,3Y3E7@57723|Acidobacteria,2JIRI@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GZD2_k127_975703_2	357808.RoseRS_3403	1.251e-70	246.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD2_k127_975703_1	926569.ANT_18520	3.065e-83	282.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_975703_16	1110697.NCAST_13_01060	0.0005737	52.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4FX2G@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GZD2_k127_975703_14	1382356.JQMP01000001_gene1162	9.505e-10	67.0	COG1525@1|root,COG1525@2|Bacteria,2GB5G@200795|Chloroflexi,27Z81@189775|Thermomicrobia	189775|Thermomicrobia	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
GZD2_k127_975703_5	273068.TTE1095	1.253e-65	232.0	COG0348@1|root,COG0348@2|Bacteria,1V8RW@1239|Firmicutes,24JXS@186801|Clostridia,42GUZ@68295|Thermoanaerobacterales	186801|Clostridia	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_975703_0	926569.ANT_29120	8.642e-125	405.0	COG0348@1|root,COG0348@2|Bacteria,2G8SY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
GZD2_k127_975703_8	926569.ANT_00760	4.5e-47	175.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD2_k127_975703_9	596151.DesfrDRAFT_1297	3.432e-33	141.0	COG2203@1|root,COG2203@2|Bacteria,1RHTM@1224|Proteobacteria,42SY3@68525|delta/epsilon subdivisions,2WP4G@28221|Deltaproteobacteria,2MADU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
GZD2_k127_975703_15	697303.Thewi_0108	1.134e-07	61.0	COG4272@1|root,COG4272@2|Bacteria,1VAPQ@1239|Firmicutes,24MZV@186801|Clostridia,42GY3@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
GZD2_k127_975703_3	264732.Moth_0371	1.678e-68	241.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD2_k127_975703_13	1122176.KB903587_gene4538	1.855e-13	72.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GZD2_k127_975703_4	1521187.JPIM01000023_gene795	1.297e-66	233.0	COG0664@1|root,COG0664@2|Bacteria,2G8WB@200795|Chloroflexi	200795|Chloroflexi	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2
GZD2_k127_975703_12	926569.ANT_12030	3.999e-19	90.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GZD2_k127_975703_6	926569.ANT_12020	1.143e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD2_k127_975703_7	926569.ANT_28850	5.979e-54	192.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
GZD2_k127_975703_10	926569.ANT_12050	1.756e-25	110.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
GZD2_k127_982544_3	926550.CLDAP_05450	2.12e-73	252.0	COG1126@1|root,COG1126@2|Bacteria,2G6SU@200795|Chloroflexi	200795|Chloroflexi	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
GZD2_k127_982544_5	383372.Rcas_2183	1.448e-65	231.0	COG0765@1|root,COG0765@2|Bacteria,2G7X1@200795|Chloroflexi,377ZE@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
GZD2_k127_982544_6	926550.CLDAP_05430	3.043e-60	217.0	COG0834@1|root,COG0834@2|Bacteria,2G81G@200795|Chloroflexi	200795|Chloroflexi	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GZD2_k127_982544_10	1499967.BAYZ01000177_gene5750	1.41e-20	96.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	rplU	-	-	ko:K02879,ko:K02888,ko:K02890,ko:K02899,ko:K02967,ko:K04074	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03036	-	-	-	HHH_5,Ribosomal_L21p
GZD2_k127_982544_2	926554.KI912637_gene3425	2.667e-74	260.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GZD2_k127_982544_7	525904.Tter_2170	1.707e-51	188.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GZD2_k127_982544_1	1245471.PCA10_18760	3.992e-91	311.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1S070@1236|Gammaproteobacteria,1YF9G@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
GZD2_k127_982544_11	28072.Nos7524_5228	8.93e-13	72.0	2E4G4@1|root,32ZB9@2|Bacteria,1G9UK@1117|Cyanobacteria,1HNWN@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_982544_0	317936.Nos7107_1831	4.6e-141	458.0	COG3227@1|root,COG3227@2|Bacteria,1G3KW@1117|Cyanobacteria,1HMHN@1161|Nostocales	1117|Cyanobacteria	E	PFAM Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
GZD2_k127_982544_8	926569.ANT_07800	1.738e-49	183.0	COG1437@1|root,COG1437@2|Bacteria,2G9FW@200795|Chloroflexi	200795|Chloroflexi	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
GZD2_k127_982544_9	794903.OPIT5_14435	1.338e-27	117.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GZD2_k127_984451_1	926569.ANT_01910	2.153e-95	317.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
GZD2_k127_984451_0	926569.ANT_01920	6.774e-149	486.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GZD2_k127_984451_2	926569.ANT_29460	3.762e-58	206.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GZD2_k127_984451_3	1196322.A370_05424	5.265e-05	51.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,36DM2@31979|Clostridiaceae	186801|Clostridia	O	PDZ DHR GLGF domain protein	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD2_k127_984530_8	756067.MicvaDRAFT_0666	1.886e-28	115.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,1H9HM@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD2_k127_984530_1	926569.ANT_00500	1.605e-134	441.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
GZD2_k127_984530_9	1382306.JNIM01000001_gene144	3.505e-28	121.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GZD2_k127_984530_7	926569.ANT_02430	2.064e-52	193.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_984530_10	485913.Krac_12050	2.68e-23	105.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_984530_4	926569.ANT_30440	9.195e-67	239.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GZD2_k127_984530_2	1299327.I546_6086	2.162e-102	343.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,237RH@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD2_k127_984530_5	1462527.CCDM010000002_gene1513	6.872e-57	207.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
GZD2_k127_984530_11	1122137.AQXF01000004_gene1627	9.482e-23	102.0	COG3695@1|root,COG3695@2|Bacteria,1PZ1R@1224|Proteobacteria,2UWVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
GZD2_k127_984530_12	1521187.JPIM01000011_gene2651	1.092e-14	77.0	2ED7R@1|root,3374C@2|Bacteria,2GAGN@200795|Chloroflexi,3761Y@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD2_k127_984530_0	880073.Calab_0989	1.829e-151	485.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
GZD2_k127_984530_6	28072.Nos7524_0700	4.456e-55	196.0	COG4405@1|root,COG4405@2|Bacteria,1GE0T@1117|Cyanobacteria	1117|Cyanobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
GZD2_k127_984530_15	1120936.KB907209_gene1511	2.504e-06	56.0	2DQWT@1|root,33948@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD2_k127_984530_3	926569.ANT_05580	2.761e-100	332.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
GZD2_k127_984530_13	761193.Runsl_5201	2.106e-12	78.0	COG0823@1|root,COG0823@2|Bacteria,4P1IM@976|Bacteroidetes	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
GZD2_k127_984530_14	1172180.KB911776_gene665	4.96e-12	77.0	COG0739@1|root,COG0739@2|Bacteria,2GMJB@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
GZD2_k127_99455_8	926569.ANT_20660	1.044e-17	85.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GZD2_k127_99455_0	926569.ANT_20670	3.137e-112	370.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
GZD2_k127_99455_3	926569.ANT_20680	2.012e-48	183.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi	200795|Chloroflexi	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GZD2_k127_99455_2	926569.ANT_20690	2.797e-61	217.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
GZD2_k127_99455_1	326427.Cagg_0017	7.197e-72	249.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
GZD2_k127_99455_7	330779.Saci_1101	5.031e-19	94.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
GZD2_k127_99455_6	1499967.BAYZ01000145_gene6206	2.823e-27	114.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
GZD2_k127_99455_4	156889.Mmc1_0328	2.75e-47	178.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ptr1	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GZD2_k127_99455_5	1267534.KB906756_gene379	2.328e-30	132.0	COG3186@1|root,COG3186@2|Bacteria,3Y3K5@57723|Acidobacteria,2JHN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Biopterin-dependent aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
## 4128 queries scanned
## Total time (seconds): 88.15655374526978
## Rate: 46.83 q/s