## Sat Nov 16 00:20:50 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin7/GZD_3_bin.38.fa -m mmseqs --itype genome -o GZD_3_bin.38 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/GZD_3_bin.38 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
GZD3_k127_1016819_0	485913.Krac_4813	0.0	1489.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD3_k127_1016819_2	66373.JOFQ01000001_gene2005	8.572e-113	379.0	COG0657@1|root,COG0657@2|Bacteria,2I5U9@201174|Actinobacteria	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
GZD3_k127_1016819_8	485913.Krac_2770	9.07e-26	112.0	28Z60@1|root,2ZKYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1016819_4	266117.Rxyl_3168	2.124e-84	289.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4CPWT@84995|Rubrobacteria	84995|Rubrobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
GZD3_k127_1016819_1	485913.Krac_2271	3.579e-209	664.0	COG0318@1|root,COG0318@2|Bacteria,2G66U@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
GZD3_k127_1016819_3	1382356.JQMP01000001_gene1202	2.383e-92	313.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,27XR8@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
GZD3_k127_1016819_5	1382306.JNIM01000001_gene2543	1.692e-83	293.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene2543|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1016819_7	485913.Krac_11218	8.39e-47	188.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	MA20_39160	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
GZD3_k127_1023678_0	1169144.KB910935_gene2035	2.952e-51	189.0	COG1388@1|root,COG1388@2|Bacteria,1V4GT@1239|Firmicutes,4IPSP@91061|Bacilli	91061|Bacilli	M	LysM domain	M1-670	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1023678_1	945713.IALB_2285	5.176e-47	177.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GZD3_k127_1023678_2	1173027.Mic7113_0498	4.166e-28	124.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GZD3_k127_1023801_2	1382306.JNIM01000001_gene3639	1.969e-98	330.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
GZD3_k127_1023801_0	1386089.N865_19060	3.352e-176	562.0	2DCM0@1|root,2ZEJX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1023801_3	1242864.D187_008035	1.318e-52	205.0	2DBB1@1|root,2Z854@2|Bacteria,1RJH1@1224|Proteobacteria,43068@68525|delta/epsilon subdivisions,2WV9F@28221|Deltaproteobacteria,2YUXG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
GZD3_k127_1023801_1	485913.Krac_8725	3.764e-114	381.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GZD3_k127_1041356_0	485913.Krac_8713	4.806e-66	237.0	28MW3@1|root,2ZB3G@2|Bacteria,2G8UY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1041356_1	1382306.JNIM01000001_gene3951	8.534e-61	216.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi	200795|Chloroflexi	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
GZD3_k127_1041356_2	1382306.JNIM01000001_gene3950	9.521e-23	103.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GZD3_k127_1046494_2	575588.ACPN01000104_gene67	1.503e-09	59.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,3NKJ5@468|Moraxellaceae	1236|Gammaproteobacteria	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
GZD3_k127_1046494_1	935567.JAES01000004_gene76	1.45e-10	69.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
GZD3_k127_1046494_0	483219.LILAB_20025	5.678e-30	139.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales	28221|Deltaproteobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
GZD3_k127_105099_3	926569.ANT_05160	2.57e-33	137.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	3.2.1.8	ko:K01181,ko:K06889	-	-	-	-	ko00000,ko01000	-	-	-	-
GZD3_k127_105099_2	309801.trd_1094	2.779e-46	181.0	COG3897@1|root,COG3897@2|Bacteria,2GB9K@200795|Chloroflexi,27YC1@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
GZD3_k127_105099_0	518766.Rmar_2206	7.805e-64	231.0	COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,1FJWK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	-	-	1.3.1.25	ko:K05783	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
GZD3_k127_105099_1	1128421.JAGA01000002_gene1729	8.906e-49	189.0	COG2521@1|root,COG2521@2|Bacteria,2NQ9R@2323|unclassified Bacteria	2|Bacteria	S	Spermine/spermidine synthase domain	ypiP	-	2.1.1.242	ko:K06983,ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_30,SAM_MT
GZD3_k127_106536_5	1232410.KI421421_gene3299	3.478e-18	86.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K00446,ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GZD3_k127_106536_2	485913.Krac_6777	6.163e-63	229.0	COG3878@1|root,COG3878@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
GZD3_k127_106536_6	1120949.KB903312_gene608	9.066e-16	80.0	2B33I@1|root,31VR6@2|Bacteria,2GZHW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_106536_7	754477.Q7C_1483	0.0004719	48.0	COG4916@1|root,COG4916@2|Bacteria,1R81D@1224|Proteobacteria,1S7RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GZD3_k127_106536_0	1382306.JNIM01000001_gene348	4.145e-279	869.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GZD3_k127_106536_4	1411123.JQNH01000001_gene3003	7.857e-35	139.0	COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2UHEF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
GZD3_k127_106536_3	1382306.JNIM01000001_gene3059	2.867e-62	225.0	COG0500@1|root,COG2226@2|Bacteria,2G9SY@200795|Chloroflexi	200795|Chloroflexi	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GZD3_k127_106887_3	1123284.KB899071_gene1474	3.974e-22	105.0	COG1714@1|root,COG1714@2|Bacteria,1V7WG@1239|Firmicutes,4HK3X@91061|Bacilli	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
GZD3_k127_106887_1	485913.Krac_12238	1.789e-46	179.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
GZD3_k127_106887_2	118168.MC7420_7421	5.649e-23	106.0	COG1487@1|root,COG1487@2|Bacteria,1G6XP@1117|Cyanobacteria,1HCXG@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GZD3_k127_106887_0	1382306.JNIM01000001_gene1098	1.048e-89	309.0	COG2268@1|root,COG2268@2|Bacteria,2G7FP@200795|Chloroflexi	200795|Chloroflexi	S	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Flot
GZD3_k127_1075581_25	622637.KE124774_gene3696	7.128e-21	106.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TTSR@28211|Alphaproteobacteria,36ZPP@31993|Methylocystaceae	28211|Alphaproteobacteria	T	PAS fold	MA20_22735	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HATPase_c,HisKA,Response_reg
GZD3_k127_1075581_28	1128421.JAGA01000003_gene3540	4.453e-11	72.0	2E4CV@1|root,32Z89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2680
GZD3_k127_1075581_4	485913.Krac_2930	9.411e-198	627.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GZD3_k127_1075581_8	1382306.JNIM01000001_gene1675	5.32e-142	461.0	COG4608@1|root,COG4608@2|Bacteria,2G80T@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
GZD3_k127_1075581_10	1382306.JNIM01000001_gene1676	3.835e-125	413.0	COG0444@1|root,COG0444@2|Bacteria,2G6CC@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD3_k127_1075581_12	485913.Krac_2593	6.099e-109	362.0	COG1173@1|root,COG1173@2|Bacteria,2G88M@200795|Chloroflexi	2|Bacteria	EP	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
GZD3_k127_1075581_9	1382306.JNIM01000001_gene1739	4.175e-137	443.0	COG0601@1|root,COG0601@2|Bacteria,2G6RM@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD3_k127_1075581_3	1382306.JNIM01000001_gene1738	5.97e-225	712.0	COG0747@1|root,COG0747@2|Bacteria,2G880@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_1075581_5	485913.Krac_2214	1.924e-178	568.0	COG3538@1|root,COG3538@2|Bacteria	2|Bacteria	G	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
GZD3_k127_1075581_20	247639.MGP2080_11333	5.938e-44	170.0	COG4689@1|root,COG4689@2|Bacteria,1NDQG@1224|Proteobacteria,1SZYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
GZD3_k127_1075581_0	485913.Krac_0936	0.0	1110.0	COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,2G7SQ@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.14.14.1,1.6.2.4	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450
GZD3_k127_1075581_1	1254432.SCE1572_05710	2.492e-284	891.0	COG3408@1|root,COG3408@2|Bacteria,1QQ0U@1224|Proteobacteria	1224|Proteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_1075581_29	219305.MCAG_01657	2.643e-09	63.0	COG3255@1|root,COG3255@2|Bacteria,2GTJZ@201174|Actinobacteria,4DJ9B@85008|Micromonosporales	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD3_k127_1075581_2	2074.JNYD01000030_gene6652	5.628e-231	731.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4DX52@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GZD3_k127_1075581_14	1089553.Tph_c02430	9.479e-60	215.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,42EUQ@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_1075581_18	485913.Krac_2920	1.705e-52	206.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CheB_methylest,CheR,CheR_N,DUF3365,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
GZD3_k127_1075581_19	525904.Tter_2374	3.531e-51	206.0	COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2NQT3@2323|unclassified Bacteria	2|Bacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD3_k127_1075581_26	765911.Thivi_4079	4.823e-14	86.0	COG2202@1|root,COG4191@1|root,COG5000@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1S1P4@1236|Gammaproteobacteria,1WXRB@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4
GZD3_k127_1075581_30	690850.Desaf_2361	2.409e-08	61.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_1075581_15	485913.Krac_11878	2.188e-58	226.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_11878|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1075581_16	485913.Krac_10872	1.708e-54	216.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9
GZD3_k127_1075581_17	926550.CLDAP_21020	7.588e-54	201.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_1075581_7	1343740.M271_26945	2.015e-170	548.0	COG1215@1|root,COG1215@2|Bacteria,2GNN5@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferases probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GZD3_k127_1075581_6	1968.JOEV01000027_gene4624	1.977e-170	552.0	COG1807@1|root,COG1807@2|Bacteria,2H008@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_1075581_13	35754.JNYJ01000001_gene7388	1.688e-81	305.0	29342@1|root,2ZQM6@2|Bacteria,2I8PQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1075581_22	1382306.JNIM01000001_gene448	3.915e-37	163.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PP2C
GZD3_k127_1075581_27	479434.Sthe_2252	1.048e-12	76.0	COG0745@1|root,COG0745@2|Bacteria	479434.Sthe_2252|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1075581_21	429009.Adeg_1897	7.075e-40	158.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,25M0K@186801|Clostridia,42I9N@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_1075581_11	1382306.JNIM01000001_gene3941	5.762e-112	377.0	COG0726@1|root,COG2211@1|root,COG0726@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Polysacc_deac_1
GZD3_k127_1075581_24	653045.Strvi_8934	3.717e-26	114.0	COG2246@1|root,COG2246@2|Bacteria,2IPQJ@201174|Actinobacteria	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
GZD3_k127_1075581_23	420324.KI912045_gene4200	3.011e-26	114.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,1JTPR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GZD3_k127_1085185_0	572547.Amico_1476	3.012e-87	318.0	COG1158@1|root,COG1158@2|Bacteria,3TABC@508458|Synergistetes	508458|Synergistetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GZD3_k127_1085185_1	1206741.BAFX01000081_gene6256	1.422e-67	238.0	2C03A@1|root,2Z86B@2|Bacteria,2GMCC@201174|Actinobacteria,4G34B@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4291
GZD3_k127_1085185_3	1449357.JQLK01000003_gene2529	1.057e-15	79.0	2E3EN@1|root,32YDN@2|Bacteria,1WKIV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
GZD3_k127_1085185_4	643648.Slip_2012	1.206e-12	71.0	COG0776@1|root,COG0776@2|Bacteria,1UJ3U@1239|Firmicutes,24P9B@186801|Clostridia	186801|Clostridia	L	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GZD3_k127_1085185_2	309801.trd_A0237	2.213e-32	133.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi	200795|Chloroflexi	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GZD3_k127_1085185_5	796606.BMMGA3_14435	3.666e-11	63.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,1ZDFC@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
GZD3_k127_1088562_1	485913.Krac_11338	4.021e-113	369.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD3_k127_1088562_4	2045.KR76_02615	6.375e-06	54.0	2B5RN@1|root,31YM7@2|Bacteria,2I01X@201174|Actinobacteria,4DUZY@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
GZD3_k127_1088562_3	485913.Krac_11766	8.296e-60	214.0	COG0503@1|root,COG0503@2|Bacteria,2G8K9@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
GZD3_k127_1088562_0	485913.Krac_12476	3.244e-205	649.0	COG1418@1|root,COG1418@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
GZD3_k127_1088562_2	1382306.JNIM01000001_gene3501	7.496e-97	331.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GZD3_k127_1088562_5	1125973.JNLC01000010_gene1371	3.175e-05	51.0	COG0346@1|root,COG0346@2|Bacteria,1RFJX@1224|Proteobacteria,2U91E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_1111689_5	485913.Krac_8939	3.426e-56	205.0	COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GZD3_k127_1111689_1	1382306.JNIM01000001_gene4121	1.085e-101	345.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_1111689_3	1382306.JNIM01000001_gene4122	1.884e-67	242.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
GZD3_k127_1111689_8	1120948.KB903217_gene882	1.61e-17	94.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4E0NM@85010|Pseudonocardiales	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
GZD3_k127_1111689_6	1244869.H261_00235	3.18e-51	186.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,2JTFT@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
GZD3_k127_1111689_4	1382306.JNIM01000001_gene4124	1.117e-66	241.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
GZD3_k127_1111689_0	1382306.JNIM01000001_gene2944	1.568e-194	612.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi	200795|Chloroflexi	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
GZD3_k127_1111689_7	485913.Krac_8941	2.708e-20	96.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	DUF2087,HTH_20,HTH_5
GZD3_k127_1111689_2	485913.Krac_12340	7.248e-75	271.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT_2
GZD3_k127_1113203_8	1123518.ARWI01000001_gene1150	6.853e-09	68.0	COG1196@1|root,COG1196@2|Bacteria,1QUTY@1224|Proteobacteria,1T351@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
GZD3_k127_1113203_11	134676.ACPL_8175	2.388e-05	57.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
GZD3_k127_1113203_6	485913.Krac_3478	1.437e-22	105.0	2DU4Y@1|root,33NY5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1113203_2	1121946.AUAX01000001_gene2404	2.769e-110	375.0	COG0477@1|root,COG0477@2|Bacteria,2I6MD@201174|Actinobacteria,4DIAM@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_1113203_10	1121355.KB903377_gene290	1.116e-05	54.0	COG1846@1|root,COG1846@2|Bacteria,2GQN6@201174|Actinobacteria,22N5Y@1653|Corynebacteriaceae	201174|Actinobacteria	K	transcriptional	marR2	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
GZD3_k127_1113203_3	485913.Krac_3162	8.567e-78	275.0	COG1073@1|root,COG1073@2|Bacteria,2G8PF@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD3_k127_1113203_7	1380370.JIBA01000016_gene762	1.272e-11	72.0	2B1TT@1|root,31U9S@2|Bacteria,2GTPW@201174|Actinobacteria,4FHP5@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1113203_0	1173028.ANKO01000174_gene2710	2.513e-274	855.0	COG0021@1|root,COG0021@2|Bacteria,1G4GX@1117|Cyanobacteria,1HE47@1150|Oscillatoriales	1117|Cyanobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
GZD3_k127_1113203_9	485913.Krac_7500	2.615e-08	63.0	29XJV@1|root,30JAX@2|Bacteria,2G9FG@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1113203_5	1382306.JNIM01000001_gene461	8.451e-29	131.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
GZD3_k127_1113203_1	1382306.JNIM01000001_gene2359	1.75e-222	700.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
GZD3_k127_113202_10	479434.Sthe_2452	1.273e-23	103.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GZD3_k127_113202_8	1382306.JNIM01000001_gene1855	2.3e-35	142.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
GZD3_k127_113202_11	383372.Rcas_0280	8.637e-16	82.0	COG1734@1|root,COG1734@2|Bacteria,2G7BM@200795|Chloroflexi,377WS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM zinc finger, DksA TraR C4-type	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GZD3_k127_113202_16	72019.SARC_08830T0	2.923e-07	62.0	COG2453@1|root,KOG1716@2759|Eukaryota,38DF8@33154|Opisthokonta	33154|Opisthokonta	V	protein tyrosine/serine/threonine phosphatase activity	DUSP12	GO:0000003,GO:0000027,GO:0001932,GO:0001933,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006109,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008138,GO:0008150,GO:0008152,GO:0008270,GO:0009272,GO:0009653,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009968,GO:0009987,GO:0010494,GO:0010506,GO:0010508,GO:0010562,GO:0010563,GO:0010605,GO:0010638,GO:0010646,GO:0010648,GO:0010675,GO:0010676,GO:0010906,GO:0010927,GO:0016043,GO:0016239,GO:0016241,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0030684,GO:0030687,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031331,GO:0031399,GO:0031400,GO:0031505,GO:0032268,GO:0032269,GO:0032502,GO:0032505,GO:0032872,GO:0032873,GO:0032989,GO:0032991,GO:0033043,GO:0033131,GO:0033133,GO:0033673,GO:0033674,GO:0034293,GO:0034622,GO:0035335,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0042244,GO:0042254,GO:0042255,GO:0042273,GO:0042325,GO:0042326,GO:0042327,GO:0042546,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043412,GO:0043506,GO:0043508,GO:0043549,GO:0043933,GO:0043934,GO:0043935,GO:0044085,GO:0044087,GO:0044088,GO:0044089,GO:0044090,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045229,GO:0045859,GO:0045913,GO:0045936,GO:0045937,GO:0046328,GO:0046329,GO:0046872,GO:0046914,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051704,GO:0051716,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0065009,GO:0070302,GO:0070303,GO:0070590,GO:0070591,GO:0070726,GO:0070925,GO:0071554,GO:0071555,GO:0071704,GO:0071826,GO:0071840,GO:0071852,GO:0071900,GO:0071901,GO:0071940,GO:0080090,GO:0080134,GO:0080135,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1902531,GO:1902532,GO:1903046,GO:1903299,GO:1903301,GO:1990904,GO:2000785,GO:2000786	3.1.3.16,3.1.3.48	ko:K14819	-	-	-	-	ko00000,ko01000,ko01009,ko03009	-	-	-	DSPc
GZD3_k127_113202_13	357808.RoseRS_0678	1.134e-11	77.0	COG1404@1|root,COG1716@1|root,COG1404@2|Bacteria,COG1716@2|Bacteria,2G8R1@200795|Chloroflexi,376ZN@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Yop-YscD_cpl
GZD3_k127_113202_0	1382306.JNIM01000001_gene488	3.361e-149	488.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
GZD3_k127_113202_7	32057.KB217478_gene5965	7.883e-40	152.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HNP6@1161|Nostocales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GZD3_k127_113202_15	118168.MC7420_3784	2.544e-07	57.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_113202_14	1499967.BAYZ01000104_gene3688	6.811e-09	60.0	2E16Z@1|root,31VE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_113202_5	66373.JOFQ01000003_gene5771	3.733e-61	223.0	29AJG@1|root,2ZXJF@2|Bacteria,2GYRJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
GZD3_k127_113202_3	935863.AWZR01000009_gene61	9.575e-85	297.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,1RSMJ@1236|Gammaproteobacteria,1X4P7@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
GZD3_k127_113202_4	1120950.KB892720_gene1829	9.257e-64	224.0	COG1309@1|root,COG1309@2|Bacteria,2IPAX@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_113202_1	994479.GL877878_gene1555	1.549e-139	453.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX69@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	1.14.19.8	ko:K17476	ko01130,map01130	M00819	R10162	RC03132	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
GZD3_k127_113202_9	242159.ABO95166	5.092e-30	127.0	COG0461@1|root,KOG1377@2759|Eukaryota,37INB@33090|Viridiplantae,34H72@3041|Chlorophyta	3041|Chlorophyta	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	PYR5	-	2.4.2.10,4.1.1.23	ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
GZD3_k127_113202_2	369723.Strop_1857	8.512e-105	353.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4D96V@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GZD3_k127_1156874_2	485913.Krac_12090	2.719e-45	171.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2778,PG_binding_1,YkuD
GZD3_k127_1156874_3	1382306.JNIM01000001_gene98	1.063e-44	171.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
GZD3_k127_1156874_1	1382306.JNIM01000001_gene1437	2.847e-62	237.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GZD3_k127_1156874_0	1382306.JNIM01000001_gene3941	5.092e-110	368.0	COG0726@1|root,COG2211@1|root,COG0726@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Polysacc_deac_1
GZD3_k127_1158028_6	479434.Sthe_1541	7.775e-77	261.0	2E5KE@1|root,3385H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1158028_1	402881.Plav_3468	9.407e-102	344.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,1JPFT@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
GZD3_k127_1158028_9	1096546.WYO_1994	5.159e-21	96.0	COG3293@1|root,COG3293@2|Bacteria,1REVC@1224|Proteobacteria,2U6ZB@28211|Alphaproteobacteria,1JW8N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
GZD3_k127_1158028_3	485913.Krac_10273	1.322e-91	318.0	COG1194@1|root,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
GZD3_k127_1158028_7	525904.Tter_2843	1.58e-64	228.0	COG2095@1|root,COG2095@2|Bacteria,2NRH5@2323|unclassified Bacteria	2|Bacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
GZD3_k127_1158028_8	485913.Krac_9801	2.249e-59	222.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_1158028_4	485913.Krac_9799	1.704e-90	309.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_1158028_5	266117.Rxyl_2030	3.266e-77	275.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CPB4@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_1158028_0	485913.Krac_9797	1.381e-103	342.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD3_k127_1158028_2	485913.Krac_9796	1.984e-100	337.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_117221_4	635013.TherJR_0951	0.0001702	54.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
GZD3_k127_117221_3	1304275.C41B8_16824	5.608e-05	56.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,1RP38@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
GZD3_k127_117221_1	1173028.ANKO01000227_gene1230	3.742e-83	293.0	COG2124@1|root,COG2124@2|Bacteria,1G28M@1117|Cyanobacteria,1H767@1150|Oscillatoriales	1117|Cyanobacteria	C	Cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GZD3_k127_117221_0	309801.trd_0711	4.503e-110	361.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD3_k127_1189651_1	1382306.JNIM01000001_gene368	2.267e-20	104.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene368|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1189651_0	1382306.JNIM01000001_gene2563	6.87e-111	366.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
GZD3_k127_1190381_12	1382306.JNIM01000001_gene600	2.794e-43	168.0	COG3127@1|root,COG3127@2|Bacteria,2G7QS@200795|Chloroflexi	200795|Chloroflexi	Q	COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD3_k127_1190381_10	479434.Sthe_0106	2.913e-56	215.0	COG3371@1|root,COG3371@2|Bacteria,2G95R@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GZD3_k127_1190381_6	266117.Rxyl_2810	5.064e-81	294.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
GZD3_k127_1190381_4	266117.Rxyl_2809	3.165e-96	327.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CRNI@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_1190381_5	485913.Krac_2637	9.096e-96	344.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GZD3_k127_1190381_0	485913.Krac_2637	1.083e-162	538.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GZD3_k127_1190381_2	82654.Pse7367_0547	7.199e-140	459.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
GZD3_k127_1190381_15	485913.Krac_2639	1.403e-32	136.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD3_k127_1190381_14	497964.CfE428DRAFT_0450	3.038e-37	157.0	COG0515@1|root,COG0515@2|Bacteria,46W45@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1190381_20	326424.FRAAL6485	8.88e-11	74.0	COG0631@1|root,COG0631@2|Bacteria,2IE0P@201174|Actinobacteria	201174|Actinobacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
GZD3_k127_1190381_17	66874.JOFS01000045_gene11	3.412e-29	132.0	COG2304@1|root,COG2304@2|Bacteria,2I4PE@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1190381_9	526227.Mesil_2547	6.461e-63	222.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
GZD3_k127_1190381_1	1128421.JAGA01000003_gene3727	4.396e-153	490.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
GZD3_k127_1190381_7	1382306.JNIM01000001_gene2855	6.704e-78	269.0	COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi	200795|Chloroflexi	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
GZD3_k127_1190381_16	452652.KSE_73600	1.929e-31	143.0	COG0500@1|root,COG1695@1|root,COG1695@2|Bacteria,COG2226@2|Bacteria,2HF3G@201174|Actinobacteria,2M5TZ@2063|Kitasatospora	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_1190381_11	485913.Krac_1345	9.277e-45	166.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
GZD3_k127_1190381_8	479434.Sthe_1453	7.207e-75	263.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi,27YDK@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GZD3_k127_1190381_3	479434.Sthe_1454	9.824e-101	340.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi,27YNK@189775|Thermomicrobia	189775|Thermomicrobia	P	NMT1-like family	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
GZD3_k127_1190381_18	1382306.JNIM01000001_gene847	3.729e-17	94.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene847|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1190381_21	1121946.AUAX01000008_gene7374	8.733e-07	61.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GZD3_k127_1190868_1	1172188.KB911824_gene3355	1.238e-20	108.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria,4FIAP@85021|Intrasporangiaceae	201174|Actinobacteria	S	PQQ-like domain	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
GZD3_k127_1190868_0	383372.Rcas_1701	2.431e-65	237.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi,3780Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_1193410_0	485913.Krac_11099	1.247e-126	415.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GZD3_k127_1216371_6	1123320.KB889741_gene5169	4.771e-57	211.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GZD3_k127_1216371_3	67352.JODS01000008_gene7297	8.405e-95	321.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_1216371_4	485913.Krac_6843	1.989e-92	309.0	COG0745@1|root,COG0745@2|Bacteria,2G6MM@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_1216371_2	485913.Krac_6303	1.085e-95	333.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_1216371_8	999541.bgla_1g10670	6.502e-12	72.0	2DPAY@1|root,331AT@2|Bacteria,1N6ZM@1224|Proteobacteria,2W4VP@28216|Betaproteobacteria,1K7GP@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
GZD3_k127_1216371_0	485913.Krac_1851	7.559e-175	577.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD3_k127_1216371_1	485913.Krac_6306	1.71e-103	342.0	COG1136@1|root,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_1216371_7	1068980.ARVW01000001_gene4238	7.865e-38	149.0	COG0500@1|root,COG2226@2|Bacteria,2GTD4@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_1216371_5	479434.Sthe_0717	9.46e-60	212.0	2BCVK@1|root,326GC@2|Bacteria,2G9HU@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3995)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3995
GZD3_k127_122491_0	266117.Rxyl_0316	2.045e-154	497.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
GZD3_k127_122491_5	1408428.JNJP01000029_gene593	5.38e-16	91.0	COG3884@1|root,COG3884@2|Bacteria,1NBT0@1224|Proteobacteria,42UNR@68525|delta/epsilon subdivisions,2WR29@28221|Deltaproteobacteria,2MGGK@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
GZD3_k127_122491_2	485913.Krac_10501	5.463e-75	258.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
GZD3_k127_122491_6	1276920.ADIAG_03882	1.688e-09	70.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_122491_1	485913.Krac_2581	1.241e-126	414.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GZD3_k127_122491_3	316274.Haur_2430	2.209e-50	185.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_122491_4	240015.ACP_3304	3.541e-42	159.0	COG3548@1|root,COG3548@2|Bacteria,3Y607@57723|Acidobacteria,2JMVT@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD3_k127_1225835_3	1382306.JNIM01000001_gene3274	4.025e-124	428.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
GZD3_k127_1225835_5	1382306.JNIM01000001_gene958	4.355e-70	254.0	COG0392@1|root,COG0392@2|Bacteria,2G96U@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
GZD3_k127_1225835_2	1382306.JNIM01000001_gene957	5.879e-125	410.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_1225835_0	479434.Sthe_2463	1.652e-134	438.0	COG0665@1|root,COG0665@2|Bacteria,2G6QE@200795|Chloroflexi,27Y6M@189775|Thermomicrobia	2|Bacteria	E	NAD(P)-binding Rossmann-like domain	yurR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
GZD3_k127_1225835_4	266117.Rxyl_0440	2.35e-70	245.0	COG1309@1|root,COG1309@2|Bacteria,2HFWT@201174|Actinobacteria,4CTT8@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GZD3_k127_1225835_1	1386089.N865_07610	3.005e-130	443.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GZD3_k127_1231198_0	479434.Sthe_0483	5.682e-83	288.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	2|Bacteria	E	peptidase dimerisation domain protein	cpg2	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD3_k127_1231198_1	1382306.JNIM01000001_gene292	3.533e-59	213.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GZD3_k127_123400_1	926569.ANT_13990	1.25e-53	192.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD3_k127_123400_0	926569.ANT_13980	2.139e-108	357.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD3_k127_123400_2	309801.trd_1054	8.851e-08	56.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GZD3_k127_1245262_1	1382306.JNIM01000001_gene1224	9.279e-153	492.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
GZD3_k127_1245262_0	1380393.JHVP01000005_gene3704	2.558e-223	697.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EURB@85013|Frankiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GZD3_k127_1245262_2	221288.JH992900_gene391	2.341e-122	402.0	COG2267@1|root,COG2267@2|Bacteria,1G000@1117|Cyanobacteria,1JMHA@1189|Stigonemataceae	1117|Cyanobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
GZD3_k127_1245262_7	324602.Caur_0393	3.319e-49	179.0	COG0757@1|root,COG0757@2|Bacteria,2G6N1@200795|Chloroflexi,3775Y@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
GZD3_k127_1245262_5	235909.GK2411	1.474e-87	311.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1WEYN@129337|Geobacillus	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	yqhT	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GZD3_k127_1245262_6	1382306.JNIM01000001_gene1345	6.161e-76	259.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
GZD3_k127_1245262_9	1128421.JAGA01000004_gene2523	2.696e-22	106.0	COG0511@1|root,COG0511@2|Bacteria,2NPT1@2323|unclassified Bacteria	2|Bacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.3.1.12	ko:K00627,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03664	Biotin_lipoyl
GZD3_k127_1245262_3	1382306.JNIM01000001_gene1347	5.574e-115	388.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
GZD3_k127_1245262_10	637910.ROD_04711	2.15e-07	60.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,3WYVI@544|Citrobacter	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
GZD3_k127_1245262_8	485913.Krac_7765	1.167e-41	158.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
GZD3_k127_1245262_4	1382306.JNIM01000001_gene2581	3.015e-102	340.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
GZD3_k127_128018_1	446470.Snas_3707	0.0008473	52.0	COG0790@1|root,COG0790@2|Bacteria,2I33U@201174|Actinobacteria	201174|Actinobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_128018_0	1382306.JNIM01000001_gene3411	2.534e-38	150.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
GZD3_k127_1297693_3	1382306.JNIM01000001_gene2872	1.211e-09	60.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
GZD3_k127_1297693_2	485913.Krac_11308	5.5e-27	122.0	2APF0@1|root,31EHN@2|Bacteria,2G7DI@200795|Chloroflexi	200795|Chloroflexi	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
GZD3_k127_1297693_4	1303518.CCALI_01831	3.747e-09	68.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,His_Phos_1
GZD3_k127_1297693_0	1120936.KB907221_gene2106	4.858e-124	409.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4EJJ1@85012|Streptosporangiales	201174|Actinobacteria	CH	FAD binding domain	-	GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018669,GO:0019439,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.14.13.24	ko:K22270	ko00362,ko01120,map00362,map01120	-	R02589	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
GZD3_k127_1297693_1	1120949.KB903314_gene297	3.811e-78	272.0	COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_1300041_3	765420.OSCT_2742	7.449e-35	153.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
GZD3_k127_1300041_1	485913.Krac_11482	6.261e-137	457.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GZD3_k127_1300041_4	324602.Caur_2448	2.225e-28	124.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096,Resolvase
GZD3_k127_1300041_5	571166.KI421509_gene2309	1.933e-15	85.0	COG2329@1|root,COG2329@2|Bacteria,1N1IT@1224|Proteobacteria,2UCHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD3_k127_1300041_0	357808.RoseRS_2284	2.332e-180	574.0	COG0863@1|root,COG0863@2|Bacteria,2G7IH@200795|Chloroflexi,376KM@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_1300041_2	383372.Rcas_4398	1.446e-100	334.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_1325633_1	521098.Aaci_0147	4.042e-74	252.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli	91061|Bacilli	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
GZD3_k127_1325633_6	163908.KB235896_gene3921	7.969e-16	80.0	COG4118@1|root,COG4118@2|Bacteria,1G9W7@1117|Cyanobacteria,1HQ2S@1161|Nostocales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,PhdYeFM_antitox
GZD3_k127_1325633_3	357808.RoseRS_1995	4.976e-48	175.0	COG3744@1|root,COG3744@2|Bacteria,2G9CV@200795|Chloroflexi,377FA@32061|Chloroflexia	32061|Chloroflexia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_1325633_0	56107.Cylst_4096	5.713e-177	565.0	COG2312@1|root,COG2312@2|Bacteria,1GK9Y@1117|Cyanobacteria,1HMEE@1161|Nostocales	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
GZD3_k127_1325633_5	326427.Cagg_3296	3.163e-38	153.0	2EDP2@1|root,337IR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
GZD3_k127_1325633_11	1340493.JNIF01000004_gene1054	9.347e-06	56.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_16,TPR_8,gag-asp_proteas
GZD3_k127_1325633_7	1216007.AOPM01000096_gene463	1.627e-14	82.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,2PZKN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	CM	COG1042 Acyl-CoA synthetase (NDP forming)	yfiQ	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GZD3_k127_1325633_4	1038858.AXBA01000057_gene4927	1.28e-38	153.0	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,2TVF4@28211|Alphaproteobacteria,3EZB8@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GZD3_k127_1325633_8	448385.sce5215	7.188e-10	60.0	COG3293@1|root,COG3293@2|Bacteria,1REUV@1224|Proteobacteria,434N6@68525|delta/epsilon subdivisions,2WYZI@28221|Deltaproteobacteria,2Z104@29|Myxococcales	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
GZD3_k127_1325633_10	1463887.KL589990_gene1068	1.952e-06	52.0	2C8AY@1|root,331RE@2|Bacteria,2HPG4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1325633_9	1278073.MYSTI_00466	3.13e-08	62.0	COG2365@1|root,COG2365@2|Bacteria,1QX58@1224|Proteobacteria,43BXZ@68525|delta/epsilon subdivisions,2X78T@28221|Deltaproteobacteria,2YWT7@29|Myxococcales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
GZD3_k127_1325633_2	357808.RoseRS_1377	2.282e-62	220.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi,3770T@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
GZD3_k127_1345720_3	479434.Sthe_2726	5.269e-87	291.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD3_k127_1345720_12	111780.Sta7437_3487	1.67e-14	75.0	COG1724@1|root,COG1724@2|Bacteria,1G8YW@1117|Cyanobacteria,3VKNR@52604|Pleurocapsales	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_1345720_13	1148.1673347	1.079e-13	76.0	COG1598@1|root,COG1598@2|Bacteria,1G8ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_1345720_5	485913.Krac_4459	5.49e-65	230.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD3_k127_1345720_11	401526.TcarDRAFT_0302	1.201e-18	94.0	COG3238@1|root,COG3238@2|Bacteria,1V6JD@1239|Firmicutes,4H4V5@909932|Negativicutes	909932|Negativicutes	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
GZD3_k127_1345720_2	2002.JOEQ01000004_gene2685	4.513e-92	308.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4EGF5@85012|Streptosporangiales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
GZD3_k127_1345720_9	1121924.ATWH01000006_gene1810	2.448e-23	113.0	28JRZ@1|root,2Z9HI@2|Bacteria,2H9EF@201174|Actinobacteria,4FNVC@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
GZD3_k127_1345720_1	68570.DC74_564	2.886e-133	434.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GZD3_k127_1345720_7	479434.Sthe_0209	1.189e-56	206.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
GZD3_k127_1345720_8	1382306.JNIM01000001_gene68	1.023e-25	111.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene68|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1345720_4	1382306.JNIM01000001_gene69	1.909e-71	271.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	ladS	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,HisKA_7TM,Response_reg,TPR_12,TPR_8
GZD3_k127_1345720_0	485913.Krac_8878	2.026e-143	468.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GZD3_k127_1346286_1	146922.JOFU01000012_gene1850	5.265e-64	228.0	COG1378@1|root,COG1378@2|Bacteria,2IB4E@201174|Actinobacteria	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
GZD3_k127_1346286_0	485913.Krac_11648	1.816e-304	983.0	28KV5@1|root,2ZABS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GZD3_k127_1346286_3	383372.Rcas_3538	1.39e-40	168.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD3_k127_1346286_2	1382306.JNIM01000001_gene3566	2.051e-55	198.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
GZD3_k127_134741_2	309801.trd_1606	1.914e-82	281.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_134741_1	1382306.JNIM01000001_gene3489	1.434e-121	396.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
GZD3_k127_134741_0	485913.Krac_8732	6.792e-268	835.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GZD3_k127_134741_3	1382306.JNIM01000001_gene3491	6.704e-42	158.0	COG2142@1|root,COG2142@2|Bacteria,2G7EN@200795|Chloroflexi	200795|Chloroflexi	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GZD3_k127_134741_4	1382306.JNIM01000001_gene3492	3.085e-33	131.0	COG2009@1|root,COG2009@2|Bacteria,2G7CW@200795|Chloroflexi	200795|Chloroflexi	C	succinate dehydrogenase, cytochrome	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
GZD3_k127_1352321_5	373994.Riv7116_1719	0.0006341	44.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HPKY@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1352321_4	485913.Krac_12389	1.629e-19	97.0	COG1595@1|root,COG1595@2|Bacteria,2G9AH@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_1352321_0	1382306.JNIM01000001_gene873	7.538e-123	406.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
GZD3_k127_1352321_3	1223542.GM1_002_01020	1.721e-26	126.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,4GCXB@85026|Gordoniaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Lpp-LpqN,Pkinase
GZD3_k127_1352321_2	1394178.AWOO02000004_gene2433	8.517e-99	331.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_1352321_1	485913.Krac_11072	2.257e-112	371.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD3_k127_1369775_10	485913.Krac_12388	1.68e-05	51.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2,PQQ_3
GZD3_k127_1369775_5	485913.Krac_12389	4.232e-53	202.0	COG1595@1|root,COG1595@2|Bacteria,2G9AH@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_1369775_1	390989.JOEG01000017_gene6236	1.714e-69	251.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4DDCM@85008|Micromonosporales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
GZD3_k127_1369775_9	709986.Deima_2486	7.179e-09	66.0	COG0735@1|root,COG0735@2|Bacteria,1WJYT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GZD3_k127_1369775_6	1382306.JNIM01000001_gene3668	2.72e-48	188.0	COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_1369775_4	1382306.JNIM01000001_gene4038	2.031e-54	202.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GZD3_k127_1369775_8	485913.Krac_10686	3.883e-10	64.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2G82S@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A7NFQ2 Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_1369775_2	1172179.AUKV01000004_gene6548	5.743e-68	237.0	COG1309@1|root,COG1309@2|Bacteria,2IIFY@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_1369775_0	1380390.JIAT01000009_gene2106	2.235e-168	534.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4CPX2@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD3_k127_1369775_3	1444309.JAQG01000162_gene1867	7.795e-63	222.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,26WUE@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GZD3_k127_1369775_7	266117.Rxyl_2565	7.452e-18	84.0	COG2128@1|root,COG2128@2|Bacteria,2HSVU@201174|Actinobacteria,4CQMM@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD3_k127_1369836_1	383372.Rcas_1096	7.768e-57	211.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,374RW@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GZD3_k127_1369836_0	926569.ANT_23380	1.073e-130	427.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
GZD3_k127_1372940_2	1089553.Tph_c26450	1.465e-130	430.0	COG0438@1|root,COG0438@2|Bacteria,1TS4X@1239|Firmicutes,24BYU@186801|Clostridia,42F0Q@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GZD3_k127_1372940_1	1120936.KB907219_gene3171	6.039e-154	514.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EG9Z@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GZD3_k127_1372940_0	1382306.JNIM01000001_gene2606	8.803e-162	518.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	200795|Chloroflexi	E	aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD3_k127_1386199_3	296591.Bpro_1544	2.244e-05	56.0	28M95@1|root,2ZAN4@2|Bacteria,1R588@1224|Proteobacteria,2W0AN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
GZD3_k127_1386199_1	1382306.JNIM01000001_gene445	3.535e-69	253.0	COG0477@1|root,COG2271@1|root,COG2271@2|Bacteria,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_1386199_2	1382306.JNIM01000001_gene1581	1.244e-53	193.0	COG0822@1|root,COG0822@2|Bacteria,2G6WC@200795|Chloroflexi	200795|Chloroflexi	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GZD3_k127_1386199_0	42256.RradSPS_0358	2.451e-152	501.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GZD3_k127_1404625_10	1214101.BN159_4996	1.273e-10	68.0	COG1075@1|root,COG1075@2|Bacteria,2I5S6@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF676
GZD3_k127_1404625_8	765420.OSCT_2742	2.924e-43	173.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
GZD3_k127_1404625_0	1382306.JNIM01000001_gene1332	2.091e-111	368.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
GZD3_k127_1404625_5	485913.Krac_7780	2.408e-64	226.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
GZD3_k127_1404625_3	1382306.JNIM01000001_gene1334	2.485e-96	323.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
GZD3_k127_1404625_4	1382306.JNIM01000001_gene1335	1.98e-68	237.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
GZD3_k127_1404625_2	1382306.JNIM01000001_gene1336	8.059e-101	338.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
GZD3_k127_1404625_6	1382306.JNIM01000001_gene1337	5.393e-58	214.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
GZD3_k127_1404625_7	485913.Krac_2703	2.196e-44	167.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	ydaG	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyrid_ox_like
GZD3_k127_1404625_1	485913.Krac_4668	4.048e-110	362.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD3_k127_1404625_9	1396141.BATP01000003_gene5002	2.308e-20	99.0	COG1670@1|root,COG1670@2|Bacteria,46U79@74201|Verrucomicrobia,2IVSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1411917_2	1157638.KB892164_gene3433	6.106e-17	84.0	2CDI4@1|root,32YR4@2|Bacteria,2IINI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1411917_1	251229.Chro_2277	2.201e-26	112.0	COG1487@1|root,COG1487@2|Bacteria,1G6XP@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GZD3_k127_1411917_3	1192034.CAP_1544	1.436e-15	89.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
GZD3_k127_1411917_0	1007103.AFHW01000001_gene4885	2.249e-50	188.0	COG3173@1|root,COG3173@2|Bacteria,1VIJ4@1239|Firmicutes,4HQI2@91061|Bacilli,274RM@186822|Paenibacillaceae	91061|Bacilli	K	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_142253_3	485913.Krac_12256	8.238e-72	245.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GZD3_k127_142253_5	485913.Krac_9379	5.452e-50	183.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_142253_1	485913.Krac_7205	1.004e-131	433.0	COG3214@1|root,COG3214@2|Bacteria,2G7W1@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GZD3_k127_142253_0	1382306.JNIM01000001_gene2868	9.093e-167	543.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
GZD3_k127_142253_2	930169.B5T_04337	7.554e-72	250.0	COG3217@1|root,COG3217@2|Bacteria,1Q80Q@1224|Proteobacteria,1SFUE@1236|Gammaproteobacteria,1XPA1@135619|Oceanospirillales	135619|Oceanospirillales	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GZD3_k127_142253_6	448385.sce6725	2.119e-47	179.0	COG3217@1|root,COG3217@2|Bacteria,1N1P0@1224|Proteobacteria,43024@68525|delta/epsilon subdivisions,2X3J5@28221|Deltaproteobacteria,2YWAG@29|Myxococcales	28221|Deltaproteobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GZD3_k127_142253_7	330214.NIDE3532	1.141e-16	81.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GZD3_k127_142253_4	443255.SCLAV_1880	1.882e-69	246.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	Lumazine_bd_2,NAD_binding_11,NAD_binding_2,Ribonuc_L-PSP
GZD3_k127_142253_8	1122223.KB890688_gene1451	7.45e-12	66.0	COG1670@1|root,COG1670@2|Bacteria,1WJG0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128,2.3.1.82	ko:K00663,ko:K03790	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Acetyltransf_3
GZD3_k127_1448428_0	1162668.LFE_0642	3.571e-193	630.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	40117|Nitrospirae	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
GZD3_k127_1448428_3	1382306.JNIM01000001_gene532	6.515e-50	186.0	COG0406@1|root,COG0406@2|Bacteria,2G726@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD3_k127_1448428_2	1382306.JNIM01000001_gene171	1.739e-112	381.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
GZD3_k127_1448428_4	1123388.AQWU01000065_gene2017	6.219e-27	122.0	COG2045@1|root,COG2045@2|Bacteria,1WJBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
GZD3_k127_1448428_1	485913.Krac_12071	7.898e-122	409.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD3_k127_1448428_5	1382306.JNIM01000001_gene3600	1.132e-25	110.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
GZD3_k127_1448428_7	1500897.JQNA01000002_gene2979	4.592e-08	62.0	28JAP@1|root,2Z95J@2|Bacteria,1N7JU@1224|Proteobacteria,2WC01@28216|Betaproteobacteria,1K6ZG@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1448428_6	485913.Krac_2242	4.801e-24	110.0	COG0665@1|root,COG0665@2|Bacteria,2G7VQ@200795|Chloroflexi	200795|Chloroflexi	E	PFAM FAD dependent oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
GZD3_k127_1450079_2	1440774.Y900_028070	1.076e-104	353.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,2387G@1762|Mycobacteriaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
GZD3_k127_1450079_18	309801.trd_0948	6.925e-10	69.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_1450079_3	1048339.KB913029_gene493	9.284e-92	320.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4ESCB@85013|Frankiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GZD3_k127_1450079_8	479432.Sros_7067	3.739e-37	149.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4EH0E@85012|Streptosporangiales	201174|Actinobacteria	CJ	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GZD3_k127_1450079_10	1382356.JQMP01000003_gene1440	4.062e-29	130.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1450079_15	743525.TSC_c24940	3.082e-16	83.0	COG0205@1|root,COG0205@2|Bacteria,1WINW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GZD3_k127_1450079_4	1121382.JQKG01000012_gene236	1.262e-64	229.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GZD3_k127_1450079_20	521098.Aaci_2135	0.0001189	50.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,277W3@186823|Alicyclobacillaceae	91061|Bacilli	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
GZD3_k127_1450079_1	926569.ANT_28310	1.842e-134	438.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
GZD3_k127_1450079_0	383372.Rcas_4052	0.0	1654.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2G5M1@200795|Chloroflexi,376VN@32061|Chloroflexia	32061|Chloroflexia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
GZD3_k127_1450079_14	1121272.KB903290_gene4684	2.029e-21	106.0	2CBE1@1|root,32RT5@2|Bacteria,2IQDS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1450079_12	1121272.KB903290_gene4684	1.176e-26	114.0	2CBE1@1|root,32RT5@2|Bacteria,2IQDS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1450079_9	485913.Krac_10686	6.596e-30	135.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2G82S@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A7NFQ2 Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_1450079_17	570967.JMLV01000009_gene982	1.271e-10	64.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,2JSK6@204441|Rhodospirillales	204441|Rhodospirillales	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	tnpF	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_1450079_7	1240349.ANGC01000047_gene4661	6.621e-39	163.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,4G0EJ@85025|Nocardiaceae	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
GZD3_k127_1450079_19	243164.DET0736	1.732e-05	52.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi,34CMA@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GZD3_k127_1450079_11	525904.Tter_2547	1.585e-28	127.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1450079_5	485913.Krac_7240	2.11e-60	222.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1450079_6	1382306.JNIM01000001_gene2393	5.472e-56	214.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
GZD3_k127_1450079_16	886293.Sinac_0723	4.348e-14	78.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_1450079_13	485913.Krac_12369	1.157e-21	107.0	2E295@1|root,32XEV@2|Bacteria	2|Bacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD3_k127_1454804_0	204669.Acid345_2257	2.837e-58	207.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GZD3_k127_1454804_1	316274.Haur_2162	1.119e-54	205.0	COG1427@1|root,COG1427@2|Bacteria	2|Bacteria	E	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	1.21.98.1,4.2.1.151	ko:K07081,ko:K11782,ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588,R10666	RC02329,RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GZD3_k127_1454804_2	1128421.JAGA01000003_gene2742	3.926e-54	201.0	COG1309@1|root,COG1309@2|Bacteria,2NRTD@2323|unclassified Bacteria	2|Bacteria	K	YsiA-like protein, C-terminal region	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TetR_C_4,TetR_N
GZD3_k127_1454804_4	179408.Osc7112_2482	1.101e-11	72.0	2DN4E@1|root,32VGA@2|Bacteria,1G7ZM@1117|Cyanobacteria,1HCGT@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1454804_3	521011.Mpal_1114	4.914e-26	108.0	COG5361@1|root,arCOG05285@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1254
GZD3_k127_1492711_0	1382356.JQMP01000001_gene750	3.207e-314	975.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD3_k127_1492711_4	1128421.JAGA01000001_gene2230	9.488e-173	561.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K03520,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
GZD3_k127_1492711_1	485913.Krac_9369	4.642e-276	860.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_1492711_2	485913.Krac_9370	1.08e-258	809.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_1492711_3	1128421.JAGA01000001_gene2231	2.164e-188	600.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	allB	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GZD3_k127_150282_3	485913.Krac_4354	1.042e-37	144.0	COG3189@1|root,COG3189@2|Bacteria,2G90C@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
GZD3_k127_150282_0	211165.AJLN01000061_gene4018	3.287e-246	771.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JHD5@1189|Stigonemataceae	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
GZD3_k127_150282_2	926560.KE387023_gene1700	1.009e-172	554.0	COG3437@1|root,COG3852@1|root,COG3437@2|Bacteria,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	2|Bacteria	T	Histidine kinase-like ATPases	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K17763	ko00230,ko02020,ko02025,ko04112,ko04113,ko04213,map00230,map02020,map02025,map04112,map04113,map04213	M00511,M00695	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	GGDEF,HATPase_c,HisKA,HisKA_3,PAS,PAS_9,Response_reg,cNMP_binding
GZD3_k127_150282_1	926560.KE387023_gene1701	2.56e-195	626.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD3_k127_1513024_1	1382306.JNIM01000001_gene2528	1.605e-67	243.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GZD3_k127_1513024_2	485913.Krac_6398	1.951e-35	143.0	COG0537@1|root,COG0537@2|Bacteria,2G6VV@200795|Chloroflexi	200795|Chloroflexi	FG	PFAM histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
GZD3_k127_1513024_0	1382306.JNIM01000001_gene3498	1.794e-161	528.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
GZD3_k127_1513024_3	1121405.dsmv_0102	2.554e-09	60.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2MJIU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GZD3_k127_1518031_0	1128421.JAGA01000003_gene2944	3.438e-156	503.0	COG1640@1|root,COG1640@2|Bacteria,2NP2W@2323|unclassified Bacteria	2|Bacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	iJN678.malQ	Glyco_hydro_77
GZD3_k127_1518031_1	767817.Desgi_1716	6.548e-94	316.0	COG0438@1|root,COG0438@2|Bacteria,1TS4X@1239|Firmicutes,24BYU@186801|Clostridia,261FH@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GZD3_k127_1521976_1	479434.Sthe_3430	7.809e-56	204.0	COG1680@1|root,COG1680@2|Bacteria,2G6QM@200795|Chloroflexi,27XFJ@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GZD3_k127_1521976_0	756883.Halar_0591	4.554e-58	211.0	arCOG08204@1|root,arCOG08204@2157|Archaea	2157|Archaea	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
GZD3_k127_152438_11	879212.DespoDRAFT_01191	4.895e-31	143.0	28HHI@1|root,2Z7T8@2|Bacteria,1NQM7@1224|Proteobacteria,430MZ@68525|delta/epsilon subdivisions,2WVUP@28221|Deltaproteobacteria,2MNNP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_152438_9	879212.DespoDRAFT_01189	1.89e-45	181.0	28KYK@1|root,2ZAE4@2|Bacteria,1NRH4@1224|Proteobacteria,430WV@68525|delta/epsilon subdivisions,2WVUD@28221|Deltaproteobacteria,2MNRT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_152438_1	879212.DespoDRAFT_01188	4.387e-194	620.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,42RE9@68525|delta/epsilon subdivisions,2WNSX@28221|Deltaproteobacteria,2MM13@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
GZD3_k127_152438_13	1121423.JONT01000022_gene79	4.792e-06	57.0	2CA80@1|root,2Z845@2|Bacteria,1UXYY@1239|Firmicutes,24FKF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_152438_14	272134.KB731325_gene542	0.0001207	47.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
GZD3_k127_152438_5	521098.Aaci_2281	4.194e-110	368.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli	91061|Bacilli	K	Transcriptional	rbsR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
GZD3_k127_152438_10	1111479.AXAR01000001_gene119	2.972e-39	149.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli	91061|Bacilli	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
GZD3_k127_152438_2	646529.Desaci_2773	3.367e-163	532.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,260WP@186807|Peptococcaceae	186801|Clostridia	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
GZD3_k127_152438_4	1120971.AUCA01000024_gene467	3.556e-125	411.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
GZD3_k127_152438_3	646529.Desaci_2771	4.263e-131	428.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
GZD3_k127_152438_8	1382304.JNIL01000001_gene2792	5.919e-68	245.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli	91061|Bacilli	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GZD3_k127_152438_7	1382306.JNIM01000001_gene725	7.883e-84	287.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GZD3_k127_152438_12	1095767.CAHD01000013_gene935	2.961e-09	66.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria	201174|Actinobacteria	T	Phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
GZD3_k127_152438_6	479432.Sros_3295	8.539e-88	298.0	COG0684@1|root,COG0684@2|Bacteria,2I9PH@201174|Actinobacteria	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
GZD3_k127_152438_0	1386089.N865_16085	4.358e-213	666.0	COG0477@1|root,COG2814@2|Bacteria,2I3MJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
GZD3_k127_1524488_2	1121451.DESAM_23244	2.16e-38	151.0	COG0659@1|root,COG0659@2|Bacteria,1MX1U@1224|Proteobacteria,42Q8Y@68525|delta/epsilon subdivisions,2WK07@28221|Deltaproteobacteria,2M9WF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
GZD3_k127_1524488_0	926569.ANT_19830	4.027e-109	365.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GZD3_k127_1524488_1	926569.ANT_22470	7.749e-53	195.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GZD3_k127_1524488_3	584708.Apau_0556	1.261e-19	89.0	COG1533@1|root,COG1533@2|Bacteria,3TBCX@508458|Synergistetes	508458|Synergistetes	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GZD3_k127_1528520_2	1348663.KCH_72460	1.2e-41	162.0	COG1881@1|root,COG1881@2|Bacteria,2IIR9@201174|Actinobacteria,2M2TX@2063|Kitasatospora	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GZD3_k127_1528520_1	1323361.JPOC01000013_gene3775	1.724e-74	268.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4G9I9@85025|Nocardiaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD3_k127_1528520_0	485913.Krac_10294	9.127e-105	354.0	COG1160@1|root,COG3597@1|root,COG1160@2|Bacteria,COG3597@2|Bacteria,2G9CM@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
GZD3_k127_1528520_3	643473.KB235930_gene2294	1.992e-14	75.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD3_k127_1531318_9	1349820.M707_09175	8.203e-06	51.0	COG0716@1|root,COG3467@1|root,COG0716@2|Bacteria,COG3467@2|Bacteria,2IQZD@201174|Actinobacteria	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
GZD3_k127_1531318_2	1174528.JH992892_gene6574	1.292e-63	227.0	COG2823@1|root,COG2823@2|Bacteria,1GCMH@1117|Cyanobacteria	1117|Cyanobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_1531318_10	1123386.AUIW01000009_gene1739	2.439e-05	51.0	COG3462@1|root,COG3462@2|Bacteria,1WKPU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	-
GZD3_k127_1531318_8	330214.NIDE3924	5.505e-06	56.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
GZD3_k127_1531318_1	485913.Krac_2195	9.655e-83	299.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX,Rieske
GZD3_k127_1531318_3	1194972.MVAC_28144	3.867e-55	203.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,233IU@1762|Mycobacteriaceae	201174|Actinobacteria	K	Member of the two-component regulatory system MprB MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_1531318_4	498761.HM1_1536	1.845e-47	191.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,249CD@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GZD3_k127_1531318_5	1051632.TPY_3048	1.577e-25	114.0	arCOG07408@1|root,2ZWPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1531318_0	926550.CLDAP_00380	9.676e-145	471.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GZD3_k127_1533746_0	525904.Tter_2339	5.229e-130	430.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
GZD3_k127_1533746_1	877455.Metbo_0186	4.445e-71	259.0	COG2239@1|root,arCOG00634@2157|Archaea,2XWIB@28890|Euryarchaeota,23PEC@183925|Methanobacteria	183925|Methanobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
GZD3_k127_153772_3	383372.Rcas_3377	5.444e-82	278.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,3780S@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_153772_14	1267535.KB906767_gene237	2.766e-13	79.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_153772_1	1242864.D187_000285	4.087e-121	393.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42NZ6@68525|delta/epsilon subdivisions,2WKPZ@28221|Deltaproteobacteria,2YWD6@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GZD3_k127_153772_2	1242864.D187_004101	5.103e-86	298.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
GZD3_k127_153772_4	485913.Krac_10748	5.916e-61	226.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2,Peptidase_M22
GZD3_k127_153772_16	216816.GS08_02650	3.477e-11	74.0	COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales	201174|Actinobacteria	D	CHAP domain protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP
GZD3_k127_153772_10	797304.Natgr_1845	1.221e-33	151.0	COG5410@1|root,arCOG09550@2157|Archaea,2XVK5@28890|Euryarchaeota,23UYZ@183963|Halobacteria	183963|Halobacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
GZD3_k127_153772_12	1141106.CAIB01000133_gene1117	1.196e-31	133.0	2EVUX@1|root,33P8N@2|Bacteria,1VUVM@1239|Firmicutes	1239|Firmicutes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
GZD3_k127_153772_0	1382306.JNIM01000001_gene3861	1.628e-158	526.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GZD3_k127_153772_5	1382306.JNIM01000001_gene2535	1.781e-57	205.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GZD3_k127_153772_7	479434.Sthe_2734	6.431e-43	166.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
GZD3_k127_153772_11	710686.Mycsm_04737	1.317e-32	142.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,2366T@1762|Mycobacteriaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
GZD3_k127_153772_9	1380390.JIAT01000010_gene4861	3.149e-36	143.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4CQN1@84995|Rubrobacteria	84995|Rubrobacteria	M	Large-conductance mechanosensitive channel, MscL	-	-	-	-	-	-	-	-	-	-	-	-	MscL
GZD3_k127_153772_8	485913.Krac_4389	6.916e-37	143.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K05558,ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
GZD3_k127_153772_13	1382306.JNIM01000001_gene925	1.782e-16	83.0	2E3KN@1|root,32YIY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
GZD3_k127_153772_6	266117.Rxyl_2946	3.309e-45	179.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GZD3_k127_1540284_4	1121904.ARBP01000032_gene2006	4.238e-45	175.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
GZD3_k127_1540284_2	309801.trd_A0525	8.114e-51	198.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GZD3_k127_1540284_1	1382306.JNIM01000001_gene2820	1.373e-73	256.0	COG2453@1|root,COG2453@2|Bacteria,2G7AB@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Dual specificity protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
GZD3_k127_1540284_0	1382306.JNIM01000001_gene2821	5.176e-99	333.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
GZD3_k127_1540284_5	1041930.Mtc_0426	4.536e-44	177.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8C9@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_1540284_3	660470.Theba_2484	8.97e-46	189.0	COG1874@1|root,COG1874@2|Bacteria,2GE0T@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 35 family	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
GZD3_k127_1547036_4	485913.Krac_8725	6.064e-43	162.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
GZD3_k127_1547036_3	485913.Krac_12607	4.871e-56	200.0	COG2050@1|root,COG2050@2|Bacteria,2G9RF@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_1547036_7	58344.JOEL01000025_gene689	1.735e-24	113.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_6,Acetyltransf_7,Acetyltransf_9
GZD3_k127_1547036_2	926550.CLDAP_06280	2.255e-131	428.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_1547036_5	1234664.AMRO01000027_gene1215	5.591e-42	160.0	2AFVE@1|root,315XY@2|Bacteria,1V9WC@1239|Firmicutes,4HJ2Y@91061|Bacilli,1WHEF@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1547036_1	309801.trd_A0629	1.004e-154	504.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
GZD3_k127_1547036_6	1278073.MYSTI_01384	3.887e-37	145.0	COG0317@1|root,COG0317@2|Bacteria,1N2BZ@1224|Proteobacteria,430HK@68525|delta/epsilon subdivisions,2WVNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
GZD3_k127_1547036_0	309801.trd_A0628	0.0	1416.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
GZD3_k127_1565011_0	99598.Cal7507_2942	9.136e-83	282.0	COG0436@1|root,COG0436@2|Bacteria,1G2TF@1117|Cyanobacteria,1HJDX@1161|Nostocales	1117|Cyanobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD3_k127_156807_0	1382306.JNIM01000001_gene2312	7.22e-122	406.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
GZD3_k127_1569041_0	215803.DB30_2841	4.576e-177	571.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD3_k127_1581032_0	485913.Krac_11960	3.68e-107	361.0	COG0477@1|root,COG2814@2|Bacteria,2G77Q@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_1584930_0	926569.ANT_14270	1.619e-109	362.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD3_k127_1584930_1	351607.Acel_0588	5.897e-105	361.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4EUGM@85013|Frankiales	201174|Actinobacteria	C	PFAM catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD3_k127_1584930_2	485913.Krac_11273	2.176e-52	201.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
GZD3_k127_1584930_3	251221.35211248	5.071e-42	158.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_1584930_4	1254432.SCE1572_13735	6.066e-26	116.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.180	ko:K18846	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_1586806_0	479434.Sthe_0485	3.991e-104	373.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
GZD3_k127_1590550_0	1382306.JNIM01000001_gene3911	2.534e-127	417.0	COG0466@1|root,COG0466@2|Bacteria,2G7KC@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD3_k127_1595966_5	1121930.AQXG01000008_gene184	4.109e-79	266.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
GZD3_k127_1595966_1	485913.Krac_3643	4.286e-182	577.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi	200795|Chloroflexi	C	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GZD3_k127_1595966_0	1382306.JNIM01000001_gene3362	8.94e-193	608.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GZD3_k127_1595966_6	326427.Cagg_3772	1.44e-50	206.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
GZD3_k127_1595966_4	485913.Krac_8846	7.687e-94	344.0	COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
GZD3_k127_1595966_7	585.DR95_2385	4.514e-34	141.0	COG4245@1|root,COG4245@2|Bacteria,1MVUE@1224|Proteobacteria,1RQ4Q@1236|Gammaproteobacteria,3Z3FH@583|Proteus	1236|Gammaproteobacteria	S	von willebrand factor, type A	terY	-	-	-	-	-	-	-	-	-	-	-	VWA
GZD3_k127_1595966_3	285514.JNWO01000006_gene1683	1.358e-94	322.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GZD3_k127_1595966_2	463191.SSEG_06319	4.402e-109	359.0	COG0022@1|root,COG0508@1|root,COG0022@2|Bacteria,COG0508@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	bkdB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD3_k127_1599382_1	562970.Btus_1652	1.532e-79	276.0	COG2181@1|root,COG2181@2|Bacteria,1UY97@1239|Firmicutes,4HD9W@91061|Bacilli,2796M@186823|Alicyclobacillaceae	91061|Bacilli	C	Nitrate reductase gamma subunit	narI	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
GZD3_k127_1599382_0	1382306.JNIM01000001_gene3489	4.396e-114	371.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
GZD3_k127_1602132_0	266117.Rxyl_0618	5.082e-196	624.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CPJQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GZD3_k127_1602132_4	485913.Krac_5056	1.268e-05	56.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP,GBS_Bsp-like
GZD3_k127_1602132_2	1461580.CCAS010000103_gene4512	1.261e-125	411.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,1ZDYJ@1386|Bacillus	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GZD3_k127_1602132_3	1501230.ET33_00170	1.936e-44	169.0	COG1846@1|root,COG1846@2|Bacteria,1V4SH@1239|Firmicutes,4IR3K@91061|Bacilli,276MP@186822|Paenibacillaceae	91061|Bacilli	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GZD3_k127_1602132_1	1382306.JNIM01000001_gene412	1.14e-133	434.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GZD3_k127_1616519_3	479434.Sthe_2211	9.574e-97	323.0	COG0491@1|root,COG0491@2|Bacteria,2G846@200795|Chloroflexi,27YRW@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1616519_0	1382306.JNIM01000001_gene1415	2.736e-170	550.0	COG1653@1|root,COG1653@2|Bacteria,2G8AR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
GZD3_k127_1616519_2	1382306.JNIM01000001_gene1416	2.265e-124	410.0	COG1175@1|root,COG1175@2|Bacteria,2G7P7@200795|Chloroflexi	200795|Chloroflexi	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
GZD3_k127_1616519_1	1382306.JNIM01000001_gene1417	9.852e-136	453.0	COG0395@1|root,COG0395@2|Bacteria,2G82A@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
GZD3_k127_1616519_9	331678.Cphamn1_1941	1.087e-14	75.0	2E46S@1|root,32Z2Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1616519_8	485913.Krac_12368	4.286e-15	78.0	2EP0Z@1|root,33GMU@2|Bacteria	2|Bacteria	K	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GZD3_k127_1616519_11	446466.Cfla_2214	5.354e-06	55.0	COG3296@1|root,COG3296@2|Bacteria,2IQSV@201174|Actinobacteria,4F1HK@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
GZD3_k127_1616519_4	485913.Krac_10139	7.513e-93	318.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_1616519_10	40149.OMERI01G19420.1	2.068e-08	66.0	COG0484@1|root,KOG0714@2759|Eukaryota,37VWD@33090|Viridiplantae,3GIK3@35493|Streptophyta,3KZ69@4447|Liliopsida,3IGWD@38820|Poales	35493|Streptophyta	O	DnaJ domain	-	-	-	ko:K09514	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ
GZD3_k127_1616519_7	485913.Krac_5990	5.999e-28	128.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi	200795|Chloroflexi	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
GZD3_k127_1616519_6	1150864.MILUP08_41306	1.792e-32	128.0	2B1D5@1|root,31TTS@2|Bacteria,2GSZW@201174|Actinobacteria,4DJGA@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1616519_5	35754.JNYJ01000055_gene9994	6.268e-33	132.0	COG0662@1|root,COG0662@2|Bacteria,2II1B@201174|Actinobacteria,4DDJ1@85008|Micromonosporales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_1619299_9	1382306.JNIM01000001_gene771	0.0004217	42.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
GZD3_k127_1619299_5	309801.trd_1490	1.808e-22	105.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_1619299_0	485913.Krac_11730	5.929e-178	573.0	COG4187@1|root,COG4187@2|Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	rocB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
GZD3_k127_1619299_1	1382306.JNIM01000001_gene1117	9.666e-126	413.0	COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
GZD3_k127_1619299_7	485913.Krac_6589	5.324e-09	64.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_1619299_2	1382306.JNIM01000001_gene3367	2.931e-57	222.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GZD3_k127_1619299_3	1437824.BN940_09791	6.442e-45	171.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,3T49M@506|Alcaligenaceae	28216|Betaproteobacteria	E	Lactoylglutathione lyase	gloA3	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_1619299_6	67352.JODS01000046_gene3590	1.824e-21	105.0	COG0500@1|root,COG2226@2|Bacteria,2H1GK@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_1619299_8	1122223.KB890697_gene1208	9.125e-07	58.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_1619299_4	670487.Ocepr_1853	9.743e-45	173.0	COG0500@1|root,COG2226@2|Bacteria,1WJAK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_1619498_1	1382306.JNIM01000001_gene886	1.568e-86	293.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
GZD3_k127_1619498_0	485913.Krac_11296	6.2e-94	321.0	COG0665@1|root,COG0665@2|Bacteria,2G80C@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GZD3_k127_1619498_2	927677.ALVU02000008_gene54	1.689e-16	85.0	COG4113@1|root,COG4113@2|Bacteria,1G6X3@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GZD3_k127_1625403_6	1296416.JACB01000035_gene2965	1.928e-08	60.0	2A2X1@1|root,30RB8@2|Bacteria,4PH4D@976|Bacteroidetes,1IMBT@117743|Flavobacteriia,2YJS9@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1625403_3	1382306.JNIM01000001_gene2529	9.785e-107	379.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1625403_2	1382306.JNIM01000001_gene2530	6.659e-110	361.0	COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_1625403_1	1128421.JAGA01000002_gene786	6.909e-115	378.0	COG0024@1|root,COG0024@2|Bacteria,2NP57@2323|unclassified Bacteria	2|Bacteria	J	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
GZD3_k127_1625403_0	1382306.JNIM01000001_gene1323	0.0	1072.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
GZD3_k127_1625403_4	479434.Sthe_1775	9.076e-86	293.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_1625403_5	383372.Rcas_4144	5.438e-50	196.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,376EU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
GZD3_k127_1638153_2	1157490.EL26_20285	4.049e-17	83.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,278MZ@186823|Alicyclobacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
GZD3_k127_1638153_1	1120973.AQXL01000109_gene1921	2.503e-86	291.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,2784H@186823|Alicyclobacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
GZD3_k127_1638153_0	1111479.AXAR01000009_gene2528	1.092e-135	443.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,2783J@186823|Alicyclobacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GZD3_k127_1652447_4	1526927.Plano_1103	3.934e-20	94.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,26CVY@186818|Planococcaceae	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD3_k127_1652447_1	1382306.JNIM01000001_gene914	3.079e-107	362.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
GZD3_k127_1652447_3	485913.Krac_6878	2.347e-36	145.0	2EQ8R@1|root,33HV0@2|Bacteria,2G91J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1652447_0	1089553.Tph_c04670	2.897e-256	818.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD3_k127_1652447_2	485913.Krac_10552	3.671e-43	173.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1652583_1	316274.Haur_0099	1.225e-34	154.0	COG3372@1|root,COG3372@2|Bacteria,2G9BS@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
GZD3_k127_1652583_0	1128421.JAGA01000003_gene2963	9.706e-78	265.0	COG1061@1|root,COG1061@2|Bacteria,2NRQG@2323|unclassified Bacteria	2|Bacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
GZD3_k127_16552_3	234267.Acid_3693	8.849e-48	179.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GZD3_k127_16552_0	485913.Krac_8969	2.899e-113	386.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_16552_2	1521187.JPIM01000026_gene1160	2.706e-57	221.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GZD3_k127_16552_1	485913.Krac_6859	2.466e-101	337.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GZD3_k127_166384_1	1454004.AW11_02083	4.852e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2WF0A@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GZD3_k127_166384_0	525904.Tter_2117	2.251e-97	333.0	COG1252@1|root,COG1252@2|Bacteria,2NP3T@2323|unclassified Bacteria	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD3_k127_1681391_0	1394178.AWOO02000054_gene8006	7.787e-90	312.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4EPD8@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_1681391_7	1235813.JCM10003_3133	8.087e-05	49.0	COG2261@1|root,COG2261@2|Bacteria,4NUXX@976|Bacteroidetes,2FUM7@200643|Bacteroidia,4ARQR@815|Bacteroidaceae	976|Bacteroidetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD3_k127_1681391_1	485913.Krac_0786	1.036e-55	225.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_1681391_4	580331.Thit_0907	2.164e-28	135.0	COG5650@1|root,COG5650@2|Bacteria,1TQVD@1239|Firmicutes,25CFN@186801|Clostridia,42F5W@68295|Thermoanaerobacterales	186801|Clostridia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2
GZD3_k127_1681391_3	1280390.CBQR020000092_gene1970	1.643e-28	135.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4HNW3@91061|Bacilli,27548@186822|Paenibacillaceae	91061|Bacilli	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2,PMT_4TMC
GZD3_k127_1681391_5	485913.Krac_11174	2.855e-28	130.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
GZD3_k127_1681391_2	1382306.JNIM01000001_gene1439	2.172e-33	149.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
GZD3_k127_1681391_6	1386089.N865_11555	8.917e-07	60.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
GZD3_k127_1681391_8	34349.G7DSW9	0.0006137	50.0	2EDEZ@1|root,2SJ2P@2759|Eukaryota,39ZQW@33154|Opisthokonta,3P04N@4751|Fungi,3VBID@5204|Basidiomycota	4751|Fungi	G	bnr asp-box repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GZD3_k127_1685_0	485913.Krac_3101	2.409e-106	352.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
GZD3_k127_1685_1	1347086.CCBA010000011_gene1621	5.866e-63	224.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,4IR38@91061|Bacilli,1ZFX1@1386|Bacillus	91061|Bacilli	F	Phosphoribulokinase / Uridine kinase family	-	-	-	-	-	-	-	-	-	-	-	-	PRK
GZD3_k127_1685_3	485913.Krac_12156	5.759e-47	174.0	COG1162@1|root,COG1162@2|Bacteria	2|Bacteria	S	GTPase activity	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RNHCP,RsgA_GTPase
GZD3_k127_1685_2	485913.Krac_12010	1.806e-53	197.0	COG1385@1|root,COG1385@2|Bacteria,2G70G@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
GZD3_k127_1685412_1	338966.Ppro_3581	1.637e-90	300.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GZD3_k127_1685412_2	370438.PTH_0785	5.127e-90	314.0	COG1113@1|root,COG1113@2|Bacteria,1UJS3@1239|Firmicutes,24F0Q@186801|Clostridia,2616D@186807|Peptococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD3_k127_1685412_12	335541.Swol_0838	0.0003605	50.0	COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,249A1@186801|Clostridia	186801|Clostridia	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_1685412_6	1173028.ANKO01000159_gene5171	2.494e-49	183.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1G0P8@1117|Cyanobacteria,1H7DA@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_1685412_7	485913.Krac_3181	7.061e-42	159.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
GZD3_k127_1685412_3	68260.JOAY01000015_gene2693	2.743e-86	321.0	2B756@1|root,3206P@2|Bacteria,2H3NN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1685412_10	1463841.JOIR01000026_gene261	3.9e-23	109.0	2B6ZW@1|root,32008@2|Bacteria,2H37C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1685412_8	1128421.JAGA01000002_gene1598	1.387e-35	155.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_1685412_5	1382356.JQMP01000003_gene1742	5.555e-55	197.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_1685412_0	485913.Krac_10266	1.834e-95	324.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M55
GZD3_k127_1685412_9	639030.JHVA01000001_gene536	2.713e-25	112.0	COG3411@1|root,COG3411@2|Bacteria,3Y54Q@57723|Acidobacteria,2JJSF@204432|Acidobacteriia	204432|Acidobacteriia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1685412_4	68223.JNZY01000052_gene358	6.255e-56	214.0	COG0477@1|root,COG2814@2|Bacteria,2ID9K@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_1696474_0	1382306.JNIM01000001_gene4094	2.175e-76	268.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
GZD3_k127_1696474_1	1382306.JNIM01000001_gene2680	4.565e-11	68.0	COG0720@1|root,COG0720@2|Bacteria,2G919@200795|Chloroflexi	200795|Chloroflexi	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GZD3_k127_1723495_1	485913.Krac_7619	1.641e-41	157.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GZD3_k127_1723495_0	485913.Krac_9225	6.909e-70	245.0	COG0406@1|root,COG0406@2|Bacteria,2G72Q@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
GZD3_k127_1723495_2	485913.Krac_12067	5.94e-21	95.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
GZD3_k127_1753888_8	485913.Krac_8415	5.236e-52	188.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
GZD3_k127_1753888_2	1382306.JNIM01000001_gene1757	8.129e-107	354.0	COG0208@1|root,COG0208@2|Bacteria,2G610@200795|Chloroflexi	200795|Chloroflexi	F	PFAM ribonucleotide reductase	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
GZD3_k127_1753888_5	1382306.JNIM01000001_gene2845	5.452e-78	283.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
GZD3_k127_1753888_12	4529.ORUFI02G35180.1	1.079e-07	64.0	28NGJ@1|root,2QV26@2759|Eukaryota,37PB2@33090|Viridiplantae,3GKQC@35493|Streptophyta,3M5JU@4447|Liliopsida,3IHIU@38820|Poales	35493|Streptophyta	K	AP2 domain	-	-	-	-	-	-	-	-	-	-	-	-	AP2
GZD3_k127_1753888_11	1274524.BSONL12_04374	2.057e-15	89.0	2E2AR@1|root,32XG5@2|Bacteria,1VHHN@1239|Firmicutes	1239|Firmicutes	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP2,HNH_3
GZD3_k127_1753888_9	326427.Cagg_3499	6.126e-46	177.0	COG4420@1|root,COG4420@2|Bacteria,2GAPG@200795|Chloroflexi,376QD@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
GZD3_k127_1753888_7	1451261.AS96_00370	3.846e-55	219.0	COG1215@1|root,COG1215@2|Bacteria,2GNYT@201174|Actinobacteria,4FRPM@85023|Microbacteriaceae	201174|Actinobacteria	M	GtrA-like protein	dpm	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
GZD3_k127_1753888_0	1382306.JNIM01000001_gene1046	1.508e-122	404.0	COG4585@1|root,COG4585@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
GZD3_k127_1753888_1	485913.Krac_6669	5.599e-109	357.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_1753888_10	485913.Krac_6670	7.066e-33	135.0	2CJPB@1|root,33JM7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1753888_6	1382306.JNIM01000001_gene2816	5.072e-73	266.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_1753888_4	485913.Krac_2053	2.367e-100	344.0	COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GZD3_k127_1753888_3	1382306.JNIM01000001_gene751	9.333e-105	345.0	COG0745@1|root,COG0745@2|Bacteria,2G6H6@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_1756371_0	926569.ANT_23450	7.928e-160	511.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
GZD3_k127_1756371_1	926569.ANT_23460	1.452e-43	162.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
GZD3_k127_1769536_2	765420.OSCT_2281	5.375e-38	160.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GZD3_k127_1769536_1	1237500.ANBA01000001_gene5051	9.977e-42	163.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria,4EN67@85012|Streptosporangiales	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TPMT
GZD3_k127_1769536_0	269799.Gmet_3082	7.456e-142	461.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2X6YF@28221|Deltaproteobacteria,43TQ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
GZD3_k127_1785303_1	1128421.JAGA01000003_gene2795	3.112e-88	302.0	COG0324@1|root,COG0324@2|Bacteria,2NP6D@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
GZD3_k127_1785303_4	485913.Krac_4790	1.221e-65	233.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GZD3_k127_1785303_3	1382306.JNIM01000001_gene4128	1.066e-78	291.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
GZD3_k127_1785303_5	552811.Dehly_0509	2.794e-24	109.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
GZD3_k127_1785303_2	485913.Krac_11106	4.624e-81	278.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_1785303_7	309801.trd_1051	0.0001166	53.0	COG5662@1|root,COG5662@2|Bacteria,2GBGZ@200795|Chloroflexi,27XXW@189775|Thermomicrobia	189775|Thermomicrobia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GZD3_k127_1785303_0	1476583.DEIPH_ctg020orf0011	1.504e-123	407.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD3_k127_1785303_6	1382306.JNIM01000001_gene4110	2.695e-21	93.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GZD3_k127_1787094_1	266117.Rxyl_0958	1.637e-111	371.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CPHB@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
GZD3_k127_1787094_2	479434.Sthe_2501	2.167e-37	145.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD3_k127_1787094_0	1382306.JNIM01000001_gene3578	1.216e-132	430.0	COG2141@1|root,COG2141@2|Bacteria,2G6CZ@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_1787094_3	1227352.C173_13127	7.459e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,1VB3P@1239|Firmicutes,4HMZV@91061|Bacilli,26XJ8@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	ycdB	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF4901,Sigma70_r2,Sigma70_r4_2
GZD3_k127_1787094_4	68194.JNXR01000016_gene7274	9.255e-05	51.0	COG2197@1|root,COG2197@2|Bacteria,2H94E@201174|Actinobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GZD3_k127_1792648_2	312284.A20C1_12039	4.047e-19	97.0	COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria	201174|Actinobacteria	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GZD3_k127_1792648_0	525904.Tter_1772	2.284e-33	133.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
GZD3_k127_1807180_1	765420.OSCT_1961	1.065e-66	233.0	COG1279@1|root,COG1279@2|Bacteria	2|Bacteria	S	arginine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
GZD3_k127_1807180_4	287986.DV20_14205	6.835e-29	122.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
GZD3_k127_1807180_6	1121946.AUAX01000002_gene182	2.966e-08	57.0	COG3340@1|root,COG3340@2|Bacteria,2GMIV@201174|Actinobacteria,4D9N5@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD3_k127_1807180_3	485913.Krac_3813	2.402e-43	163.0	COG3340@1|root,COG3340@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD3_k127_1807180_2	285514.JNWO01000006_gene1687	1.259e-45	182.0	COG1063@1|root,COG1940@1|root,COG1063@2|Bacteria,COG1940@2|Bacteria,2I4CD@201174|Actinobacteria	201174|Actinobacteria	GK	transcriptional regulator sugar kinase	-	-	2.7.1.188	ko:K19979	ko00525,ko01130,map00525,map01130	M00814	R11185	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ROK
GZD3_k127_1807180_5	316274.Haur_4171	1.814e-09	62.0	COG4283@1|root,COG4283@2|Bacteria,2G9ST@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD3_k127_1823444_1	1382306.JNIM01000001_gene3958	4.89e-73	262.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
GZD3_k127_1823444_2	1382306.JNIM01000001_gene3959	6.849e-70	244.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GZD3_k127_1823444_0	926560.KE387023_gene2636	1.139e-279	887.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1WIM7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
GZD3_k127_1823444_3	485913.Krac_8441	7.525e-39	152.0	COG0640@1|root,COG0640@2|Bacteria,2G9JF@200795|Chloroflexi	200795|Chloroflexi	K	SMART regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GZD3_k127_1833802_0	485913.Krac_10921	9.955e-119	405.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi	200795|Chloroflexi	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
GZD3_k127_1843894_2	927677.ALVU02000001_gene4704	2.94e-107	357.0	COG1131@1|root,COG1131@2|Bacteria,1G3BQ@1117|Cyanobacteria,1H4K5@1142|Synechocystis	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD3_k127_1843894_1	383372.Rcas_2712	4.637e-142	460.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,376Y0@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GZD3_k127_1843894_5	485913.Krac_10313	7.443e-77	269.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD3_k127_1843894_4	500153.JOEK01000009_gene5062	2.365e-79	273.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_1843894_7	75379.Tint_2048	2.314e-33	136.0	COG4319@1|root,COG4319@2|Bacteria,1N0SJ@1224|Proteobacteria,2W47Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
GZD3_k127_1843894_0	518766.Rmar_1222	2.944e-192	626.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1FJ26@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
GZD3_k127_1843894_6	383372.Rcas_3064	1.091e-53	206.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD3_k127_1843894_3	479434.Sthe_2390	7.928e-105	351.0	COG2378@1|root,COG2378@2|Bacteria,2G7SN@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Helix-turn-helix, type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
GZD3_k127_1844295_0	1265310.CCBD010000070_gene30	7.535e-146	479.0	COG2041@1|root,COG4117@1|root,COG2041@2|Bacteria,COG4117@2|Bacteria,2GIZH@201174|Actinobacteria,235GI@1762|Mycobacteriaceae	201174|Actinobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
GZD3_k127_1844295_1	1382306.JNIM01000001_gene19	1.277e-59	212.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
GZD3_k127_1854926_4	869210.Marky_0312	6.289e-05	46.0	COG0346@1|root,COG0346@2|Bacteria,1WMVF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_1854926_0	1382306.JNIM01000001_gene1523	1.925e-97	326.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
GZD3_k127_1854926_1	383372.Rcas_4356	1.303e-54	220.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_1854926_2	1382306.JNIM01000001_gene400	4.51e-45	181.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
GZD3_k127_1854926_3	314285.KT71_14579	6.465e-23	103.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1JACF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Translation initiation factor SUI1	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
GZD3_k127_186312_5	1464048.JNZS01000007_gene4600	1.908e-15	78.0	COG0748@1|root,COG0748@2|Bacteria,2I2TX@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
GZD3_k127_186312_2	391625.PPSIR1_15530	1.374e-52	191.0	KOG4143@1|root,344U3@2|Bacteria	2|Bacteria	O	ERG2 and Sigma1 receptor like protein	-	-	-	ko:K20719	-	-	-	-	ko00000,ko02000	8.A.63.1.1	-	-	ERG2_Sigma1R
GZD3_k127_186312_0	1382306.JNIM01000001_gene2684	1.749e-124	407.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10
GZD3_k127_186312_3	697303.Thewi_2044	3.092e-51	195.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
GZD3_k127_186312_4	398527.Bphyt_5729	5.329e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,1R004@1224|Proteobacteria,2WHR5@28216|Betaproteobacteria,1KAN5@119060|Burkholderiaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_186312_6	411467.BACCAP_00219	0.0007891	51.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,268TI@186813|unclassified Clostridiales	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
GZD3_k127_186312_1	525904.Tter_0551	1.373e-108	367.0	COG3294@1|root,COG3294@2|Bacteria,2NR9E@2323|unclassified Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
GZD3_k127_1875664_3	485913.Krac_10552	6.82e-41	156.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1875664_8	1122138.AQUZ01000009_gene3973	4.14e-07	58.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria,4DSRB@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD3_k127_1875664_4	324602.Caur_2188	2.978e-34	136.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,375VM@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
GZD3_k127_1875664_5	1382306.JNIM01000001_gene91	6.684e-33	138.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
GZD3_k127_1875664_0	485913.Krac_9208	2.401e-104	344.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
GZD3_k127_1875664_2	243164.DET0993	9.503e-64	222.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi,34DBF@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
GZD3_k127_1875664_1	1382306.JNIM01000001_gene88	4.219e-77	266.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
GZD3_k127_1875664_6	485913.Krac_9204	2.78e-19	89.0	COG0267@1|root,COG0267@2|Bacteria,2G7GT@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
GZD3_k127_1875664_7	243090.RB7894	1.253e-13	70.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GZD3_k127_188502_1	926569.ANT_24910	3.383e-135	441.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD3_k127_188502_0	67315.JOBD01000001_gene1124	2.729e-179	571.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
GZD3_k127_1892285_0	485913.Krac_2635	2.126e-295	938.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
GZD3_k127_1892285_8	485913.Krac_2634	8.25e-62	231.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS
GZD3_k127_1892285_3	485913.Krac_6992	4.559e-90	315.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1892285_9	485913.Krac_6021	1.33e-53	205.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1892285_7	485913.Krac_6021	2.333e-67	244.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1892285_6	485913.Krac_10552	1.487e-68	248.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1892285_2	485913.Krac_2641	1.508e-189	606.0	COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi	200795|Chloroflexi	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GZD3_k127_1892285_11	485913.Krac_2639	2.318e-33	133.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD3_k127_1892285_10	485913.Krac_2638	1.516e-41	156.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
GZD3_k127_1892285_1	485913.Krac_2637	8.038e-204	651.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
GZD3_k127_1908299_8	1449347.JQLN01000005_gene4518	5.648e-30	120.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,2M0D5@2063|Kitasatospora	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD3_k127_1908299_1	1123024.AUII01000029_gene4044	1.309e-85	301.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4DXDX@85010|Pseudonocardiales	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD3_k127_1908299_6	326427.Cagg_0125	8.511e-45	179.0	COG2270@1|root,COG2270@2|Bacteria,2G6G1@200795|Chloroflexi,375K4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_1908299_3	485913.Krac_6400	1.738e-65	236.0	COG0500@1|root,COG2226@2|Bacteria,2G9SY@200795|Chloroflexi	200795|Chloroflexi	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GZD3_k127_1908299_2	316274.Haur_3817	8.956e-68	244.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_1908299_4	861208.AGROH133_07383	5.198e-56	207.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,4B737@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_1908299_7	36809.MAB_1705c	4.554e-37	151.0	COG1802@1|root,COG1802@2|Bacteria,2I8SM@201174|Actinobacteria,235P2@1762|Mycobacteriaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD3_k127_1908299_0	485913.Krac_10867	5.656e-184	598.0	COG0488@1|root,COG0488@2|Bacteria,2G82M@200795|Chloroflexi	2|Bacteria	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	tlrC	-	-	ko:K06158,ko:K18230	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000,ko03012	3.A.1.120	-	-	ABC_tran,ABC_tran_Xtn
GZD3_k127_1908299_9	1382306.JNIM01000001_gene2639	3.11e-21	106.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GZD3_k127_1908299_10	861299.J421_5893	3.741e-09	69.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_1908299_5	234267.Acid_1288	5.623e-55	205.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GZD3_k127_19090_2	309801.trd_A0017	4.617e-135	441.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
GZD3_k127_19090_1	469383.Cwoe_2797	2.882e-182	574.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CTGY@84995|Rubrobacteria	84995|Rubrobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD3_k127_19090_0	1157638.KB892165_gene3711	3.914e-191	603.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
GZD3_k127_19090_3	675635.Psed_0672	1.205e-60	211.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4EBN0@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_19090_4	1323663.AROI01000046_gene3914	5.805e-16	84.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281	GATase_6,SIS
GZD3_k127_1910141_2	485913.Krac_8380	9.718e-59	211.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD3_k127_1910141_9	1382306.JNIM01000001_gene107	7.272e-05	55.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,zinc_ribbon_2
GZD3_k127_1910141_6	485913.Krac_11993	5.864e-31	129.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GZD3_k127_1910141_4	1382356.JQMP01000003_gene1359	2.092e-42	179.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GZD3_k127_1910141_0	1382306.JNIM01000001_gene2393	4.113e-60	226.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
GZD3_k127_1910141_1	485913.Krac_7240	6.5e-59	218.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1910141_7	525904.Tter_2547	9.264e-23	111.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1910141_10	1382356.JQMP01000003_gene1440	0.0008097	47.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_1910141_8	324602.Caur_2690	5.238e-06	51.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
GZD3_k127_1910141_5	1236902.ANAS01000024_gene3124	7.08e-36	144.0	COG0439@1|root,COG1042@1|root,COG1670@1|root,COG0439@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4EH0E@85012|Streptosporangiales	201174|Actinobacteria	CJ	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
GZD3_k127_1910141_3	485913.Krac_3556	3.815e-52	198.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GZD3_k127_1925728_0	525904.Tter_1861	2.225e-157	501.0	COG2141@1|root,COG2141@2|Bacteria,2NQJG@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_1925728_1	266117.Rxyl_0961	1.298e-87	299.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
GZD3_k127_1925728_2	479434.Sthe_2612	4.949e-31	127.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,27YIQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
GZD3_k127_192778_3	1385519.N801_01895	6.394e-121	401.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GZD3_k127_192778_0	1051632.TPY_0253	6.045e-249	781.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia	186801|Clostridia	C	L-lactate permease	glcA	-	-	ko:K02550,ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14,2.A.14.1.2	-	-	Lactate_perm
GZD3_k127_192778_1	986075.CathTA2_2080	1.463e-223	704.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli	91061|Bacilli	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
GZD3_k127_192778_5	309801.trd_0497	3.225e-112	370.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi,27YSC@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
GZD3_k127_192778_4	1032480.MLP_40790	2.072e-113	381.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4DPV1@85009|Propionibacteriales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GZD3_k127_192778_12	479434.Sthe_1099	3.609e-48	188.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
GZD3_k127_192778_6	485913.Krac_4189	3.279e-107	354.0	COG2074@1|root,COG2074@2|Bacteria	2|Bacteria	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,Cytidylate_kin
GZD3_k127_192778_10	395961.Cyan7425_1594	1.735e-68	237.0	COG4977@1|root,COG4977@2|Bacteria,1GR33@1117|Cyanobacteria	1117|Cyanobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
GZD3_k127_192778_16	479434.Sthe_0372	2.072e-16	83.0	COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi,27YMM@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
GZD3_k127_192778_7	485913.Krac_8244	9.856e-106	355.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi	200795|Chloroflexi	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
GZD3_k127_192778_15	1382306.JNIM01000001_gene3741	1.483e-24	108.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GZD3_k127_192778_13	485913.Krac_8246	4.088e-47	177.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
GZD3_k127_192778_14	1382306.JNIM01000001_gene3743	1.635e-25	111.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
GZD3_k127_192778_2	485913.Krac_2134	1.902e-126	412.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GZD3_k127_192778_8	1382306.JNIM01000001_gene1596	8.12e-91	306.0	COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_192778_11	1382306.JNIM01000001_gene3780	9.94e-67	237.0	COG1235@1|root,COG1235@2|Bacteria,2G711@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GZD3_k127_1942147_2	485913.Krac_1373	4.137e-54	197.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GZD3_k127_1942147_1	1382306.JNIM01000001_gene1815	2.764e-55	200.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
GZD3_k127_1942147_0	485913.Krac_9804	7.327e-88	299.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GZD3_k127_1958398_9	1123073.KB899243_gene844	4.244e-11	70.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
GZD3_k127_1958398_7	1382306.JNIM01000001_gene3733	7.434e-39	154.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
GZD3_k127_1958398_10	543632.JOJL01000027_gene2804	8.276e-08	63.0	2AYAN@1|root,31QD6@2|Bacteria,2H0HE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_1958398_4	485913.Krac_10552	2.549e-65	245.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1958398_6	485913.Krac_10552	4.797e-57	216.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_1958398_2	765698.Mesci_0879	1.179e-77	269.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,43J44@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GZD3_k127_1958398_3	266835.14024522	5.291e-76	260.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria,43ITC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
GZD3_k127_1958398_5	557599.MKAN_03700	1.613e-61	223.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,2369X@1762|Mycobacteriaceae	201174|Actinobacteria	S	short-chain dehydrogenase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
GZD3_k127_1958398_1	485913.Krac_0253	1.717e-80	286.0	28IEQ@1|root,2Z8GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
GZD3_k127_1958398_0	485913.Krac_5196	2.471e-110	367.0	COG2334@1|root,COG2334@2|Bacteria,2G71B@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aminoglycoside phosphotransferase	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
GZD3_k127_1958398_8	1379270.AUXF01000001_gene2805	3.144e-36	150.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
GZD3_k127_195909_2	1382306.JNIM01000001_gene1675	3.442e-62	216.0	COG4608@1|root,COG4608@2|Bacteria,2G80T@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
GZD3_k127_195909_0	749414.SBI_07370	1.294e-89	306.0	COG2159@1|root,COG2159@2|Bacteria,2GP75@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	4.1.1.52	ko:K22213	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_2
GZD3_k127_195909_1	1267535.KB906767_gene1609	2.849e-80	276.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GZD3_k127_1960985_2	1449976.KALB_7476	3.648e-35	144.0	COG3899@1|root,COG3899@2|Bacteria,2H42P@201174|Actinobacteria	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
GZD3_k127_1960985_4	1146883.BLASA_2675	1.052e-16	87.0	2EFG7@1|root,3398W@2|Bacteria,2ID0P@201174|Actinobacteria	201174|Actinobacteria	L	Recombination endonuclease VII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_7
GZD3_k127_1960985_3	293826.Amet_3171	7.941e-20	102.0	COG3081@1|root,COG3081@2|Bacteria,1V278@1239|Firmicutes,249YK@186801|Clostridia,36DIZ@31979|Clostridiaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
GZD3_k127_1960985_0	1382306.JNIM01000001_gene2862	1.619e-228	742.0	COG1112@1|root,COG1112@2|Bacteria,2G6PW@200795|Chloroflexi	200795|Chloroflexi	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,Dna2
GZD3_k127_1960985_1	926550.CLDAP_06990	3.795e-110	372.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
GZD3_k127_1975043_1	485913.Krac_4111	2.149e-67	242.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_1975043_2	266117.Rxyl_2708	1.912e-63	225.0	COG1695@1|root,COG1695@2|Bacteria,2IG8U@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_1975043_0	357808.RoseRS_1297	9.643e-148	502.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
GZD3_k127_2008598_5	357808.RoseRS_1474	3.727e-45	173.0	COG0758@1|root,COG0758@2|Bacteria	2|Bacteria	LU	DNA mediated transformation	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GZD3_k127_2008598_8	1382306.JNIM01000001_gene3368	3.226e-10	74.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_2008598_7	1382306.JNIM01000001_gene2030	1.267e-24	121.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2008598_1	1382306.JNIM01000001_gene2551	8.149e-99	334.0	KOG2524@1|root,2ZJ84@2|Bacteria,2G826@200795|Chloroflexi	200795|Chloroflexi	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
GZD3_k127_2008598_6	326427.Cagg_1614	7.277e-38	152.0	COG1592@1|root,COG3448@1|root,COG1592@2|Bacteria,COG3448@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	rbr3A	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP,Rubrerythrin
GZD3_k127_2008598_9	1121946.AUAX01000005_gene5543	4.98e-06	59.0	COG1716@1|root,COG1716@2|Bacteria,2GPIF@201174|Actinobacteria,4DFS8@85008|Micromonosporales	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2008598_2	485913.Krac_2381	6.664e-95	325.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD3_k127_2008598_4	306281.AJLK01000103_gene3365	1.338e-49	181.0	COG0454@1|root,COG0454@2|Bacteria,1G5EA@1117|Cyanobacteria,1JMBB@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
GZD3_k127_2008598_0	485913.Krac_5082	1.595e-206	652.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
GZD3_k127_2008598_3	485913.Krac_5083	1.123e-87	292.0	COG0640@1|root,COG0640@2|Bacteria,2G9MU@200795|Chloroflexi	200795|Chloroflexi	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GZD3_k127_2011372_0	1230476.C207_00014	1.688e-71	256.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria,3JWD8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GZD3_k127_2011372_1	1521187.JPIM01000172_gene3327	6.384e-18	89.0	COG3415@1|root,COG3415@2|Bacteria,2G9BT@200795|Chloroflexi,3778B@32061|Chloroflexia	32061|Chloroflexia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_202550_10	485913.Krac_0300	4.529e-10	62.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_202550_1	1150864.MILUP08_46439	1.417e-59	218.0	COG4627@1|root,COG4627@2|Bacteria,2IHF2@201174|Actinobacteria,4DGAI@85008|Micromonosporales	201174|Actinobacteria	S	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	BON,Methyltransf_11
GZD3_k127_202550_8	1121381.JNIV01000137_gene1630	1.515e-11	68.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	relB	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
GZD3_k127_202550_6	1173024.KI912148_gene3123	1.813e-25	112.0	COG2026@1|root,COG2026@2|Bacteria,1G99H@1117|Cyanobacteria	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
GZD3_k127_202550_11	666685.R2APBS1_0902	4.552e-08	64.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1X4HS@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
GZD3_k127_202550_12	711393.AYRX01000079_gene5440	0.0007563	44.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,2GMB5@201174|Actinobacteria	201174|Actinobacteria	T	PFAM Metallophosphoesterase	prpA	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
GZD3_k127_202550_9	1449058.JQKT01000007_gene1348	1.21e-10	64.0	2DGXE@1|root,2ZXNB@2|Bacteria,2HTEQ@201174|Actinobacteria,4FT7H@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_202550_4	1382306.JNIM01000001_gene486	2.257e-37	148.0	COG1309@1|root,COG1309@2|Bacteria,2G9FZ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_202550_5	326424.FRAAL2583	8.005e-33	135.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD3_k127_202550_3	526227.Mesil_2725	1.142e-39	156.0	COG3548@1|root,COG3548@2|Bacteria,1WN5V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD3_k127_202550_2	485913.Krac_5347	3.906e-47	170.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
GZD3_k127_202550_0	1380390.JIAT01000010_gene3934	8.998e-124	412.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria,4CRW7@84995|Rubrobacteria	84995|Rubrobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
GZD3_k127_2031509_0	234267.Acid_7324	1.537e-214	684.0	COG0028@1|root,COG0028@2|Bacteria,3Y3QI@57723|Acidobacteria	57723|Acidobacteria	EH	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
GZD3_k127_2050575_0	429009.Adeg_1413	3.844e-32	132.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,42GTM@68295|Thermoanaerobacterales	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
GZD3_k127_2050575_2	485913.Krac_1371	8.945e-17	88.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
GZD3_k127_2050575_1	1382304.JNIL01000001_gene642	9.202e-30	124.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,27A1C@186823|Alicyclobacillaceae	91061|Bacilli	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
GZD3_k127_2053255_11	485913.Krac_7513	3.2e-51	184.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD3_k127_2053255_19	1463825.JNXC01000014_gene7662	1.376e-11	66.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DYEP@85010|Pseudonocardiales	201174|Actinobacteria	V	RND superfamily drug exporter	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GZD3_k127_2053255_14	485913.Krac_11841	4.091e-32	137.0	COG0671@1|root,COG0671@2|Bacteria,2G8YH@200795|Chloroflexi	200795|Chloroflexi	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GZD3_k127_2053255_5	485913.Krac_10853	8.132e-89	314.0	COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi	2|Bacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_2053255_1	525904.Tter_2612	4.722e-152	508.0	COG0477@1|root,COG2814@2|Bacteria,2NQSV@2323|unclassified Bacteria	2|Bacteria	P	Fungal trichothecene efflux pump (TRI12)	mdr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_2053255_6	1382306.JNIM01000001_gene3527	5.231e-86	291.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
GZD3_k127_2053255_16	1304284.L21TH_0916	1.346e-28	115.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,36KM7@31979|Clostridiaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
GZD3_k127_2053255_18	1382306.JNIM01000001_gene3525	1.839e-12	70.0	COG0257@1|root,COG0257@2|Bacteria,2G7GJ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
GZD3_k127_2053255_10	485913.Krac_12504	2.479e-51	187.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
GZD3_k127_2053255_8	1382306.JNIM01000001_gene3523	9.162e-64	220.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
GZD3_k127_2053255_4	1382306.JNIM01000001_gene3522	4.562e-97	326.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GZD3_k127_2053255_2	485913.Krac_12501	4.016e-136	441.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
GZD3_k127_2053255_9	485913.Krac_12500	5.07e-56	204.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
GZD3_k127_2053255_7	1382306.JNIM01000001_gene3519	1.082e-64	232.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
GZD3_k127_2053255_12	1121440.AUMA01000008_gene813	4.636e-48	179.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
GZD3_k127_2053255_13	663278.Ethha_2600	9.338e-47	171.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
GZD3_k127_2053255_21	251229.Chro_1220	1.804e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,1GE9K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
GZD3_k127_2053255_20	314232.SKA53_05925	5.582e-10	72.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2P7TU@245186|Loktanella	28211|Alphaproteobacteria	S	Forms a complex with YaeT, YfiO, and NlpB	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
GZD3_k127_2053255_17	547163.BN979_03039	6.846e-13	74.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,23B9T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GZD3_k127_2053255_3	485913.Krac_7933	5.006e-113	379.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_2053255_0	1382306.JNIM01000001_gene3569	1.333e-162	549.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_23,Rad50_zn_hook,SMC_N
GZD3_k127_2059284_1	1120971.AUCA01000105_gene1157	9.506e-165	527.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli	91061|Bacilli	L	For insertion sequence element IS256 in transposon Tn4001	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_2059284_4	485913.Krac_5813	2.931e-46	177.0	COG0671@1|root,COG0671@2|Bacteria,2G93T@200795|Chloroflexi	200795|Chloroflexi	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GZD3_k127_2059284_0	469383.Cwoe_2409	1.113e-170	577.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
GZD3_k127_2059284_2	469383.Cwoe_2408	1.992e-144	473.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GZD3_k127_2059284_12	1032480.MLP_44550	5.777e-09	59.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4DRIR@85009|Propionibacteriales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_2059284_16	1449347.JQLN01000007_gene1598	3.947e-05	48.0	COG3450@1|root,COG3450@2|Bacteria,2IHPC@201174|Actinobacteria,2M3BE@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
GZD3_k127_2059284_15	1115632.JAFW01000001_gene1835	3.244e-07	56.0	COG3450@1|root,COG3450@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
GZD3_k127_2059284_5	1206732.BAGD01000084_gene3639	5.64e-27	121.0	COG0500@1|root,COG2226@2|Bacteria,2ICJD@201174|Actinobacteria,4FVCF@85025|Nocardiaceae	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_2059284_14	1297865.APJD01000014_gene490	3.922e-08	61.0	COG2329@1|root,COG2329@2|Bacteria,1Q4HA@1224|Proteobacteria,2UN5H@28211|Alphaproteobacteria,3K6BI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD3_k127_2059284_9	1380391.JIAS01000014_gene2202	1.601e-14	78.0	COG0251@1|root,COG0251@2|Bacteria,1RD2M@1224|Proteobacteria,2U7PE@28211|Alphaproteobacteria,2JTUT@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD3_k127_2059284_10	1380391.JIAS01000014_gene2202	2.643e-14	75.0	COG0251@1|root,COG0251@2|Bacteria,1RD2M@1224|Proteobacteria,2U7PE@28211|Alphaproteobacteria,2JTUT@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD3_k127_2059284_17	485913.Krac_5813	0.0004293	44.0	COG0671@1|root,COG0671@2|Bacteria,2G93T@200795|Chloroflexi	200795|Chloroflexi	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
GZD3_k127_2059284_3	479434.Sthe_0598	5.558e-78	293.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GZD3_k127_2059284_11	1120950.KB892714_gene2464	1.002e-11	79.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
GZD3_k127_2059284_6	42256.RradSPS_2816	1.217e-23	103.0	2FCGD@1|root,344JU@2|Bacteria,2IRV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2059284_13	562970.Btus_1995	1.489e-08	63.0	2BYYV@1|root,32X21@2|Bacteria,1VBGY@1239|Firmicutes,4HNH5@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2059284_8	1155714.KB891994_gene4638	2.61e-16	87.0	COG1309@1|root,COG1309@2|Bacteria,2IA4D@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GZD3_k127_206821_0	1122951.ATUE01000006_gene1176	1.989e-139	455.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,3NIR4@468|Moraxellaceae	1236|Gammaproteobacteria	I	Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
GZD3_k127_206821_1	483219.LILAB_11070	1.513e-66	230.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2YW96@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GZD3_k127_2078842_1	485913.Krac_4886	1.57e-34	136.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	tetV	-	-	ko:K18215	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.3	-	-	MFS_1,MFS_3
GZD3_k127_2078842_2	1227352.C173_31576	3.316e-09	69.0	COG0640@1|root,COG0640@2|Bacteria,1VCN0@1239|Firmicutes,4HPCH@91061|Bacilli,26QUC@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GZD3_k127_2078842_0	1382306.JNIM01000001_gene912	4.653e-47	171.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GZD3_k127_2079467_0	1121946.AUAX01000025_gene6337	3.642e-50	186.0	COG1011@1|root,COG1011@2|Bacteria,2HP89@201174|Actinobacteria,4DGIQ@85008|Micromonosporales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
GZD3_k127_20799_0	1298858.AUEL01000003_gene5801	6.656e-88	303.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD3_k127_2099587_6	1449126.JQKL01000026_gene2427	2.451e-05	55.0	COG2823@1|root,COG2823@2|Bacteria,1VC8A@1239|Firmicutes,24NAT@186801|Clostridia	186801|Clostridia	S	periplasmic or secreted lipoprotein	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GZD3_k127_2099587_5	1227487.C474_09984	5.288e-13	83.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota,240VC@183963|Halobacteria	183963|Halobacteria	T	repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
GZD3_k127_2099587_1	1382306.JNIM01000001_gene619	1.866e-126	424.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2
GZD3_k127_2099587_2	1382306.JNIM01000001_gene1295	1.618e-84	299.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GZD3_k127_2099587_0	1111479.AXAR01000009_gene2438	3.85e-141	464.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,279MN@186823|Alicyclobacillaceae	91061|Bacilli	G	FGGY family of carbohydrate kinases, N-terminal domain	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
GZD3_k127_2099587_3	1382306.JNIM01000001_gene2611	7.917e-38	149.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GZD3_k127_2124676_1	485913.Krac_8889	2.382e-41	158.0	2DR9N@1|root,33ATC@2|Bacteria,2G9JG@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
GZD3_k127_2124676_0	1382306.JNIM01000001_gene665	1.389e-97	324.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GZD3_k127_2125783_0	485913.Krac_1820	2.112e-79	283.0	COG4585@1|root,COG4585@2|Bacteria,2G6WZ@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
GZD3_k127_2156647_4	1382306.JNIM01000001_gene3286	3.322e-05	54.0	2DX9N@1|root,34415@2|Bacteria,2G9KZ@200795|Chloroflexi	200795|Chloroflexi	S	sptr c4rri0	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2156647_1	926550.CLDAP_02490	9.084e-46	181.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142,Glyco_hydro_18
GZD3_k127_2156647_3	1278073.MYSTI_06319	6.914e-30	127.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
GZD3_k127_2156647_2	265729.GS18_0201935	1.468e-41	160.0	COG1670@1|root,COG1670@2|Bacteria,1UUXI@1239|Firmicutes,4I685@91061|Bacilli,1ZHU0@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_2156647_0	357808.RoseRS_0406	7.856e-54	201.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,3751B@32061|Chloroflexia	32061|Chloroflexia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GZD3_k127_217375_0	1382306.JNIM01000001_gene2902	2.056e-150	484.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
GZD3_k127_2235110_2	1382306.JNIM01000001_gene2395	3.328e-37	148.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
GZD3_k127_2235110_1	358396.C445_05253	2.4e-43	171.0	arCOG06802@1|root,arCOG06802@2157|Archaea,2XVYT@28890|Euryarchaeota,23TZE@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2235110_0	395964.KE386496_gene635	1.05e-191	610.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,2TUKC@28211|Alphaproteobacteria,3NCUN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N_2,Helicase_C,ResIII
GZD3_k127_2255580_0	1123060.JONP01000033_gene1914	3.644e-92	314.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2JS2T@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
GZD3_k127_226889_3	33876.JNXY01000004_gene1576	3.317e-101	340.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HU5X@201174|Actinobacteria,4DBT0@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8
GZD3_k127_226889_14	1382306.JNIM01000001_gene1020	5.873e-26	125.0	2DNAS@1|root,32WH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phi_1
GZD3_k127_226889_16	251221.35210773	9.618e-25	121.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CBM60,Laminin_G_3,PT-HINT,PT-VENN,RHS_repeat,SprB,Transglut_core
GZD3_k127_226889_10	1382306.JNIM01000001_gene3727	9.042e-52	207.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	He_PIG,Peptidase_S8,Pro-kuma_activ
GZD3_k127_226889_12	1382306.JNIM01000001_gene1579	2.647e-44	166.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GZD3_k127_226889_7	485913.Krac_10478	6.116e-60	215.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GZD3_k127_226889_6	479434.Sthe_2201	3.228e-67	237.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD3_k127_226889_9	926550.CLDAP_05300	3.471e-52	189.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GZD3_k127_226889_5	1122182.KB903833_gene5573	7.918e-91	315.0	COG0477@1|root,COG2814@2|Bacteria,2IF5M@201174|Actinobacteria,4D8SR@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
GZD3_k127_226889_0	1173028.ANKO01000244_gene3949	1.033e-112	369.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
GZD3_k127_226889_13	331869.BAL199_14197	8.24e-43	167.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2TVKR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K13633	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
GZD3_k127_226889_8	1463856.JOHY01000004_gene6507	1.576e-56	201.0	COG2606@1|root,COG2606@2|Bacteria,2IMZE@201174|Actinobacteria	201174|Actinobacteria	G	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GZD3_k127_226889_2	479434.Sthe_0341	4.409e-108	355.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
GZD3_k127_226889_1	479434.Sthe_0342	3.109e-110	362.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
GZD3_k127_226889_15	479434.Sthe_0343	5.388e-25	108.0	2E4G6@1|root,335WF@2|Bacteria,2G9R2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_226889_11	1240349.ANGC01000002_gene2167	8.798e-51	186.0	COG2050@1|root,COG2050@2|Bacteria,2IMN9@201174|Actinobacteria,4G1AQ@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_226889_4	269799.Gmet_3488	2.033e-95	330.0	2DBVK@1|root,2ZBBH@2|Bacteria,1PWZS@1224|Proteobacteria,432W2@68525|delta/epsilon subdivisions,2WXWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GZD3_k127_2274838_0	1382306.JNIM01000001_gene3861	3.687e-139	470.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GZD3_k127_2278149_0	1382306.JNIM01000001_gene936	4.879e-111	370.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Hemerythrin,Rieske
GZD3_k127_2278149_1	485913.Krac_9117	2.669e-20	97.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi	200795|Chloroflexi	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
GZD3_k127_2279065_0	1382306.JNIM01000001_gene4155	3.195e-133	432.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
GZD3_k127_2279065_4	99598.Cal7507_2574	1.931e-12	74.0	COG0864@1|root,COG0864@2|Bacteria,1G868@1117|Cyanobacteria,1HP63@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
GZD3_k127_2279065_3	86106.I862_04795	1.164e-13	79.0	COG0776@1|root,COG0776@2|Bacteria,1QRJM@1224|Proteobacteria,2VAC5@28211|Alphaproteobacteria,47GK7@766|Rickettsiales	766|Rickettsiales	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
GZD3_k127_2279065_2	1382306.JNIM01000001_gene1071	1.059e-34	143.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yngC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD3_k127_2279065_1	1128421.JAGA01000004_gene2555	4.394e-55	199.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15,2.7.7.42,2.7.7.89	ko:K00982,ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GZD3_k127_2281921_2	316274.Haur_4331	3.507e-50	187.0	COG0163@1|root,COG0163@2|Bacteria,2G97A@200795|Chloroflexi	200795|Chloroflexi	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
GZD3_k127_2281921_0	1121945.ATXS01000007_gene506	1.425e-100	358.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
GZD3_k127_2281921_3	485913.Krac_7748	1.008e-38	155.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
GZD3_k127_2281921_1	1382306.JNIM01000001_gene1173	1.477e-75	268.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
GZD3_k127_2281921_4	391596.PBAL39_15634	3.807e-21	99.0	2DFP3@1|root,2ZSIS@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0167)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0167
GZD3_k127_2291381_4	485913.Krac_7761	5.452e-39	153.0	COG0673@1|root,COG0673@2|Bacteria,2G6PI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD3_k127_2291381_2	1382306.JNIM01000001_gene1490	1.651e-75	263.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GZD3_k127_2291381_0	485913.Krac_8070	6.757e-113	374.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
GZD3_k127_2291381_3	1382306.JNIM01000001_gene782	6.331e-72	261.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
GZD3_k127_2291381_1	485913.Krac_2999	9.909e-111	364.0	COG0647@1|root,COG0647@2|Bacteria,2G60W@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
GZD3_k127_2291381_5	1382306.JNIM01000001_gene3285	3.548e-24	104.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	3.2.1.4	ko:K01179,ko:K03832	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	2.C.1.1	GH5,GH9	-	Autotransporter,CarbopepD_reg_2,TonB_C
GZD3_k127_2304060_1	765420.OSCT_3110	1.741e-31	129.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,376DV@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_2304060_0	525904.Tter_1201	4.007e-224	709.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_2304060_2	1122132.AQYH01000007_gene1825	6.053e-15	81.0	COG0494@1|root,COG0494@2|Bacteria,1RM2Y@1224|Proteobacteria,2UAF2@28211|Alphaproteobacteria,4BFSH@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_2304060_3	1116232.AHBF01000038_gene5413	1.271e-05	48.0	2B5TJ@1|root,31YPA@2|Bacteria,2H11K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2304893_3	1232436.CAPF01000076_gene1122	2.319e-10	65.0	COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CYJ8@84998|Coriobacteriia	84998|Coriobacteriia	G	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GZD3_k127_2304893_0	644966.Tmar_2265	5.618e-27	124.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WCXT@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GZD3_k127_2304893_2	68170.KL590489_gene10379	1.148e-19	95.0	2EHCD@1|root,33B48@2|Bacteria,2HSDR@201174|Actinobacteria,4EDD2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2304893_1	68170.KL590489_gene10378	3.237e-20	104.0	294YV@1|root,2ZSBR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2304893_4	298653.Franean1_6999	6.471e-09	68.0	COG2888@1|root,COG2888@2|Bacteria	2|Bacteria	J	peptidyl-tyrosine sulfation	ybeL	-	1.17.4.1,4.6.1.1	ko:K00525,ko:K01768	ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213	M00053,M00695	R00089,R00434,R02017,R02018,R02019,R02024	RC00295,RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DUF1451
GZD3_k127_2307279_2	485913.Krac_9928	7.171e-107	366.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_9928|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2307279_13	1304885.AUEY01000013_gene3126	2.391e-07	63.0	COG0589@1|root,COG0589@2|Bacteria,1QR0W@1224|Proteobacteria,42SGI@68525|delta/epsilon subdivisions,2WPQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_2307279_11	521098.Aaci_0229	8.032e-19	94.0	2DE3B@1|root,2ZKBS@2|Bacteria,1W4YC@1239|Firmicutes,4HZN8@91061|Bacilli	91061|Bacilli	-	-	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	-
GZD3_k127_2307279_1	1382306.JNIM01000001_gene3934	2.832e-121	405.0	COG3278@1|root,COG3278@2|Bacteria,2G7C6@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2307279_9	1382306.JNIM01000001_gene3933	6.723e-26	109.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
GZD3_k127_2307279_4	1382306.JNIM01000001_gene3932	2.602e-71	261.0	COG0664@1|root,COG0664@2|Bacteria,2G6XU@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD3_k127_2307279_10	1172188.KB911829_gene4441	1.199e-19	98.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4FGHD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2307279_0	1382306.JNIM01000001_gene2212	2.429e-123	406.0	COG1275@1|root,COG1275@2|Bacteria	2|Bacteria	P	C4-dicarboxylate transporter malic acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
GZD3_k127_2307279_6	867903.ThesuDRAFT_01329	2.491e-40	160.0	COG4309@1|root,COG4309@2|Bacteria,1VHYE@1239|Firmicutes,24RCX@186801|Clostridia	186801|Clostridia	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
GZD3_k127_2307279_5	485913.Krac_12620	4.459e-50	195.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,RmlD_sub_bind
GZD3_k127_2307279_3	479434.Sthe_2453	2.075e-99	332.0	COG2761@1|root,COG2761@2|Bacteria,2G96N@200795|Chloroflexi	200795|Chloroflexi	Q	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2307279_12	1382306.JNIM01000001_gene3936	1.584e-08	60.0	COG4309@1|root,COG4309@2|Bacteria,2G936@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
GZD3_k127_2307279_7	1382306.JNIM01000001_gene3935	1.141e-35	138.0	COG2151@1|root,COG2151@2|Bacteria,2G75C@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GZD3_k127_2307792_0	1382306.JNIM01000001_gene3731	1.658e-131	462.0	COG0577@1|root,COG0577@2|Bacteria,2G6CK@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_2307792_2	1382306.JNIM01000001_gene3732	2.874e-40	159.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD3_k127_2307792_1	35754.JNYJ01000019_gene80	1.316e-103	370.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12
GZD3_k127_2307792_3	479434.Sthe_1901	7.118e-05	52.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi,27Y4K@189775|Thermomicrobia	189775|Thermomicrobia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
GZD3_k127_2308965_1	1187851.A33M_0226	2.512e-06	61.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
GZD3_k127_2308965_0	485913.Krac_9000	3.361e-16	81.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
GZD3_k127_2315026_8	107635.AZUO01000001_gene949	1.783e-13	79.0	COG0451@1|root,COG0451@2|Bacteria,1MVPZ@1224|Proteobacteria,2U553@28211|Alphaproteobacteria,36Z83@31993|Methylocystaceae	28211|Alphaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.135,1.1.1.281	ko:K15856,ko:K22252	ko00051,ko00520,map00051,map00520	-	R03396,R03397,R03398,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GZD3_k127_2315026_3	867845.KI911784_gene1522	1.296e-142	459.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GZD3_k127_2315026_4	1382306.JNIM01000001_gene1493	6.547e-128	431.0	COG3307@1|root,COG3307@2|Bacteria,2G8JW@200795|Chloroflexi	200795|Chloroflexi	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD3_k127_2315026_6	1382306.JNIM01000001_gene1495	8.804e-63	226.0	COG0489@1|root,COG0489@2|Bacteria,2G9JT@200795|Chloroflexi	200795|Chloroflexi	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2315026_1	1382306.JNIM01000001_gene1502	4.782e-146	473.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	K_oxygenase,Pyr_redox_2,Pyr_redox_3
GZD3_k127_2315026_0	485913.Krac_8066	6.271e-157	507.0	COG3919@1|root,COG3919@2|Bacteria,2G80M@200795|Chloroflexi	200795|Chloroflexi	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2315026_2	1382306.JNIM01000001_gene2996	1.278e-143	489.0	COG2244@1|root,COG2244@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
GZD3_k127_2315026_7	485913.Krac_8068	5.711e-62	242.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
GZD3_k127_2315026_9	1234364.AMSF01000037_gene203	6.614e-09	59.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,1RV5Q@1236|Gammaproteobacteria,1XB6H@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GZD3_k127_2316698_5	1382306.JNIM01000001_gene840	4.823e-25	114.0	COG1555@1|root,COG1555@2|Bacteria,2G771@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
GZD3_k127_2316698_6	1121403.AUCV01000051_gene2123	3.369e-19	100.0	COG0746@1|root,COG1526@1|root,COG0746@2|Bacteria,COG1526@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2WP3Q@28221|Deltaproteobacteria,2MK7Z@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
GZD3_k127_2316698_1	1386089.N865_11335	1.25e-145	479.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2316698_3	1267535.KB906767_gene5398	8.589e-71	260.0	COG2837@1|root,COG2837@2|Bacteria	2|Bacteria	P	iron assimilation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2316698_2	1382306.JNIM01000001_gene2642	3.323e-94	318.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	efeU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1,Peptidase_M75
GZD3_k127_2316698_0	309801.trd_1825	8.531e-161	520.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,27XTS@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GZD3_k127_2316698_4	404589.Anae109_2816	1.397e-65	236.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_2317217_0	765420.OSCT_2440	0.0	1265.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,37520@32061|Chloroflexia	32061|Chloroflexia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
GZD3_k127_2317217_3	861299.J421_6000	1.044e-36	142.0	COG0789@1|root,COG0789@2|Bacteria,1ZVAN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR, DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	-
GZD3_k127_2317217_4	886377.Murru_2464	1.336e-07	58.0	arCOG13956@1|root,33BWW@2|Bacteria,4P4JQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2317217_5	590998.Celf_2293	1.45e-06	62.0	COG2905@1|root,COG2905@2|Bacteria,2HY5B@201174|Actinobacteria,4F319@85016|Cellulomonadaceae	201174|Actinobacteria	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
GZD3_k127_2317217_1	485913.Krac_2911	1.934e-139	473.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G7G9@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
GZD3_k127_2317217_2	479434.Sthe_0697	1.037e-51	196.0	COG5495@1|root,COG5495@2|Bacteria,2G6F3@200795|Chloroflexi,27YA4@189775|Thermomicrobia	189775|Thermomicrobia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
GZD3_k127_2320679_0	234267.Acid_3935	9.135e-124	407.0	COG1181@1|root,COG1181@2|Bacteria,3Y9AM@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
GZD3_k127_2320679_1	485913.Krac_8346	4.199e-77	280.0	COG0515@1|root,COG0515@2|Bacteria	485913.Krac_8346|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2320679_2	383372.Rcas_4353	1.962e-37	156.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GZD3_k127_2322836_6	1089545.KB913037_gene3625	2.945e-07	63.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria,4E7JT@85010|Pseudonocardiales	201174|Actinobacteria	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,RicinB_lectin_2
GZD3_k127_2322836_2	485913.Krac_11687	5.592e-85	299.0	COG0664@1|root,COG0664@2|Bacteria,2G6YS@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
GZD3_k127_2322836_1	1382306.JNIM01000001_gene725	6.58e-92	310.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
GZD3_k127_2322836_3	1382306.JNIM01000001_gene448	2.408e-65	252.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PP2C
GZD3_k127_2322836_0	316274.Haur_3189	1.729e-93	319.0	COG2301@1|root,COG2301@2|Bacteria,2G6EA@200795|Chloroflexi,375UN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the HpcH HpaI aldolase family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
GZD3_k127_2322836_5	485913.Krac_11686	8.165e-17	85.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GZD3_k127_2326114_2	485913.Krac_9133	2.941e-10	66.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GZD3_k127_2326114_0	485913.Krac_9132	7.628e-157	509.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD3_k127_2326114_1	485913.Krac_10314	5.107e-93	314.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
GZD3_k127_2327879_2	485913.Krac_8174	4.197e-66	226.0	COG2718@1|root,COG2718@2|Bacteria,2G6DB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
GZD3_k127_2327879_0	485913.Krac_8173	0.0	1152.0	COG1372@1|root,COG2719@1|root,COG1372@2|Bacteria,COG2719@2|Bacteria,2G83B@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SpoVR family protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	Intein_splicing,LAGLIDADG_3,SpoVR
GZD3_k127_2327879_1	1157632.AQWQ01000005_gene879	2.825e-66	231.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
GZD3_k127_2327879_3	300852.55771564	1.046e-17	89.0	COG4113@1|root,COG4113@2|Bacteria,1WJXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_2327879_4	485913.Krac_10794	9.311e-10	59.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GZD3_k127_2331398_2	479434.Sthe_0072	1.14e-92	333.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
GZD3_k127_2331398_7	1382306.JNIM01000001_gene1269	1.684e-37	146.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene1269|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2331398_5	1382306.JNIM01000001_gene2931	7.245e-46	184.0	COG0642@1|root,COG2205@2|Bacteria,2G8UJ@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GZD3_k127_2331398_3	1382306.JNIM01000001_gene3659	1.689e-86	308.0	COG0833@1|root,COG0833@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
GZD3_k127_2331398_8	345341.KUTG_00298	0.0002167	55.0	COG1476@1|root,COG3903@1|root,COG1476@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DXCW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_10,TPR_12,TPR_7,Trans_reg_C
GZD3_k127_2331398_6	485913.Krac_9041	5.559e-40	152.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
GZD3_k127_2331398_1	485913.Krac_9042	7.826e-95	318.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
GZD3_k127_2331398_4	1382306.JNIM01000001_gene3470	6.118e-64	228.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
GZD3_k127_2331398_0	326427.Cagg_1046	1.604e-132	431.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi,3751Y@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD1	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
GZD3_k127_2332005_0	485913.Krac_8830	2.563e-117	394.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GZD3_k127_2332005_4	485913.Krac_11120	3.862e-33	135.0	COG0745@1|root,COG0745@2|Bacteria,2G9Q2@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_2332005_2	1382306.JNIM01000001_gene770	8.517e-85	286.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
GZD3_k127_2332005_3	1183438.GKIL_4241	1.066e-62	226.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
GZD3_k127_2332005_5	867845.KI911784_gene3681	2.095e-31	139.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
GZD3_k127_2332005_1	479434.Sthe_2436	1.247e-94	315.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GZD3_k127_2336564_4	485913.Krac_10788	2.976e-27	116.0	COG0720@1|root,COG0720@2|Bacteria,2G919@200795|Chloroflexi	200795|Chloroflexi	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
GZD3_k127_2336564_1	1382306.JNIM01000001_gene3513	7.757e-202	635.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GZD3_k127_2336564_5	436229.JOEH01000016_gene7106	5.633e-08	63.0	COG2211@1|root,COG2211@2|Bacteria,2GR8I@201174|Actinobacteria,2NFUS@228398|Streptacidiphilus	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_2336564_0	926560.KE387023_gene2636	1.129e-293	926.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1WIM7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
GZD3_k127_2336564_2	1382306.JNIM01000001_gene3959	1.513e-70	247.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
GZD3_k127_2338747_1	1382306.JNIM01000001_gene2613	1.318e-46	170.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GZD3_k127_2338747_0	485913.Krac_8137	1.174e-115	389.0	COG0747@1|root,COG0747@2|Bacteria,2G880@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_2339527_4	1382306.JNIM01000001_gene1280	4.304e-62	242.0	COG0457@1|root,COG0457@2|Bacteria	1382306.JNIM01000001_gene1280|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2339527_3	1382306.JNIM01000001_gene4052	1.744e-66	238.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD3_k127_2339527_8	477641.MODMU_3040	1.306e-20	104.0	2B3RV@1|root,31WFF@2|Bacteria,2GX6M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2339527_5	485913.Krac_8242	2.694e-51	188.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
GZD3_k127_2339527_1	485913.Krac_4797	3.344e-94	327.0	2DMGS@1|root,32RE8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2339527_0	1382306.JNIM01000001_gene2555	7.654e-173	556.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
GZD3_k127_2339527_7	1382356.JQMP01000003_gene1608	1.415e-43	164.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_2339527_6	1382356.JQMP01000003_gene1609	1.337e-46	171.0	COG1055@1|root,COG1055@2|Bacteria,2GAQ8@200795|Chloroflexi,27YXR@189775|Thermomicrobia	189775|Thermomicrobia	P	Citrate transporter	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
GZD3_k127_2339527_9	485913.Krac_1779	9.495e-17	88.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD3_k127_2339527_2	338966.Ppro_3581	5.374e-90	300.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
GZD3_k127_2339527_10	65393.PCC7424_4288	5.52e-08	63.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1	ko:K11894,ko:K11913,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	3.A.23.1	-	-	FHA,Yop-YscD_cpl,zf-ribbon_3
GZD3_k127_2346759_2	525904.Tter_0148	0.0001065	50.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD3_k127_2346759_0	1128421.JAGA01000003_gene3702	8.854e-154	507.0	COG0859@1|root,COG0859@2|Bacteria,2NPXQ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD3_k127_2346759_1	479434.Sthe_0042	8.536e-87	295.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2G87I@200795|Chloroflexi,27YW4@189775|Thermomicrobia	189775|Thermomicrobia	H	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
GZD3_k127_2353131_0	1379270.AUXF01000002_gene1838	7.934e-213	677.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
GZD3_k127_2355446_4	1382306.JNIM01000001_gene4037	2.315e-34	137.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
GZD3_k127_2355446_1	864702.OsccyDRAFT_1551	2.349e-157	515.0	COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria,1H763@1150|Oscillatoriales	1117|Cyanobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
GZD3_k127_2355446_5	869210.Marky_1973	8.756e-33	134.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
GZD3_k127_2355446_3	390989.JOEG01000009_gene940	1.023e-39	159.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4DB7S@85008|Micromonosporales	201174|Actinobacteria	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GZD3_k127_2355446_2	485913.Krac_8615	3.714e-42	162.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
GZD3_k127_2355446_0	1382306.JNIM01000001_gene134	2.618e-173	551.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
GZD3_k127_2356145_24	485913.Krac_7478	9.744e-07	61.0	COG1994@1|root,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
GZD3_k127_2356145_17	1399115.U719_06830	1.228e-27	119.0	COG1670@1|root,COG1670@2|Bacteria,1V449@1239|Firmicutes,4HJA0@91061|Bacilli	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
GZD3_k127_2356145_23	1283299.AUKG01000001_gene3036	6.749e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2HG39@201174|Actinobacteria,4CP8K@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2356145_14	1128421.JAGA01000002_gene1306	2.128e-33	134.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_2356145_6	1382306.JNIM01000001_gene4167	3.331e-55	201.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
GZD3_k127_2356145_7	1382306.JNIM01000001_gene4168	2.509e-54	200.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD3_k127_2356145_16	349161.Dred_2481	5.145e-29	123.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia	186801|Clostridia	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
GZD3_k127_2356145_12	485913.Krac_7648	4.004e-34	141.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
GZD3_k127_2356145_21	1469607.KK073768_gene4628	2.184e-16	83.0	2EHRH@1|root,33BH9@2|Bacteria,1GA8J@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
GZD3_k127_2356145_15	459495.SPLC1_S201110	6.548e-30	123.0	2E953@1|root,333DW@2|Bacteria,1G8VT@1117|Cyanobacteria,1HFXG@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2356145_18	1120954.ATXE01000003_gene303	3.098e-24	117.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DP00@85009|Propionibacteriales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
GZD3_k127_2356145_1	485913.Krac_10801	1.851e-199	644.0	COG1506@1|root,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GZD3_k127_2356145_26	305700.B447_10758	1.101e-05	53.0	2DU19@1|root,33NHC@2|Bacteria,1NKNM@1224|Proteobacteria,2VYQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2356145_3	383372.Rcas_3221	2.27e-80	280.0	COG2199@1|root,COG3706@2|Bacteria,2G8GT@200795|Chloroflexi,374RS@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
GZD3_k127_2356145_10	1382306.JNIM01000001_gene1642	1.498e-45	170.0	COG1051@1|root,COG1051@2|Bacteria,2G8SP@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_2356145_20	1120934.KB894429_gene1665	1.777e-21	98.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD3_k127_2356145_2	485913.Krac_8201	4.79e-92	317.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
GZD3_k127_2356145_9	485913.Krac_8202	6.197e-46	182.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
GZD3_k127_2356145_5	485913.Krac_6474	3.181e-61	217.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_2356145_25	670292.JH26_11315	8.092e-06	57.0	COG1674@1|root,COG4783@1|root,COG1674@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	ftsK	-	-	ko:K02660,ko:K03466,ko:K07474,ko:K19175	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044,ko02048,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
GZD3_k127_2356145_22	573061.Clocel_1277	6.154e-16	88.0	COG0443@1|root,COG0443@2|Bacteria,1VQXJ@1239|Firmicutes,24B9M@186801|Clostridia,36GRE@31979|Clostridiaceae	186801|Clostridia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
GZD3_k127_2356145_13	208444.JNYY01000011_gene2952	1.377e-33	138.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4EBAP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2356145_0	1123368.AUIS01000001_gene1948	8.987e-274	863.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,1RYY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_2356145_4	1123368.AUIS01000001_gene1949	2.13e-62	218.0	2C4GJ@1|root,2ZD2G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2356145_8	266117.Rxyl_2819	4.659e-53	195.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
GZD3_k127_2356145_19	1173027.Mic7113_0498	7.28e-24	104.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GZD3_k127_2359340_0	485913.Krac_1267	5.36e-152	488.0	COG4586@1|root,COG4586@2|Bacteria	2|Bacteria	S	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_2359340_2	1540221.JQNI01000002_gene2896	2.738e-80	278.0	2DB86@1|root,2Z7QD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
GZD3_k127_2359340_1	1173027.Mic7113_2540	3.456e-99	332.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
GZD3_k127_2359340_3	485913.Krac_10498	1.365e-32	130.0	COG0745@1|root,COG0745@2|Bacteria,2G9E3@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_2370208_0	1382306.JNIM01000001_gene1042	2.861e-170	552.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
GZD3_k127_2370208_1	215803.DB30_5068	1.601e-08	61.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42QJX@68525|delta/epsilon subdivisions,2WKPN@28221|Deltaproteobacteria,2Z26U@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD3_k127_2380705_0	1382306.JNIM01000001_gene1396	2.893e-147	481.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
GZD3_k127_2380705_1	1200792.AKYF01000025_gene6051	3.398e-131	441.0	COG0714@1|root,COG1112@1|root,COG0714@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli,26VZZ@186822|Paenibacillaceae	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
GZD3_k127_2382140_3	1122939.ATUD01000012_gene3191	8.752e-13	82.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,2IIQJ@201174|Actinobacteria,4CR1G@84995|Rubrobacteria	84995|Rubrobacteria	T	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
GZD3_k127_2382140_2	926550.CLDAP_25550	4.474e-43	180.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_2382140_1	1382306.JNIM01000001_gene1045	3.48e-69	241.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_2382140_0	485913.Krac_9676	2.646e-89	296.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	tcmP	-	-	-	-	-	-	-	-	-	-	-	LCM
GZD3_k127_2390864_2	765420.OSCT_2952	1.213e-29	126.0	COG0514@1|root,COG0514@2|Bacteria,2G6S8@200795|Chloroflexi,376TB@32061|Chloroflexia	32061|Chloroflexia	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
GZD3_k127_2390864_0	1120985.AUMI01000007_gene2528	1.638e-87	299.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4H39N@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
GZD3_k127_2390864_3	485913.Krac_8568	5.839e-16	82.0	COG3654@1|root,COG3654@2|Bacteria,2G7HS@200795|Chloroflexi	200795|Chloroflexi	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
GZD3_k127_2390864_4	748449.Halha_1477	0.0006148	46.0	COG2336@1|root,COG2336@2|Bacteria,1UMZD@1239|Firmicutes,25GT0@186801|Clostridia,3WCBX@53433|Halanaerobiales	186801|Clostridia	T	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GZD3_k127_2396650_2	479434.Sthe_1008	6.298e-37	147.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2396650_0	479434.Sthe_1008	9.579e-70	252.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2396650_3	926554.KI912674_gene2518	1.02e-12	77.0	COG0454@1|root,COG0456@2|Bacteria,1WM6D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2396650_4	926560.KE387023_gene2236	9.998e-05	48.0	COG0454@1|root,COG0456@2|Bacteria	926560.KE387023_gene2236|-	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2396650_1	357808.RoseRS_1238	2.693e-40	162.0	COG0454@1|root,COG0456@2|Bacteria,2G8KY@200795|Chloroflexi,377BQ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2404192_0	765420.OSCT_1210	5.009e-219	693.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,376YS@32061|Chloroflexia	32061|Chloroflexia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
GZD3_k127_2404461_4	479434.Sthe_0935	6.098e-31	124.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,27XJV@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
GZD3_k127_2404461_0	309801.trd_0214	3.081e-127	421.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi,27XK1@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GZD3_k127_2404461_2	316274.Haur_3992	7.498e-98	337.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,376MF@32061|Chloroflexia	32061|Chloroflexia	F	PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
GZD3_k127_2404461_3	255470.cbdbA1112	6.496e-60	214.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,34D9M@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
GZD3_k127_2404461_5	593117.TGAM_0059	1.61e-21	107.0	COG0852@1|root,COG3261@1|root,arCOG01547@2157|Archaea,arCOG01551@2157|Archaea,2Y7K6@28890|Euryarchaeota,243QV@183968|Thermococci	183968|Thermococci	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
GZD3_k127_2404461_8	1176165.CAJD01000019_gene1340	1.121e-06	62.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4F8WQ@85019|Brevibacteriaceae	201174|Actinobacteria	CP	Domain related to MnhB subunit of Na+/H+ antiporter	mnhB	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,NADHdh,Proton_antipo_M,Proton_antipo_N
GZD3_k127_2404461_6	1244869.H261_02206	8.66e-20	97.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2U279@28211|Alphaproteobacteria,2JSJJ@204441|Rhodospirillales	204441|Rhodospirillales	C	oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
GZD3_k127_2404461_1	484770.UFO1_3275	1.403e-108	366.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
GZD3_k127_2404461_7	1122223.KB890701_gene2340	1.731e-13	74.0	COG0639@1|root,COG0639@2|Bacteria,1WJXV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD3_k127_2406176_3	485913.Krac_10615	3.175e-38	157.0	COG1266@1|root,COG1266@2|Bacteria,2G9H5@200795|Chloroflexi	200795|Chloroflexi	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD3_k127_2406176_1	234267.Acid_3243	6.365e-136	453.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,DUF11,NPCBM_assoc
GZD3_k127_2406176_5	485913.Krac_1981	1.112e-14	84.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP,GBS_Bsp-like
GZD3_k127_2406176_9	1051632.TPY_0243	0.0005305	48.0	COG3255@1|root,COG3255@2|Bacteria,1V88A@1239|Firmicutes,24KTK@186801|Clostridia	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD3_k127_2406176_0	1123256.KB907945_gene380	5.917e-156	506.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,1S0H2@1236|Gammaproteobacteria,1X5B7@135614|Xanthomonadales	135614|Xanthomonadales	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD3_k127_2406176_8	272123.Anacy_0954	6.149e-09	61.0	COG2886@1|root,COG2886@2|Bacteria,1GK0K@1117|Cyanobacteria,1HT0P@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
GZD3_k127_2406176_6	768671.ThimaDRAFT_3665	1.109e-12	71.0	COG2405@1|root,COG2405@2|Bacteria,1NI7Q@1224|Proteobacteria,1SIDT@1236|Gammaproteobacteria,1X1UT@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GZD3_k127_2406176_7	56110.Oscil6304_0172	4.185e-11	66.0	COG2405@1|root,COG2405@2|Bacteria,1G5MB@1117|Cyanobacteria	2|Bacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
GZD3_k127_2406176_2	1192034.CAP_6068	1.367e-133	432.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2YY3U@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
GZD3_k127_24073_1	1041930.Mtc_1547	1.202e-61	218.0	COG3408@1|root,arCOG03287@2157|Archaea,2XU8W@28890|Euryarchaeota	28890|Euryarchaeota	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_24073_6	224308.BSU28340	5.638e-06	57.0	COG3861@1|root,COG3861@2|Bacteria,1V9A1@1239|Firmicutes,4HISC@91061|Bacilli,1ZE4F@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ysnF	-	-	-	-	-	-	-	-	-	-	-	DUF2382,YflT
GZD3_k127_24073_2	485913.Krac_9923	1.737e-24	115.0	COG3861@1|root,COG3861@2|Bacteria,2G9D9@200795|Chloroflexi	200795|Chloroflexi	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24073_5	886293.Sinac_4599	5.087e-09	64.0	COG3861@1|root,COG3861@2|Bacteria,2J0X2@203682|Planctomycetes	203682|Planctomycetes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24073_4	1211815.CBYP010000002_gene1981	6.733e-10	71.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4EV5Z@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
GZD3_k127_24073_3	397278.JOJN01000022_gene3718	1.04e-16	91.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4DRXH@85009|Propionibacteriales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
GZD3_k127_24073_0	485913.Krac_6742	8.569e-83	288.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GZD3_k127_2408314_8	485913.Krac_4331	7.812e-21	97.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_2408314_3	1382306.JNIM01000001_gene901	7.271e-77	284.0	COG0630@1|root,COG0630@2|Bacteria,2G943@200795|Chloroflexi	200795|Chloroflexi	NU	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2408314_5	485913.Krac_7851	9.653e-57	215.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD3_k127_2408314_7	1382306.JNIM01000001_gene3871	5.042e-34	143.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
GZD3_k127_2408314_4	1382306.JNIM01000001_gene2623	3.525e-65	238.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
GZD3_k127_2408314_10	1151292.QEW_3909	5.564e-06	56.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25RV3@186804|Peptostreptococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
GZD3_k127_2408314_9	1079986.JH164846_gene1937	3.806e-15	80.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2408314_1	1121378.KB899713_gene717	5.852e-109	357.0	COG3340@1|root,COG3340@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
GZD3_k127_2408314_0	479435.Kfla_2275	4.716e-115	381.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DR0C@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2408314_2	485913.Krac_1023	2.024e-102	347.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	nucA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
GZD3_k127_2408315_8	255470.cbdbA547	5.705e-21	98.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_2408315_5	1382306.JNIM01000001_gene1274	6.824e-85	296.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	-	-	ko:K02033,ko:K13894	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
GZD3_k127_2408315_6	1382306.JNIM01000001_gene1273	1.05e-82	289.0	COG1173@1|root,COG1173@2|Bacteria,2G8N2@200795|Chloroflexi	200795|Chloroflexi	EP	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
GZD3_k127_2408315_2	1128421.JAGA01000002_gene833	1.041e-124	407.0	COG0444@1|root,COG0444@2|Bacteria,2NQAA@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD3_k127_2408315_1	1382306.JNIM01000001_gene1271	6.783e-147	475.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD3_k127_2408315_4	1382306.JNIM01000001_gene172	1.175e-86	311.0	COG0840@1|root,COG2203@1|root,COG0840@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	mcp40H-1	-	-	ko:K02660,ko:K03406,ko:K11525	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	GAF,HAMP,MCPsignal,dCache_1
GZD3_k127_2408315_7	1382306.JNIM01000001_gene3094	1.323e-72	254.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
GZD3_k127_2408315_3	485913.Krac_4443	2.368e-103	343.0	COG1028@1|root,COG1028@2|Bacteria,2G7U1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
GZD3_k127_2408315_0	926550.CLDAP_25170	6.514e-159	514.0	COG0596@1|root,COG0596@2|Bacteria,2GA9B@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_2409134_4	1122228.AQXR01000009_gene1264	6.879e-08	60.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GZD3_k127_2409134_0	1382306.JNIM01000001_gene444	1.863e-70	248.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
GZD3_k127_2409134_1	485913.Krac_8405	8.365e-63	224.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2409134_3	316274.Haur_2247	5.042e-09	64.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_2412879_1	649638.Trad_2349	8.972e-247	775.0	COG1132@1|root,COG1132@2|Bacteria,1WIMR@1297|Deinococcus-Thermus	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	yknV	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_2412879_2	649638.Trad_2350	3.453e-228	721.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_2412879_0	479434.Sthe_2668	0.0	1343.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GZD3_k127_2412879_4	298655.KI912267_gene7659	1.853e-10	71.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_2412879_3	436229.JOEH01000051_gene6274	1.889e-168	552.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria	201174|Actinobacteria	T	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GZD3_k127_2413961_1	526227.Mesil_0060	6.979e-135	441.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_2413961_0	485913.Krac_3296	2.149e-144	467.0	COG0809@1|root,COG0809@2|Bacteria,2G7UA@200795|Chloroflexi	200795|Chloroflexi	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
GZD3_k127_2413961_2	485913.Krac_8762	5.549e-111	366.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_2414863_0	479434.Sthe_1376	4.075e-19	95.0	COG1670@1|root,COG1670@2|Bacteria,2G9BF@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
GZD3_k127_2414863_2	935840.JAEQ01000003_gene93	7.747e-15	80.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,2UU7U@28211|Alphaproteobacteria,43RH9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
GZD3_k127_2414863_3	395963.Bind_0635	1.482e-05	58.0	COG3740@1|root,COG3740@2|Bacteria,1RBZM@1224|Proteobacteria,2U6PG@28211|Alphaproteobacteria,3NB12@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Phage prohead protease, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2414863_1	208444.JNYY01000027_gene6128	7.023e-17	93.0	28H58@1|root,2Z7HV@2|Bacteria,2GWVU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2415497_4	316274.Haur_3068	4.518e-37	156.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	2|Bacteria	KLT	SMART tyrosine protein kinase	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
GZD3_k127_2415497_7	1128421.JAGA01000003_gene2930	4.126e-29	125.0	2CDDX@1|root,3058G@2|Bacteria	2|Bacteria	E	Alkylmercury lyase	merB	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB
GZD3_k127_2415497_8	196162.Noca_4945	9.093e-28	119.0	COG0789@1|root,COG0789@2|Bacteria,2IPUM@201174|Actinobacteria,4DVDB@85009|Propionibacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GZD3_k127_2415497_1	1128421.JAGA01000003_gene2935	3.01e-159	516.0	COG1249@1|root,COG1249@2|Bacteria,2NQD5@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	HMA,Pyr_redox_2,Pyr_redox_dim
GZD3_k127_2415497_5	1382306.JNIM01000001_gene2016	6.069e-37	144.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GZD3_k127_2415497_0	479434.Sthe_0130	1.926e-159	512.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_2415497_3	485913.Krac_10871	3.331e-80	278.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
GZD3_k127_2415497_6	1449063.JMLS01000002_gene1333	1.554e-30	128.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
GZD3_k127_2415497_2	682795.AciX8_0629	2.621e-157	505.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
GZD3_k127_2415497_9	485913.Krac_3643	5.969e-20	91.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi	200795|Chloroflexi	C	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
GZD3_k127_242152_5	1385511.N783_00400	2.914e-18	98.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_242152_3	479434.Sthe_0049	2.687e-74	257.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,27Z60@189775|Thermomicrobia	189775|Thermomicrobia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GZD3_k127_242152_2	357808.RoseRS_4217	1.85e-82	288.0	COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi,37752@32061|Chloroflexia	32061|Chloroflexia	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GZD3_k127_242152_1	525904.Tter_0152	1.561e-96	321.0	COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_242152_0	1128421.JAGA01000003_gene2762	2.708e-132	427.0	COG1215@1|root,COG1215@2|Bacteria,2NQUC@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	rfbN	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
GZD3_k127_242152_4	479434.Sthe_0047	3.663e-62	217.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,27Z3S@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_2423903_0	383372.Rcas_1030	1.321e-80	276.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi,377XR@32061|Chloroflexia	32061|Chloroflexia	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GZD3_k127_2423903_1	1382306.JNIM01000001_gene2933	1.658e-49	203.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
GZD3_k127_2424490_2	309801.trd_1809	4.559e-32	137.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_2424490_0	1151122.AQYD01000007_gene208	3.772e-129	437.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4FMN0@85023|Microbacteriaceae	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
GZD3_k127_2424490_1	485913.Krac_7240	1.145e-41	167.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_2424490_3	324602.Caur_2527	1.351e-18	96.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_2428420_0	1121377.KB906399_gene1656	2.95e-37	158.0	COG0387@1|root,COG0387@2|Bacteria,1WJIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GZD3_k127_2431461_17	1120973.AQXL01000115_gene664	6.317e-11	70.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2431461_3	1382306.JNIM01000001_gene3378	6.054e-101	337.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
GZD3_k127_2431461_2	485913.Krac_2548	4.823e-110	362.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
GZD3_k127_2431461_8	1005395.CSV86_15225	7.42e-55	203.0	COG0765@1|root,COG0765@2|Bacteria,1PGSY@1224|Proteobacteria,1T9FZ@1236|Gammaproteobacteria,1YWRE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
GZD3_k127_2431461_10	485913.Krac_1375	1.633e-48	193.0	COG0834@1|root,COG0834@2|Bacteria,2G7BD@200795|Chloroflexi	200795|Chloroflexi	ET	COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
GZD3_k127_2431461_18	402777.KB235898_gene5364	2.554e-09	60.0	COG1724@1|root,COG1724@2|Bacteria,1G8YW@1117|Cyanobacteria,1HD4D@1150|Oscillatoriales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_2431461_16	329726.AM1_6129	7.527e-13	71.0	COG1598@1|root,COG1598@2|Bacteria,1G8ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_2431461_15	479431.Namu_4216	6.169e-20	100.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GZD3_k127_2431461_0	485913.Krac_4895	1.409e-132	435.0	COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi	2|Bacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_2431461_5	749414.SBI_00138	8.671e-86	299.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_2431461_11	485913.Krac_8552	4.457e-46	179.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2431461_20	518766.Rmar_2225	0.0002018	52.0	COG5660@1|root,COG5660@2|Bacteria,4PF9I@976|Bacteroidetes,1FKBP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
GZD3_k127_2431461_13	1382306.JNIM01000001_gene389	1.468e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,2G95I@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2431461_21	485913.Krac_5405	0.0003981	53.0	2CC95@1|root,2Z8VE@2|Bacteria,2G92N@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2431461_7	1128421.JAGA01000004_gene2645	5e-59	232.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	wgeF	-	-	-	-	-	-	-	-	-	-	-	GT87,Glycos_transf_2
GZD3_k127_2431461_1	1303518.CCALI_01587	1.4e-119	402.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
GZD3_k127_2431461_9	1303518.CCALI_01588	1.206e-48	185.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
GZD3_k127_2431461_4	1382306.JNIM01000001_gene723	4.132e-87	299.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GZD3_k127_2431461_12	485913.Krac_8262	2.601e-45	175.0	COG1647@1|root,COG1647@2|Bacteria,2G73V@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
GZD3_k127_2436552_0	1121468.AUBR01000028_gene1527	2.9e-135	445.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42I2K@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_2436552_2	398578.Daci_1595	3.213e-24	109.0	COG1120@1|root,COG2453@1|root,COG1120@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae	28216|Betaproteobacteria	HPT	PFAM Dual specificity protein phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	ABC_tran,DSPc
GZD3_k127_2436552_3	56107.Cylst_1408	8.235e-24	107.0	COG2402@1|root,COG2402@2|Bacteria,1GQ8N@1117|Cyanobacteria,1HTP0@1161|Nostocales	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GZD3_k127_2436552_1	525904.Tter_0425	3.865e-115	377.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
GZD3_k127_2445787_6	1382306.JNIM01000001_gene3613	5.274e-112	373.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GZD3_k127_2445787_2	485913.Krac_8281	7.172e-163	528.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GZD3_k127_2445787_1	1382306.JNIM01000001_gene3611	1.86e-182	594.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GZD3_k127_2445787_21	1382306.JNIM01000001_gene3610	2.062e-31	126.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GZD3_k127_2445787_19	485913.Krac_8284	2.206e-40	164.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD3_k127_2445787_0	518766.Rmar_1062	3.538e-189	606.0	COG0146@1|root,COG0146@2|Bacteria,4PM5E@976|Bacteroidetes,1FJR8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
GZD3_k127_2445787_28	1306174.JODP01000013_gene7486	6.841e-10	62.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2445787_29	744872.Spica_2397	5.461e-07	53.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
GZD3_k127_2445787_10	1265505.ATUG01000002_gene1740	2.561e-71	259.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	sarcosine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
GZD3_k127_2445787_5	485913.Krac_2308	1.098e-112	370.0	COG1595@1|root,COG1595@2|Bacteria,2G7NX@200795|Chloroflexi	2|Bacteria	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD3_k127_2445787_23	525368.HMPREF0591_2457	5.956e-20	97.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria,23AE5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_2445787_15	1150864.MILUP08_44290	2.047e-48	178.0	COG0346@1|root,COG0346@2|Bacteria,2IPQW@201174|Actinobacteria,4DM8J@85008|Micromonosporales	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_2445787_27	1121434.AULY01000008_gene127	7.469e-13	76.0	COG2350@1|root,COG2350@2|Bacteria,1RIMY@1224|Proteobacteria,4360T@68525|delta/epsilon subdivisions,2X0IC@28221|Deltaproteobacteria,2MCF6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2445787_25	1122222.AXWR01000017_gene2878	6.376e-17	89.0	COG2353@1|root,COG2353@2|Bacteria,1WMZ2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GZD3_k127_2445787_24	429009.Adeg_1337	2.369e-17	87.0	COG1487@1|root,COG1487@2|Bacteria,1VKMK@1239|Firmicutes,25DTE@186801|Clostridia	186801|Clostridia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GZD3_k127_2445787_4	485913.Krac_4861	2.115e-121	400.0	COG1878@1|root,COG1878@2|Bacteria,2G6WM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
GZD3_k127_2445787_18	485913.Krac_12090	6.878e-41	162.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2778,PG_binding_1,YkuD
GZD3_k127_2445787_9	272134.KB731324_gene3351	3.616e-72	250.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,1HAP9@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
GZD3_k127_2445787_17	756499.Desde_3240	1.516e-41	156.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
GZD3_k127_2445787_3	1324957.K933_11936	3.348e-138	456.0	COG0624@1|root,arCOG01107@2157|Archaea,2XU86@28890|Euryarchaeota,23ST7@183963|Halobacteria	183963|Halobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD3_k127_2445787_26	396588.Tgr7_0732	1.729e-14	84.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1WXKK@135613|Chromatiales	135613|Chromatiales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
GZD3_k127_2445787_16	204669.Acid345_1110	1.119e-42	168.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
GZD3_k127_2445787_14	479434.Sthe_1369	3.234e-51	192.0	COG1598@1|root,COG2318@1|root,COG1598@2|Bacteria,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
GZD3_k127_2445787_30	1394178.AWOO02000020_gene7393	0.0002269	53.0	2E89B@1|root,332N6@2|Bacteria,2IMU0@201174|Actinobacteria,4EKDH@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2445787_7	485913.Krac_8705	1.673e-107	362.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
GZD3_k127_2445787_13	1462527.CCDM010000002_gene1513	3.067e-58	214.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
GZD3_k127_2445787_22	1121926.AXWO01000008_gene2943	5.366e-27	116.0	2E36Z@1|root,32Y6R@2|Bacteria,2IPME@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
GZD3_k127_2445787_8	575540.Isop_2405	5.806e-99	331.0	COG0614@1|root,COG0614@2|Bacteria,2IXWX@203682|Planctomycetes	203682|Planctomycetes	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GZD3_k127_2445787_12	485913.Krac_9745	2.293e-63	228.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_24466_0	485913.Krac_11995	1.43e-189	598.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
GZD3_k127_24466_1	926550.CLDAP_01660	4.557e-76	269.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_2446660_1	1173026.Glo7428_2094	2.794e-127	429.0	COG0642@1|root,COG0784@1|root,COG2197@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
GZD3_k127_2446660_0	1382306.JNIM01000001_gene1186	0.0	1022.0	COG0243@1|root,COG0243@2|Bacteria,2G7V5@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
GZD3_k127_2452065_0	235985.BBPN01000077_gene7066	8.834e-183	588.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria,2NKAJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_5	1382306.JNIM01000001_gene3515	7.423e-106	353.0	COG0010@1|root,COG0010@2|Bacteria,2G5N5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GZD3_k127_24535_4	1382306.JNIM01000001_gene39	1.573e-106	355.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
GZD3_k127_24535_2	485913.Krac_12300	2.451e-109	366.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_24535_15	485913.Krac_12301	4.382e-24	114.0	29XJT@1|root,30JAV@2|Bacteria,2G9T6@200795|Chloroflexi	485913.Krac_12301|-	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_11	1340434.AXVA01000027_gene1044	6.287e-41	160.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE,SfLAP
GZD3_k127_24535_1	1382306.JNIM01000001_gene13	3.161e-118	390.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
GZD3_k127_24535_6	326427.Cagg_3187	1.038e-93	320.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi,376U9@32061|Chloroflexia	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_24535_14	485913.Krac_8683	7.343e-31	137.0	COG0745@1|root,COG0745@2|Bacteria,2G9KD@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_24535_13	1122603.ATVI01000005_gene3528	1.72e-32	138.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RXZ5@1236|Gammaproteobacteria,1X4RH@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	rbcR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
GZD3_k127_24535_12	292459.STH1555	8.797e-37	154.0	COG0346@1|root,COG0346@2|Bacteria,1VAEF@1239|Firmicutes,252DK@186801|Clostridia	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_10	479434.Sthe_1958	3.134e-73	262.0	COG0500@1|root,COG2226@2|Bacteria,2G6R0@200795|Chloroflexi,27Z68@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_24535_8	211165.AJLN01000114_gene5953	1.632e-76	267.0	COG0500@1|root,COG2226@2|Bacteria,1G4JN@1117|Cyanobacteria,1JJFD@1189|Stigonemataceae	1117|Cyanobacteria	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD3_k127_24535_20	867845.KI911784_gene2617	2.517e-08	65.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,375CV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_3	1382306.JNIM01000001_gene4220	4.058e-109	375.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
GZD3_k127_24535_16	1382306.JNIM01000001_gene632	1.704e-20	96.0	COG3729@1|root,COG3729@2|Bacteria	2|Bacteria	D	General stress protein	gsiB	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	AHH,KGG,LEA_5,YjzC
GZD3_k127_24535_21	1435356.Y013_23410	2.68e-05	53.0	2ENMM@1|root,33G8Y@2|Bacteria,2H5W8@201174|Actinobacteria,4G3EM@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_9	263820.PTO1106	1.77e-75	265.0	COG1192@1|root,arCOG00586@2157|Archaea,2Y67X@28890|Euryarchaeota,242CK@183967|Thermoplasmata	183967|Thermoplasmata	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD3_k127_24535_19	1385521.N803_14150	2.703e-10	70.0	COG0343@1|root,COG1598@1|root,COG0343@2|Bacteria,COG1598@2|Bacteria,2IQDG@201174|Actinobacteria	201174|Actinobacteria	J	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_24535_7	1270196.JCKI01000010_gene818	3.396e-80	276.0	COG3617@1|root,COG3617@2|Bacteria,4NIG0@976|Bacteroidetes	976|Bacteroidetes	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
GZD3_k127_24535_0	485913.Krac_8287	6.562e-244	771.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GZD3_k127_2454425_4	644966.Tmar_2266	8.635e-28	120.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WCG3@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
GZD3_k127_2454425_2	1120936.KB907222_gene2290	3.356e-41	171.0	2D44J@1|root,32TG9@2|Bacteria,2I3U2@201174|Actinobacteria,4EJKY@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2454425_5	471852.Tcur_1870	3.249e-22	113.0	2EW2P@1|root,33PFY@2|Bacteria,2GMVZ@201174|Actinobacteria,4EKCM@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2454425_1	1230342.CTM_01754	7.66e-74	263.0	COG0699@1|root,COG0699@2|Bacteria,1UID1@1239|Firmicutes,24AJ9@186801|Clostridia,36HVZ@31979|Clostridiaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2454425_3	543632.JOJL01000002_gene8175	9.079e-35	155.0	COG3468@1|root,COG3468@2|Bacteria,2I58W@201174|Actinobacteria,4DKQY@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2454425_0	886293.Sinac_1818	1.725e-166	548.0	COG0443@1|root,COG2304@1|root,COG0443@2|Bacteria,COG2304@2|Bacteria,2IWUQ@203682|Planctomycetes	203682|Planctomycetes	O	heat shock protein 70	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,VWA
GZD3_k127_2454425_6	1123499.KB908018_gene2026	0.0004082	44.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KPV9@206351|Neisseriales	206351|Neisseriales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
GZD3_k127_2458321_0	234267.Acid_1182	5.62e-235	734.0	COG0076@1|root,COG0076@2|Bacteria,3Y2SW@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
GZD3_k127_2458321_2	324602.Caur_0653	2.725e-53	193.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
GZD3_k127_2458321_1	479434.Sthe_2979	8.154e-123	401.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,27YFG@189775|Thermomicrobia	189775|Thermomicrobia	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
GZD3_k127_2458321_3	479434.Sthe_1581	4.57e-14	72.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD3_k127_2458871_2	621372.ACIH01000217_gene1082	3.881e-28	117.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,26T4Z@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
GZD3_k127_2458871_0	485913.Krac_0300	5.843e-82	293.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_2458871_1	485913.Krac_0300	1.256e-69	256.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_2465379_5	1120934.KB894422_gene2901	7.966e-27	124.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4E6Z1@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2465379_4	485913.Krac_10312	1.963e-78	271.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi	200795|Chloroflexi	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
GZD3_k127_2465379_2	1041147.AUFB01000019_gene5509	1.355e-169	540.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2TSCE@28211|Alphaproteobacteria,4B88J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_2465379_3	1283283.ATXA01000003_gene1597	5.047e-129	422.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,4EUSR@85013|Frankiales	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	dipZ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
GZD3_k127_2465379_0	1121127.JAFA01000046_gene6827	5.549e-215	675.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2VZP3@28216|Betaproteobacteria,1KHJR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GZD3_k127_2465379_1	1211777.BN77_3261	3.275e-201	631.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,4B7GV@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
GZD3_k127_2470272_0	1463854.JOHT01000019_gene4767	4.464e-177	564.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
GZD3_k127_2470272_1	448385.sce7410	3.963e-30	123.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,43A9U@68525|delta/epsilon subdivisions,2X244@28221|Deltaproteobacteria,2Z171@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:RRM_6	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GZD3_k127_2470272_2	1236501.BAJU01000001_gene267	0.0006339	46.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2JQ5V@204441|Rhodospirillales	204441|Rhodospirillales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GZD3_k127_2470584_3	1382306.JNIM01000001_gene377	2.709e-65	224.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GZD3_k127_2470584_6	1121385.AQXW01000004_gene2426	1.077e-16	86.0	COG0454@1|root,COG0456@2|Bacteria,2GMXI@201174|Actinobacteria	201174|Actinobacteria	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_2470584_7	340.xcc-b100_3123	8.502e-15	85.0	COG0457@1|root,COG0457@2|Bacteria,1NY1N@1224|Proteobacteria,1SEPN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
GZD3_k127_2470584_5	479434.Sthe_2065	3.102e-25	117.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
GZD3_k127_2470584_1	1304880.JAGB01000003_gene1148	6.73e-95	321.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N,NTP_transferase
GZD3_k127_2470584_2	1382306.JNIM01000001_gene1709	1.434e-89	303.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_2470584_4	590998.Celf_0271	3.457e-43	173.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4F270@85016|Cellulomonadaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GZD3_k127_2470584_0	1034769.KB910518_gene3948	8.539e-141	460.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HF1P@91061|Bacilli,26R7P@186822|Paenibacillaceae	91061|Bacilli	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GZD3_k127_2485204_22	1247024.JRLH01000001_gene1010	0.0001533	51.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2485204_20	1229780.BN381_490014	3.984e-07	57.0	COG1357@1|root,COG1357@2|Bacteria,2GNJ9@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
GZD3_k127_2485204_14	745776.DGo_PC0065	2.785e-34	138.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GZD3_k127_2485204_19	745776.DGo_PC0065	2.992e-11	70.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
GZD3_k127_2485204_1	485913.Krac_2115	3.66e-117	387.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD3_k127_2485204_6	1444309.JAQG01000017_gene720	4.636e-72	254.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,26QA7@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	iYO844.BSU02360	Glucosamine_iso
GZD3_k127_2485204_0	319795.Dgeo_2622	2.862e-122	416.0	COG1080@1|root,COG1080@2|Bacteria,1WJ4Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
GZD3_k127_2485204_17	644966.Tmar_2035	9.795e-18	89.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WDM8@538999|Clostridiales incertae sedis	186801|Clostridia	G	PFAM PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
GZD3_k127_2485204_7	358681.BBR47_44880	3.459e-69	251.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,26RVP@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443,ko:K16786,ko:K16787	ko00520,ko01130,ko02010,map00520,map01130,map02010	M00582	R02059	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Amidohydro_1
GZD3_k127_2485204_4	485913.Krac_8142	5.303e-87	294.0	COG4821@1|root,COG4821@2|Bacteria,2G9A3@200795|Chloroflexi	2|Bacteria	S	protein containing SIS (Sugar ISomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
GZD3_k127_2485204_11	1121024.AUCD01000008_gene2102	2.1e-46	178.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli	91061|Bacilli	S	protein containing SIS (Sugar ISomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
GZD3_k127_2485204_8	292459.STH1938	2.849e-59	222.0	COG3356@1|root,COG3356@2|Bacteria,1V8FN@1239|Firmicutes,25EZV@186801|Clostridia	186801|Clostridia	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2485204_9	292459.STH1939	8.614e-56	200.0	COG3444@1|root,COG3444@2|Bacteria,1UZRR@1239|Firmicutes,24G18@186801|Clostridia	186801|Clostridia	G	system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
GZD3_k127_2485204_15	485913.Krac_9831	1.153e-32	131.0	COG2893@1|root,COG2893@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
GZD3_k127_2485204_2	1356854.N007_09065	9.94e-103	344.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli	91061|Bacilli	G	PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
GZD3_k127_2485204_5	1356854.N007_09070	5.432e-84	287.0	COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HFQS@91061|Bacilli	91061|Bacilli	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
GZD3_k127_2485204_10	1132442.KB889752_gene1880	2.735e-54	200.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GZD3_k127_2485204_3	479434.Sthe_0632	7.911e-102	341.0	COG0122@1|root,COG0122@2|Bacteria,2G8TI@200795|Chloroflexi,27YWG@189775|Thermomicrobia	189775|Thermomicrobia	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GZD3_k127_2485204_12	485913.Krac_1496	2.267e-39	150.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GZD3_k127_2485204_16	714943.Mucpa_1190	1.151e-23	111.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IX0Z@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GZD3_k127_2485204_18	179408.Osc7112_1799	4.822e-14	76.0	COG1308@1|root,COG1308@2|Bacteria,1G83N@1117|Cyanobacteria,1HC9J@1150|Oscillatoriales	1117|Cyanobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
GZD3_k127_2485204_21	1123276.KB893251_gene3667	3.517e-06	51.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,47M24@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
GZD3_k127_2489231_2	1382306.JNIM01000001_gene1509	1.607e-129	427.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
GZD3_k127_2489231_0	485913.Krac_8056	8.819e-160	524.0	COG0726@1|root,COG0726@2|Bacteria,2G8HZ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD3_k127_2489231_1	485913.Krac_4222	1.908e-158	516.0	COG1749@1|root,COG4409@1|root,COG1749@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ASH,DUF4082,Flg_bb_rod,Flg_bbr_C
GZD3_k127_2498686_8	485913.Krac_0462	9.333e-14	74.0	COG0675@1|root,COG0675@2|Bacteria,2G89V@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_2498686_2	485913.Krac_0705	7.911e-138	447.0	COG0675@1|root,COG0675@2|Bacteria,2G89V@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_2498686_9	546414.Deide_18490	0.0005459	51.0	2EF7V@1|root,3390U@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1282,Yip1
GZD3_k127_2498686_3	1382306.JNIM01000001_gene381	1.333e-97	347.0	COG3372@1|root,COG3372@2|Bacteria,2G9BS@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
GZD3_k127_2498686_1	1382306.JNIM01000001_gene379	3.451e-164	530.0	COG1061@1|root,COG1061@2|Bacteria,2G7QW@200795|Chloroflexi	200795|Chloroflexi	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
GZD3_k127_2498686_6	1382306.JNIM01000001_gene3082	5.055e-51	192.0	COG1211@1|root,COG1211@2|Bacteria	2|Bacteria	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
GZD3_k127_2498686_5	485913.Krac_2799	1.871e-58	210.0	COG0780@1|root,COG0780@2|Bacteria,2G9AQ@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
GZD3_k127_2498686_7	443143.GM18_1347	3.931e-28	124.0	COG1082@1|root,COG1082@2|Bacteria,1RGEK@1224|Proteobacteria,42S9K@68525|delta/epsilon subdivisions,2WNFH@28221|Deltaproteobacteria,43TC8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
GZD3_k127_2498686_0	1382306.JNIM01000001_gene1634	4.117e-175	562.0	COG0174@1|root,COG0174@2|Bacteria,2G62E@200795|Chloroflexi	200795|Chloroflexi	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
GZD3_k127_2503969_3	1051632.TPY_0862	5.951e-113	370.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WCEN@538999|Clostridiales incertae sedis	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hymB	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
GZD3_k127_2503969_0	1382306.JNIM01000001_gene3466	6.167e-264	837.0	COG3383@1|root,COG3383@2|Bacteria,2G65S@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
GZD3_k127_2503969_2	1382306.JNIM01000001_gene3465	4.314e-146	473.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GZD3_k127_2503969_4	485913.Krac_9049	2.768e-89	304.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
GZD3_k127_2503969_5	1382306.JNIM01000001_gene3463	1.163e-40	160.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
GZD3_k127_2503969_6	485913.Krac_9052	1.316e-37	144.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
GZD3_k127_2503969_1	1382306.JNIM01000001_gene3461	1.095e-187	605.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
GZD3_k127_2510583_4	1379858.N508_01010	1.447e-38	161.0	COG0475@1|root,COG0475@2|Bacteria,2GFD1@200930|Deferribacteres	200930|Deferribacteres	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GZD3_k127_2510583_2	479434.Sthe_1763	5.902e-103	342.0	COG1024@1|root,COG1024@2|Bacteria,2G6BP@200795|Chloroflexi,27XR0@189775|Thermomicrobia	189775|Thermomicrobia	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GZD3_k127_2510583_1	404589.Anae109_1311	1.124e-128	439.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GZD3_k127_2510583_0	1382306.JNIM01000001_gene121	1.349e-189	625.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
GZD3_k127_2510583_3	1382306.JNIM01000001_gene81	1.302e-77	281.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GZD3_k127_2510583_5	1382306.JNIM01000001_gene1437	2.055e-29	119.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
GZD3_k127_2511498_0	485913.Krac_0300	1.763e-89	320.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_2511498_1	485913.Krac_2399	2.137e-19	94.0	COG4291@1|root,COG4291@2|Bacteria	2|Bacteria	C	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
GZD3_k127_2512289_1	397278.JOJN01000017_gene2529	0.0004583	52.0	2ASGX@1|root,31HX4@2|Bacteria,2IJVE@201174|Actinobacteria,4DQUB@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2512289_0	1382306.JNIM01000001_gene861	2.37e-84	282.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GZD3_k127_2523301_7	1476583.DEIPH_ctg033orf0033	2.914e-33	134.0	COG0161@1|root,COG0161@2|Bacteria,1WM0W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GZD3_k127_2523301_4	378806.STAUR_3066	1.105e-49	188.0	COG0223@1|root,COG0223@2|Bacteria,1Q4RD@1224|Proteobacteria,4347V@68525|delta/epsilon subdivisions,2X1ZP@28221|Deltaproteobacteria,2YZPA@29|Myxococcales	28221|Deltaproteobacteria	J	Formyl transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N
GZD3_k127_2523301_10	368407.Memar_1245	2.526e-17	82.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y1KD@28890|Euryarchaeota	28890|Euryarchaeota	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_2523301_2	1382306.JNIM01000001_gene1888	1.266e-93	317.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
GZD3_k127_2523301_0	552811.Dehly_1121	2.323e-113	375.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
GZD3_k127_2523301_5	479434.Sthe_3033	9.969e-48	179.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
GZD3_k127_2523301_1	1382306.JNIM01000001_gene4028	4.196e-108	359.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
GZD3_k127_2523301_8	292459.STH2289	3.036e-19	94.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_2523301_9	552811.Dehly_0264	5.476e-19	98.0	COG3328@1|root,COG3328@2|Bacteria,2G6SX@200795|Chloroflexi,34DPA@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_2523301_6	867903.ThesuDRAFT_01114	1.167e-46	175.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_2546094_0	1382306.JNIM01000001_gene1160	5.373e-88	297.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
GZD3_k127_2546094_2	518766.Rmar_2432	2.57e-19	89.0	2A1D2@1|root,30PK3@2|Bacteria,4NW4I@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
GZD3_k127_2546094_3	485913.Krac_11125	6.106e-17	84.0	COG1977@1|root,COG1977@2|Bacteria,2G9JN@200795|Chloroflexi	200795|Chloroflexi	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
GZD3_k127_2546094_1	1382306.JNIM01000001_gene1158	1.716e-25	109.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
GZD3_k127_2548149_0	485913.Krac_10686	2.897e-64	225.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2G82S@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A7NFQ2 Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_2548149_1	102129.Lepto7375DRAFT_1633	2.173e-20	92.0	COG0863@1|root,COG0863@2|Bacteria,1G2W1@1117|Cyanobacteria,1HHNQ@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_2548149_3	1348663.KCH_58830	0.0003341	44.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GZD3_k127_2548149_2	635013.TherJR_0594	4.932e-06	59.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,2630X@186807|Peptococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
GZD3_k127_2550368_0	485913.Krac_3932	2.533e-94	327.0	2FB93@1|root,343F8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
GZD3_k127_2550368_2	670487.Ocepr_1560	3.745e-28	121.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269,HIT
GZD3_k127_2550368_1	485913.Krac_4041	4.8e-29	128.0	COG0537@1|root,COG0607@1|root,COG4283@1|root,COG0537@2|Bacteria,COG0607@2|Bacteria,COG4283@2|Bacteria,2G8I6@200795|Chloroflexi	200795|Chloroflexi	KP	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Rhodanese
GZD3_k127_2561000_3	316274.Haur_2430	1.857e-57	207.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_2561000_0	266117.Rxyl_2822	6.992e-94	322.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4CPI4@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
GZD3_k127_2561000_7	68223.JNZY01000010_gene1858	0.0004976	51.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GJSK@201174|Actinobacteria	201174|Actinobacteria	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,PAS_3,PAS_4,SpoIIE
GZD3_k127_2561000_5	1382306.JNIM01000001_gene632	5.459e-20	95.0	COG3729@1|root,COG3729@2|Bacteria	2|Bacteria	D	General stress protein	gsiB	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	AHH,KGG,LEA_5,YjzC
GZD3_k127_2561000_1	1521187.JPIM01000148_gene3777	1.655e-86	301.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,375XV@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ornithine cyclodeaminase mu-crystallin	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GZD3_k127_2561000_2	99598.Cal7507_3986	1.408e-76	286.0	COG3903@1|root,COG3903@2|Bacteria,1G5J8@1117|Cyanobacteria,1HMYS@1161|Nostocales	1117|Cyanobacteria	K	PFAM NB-ARC domain	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16
GZD3_k127_2561000_6	1382306.JNIM01000001_gene3493	3.026e-12	75.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD3_k127_2575493_5	671143.DAMO_1000	9.855e-71	243.0	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
GZD3_k127_2575493_20	263358.VAB18032_03920	1.21e-06	56.0	COG3631@1|root,COG3631@2|Bacteria,2HV03@201174|Actinobacteria,4DGFE@85008|Micromonosporales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GZD3_k127_2575493_7	1382306.JNIM01000001_gene258	1.191e-63	228.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
GZD3_k127_2575493_2	1382306.JNIM01000001_gene257	1.766e-145	485.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
GZD3_k127_2575493_10	1382306.JNIM01000001_gene256	2.022e-37	145.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi	200795|Chloroflexi	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
GZD3_k127_2575493_6	1283299.AUKG01000001_gene1742	2.944e-64	236.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD3_k127_2575493_0	1382306.JNIM01000001_gene3872	8.247e-205	654.0	COG1387@1|root,COG1387@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
GZD3_k127_2575493_4	485913.Krac_5186	1.014e-117	385.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GZD3_k127_2575493_3	1382306.JNIM01000001_gene2685	9.807e-135	444.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
GZD3_k127_2575493_14	309801.trd_1322	2.263e-25	112.0	COG1846@1|root,COG1846@2|Bacteria,2G97N@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2575493_12	1123020.AUIE01000043_gene1734	5.262e-31	132.0	COG0491@1|root,COG0491@2|Bacteria,1N6PM@1224|Proteobacteria,1RY36@1236|Gammaproteobacteria,1YEB6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_2575493_15	395961.Cyan7425_1718	2.549e-19	94.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2575493_11	485913.Krac_2373	1.244e-36	142.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD3_k127_2575493_16	413816.BBJP01000017_gene1218	5.932e-18	97.0	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,23SN7@183963|Halobacteria	183963|Halobacteria	S	COG1078 HD superfamily phosphohydrolases	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
GZD3_k127_2575493_18	586416.GZ22_13335	3.151e-07	63.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	tlpC	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_3_3
GZD3_k127_2575493_9	485913.Krac_10933	4.072e-38	152.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
GZD3_k127_2575493_13	479434.Sthe_2183	6.807e-30	126.0	COG1547@1|root,COG1547@2|Bacteria,2GAFU@200795|Chloroflexi,27YQW@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
GZD3_k127_2575493_8	649638.Trad_1717	6.639e-59	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD3_k127_2575493_1	1382306.JNIM01000001_gene3396	5.878e-186	587.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
GZD3_k127_2583065_0	266117.Rxyl_1289	5.306e-65	225.0	COG2030@1|root,COG2030@2|Bacteria,2GWI8@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GZD3_k127_2583065_1	485913.Krac_9163	1.276e-30	122.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
GZD3_k127_2585343_4	266117.Rxyl_2910	3.147e-36	139.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
GZD3_k127_2585343_1	485913.Krac_9414	1.64e-75	265.0	COG1305@1|root,COG1305@2|Bacteria,2G8MP@200795|Chloroflexi	200795|Chloroflexi	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
GZD3_k127_2585343_3	1042163.BRLA_c005200	1.233e-49	180.0	COG1943@1|root,COG1943@2|Bacteria,1V608@1239|Firmicutes,4HMRP@91061|Bacilli,26XW9@186822|Paenibacillaceae	91061|Bacilli	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD3_k127_2585343_0	326427.Cagg_3187	1.309e-93	320.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi,376U9@32061|Chloroflexia	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_2585343_2	926560.KE387027_gene352	5.628e-55	204.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1WMXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2596550_0	1382306.JNIM01000001_gene2853	0.0	1038.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi	200795|Chloroflexi	T	PrkA AAA domain protein	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
GZD3_k127_2596550_4	1259795.ARJK01000002_gene414	3.043e-60	217.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,24BBC@186801|Clostridia,42GNP@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG4	-	1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76	ko:K00059,ko:K18009,ko:K19548	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R10917,R11671	RC00029,RC00117,RC00154,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_2596550_1	1382306.JNIM01000001_gene3272	1.631e-136	455.0	COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD3_k127_2596550_5	1121272.KB903249_gene2255	1.65e-43	164.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
GZD3_k127_2596550_3	243233.MCA2600	9.772e-66	252.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XEBD@135618|Methylococcales	135618|Methylococcales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
GZD3_k127_2596550_6	485913.Krac_5098	4.889e-40	152.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_2596550_9	234267.Acid_4838	0.0008199	48.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
GZD3_k127_2596550_7	398767.Glov_2275	1.776e-36	149.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
GZD3_k127_2596550_8	68194.JNXR01000015_gene8081	1.124e-15	87.0	COG2340@1|root,COG2340@2|Bacteria,2I39U@201174|Actinobacteria	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
GZD3_k127_2596550_2	485913.Krac_2308	2.38e-80	274.0	COG1595@1|root,COG1595@2|Bacteria,2G7NX@200795|Chloroflexi	2|Bacteria	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD3_k127_2597799_0	1521187.JPIM01000074_gene2858	1.231e-111	373.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,375H2@32061|Chloroflexia	32061|Chloroflexia	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_2605034_2	485913.Krac_8169	1.015e-79	288.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GZD3_k127_2605034_1	1123024.AUII01000021_gene11	8.452e-108	356.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4E3S9@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
GZD3_k127_2605034_0	1068980.ARVW01000001_gene7443	4.686e-115	378.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2605034_3	1382306.JNIM01000001_gene3681	7.094e-74	258.0	COG1695@1|root,COG1695@2|Bacteria,2G9N5@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
GZD3_k127_2605034_8	1122138.AQUZ01000029_gene4783	1.224e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4DRSB@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_2605034_6	1382306.JNIM01000001_gene1925	3.965e-40	156.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	ATP_bind_2,HIT
GZD3_k127_2605034_4	1382306.JNIM01000001_gene3877	1.69e-67	246.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
GZD3_k127_2605034_5	1128421.JAGA01000001_gene2054	4.535e-49	184.0	COG0491@1|root,COG0491@2|Bacteria,2NPD5@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GZD3_k127_2626198_0	1382306.JNIM01000001_gene3516	4.154e-137	445.0	COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
GZD3_k127_2626198_5	1365176.N186_08145	3.275e-23	102.0	COG1669@1|root,arCOG01206@2157|Archaea	2157|Archaea	M	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GZD3_k127_2626198_6	589924.Ferp_0438	1.675e-22	99.0	COG2361@1|root,arCOG05024@2157|Archaea,2Y6HF@28890|Euryarchaeota,246HB@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
GZD3_k127_2626198_2	864069.MicloDRAFT_00002920	1.151e-57	205.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
GZD3_k127_2626198_1	864069.MicloDRAFT_00027730	8.041e-69	243.0	COG3335@1|root,COG3335@2|Bacteria,1MXYQ@1224|Proteobacteria,2TSX4@28211|Alphaproteobacteria,1JYEX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GZD3_k127_2626198_7	861299.J421_5926	4.087e-13	75.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
GZD3_k127_2626198_8	208444.JNYY01000037_gene3996	5.3e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	208444.JNYY01000037_gene3996|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2626198_3	1380390.JIAT01000009_gene827	3.241e-51	205.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4CSVJ@84995|Rubrobacteria	84995|Rubrobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
GZD3_k127_2626198_9	1120949.KB903298_gene5660	9.768e-05	55.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DH36@85008|Micromonosporales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
GZD3_k127_2626198_4	1284352.AOIG01000017_gene4586	8.511e-42	165.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	yqiK	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GZD3_k127_2666764_2	1123024.AUII01000014_gene4295	2.401e-113	372.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria,4E2FP@85010|Pseudonocardiales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
GZD3_k127_2666764_8	1449347.JQLN01000007_gene1239	1.88e-73	252.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,2M65S@2063|Kitasatospora	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_2666764_0	1382306.JNIM01000001_gene219	1.464e-170	553.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
GZD3_k127_2666764_4	1382306.JNIM01000001_gene371	2.193e-103	371.0	COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_2666764_7	485913.Krac_2497	5.806e-87	312.0	2BI26@1|root,32C73@2|Bacteria,2G8JF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
GZD3_k127_2666764_13	935836.JAEL01000145_gene3216	8.306e-42	156.0	COG0640@1|root,COG0640@2|Bacteria,1VAMP@1239|Firmicutes,4HNAJ@91061|Bacilli,1ZGEP@1386|Bacillus	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
GZD3_k127_2666764_11	1329516.JPST01000061_gene1752	5.426e-65	231.0	COG3832@1|root,COG3832@2|Bacteria,1V5ZQ@1239|Firmicutes,4HGZ1@91061|Bacilli,27DAZ@186824|Thermoactinomycetaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD3_k127_2666764_6	485913.Krac_0667	2.004e-91	305.0	COG0262@1|root,COG0262@2|Bacteria,2G8UG@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_2666764_5	1278073.MYSTI_01573	3.075e-99	335.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD3_k127_2666764_10	485913.Krac_6736	3.985e-66	233.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
GZD3_k127_2666764_12	485913.Krac_6737	1.107e-47	182.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GZD3_k127_2666764_9	235985.BBPN01000077_gene7066	1.528e-68	255.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria,2NKAJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2666764_1	760568.Desku_1838	8.844e-149	486.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
GZD3_k127_2666764_3	1382306.JNIM01000001_gene4020	8.603e-105	368.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
GZD3_k127_2668149_1	485913.Krac_5405	2.882e-12	77.0	2CC95@1|root,2Z8VE@2|Bacteria,2G92N@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2668149_0	864702.OsccyDRAFT_1418	5.016e-63	221.0	COG0328@1|root,COG0328@2|Bacteria,1G5V5@1117|Cyanobacteria,1HH8G@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
GZD3_k127_2684384_2	1382306.JNIM01000001_gene689	1.315e-33	146.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GZD3_k127_2684384_1	383372.Rcas_0297	5.379e-67	239.0	COG4377@1|root,COG4377@2|Bacteria	2|Bacteria	S	Putative membrane peptidase family (DUF2324)	yhfC	-	-	-	-	-	-	-	-	-	-	-	DUF2324
GZD3_k127_2684384_0	1382306.JNIM01000001_gene3874	6.98e-146	479.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
GZD3_k127_2684384_4	1117647.M5M_05165	0.0009261	51.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1J6SG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0760 Parvulin-like peptidyl-prolyl isomerase	ppiC	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
GZD3_k127_2684384_3	1382306.JNIM01000001_gene846	8.982e-28	116.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
GZD3_k127_2687598_0	1340493.JNIF01000003_gene2606	1.633e-186	604.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
GZD3_k127_2687598_1	326427.Cagg_1231	4.827e-73	254.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
GZD3_k127_2687598_2	266117.Rxyl_2577	2.389e-20	92.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
GZD3_k127_2694383_0	1382306.JNIM01000001_gene1307	1.794e-142	456.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
GZD3_k127_2694383_1	667014.Thein_1874	3.466e-29	126.0	COG1586@1|root,COG1586@2|Bacteria,2GGST@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
GZD3_k127_269583_5	485913.Krac_7564	7.295e-35	138.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_7564|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_269583_3	1382306.JNIM01000001_gene986	1.972e-55	197.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	EAL,GGDEF,Glyco_tranf_2_3,PAS_7,Response_reg
GZD3_k127_269583_2	1382306.JNIM01000001_gene985	1.279e-96	334.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GZD3_k127_269583_1	1382306.JNIM01000001_gene981	2.069e-115	387.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi	200795|Chloroflexi	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
GZD3_k127_269583_0	1382306.JNIM01000001_gene980	5.686e-254	808.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GZD3_k127_269583_4	1382306.JNIM01000001_gene979	7.056e-54	198.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
GZD3_k127_271753_1	933262.AXAM01000022_gene3215	1.547e-115	384.0	COG1479@1|root,COG1479@2|Bacteria,1NRBC@1224|Proteobacteria,42VMR@68525|delta/epsilon subdivisions,2WSQN@28221|Deltaproteobacteria,2MMCV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
GZD3_k127_271753_0	357808.RoseRS_1479	0.0	1126.0	COG0553@1|root,COG0553@2|Bacteria,2G6I4@200795|Chloroflexi,376H9@32061|Chloroflexia	32061|Chloroflexia	KL	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2
GZD3_k127_2725881_0	1235279.C772_02041	7.24e-64	223.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,26D85@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
GZD3_k127_2725881_1	1254432.SCE1572_51280	1.581e-12	73.0	COG1734@1|root,COG1734@2|Bacteria,1N0ZH@1224|Proteobacteria,42Y1Y@68525|delta/epsilon subdivisions,2WT7K@28221|Deltaproteobacteria,2Z2R0@29|Myxococcales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GZD3_k127_2728084_23	404589.Anae109_0558	4.945e-28	124.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2WKS8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major facilitator superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
GZD3_k127_2728084_5	1382306.JNIM01000001_gene1476	8.586e-105	350.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_2728084_9	1382306.JNIM01000001_gene1477	3.622e-93	315.0	COG0411@1|root,COG0411@2|Bacteria,2G6GI@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD3_k127_2728084_2	1382306.JNIM01000001_gene1478	8.493e-112	372.0	COG4177@1|root,COG4177@2|Bacteria,2G8TP@200795|Chloroflexi	200795|Chloroflexi	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_2728084_3	1382306.JNIM01000001_gene1479	4.111e-108	360.0	COG0559@1|root,COG0559@2|Bacteria,2G8MW@200795|Chloroflexi	200795|Chloroflexi	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_2728084_0	1382306.JNIM01000001_gene1480	1.068e-164	529.0	COG0683@1|root,COG0683@2|Bacteria,2G6IY@200795|Chloroflexi	200795|Chloroflexi	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_2728084_12	525904.Tter_0922	1.852e-64	228.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
GZD3_k127_2728084_10	485913.Krac_7668	1.411e-85	297.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
GZD3_k127_2728084_14	479432.Sros_5396	2.103e-60	214.0	COG1670@1|root,COG1670@2|Bacteria,2IHXG@201174|Actinobacteria,4EN7J@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_2728084_13	1329516.JPST01000009_gene2087	5.457e-62	230.0	COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,4HI81@91061|Bacilli,27CTA@186824|Thermoactinomycetaceae	91061|Bacilli	Q	O-methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
GZD3_k127_2728084_4	485913.Krac_10963	4.783e-106	349.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
GZD3_k127_2728084_16	1382306.JNIM01000001_gene1257	6.63e-56	200.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
GZD3_k127_2728084_18	357808.RoseRS_3772	1.417e-37	149.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,3774D@32061|Chloroflexia	32061|Chloroflexia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
GZD3_k127_2728084_26	1144275.COCOR_05933	4.044e-10	68.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_2728084_29	349520.PPE_01167	0.0006042	51.0	COG1216@1|root,COG1216@2|Bacteria,1V01C@1239|Firmicutes,4HEIS@91061|Bacilli,26RPQ@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
GZD3_k127_2728084_6	316274.Haur_3300	5.157e-103	347.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_2728084_7	383372.Rcas_3107	5.741e-97	338.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_2728084_8	373994.Riv7116_3585	6.873e-97	329.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1HIYE@1161|Nostocales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
GZD3_k127_2728084_22	46234.ANA_C10381	1.838e-29	134.0	COG0438@1|root,COG0438@2|Bacteria,1G0TI@1117|Cyanobacteria,1HKVT@1161|Nostocales	1117|Cyanobacteria	M	SPTR Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
GZD3_k127_2728084_11	1128421.JAGA01000002_gene527	1.045e-81	291.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_2728084_24	1316927.ATKI01000120_gene3667	7.652e-23	116.0	COG2244@1|root,COG2244@2|Bacteria,1QS7T@1224|Proteobacteria,1RU3F@1236|Gammaproteobacteria,1YNMJ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
GZD3_k127_2728084_25	702113.PP1Y_AT21592	1.139e-10	74.0	COG0489@1|root,COG0489@2|Bacteria,1PDUC@1224|Proteobacteria,2U2MQ@28211|Alphaproteobacteria,2K065@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA
GZD3_k127_2728084_17	1382306.JNIM01000001_gene3428	3.075e-47	192.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,Pkinase,TIR_2,WD40
GZD3_k127_2728084_15	1094466.KQS_03480	2.084e-56	211.0	COG0500@1|root,COG0500@2|Bacteria,4NHEV@976|Bacteroidetes,1I055@117743|Flavobacteriia,2NTC1@237|Flavobacterium	976|Bacteroidetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD3_k127_2728084_19	272134.KB731324_gene3650	3.593e-36	150.0	COG0500@1|root,COG2226@2|Bacteria,1GCUU@1117|Cyanobacteria,1HEQW@1150|Oscillatoriales	1117|Cyanobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_2728084_1	485913.Krac_2049	2.903e-131	445.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_2728084_28	331869.BAL199_01149	0.0001816	53.0	COG1618@1|root,COG1618@2|Bacteria,1Q9XB@1224|Proteobacteria,2UHKY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	nucleotide phosphatase activity, acting on free nucleotides	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2728084_21	383372.Rcas_3325	4.857e-35	136.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,37506@32061|Chloroflexia	32061|Chloroflexia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GZD3_k127_2728286_1	1281779.H009_17518	1.023e-08	56.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_29,HTH_32,HTH_33
GZD3_k127_2728286_0	272568.GDI1127	1.444e-154	496.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
GZD3_k127_2762677_0	485913.Krac_0827	8.035e-56	199.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,TehB
GZD3_k127_2762677_1	1128421.JAGA01000003_gene3320	6.555e-39	157.0	COG1051@1|root,COG1051@2|Bacteria,2NQ2W@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	mutT	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_2762677_2	1200792.AKYF01000006_gene1487	4.435e-31	125.0	COG1917@1|root,COG1917@2|Bacteria,1VAF8@1239|Firmicutes,4HM4E@91061|Bacilli,270AM@186822|Paenibacillaceae	91061|Bacilli	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_2762677_3	2045.KR76_25845	7.615e-07	54.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4DN62@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2790231_0	485913.Krac_12095	8.115e-150	516.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GZD3_k127_2790231_1	1382306.JNIM01000001_gene3975	1.157e-43	171.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
GZD3_k127_2798120_3	314278.NB231_05035	2.436e-09	59.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GZD3_k127_2798120_1	485913.Krac_8271	1.08e-87	300.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
GZD3_k127_2798120_4	179408.Osc7112_3529	8.879e-05	48.0	2E3M5@1|root,32YJC@2|Bacteria,1GA02@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2798120_0	42256.RradSPS_2229	1.736e-109	359.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4CPYB@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_2798120_2	1160137.KB907307_gene1596	1.533e-09	68.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4FZG3@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
GZD3_k127_280953_2	1380387.JADM01000002_gene2059	1.13e-05	55.0	COG2050@1|root,COG2050@2|Bacteria,1RBET@1224|Proteobacteria,1SJ0P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_280953_1	1382306.JNIM01000001_gene2531	4.894e-60	220.0	COG2755@1|root,COG2755@2|Bacteria,2G7GQ@200795|Chloroflexi	200795|Chloroflexi	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD3_k127_280953_0	1128421.JAGA01000002_gene557	8.069e-124	399.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
GZD3_k127_2812141_0	485913.Krac_12006	1.263e-77	279.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_2812141_3	485913.Krac_8417	6.406e-40	151.0	COG1733@1|root,COG1733@2|Bacteria,2G792@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
GZD3_k127_2812141_2	1144275.COCOR_07590	1.95e-43	165.0	COG3554@1|root,COG3554@2|Bacteria,1PV1V@1224|Proteobacteria,42XVB@68525|delta/epsilon subdivisions,2WXJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
GZD3_k127_2812141_1	443144.GM21_0336	2.244e-72	248.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,43UUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
GZD3_k127_2822017_0	485913.Krac_6807	1.575e-121	396.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GZD3_k127_2822017_1	696747.NIES39_K03480	7.368e-50	192.0	COG4245@1|root,COG4245@2|Bacteria,1G913@1117|Cyanobacteria,1HGE2@1150|Oscillatoriales	1117|Cyanobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GZD3_k127_2822017_2	572477.Alvin_1030	0.0002788	53.0	COG0631@1|root,COG0631@2|Bacteria,1MXFV@1224|Proteobacteria,1RRJ7@1236|Gammaproteobacteria,1WWN8@135613|Chromatiales	135613|Chromatiales	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
GZD3_k127_2856387_0	1382306.JNIM01000001_gene440	2.451e-98	338.0	COG0477@1|root,COG2814@2|Bacteria,2G97R@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_2856387_1	1382306.JNIM01000001_gene514	1.011e-62	238.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
GZD3_k127_2856387_2	1229276.DI53_3741	2.354e-08	62.0	COG0745@1|root,COG0745@2|Bacteria,4NTGB@976|Bacteroidetes	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_29070_1	485913.Krac_7840	6.618e-60	218.0	COG5637@1|root,COG5637@2|Bacteria,2G9EF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
GZD3_k127_29070_0	63737.Npun_F5030	1.675e-69	240.0	COG0693@1|root,COG0693@2|Bacteria,1G526@1117|Cyanobacteria,1HQJJ@1161|Nostocales	1117|Cyanobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
GZD3_k127_2954466_3	1196028.ALEF01000043_gene524	6.548e-23	99.0	COG2132@1|root,COG2132@2|Bacteria,1V0S4@1239|Firmicutes,4HESB@91061|Bacilli	91061|Bacilli	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GZD3_k127_2954466_0	1382306.JNIM01000001_gene2394	6.36e-88	298.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_2954466_2	1382306.JNIM01000001_gene2393	2.263e-46	186.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
GZD3_k127_2954466_1	485913.Krac_4955	3.166e-65	247.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GZD3_k127_2970472_1	1382306.JNIM01000001_gene1170	8.255e-199	624.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_2970472_3	479434.Sthe_0072	2.427e-114	408.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
GZD3_k127_2970472_2	1382306.JNIM01000001_gene3905	1.943e-116	387.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GZD3_k127_2970472_7	485913.Krac_12546	4.134e-39	152.0	COG0576@1|root,COG0576@2|Bacteria	2|Bacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GZD3_k127_2970472_9	28444.JODQ01000001_gene2141	1.531e-06	56.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4EJJN@85012|Streptosporangiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
GZD3_k127_2970472_10	1303692.SFUL_5595	3.139e-05	54.0	2DQ7G@1|root,3353J@2|Bacteria,2I354@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
GZD3_k127_2970472_4	1382306.JNIM01000001_gene4140	3.721e-110	368.0	COG0240@1|root,COG0240@2|Bacteria,2G5W5@200795|Chloroflexi	200795|Chloroflexi	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
GZD3_k127_2970472_0	1380370.JIBA01000012_gene3905	1.133e-217	693.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2970472_5	266117.Rxyl_1736	9.669e-110	360.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4CPHJ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_2970472_8	326427.Cagg_0138	2.445e-13	78.0	COG0671@1|root,COG0671@2|Bacteria,2G93T@200795|Chloroflexi,377EN@32061|Chloroflexia	32061|Chloroflexia	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_2970472_6	1343740.M271_41155	6.021e-41	158.0	COG0599@1|root,COG0599@2|Bacteria,2IHPA@201174|Actinobacteria	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GZD3_k127_297794_1	68170.KL590489_gene10382	2.083e-86	291.0	COG0443@1|root,COG0443@2|Bacteria,2GP0X@201174|Actinobacteria,4E1W9@85010|Pseudonocardiales	201174|Actinobacteria	O	MreB/Mbl protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,MreB_Mbl
GZD3_k127_297794_2	575540.Isop_1018	1.848e-15	84.0	COG0576@1|root,COG0576@2|Bacteria,2J1PG@203682|Planctomycetes	203682|Planctomycetes	O	Molecular chaperone GrpE (heat shock protein)	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
GZD3_k127_297794_0	911045.PSE_0807	2.612e-134	437.0	COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,2TV8N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
GZD3_k127_297794_3	935836.JAEL01000201_gene4586	2.67e-09	57.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_302560_1	1500894.JQNN01000001_gene4294	3.265e-92	325.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,2VM6H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_302560_0	263358.VAB18032_24370	1.329e-109	374.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4D9MT@85008|Micromonosporales	201174|Actinobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_3034052_1	1380346.JNIH01000062_gene2509	4.517e-104	349.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GZD3_k127_3034052_2	1173023.KE650771_gene3869	4.994e-18	91.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_3034052_3	1173028.ANKO01000112_gene4812	3.897e-08	62.0	COG1598@1|root,COG1598@2|Bacteria,1G8YA@1117|Cyanobacteria,1HD7Z@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3034052_0	485913.Krac_2769	6.144e-108	370.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD3_k127_3038715_0	479434.Sthe_3180	2.538e-97	327.0	COG1680@1|root,COG1680@2|Bacteria,2G6QM@200795|Chloroflexi,27XFJ@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
GZD3_k127_3038715_2	1382306.JNIM01000001_gene2531	1.355e-63	230.0	COG2755@1|root,COG2755@2|Bacteria,2G7GQ@200795|Chloroflexi	200795|Chloroflexi	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD3_k127_3038715_1	485913.Krac_10080	8.112e-84	282.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GZD3_k127_3042674_2	118173.KB235914_gene651	3.859e-19	97.0	COG1357@1|root,COG1357@2|Bacteria,1G76F@1117|Cyanobacteria,1HFZR@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_3042674_0	32057.KB217483_gene9483	4.516e-77	284.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria,1HQRD@1161|Nostocales	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_3042674_1	234267.Acid_0773	1.348e-71	252.0	COG1011@1|root,COG1011@2|Bacteria,3Y4BM@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
GZD3_k127_304799_0	526227.Mesil_3052	4.29e-70	250.0	COG1070@1|root,COG1070@2|Bacteria,1WITI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.189	ko:K00854,ko:K11216	ko00040,ko01100,ko02024,map00040,map01100,map02024	M00014	R01639,R11183	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD3_k127_304799_1	1382306.JNIM01000001_gene3283	9.07e-41	159.0	2E295@1|root,32XEV@2|Bacteria	2|Bacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD3_k127_3053807_2	1121422.AUMW01000019_gene1811	1.594e-242	776.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,260C9@186807|Peptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
GZD3_k127_3053807_11	1242864.D187_009501	1.437e-34	142.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
GZD3_k127_3053807_6	326427.Cagg_3204	3.41e-91	307.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3053807_5	1382306.JNIM01000001_gene1820	1.003e-91	326.0	COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF,HATPase_c,HisKA
GZD3_k127_3053807_8	1382356.JQMP01000003_gene1960	4.623e-72	256.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,27YDQ@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_3053807_12	485913.Krac_1222	5.347e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,2G9SH@200795|Chloroflexi	485913.Krac_1222|-	T	SPTR D1CGX5 Response regulator receiver protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3053807_1	485913.Krac_1611	4.592e-250	783.0	COG2060@1|root,COG2060@2|Bacteria,2G5KK@200795|Chloroflexi	200795|Chloroflexi	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
GZD3_k127_3053807_0	485913.Krac_7322	1.117e-321	999.0	COG2216@1|root,COG2216@2|Bacteria,2G64Q@200795|Chloroflexi	200795|Chloroflexi	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
GZD3_k127_3053807_7	1382306.JNIM01000001_gene1528	5.877e-76	261.0	COG2156@1|root,COG2156@2|Bacteria,2G6R7@200795|Chloroflexi	200795|Chloroflexi	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	-	-	-	-	-	-	-	-	-	-	-	-	KdpC
GZD3_k127_3053807_3	1382306.JNIM01000001_gene1527	2.859e-135	444.0	COG0642@1|root,COG2205@2|Bacteria,2G601@200795|Chloroflexi	200795|Chloroflexi	T	Osmosensitive K+ channel His kinase sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	KdpD,Usp
GZD3_k127_3053807_13	105420.BBPO01000056_gene3451	9.103e-20	100.0	2D9QC@1|root,32TTR@2|Bacteria,2IK1S@201174|Actinobacteria,2NG5Q@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3053807_9	1382306.JNIM01000001_gene1441	8.206e-70	245.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GZD3_k127_3053807_14	1382306.JNIM01000001_gene3746	1.309e-05	53.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GZD3_k127_3053807_4	1382306.JNIM01000001_gene1978	1.426e-122	406.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
GZD3_k127_3053807_10	485913.Krac_7866	1.285e-42	163.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi	200795|Chloroflexi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_3060384_26	452863.Achl_2528	2.012e-16	87.0	2DRTH@1|root,33CZB@2|Bacteria,2GRNH@201174|Actinobacteria,1WCK1@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_27	1157490.EL26_22655	2.532e-15	88.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,27A54@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
GZD3_k127_3060384_3	1382306.JNIM01000001_gene2463	7.908e-170	556.0	COG3387@1|root,COG3387@2|Bacteria,2G7S0@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG3387 Glucoamylase and related glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GZD3_k127_3060384_13	485913.Krac_12210	9.74e-89	313.0	COG0025@1|root,COG0025@2|Bacteria,2G6RR@200795|Chloroflexi	200795|Chloroflexi	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
GZD3_k127_3060384_17	290397.Adeh_0236	6.119e-33	138.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
GZD3_k127_3060384_22	29540.C481_16847	1.364e-22	102.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GZD3_k127_3060384_16	1261545.MBE-HAL_0383	5.895e-53	195.0	arCOG07343@1|root,arCOG07343@2157|Archaea,2Y49W@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_25	765420.OSCT_2033	1.301e-16	80.0	2ASQR@1|root,31I5N@2|Bacteria,2GBA3@200795|Chloroflexi,377MY@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_8	1382306.JNIM01000001_gene3998	2.324e-101	351.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
GZD3_k127_3060384_19	485913.Krac_9157	8.753e-28	119.0	COG0511@1|root,COG0511@2|Bacteria,2G94M@200795|Chloroflexi	200795|Chloroflexi	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
GZD3_k127_3060384_2	1382306.JNIM01000001_gene105	2.716e-172	550.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GZD3_k127_3060384_1	1382306.JNIM01000001_gene106	3.866e-211	664.0	COG0439@1|root,COG0439@2|Bacteria,2G5YA@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
GZD3_k127_3060384_34	314278.NB231_12329	0.0007662	50.0	COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,1SB3H@1236|Gammaproteobacteria,1X1GY@135613|Chromatiales	135613|Chromatiales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_3060384_5	1380394.JADL01000023_gene39	4.065e-133	437.0	COG0079@1|root,COG0079@2|Bacteria,1MWPU@1224|Proteobacteria,2TRV5@28211|Alphaproteobacteria,2JVIS@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD3_k127_3060384_6	485913.Krac_7217	1.707e-126	415.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4428,PrsW-protease
GZD3_k127_3060384_21	485913.Krac_7216	1e-24	119.0	2AGQY@1|root,2ZVHH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_9	1382304.JNIL01000001_gene308	1.551e-97	331.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GZD3_k127_3060384_4	926569.ANT_19690	8.092e-151	492.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_3060384_12	1382306.JNIM01000001_gene442	1.904e-89	305.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
GZD3_k127_3060384_32	1120949.KB903294_gene3513	3.007e-07	64.0	COG4447@1|root,COG4447@2|Bacteria,2GSZJ@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_24	479434.Sthe_0094	7.99e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2G9AH@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_3060384_18	485913.Krac_2222	1.617e-31	131.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	yaeJ	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
GZD3_k127_3060384_23	1210908.HSB1_15160	2.626e-19	102.0	COG1520@1|root,arCOG02492@2157|Archaea	2157|Archaea	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
GZD3_k127_3060384_30	1370121.AUWS01000073_gene936	3.617e-10	65.0	2BGAN@1|root,32A83@2|Bacteria,2GPQS@201174|Actinobacteria,23B52@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3060384_11	485913.Krac_2038	6.876e-95	321.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD3_k127_3060384_0	1382306.JNIM01000001_gene466	2.753e-228	731.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
GZD3_k127_3060384_31	1128421.JAGA01000001_gene1995	2.348e-08	63.0	2DGRA@1|root,2ZX00@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GZD3_k127_3060384_28	390989.JOEG01000019_gene5965	3.614e-11	70.0	2DYMY@1|root,34AD9@2|Bacteria,2I408@201174|Actinobacteria,4DFMF@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
GZD3_k127_3060384_7	1382306.JNIM01000001_gene4179	1.605e-105	385.0	COG0210@1|root,COG0210@2|Bacteria,2G7JM@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,Peptidase_M78,UvrD-helicase,UvrD_C
GZD3_k127_3060384_10	1382306.JNIM01000001_gene4144	1.542e-95	331.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
GZD3_k127_3060384_15	1123288.SOV_2c09220	1.019e-67	236.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4H4H3@909932|Negativicutes	909932|Negativicutes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
GZD3_k127_3060384_14	1382306.JNIM01000001_gene2643	2.64e-80	275.0	COG1321@1|root,COG1321@2|Bacteria,2G7DY@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GZD3_k127_3068097_4	485913.Krac_12461	1.365e-35	144.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
GZD3_k127_3068097_6	485913.Krac_12241	1.752e-21	99.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
GZD3_k127_3068097_3	357808.RoseRS_2445	1.536e-47	174.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,37741@32061|Chloroflexia	32061|Chloroflexia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
GZD3_k127_3068097_2	1128421.JAGA01000002_gene1110	3.525e-90	305.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
GZD3_k127_3068097_5	1382306.JNIM01000001_gene3449	8.553e-35	140.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
GZD3_k127_3068097_0	1173021.ALWA01000020_gene235	8.626e-293	925.0	COG0466@1|root,COG0466@2|Bacteria,1G3NF@1117|Cyanobacteria	1117|Cyanobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	-	-	-	-	-	-	-	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD3_k127_3068097_1	485913.Krac_1357	1.665e-118	392.0	COG2008@1|root,COG2008@2|Bacteria	2|Bacteria	E	L-allo-threonine aldolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
GZD3_k127_3069432_7	479434.Sthe_1816	3.399e-37	148.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,27Y1J@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GZD3_k127_3069432_6	485913.Krac_8885	1.487e-39	149.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
GZD3_k127_3069432_2	1192034.CAP_6072	2.068e-122	406.0	COG0863@1|root,COG0863@2|Bacteria,1R9I2@1224|Proteobacteria,43B52@68525|delta/epsilon subdivisions,2WW0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
GZD3_k127_3069432_3	383372.Rcas_0957	1.292e-79	275.0	28I67@1|root,2Z89A@2|Bacteria,2GBVY@200795|Chloroflexi,37705@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3069432_0	1382306.JNIM01000001_gene2739	0.0	1160.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GZD3_k127_3069432_4	383372.Rcas_3573	2.9e-57	208.0	COG0526@1|root,COG0526@2|Bacteria,2G8YT@200795|Chloroflexi	200795|Chloroflexi	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
GZD3_k127_3069432_8	357808.RoseRS_1367	3.79e-21	96.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
GZD3_k127_3069432_1	485913.Krac_7368	4.947e-126	419.0	COG2271@1|root,COG2271@2|Bacteria,2G6NQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_3069432_5	1158338.JNLJ01000005_gene1771	2.202e-47	175.0	COG2107@1|root,COG2107@2|Bacteria,2G4EE@200783|Aquificae	200783|Aquificae	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GZD3_k127_3073844_3	1163408.UU9_15180	4.714e-108	361.0	COG0451@1|root,COG0451@2|Bacteria,1QHFP@1224|Proteobacteria,1SIB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GZD3_k127_3073844_2	316274.Haur_2059	9.18e-116	381.0	COG1028@1|root,COG1028@2|Bacteria,2GAK3@200795|Chloroflexi,3774Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD3_k127_3073844_4	1041146.ATZB01000040_gene362	8.675e-75	266.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,4B7XN@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
GZD3_k127_3073844_1	1128421.JAGA01000002_gene1392	9.48e-144	470.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
GZD3_k127_3073844_6	1382304.JNIL01000001_gene3105	5.105e-52	194.0	COG0580@1|root,COG0580@2|Bacteria,1UZX3@1239|Firmicutes,4HA8I@91061|Bacilli	91061|Bacilli	U	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
GZD3_k127_3073844_5	1382306.JNIM01000001_gene1969	9.202e-67	237.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	ogt	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AraC_binding,DNA_binding_1,Endonuclea_NS_2,HTH_18
GZD3_k127_3073844_7	1128421.JAGA01000002_gene1044	5.639e-39	155.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_3073844_0	324602.Caur_0341	5.634e-195	641.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,374Y5@32061|Chloroflexia	32061|Chloroflexia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
GZD3_k127_3092954_6	1382306.JNIM01000001_gene1297	2.016e-106	355.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GZD3_k127_3092954_10	1122138.AQUZ01000020_gene8257	2.258e-20	106.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4DQP9@85009|Propionibacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_3092954_8	1382306.JNIM01000001_gene1775	1.637e-43	173.0	2DCJI@1|root,2ZEEI@2|Bacteria,2G939@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3092954_0	485913.Krac_12380	1.758e-191	616.0	COG1625@1|root,COG1625@2|Bacteria,2G5XW@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
GZD3_k127_3092954_9	485913.Krac_5435	1.885e-31	126.0	COG3860@1|root,COG3860@2|Bacteria,2G9AE@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3092954_2	485913.Krac_1190	5.197e-154	498.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi	200795|Chloroflexi	F	carboxylate-amine ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
GZD3_k127_3092954_5	1382306.JNIM01000001_gene3639	9.291e-118	390.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
GZD3_k127_3092954_1	485913.Krac_2595	1.75e-190	612.0	COG0747@1|root,COG0747@2|Bacteria,2G880@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_3092954_3	485913.Krac_2594	1.616e-136	447.0	COG0601@1|root,COG0601@2|Bacteria,2G6RM@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD3_k127_3092954_4	485913.Krac_2593	1.178e-126	412.0	COG1173@1|root,COG1173@2|Bacteria,2G88M@200795|Chloroflexi	2|Bacteria	EP	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
GZD3_k127_3092954_7	1382306.JNIM01000001_gene1676	1.055e-92	312.0	COG0444@1|root,COG0444@2|Bacteria,2G6CC@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD3_k127_3097000_1	298655.KI912267_gene7025	2.242e-20	99.0	2EUDF@1|root,33MVU@2|Bacteria,2IQFI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3097000_0	1120971.AUCA01000105_gene1157	2.107e-171	546.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli	91061|Bacilli	L	For insertion sequence element IS256 in transposon Tn4001	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_3098909_0	1382306.JNIM01000001_gene3603	3.543e-286	892.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GZD3_k127_3098909_3	298654.FraEuI1c_4046	2.361e-41	175.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4ETDB@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
GZD3_k127_3098909_6	1382306.JNIM01000001_gene3507	5.569e-28	122.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
GZD3_k127_3098909_4	309801.trd_1248	6.176e-32	130.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,27YIZ@189775|Thermomicrobia	189775|Thermomicrobia	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
GZD3_k127_3098909_5	525904.Tter_0780	1.029e-28	119.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
GZD3_k127_3098909_2	1382306.JNIM01000001_gene3510	7.948e-48	189.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
GZD3_k127_3098909_1	485913.Krac_12488	5.926e-146	478.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
GZD3_k127_3102830_1	85643.Tmz1t_3374	9.77e-18	93.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD3_k127_3102830_2	525904.Tter_0346	8.104e-14	78.0	COG0762@1|root,COG0762@2|Bacteria,2NRP0@2323|unclassified Bacteria	2|Bacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
GZD3_k127_3102830_0	1120971.AUCA01000049_gene793	4.976e-47	182.0	COG4695@1|root,COG4695@2|Bacteria	2|Bacteria	N	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_Mu_F,Phage_portal
GZD3_k127_310309_2	1382306.JNIM01000001_gene2705	3.926e-88	306.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
GZD3_k127_310309_3	1382306.JNIM01000001_gene897	8.754e-77	286.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GZD3_k127_310309_4	383372.Rcas_4353	7.688e-42	156.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
GZD3_k127_310309_0	485913.Krac_7825	6.283e-237	751.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
GZD3_k127_310309_1	485913.Krac_1017	7.167e-144	458.0	COG0500@1|root,COG2226@2|Bacteria,2G81M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_310309_5	979556.MTES_3632	2.354e-14	79.0	2EGCD@1|root,33A46@2|Bacteria,2HKUV@201174|Actinobacteria,4FQBT@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
GZD3_k127_3109490_45	450851.PHZ_c1472	0.0003087	53.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2KFFV@204458|Caulobacterales	204458|Caulobacterales	P	Haloacid dehalogenase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
GZD3_k127_3109490_3	215803.DB30_6316	1.034e-171	552.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2YWVW@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GZD3_k127_3109490_32	118168.MC7420_4274	8.289e-16	91.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HCE9@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD3_k127_3109490_23	1382306.JNIM01000001_gene3283	4.213e-35	152.0	2E295@1|root,32XEV@2|Bacteria	2|Bacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD3_k127_3109490_28	420324.KI911934_gene137	1.884e-20	98.0	COG4803@1|root,COG4803@2|Bacteria,1RC5W@1224|Proteobacteria,2U8DH@28211|Alphaproteobacteria,1JR3N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_3109490_46	452637.Oter_1909	0.0003526	52.0	COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GZD3_k127_3109490_38	1132509.C447_09352	1.645e-08	60.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT7Q@28890|Euryarchaeota,23SF2@183963|Halobacteria	183963|Halobacteria	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_3109490_6	1382306.JNIM01000001_gene906	2.311e-93	323.0	COG1472@1|root,COG1472@2|Bacteria,2G8JU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
GZD3_k127_3109490_9	1382306.JNIM01000001_gene4104	3.104e-81	290.0	COG1472@1|root,COG1472@2|Bacteria	1382306.JNIM01000001_gene4104|-	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_33	1123288.SOV_1c12320	5.976e-13	77.0	COG4803@1|root,COG4803@2|Bacteria,1UJ40@1239|Firmicutes,4H4H6@909932|Negativicutes	909932|Negativicutes	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	YflT
GZD3_k127_3109490_12	479434.Sthe_1882	3.475e-71	254.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_7	1382306.JNIM01000001_gene4104	5.609e-93	321.0	COG1472@1|root,COG1472@2|Bacteria	1382306.JNIM01000001_gene4104|-	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_44	1382306.JNIM01000001_gene2933	0.0002146	48.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
GZD3_k127_3109490_19	1382306.JNIM01000001_gene98	8.533e-46	174.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
GZD3_k127_3109490_15	1114856.C496_04038	2.773e-55	204.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
GZD3_k127_3109490_18	1183438.GKIL_2106	1.613e-49	195.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
GZD3_k127_3109490_17	1183438.GKIL_2106	9.331e-50	194.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
GZD3_k127_3109490_26	696747.NIES39_Q02750	2.861e-28	125.0	COG1357@1|root,COG1357@2|Bacteria,1G62P@1117|Cyanobacteria,1HBBF@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_3109490_21	639030.JHVA01000001_gene3028	3.561e-39	149.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria,2JK5H@204432|Acidobacteriia	204432|Acidobacteriia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
GZD3_k127_3109490_8	1382306.JNIM01000001_gene2394	2.251e-91	308.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_3109490_42	525904.Tter_2546	4.45e-06	56.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_3109490_25	479434.Sthe_1843	1.433e-28	120.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_3109490_43	521674.Plim_3113	8.485e-06	55.0	COG4747@1|root,COG4747@2|Bacteria,2J4QK@203682|Planctomycetes	203682|Planctomycetes	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_31	479431.Namu_2456	5.669e-16	83.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
GZD3_k127_3109490_5	1158292.JPOE01000002_gene1710	4.051e-102	342.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2VJ4B@28216|Betaproteobacteria,1KPDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.19,2.3.1.8	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921,R01174	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
GZD3_k127_3109490_10	479434.Sthe_0314	4.426e-80	280.0	COG3285@1|root,COG3285@2|Bacteria,2GBDW@200795|Chloroflexi,27Z1A@189775|Thermomicrobia	189775|Thermomicrobia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
GZD3_k127_3109490_22	309801.trd_1809	2.651e-37	153.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_3109490_0	1123392.AQWL01000007_gene877	4.837e-256	816.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KRGE@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation transporter/ATPase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD3_k127_3109490_41	290397.Adeh_0833	1.913e-06	57.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_3109490_4	1382306.JNIM01000001_gene2397	1.152e-112	387.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GZD3_k127_3109490_2	272134.KB731326_gene299	1.129e-195	627.0	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,1H92B@1150|Oscillatoriales	1117|Cyanobacteria	S	Unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GZD3_k127_3109490_13	1463885.KL578354_gene8803	3.194e-66	233.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GZD3_k127_3109490_30	693661.Arcve_1075	3.57e-17	86.0	arCOG03230@1|root,arCOG03230@2157|Archaea	2157|Archaea	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
GZD3_k127_3109490_16	1382306.JNIM01000001_gene3283	2.469e-50	186.0	2E295@1|root,32XEV@2|Bacteria	2|Bacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
GZD3_k127_3109490_24	411463.EUBVEN_01132	5.141e-35	146.0	COG0726@1|root,COG0726@2|Bacteria,1UZGG@1239|Firmicutes,249C9@186801|Clostridia,25W7V@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
GZD3_k127_3109490_1	479434.Sthe_0757	1.863e-200	638.0	COG0654@1|root,COG0654@2|Bacteria,2G6UH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GZD3_k127_3109490_11	479434.Sthe_0758	1.52e-74	259.0	2AQF4@1|root,31FMM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_20	871963.Desdi_0742	2.131e-40	160.0	29HWC@1|root,304TF@2|Bacteria,1VJR2@1239|Firmicutes,24S15@186801|Clostridia,2658U@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
GZD3_k127_3109490_29	2074.JNYD01000016_gene4234	2.729e-18	90.0	2A6ZD@1|root,30VUF@2|Bacteria,2HA63@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_35	1101188.KI912155_gene1268	1.03e-10	72.0	2AFVV@1|root,33H4H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3109490_36	930171.Asphe3_23900	1.919e-09	63.0	arCOG08955@1|root,2ZN6H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_311256_9	365046.Rta_22275	0.0006819	50.0	COG1598@1|root,COG4226@1|root,COG1598@2|Bacteria,COG4226@2|Bacteria,1N9I2@1224|Proteobacteria	1224|Proteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB,HicB_lk_antitox
GZD3_k127_311256_0	485913.Krac_7543	7.901e-142	456.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
GZD3_k127_311256_1	485913.Krac_7544	1.264e-114	379.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
GZD3_k127_311256_3	1382306.JNIM01000001_gene3581	3.491e-77	266.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
GZD3_k127_311256_4	1382306.JNIM01000001_gene2478	5.683e-75	285.0	COG0515@1|root,COG0683@1|root,COG0515@2|Bacteria,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,Pkinase
GZD3_k127_311256_8	485913.Krac_7643	8.895e-35	142.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
GZD3_k127_311256_6	479434.Sthe_1434	5.713e-45	177.0	COG1994@1|root,COG1994@2|Bacteria,2G8WG@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_311256_7	29540.C481_20031	4.293e-44	166.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GZD3_k127_311256_2	266117.Rxyl_0136	8.716e-100	353.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4CQ4C@84995|Rubrobacteria	84995|Rubrobacteria	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
GZD3_k127_311256_5	309801.trd_A0912	3.362e-50	186.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	MA20_28490	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
GZD3_k127_3123323_4	649638.Trad_1325	6.203e-29	125.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	rsmD	-	2.1.1.171	ko:K08316,ko:K15257	-	-	R07234	RC00003	ko00000,ko01000,ko03009,ko03016	-	-	-	Cons_hypoth95
GZD3_k127_3123323_0	1382306.JNIM01000001_gene2499	4.007e-251	787.0	COG2936@1|root,COG2936@2|Bacteria,2G7NP@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
GZD3_k127_3123323_1	1382306.JNIM01000001_gene1234	4.821e-246	781.0	COG1222@1|root,COG1222@2|Bacteria,2G7KU@200795|Chloroflexi	200795|Chloroflexi	O	Cell division protein 48 (CDC48) N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,CDC48_N
GZD3_k127_3123323_2	525904.Tter_0571	1.088e-52	189.0	COG1553@1|root,COG1553@2|Bacteria,2NR2N@2323|unclassified Bacteria	2|Bacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039,ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
GZD3_k127_3123323_3	1173027.Mic7113_4388	1.575e-39	151.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HC2V@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GZD3_k127_3131990_1	1048834.TC41_0707	2.046e-167	537.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,278YJ@186823|Alicyclobacillaceae	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iYO844.BSU04360	Nramp
GZD3_k127_3131990_5	1382306.JNIM01000001_gene1472	2.358e-67	237.0	COG1321@1|root,COG1321@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
GZD3_k127_3131990_7	561175.KB894097_gene219	1.079e-27	122.0	COG3467@1|root,COG3467@2|Bacteria,2I5VH@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD3_k127_3131990_3	479434.Sthe_0485	6.037e-97	351.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
GZD3_k127_3131990_4	1278073.MYSTI_04556	1.52e-82	282.0	COG1028@1|root,COG1028@2|Bacteria,1PDTF@1224|Proteobacteria,42SIC@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	KR domain	-	-	1.1.1.413	ko:K22322	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
GZD3_k127_3131990_8	640081.Dsui_2348	3.491e-14	77.0	2EIKM@1|root,33CBX@2|Bacteria,1NHWG@1224|Proteobacteria,2W4IF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3131990_2	525904.Tter_2788	2.114e-140	451.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
GZD3_k127_3131990_0	1382356.JQMP01000003_gene2066	3.757e-186	592.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2G5P9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K02049,ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00188,M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17,3.A.1.17.2	-	-	AAA_assoc_C,ABC_tran
GZD3_k127_3131990_10	1521187.JPIM01000146_gene1308	6.978e-06	48.0	COG4986@1|root,COG4986@2|Bacteria,2G5UN@200795|Chloroflexi,376GN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GZD3_k127_3136451_0	1121877.JQKF01000022_gene2292	3.086e-212	671.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD3_k127_3140100_0	1192759.AKIB01000037_gene3262	2.83e-165	537.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2JZZ6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
GZD3_k127_3140100_1	640081.Dsui_1798	7.242e-86	291.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VHN6@28216|Betaproteobacteria,2KW8C@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
GZD3_k127_3140100_2	935845.JADQ01000018_gene3787	3.854e-06	55.0	COG0726@1|root,COG3693@1|root,COG4677@1|root,COG0726@2|Bacteria,COG3693@2|Bacteria,COG4677@2|Bacteria,1UHTC@1239|Firmicutes,4HCFD@91061|Bacilli,27498@186822|Paenibacillaceae	91061|Bacilli	G	Beta-xylanase	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0016052,GO:0016787,GO:0016798,GO:0030312,GO:0031176,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:0071944,GO:0097599,GO:1901575	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_4_9,Glyco_hydro_10,SLH
GZD3_k127_3142728_3	1382306.JNIM01000001_gene1186	2.527e-69	239.0	COG0243@1|root,COG0243@2|Bacteria,2G7V5@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
GZD3_k127_3142728_4	316274.Haur_2409	3.016e-68	243.0	COG0842@1|root,COG0842@2|Bacteria,2G7B2@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD3_k127_3142728_2	316274.Haur_2410	2.654e-114	386.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi,37761@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD3_k127_3142728_1	1380347.JNII01000008_gene4407	1.074e-155	535.0	COG2909@1|root,COG2909@2|Bacteria,2IBFJ@201174|Actinobacteria,4EX5E@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,Pkinase
GZD3_k127_3142728_0	1174528.JH992898_gene733	6.064e-210	676.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria,1JK9R@1189|Stigonemataceae	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
GZD3_k127_315583_7	196162.Noca_4459	1.956e-18	87.0	COG2128@1|root,COG2128@2|Bacteria,2HZX3@201174|Actinobacteria,4DUDY@85009|Propionibacteriales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_315583_6	196162.Noca_4459	3.104e-28	116.0	COG2128@1|root,COG2128@2|Bacteria,2HZX3@201174|Actinobacteria,4DUDY@85009|Propionibacteriales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_315583_4	211114.JOEF01000001_gene7187	2.981e-44	168.0	COG5553@1|root,COG5553@2|Bacteria,2I8K9@201174|Actinobacteria,4E62Z@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
GZD3_k127_315583_3	649638.Trad_0697	2.723e-100	339.0	COG0675@1|root,COG0675@2|Bacteria,1WJ2V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_315583_2	42256.RradSPS_0432	1.481e-106	353.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CQ6X@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_315583_1	525904.Tter_1474	6.231e-110	365.0	COG0667@1|root,COG0673@1|root,COG0667@2|Bacteria,COG0673@2|Bacteria,2NP86@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	strT	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,GFO_IDH_MocA
GZD3_k127_315583_5	1382306.JNIM01000001_gene3477	3.068e-31	131.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	rlpA	-	3.5.1.104	ko:K03642,ko:K03791,ko:K22278	-	-	-	-	ko00000,ko01000	-	GH19	-	3D,DPBB_1,Hydrolase_2,LysM
GZD3_k127_315583_0	1382306.JNIM01000001_gene274	2.115e-226	719.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
GZD3_k127_3157398_7	1382306.JNIM01000001_gene2451	1.561e-26	112.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi	200795|Chloroflexi	O	YHS domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
GZD3_k127_3157398_5	1173024.KI912149_gene6507	2.002e-80	281.0	COG2207@1|root,COG2207@2|Bacteria,1GBGG@1117|Cyanobacteria,1JK06@1189|Stigonemataceae	1117|Cyanobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
GZD3_k127_3157398_1	525904.Tter_2605	2.461e-130	436.0	COG1472@1|root,COG1472@2|Bacteria,2NNZB@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
GZD3_k127_3157398_6	485913.Krac_8141	1.429e-59	222.0	COG2971@1|root,COG2971@2|Bacteria,2G6Y6@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GZD3_k127_3157398_3	1382306.JNIM01000001_gene1420	6.344e-96	323.0	COG2103@1|root,COG2103@2|Bacteria,2G6DC@200795|Chloroflexi	200795|Chloroflexi	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
GZD3_k127_3157398_2	1382306.JNIM01000001_gene1421	2.727e-112	369.0	COG2188@1|root,COG2188@2|Bacteria,2G6ST@200795|Chloroflexi	200795|Chloroflexi	K	SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
GZD3_k127_3157398_0	485913.Krac_8139	4.933e-139	458.0	COG1820@1|root,COG1820@2|Bacteria,2G6HC@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
GZD3_k127_3157398_4	1128421.JAGA01000001_gene2305	5.613e-86	291.0	COG0449@1|root,COG0449@2|Bacteria,2NQMT@2323|unclassified Bacteria	2|Bacteria	M	SIS domain	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
GZD3_k127_3159800_3	1382306.JNIM01000001_gene154	1.383e-28	121.0	COG2030@1|root,COG2030@2|Bacteria,2G97V@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
GZD3_k127_3159800_2	1382306.JNIM01000001_gene3767	1.809e-57	213.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
GZD3_k127_3159800_1	1173024.KI912149_gene6319	1.28e-64	228.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX_1	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
GZD3_k127_3159800_0	1121405.dsmv_0645	1.887e-111	372.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2MHR8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
GZD3_k127_3159882_6	1249627.D779_3622	9.995e-14	81.0	COG4245@1|root,COG4245@2|Bacteria,1MVUE@1224|Proteobacteria,1RQ4Q@1236|Gammaproteobacteria,1WXIT@135613|Chromatiales	135613|Chromatiales	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
GZD3_k127_3159882_5	1382306.JNIM01000001_gene3367	3.225e-19	102.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	WD40
GZD3_k127_3159882_0	1128421.JAGA01000002_gene1230	4.825e-145	488.0	COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria	2|Bacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
GZD3_k127_3159882_2	485913.Krac_2058	5.755e-98	331.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
GZD3_k127_3159882_3	485913.Krac_6064	5.296e-24	108.0	COG0745@1|root,COG0745@2|Bacteria,2G9PF@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_3159882_1	485913.Krac_2867	2.108e-138	460.0	COG0467@1|root,COG0467@2|Bacteria,2G8TX@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Circadian clock protein KaiC central region	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
GZD3_k127_3159882_4	485913.Krac_3588	2.479e-23	108.0	COG0745@1|root,COG0745@2|Bacteria,2G9PF@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_3190695_4	1382306.JNIM01000001_gene2938	8.823e-22	96.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_3190695_1	666685.R2APBS1_3907	8.112e-51	198.0	COG0546@1|root,COG0546@2|Bacteria,1QEY0@1224|Proteobacteria,1S385@1236|Gammaproteobacteria,1X6BW@135614|Xanthomonadales	135614|Xanthomonadales	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3190695_2	1385510.N781_11560	1.689e-31	127.0	COG1671@1|root,COG1671@2|Bacteria,1VC3V@1239|Firmicutes,4HMPR@91061|Bacilli,2YAVA@289201|Pontibacillus	91061|Bacilli	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3190695_0	485913.Krac_11160	4.245e-165	540.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
GZD3_k127_3190695_3	1382306.JNIM01000001_gene705	6.17e-22	101.0	COG5267@1|root,COG5267@2|Bacteria,2G6X1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
GZD3_k127_3199792_3	485913.Krac_6742	3.222e-108	365.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
GZD3_k127_3199792_7	485913.Krac_5497	9.735e-69	244.0	COG0384@1|root,COG0384@2|Bacteria,2G8NU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
GZD3_k127_3199792_1	1382356.JQMP01000003_gene2033	1.61e-133	437.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GZD3_k127_3199792_9	390989.JOEG01000005_gene2033	1.972e-45	173.0	COG1309@1|root,COG1309@2|Bacteria,2HAGC@201174|Actinobacteria,4DFDZ@85008|Micromonosporales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	ko:K18476	-	M00668	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C,TetR_N
GZD3_k127_3199792_2	997346.HMPREF9374_0520	9.001e-130	423.0	COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,27CHN@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ykcA	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
GZD3_k127_3199792_4	485913.Krac_12386	5.892e-108	374.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
GZD3_k127_3199792_8	929712.KI912613_gene2301	1.851e-59	216.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CSI7@84995|Rubrobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_3199792_5	485913.Krac_2632	3.154e-105	353.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
GZD3_k127_3199792_6	485913.Krac_1321	1.535e-103	352.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
GZD3_k127_3199792_0	1382306.JNIM01000001_gene543	1.999e-157	505.0	COG0003@1|root,COG0003@2|Bacteria,2G64V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
GZD3_k127_3199792_10	1097668.BYI23_C011350	1.139e-09	68.0	COG2267@1|root,COG2267@2|Bacteria,1R9YW@1224|Proteobacteria,2VQEP@28216|Betaproteobacteria,1K0IF@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD3_k127_3200312_1	349521.HCH_06379	2.113e-64	248.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,1T43Q@1236|Gammaproteobacteria,1XQBU@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3200312_0	485913.Krac_8721	1.636e-121	406.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
GZD3_k127_3200312_2	479434.Sthe_0649	1.061e-14	77.0	COG0789@1|root,COG0789@2|Bacteria,2G9H2@200795|Chloroflexi,27Z9B@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GZD3_k127_3206312_3	383372.Rcas_1701	8.069e-56	208.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi,3780Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_3206312_0	543913.D521_1283	1.322e-76	284.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1PG72@1224|Proteobacteria,2WAVX@28216|Betaproteobacteria,1KR2F@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
GZD3_k127_3206312_1	373994.Riv7116_5783	1.362e-69	250.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,1HIGZ@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_3206312_2	426114.THI_3131	1.048e-59	219.0	COG3511@1|root,COG3511@2|Bacteria,1R78F@1224|Proteobacteria,2VXFB@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
GZD3_k127_3208184_4	373903.Hore_06870	7.445e-19	94.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,3WC2X@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
GZD3_k127_3208184_5	316274.Haur_3221	1.377e-09	71.0	COG3595@1|root,COG3595@2|Bacteria,2G7DM@200795|Chloroflexi,375KV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GZD3_k127_3208184_1	1444309.JAQG01000073_gene251	1.533e-98	345.0	COG4552@1|root,COG4552@2|Bacteria,1U5C4@1239|Firmicutes,4HF2I@91061|Bacilli	91061|Bacilli	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
GZD3_k127_3208184_3	485913.Krac_2051	2.066e-72	260.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi	200795|Chloroflexi	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
GZD3_k127_3208184_2	1382306.JNIM01000001_gene3064	6.083e-92	317.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi	200795|Chloroflexi	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
GZD3_k127_3208184_0	485913.Krac_11739	5.794e-216	691.0	COG0515@1|root,COG1199@1|root,COG0515@2|Bacteria,COG1199@2|Bacteria,2G88S@200795|Chloroflexi	200795|Chloroflexi	KLT	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,Pkinase
GZD3_k127_3213805_0	1382356.JQMP01000003_gene2075	7.303e-189	616.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
GZD3_k127_3234994_2	1382306.JNIM01000001_gene2943	8.529e-13	76.0	COG1551@1|root,COG1551@2|Bacteria	2|Bacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563,ko:K13626	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02035,ko03019	-	-	-	CsrA
GZD3_k127_3234994_1	404589.Anae109_0442	3.811e-14	78.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z1KX@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_3234994_0	1382306.JNIM01000001_gene760	5.819e-111	369.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
GZD3_k127_3238723_1	471852.Tcur_1472	6.629e-120	397.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EGVJ@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD3_k127_3238723_0	1382306.JNIM01000001_gene315	1.707e-307	960.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi	200795|Chloroflexi	I	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
GZD3_k127_3238723_3	1121373.KB903654_gene1479	2.912e-06	58.0	COG1787@1|root,COG4916@1|root,COG1787@2|Bacteria,COG4916@2|Bacteria,4PPBH@976|Bacteroidetes,47X7J@768503|Cytophagia	976|Bacteroidetes	V	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GZD3_k127_3238723_2	1283283.ATXA01000010_gene4627	1.799e-23	103.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4ESA9@85013|Frankiales	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_3243544_1	485913.Krac_6031	3.47e-85	286.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_3243544_0	485913.Krac_6032	3.234e-138	450.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD3_k127_3248081_1	485913.Krac_9065	2.024e-66	232.0	COG2085@1|root,COG2085@2|Bacteria	2|Bacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
GZD3_k127_3248081_3	1187851.A33M_3396	4.26e-20	94.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
GZD3_k127_3248081_4	1116472.MGMO_107c00050	1.047e-06	59.0	2EPXS@1|root,33HIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3248081_2	351160.LRC129	2.812e-50	191.0	COG0500@1|root,arCOG01774@2157|Archaea,2Y0T6@28890|Euryarchaeota,2NBMP@224756|Methanomicrobia	224756|Methanomicrobia	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
GZD3_k127_3248081_0	485913.Krac_10431	2.754e-93	317.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	tetV	-	-	ko:K18215	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.3	-	-	MFS_1,MFS_3
GZD3_k127_3265197_0	1382306.JNIM01000001_gene1023	1.547e-221	698.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD3_k127_3265197_2	485913.Krac_5496	2.165e-89	304.0	COG1752@1|root,COG1752@2|Bacteria,2G7GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
GZD3_k127_3265197_3	1382306.JNIM01000001_gene1022	3.249e-62	220.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
GZD3_k127_3265197_1	485913.Krac_2436	1.959e-178	570.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
GZD3_k127_3265197_4	566461.SSFG_05960	9.878e-24	112.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GZD3_k127_3267120_0	485913.Krac_8502	1.485e-152	486.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GZD3_k127_3267120_1	1382306.JNIM01000001_gene202	2.102e-42	166.0	COG0712@1|root,COG0712@2|Bacteria,2G78B@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
GZD3_k127_3288720_10	113395.AXAI01000010_gene2210	5.489e-12	78.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JRR8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_3288720_1	326427.Cagg_1859	1.636e-64	236.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_3288720_2	1121440.AUMA01000011_gene2495	9.658e-60	218.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42MDK@68525|delta/epsilon subdivisions,2X5IU@28221|Deltaproteobacteria,2MGRP@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD3_k127_3288720_7	1229780.BN381_130108	2.586e-31	138.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,3UXF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_3288720_5	358220.C380_19390	1.694e-46	179.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2VPMF@28216|Betaproteobacteria,4ABNU@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_3288720_9	926569.ANT_28190	1.728e-25	120.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	Apolipoprotein,RmuC
GZD3_k127_3288720_4	485913.Krac_9331	1.407e-48	177.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GZD3_k127_3288720_6	517418.Ctha_0380	8.181e-34	153.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1FEF0@1090|Chlorobi	1090|Chlorobi	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
GZD3_k127_3288720_8	1068978.AMETH_5010	3.944e-27	131.0	COG0784@1|root,COG4928@1|root,COG0784@2|Bacteria,COG4928@2|Bacteria,2IA83@201174|Actinobacteria,4E6QF@85010|Pseudonocardiales	201174|Actinobacteria	T	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase,Response_reg
GZD3_k127_3288720_3	1382306.JNIM01000001_gene4145	2.205e-57	210.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
GZD3_k127_3288720_0	485913.Krac_10762	3.278e-113	373.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
GZD3_k127_3290038_3	1278073.MYSTI_06620	2.215e-49	180.0	COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
GZD3_k127_3290038_8	306281.AJLK01000072_gene671	9.908e-06	55.0	COG1656@1|root,COG1656@2|Bacteria,1G86A@1117|Cyanobacteria,1JMC8@1189|Stigonemataceae	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GZD3_k127_3290038_7	631362.Thi970DRAFT_02754	2.747e-14	78.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_3290038_4	1365176.N186_08145	2.342e-24	107.0	COG1669@1|root,arCOG01206@2157|Archaea	2157|Archaea	M	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GZD3_k127_3290038_2	485913.Krac_10166	4.485e-57	203.0	COG2452@1|root,COG2452@2|Bacteria,2G7MZ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
GZD3_k127_3290038_6	485913.Krac_0348	1.18e-14	81.0	COG2452@1|root,COG2452@2|Bacteria,2G7MZ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
GZD3_k127_3290038_0	765420.OSCT_2149	3.989e-145	473.0	COG0675@1|root,COG0675@2|Bacteria,2G7TJ@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM transposase, IS605 OrfB family, central region	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_3290038_1	1382306.JNIM01000001_gene2585	3.881e-125	408.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GZD3_k127_3290038_5	1122182.KB903836_gene5118	2.734e-18	97.0	COG0741@1|root,COG0741@2|Bacteria,2II77@201174|Actinobacteria,4DDH7@85008|Micromonosporales	201174|Actinobacteria	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
GZD3_k127_3339145_1	1382306.JNIM01000001_gene3903	4.531e-59	214.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
GZD3_k127_3339145_0	485913.Krac_0894	6.708e-85	287.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD3_k127_3348321_0	1382306.JNIM01000001_gene426	7.748e-88	292.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GZD3_k127_3348321_1	1183438.GKIL_4198	1.338e-41	165.0	COG1569@1|root,COG1569@2|Bacteria,1G64T@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GZD3_k127_3348321_2	99598.Cal7507_5602	4.251e-32	131.0	COG3311@1|root,COG3311@2|Bacteria,1G6I6@1117|Cyanobacteria,1HP3P@1161|Nostocales	1117|Cyanobacteria	K	TIGRFAM DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GZD3_k127_3351621_0	1382356.JQMP01000001_gene1007	6.201e-176	566.0	COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi,27Y05@189775|Thermomicrobia	189775|Thermomicrobia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
GZD3_k127_3351621_1	485913.Krac_0414	7.758e-20	90.0	COG2924@1|root,COG2924@2|Bacteria,2G6XQ@200795|Chloroflexi	200795|Chloroflexi	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
GZD3_k127_3361633_4	927677.ALVU02000001_gene4704	4.763e-07	53.0	COG1131@1|root,COG1131@2|Bacteria,1G3BQ@1117|Cyanobacteria,1H4K5@1142|Synechocystis	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD3_k127_3361633_2	326427.Cagg_1684	2.75e-43	169.0	COG1668@1|root,COG1668@2|Bacteria,2G9RA@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GZD3_k127_3361633_6	1423734.JCM14202_3536	9.66e-05	56.0	2DPVJ@1|root,333JK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
GZD3_k127_3361633_1	1382306.JNIM01000001_gene3946	3.425e-86	297.0	COG1446@1|root,COG1446@2|Bacteria,2G6AS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
GZD3_k127_3361633_0	485913.Krac_9524	8.004e-88	297.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Glycos_transf_1,Glycos_transf_2,MethyTransf_Reg,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_2
GZD3_k127_3361633_3	485913.Krac_2194	2.483e-40	152.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GZD3_k127_3361932_0	1382306.JNIM01000001_gene358	3.827e-09	59.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
GZD3_k127_3370138_5	525904.Tter_0176	1.804e-86	296.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
GZD3_k127_3370138_11	401473.BDP_2273	1.292e-05	57.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD3_k127_3370138_7	485913.Krac_10784	1.327e-72	261.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
GZD3_k127_3370138_10	195253.Syn6312_3719	3.503e-36	149.0	COG3878@1|root,COG3878@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
GZD3_k127_3370138_0	1382306.JNIM01000001_gene2651	4.04e-185	598.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD3_k127_3370138_4	1382306.JNIM01000001_gene2650	1.834e-116	392.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,2G6GG@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
GZD3_k127_3370138_9	1536773.R70331_08355	4.646e-65	235.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,26VD8@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_3370138_2	1382306.JNIM01000001_gene2649	9.098e-123	407.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
GZD3_k127_3370138_8	485913.Krac_10783	2.271e-70	248.0	COG3382@1|root,COG3382@2|Bacteria,2G96A@200795|Chloroflexi	200795|Chloroflexi	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
GZD3_k127_3370138_6	1382306.JNIM01000001_gene2647	8.982e-83	281.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi	200795|Chloroflexi	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
GZD3_k127_3370138_1	1382306.JNIM01000001_gene2646	1.34e-159	520.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
GZD3_k127_3370138_3	1382306.JNIM01000001_gene2645	2.233e-120	398.0	COG0180@1|root,COG0180@2|Bacteria,2G5SH@200795|Chloroflexi	200795|Chloroflexi	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
GZD3_k127_3370138_12	485913.Krac_0786	3.383e-05	49.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_3381782_6	935948.KE386495_gene1997	7.233e-08	58.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F9E@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
GZD3_k127_3381782_7	797299.HALLA_03150	0.0002596	53.0	COG0392@1|root,arCOG00899@2157|Archaea,2XUZK@28890|Euryarchaeota,23UVC@183963|Halobacteria	183963|Halobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
GZD3_k127_3381782_0	1382306.JNIM01000001_gene1111	5.297e-85	303.0	COG4585@1|root,COG4585@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_3381782_1	1382306.JNIM01000001_gene1112	1.185e-78	271.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_3381782_5	485913.Krac_5148	1.584e-47	192.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
GZD3_k127_3381782_3	309801.trd_1313	1.156e-61	232.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GZD3_k127_3381782_4	1003195.SCAT_4310	9.02e-59	224.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
GZD3_k127_3381782_2	1128421.JAGA01000002_gene1221	1.284e-78	267.0	COG0277@1|root,COG0277@2|Bacteria,2NP2P@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
GZD3_k127_3396548_0	485913.Krac_8057	1.175e-135	440.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_3396548_1	485913.Krac_8058	5.389e-106	360.0	COG1215@1|root,COG1215@2|Bacteria,2G8FQ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
GZD3_k127_3396548_2	1408254.T458_04935	1.101e-63	227.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4ITCR@91061|Bacilli,277C9@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
GZD3_k127_3400073_1	926569.ANT_26080	5.502e-28	124.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_3400073_0	926569.ANT_06500	5.735e-93	309.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GZD3_k127_3424055_0	313606.M23134_00645	2.139e-114	396.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
GZD3_k127_3437299_5	864073.HFRIS_021401	9.002e-73	258.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2VNTG@28216|Betaproteobacteria,478MY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Ndr family	catD2	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
GZD3_k127_3437299_0	479434.Sthe_0607	5.179e-153	496.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
GZD3_k127_3437299_4	479434.Sthe_0604	1.073e-75	265.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
GZD3_k127_3437299_1	479434.Sthe_0603	3.062e-126	412.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
GZD3_k127_3437299_3	543728.Vapar_5436	7.952e-99	330.0	COG0702@1|root,COG0702@2|Bacteria,1MYVU@1224|Proteobacteria,2VHXZ@28216|Betaproteobacteria,4ACPH@80864|Comamonadaceae	28216|Betaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
GZD3_k127_3437299_2	675635.Psed_6455	6.892e-119	386.0	COG2267@1|root,COG2267@2|Bacteria,2HM71@201174|Actinobacteria,4EF6B@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_3437299_6	994479.GL877879_gene5375	1.531e-69	248.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4E09P@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
GZD3_k127_3437299_7	1128421.JAGA01000002_gene1704	2.378e-16	89.0	COG3301@1|root,COG3301@2|Bacteria,2NQX4@2323|unclassified Bacteria	2|Bacteria	P	Polysulfide reductase	nrfD	-	-	-	-	-	-	-	-	-	-	-	NrfD
GZD3_k127_3452297_1	709986.Deima_2417	2.253e-25	109.0	COG0796@1|root,COG0796@2|Bacteria,1WI52@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
GZD3_k127_3452297_0	1382306.JNIM01000001_gene533	1.556e-149	480.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_3465608_1	1382306.JNIM01000001_gene2639	6.54e-36	152.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GZD3_k127_3465608_5	87626.PTD2_21312	9.724e-17	90.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,2Q36Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
GZD3_k127_3465608_2	1283283.ATXA01000008_gene3187	1.226e-31	130.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria,4ET5T@85013|Frankiales	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3465608_0	67356.KL575592_gene2514	1.03e-148	485.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
GZD3_k127_3491141_3	1382306.JNIM01000001_gene390	6.694e-63	228.0	COG2021@1|root,COG2021@2|Bacteria,2G5JD@200795|Chloroflexi	200795|Chloroflexi	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GZD3_k127_3491141_0	485913.Krac_10989	1.221e-259	817.0	COG1061@1|root,COG1061@2|Bacteria,2G861@200795|Chloroflexi	200795|Chloroflexi	L	type III restriction protein res subunit	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
GZD3_k127_3491141_2	1382306.JNIM01000001_gene1251	1.338e-68	241.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GZD3_k127_3491141_7	1408433.JHXV01000059_gene3373	3.033e-05	53.0	2BWFJ@1|root,32S66@2|Bacteria,4NSFS@976|Bacteroidetes,1I4EE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3491141_1	1128421.JAGA01000002_gene1326	2.183e-112	381.0	COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma-54 factor	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GZD3_k127_3491141_4	1382306.JNIM01000001_gene328	6.639e-43	170.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
GZD3_k127_3491141_5	926569.ANT_12060	1.181e-33	135.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GZD3_k127_3501385_0	485913.Krac_2641	3.183e-106	348.0	COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi	200795|Chloroflexi	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GZD3_k127_3528135_0	414684.RC1_0381	3.465e-183	595.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPR7@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GZD3_k127_3528135_1	177437.HRM2_28700	3.803e-131	439.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHVC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GZD3_k127_3528135_2	1382306.JNIM01000001_gene1994	8.496e-42	154.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GZD3_k127_3536166_2	1366050.N234_25865	9.146e-63	221.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2VJ7U@28216|Betaproteobacteria,1K77J@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
GZD3_k127_3536166_0	694430.Natoc_3739	9.674e-66	234.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
GZD3_k127_3536166_4	926569.ANT_04440	8.116e-18	92.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
GZD3_k127_3536166_3	1382306.JNIM01000001_gene98	5.058e-25	106.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
GZD3_k127_3536166_1	1382306.JNIM01000001_gene2482	1.538e-65	231.0	COG3662@1|root,COG3662@2|Bacteria,2G8VS@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
GZD3_k127_3538420_4	1123319.AUBE01000004_gene575	5.708e-40	161.0	2E58P@1|root,33013@2|Bacteria,2I2UP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3538420_7	522306.CAP2UW1_3179	1.763e-05	53.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,2VU5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	T	dual specificity protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
GZD3_k127_3538420_2	1121381.JNIV01000045_gene886	3.933e-76	259.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,MerR,MerR_1,Redoxin
GZD3_k127_3538420_3	485913.Krac_11273	1.91e-66	244.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
GZD3_k127_3538420_0	1382306.JNIM01000001_gene34	1.604e-109	377.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
GZD3_k127_3538420_1	485913.Krac_8652	1.84e-100	344.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
GZD3_k127_3538420_5	1382306.JNIM01000001_gene31	2.829e-33	135.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
GZD3_k127_3561485_0	1382306.JNIM01000001_gene230	3.287e-155	499.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GZD3_k127_3561485_3	485913.Krac_8476	1.407e-23	106.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
GZD3_k127_3561485_2	479434.Sthe_2657	1.644e-41	160.0	COG3247@1|root,COG3247@2|Bacteria,2G8VA@200795|Chloroflexi	200795|Chloroflexi	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
GZD3_k127_3561485_1	479434.Sthe_0116	4.616e-83	287.0	COG2146@1|root,COG4244@1|root,COG2146@2|Bacteria,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
GZD3_k127_3563060_3	345341.KUTG_08092	2.757e-31	141.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD3_k127_3563060_4	1123278.KB893393_gene5614	1.19e-19	104.0	2DSQ7@1|root,33H10@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3563060_1	485913.Krac_2049	1.161e-141	479.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_3563060_0	525904.Tter_0049	4.599e-251	810.0	COG0209@1|root,COG0209@2|Bacteria,2NNVF@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
GZD3_k127_3563060_2	1382306.JNIM01000001_gene2563	2.067e-56	201.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
GZD3_k127_3564688_19	264732.Moth_0999	5.019e-13	72.0	COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,25ECT@186801|Clostridia	186801|Clostridia	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_3564688_5	485913.Krac_10139	9.89e-93	318.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_3564688_11	485913.Krac_10088	8.936e-62	222.0	COG3358@1|root,COG3358@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
GZD3_k127_3564688_21	1050202.KB913024_gene1319	7.069e-09	70.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_24,GerE,NB-ARC,TPR_12
GZD3_k127_3564688_10	1173028.ANKO01000194_gene6040	7.971e-62	244.0	COG3903@1|root,COG3903@2|Bacteria,1G5J8@1117|Cyanobacteria,1HAQI@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NB-ARC
GZD3_k127_3564688_7	479434.Sthe_2671	5.185e-88	302.0	COG1131@1|root,COG1131@2|Bacteria,2G7V6@200795|Chloroflexi,27Y6R@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_3564688_6	255470.cbdbA774	8.765e-89	309.0	COG0842@1|root,COG0842@2|Bacteria,2G6II@200795|Chloroflexi,34D9V@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
GZD3_k127_3564688_16	485913.Krac_5185	4.457e-21	93.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	attM	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
GZD3_k127_3564688_22	1463903.JOIZ01000019_gene6611	4.908e-07	63.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
GZD3_k127_3564688_13	485913.Krac_12017	8.642e-36	146.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_3564688_2	1382306.JNIM01000001_gene4224	5.009e-177	571.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
GZD3_k127_3564688_9	485913.Krac_2860	6.777e-75	264.0	COG2267@1|root,COG2267@2|Bacteria,2G6QC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD3_k127_3564688_8	1123073.KB899243_gene844	8.349e-85	302.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
GZD3_k127_3564688_18	485913.Krac_4641	2.102e-17	94.0	COG3595@1|root,COG3595@2|Bacteria,2G9KA@200795|Chloroflexi	200795|Chloroflexi	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
GZD3_k127_3564688_4	1283299.AUKG01000001_gene1825	3.644e-122	409.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
GZD3_k127_3564688_17	749414.SBI_05882	1.017e-18	99.0	29342@1|root,2ZQM6@2|Bacteria,2I8PQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3564688_0	1382306.JNIM01000001_gene3636	2.225e-187	605.0	COG1520@1|root,COG2730@1|root,COG1520@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179,ko:K20628	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase,Glyco_hydro_48,PQQ_2,Pollen_allerg_1,SLH
GZD3_k127_3564688_1	485913.Krac_8794	4.53e-182	581.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
GZD3_k127_3564688_14	485913.Krac_12070	2.985e-32	132.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
GZD3_k127_3564688_3	1120950.KB892764_gene5629	1.05e-144	471.0	COG2730@1|root,COG2730@2|Bacteria,2I2VY@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase family 5	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase
GZD3_k127_3564688_12	1382306.JNIM01000001_gene2924	2.23e-42	163.0	COG0642@1|root,COG2205@2|Bacteria	1382306.JNIM01000001_gene2924|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3568949_1	926550.CLDAP_30400	1.693e-33	143.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
GZD3_k127_3568949_0	1382306.JNIM01000001_gene1312	2.875e-109	381.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
GZD3_k127_3571764_0	485913.Krac_12597	4.464e-102	342.0	COG0477@1|root,COG2814@2|Bacteria,2G5SP@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD3_k127_3571764_1	1382306.JNIM01000001_gene4110	7.499e-86	293.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GZD3_k127_3572159_2	1122611.KB903943_gene1520	1.225e-15	82.0	COG2186@1|root,COG2186@2|Bacteria,2IB40@201174|Actinobacteria,4EM5I@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GZD3_k127_3572159_0	234267.Acid_2681	1.333e-154	499.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
GZD3_k127_3572159_1	657309.BXY_46610	5.865e-26	110.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,2FPMF@200643|Bacteroidia,4AKQ0@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
GZD3_k127_3577916_7	485913.Krac_12365	2.327e-74	263.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
GZD3_k127_3577916_4	485913.Krac_12366	1.231e-91	309.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
GZD3_k127_3577916_8	1278308.KB907080_gene2362	6.338e-69	256.0	COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria,4FRR1@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_3577916_6	518766.Rmar_2434	4.187e-79	287.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	luxQ1	-	2.1.1.80,2.7.13.3,2.7.8.41,3.1.1.61,3.1.3.3	ko:K07315,ko:K07716,ko:K08744,ko:K13924	ko00564,ko01100,ko02020,ko02030,ko04112,map00564,map01100,map02020,map02030,map04112	M00506,M00511	R02030	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
GZD3_k127_3577916_1	479434.Sthe_0181	5.33e-101	344.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,27YXC@189775|Thermomicrobia	189775|Thermomicrobia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_3577916_2	479434.Sthe_0182	1.146e-96	325.0	COG0745@1|root,COG0745@2|Bacteria,2G88F@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_3577916_11	179408.Osc7112_3529	0.0006441	47.0	2E3M5@1|root,32YJC@2|Bacteria,1GA02@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3577916_3	485913.Krac_11868	2.024e-96	352.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_3577916_0	1382306.JNIM01000001_gene1523	2.674e-111	375.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
GZD3_k127_3577916_5	485913.Krac_11870	2.156e-80	274.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_3577916_9	1382306.JNIM01000001_gene3645	3.213e-25	106.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GZD3_k127_3593997_1	485913.Krac_0836	1.225e-40	152.0	COG0473@1|root,COG0473@2|Bacteria,2G8A7@200795|Chloroflexi	200795|Chloroflexi	C	Tartrate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
GZD3_k127_3593997_3	268407.PWYN_12730	4.546e-11	74.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
GZD3_k127_3593997_2	1111454.HMPREF1250_1491	6.563e-25	114.0	2CIU6@1|root,32S8H@2|Bacteria,1VBBK@1239|Firmicutes,4H5TU@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3593997_0	1479237.JMLY01000001_gene3126	1.368e-50	192.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,4670X@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	enoyl-CoA hydratase	atuE	-	4.2.1.57	ko:K13779	ko00281,map00281	-	R03493	RC00941	ko00000,ko00001,ko01000	-	-	-	ECH_1
GZD3_k127_3599499_0	485913.Krac_7672	3.248e-276	867.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi	200795|Chloroflexi	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
GZD3_k127_3599499_1	1382306.JNIM01000001_gene999	3.272e-131	436.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GZD3_k127_3599499_4	1121924.ATWH01000001_gene4463	7.298e-37	151.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
GZD3_k127_3599499_2	399549.Msed_1206	2.703e-56	215.0	COG3794@1|root,arCOG02917@2157|Archaea,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	pcy	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
GZD3_k127_3599499_3	485913.Krac_6991	6.819e-56	211.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD3_k127_3612320_0	1227497.C491_02036	2.242e-20	99.0	COG3685@1|root,arCOG11147@2157|Archaea,2XUVS@28890|Euryarchaeota,23UYB@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
GZD3_k127_36142_0	1265505.ATUG01000001_gene3026	5.879e-111	377.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
GZD3_k127_361737_0	479434.Sthe_1900	1.553e-131	429.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi,27XG3@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
GZD3_k127_3629079_1	1183438.GKIL_2981	3.564e-171	548.0	COG0001@1|root,COG0001@2|Bacteria,1G162@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD3_k127_3629079_4	485913.Krac_10581	1.99e-102	348.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
GZD3_k127_3629079_19	525379.HMPREF0819_1357	3.369e-05	56.0	28MIG@1|root,2ZAV8@2|Bacteria,1V2VJ@1239|Firmicutes,4HHCS@91061|Bacilli	91061|Bacilli	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
GZD3_k127_3629079_10	765420.OSCT_1817	8.006e-57	210.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi,377UC@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GZD3_k127_3629079_11	485913.Krac_1090	4.974e-55	199.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
GZD3_k127_3629079_15	997346.HMPREF9374_0620	5.924e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,1TU1P@1239|Firmicutes,4INN7@91061|Bacilli,27D5B@186824|Thermoactinomycetaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3629079_3	981369.JQMJ01000004_gene4605	4.279e-129	422.0	COG3391@1|root,COG3391@2|Bacteria,2GP3N@201174|Actinobacteria,2NF58@228398|Streptacidiphilus	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3629079_6	485913.Krac_5786	7.456e-82	294.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_3629079_12	1382306.JNIM01000001_gene2787	6.881e-43	166.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
GZD3_k127_3629079_16	568816.Acin_1316	5.193e-15	87.0	28NXW@1|root,2ZBV8@2|Bacteria,1V1D2@1239|Firmicutes	1239|Firmicutes	L	SacI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_SacI
GZD3_k127_3629079_2	1041930.Mtc_2241	1.704e-129	421.0	COG0338@1|root,arCOG03416@2157|Archaea,2XWJX@28890|Euryarchaeota	28890|Euryarchaeota	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
GZD3_k127_3629079_17	526227.Mesil_3470	3.556e-14	78.0	COG2329@1|root,COG2329@2|Bacteria,1WNAU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
GZD3_k127_3629079_9	1121924.ATWH01000010_gene1007	3.422e-61	222.0	COG1309@1|root,COG1309@2|Bacteria,2I8Z7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_3629079_0	1380390.JIAT01000013_gene123	5.669e-319	990.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
GZD3_k127_3629079_5	1173027.Mic7113_0499	1.402e-84	284.0	COG5588@1|root,COG5588@2|Bacteria,1GGUP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
GZD3_k127_3629079_7	1173027.Mic7113_0498	6.804e-70	247.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
GZD3_k127_3629079_13	1173024.KI912149_gene5559	1.36e-30	128.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1JM95@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GZD3_k127_3629079_18	1121937.AUHJ01000015_gene93	5.49e-09	62.0	2EKEB@1|root,33E4I@2|Bacteria,1NI9U@1224|Proteobacteria,1SGHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3629079_8	485913.Krac_5159	8.411e-63	229.0	COG3173@1|root,COG3173@2|Bacteria,2G8QR@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_3638229_1	717606.PaecuDRAFT_2765	4.389e-101	334.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	lcfA	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD3_k127_3638229_0	1382306.JNIM01000001_gene312	9.819e-216	685.0	COG1960@1|root,COG1960@2|Bacteria,2G7UB@200795|Chloroflexi	200795|Chloroflexi	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_3638229_2	709986.Deima_2134	3.58e-13	78.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,DUF4442
GZD3_k127_364166_1	37919.EP51_00200	8.42e-26	118.0	COG1309@1|root,COG1309@2|Bacteria,2IFH9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_364166_2	1530186.JQEY01000005_gene3654	8.131e-05	55.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	geranylgeranyl reductase	bchP	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2
GZD3_k127_364166_0	485913.Krac_12089	1.512e-47	176.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GZD3_k127_3645832_1	1267533.KB906734_gene4083	2.243e-06	56.0	COG5485@1|root,COG5485@2|Bacteria,3Y7UD@57723|Acidobacteria,2JN18@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
GZD3_k127_3645832_0	1173024.KI912148_gene3044	6.184e-37	150.0	COG0454@1|root,COG0456@2|Bacteria,1GGD2@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3651789_1	1382306.JNIM01000001_gene1442	8.483e-103	349.0	COG2195@1|root,COG2195@2|Bacteria,2G7H0@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD3_k127_3651789_0	1382306.JNIM01000001_gene1805	2.273e-186	594.0	COG0031@1|root,COG0031@2|Bacteria,2G5JV@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	CBS,PALP
GZD3_k127_3651789_2	479434.Sthe_2426	1.554e-08	66.0	COG1225@1|root,COG1225@2|Bacteria,2GA29@200795|Chloroflexi,27YRA@189775|Thermomicrobia	189775|Thermomicrobia	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GZD3_k127_3661891_1	479434.Sthe_2776	2.218e-157	502.0	COG1529@1|root,COG1529@2|Bacteria,2G7QH@200795|Chloroflexi,27YUU@189775|Thermomicrobia	189775|Thermomicrobia	C	Carbon-monoxide dehydrogenase, large subunit	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD3_k127_3661891_4	479434.Sthe_2777	1.596e-79	276.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
GZD3_k127_3661891_2	309801.trd_A0566	3.893e-101	337.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD3_k127_3661891_3	929562.Emtol_0801	5.821e-100	336.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
GZD3_k127_3661891_0	357808.RoseRS_2884	8.845e-192	605.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi,376KP@32061|Chloroflexia	32061|Chloroflexia	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
GZD3_k127_3661891_5	926569.ANT_24910	3.564e-75	259.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
GZD3_k127_3683525_1	485913.Krac_2664	4.766e-16	84.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_3683525_0	1382306.JNIM01000001_gene974	2.16e-103	342.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD3_k127_368355_2	368408.Tpen_1572	7.484e-21	94.0	COG0433@1|root,arCOG00280@2157|Archaea,2XQ2W@28889|Crenarchaeota	28889|Crenarchaeota	L	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
GZD3_k127_368355_0	1382306.JNIM01000001_gene4131	1.48e-67	249.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	-	ko:K03546,ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
GZD3_k127_368355_1	1382306.JNIM01000001_gene4130	8.78e-50	198.0	COG0419@1|root,COG1122@1|root,COG0419@2|Bacteria,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K03546,ko:K16786,ko:K16787,ko:K19171	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048,ko03400	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	AAA_23,ABC_tran
GZD3_k127_3687156_1	644282.Deba_3141	8.163e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
GZD3_k127_3687156_0	485913.Krac_10601	1.625e-93	311.0	COG1164@1|root,COG1164@2|Bacteria,2G60A@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD3_k127_3737982_1	1463856.JOHY01000032_gene2957	2.56e-64	225.0	COG4409@1|root,COG4409@2|Bacteria,2GN94@201174|Actinobacteria	201174|Actinobacteria	G	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
GZD3_k127_3737982_0	326427.Cagg_2751	7.059e-86	291.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
GZD3_k127_3737982_2	1283283.ATXA01000031_gene4211	2.284e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4ET6N@85013|Frankiales	201174|Actinobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_3737982_3	926554.KI912637_gene3424	9.854e-20	94.0	COG2388@1|root,COG2388@2|Bacteria	2|Bacteria	S	GCN5-related N-acetyl-transferase	-	-	2.7.7.7	ko:K02346,ko:K06975	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Acetyltransf_CG,CMD
GZD3_k127_3737982_4	485913.Krac_1276	2.534e-12	68.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GZD3_k127_3742403_0	1121272.KB903250_gene2734	8.309e-219	690.0	COG1260@1|root,COG1260@2|Bacteria,2GJVN@201174|Actinobacteria	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
GZD3_k127_3742403_2	1382306.JNIM01000001_gene4083	4.741e-118	383.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_3742403_4	192952.MM_0529	2.829e-64	233.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUZM@28890|Euryarchaeota,2NB9P@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_3742403_5	485913.Krac_7430	3.3e-63	224.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_3742403_3	867903.ThesuDRAFT_01097	9.379e-82	284.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD3_k127_3742403_1	485913.Krac_7537	1.712e-159	511.0	COG1899@1|root,COG1899@2|Bacteria,2G9B5@200795|Chloroflexi	200795|Chloroflexi	O	Deoxyhypusine synthase	-	-	-	-	-	-	-	-	-	-	-	-	DS
GZD3_k127_3760862_2	1487953.JMKF01000069_gene116	1.002e-10	72.0	COG1280@1|root,COG1280@2|Bacteria,1G5MM@1117|Cyanobacteria,1HBTI@1150|Oscillatoriales	1117|Cyanobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
GZD3_k127_3760862_4	1096756.ATKN01000021_gene1615	0.0003627	47.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD3_k127_3760862_0	1382306.JNIM01000001_gene2759	1.162e-89	310.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Chlorophyllase2,DLH,Hydrolase_4
GZD3_k127_3760862_3	118173.KB235914_gene2632	9.04e-08	54.0	COG2066@1|root,COG2066@2|Bacteria,1G1IK@1117|Cyanobacteria,1H7V2@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the glutaminase family	-	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
GZD3_k127_3760862_1	765911.Thivi_1403	8.752e-11	65.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1WYNM@135613|Chromatiales	135613|Chromatiales	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
GZD3_k127_3792306_1	1121091.AUMP01000023_gene3848	5.919e-110	370.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli	91061|Bacilli	Q	Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GZD3_k127_3792306_0	485913.Krac_7143	4.86e-120	394.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GZD3_k127_3792306_2	525904.Tter_2164	1.083e-98	334.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
GZD3_k127_3792306_3	63737.Npun_F4016	1.045e-53	195.0	COG0698@1|root,COG0698@2|Bacteria,1G9WT@1117|Cyanobacteria,1HS96@1161|Nostocales	1117|Cyanobacteria	G	TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
GZD3_k127_3792306_5	649638.Trad_1879	1.745e-19	91.0	COG2261@1|root,COG2261@2|Bacteria,1WKV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD3_k127_3792306_6	215803.DB30_7863	2.341e-08	59.0	2DSH6@1|root,33G41@2|Bacteria,1PAG8@1224|Proteobacteria,437DQ@68525|delta/epsilon subdivisions,2X2JT@28221|Deltaproteobacteria,2Z0MY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3792306_4	1499967.BAYZ01000154_gene1510	8.225e-23	102.0	COG0162@1|root,COG0162@2|Bacteria,2NNMR@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
GZD3_k127_3793713_4	395495.Lcho_2292	1.776e-86	290.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KK5U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
GZD3_k127_3793713_5	383372.Rcas_1515	2.499e-26	112.0	COG0095@1|root,COG0095@2|Bacteria,2G9B4@200795|Chloroflexi	200795|Chloroflexi	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3793713_3	383372.Rcas_1514	4.174e-118	385.0	COG0095@1|root,COG0095@2|Bacteria,2G7JY@200795|Chloroflexi	200795|Chloroflexi	H	biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GZD3_k127_3793713_0	266117.Rxyl_2564	2.589e-188	601.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria	201174|Actinobacteria	S	MmgE PrpD family protein	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GZD3_k127_3793713_2	1382306.JNIM01000001_gene2761	7.766e-134	431.0	COG1809@1|root,COG1809@2|Bacteria	2|Bacteria	S	phosphosulfolactate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	ComA
GZD3_k127_3793713_1	1382306.JNIM01000001_gene2738	9.564e-146	473.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_3796582_2	1382306.JNIM01000001_gene1523	3.948e-113	376.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
GZD3_k127_3796582_0	485913.Krac_11868	2.477e-152	519.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_3796582_4	1382306.JNIM01000001_gene1987	1.573e-85	303.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_3796582_1	485913.Krac_6780	2.548e-120	395.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
GZD3_k127_3796582_6	342113.DM82_1758	6.982e-27	112.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
GZD3_k127_3796582_3	429009.Adeg_1912	7.997e-102	347.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,42EJY@68295|Thermoanaerobacterales	186801|Clostridia	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
GZD3_k127_3796582_5	1382306.JNIM01000001_gene241	4.68e-57	209.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	2.6.1.9	ko:K00817,ko:K11777	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	HAD_2,Hydrolase,Hydrolase_like
GZD3_k127_38001_10	278963.ATWD01000002_gene906	1.53e-28	124.0	COG3336@1|root,COG3336@2|Bacteria,3Y3CM@57723|Acidobacteria,2JKAF@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GZD3_k127_38001_17	1223521.BBJX01000008_gene1248	7.594e-08	61.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,4AA6B@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
GZD3_k127_38001_1	1380390.JIAT01000014_gene6065	9.586e-154	508.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CS3H@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
GZD3_k127_38001_9	469383.Cwoe_1903	5.849e-37	152.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
GZD3_k127_38001_13	1121877.JQKF01000024_gene2408	1.635e-14	83.0	arCOG07408@1|root,2ZWPP@2|Bacteria,2HGM2@201174|Actinobacteria,4CNJ3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_38001_15	671143.DAMO_2364	4.039e-11	73.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	prhJ	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HisKA,PAS,PAS_4,PAS_9,Response_reg
GZD3_k127_38001_5	485913.Krac_1351	5.799e-79	274.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_38001_19	570268.ANBB01000008_gene4767	0.0007624	51.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria,4EG7K@85012|Streptosporangiales	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
GZD3_k127_38001_8	485913.Krac_8071	3.26e-66	239.0	COG3509@1|root,COG3509@2|Bacteria,2G91Y@200795|Chloroflexi	200795|Chloroflexi	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
GZD3_k127_38001_18	1449976.KALB_3541	2.01e-05	56.0	COG3227@1|root,COG3979@1|root,COG3227@2|Bacteria,COG3979@2|Bacteria,2I341@201174|Actinobacteria,4DXIM@85010|Pseudonocardiales	201174|Actinobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,P_proprotein,PepSY,Peptidase_M4,Peptidase_M4_C
GZD3_k127_38001_7	485913.Krac_9652	6.267e-73	265.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_38001_14	479434.Sthe_1708	2.099e-13	81.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
GZD3_k127_38001_12	105425.BBPL01000027_gene580	8.823e-22	96.0	COG2346@1|root,COG3369@1|root,COG3592@1|root,COG2346@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,2GMG5@201174|Actinobacteria,2NI62@228398|Streptacidiphilus	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin,Fer4_19,zf-CDGSH
GZD3_k127_38001_11	309801.trd_A0155	4.004e-25	108.0	COG2197@1|root,COG3170@1|root,COG2197@2|Bacteria,COG3170@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	189775|Thermomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_38001_6	383372.Rcas_4227	1.271e-77	266.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_38001_3	485913.Krac_6032	2.625e-114	403.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
GZD3_k127_38001_2	1382306.JNIM01000001_gene1177	2.461e-139	454.0	COG1364@1|root,COG1364@2|Bacteria,2G64K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
GZD3_k127_38001_0	485913.Krac_11095	1.103e-166	533.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
GZD3_k127_38001_4	485913.Krac_11128	2.664e-105	359.0	COG0457@1|root,COG0457@2|Bacteria	485913.Krac_11128|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3813388_2	1382306.JNIM01000001_gene1224	2.335e-17	83.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
GZD3_k127_3813388_1	1382306.JNIM01000001_gene1286	7.855e-110	364.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi	200795|Chloroflexi	H	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
GZD3_k127_3813388_0	1382306.JNIM01000001_gene1287	5.717e-134	443.0	COG0771@1|root,COG0771@2|Bacteria,2GBHB@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
GZD3_k127_3814822_1	926550.CLDAP_23450	1.146e-23	106.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
GZD3_k127_3814822_0	1382306.JNIM01000001_gene3774	3.958e-154	498.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
GZD3_k127_3819630_0	1382306.JNIM01000001_gene665	3.184e-166	532.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
GZD3_k127_3819630_3	1382306.JNIM01000001_gene1269	1.503e-33	134.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene1269|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3819630_2	1382306.JNIM01000001_gene2548	8.867e-54	209.0	COG0642@1|root,COG2205@2|Bacteria,2G8UJ@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GZD3_k127_3819630_7	1136138.JH604625_gene3646	0.0004237	48.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,1SBAA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	regulator	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
GZD3_k127_3819630_5	485913.Krac_9143	3.706e-15	81.0	COG3293@1|root,COG3293@2|Bacteria,2G8FN@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GZD3_k127_3819630_6	864069.MicloDRAFT_00006450	6.569e-08	55.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,1JTPR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
GZD3_k127_3819630_1	192952.MM_2650	1.147e-115	378.0	COG0596@1|root,arCOG01648@2157|Archaea,2Y06J@28890|Euryarchaeota,2N9YM@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
GZD3_k127_3819630_4	211165.AJLN01000104_gene6616	5.176e-26	116.0	COG1357@1|root,COG1357@2|Bacteria,1G02C@1117|Cyanobacteria,1JJI1@1189|Stigonemataceae	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
GZD3_k127_3826054_1	1382306.JNIM01000001_gene243	4.336e-21	97.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GZD3_k127_3826054_2	1209072.ALBT01000009_gene3062	1.836e-16	93.0	COG2133@1|root,COG3210@1|root,COG2133@2|Bacteria,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,1FH0J@10|Cellvibrio	1236|Gammaproteobacteria	GU	pyrroloquinoline quinone binding	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3,PA14
GZD3_k127_3826054_0	401526.TcarDRAFT_0123	6.498e-29	120.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4H25E@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
GZD3_k127_3835843_0	485913.Krac_7670	3.228e-160	525.0	COG2234@1|root,COG3291@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,2G9MK@200795|Chloroflexi	200795|Chloroflexi	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
GZD3_k127_3835843_1	28042.GU90_14780	3.31e-24	111.0	2F3WI@1|root,33WNQ@2|Bacteria,2IK8X@201174|Actinobacteria,4E444@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
GZD3_k127_3847201_2	485913.Krac_11748	1.068e-53	195.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
GZD3_k127_3847201_0	756067.MicvaDRAFT_2471	3.058e-273	865.0	COG0827@1|root,COG0827@2|Bacteria,1G0Q3@1117|Cyanobacteria,1H9WB@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Restriction endonuclease, type II, BsuBI PstI, C-terminal	-	GO:0000737,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006304,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009036,GO:0009056,GO:0009057,GO:0009307,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044355,GO:0046483,GO:0046700,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1901361,GO:1901575	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	BsuBI_PstI_RE,Eco57I
GZD3_k127_3847201_1	485913.Krac_8763	2.858e-166	539.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_3852970_2	1382306.JNIM01000001_gene3478	3.15e-68	235.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
GZD3_k127_3852970_5	1337936.IJ00_01840	1.551e-09	65.0	COG2442@1|root,COG2442@2|Bacteria,1GJIZ@1117|Cyanobacteria,1HSRY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_3852970_4	118166.JH976537_gene2659	1.129e-09	63.0	COG4634@1|root,COG4634@2|Bacteria,1G7FS@1117|Cyanobacteria,1HBRJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3852970_6	102232.GLO73106DRAFT_00002920	0.000842	46.0	COG4634@1|root,COG4634@2|Bacteria,1G720@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3852970_1	1128421.JAGA01000003_gene2827	5.315e-77	265.0	COG1926@1|root,COG1926@2|Bacteria,2NQVQ@2323|unclassified Bacteria	2|Bacteria	S	Phosphoribosyl transferase domain	minD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
GZD3_k127_3852970_0	483219.LILAB_29380	3.722e-90	312.0	COG2823@1|root,COG5637@1|root,COG2823@2|Bacteria,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,437A8@68525|delta/epsilon subdivisions,2X2EK@28221|Deltaproteobacteria,2YVIY@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
GZD3_k127_3852970_3	106370.Francci3_3987	3.078e-13	74.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4ES6H@85013|Frankiales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
GZD3_k127_3860526_3	485913.Krac_9379	3.317e-54	195.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_3860526_0	485913.Krac_8072	1.634e-284	915.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
GZD3_k127_3860526_1	1121033.AUCF01000032_gene2651	4.682e-115	386.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JPPM@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_3860526_4	269799.Gmet_2306	3.362e-09	70.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
GZD3_k127_3860526_2	479434.Sthe_2134	1.557e-66	239.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
GZD3_k127_3866853_4	1410668.JNKC01000007_gene800	2.04e-36	153.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EAC@31979|Clostridiaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD3_k127_3866853_2	485913.Krac_1087	1.529e-58	211.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD3_k127_3866853_3	981369.JQMJ01000003_gene7346	9.115e-48	192.0	COG0515@1|root,COG0515@2|Bacteria,2GM1F@201174|Actinobacteria,2NGUM@228398|Streptacidiphilus	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD3_k127_3866853_1	292459.STH2662	8.182e-67	241.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap,Peptidase_M15
GZD3_k127_3866853_0	1382306.JNIM01000001_gene856	8.628e-167	544.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
GZD3_k127_3867975_0	446470.Snas_0537	2.866e-300	962.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
GZD3_k127_3867975_1	383372.Rcas_4327	3.578e-116	397.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GZD3_k127_3873339_0	1382306.JNIM01000001_gene2519	8.418e-137	443.0	COG1015@1|root,COG1015@2|Bacteria,2G7S7@200795|Chloroflexi	200795|Chloroflexi	F	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
GZD3_k127_3873339_3	1382306.JNIM01000001_gene3991	2.684e-87	313.0	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	celA	-	3.2.1.11,3.2.1.4,3.2.1.94	ko:K01179,ko:K05988,ko:K20847	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308,R11309	-	ko00000,ko00001,ko01000	-	GH27,GH5,GH66,GH9	-	CBM_17_28,CBM_2,Cellulase,SLH
GZD3_k127_3873339_8	1196322.A370_04095	7.568e-26	121.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,24A44@186801|Clostridia,36HFC@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
GZD3_k127_3873339_13	768671.ThimaDRAFT_1313	3.885e-10	64.0	COG1487@1|root,COG1487@2|Bacteria,1RHQJ@1224|Proteobacteria,1TKC4@1236|Gammaproteobacteria,1X1S9@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_3873339_9	485913.Krac_8808	1.391e-16	80.0	COG0230@1|root,COG0230@2|Bacteria,2G7BX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
GZD3_k127_3873339_11	1121017.AUFG01000029_gene454	5.965e-15	81.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4FHJI@85021|Intrasporangiaceae	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
GZD3_k127_3873339_7	1382306.JNIM01000001_gene4049	3.118e-33	129.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
GZD3_k127_3873339_6	485913.Krac_8805	1.435e-52	205.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
GZD3_k127_3873339_4	485913.Krac_8804	3.923e-66	235.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
GZD3_k127_3873339_12	1299327.I546_5990	8.197e-14	86.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,2330W@1762|Mycobacteriaceae	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
GZD3_k127_3873339_2	485913.Krac_10268	9.473e-96	325.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
GZD3_k127_3873339_1	1382306.JNIM01000001_gene1626	9.185e-97	338.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
GZD3_k127_3873339_14	935836.JAEL01000201_gene4586	2.227e-07	61.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3877465_7	485913.Krac_3455	2.03e-87	294.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
GZD3_k127_3877465_10	1195236.CTER_0109	1.726e-46	169.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,24JIQ@186801|Clostridia	186801|Clostridia	G	PFAM Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_3877465_16	522306.CAP2UW1_4415	9.747e-05	47.0	COG2442@1|root,COG2442@2|Bacteria,1NH1S@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_3877465_0	395495.Lcho_2118	5.725e-187	599.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,1KJ65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	accB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD3_k127_3877465_9	1382306.JNIM01000001_gene678	1.508e-48	186.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
GZD3_k127_3877465_8	1521187.JPIM01000029_gene1574	3.855e-67	249.0	COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD3_k127_3877465_6	1382306.JNIM01000001_gene1275	3.082e-94	330.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_3877465_1	1382306.JNIM01000001_gene1072	1.168e-186	599.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
GZD3_k127_3877465_3	1382306.JNIM01000001_gene1073	3.78e-127	417.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GZD3_k127_3877465_2	485913.Krac_10598	1.75e-127	415.0	COG1398@1|root,COG1398@2|Bacteria,2G88P@200795|Chloroflexi	200795|Chloroflexi	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
GZD3_k127_3877465_12	330214.NIDE3327	3.066e-25	111.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
GZD3_k127_3877465_13	1173023.KE650771_gene2390	7.727e-20	91.0	COG1724@1|root,COG1724@2|Bacteria,1G7S1@1117|Cyanobacteria,1JMP3@1189|Stigonemataceae	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_3877465_14	706587.Desti_5213	1.256e-15	83.0	COG1598@1|root,COG1598@2|Bacteria,1NDHG@1224|Proteobacteria,432RS@68525|delta/epsilon subdivisions,2WXV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3877465_11	272123.Anacy_2526	2.21e-26	114.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria,1HU1X@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3877465_4	1125863.JAFN01000001_gene2408	9.158e-101	350.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
GZD3_k127_3877465_5	485913.Krac_9054	4.848e-98	329.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
GZD3_k127_3896677_2	1463879.JOHP01000074_gene3730	2.815e-16	87.0	COG0265@1|root,COG0265@2|Bacteria,2GK4U@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin_2
GZD3_k127_3896677_1	264732.Moth_1477	2.605e-34	151.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,42HW1@68295|Thermoanaerobacterales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_3896677_0	1123065.ATWL01000032_gene3391	9.461e-49	188.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_3897103_0	485913.Krac_12092	7.882e-241	759.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD3_k127_3897103_5	485913.Krac_12093	4.896e-47	175.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
GZD3_k127_3897103_8	388467.A19Y_0305	2.018e-07	53.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria,1HCDB@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
GZD3_k127_3897103_3	485913.Krac_3309	3.301e-63	223.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc,Polyketide_cyc2
GZD3_k127_3897103_9	204669.Acid345_0197	1.128e-05	58.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3897103_1	485913.Krac_5322	1.951e-78	268.0	COG2320@1|root,COG2320@2|Bacteria	2|Bacteria	Q	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	-	-	-	-	-	-	-	-	-	-	GrpB,Methyltransf_11
GZD3_k127_3897103_2	1382306.JNIM01000001_gene81	1.283e-67	243.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
GZD3_k127_3897103_6	1382306.JNIM01000001_gene4065	2.946e-28	116.0	COG2128@1|root,COG2128@2|Bacteria,2G8VF@200795|Chloroflexi	200795|Chloroflexi	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3897124_0	485913.Krac_7644	3.74e-137	448.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
GZD3_k127_3897124_1	1382306.JNIM01000001_gene145	1.871e-134	462.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
GZD3_k127_3897124_7	1382356.JQMP01000003_gene2515	1.459e-08	62.0	2A4SM@1|root,30TE1@2|Bacteria,2GA2B@200795|Chloroflexi,27YRH@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3897124_4	1382306.JNIM01000001_gene1397	1.021e-68	237.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
GZD3_k127_3897124_5	1244869.H261_01387	2.645e-40	155.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2JTRD@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
GZD3_k127_3897124_2	1382306.JNIM01000001_gene291	1.054e-96	332.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GZD3_k127_3897124_6	1382306.JNIM01000001_gene3627	1.35e-24	110.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene3627|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3897124_8	1419583.V466_10225	8.84e-05	52.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1YRH5@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	Two component signalling adaptor domain	wspB	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
GZD3_k127_3897124_3	575540.Isop_3690	8.044e-84	312.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,2IWWG@203682|Planctomycetes	203682|Planctomycetes	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
GZD3_k127_3898461_0	1386089.N865_20090	1.156e-245	769.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4FFC5@85021|Intrasporangiaceae	201174|Actinobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_3898461_1	111780.Sta7437_0491	3.468e-137	494.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3VNFS@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
GZD3_k127_3898461_2	1173027.Mic7113_4836	1.622e-43	186.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1GHCI@1117|Cyanobacteria,1H8J3@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA_2,PAS_3,PAS_4,PAS_9
GZD3_k127_3905252_2	926560.KE387023_gene1223	2.604e-56	200.0	COG1397@1|root,COG1397@2|Bacteria,1WN8X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GZD3_k127_3905252_3	880072.Desac_0263	2.161e-41	175.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GZD3_k127_3905252_0	1157490.EL26_06940	3.941e-110	372.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,4HA0D@91061|Bacilli	91061|Bacilli	S	Zn-dependent proteases and their inactivated homologs	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
GZD3_k127_3905252_1	485913.Krac_8297	5.417e-61	222.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3905649_2	1382356.JQMP01000004_gene366	2.821e-81	274.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
GZD3_k127_3905649_0	204669.Acid345_3589	5.87e-118	392.0	2DUY4@1|root,33SYS@2|Bacteria,3Y6DP@57723|Acidobacteria,2JM0Z@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
GZD3_k127_3905649_1	485913.Krac_0962	3.136e-114	391.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
GZD3_k127_3905649_5	33876.JNXY01000007_gene8298	1.995e-07	62.0	COG4758@1|root,COG4758@2|Bacteria,2GMRP@201174|Actinobacteria,4DM7C@85008|Micromonosporales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
GZD3_k127_3905649_4	1254432.SCE1572_27630	1.128e-21	101.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,42W0S@68525|delta/epsilon subdivisions,2WRFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
GZD3_k127_3905649_3	446470.Snas_2965	2.04e-23	111.0	COG2133@1|root,COG3291@1|root,COG3506@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1349,GSDH,Ig_3,LGFP,PA14,PKD,fn3
GZD3_k127_3910296_10	479434.Sthe_2474	2.172e-20	94.0	COG0243@1|root,COG0243@2|Bacteria,2G62W@200795|Chloroflexi,27Z2M@189775|Thermomicrobia	189775|Thermomicrobia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
GZD3_k127_3910296_2	665952.HMPREF1015_01155	7.653e-102	350.0	COG2271@1|root,COG2271@2|Bacteria,1TRPU@1239|Firmicutes,4HBI9@91061|Bacilli,1ZD6G@1386|Bacillus	91061|Bacilli	G	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD3_k127_3910296_0	1123405.AUMM01000004_gene629	7.459e-186	596.0	COG0591@1|root,COG0591@2|Bacteria,1UZRF@1239|Firmicutes,4HGPN@91061|Bacilli	91061|Bacilli	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
GZD3_k127_3910296_12	189753.AXAS01000001_gene3872	7.926e-16	84.0	2EGF3@1|root,33A73@2|Bacteria,1N8EG@1224|Proteobacteria,2VGNY@28211|Alphaproteobacteria,3K1N5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
GZD3_k127_3910296_3	326427.Cagg_1199	2.522e-95	324.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi,376U9@32061|Chloroflexia	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_3910296_4	525904.Tter_2261	9.447e-72	248.0	COG0522@1|root,COG0522@2|Bacteria,2NPCC@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
GZD3_k127_3910296_7	1382306.JNIM01000001_gene1259	9.435e-41	169.0	COG2267@1|root,COG2267@2|Bacteria,2G6W2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_3910296_9	1382306.JNIM01000001_gene1260	5.049e-27	115.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
GZD3_k127_3910296_11	1382306.JNIM01000001_gene1261	4.766e-16	84.0	2DPVJ@1|root,333JK@2|Bacteria,2G9JX@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD3_k127_3910296_8	349161.Dred_2888	9.827e-32	137.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
GZD3_k127_3910296_6	485913.Krac_10958	1.249e-43	168.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
GZD3_k127_3910296_5	485913.Krac_10957	6.657e-71	251.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
GZD3_k127_391131_5	357808.RoseRS_0406	3.663e-43	163.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,3751B@32061|Chloroflexia	32061|Chloroflexia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
GZD3_k127_391131_8	518766.Rmar_2198	0.0001036	50.0	COG3255@1|root,COG3255@2|Bacteria,4NYB1@976|Bacteroidetes	976|Bacteroidetes	I	Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD3_k127_391131_1	1382306.JNIM01000001_gene3485	2.264e-84	291.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
GZD3_k127_391131_3	365528.KB891103_gene4176	1.524e-46	181.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4ETJ8@85013|Frankiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GZD3_k127_391131_6	1236902.ANAS01000013_gene1334	7.807e-41	159.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4EHU5@85012|Streptosporangiales	201174|Actinobacteria	GL	Phosphoglycerate mutase family	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
GZD3_k127_391131_0	330214.NIDE1834	3.291e-92	317.0	COG3547@1|root,COG3547@2|Bacteria,3J17W@40117|Nitrospirae	40117|Nitrospirae	L	hmm pf02371	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
GZD3_k127_391131_4	485913.Krac_12349	2.862e-44	180.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
GZD3_k127_391131_2	485913.Krac_8654	1.629e-49	192.0	COG0491@1|root,COG0491@2|Bacteria,2G7QF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_391131_7	1183438.GKIL_2106	2.638e-39	156.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
GZD3_k127_3918533_0	485913.Krac_1159	1.043e-256	844.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
GZD3_k127_3928301_0	485913.Krac_12562	8.435e-110	360.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
GZD3_k127_3928301_1	485913.Krac_1496	2.171e-40	153.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GZD3_k127_3929202_0	1382306.JNIM01000001_gene1940	1.929e-44	168.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
GZD3_k127_3940558_1	1429046.RR21198_2052	1.657e-127	415.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4FW2N@85025|Nocardiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD3_k127_3940558_3	1121946.AUAX01000016_gene4721	2.188e-122	398.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DB3C@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_3940558_2	485913.Krac_3535	1.577e-122	403.0	COG1846@1|root,COG1846@2|Bacteria,2G941@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
GZD3_k127_3940558_5	1226325.HMPREF1548_01123	0.0008163	48.0	2C4MH@1|root,33Z34@2|Bacteria,1VXNJ@1239|Firmicutes,24PWF@186801|Clostridia	186801|Clostridia	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
GZD3_k127_3940558_0	1382306.JNIM01000001_gene3374	4.284e-146	473.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi	200795|Chloroflexi	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GZD3_k127_3940558_4	1382356.JQMP01000003_gene1622	1.806e-103	347.0	COG0438@1|root,COG0438@2|Bacteria,2G8GB@200795|Chloroflexi,27XSA@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_3953746_1	1128421.JAGA01000002_gene261	8.951e-60	225.0	COG1319@1|root,COG1319@2|Bacteria,2NQUQ@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	yagS	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD3_k127_3953746_0	1128421.JAGA01000002_gene262	2.898e-218	701.0	COG1529@1|root,COG1529@2|Bacteria,2NPHP@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
GZD3_k127_3953746_2	1128421.JAGA01000002_gene263	1.28e-38	146.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,TAT_signal
GZD3_k127_3954680_0	263358.VAB18032_07475	1.147e-13	75.0	COG2823@1|root,COG2823@2|Bacteria,2IGN2@201174|Actinobacteria,4DFBV@85008|Micromonosporales	201174|Actinobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_3954680_1	1123368.AUIS01000008_gene2271	1.793e-08	59.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GZD3_k127_3956719_3	314278.NB231_05160	1.334e-12	73.0	COG1569@1|root,COG1569@2|Bacteria,1RE43@1224|Proteobacteria,1S40R@1236|Gammaproteobacteria,1WZSU@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GZD3_k127_3956719_2	1150399.AQYK01000001_gene2065	1.515e-15	87.0	COG0645@1|root,COG0645@2|Bacteria,2ITBC@201174|Actinobacteria	201174|Actinobacteria	J	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GZD3_k127_3956719_0	1382306.JNIM01000001_gene1265	1.328e-146	473.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
GZD3_k127_3956719_1	485913.Krac_11878	2.077e-63	236.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_11878|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_3962892_0	485913.Krac_3080	4.775e-59	212.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GZD3_k127_3962892_1	1283283.ATXA01000023_gene251	8.496e-49	179.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
GZD3_k127_3962892_2	345341.KUTG_08092	4.385e-14	73.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD3_k127_3993488_6	56110.Oscil6304_0181	1.11e-22	100.0	COG2402@1|root,COG2402@2|Bacteria,1G7M2@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2402 nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_3993488_5	485913.Krac_10932	6.658e-51	186.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
GZD3_k127_3993488_0	1382306.JNIM01000001_gene1878	0.0	1439.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
GZD3_k127_3993488_3	1382306.JNIM01000001_gene1877	2.381e-85	289.0	COG2872@1|root,COG2872@2|Bacteria	2|Bacteria	S	Ser-tRNA(Ala) hydrolase activity	alaS2	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872,ko:K07050	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
GZD3_k127_3993488_2	1382306.JNIM01000001_gene343	2.1e-133	443.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
GZD3_k127_3993488_4	485913.Krac_0782	1.707e-75	268.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_3993488_1	649638.Trad_1227	1.013e-150	491.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
GZD3_k127_3994315_4	1128421.JAGA01000002_gene1128	8.558e-05	47.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
GZD3_k127_3994315_1	1324957.K933_06548	1.562e-133	465.0	COG1002@1|root,arCOG03521@2157|Archaea,2XV4Z@28890|Euryarchaeota,23UGP@183963|Halobacteria	183963|Halobacteria	V	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
GZD3_k127_3994315_2	1173028.ANKO01000158_gene4529	1.779e-22	98.0	COG1598@1|root,COG1598@2|Bacteria,1G8ZM@1117|Cyanobacteria,1HD1M@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_3994315_3	63737.Npun_F3501	1.887e-08	58.0	COG1724@1|root,COG1724@2|Bacteria,1G8YW@1117|Cyanobacteria,1HT49@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_3994315_0	1382306.JNIM01000001_gene426	5.234e-220	691.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
GZD3_k127_3998576_2	479434.Sthe_1410	6.396e-57	203.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GZD3_k127_3998576_0	1382306.JNIM01000001_gene129	1.514e-85	294.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
GZD3_k127_3998576_1	1382306.JNIM01000001_gene130	3.653e-58	219.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
GZD3_k127_3998576_3	1382306.JNIM01000001_gene131	6.252e-38	162.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
GZD3_k127_3998576_4	1382306.JNIM01000001_gene133	2.71e-27	117.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
GZD3_k127_4021614_1	1382306.JNIM01000001_gene1645	6.331e-130	433.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	-	-	1.2.4.4	ko:K00166,ko:K00167,ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
GZD3_k127_4021614_7	485913.Krac_5451	1.196e-24	108.0	2DQ3G@1|root,334K8@2|Bacteria,2G77Z@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
GZD3_k127_4021614_5	485913.Krac_5449	1.547e-53	196.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GZD3_k127_4021614_4	1336243.JAEA01000011_gene3179	1.546e-82	283.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GZD3_k127_4021614_3	1382306.JNIM01000001_gene3365	1.338e-86	297.0	COG4280@1|root,COG4280@2|Bacteria,2G81A@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4021614_6	1382306.JNIM01000001_gene4068	2.799e-36	145.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene4068|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4021614_2	1382306.JNIM01000001_gene1266	2.519e-98	331.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD3_k127_4021614_0	269797.Mbar_A1195	2.809e-207	668.0	COG0855@1|root,arCOG04535@2157|Archaea,2XTCF@28890|Euryarchaeota,2N965@224756|Methanomicrobia	224756|Methanomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
GZD3_k127_4021614_8	1502851.FG93_03214	2.143e-15	87.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,3JTZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
GZD3_k127_40290_2	485913.Krac_11116	2.594e-84	286.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_40290_1	1382306.JNIM01000001_gene3648	7.63e-129	431.0	COG0661@1|root,COG0661@2|Bacteria,2G6DN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC-1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
GZD3_k127_40290_0	304371.MCP_1470	3.561e-141	462.0	COG2141@1|root,arCOG02410@2157|Archaea,2XUEF@28890|Euryarchaeota	28890|Euryarchaeota	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	fgd-2	-	1.1.98.2,1.1.98.5	ko:K15510,ko:K21835	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
GZD3_k127_4037346_2	383372.Rcas_0468	2.623e-30	137.0	COG1807@1|root,COG1807@2|Bacteria,2G7Q8@200795|Chloroflexi,3782W@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4037346_0	485913.Krac_1276	6.349e-137	440.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GZD3_k127_4038708_3	1382306.JNIM01000001_gene1289	1.641e-70	247.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GZD3_k127_4038708_4	485915.Dret_0555	5.001e-70	244.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,2M92Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
GZD3_k127_4038708_1	1382356.JQMP01000004_gene669	2.358e-153	498.0	COG1220@1|root,COG1220@2|Bacteria,2GBH6@200795|Chloroflexi,27XKZ@189775|Thermomicrobia	189775|Thermomicrobia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	-	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
GZD3_k127_4038708_0	1382306.JNIM01000001_gene1536	6.725e-196	616.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi	200795|Chloroflexi	E	Methionine synthase vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
GZD3_k127_4038708_6	395961.Cyan7425_1818	6.621e-15	85.0	COG5464@1|root,COG5464@2|Bacteria,1FZUW@1117|Cyanobacteria,3KHM1@43988|Cyanothece	1117|Cyanobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
GZD3_k127_4038708_2	1382306.JNIM01000001_gene1024	5.539e-89	304.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD3_k127_4038708_5	485913.Krac_2434	4.675e-66	229.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
GZD3_k127_4053208_1	485913.Krac_4836	8.385e-96	318.0	COG0500@1|root,COG2226@2|Bacteria,2G9AJ@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase type 11	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
GZD3_k127_4053208_2	485913.Krac_4837	8.146e-80	273.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	2|Bacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
GZD3_k127_4069674_3	479434.Sthe_0042	5.545e-66	230.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2G87I@200795|Chloroflexi,27YW4@189775|Thermomicrobia	189775|Thermomicrobia	H	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
GZD3_k127_4069674_1	479434.Sthe_0041	1.38e-83	286.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi,27Z4Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GZD3_k127_4069674_4	479434.Sthe_0040	3.378e-58	213.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,27Z60@189775|Thermomicrobia	189775|Thermomicrobia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GZD3_k127_4069674_0	479434.Sthe_0039	1.24e-122	409.0	COG3835@1|root,COG3835@2|Bacteria,2GBDP@200795|Chloroflexi,27YZM@189775|Thermomicrobia	189775|Thermomicrobia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
GZD3_k127_4069674_6	479434.Sthe_1381	2.93e-15	89.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,LysM
GZD3_k127_4069674_5	1122223.KB890696_gene81	1.361e-22	111.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1WID8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
GZD3_k127_4069674_2	1382306.JNIM01000001_gene2027	1.957e-68	240.0	COG1230@1|root,COG1230@2|Bacteria,2G6FI@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
GZD3_k127_4071631_2	1382306.JNIM01000001_gene2768	2.814e-119	400.0	28JU5@1|root,2Z9J8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
GZD3_k127_4071631_4	345341.KUTG_09130	9.805e-06	58.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
GZD3_k127_4071631_0	1382306.JNIM01000001_gene1374	1.005e-221	702.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GZD3_k127_4071631_1	351607.Acel_1068	4.846e-202	639.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD3_k127_4072650_4	1382306.JNIM01000001_gene4038	1.74e-78	273.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
GZD3_k127_4072650_7	479434.Sthe_1104	1.664e-47	182.0	COG1877@1|root,COG1877@2|Bacteria,2G6X2@200795|Chloroflexi,27YHH@189775|Thermomicrobia	189775|Thermomicrobia	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
GZD3_k127_4072650_2	478741.JAFS01000002_gene509	3.24e-102	348.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,46WTS@74201|Verrucomicrobia,37G3H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GZD3_k127_4072650_1	273057.SSO2130	1.808e-135	440.0	COG1013@1|root,arCOG01601@2157|Archaea,2XPVE@28889|Crenarchaeota	28889|Crenarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
GZD3_k127_4072650_0	266117.Rxyl_0920	3.598e-153	497.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
GZD3_k127_4072650_3	273057.SSO2128	2.499e-101	343.0	COG1144@1|root,arCOG01604@2157|Archaea,2XRKM@28889|Crenarchaeota	28889|Crenarchaeota	C	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like)	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_21
GZD3_k127_4072650_6	266117.Rxyl_0929	1.198e-51	197.0	COG2186@1|root,COG2186@2|Bacteria,2HGSA@201174|Actinobacteria,4CTGZ@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein GntR HTH	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
GZD3_k127_4072650_5	485913.Krac_12596	4.399e-77	266.0	COG0730@1|root,COG0730@2|Bacteria,2G6RC@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
GZD3_k127_4072650_9	309801.trd_1345	0.0006429	45.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_4081393_2	485913.Krac_5405	6.926e-34	149.0	2CC95@1|root,2Z8VE@2|Bacteria,2G92N@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4081393_1	506534.Rhein_3047	1.508e-50	186.0	2ECM6@1|root,336J7@2|Bacteria,1Q5ZA@1224|Proteobacteria,1ST2F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4081393_0	285535.JOEY01000057_gene6481	8.388e-110	362.0	COG0104@1|root,COG0104@2|Bacteria,2IERH@201174|Actinobacteria	201174|Actinobacteria	F	Adenylosuccinate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Adenylsucc_synt
GZD3_k127_4086646_3	926550.CLDAP_02510	8.914e-15	82.0	COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi	200795|Chloroflexi	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GZD3_k127_4086646_1	1183438.GKIL_0022	4.325e-81	280.0	COG0596@1|root,COG0596@2|Bacteria,1G2DE@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_4086646_0	292459.STH1137	3.021e-126	412.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD3_k127_4086646_2	1382306.JNIM01000001_gene3560	2.553e-55	198.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
GZD3_k127_4096983_0	485913.Krac_7619	2.778e-227	723.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
GZD3_k127_4096983_6	1382306.JNIM01000001_gene963	1.359e-54	199.0	COG0193@1|root,COG1082@1|root,COG0193@2|Bacteria,COG1082@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
GZD3_k127_4096983_5	1382306.JNIM01000001_gene1812	8.159e-80	276.0	COG0461@1|root,COG0461@2|Bacteria,2G7HB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
GZD3_k127_4096983_2	1410619.SRDD_05240	1.14e-161	518.0	28K06@1|root,2Z9Q5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4096983_4	1382306.JNIM01000001_gene1811	2.641e-98	330.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GZD3_k127_4096983_3	1382306.JNIM01000001_gene1810	3.598e-115	391.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
GZD3_k127_4096983_1	485913.Krac_8225	5.843e-179	576.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
GZD3_k127_4096983_7	177437.HRM2_07910	3.59e-15	81.0	COG0726@1|root,COG0726@2|Bacteria,1RH3I@1224|Proteobacteria,42T75@68525|delta/epsilon subdivisions,2WPC1@28221|Deltaproteobacteria,2MK87@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Archaea-specific editing domain of threonyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-Thr_ED
GZD3_k127_4098292_0	485913.Krac_7601	3.624e-210	664.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
GZD3_k127_4098292_2	309801.trd_1757	7.071e-24	104.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,27YK5@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
GZD3_k127_4098292_3	751945.Theos_0794	1.501e-20	97.0	COG1254@1|root,COG1254@2|Bacteria,1WK7T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
GZD3_k127_4098292_1	266117.Rxyl_1048	9.015e-50	185.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	doxD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
GZD3_k127_4098292_4	479431.Namu_5329	4.169e-09	69.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4EXGY@85013|Frankiales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GZD3_k127_4125182_5	1382306.JNIM01000001_gene1066	1.198e-28	130.0	COG0642@1|root,COG2205@2|Bacteria	1382306.JNIM01000001_gene1066|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4125182_4	485913.Krac_10950	1.719e-30	136.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_10950|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4125182_2	1144275.COCOR_05647	2.069e-83	294.0	COG1231@1|root,COG1231@2|Bacteria,1MUPQ@1224|Proteobacteria,4383I@68525|delta/epsilon subdivisions,2X3DH@28221|Deltaproteobacteria,2YVJA@29|Myxococcales	28221|Deltaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD3_k127_4125182_6	43989.cce_4998	2.347e-21	100.0	COG4113@1|root,COG4113@2|Bacteria,1G7F7@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_4125182_3	485913.Krac_1169	1.614e-68	244.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_4125182_7	485913.Krac_0300	4.26e-20	94.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_4125182_9	1120980.JQKH01000049_gene1830	6.907e-05	55.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,2KPKP@206351|Neisseriales	206351|Neisseriales	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_4125182_0	1382306.JNIM01000001_gene2523	3.097e-173	552.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
GZD3_k127_4125182_1	1382306.JNIM01000001_gene2524	4.479e-127	411.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
GZD3_k127_4142056_7	479434.Sthe_2667	5.701e-16	89.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_4142056_0	485913.Krac_4955	2.891e-57	207.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GZD3_k127_4142056_3	485913.Krac_9928	1.253e-44	177.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_9928|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4142056_8	543526.Htur_1021	4.643e-08	65.0	COG0642@1|root,COG2203@1|root,arCOG02352@1|root,arCOG02359@1|root,arCOG03567@1|root,arCOG02352@2157|Archaea,arCOG02358@2157|Archaea,arCOG02359@2157|Archaea,arCOG02369@2157|Archaea,arCOG03567@2157|Archaea,2XUM1@28890|Euryarchaeota,23UN4@183963|Halobacteria	183963|Halobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS_3,PAS_4
GZD3_k127_4142056_4	485913.Krac_4955	1.367e-31	141.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
GZD3_k127_4142056_1	1382306.JNIM01000001_gene2393	6.636e-53	204.0	COG5002@1|root,COG5002@2|Bacteria,2G66G@200795|Chloroflexi	2|Bacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
GZD3_k127_4142056_2	485913.Krac_4956	2.605e-48	177.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4142056_5	485913.Krac_4956	5.04e-29	128.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4142056_6	1196028.ALEF01000043_gene524	6.548e-23	99.0	COG2132@1|root,COG2132@2|Bacteria,1V0S4@1239|Firmicutes,4HESB@91061|Bacilli	91061|Bacilli	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
GZD3_k127_4145117_0	251229.Chro_0856	4.228e-64	223.0	COG1131@1|root,COG1131@2|Bacteria,1G1P6@1117|Cyanobacteria,3VHUZ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_4145117_2	926550.CLDAP_35520	2.425e-26	123.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
GZD3_k127_4145117_3	1463881.KL591022_gene1523	1.529e-13	81.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
GZD3_k127_4145117_4	690850.Desaf_2361	1.07e-12	75.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_4145117_5	196164.23492786	7.594e-07	58.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,22K1X@1653|Corynebacteriaceae	201174|Actinobacteria	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4145117_1	1278073.MYSTI_01501	1.403e-30	137.0	COG0542@1|root,COG1186@1|root,COG0542@2|Bacteria,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	-	-	-	ko:K02839,ko:K03694,ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03012,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,OMP_b-brl,PCRF
GZD3_k127_4168391_3	485913.Krac_11183	8.747e-35	145.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GZD3_k127_4168391_0	1382306.JNIM01000001_gene3583	1.697e-164	542.0	COG0578@1|root,COG0578@2|Bacteria	2|Bacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
GZD3_k127_4168391_2	1382306.JNIM01000001_gene680	2.475e-123	419.0	COG0323@1|root,COG0323@2|Bacteria,2G8BQ@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c,HATPase_c_3,MutL_C
GZD3_k127_4168391_1	479434.Sthe_0669	3.072e-163	541.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
GZD3_k127_4195637_1	1382306.JNIM01000001_gene639	1.641e-38	157.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_4195637_0	1382306.JNIM01000001_gene980	1.106e-60	228.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
GZD3_k127_4197549_0	1120971.AUCA01000015_gene330	3.504e-72	246.0	COG1028@1|root,COG1028@2|Bacteria,1TS0K@1239|Firmicutes,4HA78@91061|Bacilli	91061|Bacilli	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_4197549_1	1122179.KB890438_gene1532	4.676e-56	207.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1IXIF@117747|Sphingobacteriia	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD3_k127_4198866_1	1382306.JNIM01000001_gene2147	1.482e-43	166.0	COG0500@1|root,COG2226@2|Bacteria,2G9SY@200795|Chloroflexi	2|Bacteria	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD3_k127_4198866_2	1123401.JHYQ01000012_gene2954	9.567e-38	144.0	COG4634@1|root,COG4634@2|Bacteria,1N11T@1224|Proteobacteria,1SHBJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
GZD3_k127_4198866_3	383372.Rcas_0712	4.84e-29	117.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
GZD3_k127_4198866_0	485913.Krac_6839	9.923e-64	223.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
GZD3_k127_4199526_1	224325.AF_1426	5.996e-43	168.0	COG0580@1|root,arCOG04431@2157|Archaea,2XT1N@28890|Euryarchaeota,245ZS@183980|Archaeoglobi	183980|Archaeoglobi	P	Major intrinsic protein	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
GZD3_k127_4199526_2	1382306.JNIM01000001_gene780	2.414e-42	160.0	2DN66@1|root,32VSD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
GZD3_k127_4199526_0	926560.KE387023_gene2484	1.17e-70	247.0	COG1028@1|root,COG1028@2|Bacteria	926560.KE387023_gene2484|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4199526_3	1382306.JNIM01000001_gene151	4.265e-09	57.0	COG1522@1|root,COG1522@2|Bacteria,2G99D@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
GZD3_k127_4204865_0	485913.Krac_8955	2.309e-123	399.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
GZD3_k127_4204865_2	1382306.JNIM01000001_gene97	1.652e-52	200.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
GZD3_k127_4204865_1	1297742.A176_04480	5.696e-85	285.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42UAF@68525|delta/epsilon subdivisions,2WQGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
GZD3_k127_4218726_2	485913.Krac_9162	9.088e-28	114.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
GZD3_k127_4218726_1	485913.Krac_9160	1.067e-42	162.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
GZD3_k127_4219366_1	485913.Krac_1203	2.978e-181	582.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GZD3_k127_4219366_0	1382306.JNIM01000001_gene1922	2.523e-190	602.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	-	-	-	-	-	-	-	-	-	-	-	-	Adenylsucc_synt
GZD3_k127_4226620_5	1397699.JNIS01000001_gene1472	1.436e-08	67.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,4HB7F@91061|Bacilli	91061|Bacilli	S	FAD-dependent	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8
GZD3_k127_4226620_3	179408.Osc7112_1785	9.416e-14	76.0	COG1598@1|root,COG1598@2|Bacteria,1G7VX@1117|Cyanobacteria,1HC4M@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_4226620_7	1147.D082_27220	1.623e-06	52.0	COG1598@1|root,COG1598@2|Bacteria,1GIJ2@1117|Cyanobacteria,1H6TS@1142|Synechocystis	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4226620_6	489825.LYNGBM3L_03850	5.856e-08	57.0	COG1724@1|root,COG1724@2|Bacteria,1G8YW@1117|Cyanobacteria,1HD4D@1150|Oscillatoriales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_4226620_0	266117.Rxyl_2393	4.84e-97	332.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_4226620_1	322710.Avin_33500	1.252e-90	312.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,1S17T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	TIGRFAM Esterase, PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
GZD3_k127_4226620_8	356851.JOAN01000002_gene717	1.681e-05	50.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4DDTU@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_4226620_2	266117.Rxyl_2392	3.885e-44	165.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	phaQ	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_4232423_0	263358.VAB18032_08330	3.263e-211	666.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DMJF@85008|Micromonosporales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
GZD3_k127_4232423_1	909613.UO65_5742	6.1e-49	189.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria,4E08I@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_4232423_3	926569.ANT_12300	4.433e-24	103.0	COG3293@1|root,COG3293@2|Bacteria,2G9EK@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
GZD3_k127_4232423_2	485913.Krac_9652	4.478e-33	132.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
GZD3_k127_4240733_2	1075090.GOAMR_15_00500	3.139e-05	54.0	2CGGK@1|root,2ZXKT@2|Bacteria,2GX1V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4240733_0	867903.ThesuDRAFT_01294	1.154e-104	349.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3WDS3@538999|Clostridiales incertae sedis	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
GZD3_k127_4240733_1	479432.Sros_4688	1.453e-24	106.0	COG2963@1|root,COG2963@2|Bacteria,2IM4Y@201174|Actinobacteria,4EPTR@85012|Streptosporangiales	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
GZD3_k127_4244193_1	485913.Krac_2641	7.861e-104	349.0	COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi	200795|Chloroflexi	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
GZD3_k127_4244193_2	1280950.HJO_12801	2.035e-08	65.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria,43XPN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AurF
GZD3_k127_4244193_0	1095769.CAHF01000005_gene1456	1.666e-183	586.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VJFS@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GZD3_k127_4246728_5	189753.AXAS01000009_gene6373	1.493e-31	130.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2UFVV@28211|Alphaproteobacteria,3JYW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
GZD3_k127_4246728_1	485913.Krac_5655	5.339e-141	462.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_4246728_3	485913.Krac_7202	7.943e-111	376.0	COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi	2|Bacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_4246728_4	485913.Krac_5359	1.25e-32	130.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_4246728_6	1356854.N007_11050	3.54e-23	112.0	2EUC9@1|root,33MUN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4246728_0	485913.Krac_8046	1.143e-154	521.0	COG3127@1|root,COG3127@2|Bacteria,2G7QS@200795|Chloroflexi	200795|Chloroflexi	Q	COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
GZD3_k127_4246728_2	1382306.JNIM01000001_gene857	4.032e-120	394.0	COG1131@1|root,COG1131@2|Bacteria,2G7YX@200795|Chloroflexi	200795|Chloroflexi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GZD3_k127_4246728_8	485913.Krac_12238	0.0002229	48.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
GZD3_k127_424802_1	357808.RoseRS_1632	4.079e-64	230.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi,375F4@32061|Chloroflexia	32061|Chloroflexia	I	diacylglycerol kinase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD3_k127_424802_3	1121472.AQWN01000002_gene2099	1.56e-27	126.0	COG4191@1|root,COG4191@2|Bacteria,1UMSI@1239|Firmicutes,25GPV@186801|Clostridia,267GQ@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
GZD3_k127_424802_6	1449347.JQLN01000001_gene318	4.497e-05	55.0	COG3861@1|root,COG3861@2|Bacteria,2IJ72@201174|Actinobacteria	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
GZD3_k127_424802_0	485913.Krac_6502	2.646e-93	316.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,LTD,PKD,Pro-kuma_activ,fn3
GZD3_k127_424802_4	357808.RoseRS_3598	1.966e-22	103.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,375T7@32061|Chloroflexia	32061|Chloroflexia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
GZD3_k127_424802_2	485913.Krac_10064	3.041e-48	190.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
GZD3_k127_424802_7	1118057.CAGX01000042_gene539	0.0003497	47.0	COG2755@1|root,COG2755@2|Bacteria,1VCGV@1239|Firmicutes,24T8J@186801|Clostridia,22J09@1570339|Peptoniphilaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4262957_5	298655.KI912266_gene38	1.503e-06	55.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,2GMB5@201174|Actinobacteria	201174|Actinobacteria	T	PFAM Metallophosphoesterase	prpA	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
GZD3_k127_4262957_1	1382306.JNIM01000001_gene124	2.853e-50	195.0	28HQ3@1|root,2Z7XW@2|Bacteria,2G9Q4@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
GZD3_k127_4262957_2	997296.PB1_06262	6.747e-47	175.0	COG0640@1|root,COG0640@2|Bacteria,1VCMI@1239|Firmicutes,4HJJ5@91061|Bacilli,1ZHF7@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GZD3_k127_4262957_0	255470.cbdbA1715	3.296e-81	282.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD3_k127_4262957_3	1280692.AUJL01000009_gene2915	1.172e-23	108.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,24HPX@186801|Clostridia,36J6R@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
GZD3_k127_4341013_1	485913.Krac_11295	1.085e-36	144.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
GZD3_k127_4363103_1	383372.Rcas_1303	1.286e-123	401.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_4363103_4	1449353.JQMQ01000005_gene591	1.286e-32	137.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,2NJ55@228398|Streptacidiphilus	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
GZD3_k127_4363103_2	1041146.ATZB01000012_gene3199	4.817e-57	208.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2U7DU@28211|Alphaproteobacteria,4BEH0@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
GZD3_k127_4363103_0	485913.Krac_12565	1.263e-226	716.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
GZD3_k127_4363103_3	1382306.JNIM01000001_gene1001	4.013e-52	198.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GZD3_k127_4363103_5	196162.Noca_2547	9.311e-30	125.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
GZD3_k127_4365966_0	1382306.JNIM01000001_gene3879	2.334e-171	551.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
GZD3_k127_4365966_2	485913.Krac_8748	2.182e-23	108.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
GZD3_k127_4365966_4	391612.CY0110_25431	2.341e-13	76.0	COG2442@1|root,COG2442@2|Bacteria,1G71J@1117|Cyanobacteria,3KIYI@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4365966_3	1173264.KI913951_gene4677	1.374e-21	98.0	COG4634@1|root,COG4634@2|Bacteria,1G7CU@1117|Cyanobacteria,1HBSZ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4365966_1	1382306.JNIM01000001_gene526	3.269e-29	117.0	COG0515@1|root,COG1199@1|root,COG0515@2|Bacteria,COG1199@2|Bacteria,2G88S@200795|Chloroflexi	200795|Chloroflexi	KLT	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,Pkinase
GZD3_k127_4367557_2	1382306.JNIM01000001_gene3779	5.056e-81	287.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
GZD3_k127_4367557_6	102232.GLO73106DRAFT_00032540	4.543e-21	99.0	2F9DS@1|root,341QN@2|Bacteria,1GECM@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4367557_7	102232.GLO73106DRAFT_00032550	3.373e-09	68.0	2F8MW@1|root,3410C@2|Bacteria,1GEKQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4367557_3	485913.Krac_2065	3.346e-65	239.0	COG3246@1|root,COG3246@2|Bacteria	2|Bacteria	K	L-lysine catabolic process to acetate	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
GZD3_k127_4367557_1	103733.JNYO01000020_gene1878	2.726e-121	405.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4DXPK@85010|Pseudonocardiales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
GZD3_k127_4367557_0	1183438.GKIL_2947	9.342e-207	659.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria	1117|Cyanobacteria	KOT	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
GZD3_k127_4367557_4	1382306.JNIM01000001_gene3756	3.057e-51	184.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GZD3_k127_4390213_2	485913.Krac_8502	5.067e-81	271.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GZD3_k127_4390213_7	1382306.JNIM01000001_gene201	3.252e-22	98.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
GZD3_k127_4390213_1	485913.Krac_8503	9.582e-99	330.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
GZD3_k127_4390213_0	1382306.JNIM01000001_gene199	8.49e-236	736.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
GZD3_k127_4390213_5	1382306.JNIM01000001_gene198	4.53e-33	134.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
GZD3_k127_4390213_4	105420.BBPO01000002_gene7460	4.074e-44	169.0	2CCBF@1|root,34AAG@2|Bacteria,2H8AD@201174|Actinobacteria,2NJQN@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4390213_3	1408418.JNJH01000006_gene1284	1.944e-73	261.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	cysP	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306,ko:K16331	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.4	-	-	PHO4
GZD3_k127_4390213_6	485913.Krac_4041	2.464e-29	123.0	COG0537@1|root,COG0607@1|root,COG4283@1|root,COG0537@2|Bacteria,COG0607@2|Bacteria,COG4283@2|Bacteria,2G8I6@200795|Chloroflexi	200795|Chloroflexi	KP	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Rhodanese
GZD3_k127_4403648_2	1386089.N865_20090	2.438e-26	112.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4FFC5@85021|Intrasporangiaceae	201174|Actinobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_4403648_3	448385.sce1522	0.0001706	54.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD3_k127_4403648_1	66373.JOFQ01000001_gene1747	2.016e-58	217.0	COG0385@1|root,COG0385@2|Bacteria,2GNES@201174|Actinobacteria	201174|Actinobacteria	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
GZD3_k127_4403648_0	42256.RradSPS_0358	3.386e-123	424.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
GZD3_k127_446109_0	485913.Krac_7342	1.319e-83	289.0	2DWX5@1|root,342BS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4490561_1	523845.AQXV01000046_gene819	2.177e-17	95.0	COG1305@1|root,arCOG03600@2157|Archaea,2Y860@28890|Euryarchaeota,23RG6@183939|Methanococci	183939|Methanococci	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4490561_0	485913.Krac_12186	1.815e-34	149.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Yop-YscD_cpl
GZD3_k127_4531917_0	28444.JODQ01000001_gene2747	1.424e-112	403.0	COG2133@1|root,COG3291@1|root,COG3506@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,F5_F8_type_C,GSDH,Ig_3,LGFP,PA14,PKD,fn3
GZD3_k127_453935_2	83406.HDN1F_29120	2.118e-06	58.0	COG1092@1|root,COG1092@2|Bacteria,1RJR8@1224|Proteobacteria,1S69T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
GZD3_k127_453935_0	196162.Noca_3615	3.595e-80	278.0	COG0451@1|root,COG0451@2|Bacteria,2I1PI@201174|Actinobacteria,4DUKC@85009|Propionibacteriales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
GZD3_k127_453935_1	479434.Sthe_0254	7.326e-74	256.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,27XTA@189775|Thermomicrobia	189775|Thermomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
GZD3_k127_4539987_1	1382306.JNIM01000001_gene723	7.902e-19	87.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
GZD3_k127_4539987_0	1370121.AUWS01000097_gene3462	4.335e-102	341.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,235ZJ@1762|Mycobacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD3_k127_4539987_2	1122239.AULS01000014_gene2272	1.301e-16	83.0	COG0702@1|root,COG0702@2|Bacteria,2I470@201174|Actinobacteria,4FS5F@85023|Microbacteriaceae	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
GZD3_k127_455428_1	383372.Rcas_3302	9.124e-82	286.0	COG5551@1|root,COG5551@2|Bacteria,2G6UR@200795|Chloroflexi,376CK@32061|Chloroflexia	32061|Chloroflexia	S	Pfam:DUF2276	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
GZD3_k127_455428_0	1382306.JNIM01000001_gene2062	5.351e-124	409.0	COG1518@1|root,COG1518@2|Bacteria,2G5P1@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
GZD3_k127_455428_3	1382306.JNIM01000001_gene2063	6.103e-20	93.0	COG1343@1|root,COG1343@2|Bacteria,2G783@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
GZD3_k127_455428_2	326427.Cagg_0565	3.777e-62	225.0	COG1468@1|root,COG1468@2|Bacteria,2G6U0@200795|Chloroflexi,376SW@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM CRISPR-associated protein Cas4	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
GZD3_k127_4558047_10	1128421.JAGA01000004_gene2627	5.205e-60	215.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GZD3_k127_4558047_3	485913.Krac_2115	2.518e-125	413.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
GZD3_k127_4558047_5	1382306.JNIM01000001_gene3206	3.843e-106	358.0	COG4214@1|root,COG4214@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
GZD3_k127_4558047_6	272134.KB731324_gene4817	4.919e-105	348.0	COG1129@1|root,COG1129@2|Bacteria,1GQ25@1117|Cyanobacteria,1H732@1150|Oscillatoriales	1117|Cyanobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
GZD3_k127_4558047_1	1382306.JNIM01000001_gene3204	2.69e-129	424.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
GZD3_k127_4558047_2	1382306.JNIM01000001_gene2416	1.418e-126	419.0	COG1940@1|root,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
GZD3_k127_4558047_9	1382306.JNIM01000001_gene2488	1.203e-78	288.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	EAL,GAF,GGDEF,HATPase_c,HTH_18,HisKA,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
GZD3_k127_4558047_0	1382306.JNIM01000001_gene2527	1.439e-141	475.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
GZD3_k127_4558047_8	1382306.JNIM01000001_gene2526	2.282e-83	287.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_4558047_4	1382306.JNIM01000001_gene343	1.294e-121	410.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
GZD3_k127_4558047_7	264732.Moth_1131	1.796e-83	285.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,42EYI@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4558047_12	1382306.JNIM01000001_gene733	4.063e-18	96.0	COG5002@1|root,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_4559346_1	1382306.JNIM01000001_gene295	1.176e-46	188.0	COG0642@1|root,COG2205@2|Bacteria	1382306.JNIM01000001_gene295|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4559346_5	1121943.KB899999_gene1353	3.312e-13	75.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XI3Y@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes	glnG	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_4559346_2	485913.Krac_12253	6.478e-23	101.0	29684@1|root,2ZTI4@2|Bacteria,2G9NR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4559346_0	479434.Sthe_1115	4.662e-135	447.0	COG2204@1|root,COG2204@2|Bacteria,2G5ZP@200795|Chloroflexi	200795|Chloroflexi	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_4559346_6	1123320.KB889662_gene1645	8.316e-10	71.0	COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria	201174|Actinobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4559346_3	926560.KE387025_gene4121	5.702e-22	99.0	COG3335@1|root,COG3335@2|Bacteria,1WJVK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_4565474_1	1123354.AUDR01000012_gene1855	2.462e-45	177.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2VRED@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_4565474_0	1173028.ANKO01000015_gene4601	2.142e-143	461.0	COG0863@1|root,COG0863@2|Bacteria,1GQV8@1117|Cyanobacteria,1HI24@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
GZD3_k127_4566324_0	525904.Tter_0383	1.539e-29	126.0	COG0071@1|root,COG0071@2|Bacteria,2NPXZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_4566324_1	525904.Tter_0223	3.635e-16	84.0	COG0766@1|root,COG0766@2|Bacteria,2NNUV@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
GZD3_k127_4567397_3	1379698.RBG1_1C00001G0708	7.568e-74	260.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GZD3_k127_4567397_12	159749.K0S810	0.0001505	51.0	2F4T4@1|root,2T5T9@2759|Eukaryota,2XFAH@2836|Bacillariophyta	2836|Bacillariophyta	S	Complex I intermediate-associated protein 30 (CIA30)	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
GZD3_k127_4567397_2	479434.Sthe_1533	6.592e-101	340.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,27YWI@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD3_k127_4567397_0	1414720.CBYM010000019_gene2471	1.688e-197	658.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,36DGD@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
GZD3_k127_4567397_4	1382306.JNIM01000001_gene3445	2.628e-67	237.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
GZD3_k127_4567397_5	326427.Cagg_2909	2.987e-67	240.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,376FG@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
GZD3_k127_4567397_6	760117.JN27_19955	9.712e-32	135.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VQBN@28216|Betaproteobacteria,47742@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Bacterial sugar transferase	bplG	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
GZD3_k127_4567397_7	240015.ACP_1942	2.954e-29	127.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yvaF	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K09017,ko:K22105	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GZD3_k127_4567397_1	1380390.JIAT01000009_gene2065	1.432e-114	389.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4567397_10	666685.R2APBS1_3556	1.211e-07	64.0	29SH7@1|root,30DN9@2|Bacteria,1QM17@1224|Proteobacteria,1SQW6@1236|Gammaproteobacteria,1X50V@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4567397_8	485913.Krac_10931	9.625e-26	113.0	2EV68@1|root,33NM1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4567397_9	1122609.AUGT01000009_gene3024	5.631e-15	78.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4DS21@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
GZD3_k127_4569593_0	1382306.JNIM01000001_gene3647	6.085e-225	719.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Peptidase_M1
GZD3_k127_4578756_1	525904.Tter_0931	9.499e-144	466.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475	TGT
GZD3_k127_4578756_9	118168.MC7420_3784	3.168e-05	53.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4578756_6	32057.KB217478_gene5965	3.866e-38	147.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HNP6@1161|Nostocales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GZD3_k127_4578756_5	485913.Krac_8809	3.251e-42	160.0	COG1716@1|root,COG1716@2|Bacteria,2G8U3@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA
GZD3_k127_4578756_0	1382306.JNIM01000001_gene4046	3.206e-154	498.0	COG2304@1|root,COG2304@2|Bacteria,2G82P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
GZD3_k127_4578756_3	1382306.JNIM01000001_gene4045	1.807e-81	293.0	COG0631@1|root,COG0631@2|Bacteria,2G8I1@200795|Chloroflexi	200795|Chloroflexi	T	Protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
GZD3_k127_4578756_2	1382306.JNIM01000001_gene4044	5.692e-97	340.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase,TPR_8
GZD3_k127_4578756_4	1382306.JNIM01000001_gene4043	6.408e-74	264.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,Pkinase
GZD3_k127_4578756_7	1382356.JQMP01000003_gene1852	9.968e-33	129.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi,27YJD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
GZD3_k127_4578756_8	717605.Theco_2537	5.628e-31	128.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,26YFK@186822|Paenibacillaceae	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
GZD3_k127_4579916_5	562970.Btus_1326	4.594e-92	310.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,277XQ@186823|Alicyclobacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
GZD3_k127_4579916_4	1382306.JNIM01000001_gene514	2.345e-114	381.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
GZD3_k127_4579916_12	485913.Krac_11753	2.737e-28	128.0	COG1716@1|root,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD3_k127_4579916_3	1382306.JNIM01000001_gene517	1.603e-116	387.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene517|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4579916_8	1382306.JNIM01000001_gene1060	6.406e-60	213.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
GZD3_k127_4579916_0	485913.Krac_6638	1.037e-167	565.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
GZD3_k127_4579916_15	318586.Pden_3177	1.583e-08	59.0	COG2002@1|root,COG2002@2|Bacteria,1N7NX@1224|Proteobacteria,2UKQV@28211|Alphaproteobacteria,2PXJW@265|Paracoccus	28211|Alphaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
GZD3_k127_4579916_14	429009.Adeg_1056	5.529e-17	86.0	COG1848@1|root,COG1848@2|Bacteria,1UK2G@1239|Firmicutes	1239|Firmicutes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_4579916_6	1440053.JOEI01000005_gene1859	5.727e-79	268.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
GZD3_k127_4579916_9	996637.SGM_4594	7.873e-50	190.0	28JCJ@1|root,2Z977@2|Bacteria,2GJVA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4579916_2	1144275.COCOR_02429	2.142e-134	443.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X2MT@28221|Deltaproteobacteria,2YTVU@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GZD3_k127_4579916_11	316274.Haur_0626	5.946e-37	151.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,377W5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_4579916_7	1329516.JPST01000035_gene3113	3.114e-73	254.0	COG0225@1|root,COG0225@2|Bacteria,1V4HF@1239|Firmicutes,4HHQM@91061|Bacilli,27BQ3@186824|Thermoactinomycetaceae	91061|Bacilli	O	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
GZD3_k127_4579916_1	1382306.JNIM01000001_gene3645	3.792e-152	484.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
GZD3_k127_4581217_10	397291.C804_03269	7.376e-08	56.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,27JIY@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
GZD3_k127_4581217_6	485913.Krac_12006	7.563e-72	262.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4581217_7	1382306.JNIM01000001_gene210	3.478e-38	150.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
GZD3_k127_4581217_8	1127134.NOCYR_3960	3.535e-26	113.0	COG0346@1|root,COG0346@2|Bacteria,2IQUP@201174|Actinobacteria,4G1DP@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_4581217_1	266117.Rxyl_2946	8.148e-140	474.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
GZD3_k127_4581217_5	58344.JOEL01000022_gene988	2.958e-83	289.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
GZD3_k127_4581217_2	1051632.TPY_1071	1.08e-118	390.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CYU@186801|Clostridia	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
GZD3_k127_4581217_4	485913.Krac_7792	7.803e-88	297.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_4581217_0	562970.Btus_1243	6.874e-167	539.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD3_k127_4581217_3	1382306.JNIM01000001_gene330	1.002e-103	343.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GZD3_k127_4581217_9	485913.Krac_12471	1.446e-17	83.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
GZD3_k127_4598103_1	526227.Mesil_1024	2.775e-50	181.0	COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GZD3_k127_4598103_2	479434.Sthe_0094	1.732e-23	111.0	COG1595@1|root,COG1595@2|Bacteria,2G9AH@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_4598103_0	485913.Krac_8519	3.179e-100	338.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
GZD3_k127_4603381_1	290397.Adeh_3931	1.139e-17	87.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria	1224|Proteobacteria	E	PFAM homoserine dehydrogenase	metL	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
GZD3_k127_4603381_0	1382306.JNIM01000001_gene3885	1.809e-270	857.0	COG0072@1|root,COG0072@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
GZD3_k127_4609643_1	1120934.KB894422_gene2855	6.094e-17	89.0	COG1846@1|root,COG1846@2|Bacteria,2HKWC@201174|Actinobacteria,4ECID@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4609643_0	1454010.JEOE01000001_gene880	1.861e-127	416.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
GZD3_k127_4611316_1	35754.JNYJ01000008_gene3271	7.182e-46	171.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria,4DEAY@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
GZD3_k127_4611316_0	479434.Sthe_0072	4e-111	396.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
GZD3_k127_4611316_2	313596.RB2501_09335	1.511e-08	66.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4612381_6	768671.ThimaDRAFT_3622	2.181e-18	93.0	COG0789@1|root,COG0789@2|Bacteria,1NGZ7@1224|Proteobacteria,1TK9V@1236|Gammaproteobacteria,1X0W7@135613|Chromatiales	135613|Chromatiales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GZD3_k127_4612381_2	768671.ThimaDRAFT_3621	5.04e-45	181.0	COG2304@1|root,COG4295@1|root,COG2304@2|Bacteria,COG4295@2|Bacteria,1R389@1224|Proteobacteria,1T64P@1236|Gammaproteobacteria,1WZ2Y@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF2263,VWA
GZD3_k127_4612381_8	485913.Krac_7008	3.273e-10	73.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889,ko:K17713	-	-	R03136	-	ko00000,ko01000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2,PQQ_3
GZD3_k127_4612381_7	479434.Sthe_0094	6.221e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2G9AH@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_4612381_0	485913.Krac_8783	5.21e-150	484.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
GZD3_k127_4612381_3	1382306.JNIM01000001_gene75	1.238e-35	146.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
GZD3_k127_4612381_1	479435.Kfla_1126	6.199e-59	214.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4612381_4	485913.Krac_12403	1.182e-27	122.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Clp_N,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD3_k127_4612381_9	1906.SFRA_05250	9.181e-06	51.0	2DN6Z@1|root,32VWH@2|Bacteria,2I36E@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3140
GZD3_k127_4623226_3	485913.Krac_9356	6.714e-125	408.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_4623226_1	485913.Krac_9346	2.758e-150	483.0	COG1073@1|root,COG1073@2|Bacteria,2G95Q@200795|Chloroflexi	200795|Chloroflexi	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100
GZD3_k127_4623226_6	485913.Krac_2796	5.617e-14	77.0	COG3860@1|root,COG3860@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20,NUMOD3
GZD3_k127_4623226_4	760568.Desku_1636	2.889e-72	259.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,261SM@186807|Peptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02525,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
GZD3_k127_4623226_2	485913.Krac_9361	2.286e-125	411.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
GZD3_k127_4623226_0	485913.Krac_9360	3.321e-160	512.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
GZD3_k127_4623226_5	1382306.JNIM01000001_gene2428	4.701e-47	171.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD3_k127_4631580_7	1382306.JNIM01000001_gene965	3.793e-77	266.0	COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
GZD3_k127_4631580_2	1382306.JNIM01000001_gene3947	2.563e-128	422.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
GZD3_k127_4631580_12	485913.Krac_11771	2.501e-07	62.0	28SAM@1|root,2ZEMQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4631580_5	485913.Krac_7596	1.787e-118	411.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
GZD3_k127_4631580_3	1382306.JNIM01000001_gene970	1.144e-127	419.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GZD3_k127_4631580_0	1382306.JNIM01000001_gene969	4.31e-142	458.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GZD3_k127_4631580_1	1382306.JNIM01000001_gene3783	3.031e-135	442.0	COG0006@1|root,COG0006@2|Bacteria,2G7X6@200795|Chloroflexi	200795|Chloroflexi	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
GZD3_k127_4631580_11	105420.BBPO01000020_gene5573	1.943e-26	115.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria,2NIVH@228398|Streptacidiphilus	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
GZD3_k127_4631580_8	357808.RoseRS_0178	5.523e-54	218.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_4631580_4	1382306.JNIM01000001_gene1488	1.957e-127	419.0	COG0477@1|root,COG2814@2|Bacteria,2G8XB@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4631580_6	1382306.JNIM01000001_gene2726	8.479e-85	291.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydzE	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_4631580_10	1173024.KI912148_gene2785	8.978e-28	119.0	COG1598@1|root,COG1598@2|Bacteria,1G96V@1117|Cyanobacteria,1JM00@1189|Stigonemataceae	1117|Cyanobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB,HicB_lk_antitox
GZD3_k127_4631580_9	383372.Rcas_0121	6.165e-50	184.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,375AK@32061|Chloroflexia	32061|Chloroflexia	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
GZD3_k127_4636802_4	1448860.BBJO01000030_gene325	0.0001409	46.0	COG1975@1|root,arCOG01929@2157|Archaea,2XVCW@28890|Euryarchaeota,23W02@183963|Halobacteria	183963|Halobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
GZD3_k127_4636802_0	1382306.JNIM01000001_gene3999	2.645e-37	150.0	COG1988@1|root,COG1988@2|Bacteria	2|Bacteria	NT	membrane-bound metal-dependent	ydjM	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0031668,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
GZD3_k127_4636802_1	1382306.JNIM01000001_gene4000	5.573e-29	119.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GZD3_k127_4636802_3	1382306.JNIM01000001_gene3894	8.694e-16	87.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_4638172_0	929506.CbC4_2541	5.425e-198	631.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
GZD3_k127_4638172_1	649831.L083_2335	1.105e-152	503.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DBR5@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4638172_4	196490.AUEZ01000039_gene7044	1.45e-43	165.0	COG3554@1|root,COG3554@2|Bacteria,1RHFQ@1224|Proteobacteria,2U9RI@28211|Alphaproteobacteria,3JU9E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4638172_2	1125971.ASJB01000028_gene7720	2.48e-108	358.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4DXKX@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GZD3_k127_4638172_3	485913.Krac_11878	3.355e-76	262.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_11878|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4647981_2	1382306.JNIM01000001_gene3911	1.765e-65	235.0	COG0466@1|root,COG0466@2|Bacteria,2G7KC@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
GZD3_k127_4647981_0	1382306.JNIM01000001_gene3912	3.882e-225	705.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
GZD3_k127_4647981_1	1382306.JNIM01000001_gene3913	5.908e-111	379.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
GZD3_k127_4650187_1	485913.Krac_1373	1.858e-110	368.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
GZD3_k127_4650187_2	485913.Krac_2841	2.186e-109	370.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4650187_0	485913.Krac_11009	1.457e-223	713.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
GZD3_k127_4650187_5	646529.Desaci_4204	8.046e-11	73.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,261GD@186807|Peptococcaceae	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD3_k127_4650187_3	1382306.JNIM01000001_gene4148	4.856e-83	289.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_465420_1	714943.Mucpa_5296	7.239e-32	126.0	COG3461@1|root,COG3461@2|Bacteria,4NV8V@976|Bacteroidetes,1IYNX@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_465420_0	1382306.JNIM01000001_gene1526	7.495e-86	295.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GZD3_k127_4665962_1	1382306.JNIM01000001_gene733	2.016e-95	331.0	COG5002@1|root,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_4665962_0	1382306.JNIM01000001_gene732	2.296e-119	386.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4670545_5	1214101.BN159_7304	5.08e-26	125.0	COG0457@1|root,COG0457@2|Bacteria,2INUN@201174|Actinobacteria	201174|Actinobacteria	G	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NB-ARC,TPR_10,TPR_12
GZD3_k127_4670545_3	211165.AJLN01000051_gene4966	2.954e-29	119.0	COG1598@1|root,COG1598@2|Bacteria,1G998@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4670545_4	247490.KSU1_C0558	6.265e-27	115.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_4670545_2	485913.Krac_8821	2.063e-42	163.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
GZD3_k127_4670545_1	266117.Rxyl_0283	1.796e-83	285.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
GZD3_k127_4670545_0	1128421.JAGA01000001_gene2146	7.097e-85	303.0	2CA5R@1|root,2Z81H@2|Bacteria,2NRJU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
GZD3_k127_4670545_6	485913.Krac_8762	1.303e-25	107.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_4675276_1	1069080.KB913028_gene999	1.07e-79	274.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H29G@909932|Negativicutes	909932|Negativicutes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
GZD3_k127_4675276_15	368407.Memar_1773	1.639e-14	85.0	COG2968@1|root,arCOG04715@2157|Archaea,2XZAZ@28890|Euryarchaeota,2N9TF@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
GZD3_k127_4675276_5	521098.Aaci_2209	3.29e-49	183.0	COG0494@1|root,COG0494@2|Bacteria,1W5AQ@1239|Firmicutes	1239|Firmicutes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_4675276_14	864567.HMPREF8571_1305	9.713e-15	76.0	COG1051@1|root,COG1051@2|Bacteria,1VCJX@1239|Firmicutes,4HMK8@91061|Bacilli,2TQ73@28037|Streptococcus mitis	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_4675276_11	1382356.JQMP01000003_gene1529	4.41e-32	135.0	COG0546@1|root,COG0546@2|Bacteria,2G9CI@200795|Chloroflexi,27YAX@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
GZD3_k127_4675276_9	485913.Krac_7240	3.793e-33	143.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_4675276_7	1521187.JPIM01000043_gene1923	2.049e-42	161.0	COG0783@1|root,COG0783@2|Bacteria,2G9YH@200795|Chloroflexi,3779J@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
GZD3_k127_4675276_3	479434.Sthe_1547	8.728e-54	192.0	2CMJR@1|root,32U2B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4675276_12	388467.A19Y_1879	6.381e-22	103.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria,1HEWV@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_4675276_6	485913.Krac_5152	1.084e-44	177.0	COG0589@1|root,COG0589@2|Bacteria,2G94S@200795|Chloroflexi	2|Bacteria	T	COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_4675276_10	234267.Acid_2543	1.422e-32	140.0	COG1503@1|root,COG1503@2|Bacteria,3Y6P2@57723|Acidobacteria	57723|Acidobacteria	J	eRF1 domain 3	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach,eRF1_3
GZD3_k127_4675276_18	525904.Tter_2547	4.713e-09	68.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_4675276_0	1278073.MYSTI_05602	2.522e-85	301.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2WTUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
GZD3_k127_4675276_16	479434.Sthe_0641	3.59e-13	71.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
GZD3_k127_4675276_8	485913.Krac_1175	8.727e-35	136.0	COG5002@1|root,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_4680358_2	1476583.DEIPH_ctg033orf0033	4.237e-104	353.0	COG0161@1|root,COG0161@2|Bacteria,1WM0W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
GZD3_k127_4680358_1	526227.Mesil_0745	1.003e-106	353.0	COG0010@1|root,COG0010@2|Bacteria,1WIEY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
GZD3_k127_4680358_0	485913.Krac_10473	5.315e-115	389.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
GZD3_k127_4680358_3	1382306.JNIM01000001_gene1578	2.803e-94	323.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
GZD3_k127_4680358_5	1382306.JNIM01000001_gene3735	3.459e-49	191.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
GZD3_k127_4680358_6	102129.Lepto7375DRAFT_1543	4.329e-49	183.0	COG1309@1|root,COG1309@2|Bacteria,1G61G@1117|Cyanobacteria,1HFKG@1150|Oscillatoriales	1117|Cyanobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
GZD3_k127_4680358_9	326427.Cagg_3353	1.656e-32	132.0	2AKD7@1|root,31B4D@2|Bacteria,2GBQM@200795|Chloroflexi,3762Y@32061|Chloroflexia	32061|Chloroflexia	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
GZD3_k127_4680358_4	1382306.JNIM01000001_gene650	1.166e-69	247.0	COG1947@1|root,COG1947@2|Bacteria,2G71D@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GZD3_k127_4680358_8	926550.CLDAP_39000	8.646e-33	134.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
GZD3_k127_4680358_10	909613.UO65_0663	9.966e-17	92.0	COG0438@1|root,COG2244@1|root,COG0438@2|Bacteria,COG2244@2|Bacteria,2I9DU@201174|Actinobacteria,4E0MA@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_synt
GZD3_k127_4680358_7	485913.Krac_6921	5.209e-37	146.0	COG0613@1|root,COG0613@2|Bacteria,2G71S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GZD3_k127_4681379_1	479434.Sthe_2499	6.366e-73	253.0	29JD5@1|root,306AN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4681379_2	1123368.AUIS01000028_gene1323	5.318e-34	143.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_4681379_0	1123368.AUIS01000028_gene1324	6.499e-200	652.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
GZD3_k127_4681857_1	1382306.JNIM01000001_gene311	3.985e-81	278.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD3_k127_4681857_0	485913.Krac_12200	3.033e-81	279.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	MA20_08830	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GZD3_k127_4681857_2	485913.Krac_3076	4.933e-62	218.0	COG1670@1|root,COG1670@2|Bacteria,2G76C@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GZD3_k127_4682775_3	485913.Krac_3078	1.038e-35	139.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD3_k127_4682775_0	485913.Krac_3079	4.238e-213	674.0	COG0747@1|root,COG0747@2|Bacteria,2G6BC@200795|Chloroflexi	200795|Chloroflexi	E	COGs COG0747 ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_4682775_1	1121946.AUAX01000007_gene2865	3.412e-39	158.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4DC18@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GZD3_k127_4682775_2	1121033.AUCF01000031_gene72	2.091e-36	143.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,2JRXU@204441|Rhodospirillales	204441|Rhodospirillales	S	CoA binding domain	yccU	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
GZD3_k127_4682775_4	36809.MAB_3231	4.805e-27	117.0	COG2050@1|root,COG2050@2|Bacteria,2GV7U@201174|Actinobacteria,23BQU@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
GZD3_k127_4687095_5	326427.Cagg_0094	1.824e-10	64.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,375V0@32061|Chloroflexia	32061|Chloroflexia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GZD3_k127_4687095_1	485913.Krac_12275	1.794e-40	166.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
GZD3_k127_4687095_0	525904.Tter_1659	5.184e-88	304.0	COG0006@1|root,COG0006@2|Bacteria,2NP41@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
GZD3_k127_4687095_4	485913.Krac_1779	1.013e-12	78.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD3_k127_4687095_3	485913.Krac_0029	3.793e-33	143.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_4687095_2	1120956.JHZK01000022_gene1568	1.965e-35	150.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
GZD3_k127_4687095_6	1382306.JNIM01000001_gene719	5.569e-10	61.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
GZD3_k127_4696200_5	316274.Haur_1995	3.936e-34	146.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
GZD3_k127_4696200_2	926550.CLDAP_21020	3.973e-56	205.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_4696200_6	485913.Krac_3481	1.964e-09	62.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9
GZD3_k127_4696200_3	1382306.JNIM01000001_gene750	1.534e-46	176.0	COG1302@1|root,COG1302@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GZD3_k127_4696200_8	767817.Desgi_2612	3.533e-08	63.0	COG1302@1|root,COG1302@2|Bacteria,1VF8P@1239|Firmicutes,24R1D@186801|Clostridia,2632Y@186807|Peptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
GZD3_k127_4696200_0	211114.JOEF01000006_gene2561	7.145e-261	819.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4DX52@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
GZD3_k127_4696200_1	1380347.JNII01000005_gene2977	3.137e-179	574.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_4696200_4	1121946.AUAX01000010_gene3762	6.82e-36	144.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DBNX@85008|Micromonosporales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.8	ko:K01537,ko:K12953	-	-	-	-	ko00000,ko01000	3.A.3,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GZD3_k127_4704379_2	479434.Sthe_0384	1.387e-48	178.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi,27XWQ@189775|Thermomicrobia	189775|Thermomicrobia	M	Mannose-6-phosphate isomerase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
GZD3_k127_4704379_1	1382306.JNIM01000001_gene900	3.479e-58	210.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD3_k127_4704379_3	485913.Krac_1964	2.277e-48	179.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_4704379_0	485913.Krac_12597	8.703e-89	298.0	COG0477@1|root,COG2814@2|Bacteria,2G5SP@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
GZD3_k127_4704976_1	1382306.JNIM01000001_gene1491	3.388e-32	128.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_4704976_2	1124780.ANNU01000028_gene946	2.788e-26	120.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
GZD3_k127_4704976_0	485913.Krac_6660	2.423e-84	311.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,GSDH,SGL
GZD3_k127_4704976_4	398767.Glov_2339	0.0009364	53.0	COG1361@1|root,COG3055@1|root,COG4409@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG4409@2|Bacteria,COG4932@2|Bacteria,1R5HW@1224|Proteobacteria,42R1Y@68525|delta/epsilon subdivisions,2WMXD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
GZD3_k127_4704976_3	290399.Arth_2496	4.962e-06	60.0	COG1749@1|root,COG1749@2|Bacteria,2I2X3@201174|Actinobacteria	201174|Actinobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
GZD3_k127_4706519_9	1382306.JNIM01000001_gene3902	2.71e-31	130.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4706519_8	485913.Krac_12549	5.005e-32	136.0	COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GZD3_k127_4706519_6	1382306.JNIM01000001_gene3900	4.278e-72	256.0	COG1235@1|root,COG1235@2|Bacteria,2G833@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GZD3_k127_4706519_7	485913.Krac_5447	2.426e-67	236.0	COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Transcription regulator, AsnC-type-like	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
GZD3_k127_4706519_1	485913.Krac_5448	5.456e-120	393.0	COG5006@1|root,COG5006@2|Bacteria	2|Bacteria	S	threonine efflux transmembrane transporter activity	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
GZD3_k127_4706519_4	1540257.JQMW01000012_gene2642	1.133e-92	311.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,2482S@186801|Clostridia,36GH9@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
GZD3_k127_4706519_11	1174528.JH992888_gene235	0.0002089	49.0	2FBC6@1|root,343I1@2|Bacteria,1GFR1@1117|Cyanobacteria,1JM7B@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4706519_10	1122927.KB895413_gene1464	1.353e-13	78.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,26S8H@186822|Paenibacillaceae	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_4706519_3	383372.Rcas_3189	1.631e-98	330.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
GZD3_k127_4706519_5	1382306.JNIM01000001_gene3719	3.715e-76	265.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD3_k127_4706519_0	1382306.JNIM01000001_gene280	4.11e-187	599.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K01176,ko:K07405	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13,GH57	-	Glyco_hydro_57
GZD3_k127_4706519_2	485913.Krac_12226	1.773e-112	368.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	iSDY_1059.SDY_4061	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_4723659_0	653045.Strvi_0506	4.355e-28	122.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
GZD3_k127_4723659_3	1169154.KB897784_gene4059	0.0002961	52.0	COG0454@1|root,COG0456@2|Bacteria,2GMXI@201174|Actinobacteria	201174|Actinobacteria	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
GZD3_k127_4723659_2	994479.GL877878_gene3496	4.596e-11	69.0	COG1943@1|root,COG1943@2|Bacteria,2IGK0@201174|Actinobacteria,4EF23@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD3_k127_4723659_1	656024.FsymDg_0829	5.687e-18	96.0	COG3420@1|root,COG3420@2|Bacteria,2GPK6@201174|Actinobacteria	201174|Actinobacteria	P	TIR domain	-	-	-	ko:K10297	-	-	-	-	ko00000,ko04121	-	-	-	Beta_helix,TIR_2
GZD3_k127_4730727_1	485913.Krac_8884	4.766e-184	588.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
GZD3_k127_4730727_8	485913.Krac_9884	6.473e-19	88.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213,ko:K08364	ko04978,map04978	-	-	-	ko00000,ko00001,ko02000	1.A.72.1	-	-	HMA
GZD3_k127_4730727_9	211165.AJLN01000055_gene4563	5.274e-14	78.0	COG4113@1|root,COG4113@2|Bacteria,1G8AN@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_4730727_3	1382306.JNIM01000001_gene1485	5.77e-110	369.0	COG2807@1|root,COG2807@2|Bacteria,2G7JA@200795|Chloroflexi	200795|Chloroflexi	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
GZD3_k127_4730727_4	1382306.JNIM01000001_gene1275	1.28e-101	358.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_4730727_5	1382306.JNIM01000001_gene3737	9.368e-57	206.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
GZD3_k127_4730727_2	485913.Krac_9113	4.472e-129	424.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
GZD3_k127_4730727_10	1249634.D781_0605	1.104e-06	61.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,400TX@613|Serratia	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
GZD3_k127_4730727_7	319003.Bra1253DRAFT_00419	3.758e-30	132.0	28SWP@1|root,2ZF66@2|Bacteria,1PAGU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4730727_0	485913.Krac_6820	1.708e-244	758.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
GZD3_k127_4753620_0	485913.Krac_7849	2.45e-105	357.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_4753620_2	1382306.JNIM01000001_gene1979	6.493e-37	161.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
GZD3_k127_4753620_3	1382306.JNIM01000001_gene1980	8.364e-23	101.0	COG2018@1|root,COG2018@2|Bacteria,2G9R6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
GZD3_k127_4753620_1	1382306.JNIM01000001_gene1981	5.016e-52	186.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
GZD3_k127_4756837_2	485913.Krac_5261	3.893e-89	303.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	rhaR	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
GZD3_k127_4756837_3	485913.Krac_5262	9.761e-61	219.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
GZD3_k127_4756837_5	316274.Haur_0093	8.157e-17	86.0	COG4392@1|root,COG4392@2|Bacteria,2G7HT@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
GZD3_k127_4756837_1	368408.Tpen_0832	2.757e-93	316.0	COG0330@1|root,arCOG01915@2157|Archaea,2XPQN@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
GZD3_k127_4756837_4	1089553.Tph_c03970	7.235e-35	142.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia,42F1N@68295|Thermoanaerobacterales	186801|Clostridia	O	Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
GZD3_k127_4756837_0	1382306.JNIM01000001_gene1970	1.222e-98	329.0	COG0644@1|root,COG0644@2|Bacteria,2G7FR@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,FAD_oxidored,HI0933_like
GZD3_k127_4799923_0	485913.Krac_7802	6.756e-99	336.0	COG4745@1|root,COG4745@2|Bacteria,2G6HI@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_4799923_1	1382306.JNIM01000001_gene376	3.839e-68	241.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	-	-	-	-	-	-	-	-	-	-	-	-	Ribonucleas_3_3,dsrm
GZD3_k127_4803089_6	1089553.Tph_c04850	3.978e-26	113.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
GZD3_k127_4803089_5	404589.Anae109_4284	8.755e-27	119.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD3_k127_4803089_4	926569.ANT_22580	1.472e-49	198.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GZD3_k127_4803089_3	1382306.JNIM01000001_gene3650	1.658e-62	224.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	1.3.1.34,3.1.2.6	ko:K00219,ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Lactamase_B,Rhodanese
GZD3_k127_4803089_2	1382306.JNIM01000001_gene3649	4.843e-86	293.0	COG0491@1|root,COG0491@2|Bacteria,2G8W8@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_4803089_0	981369.JQMJ01000004_gene4054	5.187e-162	529.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria,2NKAJ@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4803089_1	765420.OSCT_1014	7.039e-136	439.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi,376EH@32061|Chloroflexia	32061|Chloroflexia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
GZD3_k127_4826425_2	1382306.JNIM01000001_gene2738	1.318e-162	521.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_4826425_3	485913.Krac_11245	1.102e-141	462.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
GZD3_k127_4826425_11	927677.ALVU02000001_gene4090	9.206e-13	75.0	COG4113@1|root,COG4113@2|Bacteria,1G6BG@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
GZD3_k127_4826425_10	1382306.JNIM01000001_gene2753	4.548e-29	128.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
GZD3_k127_4826425_0	1120949.KB903316_gene63	2.864e-216	707.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DH9I@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
GZD3_k127_4826425_9	234267.Acid_3612	1.057e-34	148.0	2E3HM@1|root,32W74@2|Bacteria,3Y85J@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4826425_1	1211815.CBYP010000015_gene2652	1.476e-166	532.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EU5M@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_4826425_8	1120956.JHZK01000022_gene1568	1.652e-36	151.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
GZD3_k127_4826425_6	266117.Rxyl_2819	1.651e-45	177.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
GZD3_k127_4826425_4	1463926.JOCA01000002_gene5637	3.31e-85	287.0	COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
GZD3_k127_4826425_5	485913.Krac_11704	4.625e-66	237.0	COG1985@1|root,COG1985@2|Bacteria,2G97Y@200795|Chloroflexi	200795|Chloroflexi	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_4837194_5	1382306.JNIM01000001_gene693	6.303e-80	273.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
GZD3_k127_4837194_1	1382306.JNIM01000001_gene692	3.003e-168	548.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
GZD3_k127_4837194_7	485913.Krac_10277	3.436e-44	164.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
GZD3_k127_4837194_3	1382306.JNIM01000001_gene894	1.666e-140	459.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_4837194_2	1382306.JNIM01000001_gene895	2.518e-152	497.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
GZD3_k127_4837194_4	1382306.JNIM01000001_gene896	3.997e-88	308.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_4837194_6	1118060.CAGZ01000026_gene768	4.018e-59	217.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CVFS@84998|Coriobacteriia	84998|Coriobacteriia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GZD3_k127_4837194_0	1382306.JNIM01000001_gene909	2.618e-171	562.0	COG0322@1|root,COG0322@2|Bacteria,2G7WZ@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
GZD3_k127_4837194_8	1173028.ANKO01000112_gene4812	6.002e-25	109.0	COG1598@1|root,COG1598@2|Bacteria,1G8YA@1117|Cyanobacteria,1HD7Z@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4837194_9	368407.Memar_0546	1.673e-10	63.0	COG1724@1|root,arCOG03088@2157|Archaea	2157|Archaea	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_4860585_6	33876.JNXY01000021_gene4782	4.498e-36	144.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_4860585_1	326427.Cagg_1299	3.054e-71	247.0	COG0807@1|root,COG0807@2|Bacteria	2|Bacteria	H	GTP cyclohydrolase II activity	ribBA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
GZD3_k127_4860585_0	485913.Krac_8646	1.335e-114	389.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD3_k127_4860585_4	1173025.GEI7407_3302	1.359e-49	188.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
GZD3_k127_4860585_5	1382306.JNIM01000001_gene1408	1.081e-37	152.0	COG1796@1|root,COG1796@2|Bacteria,2G97J@200795|Chloroflexi	200795|Chloroflexi	L	Helix-hairpin-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
GZD3_k127_4860585_2	1382306.JNIM01000001_gene527	1.44e-70	253.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
GZD3_k127_4860585_3	479434.Sthe_3324	3.444e-70	243.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000,ko01001	-	-	iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Isochorismatase
GZD3_k127_4860585_8	1122609.AUGT01000012_gene4416	0.0002462	50.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4860585_7	525904.Tter_1056	2.138e-11	66.0	COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S21	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
GZD3_k127_4861655_3	1380370.JIBA01000015_gene301	5.4e-14	76.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_4861655_0	1089544.KB912942_gene214	9.158e-41	156.0	2DSM3@1|root,33GM1@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD3_k127_4861655_1	2074.JNYD01000006_gene1631	7.044e-29	123.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4E3RM@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_4861655_2	1172188.KB911824_gene3347	3.964e-20	93.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria,4FK1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
GZD3_k127_4861655_4	930171.Asphe3_23900	2.815e-06	57.0	arCOG08955@1|root,2ZN6H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_48750_1	1382306.JNIM01000001_gene1327	2.303e-195	621.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
GZD3_k127_48750_2	1382306.JNIM01000001_gene1328	2.531e-179	576.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
GZD3_k127_48750_12	381666.H16_B2006	0.0004736	48.0	COG1487@1|root,COG1487@2|Bacteria,1N0W5@1224|Proteobacteria,2WGAU@28216|Betaproteobacteria,1KG2Q@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
GZD3_k127_48750_9	485913.Krac_2894	1.052e-11	66.0	293YG@1|root,2ZRDH@2|Bacteria	2|Bacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD3_k127_48750_8	661478.OP10G_3856	2.833e-19	102.0	293YG@1|root,2ZRDH@2|Bacteria	2|Bacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD3_k127_48750_13	420324.KI912082_gene6961	0.0004839	52.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1R6IK@1224|Proteobacteria,2U45Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TIR_2,TPR_19,TolB_N
GZD3_k127_48750_6	264732.Moth_1333	1.401e-62	226.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
GZD3_k127_48750_11	1429046.RR21198_0070	5.899e-05	51.0	2ENMM@1|root,33G8Y@2|Bacteria,2H5W8@201174|Actinobacteria,4G3EM@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_48750_0	485913.Krac_7787	2.228e-267	839.0	COG1154@1|root,COG1154@2|Bacteria,2G68R@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
GZD3_k127_48750_7	485913.Krac_9136	3.926e-62	223.0	COG2206@1|root,COG2206@2|Bacteria,2GBKK@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
GZD3_k127_48750_4	105422.BBPM01000005_gene6179	4.613e-78	276.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GZD3_k127_48750_3	1382306.JNIM01000001_gene4186	5.011e-117	387.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
GZD3_k127_48750_5	485913.Krac_8719	3.33e-72	267.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
GZD3_k127_48750_10	479434.Sthe_3136	3.548e-09	69.0	2DP6G@1|root,330R3@2|Bacteria,2G93U@200795|Chloroflexi,27YFD@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
GZD3_k127_4900843_1	1449063.JMLS01000024_gene3695	6.049e-29	122.0	COG0454@1|root,COG0456@2|Bacteria,1V1NC@1239|Firmicutes,4ISA1@91061|Bacilli,26ZH1@186822|Paenibacillaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
GZD3_k127_4900843_0	485913.Krac_7559	1.617e-136	450.0	COG0473@1|root,COG0473@2|Bacteria,2G63C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GZD3_k127_4901254_0	926550.CLDAP_08900	9.136e-95	326.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
GZD3_k127_4901254_1	383372.Rcas_1098	2.498e-51	188.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi,374SI@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
GZD3_k127_4907575_0	710685.MycrhN_2833	2.534e-121	404.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,2387G@1762|Mycobacteriaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
GZD3_k127_4907575_1	309801.trd_0948	1.817e-11	71.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_4927211_1	1157490.EL26_23430	4.046e-91	307.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli,279I1@186823|Alicyclobacillaceae	91061|Bacilli	F	Amidohydrolase family	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
GZD3_k127_4927211_0	485913.Krac_11396	2.099e-122	404.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_4927211_2	591158.SSMG_05238	1.568e-11	64.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
GZD3_k127_4950832_3	1382306.JNIM01000001_gene2717	7.003e-90	301.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
GZD3_k127_4950832_6	1499967.BAYZ01000026_gene1636	6.097e-29	118.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GZD3_k127_4950832_4	485913.Krac_10414	1.189e-60	240.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
GZD3_k127_4950832_2	1382306.JNIM01000001_gene3781	4.112e-109	362.0	COG2159@1|root,COG2159@2|Bacteria,2G6CW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
GZD3_k127_4950832_0	1382306.JNIM01000001_gene4111	7.624e-133	430.0	COG0761@1|root,COG0761@2|Bacteria,2G75Z@200795|Chloroflexi	200795|Chloroflexi	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
GZD3_k127_4950832_7	1223523.H340_14351	8.156e-08	66.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
GZD3_k127_4950832_1	1382306.JNIM01000001_gene1342	9.832e-120	401.0	COG0337@1|root,COG0337@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
GZD3_k127_4956843_0	1382315.JPOI01000001_gene891	2.711e-100	340.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,1WEN2@129337|Geobacillus	91061|Bacilli	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
GZD3_k127_4956843_1	485913.Krac_7857	1.273e-35	141.0	COG2306@1|root,COG2306@2|Bacteria,2GBPB@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
GZD3_k127_4965547_0	1068980.ARVW01000001_gene6276	1.993e-27	129.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria,4E0XU@85010|Pseudonocardiales	201174|Actinobacteria	S	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
GZD3_k127_4968257_2	1382306.JNIM01000001_gene2516	1.555e-82	282.0	COG1045@1|root,COG1045@2|Bacteria,2G6DI@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
GZD3_k127_4968257_1	1382306.JNIM01000001_gene736	6.103e-181	593.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G83U@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
GZD3_k127_4968257_0	1382306.JNIM01000001_gene736	5.711e-257	816.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G83U@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
GZD3_k127_4968257_4	1254432.SCE1572_31450	3.008e-36	149.0	COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,43B68@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	KDPG and KHG aldolase	dgoA	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008674,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.1.2.14,4.1.2.21,4.1.3.42	ko:K01625,ko:K01631	ko00030,ko00052,ko00630,ko01100,ko01120,ko01200,map00030,map00052,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00552,M00631	R00470,R01064,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
GZD3_k127_4980411_1	1382306.JNIM01000001_gene3732	3.386e-50	203.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD3_k127_4980411_0	1382306.JNIM01000001_gene3731	5.768e-197	658.0	COG0577@1|root,COG0577@2|Bacteria,2G6CK@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_4986452_0	485913.Krac_2374	1.743e-64	237.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
GZD3_k127_4986452_2	35754.JNYJ01000012_gene926	2.29e-37	149.0	COG2074@1|root,COG2074@2|Bacteria,2GMUY@201174|Actinobacteria,4DCXP@85008|Micromonosporales	201174|Actinobacteria	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,SKI
GZD3_k127_4986452_1	485913.Krac_11748	4.495e-46	170.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
GZD3_k127_4996507_0	485913.Krac_8498	1.087e-34	139.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
GZD3_k127_4996507_3	1461580.CCAS010000008_gene1140	0.0001601	48.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1ZJ1K@1386|Bacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
GZD3_k127_4996507_1	760192.Halhy_0057	4.455e-28	116.0	2FCGD@1|root,344JU@2|Bacteria,4P6KV@976|Bacteroidetes,1IZ55@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_501186_0	1173024.KI912150_gene1307	4.142e-53	199.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
GZD3_k127_501186_2	485913.Krac_6774	1.11e-06	51.0	COG1670@1|root,COG1670@2|Bacteria,2G76C@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
GZD3_k127_501186_1	525904.Tter_2586	1.468e-08	60.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
GZD3_k127_501730_2	1382306.JNIM01000001_gene410	3.173e-29	121.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_501730_1	1869.MB27_12150	3.343e-36	153.0	COG5542@1|root,COG5542@2|Bacteria,2HWIG@201174|Actinobacteria,4DIWB@85008|Micromonosporales	201174|Actinobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
GZD3_k127_501730_3	1128421.JAGA01000002_gene308	6.013e-22	111.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
GZD3_k127_501730_0	485913.Krac_8789	1.47e-124	408.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
GZD3_k127_5043922_3	756067.MicvaDRAFT_1008	3.578e-78	270.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
GZD3_k127_5043922_5	485913.Krac_8872	7.605e-64	222.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi	200795|Chloroflexi	FG	Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT,NUDIX
GZD3_k127_5043922_8	1382306.JNIM01000001_gene3945	5.294e-35	149.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene3945|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5043922_6	1382306.JNIM01000001_gene3944	1.44e-44	175.0	COG1940@1|root,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
GZD3_k127_5043922_7	1382306.JNIM01000001_gene3980	4.105e-40	162.0	COG1184@1|root,COG1184@2|Bacteria,2G9CC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the eIF-2B alpha beta delta subunits family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
GZD3_k127_5043922_9	1382306.JNIM01000001_gene3499	6.173e-33	133.0	COG1051@1|root,COG1051@2|Bacteria,2GA98@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_5043922_1	383372.Rcas_4271	8.223e-94	320.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_5043922_0	1382306.JNIM01000001_gene4189	1.813e-282	881.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi	200795|Chloroflexi	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5043922_12	643473.KB235930_gene1791	2.555e-20	95.0	COG2127@1|root,COG2127@2|Bacteria,1G6M6@1117|Cyanobacteria,1HP08@1161|Nostocales	1117|Cyanobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
GZD3_k127_5043922_4	485913.Krac_1340	4.065e-69	242.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
GZD3_k127_5043922_10	656024.FsymDg_2380	4.819e-31	130.0	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria,4EVRR@85013|Frankiales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
GZD3_k127_5043922_2	1382306.JNIM01000001_gene2443	1.243e-87	298.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
GZD3_k127_5043922_11	1173026.Glo7428_2619	1.022e-21	97.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5043922_17	1356852.N008_17695	1.148e-05	48.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,47N3N@768503|Cytophagia	976|Bacteroidetes	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
GZD3_k127_5053212_2	1169144.KB911000_gene1601	2.942e-12	76.0	COG2271@1|root,COG2271@2|Bacteria,1V0VC@1239|Firmicutes,4HC5B@91061|Bacilli,1ZD8A@1386|Bacillus	91061|Bacilli	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_5053212_1	272563.CD630_35650	1.952e-25	117.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,25QQ7@186804|Peptostreptococcaceae	186801|Clostridia	K	FCD	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD3_k127_5053212_0	675635.Psed_4153	5.125e-37	144.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
GZD3_k127_5055810_4	485913.Krac_11308	5.548e-06	51.0	2APF0@1|root,31EHN@2|Bacteria,2G7DI@200795|Chloroflexi	200795|Chloroflexi	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
GZD3_k127_5055810_0	1382306.JNIM01000001_gene2872	2.84e-147	477.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
GZD3_k127_5055810_1	1382306.JNIM01000001_gene2873	2.295e-115	399.0	COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_5055810_2	1382306.JNIM01000001_gene2874	7.019e-102	346.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_5055810_3	1382306.JNIM01000001_gene2875	1.626e-62	218.0	COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
GZD3_k127_5056901_1	485913.Krac_11273	7.202e-62	216.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
GZD3_k127_5056901_0	485913.Krac_7843	7.157e-78	264.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
GZD3_k127_5060425_0	926560.KE387023_gene2253	8.529e-172	544.0	COG0119@1|root,COG0119@2|Bacteria,1WKXK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
GZD3_k127_5060425_1	46234.ANA_C10116	5.155e-05	48.0	COG2442@1|root,COG2442@2|Bacteria,1GI6W@1117|Cyanobacteria,1HT4G@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_5104745_1	479432.Sros_5479	2.239e-94	314.0	COG1357@1|root,COG1357@2|Bacteria,2GM3W@201174|Actinobacteria,4EGQP@85012|Streptosporangiales	201174|Actinobacteria	S	Pentapeptide repeats (8 copies)	yybG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
GZD3_k127_5104745_0	1382306.JNIM01000001_gene1047	4.311e-104	343.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
GZD3_k127_5122666_4	935863.AWZR01000004_gene684	4.947e-10	70.0	2F54Q@1|root,33XRS@2|Bacteria,1NVNV@1224|Proteobacteria,1T6V8@1236|Gammaproteobacteria,1X884@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
GZD3_k127_5122666_1	485913.Krac_12103	2.182e-61	233.0	COG0768@1|root,COG0768@2|Bacteria,2G7V1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
GZD3_k127_5122666_0	1150626.PHAMO_230029	2.495e-95	323.0	COG1533@1|root,COG1533@2|Bacteria,1Q22I@1224|Proteobacteria,2U40R@28211|Alphaproteobacteria,2JQCI@204441|Rhodospirillales	204441|Rhodospirillales	L	Domain of unknown function (DUF1848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
GZD3_k127_5122666_2	395961.Cyan7425_1333	1.823e-28	119.0	COG4634@1|root,COG4634@2|Bacteria,1G720@1117|Cyanobacteria,3KJ3X@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5122666_3	28072.Nos7524_1617	2.91e-26	113.0	COG2442@1|root,COG2442@2|Bacteria,1G8U9@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_5123773_2	1137271.AZUM01000010_gene1770	1.714e-06	59.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4DZ71@85010|Pseudonocardiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
GZD3_k127_5123773_1	485913.Krac_8550	8.674e-84	287.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
GZD3_k127_5123773_0	485913.Krac_4332	2.407e-163	541.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G7SH@200795|Chloroflexi	2|Bacteria	EU	SPTR D1C8R1 Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GZD3_k127_5136880_3	326427.Cagg_0248	4.529e-05	55.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD3_k127_5136880_0	319225.Plut_0242	5.195e-47	188.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
GZD3_k127_5136880_2	1378168.N510_00393	2.192e-05	52.0	COG5573@1|root,COG5573@2|Bacteria,1UIAH@1239|Firmicutes	1239|Firmicutes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
GZD3_k127_5136880_1	485913.Krac_2194	3.702e-21	93.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
GZD3_k127_5161840_4	1353528.DT23_15335	7.89e-08	55.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2XKUP@285107|Thioclava	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	oppD	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
GZD3_k127_5161840_2	485913.Krac_11336	2.992e-96	324.0	COG1173@1|root,COG1173@2|Bacteria,2G63I@200795|Chloroflexi	200795|Chloroflexi	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
GZD3_k127_5161840_3	1121377.KB906409_gene866	9.038e-84	291.0	COG0601@1|root,COG0601@2|Bacteria,1WIUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
GZD3_k127_5161840_1	485913.Krac_3713	7.691e-112	382.0	COG0747@1|root,COG0747@2|Bacteria,2G6MN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_5161840_0	1382306.JNIM01000001_gene1890	1.708e-174	559.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
GZD3_k127_5200595_3	243159.AFE_0393	1.337e-67	236.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,2NCPG@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
GZD3_k127_5200595_0	485913.Krac_5313	6.768e-217	685.0	COG2072@1|root,COG2072@2|Bacteria,2G7W0@200795|Chloroflexi	2|Bacteria	C	PFAM FAD dependent oxidoreductase	hapE_1	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0055114	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3
GZD3_k127_5200595_2	937777.Deipe_1201	1.745e-85	291.0	COG2021@1|root,COG2021@2|Bacteria,1WNIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_5200595_4	1450694.BTS2_1309	2.367e-17	85.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,1ZDF2@1386|Bacillus	91061|Bacilli	E	Peptidase dimerisation domain	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_5200595_1	926550.CLDAP_18980	4.136e-203	642.0	COG2195@1|root,COG2195@2|Bacteria,2G7H0@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
GZD3_k127_52526_0	316274.Haur_4945	3.486e-58	207.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
GZD3_k127_52526_2	319225.Plut_0917	0.0002844	47.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
GZD3_k127_52526_1	1172181.KB911703_gene211	5.48e-39	152.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GZD3_k127_5259569_5	47763.JNZA01000017_gene1409	2.746e-91	305.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
GZD3_k127_5259569_6	1123248.KB893326_gene1345	2.401e-42	171.0	COG0451@1|root,COG0451@2|Bacteria,4NN4T@976|Bacteroidetes	976|Bacteroidetes	GM	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
GZD3_k127_5259569_2	1128421.JAGA01000002_gene1203	1.998e-116	384.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_5259569_1	485913.Krac_5142	1.515e-150	491.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
GZD3_k127_5259569_3	1382306.JNIM01000001_gene1165	1.144e-114	389.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
GZD3_k127_5259569_4	485913.Krac_11113	2.784e-107	360.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
GZD3_k127_5259569_7	1120956.JHZK01000041_gene3073	1.024e-11	75.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_5259569_0	1382306.JNIM01000001_gene1168	1.618e-188	595.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
GZD3_k127_5274863_1	344747.PM8797T_12568	3.116e-66	230.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
GZD3_k127_5274863_0	485913.Krac_1269	5.883e-86	295.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD3_k127_5274863_2	485913.Krac_1268	2.116e-40	156.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
GZD3_k127_5304159_3	469371.Tbis_1015	1.212e-58	208.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4E53R@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD3_k127_5304159_2	1123023.JIAI01000001_gene6028	4.623e-81	273.0	COG3871@1|root,COG3871@2|Bacteria,2I3KD@201174|Actinobacteria,4E3CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD3_k127_5304159_4	1894.JOER01000023_gene7295	1.493e-58	205.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_5304159_1	1382306.JNIM01000001_gene2426	2.41e-123	410.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD3_k127_5304159_0	1382306.JNIM01000001_gene2427	2.973e-157	498.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
GZD3_k127_5321606_0	1382356.JQMP01000003_gene2310	3.614e-127	419.0	COG1804@1|root,COG1804@2|Bacteria,2GBSM@200795|Chloroflexi,27Z2E@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.20	ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
GZD3_k127_5321606_1	1121877.JQKF01000020_gene2502	2.633e-104	353.0	COG0683@1|root,COG0683@2|Bacteria,2HGK2@201174|Actinobacteria,4CNIP@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_5321606_2	525909.Afer_0504	9.248e-43	160.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_5322033_1	399550.Smar_1545	2.48e-13	75.0	COG4818@1|root,arCOG04344@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
GZD3_k127_5322033_0	479434.Sthe_1359	2.225e-85	300.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
GZD3_k127_5326000_1	1242864.D187_002979	7.206e-12	79.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,43BZS@68525|delta/epsilon subdivisions,2X7AJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
GZD3_k127_5326000_0	1382306.JNIM01000001_gene17	4.304e-46	176.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023	2.2.1.2	ko:K00616,ko:K08313,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501	TAL_FSA
GZD3_k127_5326000_2	1121087.AUCK01000014_gene320	1.175e-06	55.0	COG3296@1|root,COG3296@2|Bacteria,1VJNI@1239|Firmicutes,4HPKT@91061|Bacilli,1ZIB8@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
GZD3_k127_5330996_1	485913.Krac_8765	1.346e-79	271.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
GZD3_k127_5330996_3	459495.SPLC1_S051120	5.593e-23	100.0	2E46S@1|root,32Z2Q@2|Bacteria,1G73R@1117|Cyanobacteria,1HBIU@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5330996_0	1174528.JH992888_gene211	7.15e-162	515.0	COG4804@1|root,COG4804@2|Bacteria,1G1QU@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
GZD3_k127_5330996_2	99598.Cal7507_0938	3.335e-39	148.0	COG1479@1|root,COG1479@2|Bacteria,1G3HZ@1117|Cyanobacteria,1HKKS@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
GZD3_k127_5331698_7	1278073.MYSTI_02364	3.116e-07	53.0	COG1550@1|root,COG1550@2|Bacteria,1NBXZ@1224|Proteobacteria,42W9E@68525|delta/epsilon subdivisions,2WRK0@28221|Deltaproteobacteria,2YW04@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
GZD3_k127_5331698_6	269084.syc0522_d	9.36e-10	70.0	COG0697@1|root,COG0697@2|Bacteria,1G08M@1117|Cyanobacteria,1H3JG@1129|Synechococcus	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_5331698_4	1403819.BATR01000164_gene5534	1.108e-57	205.0	COG5113@1|root,COG3236@2|Bacteria,46XQP@74201|Verrucomicrobia,2IWDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768
GZD3_k127_5331698_0	485913.Krac_11648	5.408e-170	586.0	28KV5@1|root,2ZABS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
GZD3_k127_5331698_2	1382306.JNIM01000001_gene108	1.965e-92	320.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
GZD3_k127_5331698_5	485913.Krac_0435	8.084e-27	111.0	COG0457@1|root,COG0457@2|Bacteria	485913.Krac_0435|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5331698_3	1382306.JNIM01000001_gene3940	3.234e-74	262.0	COG0491@1|root,COG0491@2|Bacteria,2G7QF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_5344157_1	485913.Krac_12533	9.565e-68	235.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
GZD3_k127_5344157_0	485913.Krac_12534	0.0	1110.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
GZD3_k127_5346284_18	696281.Desru_3186	1.428e-39	155.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,24G83@186801|Clostridia,2658Y@186807|Peptococcaceae	186801|Clostridia	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31,Ubie_methyltran
GZD3_k127_5346284_22	1907.SGLAU_33060	1.653e-22	102.0	2EF5E@1|root,31KM2@2|Bacteria,2IKZ8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5346284_3	1382306.JNIM01000001_gene83	6.814e-146	477.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
GZD3_k127_5346284_11	485913.Krac_7202	4.459e-95	327.0	COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi	2|Bacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_5346284_5	1382306.JNIM01000001_gene3995	1.021e-140	453.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
GZD3_k127_5346284_2	485913.Krac_1474	9.598e-150	477.0	COG1131@1|root,COG1131@2|Bacteria,2G6E6@200795|Chloroflexi	2|Bacteria	P	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_5346284_10	485913.Krac_0776	9.145e-104	351.0	2EG3C@1|root,339VC@2|Bacteria,2G9S3@200795|Chloroflexi	200795|Chloroflexi	S	sptr d1c5w1	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5346284_12	485913.Krac_0777	3.962e-85	285.0	COG1595@1|root,COG1595@2|Bacteria,2G9DR@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_5346284_15	485913.Krac_12358	4.677e-58	209.0	COG1666@1|root,COG1666@2|Bacteria,2G6TD@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
GZD3_k127_5346284_19	485913.Krac_8693	4.598e-37	160.0	COG0596@1|root,COG0596@2|Bacteria,2G7BF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_5346284_14	1382306.JNIM01000001_gene3921	9.411e-69	240.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
GZD3_k127_5346284_20	1366050.N234_26515	1.188e-32	141.0	COG1752@1|root,COG1752@2|Bacteria,1MX8Y@1224|Proteobacteria,2VKNF@28216|Betaproteobacteria,1K0PA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
GZD3_k127_5346284_8	1382306.JNIM01000001_gene2725	2.112e-108	364.0	COG0730@1|root,COG4272@1|root,COG0730@2|Bacteria,COG4272@2|Bacteria,2G6ZH@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	DUF1634,TauE
GZD3_k127_5346284_27	1382359.JIAL01000001_gene2953	3.419e-07	61.0	COG4272@1|root,COG4272@2|Bacteria,3Y5P5@57723|Acidobacteria,2JJWD@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
GZD3_k127_5346284_6	1183438.GKIL_3693	8.216e-119	394.0	COG3569@1|root,COG3569@2|Bacteria,1G2R6@1117|Cyanobacteria	1117|Cyanobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
GZD3_k127_5346284_1	485913.Krac_3434	1.152e-153	497.0	COG4447@1|root,COG4447@2|Bacteria,2G5ZD@200795|Chloroflexi	200795|Chloroflexi	S	BNR/Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GZD3_k127_5346284_28	1040989.AWZU01000025_gene6305	6.165e-06	53.0	COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
GZD3_k127_5346284_21	485913.Krac_3435	1.503e-25	112.0	COG1977@1|root,COG1977@2|Bacteria,2G74G@200795|Chloroflexi	2|Bacteria	H	PFAM thiamineS protein	cysO	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
GZD3_k127_5346284_7	485913.Krac_8290	1.196e-109	366.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
GZD3_k127_5346284_13	1382306.JNIM01000001_gene1350	4.141e-70	244.0	COG0110@1|root,COG0110@2|Bacteria,2G7B9@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
GZD3_k127_5346284_24	1122939.ATUD01000002_gene1213	2.182e-13	73.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria,4CQPN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5346284_16	479434.Sthe_1087	1.046e-56	209.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
GZD3_k127_5346284_0	1382306.JNIM01000001_gene2521	2.069e-195	627.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
GZD3_k127_5346284_4	469383.Cwoe_2408	3.881e-144	472.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GZD3_k127_5347071_1	1382306.JNIM01000001_gene1995	3.515e-73	251.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
GZD3_k127_5347071_0	485913.Krac_10815	3.573e-115	378.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
GZD3_k127_5355462_0	1128421.JAGA01000003_gene3701	4.465e-141	463.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
GZD3_k127_5355462_1	479434.Sthe_0045	8.925e-75	263.0	COG0859@1|root,COG0859@2|Bacteria,2GA3U@200795|Chloroflexi,27Z33@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GZD3_k127_5357134_2	525904.Tter_0335	2.587e-126	409.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
GZD3_k127_5357134_4	111780.Sta7437_3373	4.129e-24	112.0	2EAE9@1|root,334HV@2|Bacteria,1GHR4@1117|Cyanobacteria,3VMX1@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5357134_1	429009.Adeg_0107	5.602e-130	429.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD3_k127_5357134_0	485913.Krac_3416	8.74e-198	627.0	COG0477@1|root,COG0477@2|Bacteria,2G84P@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
GZD3_k127_5357134_3	525904.Tter_2446	9.545e-28	122.0	COG2197@1|root,COG2197@2|Bacteria,2NRIC@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
GZD3_k127_5357134_6	1303518.CCALI_01050	1.848e-07	56.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_5359468_0	485913.Krac_10080	1.132e-129	423.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GZD3_k127_5359468_7	667014.Thein_0480	1.26e-05	52.0	COG1826@1|root,COG1826@2|Bacteria,2GI1R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
GZD3_k127_5359468_6	1304275.C41B8_06522	2.059e-17	92.0	COG2062@1|root,COG2062@2|Bacteria,1PKQP@1224|Proteobacteria,1SDUE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
GZD3_k127_5359468_2	485913.Krac_2226	1.309e-104	360.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GZD3_k127_5359468_4	485913.Krac_8463	1.134e-49	184.0	COG0615@1|root,COG0615@2|Bacteria,2G6NJ@200795|Chloroflexi	200795|Chloroflexi	IM	Cytidyltransferase-related domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
GZD3_k127_5359468_1	1382306.JNIM01000001_gene166	6.337e-114	379.0	COG2870@1|root,COG2870@2|Bacteria,2G6G0@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
GZD3_k127_5359468_3	1382306.JNIM01000001_gene167	1.897e-63	228.0	COG1922@1|root,COG1922@2|Bacteria,2G6J0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
GZD3_k127_5359468_5	485913.Krac_6839	4.165e-39	152.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
GZD3_k127_5361900_8	1230341.MJ3_12580	6.164e-11	65.0	COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
GZD3_k127_5361900_6	589924.Ferp_2240	6.92e-30	122.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2466S@183980|Archaeoglobi	183980|Archaeoglobi	O	PFAM Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD3_k127_5361900_7	257310.BB3230	2.817e-29	120.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3T488@506|Alcaligenaceae	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD3_k127_5361900_0	1382306.JNIM01000001_gene2607	3.862e-159	510.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
GZD3_k127_5361900_4	232348.ADXL01000066_gene2725	1.708e-70	247.0	COG1028@1|root,COG1028@2|Bacteria,1G0IE@1117|Cyanobacteria,1GZT8@1129|Synechococcus	1117|Cyanobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
GZD3_k127_5361900_3	485913.Krac_5387	7.923e-80	270.0	COG4430@1|root,COG4430@2|Bacteria,2G8DH@200795|Chloroflexi	200795|Chloroflexi	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
GZD3_k127_5361900_2	1382306.JNIM01000001_gene3665	7.101e-91	312.0	COG2220@1|root,COG2220@2|Bacteria,2G8JY@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
GZD3_k127_5361900_1	479434.Sthe_0072	4.991e-120	423.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
GZD3_k127_5361900_5	41431.PCC8801_2272	5.482e-38	151.0	COG2815@1|root,COG4249@1|root,COG2815@2|Bacteria,COG4249@2|Bacteria,1GAQE@1117|Cyanobacteria	1117|Cyanobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GZD3_k127_5364697_0	1382304.JNIL01000001_gene1434	1.178e-203	638.0	COG1960@1|root,COG1960@2|Bacteria,1UZKG@1239|Firmicutes,4HA6B@91061|Bacilli	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_5364697_1	1382304.JNIL01000001_gene973	1.14e-83	287.0	COG1414@1|root,COG1414@2|Bacteria,1V5M5@1239|Firmicutes,4HMKY@91061|Bacilli,279YU@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
GZD3_k127_5364697_4	485913.Krac_12481	1.958e-34	137.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
GZD3_k127_5364697_2	1382306.JNIM01000001_gene3504	4.104e-60	219.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
GZD3_k127_5364697_3	1382306.JNIM01000001_gene3886	1.727e-40	156.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
GZD3_k127_5370082_9	1382306.JNIM01000001_gene3379	4.872e-56	196.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
GZD3_k127_5370082_5	1382306.JNIM01000001_gene1940	1.788e-84	297.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
GZD3_k127_5370082_10	1382306.JNIM01000001_gene864	2.447e-54	198.0	COG2018@1|root,COG2018@2|Bacteria,2G6ZU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
GZD3_k127_5370082_4	1382306.JNIM01000001_gene865	3.543e-89	297.0	COG1100@1|root,COG1100@2|Bacteria,2G6A7@200795|Chloroflexi	200795|Chloroflexi	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
GZD3_k127_5370082_2	1382306.JNIM01000001_gene3845	4.6e-205	652.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi	200795|Chloroflexi	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
GZD3_k127_5370082_0	1128421.JAGA01000002_gene774	8.914e-273	852.0	COG1164@1|root,COG1164@2|Bacteria,2NNUU@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD3_k127_5370082_18	477974.Daud_0510	1.559e-06	53.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24P7S@186801|Clostridia,26328@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GZD3_k127_5370082_17	324925.Ppha_1038	1.131e-07	57.0	2DZQY@1|root,32VGM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5370082_12	1536774.H70357_11370	9.882e-52	194.0	COG4221@1|root,COG4221@2|Bacteria,1V9C1@1239|Firmicutes,4ISDS@91061|Bacilli,26RJ4@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	XK27_05730	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_5370082_1	485913.Krac_7836	1.383e-205	646.0	COG1960@1|root,COG1960@2|Bacteria,2G7JH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_5370082_3	326427.Cagg_1199	7.995e-103	345.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi,376U9@32061|Chloroflexia	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_5370082_15	749927.AMED_1198	1.756e-18	95.0	28V0X@1|root,2ZH4G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5370082_19	443598.AUFA01000013_gene6558	5.108e-05	51.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,3JYW0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
GZD3_k127_5370082_14	414684.RC1_1176	1.48e-19	91.0	COG2261@1|root,COG2261@2|Bacteria,1NNKP@1224|Proteobacteria,2UGGY@28211|Alphaproteobacteria,2JXIQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD3_k127_5370082_7	485913.Krac_12032	4.699e-72	255.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_5370082_16	1382306.JNIM01000001_gene416	1.957e-13	82.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
GZD3_k127_5370082_6	292459.STH2818	6.992e-79	291.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
GZD3_k127_5370082_8	1121377.KB906415_gene4061	5.438e-59	214.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GZD3_k127_5370082_11	485913.Krac_8761	4.197e-52	195.0	COG3483@1|root,COG3483@2|Bacteria,2G976@200795|Chloroflexi	200795|Chloroflexi	E	Tryptophan 2,3-dioxygenase	-	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
GZD3_k127_5370082_13	1160718.SU9_16332	5.666e-32	125.0	COG2128@1|root,COG2128@2|Bacteria,2IFER@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD3_k127_5370422_0	1382306.JNIM01000001_gene682	5.818e-94	324.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_5370422_3	485913.Krac_11292	4.194e-36	153.0	COG0859@1|root,COG0859@2|Bacteria,2G8F3@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GZD3_k127_5370422_2	485913.Krac_5292	1.987e-66	230.0	COG0237@1|root,COG0237@2|Bacteria	2|Bacteria	H	dephospho-CoA kinase activity	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_18,CoaE
GZD3_k127_5370422_4	369723.Strop_2661	4.236e-27	116.0	COG3293@1|root,COG3293@2|Bacteria,2IKID@201174|Actinobacteria,4DJYB@85008|Micromonosporales	201174|Actinobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
GZD3_k127_5370422_1	42256.RradSPS_2100	7.964e-73	249.0	COG3293@1|root,COG3293@2|Bacteria,2IIMK@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
GZD3_k127_5371761_2	1382306.JNIM01000001_gene162	8.16e-63	224.0	COG0861@1|root,COG0861@2|Bacteria,2G7D5@200795|Chloroflexi	200795|Chloroflexi	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
GZD3_k127_5371761_1	1382306.JNIM01000001_gene697	1.649e-93	336.0	COG2339@1|root,COG2339@2|Bacteria,2G77M@200795|Chloroflexi	200795|Chloroflexi	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GZD3_k127_5371761_0	357808.RoseRS_2983	5.227e-197	626.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,376YP@32061|Chloroflexia	32061|Chloroflexia	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
GZD3_k127_5371761_5	1041930.Mtc_2096	2.722e-18	97.0	COG0697@1|root,arCOG00271@2157|Archaea,2XXKE@28890|Euryarchaeota	28890|Euryarchaeota	G	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_5371761_7	202955.BBND01000004_gene119	0.0005638	48.0	2B098@1|root,31SK4@2|Bacteria,1QQ5I@1224|Proteobacteria,1RSS9@1236|Gammaproteobacteria,3NRM7@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5371761_3	266117.Rxyl_2427	1.529e-57	218.0	2DBRF@1|root,2ZAKB@2|Bacteria,2IIVX@201174|Actinobacteria,4CQPW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5371761_4	207559.Dde_2728	2.296e-19	93.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42TW3@68525|delta/epsilon subdivisions,2WPZS@28221|Deltaproteobacteria,2MC7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
GZD3_k127_5375024_0	1303518.CCALI_01326	1.372e-43	163.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
GZD3_k127_5375024_1	383372.Rcas_1731	1.915e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
GZD3_k127_5387716_1	749414.SBI_05969	4.496e-111	370.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
GZD3_k127_5387716_0	266117.Rxyl_1288	3.903e-127	414.0	COG0491@1|root,COG0491@2|Bacteria,2I9HP@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_5387716_3	485913.Krac_5625	2.105e-79	270.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
GZD3_k127_5387716_4	1382306.JNIM01000001_gene1513	2.523e-34	143.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
GZD3_k127_5387716_2	1382306.JNIM01000001_gene1512	7.995e-89	297.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_5389419_2	1382306.JNIM01000001_gene1179	6.846e-112	374.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
GZD3_k127_5389419_6	211165.AJLN01000146_gene2353	8.595e-40	152.0	COG1943@1|root,COG1943@2|Bacteria,1G5SV@1117|Cyanobacteria,1JKZT@1189|Stigonemataceae	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
GZD3_k127_5389419_0	485913.Krac_11247	6.173e-228	728.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
GZD3_k127_5389419_5	1382306.JNIM01000001_gene2750	4.474e-40	158.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
GZD3_k127_5389419_4	555088.DealDRAFT_2928	6.539e-70	240.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
GZD3_k127_5389419_10	1173027.Mic7113_4389	2.656e-08	59.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5389419_7	373994.Riv7116_1937	1.027e-35	140.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HNNT@1161|Nostocales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
GZD3_k127_5389419_3	1382306.JNIM01000001_gene2749	5.494e-77	270.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
GZD3_k127_5389419_9	485913.Krac_0968	2.99e-12	74.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
GZD3_k127_5389419_1	1382306.JNIM01000001_gene4021	3.467e-180	586.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
GZD3_k127_5389419_8	877411.JMMA01000002_gene276	4.959e-13	69.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
GZD3_k127_5391063_0	1382306.JNIM01000001_gene2710	2.86e-46	183.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
GZD3_k127_5391063_1	485913.Krac_7290	3.378e-33	147.0	COG1295@1|root,COG1295@2|Bacteria,2G7DE@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
GZD3_k127_5392032_2	1382306.JNIM01000001_gene540	3.113e-14	79.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GZD3_k127_5392032_4	1123258.AQXZ01000018_gene630	1.837e-10	65.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4G18K@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
GZD3_k127_5392032_1	266117.Rxyl_2999	2.178e-128	418.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4CPB1@84995|Rubrobacteria	84995|Rubrobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
GZD3_k127_5392032_0	1382306.JNIM01000001_gene145	1.15e-140	479.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
GZD3_k127_5392032_3	1343740.M271_47675	7.049e-12	78.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
GZD3_k127_5392032_5	485913.Krac_0786	3.947e-05	48.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
GZD3_k127_5394842_1	485913.Krac_9059	4.909e-71	242.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Polysacc_synt_3,Polysacc_synt_C
GZD3_k127_5394842_3	1536773.R70331_30475	2.573e-53	191.0	COG4430@1|root,COG4430@2|Bacteria,1TYVP@1239|Firmicutes,4I0UE@91061|Bacilli,26YIC@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
GZD3_k127_5394842_2	485913.Krac_6485	1.57e-64	225.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
GZD3_k127_5394842_5	485913.Krac_0922	2.293e-45	167.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_5394842_0	1122603.ATVI01000005_gene3218	5.26e-249	780.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1X39K@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
GZD3_k127_5394842_6	263358.VAB18032_01405	2.99e-42	166.0	COG1657@1|root,COG1657@2|Bacteria,2IA0T@201174|Actinobacteria,4DB55@85008|Micromonosporales	201174|Actinobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
GZD3_k127_5394842_7	1382306.JNIM01000001_gene1641	6.684e-38	145.0	COG2159@1|root,COG2159@2|Bacteria,2G6EZ@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
GZD3_k127_5395349_2	525904.Tter_1222	3.425e-43	161.0	COG0715@1|root,COG0715@2|Bacteria,2NP6S@2323|unclassified Bacteria	2|Bacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
GZD3_k127_5395349_0	1382306.JNIM01000001_gene3652	1.61e-91	310.0	COG0179@1|root,COG0179@2|Bacteria,2G6HH@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
GZD3_k127_5395349_3	15368.BRADI2G20970.1	9.347e-17	87.0	COG0838@1|root,KOG4662@2759|Eukaryota,37UN0@33090|Viridiplantae,3GISB@35493|Streptophyta,3M6IU@4447|Liliopsida,3II7V@38820|Poales	35493|Streptophyta	C	NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008137,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
GZD3_k127_5395349_1	1382306.JNIM01000001_gene450	1.892e-52	191.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
GZD3_k127_5395778_0	390989.JOEG01000010_gene561	4.609e-136	445.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria,4DCIJ@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_5395778_1	479434.Sthe_3384	2.349e-94	321.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD3_k127_5398700_2	1382306.JNIM01000001_gene422	1.717e-63	234.0	COG0642@1|root,COG2205@2|Bacteria,2GBNP@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
GZD3_k127_5398700_1	485913.Krac_12029	1.955e-68	241.0	COG0745@1|root,COG0745@2|Bacteria,2G8ZD@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5398700_3	866895.HBHAL_5030	2.988e-05	55.0	2EAZJ@1|root,3350E@2|Bacteria,1VGFD@1239|Firmicutes,4HNX8@91061|Bacilli,3NEZQ@45667|Halobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3153
GZD3_k127_5398700_0	469383.Cwoe_4725	9.726e-108	355.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CRGK@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
GZD3_k127_5402699_0	644966.Tmar_0209	1.518e-261	833.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WCFP@538999|Clostridiales incertae sedis	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
GZD3_k127_5402699_1	485913.Krac_0674	1.505e-51	192.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
GZD3_k127_5402699_5	357808.RoseRS_0246	4.177e-16	84.0	arCOG03922@1|root,33G2Q@2|Bacteria,2G9KY@200795|Chloroflexi,3760I@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
GZD3_k127_5402699_2	485913.Krac_8623	2.38e-49	183.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
GZD3_k127_5402699_3	1382306.JNIM01000001_gene128	4.722e-45	166.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
GZD3_k127_5404273_0	357808.RoseRS_0175	2.816e-106	353.0	COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi,376BW@32061|Chloroflexia	32061|Chloroflexia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
GZD3_k127_5404273_1	1382306.JNIM01000001_gene2588	2.079e-55	213.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
GZD3_k127_5415531_0	1089550.ATTH01000001_gene1374	1.066e-171	553.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
GZD3_k127_5415531_2	1227487.C474_06135	7.71e-42	165.0	COG1250@1|root,arCOG00249@2157|Archaea,2XT6B@28890|Euryarchaeota,23SIF@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
GZD3_k127_5415531_1	1382306.JNIM01000001_gene105	6.916e-158	511.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
GZD3_k127_5415531_3	1382306.JNIM01000001_gene1020	2.894e-40	168.0	2DNAS@1|root,32WH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phi_1
GZD3_k127_5428399_3	1122919.KB905650_gene1646	1.617e-06	57.0	COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,275BR@186822|Paenibacillaceae	91061|Bacilli	K	Putative zinc-finger	rsiW	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
GZD3_k127_5428399_1	1128421.JAGA01000002_gene581	3.352e-50	187.0	COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_5428399_0	1047013.AQSP01000017_gene1088	4.991e-104	347.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
GZD3_k127_5428399_2	485913.Krac_6725	1.563e-28	120.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Z2@200795|Chloroflexi	200795|Chloroflexi	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
GZD3_k127_5428866_13	211165.AJLN01000153_gene652	2.113e-22	98.0	COG1598@1|root,COG1598@2|Bacteria,1G7Z6@1117|Cyanobacteria,1JMGC@1189|Stigonemataceae	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_5428866_11	357808.RoseRS_1203	3.97e-35	156.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
GZD3_k127_5428866_15	1207063.P24_02936	8.322e-12	71.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2JPZV@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5428866_4	1382306.JNIM01000001_gene36	9.915e-95	327.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
GZD3_k127_5428866_16	1120948.KB903217_gene1096	7.632e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4E07T@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5428866_10	383372.Rcas_1702	6.778e-44	167.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
GZD3_k127_5428866_6	1122919.KB905582_gene3720	1.007e-75	263.0	COG0388@1|root,COG0388@2|Bacteria,1U2RZ@1239|Firmicutes,4ICEP@91061|Bacilli,272G5@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GZD3_k127_5428866_14	1128421.JAGA01000003_gene3137	5.849e-20	93.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
GZD3_k127_5428866_7	485913.Krac_6355	3.701e-54	193.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD3_k127_5428866_3	326427.Cagg_1199	6.701e-100	339.0	COG0675@1|root,COG0675@2|Bacteria,2G8AM@200795|Chloroflexi,376U9@32061|Chloroflexia	200795|Chloroflexi	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_5428866_5	357808.RoseRS_0423	7.179e-88	295.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
GZD3_k127_5428866_9	1382306.JNIM01000001_gene3502	8.771e-53	199.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GZD3_k127_5428866_2	1382306.JNIM01000001_gene2666	6.014e-103	366.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
GZD3_k127_5428866_8	1463857.JOFZ01000012_gene1844	6.54e-53	201.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
GZD3_k127_5428866_1	1459636.NTE_02520	1.987e-116	390.0	COG1914@1|root,arCOG04531@2157|Archaea	2157|Archaea	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD3_k127_5428866_12	192952.MM_3100	1.632e-31	132.0	COG0727@1|root,arCOG02583@2157|Archaea	2157|Archaea	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
GZD3_k127_5428866_0	1128421.JAGA01000004_gene2510	3.303e-155	498.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
GZD3_k127_5433799_1	42256.RradSPS_0711	4.068e-117	395.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria	201174|Actinobacteria	CH	tryptophan 2,3-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
GZD3_k127_5433799_0	383372.Rcas_0160	1.326e-181	579.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi,37571@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
GZD3_k127_5437276_1	1382306.JNIM01000001_gene646	5.053e-54	207.0	COG0859@1|root,COG0859@2|Bacteria,2G8F3@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GZD3_k127_5437276_0	485913.Krac_11290	1.726e-87	310.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
GZD3_k127_5437276_2	485913.Krac_9186	3.443e-34	136.0	COG0613@1|root,COG0613@2|Bacteria,2G71S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
GZD3_k127_5437543_0	525904.Tter_0413	3.293e-205	650.0	COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
GZD3_k127_5437543_1	1382356.JQMP01000003_gene1988	1.355e-121	404.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
GZD3_k127_5437543_2	1382306.JNIM01000001_gene766	1.37e-63	225.0	COG0166@1|root,COG0166@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
GZD3_k127_5443167_0	1382306.JNIM01000001_gene700	2.125e-125	419.0	COG0508@1|root,COG0508@2|Bacteria,2G5TB@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD3_k127_5443167_1	469383.Cwoe_5815	7.537e-87	295.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CPF7@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
GZD3_k127_5444150_0	1382306.JNIM01000001_gene451	1.307e-189	597.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
GZD3_k127_5444150_2	485913.Krac_11998	8.406e-123	407.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
GZD3_k127_5444150_5	710685.MycrhN_1139	5.262e-29	123.0	COG0748@1|root,COG0748@2|Bacteria,2IN9W@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_5444150_6	390989.JOEG01000028_gene5455	5.44e-28	119.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
GZD3_k127_5444150_8	497964.CfE428DRAFT_3295	5.435e-17	86.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	linF	-	-	ko:K18236	-	-	-	-	ko00000,ko01504	-	-	-	Adenyl_transf,DUF4037,NTP_transf_2
GZD3_k127_5444150_9	32057.KB217478_gene6636	7.926e-17	82.0	COG1724@1|root,COG1724@2|Bacteria,1G8YW@1117|Cyanobacteria,1HT49@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
GZD3_k127_5444150_7	163908.KB235896_gene2826	1.251e-21	96.0	COG1598@1|root,COG1598@2|Bacteria,1G8ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_5444150_10	118173.KB235910_gene4565	9.256e-08	58.0	2DQDR@1|root,3366A@2|Bacteria,1G9QS@1117|Cyanobacteria,1HCYA@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281
GZD3_k127_5444150_4	118173.KB235910_gene4566	8.523e-36	140.0	COG2337@1|root,COG2337@2|Bacteria,1G7FR@1117|Cyanobacteria,1HHJS@1150|Oscillatoriales	1117|Cyanobacteria	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
GZD3_k127_5444150_3	717606.PaecuDRAFT_4640	2.602e-60	217.0	28PVT@1|root,2ZCGB@2|Bacteria,1V3TG@1239|Firmicutes,4HHU4@91061|Bacilli,26UN6@186822|Paenibacillaceae	91061|Bacilli	-	-	yoxB	-	-	-	-	-	-	-	-	-	-	-	UDG
GZD3_k127_5444150_1	485913.Krac_6817	3.353e-130	429.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
GZD3_k127_5452315_4	1121877.JQKF01000020_gene2501	1.982e-49	181.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_5452315_3	525909.Afer_0505	5.873e-85	291.0	COG0411@1|root,COG0411@2|Bacteria,2I3Z1@201174|Actinobacteria,4CP54@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
GZD3_k127_5452315_0	525909.Afer_0506	5.677e-106	356.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CN85@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_5452315_2	1121877.JQKF01000020_gene2498	2.236e-87	297.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CN5E@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
GZD3_k127_5452315_1	485913.Krac_2239	8.563e-106	348.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5453315_13	1282360.ABAC460_03055	1.004e-10	63.0	COG2267@1|root,COG2267@2|Bacteria,1QXHW@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_5453315_0	1128421.JAGA01000001_gene2227	6.68e-221	693.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	atzB	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
GZD3_k127_5453315_14	867903.ThesuDRAFT_01114	5.384e-06	49.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
GZD3_k127_5453315_3	485913.Krac_9557	6.563e-150	498.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
GZD3_k127_5453315_10	485918.Cpin_2425	3.438e-45	171.0	COG0262@1|root,COG0262@2|Bacteria,4NSY9@976|Bacteroidetes,1J05F@117747|Sphingobacteriia	976|Bacteroidetes	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_5453315_9	485913.Krac_6351	1.663e-59	211.0	COG3195@1|root,COG3195@2|Bacteria,2G8S1@200795|Chloroflexi	200795|Chloroflexi	S	OHCU decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox
GZD3_k127_5453315_12	1408254.T458_08005	1.179e-31	133.0	COG1514@1|root,COG1514@2|Bacteria,1VBG1@1239|Firmicutes	1239|Firmicutes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
GZD3_k127_5453315_15	1397278.AYMV01000018_gene839	4.337e-05	46.0	COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria,4FQRW@85023|Microbacteriaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
GZD3_k127_5453315_5	485913.Krac_6350	4.294e-100	337.0	COG3648@1|root,COG3648@2|Bacteria,2G7WX@200795|Chloroflexi	200795|Chloroflexi	Q	Uricase	-	-	-	-	-	-	-	-	-	-	-	-	Uricase
GZD3_k127_5453315_11	864702.OsccyDRAFT_0978	1.885e-44	164.0	COG2351@1|root,COG2351@2|Bacteria,1G806@1117|Cyanobacteria,1HBWH@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
GZD3_k127_5453315_4	1128421.JAGA01000001_gene2232	5.122e-133	436.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iPC815.YPO3249	M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28
GZD3_k127_5453315_6	1267533.KB906734_gene3781	7.185e-81	272.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4,IU_nuc_hydro
GZD3_k127_5453315_7	399795.CtesDRAFT_PD3148	6.437e-78	269.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VK16@28216|Betaproteobacteria,4ACKC@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
GZD3_k127_5453315_8	114615.BRADO3705	5.567e-72	251.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,2U58G@28211|Alphaproteobacteria,3K3YU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
GZD3_k127_5453315_2	675635.Psed_5497	2.274e-157	507.0	COG1960@1|root,COG1960@2|Bacteria,2IBGY@201174|Actinobacteria,4E3U2@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
GZD3_k127_5453315_1	485913.Krac_6173	9.806e-201	634.0	COG2079@1|root,COG2079@2|Bacteria,2G7JZ@200795|Chloroflexi	200795|Chloroflexi	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
GZD3_k127_5461377_3	941449.dsx2_1429	1.275e-12	75.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
GZD3_k127_5461377_2	1122222.AXWR01000023_gene1539	3.041e-20	93.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
GZD3_k127_5461377_1	1382306.JNIM01000001_gene778	9.735e-60	211.0	COG0245@1|root,COG0245@2|Bacteria,2G6RA@200795|Chloroflexi	200795|Chloroflexi	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
GZD3_k127_5461377_0	414684.RC1_3530	3.282e-84	287.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,2JYME@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
GZD3_k127_5462955_2	485913.Krac_4700	8.017e-59	217.0	2DRZ7@1|root,33DSV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5462955_3	1382306.JNIM01000001_gene1924	2.255e-49	181.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
GZD3_k127_5462955_1	485913.Krac_6813	3.119e-79	270.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
GZD3_k127_5462955_7	257310.BB1207	0.0001903	52.0	COG1708@1|root,COG1708@2|Bacteria,1R03C@1224|Proteobacteria,2WB33@28216|Betaproteobacteria,3T40C@506|Alcaligenaceae	28216|Betaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5462955_0	208439.AJAP_18030	9.63e-113	376.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4E85Q@85010|Pseudonocardiales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
GZD3_k127_5462955_4	1120949.KB903341_gene9721	1.56e-34	136.0	COG0346@1|root,COG0346@2|Bacteria,2HWNF@201174|Actinobacteria,4DJNN@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5462955_6	1121335.Clst_1028	3.364e-05	46.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
GZD3_k127_5465279_6	485913.Krac_12276	4.601e-07	61.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
GZD3_k127_5465279_5	374847.Kcr_0713	3.559e-07	58.0	COG2442@1|root,arCOG07520@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
GZD3_k127_5465279_9	272134.KB731324_gene5489	0.0007364	48.0	2B73C@1|root,32049@2|Bacteria,1GKM3@1117|Cyanobacteria,1HG0W@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5465279_8	1173029.JH980292_gene471	5.622e-05	48.0	COG1848@1|root,COG1848@2|Bacteria,1G8A3@1117|Cyanobacteria,1HHJ5@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_5465279_1	1382306.JNIM01000001_gene4101	1.983e-60	232.0	COG5002@1|root,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_5465279_0	1382306.JNIM01000001_gene4100	4.848e-105	349.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5465279_3	525904.Tter_0497	9.834e-34	140.0	2F2ZT@1|root,33VV3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5465279_2	1382306.JNIM01000001_gene3869	1.01e-36	145.0	COG3729@1|root,COG3729@2|Bacteria	2|Bacteria	D	General stress protein	gsiB	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	AHH,KGG,LEA_5,YjzC
GZD3_k127_5465279_4	1298858.AUEL01000031_gene3788	8.146e-15	81.0	COG3685@1|root,COG3685@2|Bacteria,1R4MJ@1224|Proteobacteria,2U9EB@28211|Alphaproteobacteria,43P4A@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
GZD3_k127_5465827_6	926550.CLDAP_05940	1.336e-07	57.0	COG0697@1|root,COG0697@2|Bacteria,2G7DS@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_5465827_0	469383.Cwoe_0346	3.064e-159	519.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CPI3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_5465827_1	42256.RradSPS_2838	1.139e-108	355.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4CQ0T@84995|Rubrobacteria	84995|Rubrobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_5465827_2	485913.Krac_6898	4.046e-91	307.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
GZD3_k127_5465827_3	485913.Krac_7300	2.027e-62	232.0	COG4977@1|root,COG4977@2|Bacteria,2G8UD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
GZD3_k127_5465827_5	178306.PAE0983	1.016e-13	75.0	COG2509@1|root,arCOG02231@2157|Archaea,2XPNU@28889|Crenarchaeota	28889|Crenarchaeota	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
GZD3_k127_5467509_1	1382306.JNIM01000001_gene2677	7.509e-53	192.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
GZD3_k127_5467509_0	1382306.JNIM01000001_gene3404	1.417e-109	367.0	COG1432@1|root,COG1432@2|Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
GZD3_k127_5478841_5	357808.RoseRS_3982	1.278e-14	83.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,375DY@32061|Chloroflexia	32061|Chloroflexia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
GZD3_k127_5478841_0	485913.Krac_5576	1.244e-166	542.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_5478841_4	485913.Krac_4692	1.77e-38	154.0	COG1309@1|root,COG1309@2|Bacteria,2G9G4@200795|Chloroflexi	2|Bacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
GZD3_k127_5478841_3	485913.Krac_11918	5.679e-63	221.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
GZD3_k127_5478841_1	1382306.JNIM01000001_gene2893	8.738e-121	396.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
GZD3_k127_5478841_2	1382306.JNIM01000001_gene2829	1.028e-104	350.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N,Peptidase_S8
GZD3_k127_5496401_7	243090.RB7894	1.253e-13	70.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
GZD3_k127_5496401_3	1382306.JNIM01000001_gene3550	7.198e-52	184.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
GZD3_k127_5496401_1	1382306.JNIM01000001_gene3549	1.014e-77	270.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
GZD3_k127_5496401_2	485913.Krac_12527	8.915e-68	244.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
GZD3_k127_5496401_6	485913.Krac_12526	1.169e-20	94.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
GZD3_k127_5496401_0	485913.Krac_12525	2.205e-140	450.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
GZD3_k127_5496401_4	485913.Krac_12524	1.727e-43	160.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
GZD3_k127_5496401_5	485913.Krac_12523	5.05e-28	118.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
GZD3_k127_5496916_0	1382306.JNIM01000001_gene574	5.887e-173	552.0	COG1502@1|root,COG1502@2|Bacteria,2G7KK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD3_k127_5496916_1	2325.TKV_c18380	8.556e-149	478.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,42F68@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GZD3_k127_5499073_0	485913.Krac_1214	4.611e-192	629.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi	2|Bacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD3_k127_5499073_1	485913.Krac_12349	2.347e-39	158.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
GZD3_k127_5499073_2	1123008.KB905694_gene1888	0.0001792	48.0	2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia,22YX8@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5500055_13	526218.Sterm_3771	1.477e-20	92.0	COG0022@1|root,COG0022@2|Bacteria,379FG@32066|Fusobacteria	32066|Fusobacteria	C	domain protein	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
GZD3_k127_5500055_2	671143.DAMO_1598	1.01e-100	339.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
GZD3_k127_5500055_10	485913.Krac_1496	1.4e-35	141.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
GZD3_k127_5500055_14	485913.Krac_8434	4.511e-15	78.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
GZD3_k127_5500055_11	266940.Krad_4103	2.463e-29	131.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
GZD3_k127_5500055_6	485913.Krac_2323	8.843e-56	213.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yabI	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0050896,GO:0051301,GO:0071944	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LssY_C,PAP2,SNARE_assoc
GZD3_k127_5500055_4	1382306.JNIM01000001_gene162	6.478e-60	218.0	COG0861@1|root,COG0861@2|Bacteria,2G7D5@200795|Chloroflexi	200795|Chloroflexi	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
GZD3_k127_5500055_1	485913.Krac_8059	8.942e-114	380.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
GZD3_k127_5500055_9	1303518.CCALI_00671	1.69e-39	154.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
GZD3_k127_5500055_3	592015.HMPREF1705_00546	2.753e-61	217.0	COG0279@1|root,COG0279@2|Bacteria,3TB1U@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
GZD3_k127_5500055_0	592015.HMPREF1705_00545	7.367e-145	472.0	COG2605@1|root,COG2605@2|Bacteria,3TC8T@508458|Synergistetes	508458|Synergistetes	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
GZD3_k127_5500055_7	272562.CA_C3056	3.642e-54	198.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,36UK6@31979|Clostridiaceae	186801|Clostridia	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	gmhB	-	2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83,5.4.2.8	ko:K00966,ko:K03273,ko:K15669,ko:K16881	ko00051,ko00520,ko00540,ko01100,ko01110,ko01130,map00051,map00520,map00540,map01100,map01110,map01130	M00064,M00114,M00361,M00362	R00885,R01818,R05647,R09771,R09772	RC00002,RC00017,RC00408	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hydrolase_like,NTP_transferase,PNK3P
GZD3_k127_5500055_5	485913.Krac_7501	1.7e-57	202.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
GZD3_k127_5500055_8	404380.Gbem_1581	2.057e-42	160.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_5505672_1	1117943.SFHH103_02690	3.493e-73	262.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TT05@28211|Alphaproteobacteria,4B80G@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Flavin-binding monooxygenase-like	trxBch	-	1.14.13.168	ko:K11816	ko00380,ko01100,map00380,map01100	-	R10181	RC00866	ko00000,ko00001,ko01000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
GZD3_k127_5505672_2	41431.PCC8801_2272	5.098e-38	151.0	COG2815@1|root,COG4249@1|root,COG2815@2|Bacteria,COG4249@2|Bacteria,1GAQE@1117|Cyanobacteria	1117|Cyanobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
GZD3_k127_5505672_0	485913.Krac_2103	1.69e-124	404.0	COG1132@1|root,COG1132@2|Bacteria,2G7QD@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
GZD3_k127_5509707_0	1382306.JNIM01000001_gene2539	1.066e-59	226.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CbiA,NB-ARC,TIR_2,TPR_10,TPR_12
GZD3_k127_5509707_1	1382306.JNIM01000001_gene3894	1.368e-10	67.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
GZD3_k127_5516842_2	312284.A20C1_08939	2.2e-142	462.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,3UXNV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
GZD3_k127_5516842_0	1283283.ATXA01000021_gene2851	2.976e-230	720.0	COG0044@1|root,COG0044@2|Bacteria,2IARA@201174|Actinobacteria	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
GZD3_k127_5516842_1	1283283.ATXA01000021_gene2850	1.828e-171	544.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_5516842_4	1283283.ATXA01000021_gene2849	3.959e-104	345.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,4EW2R@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
GZD3_k127_5516842_5	1283283.ATXA01000021_gene2848	4.486e-97	324.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
GZD3_k127_5516842_7	1207063.P24_08379	1.138e-18	95.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2JRJV@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
GZD3_k127_5516842_6	1283283.ATXA01000021_gene2853	1.235e-61	220.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD3_k127_5520434_0	1382306.JNIM01000001_gene4108	6.349e-241	779.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
GZD3_k127_5520434_5	1120950.KB892742_gene3009	1.237e-68	243.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4DQY9@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
GZD3_k127_5520434_7	1382306.JNIM01000001_gene539	1.184e-17	87.0	2EIKM@1|root,33CBX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5520434_1	485913.Krac_8237	1.375e-124	413.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
GZD3_k127_5520434_6	479434.Sthe_3462	2.423e-53	192.0	COG1695@1|root,COG1695@2|Bacteria,2G99R@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
GZD3_k127_5520434_4	485913.Krac_3470	2.077e-76	263.0	COG1272@1|root,COG1272@2|Bacteria,2G7B7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Hly-III family protein	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
GZD3_k127_5520434_2	323261.Noc_2686	1.835e-104	351.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_5520434_3	1382306.JNIM01000001_gene3852	8.708e-88	304.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
GZD3_k127_5552534_0	1128421.JAGA01000004_gene2610	1.09e-254	795.0	COG2225@1|root,COG2225@2|Bacteria	2|Bacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	aceB	GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010	Malate_synthase
GZD3_k127_5552534_6	264732.Moth_1799	1.607e-09	62.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24T0M@186801|Clostridia,42H3E@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
GZD3_k127_5552534_3	1120950.KB892708_gene4319	2.791e-131	430.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4DREI@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
GZD3_k127_5552534_2	235985.BBPN01000014_gene5397	8.974e-201	637.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,2NHP7@228398|Streptacidiphilus	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GZD3_k127_5552534_1	485913.Krac_5302	5.058e-214	671.0	COG0596@1|root,COG0596@2|Bacteria,2G8GA@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GZD3_k127_5552534_5	58123.JOFJ01000020_gene3715	8.78e-76	259.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4EJDM@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_5552534_4	485913.Krac_7653	4.435e-91	305.0	COG0491@1|root,COG0491@2|Bacteria,2G8CE@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
GZD3_k127_5552534_7	485913.Krac_0379	4.176e-09	60.0	2DRAK@1|root,33AYS@2|Bacteria	485913.Krac_0379|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5552534_8	1123320.KB889686_gene817	8.661e-05	46.0	COG2267@1|root,COG2267@2|Bacteria,2HJ2M@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD3_k127_5558481_3	1382306.JNIM01000001_gene1906	7.459e-86	285.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
GZD3_k127_5558481_1	1382306.JNIM01000001_gene1569	5.199e-153	499.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GZD3_k127_5558481_4	153721.MYP_382	1.051e-13	72.0	COG3119@1|root,COG3119@2|Bacteria,4NS5B@976|Bacteroidetes	976|Bacteroidetes	P	Protein of unknown function (DUF229)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
GZD3_k127_5558481_2	485913.Krac_7933	3.67e-120	402.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_5558481_5	357808.RoseRS_0339	2.31e-08	64.0	COG3427@1|root,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GZD3_k127_5558481_0	485913.Krac_9133	4.182e-157	515.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
GZD3_k127_5563268_0	485913.Krac_11708	2.578e-06	49.0	COG2197@1|root,COG2909@1|root,COG3903@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
GZD3_k127_5569731_1	404589.Anae109_2517	1.311e-55	199.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
GZD3_k127_5569731_3	391735.Veis_1572	0.0006984	51.0	2CA9G@1|root,32TWH@2|Bacteria,1NFGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5569731_0	1120948.KB903226_gene5506	2.31e-93	328.0	COG3511@1|root,COG3511@2|Bacteria,2IS02@201174|Actinobacteria,4EADP@85010|Pseudonocardiales	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
GZD3_k127_5571466_1	926550.CLDAP_02510	1.18e-14	83.0	COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi	200795|Chloroflexi	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
GZD3_k127_5571466_0	1382356.JQMP01000003_gene2420	1.179e-256	804.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
GZD3_k127_5573883_3	926551.KB900715_gene2212	0.0002586	47.0	2DP84@1|root,330YJ@2|Bacteria,4NV1T@976|Bacteroidetes,1I5CN@117743|Flavobacteriia,1ET79@1016|Capnocytophaga	976|Bacteroidetes	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
GZD3_k127_5573883_2	391612.CY0110_20343	2.081e-15	78.0	COG2336@1|root,COG2336@2|Bacteria,1GMNA@1117|Cyanobacteria,3KKM8@43988|Cyanothece	1117|Cyanobacteria	K	PFAM SpoVT AbrB	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5573883_0	1282361.ABAC402_00075	2.864e-27	115.0	COG4374@1|root,COG4374@2|Bacteria,1N7EF@1224|Proteobacteria,2UFJV@28211|Alphaproteobacteria,2KJ4M@204458|Caulobacterales	204458|Caulobacterales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_5573883_1	1382356.JQMP01000003_gene1537	1.437e-22	103.0	COG1846@1|root,COG1846@2|Bacteria,2G7D6@200795|Chloroflexi,27Z9E@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
GZD3_k127_5579924_4	1125779.HMPREF1219_00259	0.0004032	51.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,22KGP@1653|Corynebacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_5579924_3	1137269.AZWL01000013_gene2723	7.018e-13	83.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	1137269.AZWL01000013_gene2723|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5579924_0	240292.Ava_C0142	1.228e-64	226.0	COG1651@1|root,COG1651@2|Bacteria,1G2ZB@1117|Cyanobacteria,1HP1D@1161|Nostocales	1117|Cyanobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
GZD3_k127_5579924_1	468556.AQYG01000030_gene2809	7.245e-57	220.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4GARS@85026|Gordoniaceae	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
GZD3_k127_5579924_2	266117.Rxyl_3030	7.696e-16	82.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	xylB	-	2.7.1.12,2.7.1.17,2.7.1.5	ko:K00848,ko:K00851,ko:K00854	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU17610	FGGY_C,FGGY_N
GZD3_k127_5587554_3	485913.Krac_6709	2.494e-72	250.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
GZD3_k127_5587554_4	909663.KI867150_gene1232	2.284e-58	219.0	COG1085@1|root,COG1085@2|Bacteria,1N3RW@1224|Proteobacteria,42NEE@68525|delta/epsilon subdivisions,2WMGC@28221|Deltaproteobacteria,2MRWF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5587554_8	1382306.JNIM01000001_gene3009	3.465e-17	89.0	COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi	200795|Chloroflexi	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	-	-	-	-	-	-	-	-	-	CRCB
GZD3_k127_5587554_9	1382306.JNIM01000001_gene3007	1.206e-10	70.0	COG1993@1|root,COG1993@2|Bacteria	2|Bacteria	T	acr, cog1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
GZD3_k127_5587554_7	1382306.JNIM01000001_gene3008	2.311e-19	92.0	COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi	200795|Chloroflexi	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
GZD3_k127_5587554_1	485913.Krac_7369	2.265e-163	529.0	COG0492@1|root,COG0492@2|Bacteria,2G83X@200795|Chloroflexi	200795|Chloroflexi	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
GZD3_k127_5587554_6	40571.JOEA01000025_gene6042	4.146e-24	106.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
GZD3_k127_5587554_0	426117.M446_5171	0.0	2499.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,1JZII@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,Response_reg,TPR_12
GZD3_k127_5587554_2	1300345.LF41_1550	4.469e-73	261.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1RQ3H@1236|Gammaproteobacteria,1X3SI@135614|Xanthomonadales	135614|Xanthomonadales	T	two-component system sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
GZD3_k127_5587554_5	1254432.SCE1572_19175	4.849e-26	111.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
GZD3_k127_5589501_1	479434.Sthe_1906	1.328e-174	568.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
GZD3_k127_5589501_2	1254432.SCE1572_49735	7.555e-57	209.0	COG2227@1|root,COG2227@2|Bacteria,1R7WN@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
GZD3_k127_5589501_0	485913.Krac_8409	2.29e-274	853.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
GZD3_k127_5595085_4	1122619.KB892284_gene1911	2.738e-06	50.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,3T3TN@506|Alcaligenaceae	28216|Betaproteobacteria	O	redox protein regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GZD3_k127_5595085_0	485913.Krac_4754	9.788e-70	239.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
GZD3_k127_5595085_2	479432.Sros_1172	6.38e-27	118.0	COG1595@1|root,COG1595@2|Bacteria,2IJ11@201174|Actinobacteria,4EPIJ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD3_k127_5595085_3	390989.JOEG01000013_gene2409	4.029e-11	76.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4DFG8@85008|Micromonosporales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5595085_1	298654.FraEuI1c_3194	1.2e-59	213.0	2AP53@1|root,31E6R@2|Bacteria,2IPBQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5628729_2	1499967.BAYZ01000027_gene1768	4.1e-38	161.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,NACHT,NPCBM,PEGA,Pkinase
GZD3_k127_5628729_0	1128421.JAGA01000002_gene1419	3.628e-236	745.0	COG0366@1|root,COG0366@2|Bacteria,2NQFF@2323|unclassified Bacteria	2|Bacteria	G	Alpha-amylase domain	malL	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
GZD3_k127_5628729_1	485913.Krac_8202	9.194e-48	176.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
GZD3_k127_5628729_4	290397.Adeh_2803	9.652e-14	81.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
GZD3_k127_5628729_3	1382306.JNIM01000001_gene1240	2.929e-36	144.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
GZD3_k127_5642181_0	1382306.JNIM01000001_gene3568	2.276e-111	376.0	COG1630@1|root,COG1630@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
GZD3_k127_5642181_1	1382306.JNIM01000001_gene1066	4.584e-46	190.0	COG0642@1|root,COG2205@2|Bacteria	1382306.JNIM01000001_gene1066|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5652349_0	485913.Krac_8124	2.469e-84	285.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	2|Bacteria	O	ATPase AAA-2 domain protein	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
GZD3_k127_5652349_3	1174528.JH992898_gene743	2.845e-25	110.0	COG1943@1|root,COG1943@2|Bacteria,1G603@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
GZD3_k127_5652349_4	1463825.JNXC01000005_gene2397	0.0004226	45.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
GZD3_k127_5652349_2	448385.sce1494	5.028e-29	126.0	COG0515@1|root,COG0642@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1R72I@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,AAA_16,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_7,Pkinase
GZD3_k127_5652349_1	479434.Sthe_2768	4.618e-58	212.0	COG3253@1|root,COG3253@2|Bacteria,2G6WY@200795|Chloroflexi,27Y5N@189775|Thermomicrobia	189775|Thermomicrobia	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
GZD3_k127_565417_0	316274.Haur_4553	3.855e-109	372.0	COG0514@1|root,COG0514@2|Bacteria,2G6S8@200795|Chloroflexi,376TB@32061|Chloroflexia	32061|Chloroflexia	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
GZD3_k127_5655923_0	330214.NIDE1834	6.177e-100	339.0	COG3547@1|root,COG3547@2|Bacteria,3J17W@40117|Nitrospirae	40117|Nitrospirae	L	hmm pf02371	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
GZD3_k127_5655923_1	485913.Krac_3339	2.205e-06	50.0	COG0596@1|root,COG0596@2|Bacteria,2G8GA@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	EHN
GZD3_k127_5668244_1	485913.Krac_5377	8.254e-87	290.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
GZD3_k127_5668244_3	485913.Krac_5378	1.105e-65	242.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
GZD3_k127_5668244_6	1120971.AUCA01000001_gene1821	6.178e-10	69.0	COG2318@1|root,COG2318@2|Bacteria,1VBVV@1239|Firmicutes,4HNA7@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
GZD3_k127_5668244_2	485913.Krac_7281	2.469e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_5668244_5	1244869.H261_15632	2.088e-12	70.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,2JQZ4@204441|Rhodospirillales	204441|Rhodospirillales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD3_k127_5668244_4	926550.CLDAP_13520	6.544e-14	74.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD3_k127_5668244_0	1382306.JNIM01000001_gene1362	1.2e-268	843.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
GZD3_k127_5687370_4	1521187.JPIM01000021_gene147	2.539e-35	144.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi,376Z6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
GZD3_k127_5687370_5	869210.Marky_1265	2.038e-34	148.0	COG1853@1|root,COG1853@2|Bacteria,1WKCR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1853 Conserved protein domain typically associated with flavoprotein oxygenase DIM6 NTAB family	-	-	1.5.1.36	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	-	R02698,R03299,R05705,R09748,R09750	RC00046,RC00126	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
GZD3_k127_5687370_0	1382306.JNIM01000001_gene3853	4.025e-149	479.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
GZD3_k127_5687370_3	1382306.JNIM01000001_gene2904	5.721e-38	148.0	COG2320@1|root,COG2320@2|Bacteria,2G94B@200795|Chloroflexi	200795|Chloroflexi	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
GZD3_k127_5687370_2	1174528.JH992898_gene938	7.251e-105	353.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5687370_6	1118054.CAGW01000018_gene4253	5.663e-09	66.0	2E2PT@1|root,32XSN@2|Bacteria,1VED4@1239|Firmicutes,4IB0Y@91061|Bacilli,273HS@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5687370_1	485913.Krac_8662	3.305e-134	440.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD3_k127_570526_1	1206733.BAGC01000048_gene2354	6.932e-07	61.0	COG1051@1|root,COG1051@2|Bacteria,2I2P7@201174|Actinobacteria,4FW5K@85025|Nocardiaceae	201174|Actinobacteria	F	Glycosyltransferase family 87	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87,NUDIX
GZD3_k127_5722004_3	1382306.JNIM01000001_gene4040	7.02e-41	160.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GZD3_k127_5722004_1	1382306.JNIM01000001_gene4039	2.914e-113	374.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
GZD3_k127_5722004_2	1382306.JNIM01000001_gene4032	9.66e-75	272.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,2G8T7@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
GZD3_k127_5722004_0	485913.Krac_12030	2.437e-259	814.0	COG0445@1|root,COG0445@2|Bacteria,2G629@200795|Chloroflexi	200795|Chloroflexi	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
GZD3_k127_5726700_4	1304865.JAGF01000001_gene2445	1.442e-28	125.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
GZD3_k127_5726700_7	273068.TTE0132	1.708e-07	56.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,24UXU@186801|Clostridia,42HA3@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
GZD3_k127_5726700_6	1195236.CTER_3891	9.884e-11	70.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia,3WPWD@541000|Ruminococcaceae	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
GZD3_k127_5726700_3	269799.Gmet_3329	9.05e-43	164.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria,43VTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
GZD3_k127_5726700_2	1232410.KI421412_gene145	1.483e-65	233.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2X8MJ@28221|Deltaproteobacteria,43TMS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
GZD3_k127_5726700_0	240015.ACP_3053	7.082e-262	816.0	COG0374@1|root,COG0374@2|Bacteria,3Y3C2@57723|Acidobacteria,2JJUU@204432|Acidobacteriia	204432|Acidobacteriia	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
GZD3_k127_5726700_1	765420.OSCT_1632	1.585e-140	458.0	COG1740@1|root,COG1740@2|Bacteria,2G8F0@200795|Chloroflexi,376S5@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM hydrogenase (NiFe) small subunit HydA	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
GZD3_k127_5726700_5	479434.Sthe_2605	6.613e-18	84.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia	189775|Thermomicrobia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
GZD3_k127_5732723_1	485913.Krac_11802	3.868e-33	133.0	COG3832@1|root,COG3832@2|Bacteria,2G9IK@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
GZD3_k127_5732723_3	1123508.JH636439_gene1858	0.0001615	53.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GZD3_k127_5732723_0	485913.Krac_11078	2.402e-43	163.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
GZD3_k127_5772336_1	345341.KUTG_08092	1.304e-29	129.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD3_k127_5772336_0	1968.JOEV01000042_gene8395	1.453e-127	426.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
GZD3_k127_5773324_0	1382306.JNIM01000001_gene1964	2.854e-153	497.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
GZD3_k127_5773324_6	926569.ANT_17200	0.0005221	45.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
GZD3_k127_5773324_1	1303518.CCALI_00397	1.42e-75	266.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
GZD3_k127_5773324_4	794903.OPIT5_09325	3.662e-13	82.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,46VQN@74201|Verrucomicrobia,3K8HG@414999|Opitutae	414999|Opitutae	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5773324_2	485913.Krac_3453	4.796e-54	194.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
GZD3_k127_5773324_3	1382306.JNIM01000001_gene2571	1.003e-21	104.0	COG0526@1|root,COG0526@2|Bacteria,2G7HX@200795|Chloroflexi	200795|Chloroflexi	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
GZD3_k127_5773324_5	485913.Krac_12575	3.616e-05	50.0	COG1835@1|root,COG1835@2|Bacteria,2G7EM@200795|Chloroflexi	200795|Chloroflexi	I	PFAM acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GZD3_k127_5774375_7	525904.Tter_0838	0.0008989	42.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	prpA1	-	3.1.3.16,6.5.1.3	ko:K01090,ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
GZD3_k127_5774375_2	485913.Krac_12131	1.214e-94	316.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	2|Bacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GZD3_k127_5774375_3	1382306.JNIM01000001_gene3809	2.195e-53	199.0	COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
GZD3_k127_5774375_6	1157635.KB892041_gene5898	1.01e-24	106.0	2EF5E@1|root,31KM2@2|Bacteria,2IKZ8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5774375_0	485913.Krac_11768	3.965e-264	837.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
GZD3_k127_5774375_4	296591.Bpro_3192	4.456e-38	146.0	2AGAH@1|root,316G1@2|Bacteria,1N2FZ@1224|Proteobacteria,2WDAY@28216|Betaproteobacteria,4AIKB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
GZD3_k127_5774375_1	1121377.KB906436_gene921	1.141e-241	775.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
GZD3_k127_5774375_5	1382356.JQMP01000001_gene1200	1.227e-28	132.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD3_k127_5793577_2	204773.HEAR2529	9.756e-18	84.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,1RDAY@1224|Proteobacteria,2VQGW@28216|Betaproteobacteria,4777D@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH
GZD3_k127_5793577_0	309801.trd_A0910	1.788e-50	184.0	COG1881@1|root,COG1881@2|Bacteria,2G6ZP@200795|Chloroflexi,27Z5Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
GZD3_k127_5793577_1	555088.DealDRAFT_2995	4.576e-31	138.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,42JXA@68298|Syntrophomonadaceae	186801|Clostridia	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
GZD3_k127_5793577_3	926550.CLDAP_22960	1.04e-10	74.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G7WA@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
GZD3_k127_5794673_2	1357275.AVEL02000078_gene1917	1.558e-16	85.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1Z6TM@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	O	Belongs to the peptidase S1C family	degS	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_5794673_1	485913.Krac_6697	3.521e-32	129.0	COG0675@1|root,COG0675@2|Bacteria,2G8WI@200795|Chloroflexi	2|Bacteria	L	TIGRFAM transposase, IS605 OrfB family, central region	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
GZD3_k127_5794673_0	485913.Krac_10686	7.771e-58	207.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2G82S@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A7NFQ2 Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
GZD3_k127_581688_6	1395587.P364_0100595	3.658e-42	161.0	COG0454@1|root,COG0456@2|Bacteria,1V81Z@1239|Firmicutes,4HIXF@91061|Bacilli,275IW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
GZD3_k127_581688_4	1499967.BAYZ01000164_gene6679	9.186e-59	210.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	uma2	-	-	-	-	-	-	-	-	-	-	-	Uma2
GZD3_k127_581688_1	479434.Sthe_1837	1.755e-87	304.0	COG1085@1|root,COG1085@2|Bacteria,2G848@200795|Chloroflexi,27XWY@189775|Thermomicrobia	189775|Thermomicrobia	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_581688_0	485913.Krac_6661	1.822e-203	650.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
GZD3_k127_581688_2	1382306.JNIM01000001_gene1049	2.282e-82	280.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
GZD3_k127_581688_3	1382306.JNIM01000001_gene1048	1.264e-68	235.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	pcmD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
GZD3_k127_5819078_0	485913.Krac_0472	3.675e-56	207.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	aadD	-	-	ko:K17882	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	KNTase_C,NTP_transf_2
GZD3_k127_5819078_1	1120949.KB903295_gene2534	1.263e-14	77.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5831831_1	338969.Rfer_0358	2.598e-64	229.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_5831831_0	485913.Krac_3080	1.053e-132	428.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
GZD3_k127_5841890_0	1035308.AQYY01000001_gene3289	1.985e-117	392.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,24BEP@186801|Clostridia,262IK@186807|Peptococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
GZD3_k127_5841890_6	1108045.GORHZ_134_00040	1.188e-39	157.0	2DM5A@1|root,31SBV@2|Bacteria,2IPT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5841890_10	5465.ENH81268	1.442e-10	73.0	COG0596@1|root,2QPPY@2759|Eukaryota,38J2J@33154|Opisthokonta,3NZP5@4751|Fungi,3QUN9@4890|Ascomycota,21A6B@147550|Sordariomycetes,1EZSW@1028384|Glomerellales	4751|Fungi	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
GZD3_k127_5841890_4	1089553.Tph_c21870	1.781e-41	167.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
GZD3_k127_5841890_1	1240349.ANGC01000038_gene3193	2.138e-83	296.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
GZD3_k127_5841890_7	1385519.N801_19715	8.985e-18	92.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4FGHD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5841890_3	309801.trd_A0831	3.417e-42	158.0	COG0640@1|root,COG0640@2|Bacteria,2GA4N@200795|Chloroflexi,27Z88@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
GZD3_k127_5841890_2	1382306.JNIM01000001_gene3598	4.797e-46	171.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
GZD3_k127_5841890_5	926569.ANT_12060	5.152e-41	158.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
GZD3_k127_5841890_9	383372.Rcas_4192	3.464e-12	70.0	2A4IN@1|root,30T57@2|Bacteria,2GB1H@200795|Chloroflexi,377QX@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
GZD3_k127_5841890_8	1382306.JNIM01000001_gene2207	8.574e-16	77.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD3_k127_5849449_2	164757.Mjls_4613	1.347e-34	143.0	COG0682@1|root,COG0682@2|Bacteria,2GP8C@201174|Actinobacteria,235FI@1762|Mycobacteriaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
GZD3_k127_5849449_0	1382306.JNIM01000001_gene385	4.414e-82	278.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
GZD3_k127_5849449_1	485913.Krac_8326	4.96e-48	178.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
GZD3_k127_5849449_3	309799.DICTH_0672	4.347e-20	92.0	COG0441@1|root,COG0441@2|Bacteria	2|Bacteria	J	threonyl-tRNA aminoacylation	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
GZD3_k127_5849947_0	1089544.KB912942_gene3315	1.241e-99	361.0	COG1404@1|root,COG4934@1|root,COG1404@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M10,SLH
GZD3_k127_5849947_1	1380370.JIBA01000015_gene100	3.123e-08	68.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4FJVF@85021|Intrasporangiaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
GZD3_k127_5854549_3	552811.Dehly_1398	6.779e-29	122.0	COG1309@1|root,COG1309@2|Bacteria,2G72N@200795|Chloroflexi,34DFE@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
GZD3_k127_5854549_1	1382306.JNIM01000001_gene3372	3.67e-87	297.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_5854549_2	882083.SacmaDRAFT_2314	5.436e-39	151.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4E6B1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
GZD3_k127_5854549_0	485913.Krac_8399	6.535e-93	317.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
GZD3_k127_5854549_5	1121022.ABENE_17155	0.0001084	52.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,2TUNQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_5880912_0	1128421.JAGA01000004_gene2484	3.564e-103	346.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
GZD3_k127_5880912_3	323259.Mhun_0913	7.921e-13	79.0	COG0457@1|root,arCOG03032@2157|Archaea,2Y7M7@28890|Euryarchaeota	28890|Euryarchaeota	S	COG0457 FOG TPR repeat	tpr	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_2,TPR_8
GZD3_k127_5880912_2	266117.Rxyl_0142	2.012e-34	139.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
GZD3_k127_5880912_1	485913.Krac_6814	2.212e-76	272.0	COG0793@1|root,COG0793@2|Bacteria,2G6A8@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
GZD3_k127_5895548_0	1121033.AUCF01000032_gene2634	4.491e-105	349.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,2JPU7@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0119 Isopropylmalate homocitrate citramalate synthases	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
GZD3_k127_5895548_1	1382306.JNIM01000001_gene1940	2.197e-27	127.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
GZD3_k127_5897742_3	1173028.ANKO01000106_gene307	6.71e-44	174.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_2,TPR_8
GZD3_k127_5897742_2	1128421.JAGA01000002_gene1835	8.015e-73	252.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
GZD3_k127_5897742_0	1280390.CBQR020000086_gene1885	1.783e-110	371.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,26V3Z@186822|Paenibacillaceae	91061|Bacilli	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
GZD3_k127_5897742_1	1382306.JNIM01000001_gene2021	1.794e-88	297.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
GZD3_k127_5917272_15	1382306.JNIM01000001_gene377	2.651e-13	72.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
GZD3_k127_5917272_3	485913.Krac_8335	8.974e-120	396.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
GZD3_k127_5917272_16	1540221.JQNI01000002_gene1938	4.97e-11	70.0	2EMYS@1|root,33FKY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
GZD3_k127_5917272_17	240292.Ava_1938	1.502e-05	48.0	COG1598@1|root,COG1598@2|Bacteria,1GAQW@1117|Cyanobacteria,1HPWK@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5917272_18	313612.L8106_26952	4.39e-05	46.0	COG1598@1|root,COG1598@2|Bacteria,1GAQW@1117|Cyanobacteria,1HDWP@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5917272_6	1382306.JNIM01000001_gene3843	5.923e-102	341.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
GZD3_k127_5917272_1	1382306.JNIM01000001_gene3374	5.714e-143	475.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi	200795|Chloroflexi	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
GZD3_k127_5917272_5	485913.Krac_2295	2.359e-105	357.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5917272_9	1499967.BAYZ01000119_gene3173	4.295e-55	203.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD3_k127_5917272_10	931627.MycrhDRAFT_1246	5.332e-54	204.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,2339V@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_5917272_14	1304865.JAGF01000001_gene960	5.986e-34	138.0	COG0454@1|root,COG0645@1|root,COG0456@2|Bacteria,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,Acetyltransf_1,CPT
GZD3_k127_5917272_2	485913.Krac_1076	4.913e-138	447.0	COG2207@1|root,COG2207@2|Bacteria,2G5J1@200795|Chloroflexi	200795|Chloroflexi	K	helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
GZD3_k127_5917272_11	1089545.KB913037_gene1841	2.301e-46	170.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4E71U@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
GZD3_k127_5917272_0	526225.Gobs_2100	1.461e-171	543.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4ETNI@85013|Frankiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GZD3_k127_5917272_12	479432.Sros_3626	1.276e-45	168.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria,4EKGQ@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
GZD3_k127_5917272_13	1214242.B446_29190	5.541e-36	145.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD3_k127_5917272_8	1283299.AUKG01000001_gene2149	7.568e-59	213.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4CQ50@84995|Rubrobacteria	84995|Rubrobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
GZD3_k127_5917272_4	485913.Krac_2379	8.517e-118	400.0	COG0642@1|root,COG2205@2|Bacteria,2G5YT@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
GZD3_k127_5917272_7	1382306.JNIM01000001_gene2511	1.881e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,2G652@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_591799_1	485913.Krac_8785	1.005e-180	577.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
GZD3_k127_591799_0	1382306.JNIM01000001_gene77	1.124e-241	754.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
GZD3_k127_591799_2	1382306.JNIM01000001_gene3404	6.948e-08	54.0	COG1432@1|root,COG1432@2|Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
GZD3_k127_5934340_8	335543.Sfum_2055	0.0005763	44.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,42SXD@68525|delta/epsilon subdivisions,2WP1U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
GZD3_k127_5934340_7	1043205.AFYF01000099_gene627	3.018e-07	56.0	COG4422@1|root,COG4422@2|Bacteria,2I55Q@201174|Actinobacteria,4FIQS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5934340_2	1123060.JONP01000063_gene3848	3.599e-45	167.0	COG3293@1|root,COG3293@2|Bacteria,1RJDY@1224|Proteobacteria,2UJBD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
GZD3_k127_5934340_1	1121106.JQKB01000245_gene5099	4.492e-54	197.0	COG3293@1|root,COG3293@2|Bacteria,1REUV@1224|Proteobacteria,2VBIA@28211|Alphaproteobacteria,2JWR1@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
GZD3_k127_5934340_5	319003.Bra1253DRAFT_00419	9.859e-19	94.0	28SWP@1|root,2ZF66@2|Bacteria,1PAGU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5934340_6	368408.Tpen_1406	7.527e-12	78.0	arCOG09752@1|root,arCOG09752@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_5934340_3	1419583.V466_18780	3.118e-43	160.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,1YRVR@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	Helix-turn-helix domain of resolvase	tnpR	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
GZD3_k127_5934340_0	272134.KB731325_gene510	2.13e-87	302.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria,1HGQD@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
GZD3_k127_5934340_4	329726.AM1_3696	2.403e-21	96.0	COG2963@1|root,COG2963@2|Bacteria,1GAKB@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
GZD3_k127_5957688_1	926569.ANT_04800	1.854e-124	404.0	COG2513@1|root,COG2513@2|Bacteria,2G6M0@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
GZD3_k127_5957688_0	1268237.G114_09975	1.752e-205	650.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1Y5JH@135624|Aeromonadales	135624|Aeromonadales	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
GZD3_k127_5957688_5	485913.Krac_8639	8.176e-31	135.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
GZD3_k127_5957688_6	68223.JNZY01000003_gene4700	1.364e-06	57.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GZD3_k127_5957688_4	1382306.JNIM01000001_gene373	6.747e-41	168.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
GZD3_k127_5957688_3	485913.Krac_10209	4.09e-57	214.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
GZD3_k127_5957688_2	1382306.JNIM01000001_gene375	4.302e-81	298.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi	200795|Chloroflexi	P	PFAM copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
GZD3_k127_596927_1	1411123.JQNH01000001_gene1374	1.42e-47	178.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,2U3M8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
GZD3_k127_596927_0	485913.Krac_12478	3.597e-192	619.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
GZD3_k127_596927_2	93220.LV28_01620	4.619e-27	111.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,2VX6M@28216|Betaproteobacteria,1KA9D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cation transport regulator	-	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
GZD3_k127_6018079_0	485913.Krac_12228	2.016e-157	514.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
GZD3_k127_6018180_0	1382306.JNIM01000001_gene243	1.449e-313	983.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
GZD3_k127_6018180_1	1227454.C446_09730	1.358e-59	235.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
GZD3_k127_6018180_2	1382306.JNIM01000001_gene2506	1.959e-55	212.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
GZD3_k127_6018628_1	485913.Krac_10794	1.518e-232	732.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
GZD3_k127_6018628_7	485913.Krac_10950	1.424e-30	131.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_10950|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_6018628_9	1382306.JNIM01000001_gene1270	5.51e-18	89.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Response_reg
GZD3_k127_6018628_6	1382306.JNIM01000001_gene2931	6.905e-49	194.0	COG0642@1|root,COG2205@2|Bacteria,2G8UJ@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GZD3_k127_6018628_0	1382306.JNIM01000001_gene2540	8.196e-304	950.0	COG2183@1|root,COG2183@2|Bacteria,2G66S@200795|Chloroflexi	200795|Chloroflexi	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
GZD3_k127_6018628_5	1382306.JNIM01000001_gene843	7.208e-95	322.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_6018628_8	1356852.N008_01765	9.945e-19	100.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
GZD3_k127_6018628_10	710696.Intca_1872	4.541e-06	57.0	COG0526@1|root,COG0526@2|Bacteria,2IS1E@201174|Actinobacteria,4FJ5Y@85021|Intrasporangiaceae	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
GZD3_k127_6018628_2	1128421.JAGA01000003_gene3419	1.024e-110	365.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_6018628_4	1123248.KB893314_gene3621	7.103e-105	360.0	COG0387@1|root,COG0387@2|Bacteria,4P224@976|Bacteroidetes	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
GZD3_k127_6018628_3	1242864.D187_000842	9.584e-110	369.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2YY3U@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
GZD3_k127_6020122_1	1323361.JPOC01000066_gene106	9.841e-123	416.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4FV8C@85025|Nocardiaceae	201174|Actinobacteria	I	AMP-binding enzyme	fadD11_1	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
GZD3_k127_6020122_2	1304874.JAFY01000002_gene150	1.011e-120	398.0	COG1814@1|root,COG1814@2|Bacteria,3TBXB@508458|Synergistetes	508458|Synergistetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
GZD3_k127_6020122_0	395961.Cyan7425_4133	8.051e-219	706.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,3KGUQ@43988|Cyanothece	1117|Cyanobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2,3.6.3.8	ko:K01531,ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23,3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
GZD3_k127_6020122_3	485913.Krac_7240	2.55e-52	199.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
GZD3_k127_6020122_5	1121015.N789_05975	1.284e-31	135.0	2DU7K@1|root,33P8K@2|Bacteria,1P4QZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_6020122_7	536227.CcarbDRAFT_0448	4.502e-25	119.0	COG1835@1|root,COG1835@2|Bacteria,1V7CG@1239|Firmicutes,25FV5@186801|Clostridia,36FTD@31979|Clostridiaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GZD3_k127_6020122_4	1183438.GKIL_3603	1.169e-49	194.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
GZD3_k127_6020122_6	765912.Thimo_0882	6.741e-27	128.0	COG1073@1|root,COG1073@2|Bacteria,1N8YB@1224|Proteobacteria,1RXY9@1236|Gammaproteobacteria,1WXE1@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD3_k127_6020122_8	926569.ANT_04440	3.024e-14	85.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
GZD3_k127_6022026_3	106370.Francci3_3505	0.0009813	53.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigB	GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
GZD3_k127_6022026_2	338963.Pcar_0295	0.0001887	56.0	COG3440@1|root,COG3440@2|Bacteria,1NE0N@1224|Proteobacteria,42RDP@68525|delta/epsilon subdivisions,2WMZC@28221|Deltaproteobacteria,43TG8@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
GZD3_k127_6022026_0	485913.Krac_0167	5.069e-20	97.0	COG3415@1|root,COG3415@2|Bacteria,2G9PU@200795|Chloroflexi	2|Bacteria	L	InterPro IPR009057	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
GZD3_k127_6022026_1	1123508.JH636439_gene320	5.545e-07	54.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_33
GZD3_k127_60292_1	471852.Tcur_0151	1.754e-28	116.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4EJ3D@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_6029301_1	329726.AM1_3617	3.96e-96	338.0	COG3882@1|root,COG3882@2|Bacteria,1G2GR@1117|Cyanobacteria	1117|Cyanobacteria	Q	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	NIF,PP-binding
GZD3_k127_6029301_5	1382306.JNIM01000001_gene1497	9.24e-54	196.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
GZD3_k127_6029301_0	1382306.JNIM01000001_gene2995	1.065e-223	713.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5,4.2.2.6	ko:K01730,ko:K10804	ko00040,ko01040,map00040,map01040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000,ko01004	-	-	-	CBM_35,FR47,Glyco_hydro_88,Lipase_GDSL_2
GZD3_k127_6029301_2	485913.Krac_7764	7.947e-92	310.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_7764|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_6029301_8	1382306.JNIM01000001_gene2653	2.52e-42	160.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
GZD3_k127_6029301_4	189753.AXAS01000073_gene7666	5.677e-86	287.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2TT20@28211|Alphaproteobacteria,3K65Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	comD	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
GZD3_k127_6029301_3	189753.AXAS01000073_gene7665	2.603e-91	303.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TVWE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
GZD3_k127_6029301_7	1120950.KB892768_gene5320	4.019e-47	178.0	COG1670@1|root,COG1670@2|Bacteria,2I4GW@201174|Actinobacteria,4DVCC@85009|Propionibacteriales	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
GZD3_k127_6029301_6	1382356.JQMP01000003_gene1854	3.298e-48	184.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	189775|Thermomicrobia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
GZD3_k127_6029883_3	864069.MicloDRAFT_00002920	9.328e-56	201.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
GZD3_k127_6029883_1	864069.MicloDRAFT_00002930	6.991e-84	284.0	COG3335@1|root,COG3335@2|Bacteria,1MXYQ@1224|Proteobacteria,2TSX4@28211|Alphaproteobacteria,1JYEX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
GZD3_k127_6029883_4	2342.SOPEG_4002	0.0002371	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
GZD3_k127_6029883_0	1382306.JNIM01000001_gene3874	6.094e-141	465.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
GZD3_k127_6029883_2	485913.Krac_8006	5.719e-67	235.0	COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
GZD3_k127_6031597_0	926550.CLDAP_39650	1.116e-101	346.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
GZD3_k127_6033137_1	485913.Krac_2570	1.386e-75	257.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
GZD3_k127_6033137_9	1223543.GP2_003_01380	4.779e-17	86.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GBT5@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_6033137_0	479434.Sthe_0072	1.013e-105	379.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
GZD3_k127_6033137_10	1380356.JNIK01000015_gene2351	2.055e-07	54.0	COG0531@1|root,COG0531@2|Bacteria,2IDWU@201174|Actinobacteria	201174|Actinobacteria	E	Amino acid permease	potE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
GZD3_k127_6033137_2	485913.Krac_10872	1.336e-49	201.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9
GZD3_k127_6033137_8	1172188.KB911823_gene686	1.357e-18	95.0	2BF47@1|root,328WE@2|Bacteria,2IM74@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
GZD3_k127_6033137_3	485913.Krac_0782	6.068e-41	169.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
GZD3_k127_6033137_4	1121272.KB903259_gene6524	7.102e-38	153.0	COG3247@1|root,COG3247@2|Bacteria,2ISIY@201174|Actinobacteria,4DMAA@85008|Micromonosporales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
GZD3_k127_6033137_5	675635.Psed_5891	1.057e-31	134.0	29VND@1|root,33797@2|Bacteria,2I845@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_6033137_7	1380393.JHVP01000006_gene3982	1.062e-20	92.0	COG4894@1|root,COG4894@2|Bacteria,2GKWI@201174|Actinobacteria,4EVVT@85013|Frankiales	201174|Actinobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
GZD3_k127_6046265_2	485913.Krac_10860	3.289e-41	160.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
GZD3_k127_6046265_7	1254432.SCE1572_30885	9.256e-08	58.0	COG1403@1|root,COG1403@2|Bacteria,1P9ZG@1224|Proteobacteria,43835@68525|delta/epsilon subdivisions,2X9VY@28221|Deltaproteobacteria,2YVHD@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
GZD3_k127_6046265_9	1209072.ALBT01000012_gene3425	0.0002837	50.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,1FGUG@10|Cellvibrio	1236|Gammaproteobacteria	S	dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
GZD3_k127_6046265_1	1382306.JNIM01000001_gene3493	2.58e-46	175.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
GZD3_k127_6046265_6	1382306.JNIM01000001_gene3494	1.049e-18	98.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K03886	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00151,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
GZD3_k127_6046265_0	1382306.JNIM01000001_gene1295	1.048e-108	369.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
GZD3_k127_6046265_3	485913.Krac_8194	3.391e-36	140.0	COG2151@1|root,COG2151@2|Bacteria,2G75C@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
GZD3_k127_6046265_4	338963.Pcar_1499	3.027e-32	133.0	COG1443@1|root,COG1443@2|Bacteria,1P8AM@1224|Proteobacteria,42T9Z@68525|delta/epsilon subdivisions,2WP8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_6046265_8	761193.Runsl_2083	8.947e-05	56.0	COG3942@1|root,COG3942@2|Bacteria,4NKM5@976|Bacteroidetes,47X2F@768503|Cytophagia	976|Bacteroidetes	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
GZD3_k127_6046265_5	1304874.JAFY01000002_gene410	4.124e-19	97.0	COG0561@1|root,COG0561@2|Bacteria,3TB3P@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
GZD3_k127_6060314_0	1382306.JNIM01000001_gene68	2.313e-16	85.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene68|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_710704_0	318996.AXAZ01000005_gene159	3.329e-05	58.0	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,2TU0B@28211|Alphaproteobacteria,3JSPQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
GZD3_k127_730259_0	1382306.JNIM01000001_gene522	3.39e-105	353.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_730259_1	1382306.JNIM01000001_gene1392	4.173e-47	186.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
GZD3_k127_745272_0	485913.Krac_10258	8.012e-230	730.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
GZD3_k127_745272_7	251221.35210879	8.302e-05	54.0	COG5464@1|root,COG5464@2|Bacteria,1GDVP@1117|Cyanobacteria	1117|Cyanobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_745272_6	1121945.ATXS01000001_gene2200	1.261e-06	59.0	COG0558@1|root,arCOG00672@2157|Archaea,2Y3T3@28890|Euryarchaeota,23ZMD@183963|Halobacteria	183963|Halobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
GZD3_k127_745272_5	195250.CM001776_gene717	3.801e-08	58.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1GZWS@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
GZD3_k127_745272_2	1382306.JNIM01000001_gene175	6.312e-57	211.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
GZD3_k127_745272_1	479434.Sthe_0812	3.564e-96	336.0	COG1512@1|root,COG1512@2|Bacteria,2G7EX@200795|Chloroflexi,27YYD@189775|Thermomicrobia	2|Bacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	DUF2207,TPM_phosphatase
GZD3_k127_745272_3	1122182.KB903825_gene328	5.404e-29	127.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
GZD3_k127_745272_4	670307.HYPDE_40378	5.453e-21	95.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2U7G6@28211|Alphaproteobacteria,3N8FM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
GZD3_k127_757881_4	1033730.CAHG01000014_gene1855	1.023e-25	113.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DPKG@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
GZD3_k127_757881_5	306281.AJLK01000152_gene2099	8.028e-22	104.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_757881_6	1283283.ATXA01000001_gene363	3.873e-08	55.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
GZD3_k127_757881_2	215803.DB30_8587	8.586e-82	278.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,2YV2X@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
GZD3_k127_757881_1	215803.DB30_0441	5.278e-117	390.0	COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
GZD3_k127_757881_0	234267.Acid_5058	7.334e-174	559.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	-	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
GZD3_k127_757881_3	118166.JH976537_gene4051	1.311e-60	214.0	COG4894@1|root,COG4894@2|Bacteria,1GEPD@1117|Cyanobacteria	1117|Cyanobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
GZD3_k127_759060_1	485913.Krac_1559	1.743e-64	229.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
GZD3_k127_759060_0	653045.Strvi_6126	1.13e-69	245.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
GZD3_k127_760670_6	102232.GLO73106DRAFT_00035380	1.907e-67	238.0	COG2253@1|root,COG2253@2|Bacteria,1GBWG@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD3_k127_760670_0	163908.KB235896_gene4971	0.0	1135.0	COG5635@1|root,COG5635@2|Bacteria,1G80T@1117|Cyanobacteria	1117|Cyanobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_760670_10	1235794.C811_00953	4.531e-25	121.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CUWF@84998|Coriobacteriia	84998|Coriobacteriia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
GZD3_k127_760670_5	335543.Sfum_2055	1.779e-73	252.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,42SXD@68525|delta/epsilon subdivisions,2WP1U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
GZD3_k127_760670_4	1206739.BAGJ01000274_gene3883	1.432e-89	298.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria,4G5U8@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_760670_2	1077972.ARGLB_058_00070	1.385e-97	322.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,1WA3E@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
GZD3_k127_760670_1	211114.JOEF01000031_gene1889	2.158e-119	400.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4E2UF@85010|Pseudonocardiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
GZD3_k127_760670_9	1237500.ANBA01000002_gene6107	3.426e-28	118.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
GZD3_k127_760670_7	358823.DF19_35315	5.517e-55	197.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
GZD3_k127_760670_8	251221.35213232	3.242e-37	143.0	COG2253@1|root,COG2253@2|Bacteria,1GBWG@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
GZD3_k127_76196_7	1380394.JADL01000013_gene774	2.615e-50	196.0	COG3447@1|root,COG4564@1|root,COG3447@2|Bacteria,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,2JZ0H@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
GZD3_k127_76196_6	1382306.JNIM01000001_gene255	9.5e-54	205.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
GZD3_k127_76196_13	1242864.D187_005281	2.738e-06	58.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
GZD3_k127_76196_11	512565.AMIS_17890	5.086e-11	69.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4DFMD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_76196_14	685727.REQ_16190	3.098e-06	58.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4G39Q@85025|Nocardiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
GZD3_k127_76196_10	479434.Sthe_1265	9.103e-28	117.0	COG4803@1|root,COG4803@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_76196_8	388467.A19Y_1746	1.725e-47	178.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria,1HB6E@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_76196_9	1120949.KB903328_gene8808	5.652e-28	124.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria,4DKUX@85008|Micromonosporales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GZD3_k127_76196_1	1382306.JNIM01000001_gene574	6.591e-158	513.0	COG1502@1|root,COG1502@2|Bacteria,2G7KK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
GZD3_k127_76196_12	251221.35211431	1.546e-07	61.0	2EAFX@1|root,334J9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_76196_5	235985.BBPN01000035_gene821	1.596e-63	237.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,2NM4U@228398|Streptacidiphilus	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
GZD3_k127_76196_3	368407.Memar_2102	1.161e-118	401.0	COG0038@1|root,arCOG02569@2157|Archaea,2Y26D@28890|Euryarchaeota	28890|Euryarchaeota	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
GZD3_k127_76196_4	867903.ThesuDRAFT_01805	1.279e-70	256.0	COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,24YZ7@186801|Clostridia	186801|Clostridia	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
GZD3_k127_76196_2	485913.Krac_11231	3.292e-135	446.0	COG1271@1|root,COG1271@2|Bacteria,2G63Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
GZD3_k127_76196_0	234267.Acid_7578	1.408e-182	577.0	COG2303@1|root,COG2303@2|Bacteria,3Y456@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
GZD3_k127_763321_0	485913.Krac_8263	5.745e-73	251.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
GZD3_k127_763321_2	485913.Krac_10805	1.379e-29	129.0	COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
GZD3_k127_767886_0	479434.Sthe_2434	1.588e-206	665.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia	189775|Thermomicrobia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
GZD3_k127_767886_3	485913.Krac_4380	9.072e-43	166.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
GZD3_k127_767886_5	693979.Bache_1014	2.652e-12	73.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
GZD3_k127_767886_4	485913.Krac_10950	2.226e-29	122.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_10950|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_767886_2	1382306.JNIM01000001_gene2931	3.034e-44	179.0	COG0642@1|root,COG2205@2|Bacteria,2G8UJ@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
GZD3_k127_767886_1	644283.Micau_4289	3.384e-57	222.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4DATU@85008|Micromonosporales	201174|Actinobacteria	I	Squalene-hopene cyclase C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
GZD3_k127_771749_2	562970.Btus_1657	3.12e-34	144.0	2C5SG@1|root,2ZP0Z@2|Bacteria,1V7HA@1239|Firmicutes,4IJKK@91061|Bacilli,27ACR@186823|Alicyclobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_771749_3	1120972.AUMH01000014_gene2576	5.312e-15	85.0	2EHVU@1|root,30CAH@2|Bacteria,1U9GY@1239|Firmicutes,4IJKZ@91061|Bacilli,27AN0@186823|Alicyclobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_771749_0	562970.Btus_1655	0.0	1900.0	COG5013@1|root,COG5013@2|Bacteria,1TQG1@1239|Firmicutes,4HBVB@91061|Bacilli,279MD@186823|Alicyclobacillaceae	91061|Bacilli	C	Molybdopterin oxidoreductase Fe4S4 domain	narG	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
GZD3_k127_771749_1	1123405.AUMM01000023_gene1974	4.656e-195	614.0	COG1140@1|root,COG1140@2|Bacteria,1TRGG@1239|Firmicutes,4HAR2@91061|Bacilli	91061|Bacilli	C	Nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
GZD3_k127_774764_1	1382356.JQMP01000003_gene1489	3.235e-152	494.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
GZD3_k127_774764_0	1120972.AUMH01000001_gene1105	8.787e-318	1003.0	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,279I7@186823|Alicyclobacillaceae	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
GZD3_k127_774764_4	420324.KI911943_gene5229	1.734e-18	97.0	COG2823@1|root,COG2823@2|Bacteria,1N1R4@1224|Proteobacteria,2UDII@28211|Alphaproteobacteria	1224|Proteobacteria	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_774764_2	926554.KI912652_gene4083	5.027e-21	106.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_774764_3	1353531.AZNX01000006_gene5415	4.311e-19	96.0	COG2823@1|root,COG2823@2|Bacteria,1N1R4@1224|Proteobacteria,2UDII@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
GZD3_k127_791810_0	485913.Krac_8508	3.372e-235	738.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
GZD3_k127_791810_3	1382306.JNIM01000001_gene3502	8.526e-35	143.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GZD3_k127_791810_2	1382306.JNIM01000001_gene2834	1.553e-36	145.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
GZD3_k127_791810_4	485913.Krac_11311	9.373e-34	143.0	COG1073@1|root,COG1073@2|Bacteria,2G73I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
GZD3_k127_791810_1	485913.Krac_11307	3.793e-80	276.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
GZD3_k127_79798_13	485913.Krac_4773	2.099e-45	185.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_79798_10	266117.Rxyl_1999	3.765e-70	248.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4CQHH@84995|Rubrobacteria	84995|Rubrobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
GZD3_k127_79798_4	438753.AZC_2758	4.624e-110	367.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2TQQK@28211|Alphaproteobacteria,3F062@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	MA20_17390	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
GZD3_k127_79798_2	1237149.C900_00699	4.252e-170	559.0	COG3408@1|root,COG3408@2|Bacteria,4NK6K@976|Bacteroidetes,47TNN@768503|Cytophagia	976|Bacteroidetes	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
GZD3_k127_79798_11	1382306.JNIM01000001_gene2771	2.03e-49	195.0	COG0515@1|root,COG1840@1|root,COG0515@2|Bacteria,COG1840@2|Bacteria,2G850@200795|Chloroflexi	2|Bacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,SBP_bac_6
GZD3_k127_79798_14	1183438.GKIL_3248	3.224e-05	57.0	COG5464@1|root,COG5464@2|Bacteria,1GDVP@1117|Cyanobacteria	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
GZD3_k127_79798_6	485913.Krac_8937	1.894e-83	291.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
GZD3_k127_79798_7	485913.Krac_9017	1.11e-75	270.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD3_k127_79798_5	1382306.JNIM01000001_gene4116	4.228e-104	347.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
GZD3_k127_79798_1	485913.Krac_9015	5.652e-215	678.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
GZD3_k127_79798_15	383372.Rcas_1961	7.189e-05	53.0	2DQVM@1|root,338Y0@2|Bacteria,2G9DI@200795|Chloroflexi,3776N@32061|Chloroflexia	32061|Chloroflexia	S	LppX_LprAFG lipoprotein	-	-	-	ko:K14954	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
GZD3_k127_79798_3	485913.Krac_8738	9.002e-121	408.0	COG0477@1|root,COG2814@2|Bacteria,2G7PR@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_79798_8	512565.AMIS_57740	1.539e-74	260.0	COG2267@1|root,COG2267@2|Bacteria,2IFK6@201174|Actinobacteria,4DD5A@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
GZD3_k127_79798_12	485913.Krac_8952	1.746e-48	197.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	XK27_10720	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
GZD3_k127_79798_0	1382306.JNIM01000001_gene4207	0.0	1128.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
GZD3_k127_809619_0	1382306.JNIM01000001_gene4085	6.673e-35	136.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
GZD3_k127_809619_1	1227261.HMPREF0043_01813	0.0002446	53.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2IBV1@201174|Actinobacteria,4D5P3@85005|Actinomycetales	201174|Actinobacteria	M	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
GZD3_k127_81389_1	525904.Tter_0973	3.12e-113	372.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	ugpC	-	-	ko:K10112,ko:K10195	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00202,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	iJN678.ggtA	ABC_tran,TOBE,TOBE_2
GZD3_k127_81389_0	1382306.JNIM01000001_gene3643	4.29e-182	580.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
GZD3_k127_81389_3	926564.KI911686_gene5469	1.308e-93	316.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
GZD3_k127_81389_2	485913.Krac_11436	6.551e-98	332.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
GZD3_k127_81389_4	1089545.KB913037_gene9199	1.756e-12	72.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4E1FP@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
GZD3_k127_815997_3	1382306.JNIM01000001_gene1339	4.164e-76	265.0	COG0750@1|root,COG0750@2|Bacteria,2G6HV@200795|Chloroflexi	200795|Chloroflexi	M	TIGRFAM membrane-associated zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
GZD3_k127_815997_0	485913.Krac_7773	4.527e-181	577.0	COG0821@1|root,COG0821@2|Bacteria,2G5SC@200795|Chloroflexi	200795|Chloroflexi	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
GZD3_k127_815997_9	1177928.TH2_04323	1.554e-05	57.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,2JQUH@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
GZD3_k127_815997_1	204669.Acid345_2243	5.706e-154	499.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD3_k127_815997_2	1128421.JAGA01000002_gene1219	2.89e-116	383.0	COG1052@1|root,COG1052@2|Bacteria,2NNZP@2323|unclassified Bacteria	2|Bacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
GZD3_k127_815997_4	1242864.D187_005937	6.791e-62	222.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
GZD3_k127_815997_7	243233.MCA2812	1.264e-24	109.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,1SCE7@1236|Gammaproteobacteria,1XFBK@135618|Methylococcales	135618|Methylococcales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
GZD3_k127_815997_6	1287116.X734_22235	8.332e-29	121.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
GZD3_k127_815997_8	1123368.AUIS01000008_gene2271	5.896e-06	56.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
GZD3_k127_815997_5	485913.Krac_11181	6.11e-31	135.0	COG0457@1|root,COG0457@2|Bacteria	485913.Krac_11181|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_816507_0	1382306.JNIM01000001_gene264	1.774e-124	404.0	COG3396@1|root,COG3396@2|Bacteria,2G9AI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
GZD3_k127_816507_4	1463825.JNXC01000032_gene1728	1.137e-16	92.0	COG1413@1|root,COG1413@2|Bacteria,2GKP6@201174|Actinobacteria,4E7HW@85010|Pseudonocardiales	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
GZD3_k127_816507_3	1128421.JAGA01000002_gene129	1.379e-53	196.0	COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria	2|Bacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
GZD3_k127_816507_1	485913.Krac_11346	3.109e-109	355.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
GZD3_k127_816507_2	1382306.JNIM01000001_gene1297	7.437e-105	349.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
GZD3_k127_82744_2	479434.Sthe_2179	2.642e-79	270.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi,27XY4@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_82744_3	1382306.JNIM01000001_gene838	2.776e-73	256.0	COG0842@1|root,COG0842@2|Bacteria,2G8GV@200795|Chloroflexi	200795|Chloroflexi	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
GZD3_k127_82744_5	1382356.JQMP01000004_gene311	2.328e-14	78.0	COG2261@1|root,COG2261@2|Bacteria,2G9IU@200795|Chloroflexi,27Z91@189775|Thermomicrobia	189775|Thermomicrobia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
GZD3_k127_82744_4	1111479.AXAR01000002_gene1839	2.683e-72	248.0	COG1335@1|root,COG1335@2|Bacteria,1U4IN@1239|Firmicutes,4HE4U@91061|Bacilli	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
GZD3_k127_82744_0	485913.Krac_4166	2.685e-144	464.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
GZD3_k127_82744_1	1382306.JNIM01000001_gene4175	3.319e-94	314.0	COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi	200795|Chloroflexi	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sod	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
GZD3_k127_835570_2	1120934.KB894427_gene1048	5.152e-70	253.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4E1NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	naringenin-chalcone synthase	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
GZD3_k127_835570_0	1118054.CAGW01000009_gene3932	9.722e-199	631.0	COG0112@1|root,COG0112@2|Bacteria,1V14Z@1239|Firmicutes,4HF9D@91061|Bacilli	91061|Bacilli	E	Serine hydroxymethyltransferase	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
GZD3_k127_835570_3	1444309.JAQG01000090_gene1220	4.28e-59	212.0	COG1802@1|root,COG1802@2|Bacteria,1V3VV@1239|Firmicutes,4HI43@91061|Bacilli,26XU5@186822|Paenibacillaceae	91061|Bacilli	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
GZD3_k127_835570_1	1382306.JNIM01000001_gene4091	2.164e-142	464.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
GZD3_k127_835570_8	1121946.AUAX01000011_gene3912	9.016e-11	75.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DGW5@85008|Micromonosporales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
GZD3_k127_835570_5	485913.Krac_9801	1.026e-40	172.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
GZD3_k127_835570_9	446462.Amir_5476	3.71e-10	74.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E0PQ@85010|Pseudonocardiales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_12
GZD3_k127_835570_6	1172188.KB911834_gene4138	6.323e-37	162.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
GZD3_k127_835570_7	383372.Rcas_0197	1.272e-19	105.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi,37581@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
GZD3_k127_835570_4	1121377.KB906401_gene3435	2.216e-41	162.0	COG1708@1|root,COG1708@2|Bacteria,1WMKX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4111)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111
GZD3_k127_836750_4	1163407.UU7_03702	0.0002922	49.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1X4WI@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
GZD3_k127_836750_1	1128421.JAGA01000001_gene2435	3.056e-116	385.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
GZD3_k127_836750_3	197221.22295380	3.978e-20	98.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
GZD3_k127_836750_2	1443125.Z962_07700	3.976e-31	138.0	COG4974@1|root,COG4974@2|Bacteria,1UTX8@1239|Firmicutes,24DFG@186801|Clostridia,36E3B@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
GZD3_k127_836750_0	1382306.JNIM01000001_gene3924	3.2e-192	608.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
GZD3_k127_837278_0	251221.35210711	4.391e-191	610.0	COG3039@1|root,COG3039@2|Bacteria,1G52R@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
GZD3_k127_837282_0	1382306.JNIM01000001_gene3950	2.868e-136	456.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
GZD3_k127_85464_0	316274.Haur_3072	1.572e-86	305.0	COG2124@1|root,COG2124@2|Bacteria,2G83S@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
GZD3_k127_85464_3	204669.Acid345_1680	4.753e-09	60.0	COG2128@1|root,COG2128@2|Bacteria,3Y8NV@57723|Acidobacteria,2JNMP@204432|Acidobacteriia	204432|Acidobacteriia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_85464_2	240015.ACP_0434	2.296e-09	62.0	COG2128@1|root,COG2128@2|Bacteria,3Y8B3@57723|Acidobacteria,2JNC0@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
GZD3_k127_85464_1	1379698.RBG1_1C00001G1377	2.339e-45	183.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
GZD3_k127_863508_2	767817.Desgi_4458	5.881e-53	194.0	COG0500@1|root,COG0500@2|Bacteria,1UTAX@1239|Firmicutes,2527A@186801|Clostridia	186801|Clostridia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_863508_1	357808.RoseRS_2395	5.833e-88	302.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
GZD3_k127_863508_4	1121406.JAEX01000001_gene92	1.392e-20	105.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42MC8@68525|delta/epsilon subdivisions,2WPR0@28221|Deltaproteobacteria,2MBRZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
GZD3_k127_863508_3	266117.Rxyl_1417	1.604e-31	125.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
GZD3_k127_863508_0	485913.Krac_9213	2.698e-202	640.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
GZD3_k127_869000_1	1009370.ALO_21194	4.108e-55	198.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4H4Y5@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
GZD3_k127_869000_2	345341.KUTG_04140	1.074e-11	70.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_869000_0	1382306.JNIM01000001_gene1290	4.136e-134	432.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
GZD3_k127_878264_25	388399.SSE37_17608	3.175e-19	94.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,2U9QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
GZD3_k127_878264_3	546273.VEIDISOL_01555	1.795e-144	481.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
GZD3_k127_878264_10	1968.JOEV01000007_gene4120	2.216e-86	289.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_878264_0	1382306.JNIM01000001_gene512	9.198e-170	559.0	COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA_2
GZD3_k127_878264_20	485913.Krac_8735	5.041e-40	165.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
GZD3_k127_878264_2	1382306.JNIM01000001_gene1548	8.588e-158	531.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_878264_5	485913.Krac_11254	2.982e-114	383.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
GZD3_k127_878264_24	479434.Sthe_1694	2.179e-22	102.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,27YBI@189775|Thermomicrobia	189775|Thermomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
GZD3_k127_878264_18	485913.Krac_11252	2.342e-41	163.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
GZD3_k127_878264_11	485913.Krac_11251	1.131e-71	255.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
GZD3_k127_878264_15	1382306.JNIM01000001_gene607	4.672e-57	216.0	COG1732@1|root,COG1732@2|Bacteria,2G6YB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
GZD3_k127_878264_14	1382306.JNIM01000001_gene608	9.065e-59	211.0	COG1174@1|root,COG1174@2|Bacteria,2G7DK@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
GZD3_k127_878264_16	1382306.JNIM01000001_gene609	9.453e-56	203.0	COG1174@1|root,COG1174@2|Bacteria,2G8XF@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
GZD3_k127_878264_7	1382306.JNIM01000001_gene610	1.759e-110	368.0	COG1125@1|root,COG1125@2|Bacteria,2G7N7@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
GZD3_k127_878264_22	479434.Sthe_1819	7.241e-35	143.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
GZD3_k127_878264_4	196367.JNFG01000020_gene4719	5.788e-120	395.0	COG2042@1|root,COG3376@2|Bacteria,1MUYH@1224|Proteobacteria,2VP4K@28216|Betaproteobacteria,1KHKF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	hoxN	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
GZD3_k127_878264_26	696281.Desru_0683	3.031e-06	58.0	COG5083@1|root,COG5083@2|Bacteria,1VKYI@1239|Firmicutes,24VEI@186801|Clostridia	186801|Clostridia	S	phosphatidylinositol transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
GZD3_k127_878264_9	485913.Krac_8704	4.922e-93	316.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_878264_12	1382306.JNIM01000001_gene3849	1.534e-66	242.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
GZD3_k127_878264_13	1382306.JNIM01000001_gene3896	8.966e-63	223.0	COG2945@1|root,COG2945@2|Bacteria,2G9MQ@200795|Chloroflexi	200795|Chloroflexi	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
GZD3_k127_878264_21	1382306.JNIM01000001_gene1642	3.67e-35	138.0	COG1051@1|root,COG1051@2|Bacteria,2G8SP@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_878264_1	330214.NIDE2961	2.436e-165	527.0	COG3177@1|root,COG3177@2|Bacteria,3J0W5@40117|Nitrospirae	40117|Nitrospirae	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
GZD3_k127_878264_6	1382306.JNIM01000001_gene4102	3.026e-112	382.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
GZD3_k127_878264_8	1382306.JNIM01000001_gene3582	2.146e-94	319.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi	200795|Chloroflexi	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
GZD3_k127_878264_23	671143.DAMO_0701	2.055e-30	134.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
GZD3_k127_878264_19	861299.J421_4181	3.409e-41	166.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
GZD3_k127_891905_1	1382306.JNIM01000001_gene990	3.892e-68	257.0	COG0643@1|root,COG0643@2|Bacteria,2G6G3@200795|Chloroflexi	200795|Chloroflexi	T	ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
GZD3_k127_891905_0	1382306.JNIM01000001_gene989	1.094e-159	524.0	COG0840@1|root,COG0840@2|Bacteria,2G716@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
GZD3_k127_891905_2	1382306.JNIM01000001_gene988	1.041e-35	145.0	COG0835@1|root,COG0835@2|Bacteria,2G9DZ@200795|Chloroflexi	200795|Chloroflexi	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
GZD3_k127_891905_3	485913.Krac_7564	1.76e-19	88.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_7564|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_902732_2	886293.Sinac_4315	4.253e-47	177.0	COG0500@1|root,COG2226@2|Bacteria,2J382@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
GZD3_k127_902732_3	479434.Sthe_2355	9.389e-26	110.0	2DXXV@1|root,3474P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_902732_1	479434.Sthe_2354	6.282e-62	222.0	2F19C@1|root,33UAD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_902732_4	504472.Slin_1443	8.567e-21	94.0	2E46S@1|root,32Z2Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_902732_0	1382306.JNIM01000001_gene4107	8.446e-119	392.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
GZD3_k127_905208_4	1120971.AUCA01000009_gene1987	1.292e-35	143.0	COG0454@1|root,COG0456@2|Bacteria,1VJPU@1239|Firmicutes,4HXYC@91061|Bacilli,27AFB@186823|Alicyclobacillaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
GZD3_k127_905208_0	485913.Krac_7530	1.029e-88	312.0	COG0477@1|root,COG2211@1|root,COG2211@2|Bacteria,COG2814@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_905208_1	1382306.JNIM01000001_gene3651	7.362e-52	196.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
GZD3_k127_905208_2	1382306.JNIM01000001_gene3184	4.523e-48	176.0	COG0432@1|root,COG0432@2|Bacteria,2G9B9@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
GZD3_k127_905208_3	485913.Krac_5403	4.437e-43	164.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269,HIT
GZD3_k127_905208_6	706587.Desti_5608	1.376e-10	68.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
GZD3_k127_905208_5	1382306.JNIM01000001_gene4214	5.849e-20	93.0	COG1565@1|root,COG1565@2|Bacteria,2G8NS@200795|Chloroflexi	200795|Chloroflexi	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
GZD3_k127_908374_2	485913.Krac_8049	9.91e-46	180.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GZD3_k127_908374_1	485913.Krac_8048	2.084e-116	394.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
GZD3_k127_908374_0	1382306.JNIM01000001_gene3281	2.371e-175	561.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
GZD3_k127_908374_3	1382306.JNIM01000001_gene3282	1.645e-22	98.0	COG0277@1|root,COG0277@2|Bacteria,2G7TD@200795|Chloroflexi	200795|Chloroflexi	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
GZD3_k127_909190_1	1128421.JAGA01000001_gene2176	1.024e-33	134.0	COG2141@1|root,COG2141@2|Bacteria,2NQMQ@2323|unclassified Bacteria	2|Bacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
GZD3_k127_909190_0	485913.Krac_12372	1.214e-120	401.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
GZD3_k127_909233_2	926569.ANT_28800	2.528e-94	316.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
GZD3_k127_909233_0	926569.ANT_28810	2.15e-175	557.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
GZD3_k127_909233_1	926569.ANT_28820	7.362e-155	494.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
GZD3_k127_910208_3	443598.AUFA01000004_gene5213	1.48e-19	91.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria,3JSWR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD3_k127_910208_1	234267.Acid_6457	1.585e-66	243.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
GZD3_k127_910208_2	1125863.JAFN01000001_gene825	1.024e-32	141.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1R9H3@1224|Proteobacteria,42XHN@68525|delta/epsilon subdivisions,2WT8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_910208_5	882082.SaccyDRAFT_4146	2.59e-05	53.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E0FJ@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
GZD3_k127_910208_0	485913.Krac_2570	5.406e-210	666.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
GZD3_k127_9146_4	1382306.JNIM01000001_gene4154	2.638e-19	94.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD3_k127_9146_2	1278073.MYSTI_04762	7.454e-82	283.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
GZD3_k127_9146_0	671143.DAMO_2938	1.692e-269	843.0	COG1274@1|root,COG1274@2|Bacteria,2NQRD@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	pckG	-	4.1.1.32,4.1.1.49	ko:K01596,ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003,M00170	R00341,R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP,PEPCK_C,PEPCK_N
GZD3_k127_9146_5	477974.Daud_2128	7.198e-19	93.0	COG2402@1|root,COG2402@2|Bacteria,1V8M3@1239|Firmicutes,24MAG@186801|Clostridia,2654W@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
GZD3_k127_9146_1	269799.Gmet_3488	5.289e-119	393.0	2DBVK@1|root,2ZBBH@2|Bacteria,1PWZS@1224|Proteobacteria,432W2@68525|delta/epsilon subdivisions,2WXWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
GZD3_k127_9146_3	1382306.JNIM01000001_gene2557	4.269e-39	151.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
GZD3_k127_915703_5	543632.JOJL01000007_gene5175	4.869e-06	49.0	COG1670@1|root,COG3467@1|root,COG1670@2|Bacteria,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4DASD@85008|Micromonosporales	201174|Actinobacteria	J	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Acetyltransf_3,Pyridox_ox_2
GZD3_k127_915703_1	1382306.JNIM01000001_gene3861	5.766e-104	366.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
GZD3_k127_915703_0	1382306.JNIM01000001_gene2518	1.224e-139	476.0	COG0205@1|root,COG0205@2|Bacteria,2G81H@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
GZD3_k127_915703_2	292.DM42_4740	3.02e-43	176.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS6@28216|Betaproteobacteria,1KI5E@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
GZD3_k127_92119_1	1172188.KB911825_gene3602	3.354e-06	55.0	COG3427@1|root,COG3427@2|Bacteria,2IEYK@201174|Actinobacteria,4FG7C@85021|Intrasporangiaceae	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
GZD3_k127_92119_0	1337936.IJ00_09550	3.536e-64	230.0	COG1028@1|root,COG1028@2|Bacteria,1G4S8@1117|Cyanobacteria,1HNVP@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K19550	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11067,R11671	RC00029,RC00117,RC03342	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
GZD3_k127_921668_5	1237500.ANBA01000011_gene3594	0.0002117	51.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4EK02@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_921668_3	246200.SPO0937	3.938e-09	64.0	COG1872@1|root,COG1872@2|Bacteria,1PPC2@1224|Proteobacteria,2V1UJ@28211|Alphaproteobacteria,4NCR3@97050|Ruegeria	28211|Alphaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
GZD3_k127_921668_4	477974.Daud_1411	5.871e-06	52.0	COG0762@1|root,COG0762@2|Bacteria,1URMB@1239|Firmicutes,24RBP@186801|Clostridia,2633K@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
GZD3_k127_921668_1	1382306.JNIM01000001_gene3787	1.602e-51	189.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_921668_0	314278.NB231_04380	7.467e-53	198.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1WWUW@135613|Chromatiales	135613|Chromatiales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
GZD3_k127_921668_2	1122919.KB905550_gene1905	1.244e-10	62.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,26QMM@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the multicopper oxidase YfiH RL5 family	ylmD	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
GZD3_k127_925663_0	485913.Krac_3213	1.71e-178	575.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
GZD3_k127_925663_1	1121946.AUAX01000019_gene7836	1.118e-33	135.0	COG0494@1|root,COG0494@2|Bacteria,2GS19@201174|Actinobacteria,4DFIG@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_92797_0	1382356.JQMP01000003_gene2304	1.077e-78	274.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,27XQR@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
GZD3_k127_92797_1	1382356.JQMP01000003_gene2305	5.575e-50	184.0	arCOG04740@1|root,31PZA@2|Bacteria,2GA0B@200795|Chloroflexi,27Y9E@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_928863_0	485913.Krac_10925	5.48e-96	316.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
GZD3_k127_928863_1	485913.Krac_4146	5.374e-31	127.0	2EMTZ@1|root,33FGB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
GZD3_k127_934950_0	485913.Krac_11272	1.855e-160	527.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
GZD3_k127_934950_6	1382306.JNIM01000001_gene772	1.195e-43	173.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
GZD3_k127_934950_9	485913.Krac_10275	2.188e-09	69.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	485913.Krac_10275|-	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_934950_5	543728.Vapar_0038	1.474e-62	220.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2W2AU@28216|Betaproteobacteria,4AHNI@80864|Comamonadaceae	28216|Betaproteobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
GZD3_k127_934950_3	324602.Caur_2455	7.589e-72	255.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
GZD3_k127_934950_4	485913.Krac_8544	1.012e-63	230.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
GZD3_k127_934950_2	1123073.KB899243_gene844	3.057e-79	285.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
GZD3_k127_934950_7	1123371.ATXH01000008_gene281	3.238e-39	156.0	COG0587@1|root,COG0587@2|Bacteria,2GGUN@200940|Thermodesulfobacteria	2|Bacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
GZD3_k127_934950_8	1229780.BN381_130136	2.389e-20	92.0	2EF5E@1|root,338YK@2|Bacteria,2GVSB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_934950_1	469383.Cwoe_2559	3.249e-101	341.0	COG3191@1|root,COG3191@2|Bacteria,2H89D@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
GZD3_k127_93975_4	485913.Krac_2662	1.017e-83	282.0	COG1028@1|root,COG1028@2|Bacteria,2G5R0@200795|Chloroflexi	200795|Chloroflexi	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
GZD3_k127_93975_1	1128421.JAGA01000002_gene1496	7.399e-202	635.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
GZD3_k127_93975_6	710696.Intca_1692	2.72e-18	100.0	COG0166@1|root,COG0166@2|Bacteria,2HX58@201174|Actinobacteria,4FEPU@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glucose-6-phosphate isomerase	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
GZD3_k127_93975_3	1382306.JNIM01000001_gene1936	1.047e-92	317.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
GZD3_k127_93975_0	1382306.JNIM01000001_gene1937	2.117e-203	640.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
GZD3_k127_93975_2	485913.Krac_8133	2.535e-148	484.0	COG4608@1|root,COG4608@2|Bacteria,2G80T@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
GZD3_k127_93975_5	1382306.JNIM01000001_gene1676	2.684e-53	192.0	COG0444@1|root,COG0444@2|Bacteria,2G6CC@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
GZD3_k127_952225_1	240015.ACP_3304	4.515e-23	103.0	COG3548@1|root,COG3548@2|Bacteria,3Y607@57723|Acidobacteria,2JMVT@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
GZD3_k127_952225_0	485913.Krac_7992	1.611e-174	565.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	200795|Chloroflexi	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
GZD3_k127_952456_4	1382306.JNIM01000001_gene1054	1.316e-71	250.0	COG1641@1|root,COG1641@2|Bacteria,2G5MP@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
GZD3_k127_952456_8	1380390.JIAT01000011_gene2542	4.091e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
GZD3_k127_952456_1	1172188.KB911834_gene4138	2.486e-146	499.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
GZD3_k127_952456_7	485913.Krac_6656	1.994e-22	112.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF1992)	-	-	-	ko:K19373	-	-	-	-	ko00000,ko03110	-	-	-	DUF1992
GZD3_k127_952456_0	485913.Krac_10609	2.089e-206	653.0	COG1488@1|root,COG1488@2|Bacteria,2G70D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	-
GZD3_k127_952456_6	888816.HMPREF9389_1487	1.427e-25	112.0	COG1510@1|root,COG1510@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,MarR,MarR_2
GZD3_k127_952456_2	1382306.JNIM01000001_gene464	7.581e-132	426.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
GZD3_k127_952456_3	1382306.JNIM01000001_gene463	1.734e-103	357.0	COG3559@1|root,COG3559@2|Bacteria,2G7I8@200795|Chloroflexi	200795|Chloroflexi	M	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
GZD3_k127_952456_5	485913.Krac_8460	4.583e-49	186.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
GZD3_k127_96354_0	1382306.JNIM01000001_gene861	3.595e-157	503.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
GZD3_k127_96354_3	1111729.ATYV01000002_gene2104	2.461e-12	80.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,22JKG@1653|Corynebacteriaceae	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
GZD3_k127_96354_1	1382306.JNIM01000001_gene3428	1.888e-76	269.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,Pkinase,TIR_2,WD40
GZD3_k127_96354_2	485913.Krac_1354	2.19e-21	98.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
GZD3_k127_968330_0	485913.Krac_1212	9.626e-93	310.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi	200795|Chloroflexi	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_968330_2	479434.Sthe_1864	5.042e-59	214.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi,27YFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
GZD3_k127_968330_1	1499967.BAYZ01000131_gene338	3.834e-63	225.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	uma2	-	-	-	-	-	-	-	-	-	-	-	Uma2
GZD3_k127_968330_3	485913.Krac_7679	5.002e-29	122.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH,HMG-CoA_red
GZD3_k127_974919_1	1382306.JNIM01000001_gene617	1.154e-63	228.0	COG1686@1|root,COG1686@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase2,PG_binding_1,Peptidase_S11
GZD3_k127_974919_0	1382306.JNIM01000001_gene3948	4.185e-91	314.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	200795|Chloroflexi	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
GZD3_k127_974919_2	926569.ANT_22580	2.188e-51	204.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
GZD3_k127_984891_1	709986.Deima_0601	2.869e-43	172.0	COG0388@1|root,COG0388@2|Bacteria,1WJ47@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
GZD3_k127_984891_3	1382306.JNIM01000001_gene539	2.423e-14	84.0	2EIKM@1|root,33CBX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_984891_0	485913.Krac_4797	6.293e-85	300.0	2DMGS@1|root,32RE8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_984891_2	1123239.KB898624_gene1739	9.203e-29	124.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli	91061|Bacilli	L	AdP-ribose pyrophosphatase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
GZD3_k127_984891_4	220341.16502318	1.145e-06	51.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,3ZKG9@590|Salmonella	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
GZD3_k127_998771_2	1121127.JAFA01000027_gene154	3.961e-29	118.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,1K44Y@119060|Burkholderiaceae	28216|Betaproteobacteria	I	synthetase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
GZD3_k127_998771_1	1111728.ATYS01000016_gene4671	1.62e-44	171.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RN8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the BI1 family	ybhL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
GZD3_k127_998771_5	485913.Krac_4609	9.87e-08	60.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
GZD3_k127_998771_0	1382306.JNIM01000001_gene3941	1.561e-118	398.0	COG0726@1|root,COG2211@1|root,COG0726@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Polysacc_deac_1
GZD3_k127_998771_3	575615.HMPREF0670_02906	1.009e-17	91.0	2DNPH@1|root,32YF1@2|Bacteria,4NVUP@976|Bacteroidetes,2FZDB@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GZD3_k127_998771_4	211165.AJLN01000021_gene2775	2.082e-15	83.0	2A7FA@1|root,30WCV@2|Bacteria,1GFDD@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 3722 queries scanned
## Total time (seconds): 248.84431290626526
## Rate: 14.96 q/s