## Fri Nov 15 12:26:44 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin8/HKD_1_bin.56.fa -m mmseqs --itype genome -o HKD_1_bin.56 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_1_bin.56 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD1_k127_1005307_1	761193.Runsl_5621	2.559e-94	314.0	COG0151@1|root,COG0151@2|Bacteria,4P144@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1005307_0	1123037.AUDE01000005_gene3088	3.902e-163	555.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
HKD1_k127_1010115_0	700598.Niako_5138	0.0	1080.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
HKD1_k127_1010115_1	1453505.JASY01000024_gene295	1.47e-145	482.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXNE@117743|Flavobacteriia,2NT5A@237|Flavobacterium	976|Bacteroidetes	P	Tonb-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_1010413_0	925409.KI911562_gene724	0.0	1058.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1IV6E@117747|Sphingobacteriia	976|Bacteroidetes	CI	MaoC like domain	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
HKD1_k127_1010413_3	929713.NIASO_14595	4.11e-76	261.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
HKD1_k127_1010413_2	700598.Niako_6072	7.981e-90	299.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISB0@117747|Sphingobacteriia	976|Bacteroidetes	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD1_k127_1010413_1	925409.KI911562_gene1358	6.469e-158	508.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1IP4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_102680_1	1492737.FEM08_01170	8.823e-15	74.0	COG2985@1|root,COG2985@2|Bacteria,4NHM3@976|Bacteroidetes,1IIQ6@117743|Flavobacteriia,2NUWV@237|Flavobacterium	976|Bacteroidetes	U	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
HKD1_k127_102680_0	1239962.C943_00093	7.079e-169	544.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,47KT5@768503|Cytophagia	976|Bacteroidetes	U	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
HKD1_k127_1039235_3	1131812.JQMS01000001_gene941	3.733e-57	206.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia,2NYX7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1039235_1	700598.Niako_4877	7.579e-155	492.0	COG2207@1|root,COG2207@2|Bacteria,4NEHD@976|Bacteroidetes,1IPPP@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_1039235_0	1089547.KB913013_gene4772	9.415e-252	784.0	COG1231@1|root,COG1231@2|Bacteria,4PMAQ@976|Bacteroidetes,47N7X@768503|Cytophagia	976|Bacteroidetes	E	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
HKD1_k127_1039235_2	1123276.KB893269_gene4787	2.246e-69	237.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47JBA@768503|Cytophagia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD1_k127_1044873_0	929713.NIASO_06985	8.406e-78	268.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HKD1_k127_1044873_1	1237149.C900_05681	4.641e-49	181.0	COG2367@1|root,COG2866@1|root,COG2367@2|Bacteria,COG2866@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
HKD1_k127_1048333_8	755732.Fluta_3745	4.414e-24	116.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,2PBN9@246874|Cryomorphaceae	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_1048333_1	700598.Niako_7085	2.751e-208	655.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1IPFD@117747|Sphingobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD1_k127_1048333_5	925409.KI911562_gene1315	2.024e-85	290.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD1_k127_1048333_6	700598.Niako_7080	5.927e-66	231.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD1_k127_1048333_7	700598.Niako_7079	2.411e-57	207.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1IRXT@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD1_k127_1048333_4	929713.NIASO_11585	4.276e-125	407.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD1_k127_1048333_2	700598.Niako_7076	3.966e-149	483.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_1048333_0	485918.Cpin_1424	0.0	1018.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
HKD1_k127_1048333_3	700598.Niako_7075	1.11e-140	453.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD1_k127_1049563_6	706587.Desti_4215	8.929e-21	101.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD1_k127_1049563_4	522306.CAP2UW1_2085	2.568e-83	287.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1KQA5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transporter	-	-	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	-	PHO4
HKD1_k127_1049563_2	925409.KI911562_gene510	2.243e-125	406.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1IQAN@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HKD1_k127_1049563_1	1122605.KB893628_gene4413	8.602e-128	417.0	COG1819@1|root,COG1819@2|Bacteria,4NFYF@976|Bacteroidetes,1IPCN@117747|Sphingobacteriia	976|Bacteroidetes	CG	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
HKD1_k127_1049563_0	1123248.KB893340_gene2674	3.629e-136	436.0	COG0639@1|root,COG0639@2|Bacteria,4NFPU@976|Bacteroidetes,1IRZS@117747|Sphingobacteriia	976|Bacteroidetes	T	Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD1_k127_1049563_3	1356852.N008_16220	2.772e-92	307.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,47XMI@768503|Cytophagia	976|Bacteroidetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
HKD1_k127_1049563_5	929713.NIASO_09835	1.522e-34	133.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
HKD1_k127_1053956_1	509635.N824_06010	1.308e-193	613.0	COG0833@1|root,COG0833@2|Bacteria,4PN7J@976|Bacteroidetes,1IQ7E@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
HKD1_k127_1053956_0	509635.N824_06005	8.317e-229	715.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD1_k127_1053956_2	509635.N824_06000	9.828e-64	221.0	COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,1ISP5@117747|Sphingobacteriia	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HKD1_k127_1060424_0	925409.KI911562_gene1602	3.217e-199	625.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1INWU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD1_k127_1060424_1	700598.Niako_1182	1.478e-93	310.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,1IXWW@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD1_k127_1060424_2	700598.Niako_1183	1.972e-46	172.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1IZMA@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM AhpC TSA family	trxC	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
HKD1_k127_1065093_5	984262.SGRA_1168	6.185e-32	132.0	COG4485@1|root,COG4485@2|Bacteria,4NUQF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD1_k127_1065093_2	929556.Solca_3493	1.204e-79	277.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD1_k127_1065093_1	1047013.AQSP01000081_gene101	5.059e-108	355.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_1065093_4	1492737.FEM08_07260	2.223e-38	148.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,1I3DZ@117743|Flavobacteriia,2NWHH@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD1_k127_1065093_3	700598.Niako_1569	9.493e-47	170.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,1ITGF@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
HKD1_k127_1065093_0	1122605.KB893645_gene1113	0.0	1428.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD1_k127_1080205_3	1121481.AUAS01000008_gene3001	2.564e-242	774.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD1_k127_1080205_9	700598.Niako_5756	2.41e-23	100.0	2BZQY@1|root,2ZVH4@2|Bacteria,4P73I@976|Bacteroidetes,1IZGJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1080205_0	700598.Niako_5757	0.0	1137.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD1_k127_1080205_2	925409.KI911562_gene1263	4.111e-254	790.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
HKD1_k127_1080205_6	1122605.KB893644_gene1476	3.729e-170	540.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1IP38@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD1_k127_1080205_5	700598.Niako_6962	6.37e-183	580.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
HKD1_k127_1080205_1	700598.Niako_6963	5.411e-297	916.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
HKD1_k127_1080205_8	929713.NIASO_18595	2.574e-32	128.0	2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,1ITUK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1080205_7	700598.Niako_6965	1.345e-117	382.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1INS0@117747|Sphingobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
HKD1_k127_1080205_4	700598.Niako_6969	3.43e-206	646.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_1089646_6	925409.KI911562_gene2794	6.615e-17	83.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1IQ2Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD1_k127_1089646_0	700598.Niako_4507	6.385e-202	632.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
HKD1_k127_1089646_3	1123248.KB893317_gene4325	8.091e-117	381.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1IPH1@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HKD1_k127_1089646_1	925409.KI911562_gene2798	1.02e-182	578.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1IW5P@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_1089646_2	700598.Niako_4511	2.22e-135	436.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1IQJU@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
HKD1_k127_1089646_5	1267211.KI669560_gene2266	4.113e-76	259.0	COG1595@1|root,COG1595@2|Bacteria,4NM40@976|Bacteroidetes,1IRKZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HKD1_k127_1089646_4	1122605.KB893625_gene1822	3.73e-115	379.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,1IPPQ@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
HKD1_k127_1092399_1	504472.Slin_1717	9.222e-236	737.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
HKD1_k127_1092399_0	760192.Halhy_3928	1.01e-253	789.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1IVMQ@117747|Sphingobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
HKD1_k127_1092399_2	762903.Pedsa_2202	2.786e-08	55.0	COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,1IRR9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Oxidoreduct_C
HKD1_k127_1094790_6	1267211.KI669560_gene96	1.974e-56	199.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_1094790_4	700598.Niako_6495	4.897e-67	233.0	COG1846@1|root,COG1846@2|Bacteria,4NSNN@976|Bacteroidetes,1ITUW@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_1094790_0	700598.Niako_6492	1.452e-120	397.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD1_k127_1094790_3	700598.Niako_6489	3.054e-72	246.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1IRYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD1_k127_1094790_2	1122605.KB893628_gene4450	1.065e-98	327.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HKD1_k127_1094790_7	700598.Niako_6484	8.155e-51	183.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1IT8P@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
HKD1_k127_1094790_5	761193.Runsl_2774	5.161e-67	241.0	COG2267@1|root,COG2267@2|Bacteria,4NKKQ@976|Bacteroidetes,47STZ@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD1_k127_1094790_1	1396141.BATP01000040_gene2167	1.469e-104	352.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD1_k127_1094790_8	926559.JoomaDRAFT_3030	9.859e-32	135.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD1_k127_1096271_0	700598.Niako_6743	2.555e-130	421.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IQFR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD1_k127_1096271_1	700598.Niako_6744	6.854e-61	214.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,1IY1X@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Transcription antitermination protein, NusG, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	KOW,NusG
HKD1_k127_1096271_3	1122605.KB893647_gene400	4.338e-47	179.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes	976|Bacteroidetes	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
HKD1_k127_1096271_2	1122605.KB893647_gene401	6.325e-50	190.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD1_k127_1098578_0	1123248.KB893348_gene140	0.0	1277.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,1IRMN@117747|Sphingobacteriia	976|Bacteroidetes	CG	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
HKD1_k127_1098578_1	700598.Niako_7310	1.072e-87	292.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
HKD1_k127_1098578_2	700598.Niako_7311	4.157e-81	280.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1J0U6@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD1_k127_1105032_0	649349.Lbys_3305	7.449e-138	448.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,47KJN@768503|Cytophagia	976|Bacteroidetes	EG	TIGRFAM gluconate transporter	-	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
HKD1_k127_1105032_1	700598.Niako_6788	5.638e-58	205.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
HKD1_k127_1105032_2	700598.Niako_6788	4.463e-07	52.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
HKD1_k127_112230_1	1121904.ARBP01000012_gene1338	2.526e-165	528.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,47MSW@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
HKD1_k127_112230_2	1121904.ARBP01000012_gene1339	4.648e-165	526.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes,47NV0@768503|Cytophagia	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
HKD1_k127_112230_6	143224.JQMD01000002_gene4158	2.099e-84	283.0	COG0526@1|root,COG0526@2|Bacteria,4PKKF@976|Bacteroidetes,1IJBT@117743|Flavobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
HKD1_k127_112230_9	1123248.KB893381_gene1007	4.133e-19	91.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
HKD1_k127_112230_0	1267211.KI669560_gene405	5.399e-193	610.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes	976|Bacteroidetes	E	peptidase, M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD1_k127_112230_5	1123248.KB893348_gene253	4.481e-86	293.0	COG0115@1|root,COG0115@2|Bacteria,4PFUA@976|Bacteroidetes,1IS3V@117747|Sphingobacteriia	976|Bacteroidetes	EH	Amino-transferase class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD1_k127_112230_3	1123234.AUKI01000024_gene2105	1.664e-158	507.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1HZRM@117743|Flavobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
HKD1_k127_112230_4	1123248.KB893314_gene3562	3.342e-157	508.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,1IPJY@117747|Sphingobacteriia	976|Bacteroidetes	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
HKD1_k127_112230_8	1123248.KB893314_gene3563	9.574e-35	134.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1IRDU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD1_k127_1124169_0	1122605.KB893628_gene4542	7.634e-278	858.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD1_k127_1124169_1	700598.Niako_6419	3.23e-85	291.0	COG0589@1|root,COG0589@2|Bacteria,4PICK@976|Bacteroidetes,1IXMG@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_1124169_2	700598.Niako_6420	3.735e-38	149.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
HKD1_k127_1129394_1	1123248.KB893319_gene3959	1.103e-149	484.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1IPBV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
HKD1_k127_1129394_0	1122605.KB893626_gene2516	1.721e-268	844.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HKD1_k127_1136503_1	700598.Niako_3442	5.911e-123	395.0	COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1136503_0	700598.Niako_0913	3.172e-171	548.0	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,1IXI6@117747|Sphingobacteriia	976|Bacteroidetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_1136503_3	1506583.JQJY01000008_gene3801	1.048e-11	75.0	29SSC@1|root,30DYA@2|Bacteria,4NNZT@976|Bacteroidetes,1IJ20@117743|Flavobacteriia,2NU5Q@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
HKD1_k127_1136503_2	700598.Niako_0915	9.065e-25	104.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1ISB1@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA methyltransferase, RsmD	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD1_k127_113688_5	694427.Palpr_1339	4.909e-15	83.0	COG0526@1|root,COG0526@2|Bacteria	694427.Palpr_1339|-	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_113688_0	1121930.AQXG01000003_gene2706	8.152e-85	284.0	COG4430@1|root,COG4430@2|Bacteria,4NG4C@976|Bacteroidetes,1IRYH@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
HKD1_k127_113688_3	1123277.KB893239_gene1287	8.221e-50	181.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,47QHF@768503|Cytophagia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
HKD1_k127_113688_1	1123248.KB893320_gene3950	1.032e-72	248.0	COG3832@1|root,COG3832@2|Bacteria,4NM7P@976|Bacteroidetes,1ISPW@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_113688_2	485918.Cpin_4829	2.018e-50	180.0	COG0640@1|root,COG0640@2|Bacteria,4NQ33@976|Bacteroidetes,1IT71@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD1_k127_1141608_2	1121957.ATVL01000008_gene4308	2.041e-95	315.0	COG0500@1|root,COG2226@2|Bacteria,4NJTP@976|Bacteroidetes,47UFD@768503|Cytophagia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
HKD1_k127_1141608_1	1150600.ADIARSV_3675	4.191e-100	331.0	COG2020@1|root,COG2020@2|Bacteria,4NJCI@976|Bacteroidetes,1IUCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
HKD1_k127_1141608_0	700598.Niako_6283	6.044e-117	383.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1IXIZ@117747|Sphingobacteriia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
HKD1_k127_1141608_3	1123248.KB893370_gene5024	6.149e-48	176.0	COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,1IS9Q@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HKD1_k127_114801_2	700598.Niako_6066	8.52e-74	254.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1IRZT@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
HKD1_k127_114801_1	700598.Niako_6065	1.385e-82	278.0	COG0122@1|root,COG0122@2|Bacteria,4NMMI@976|Bacteroidetes,1IU7D@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
HKD1_k127_114801_0	1123023.JIAI01000003_gene3109	4.544e-85	293.0	COG0500@1|root,COG2226@2|Bacteria,2IFUV@201174|Actinobacteria	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
HKD1_k127_114801_3	1122605.KB893628_gene4485	3.424e-24	103.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD1_k127_1148226_1	700598.Niako_2288	6.903e-71	246.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
HKD1_k127_1148226_0	1121904.ARBP01000002_gene7252	1.424e-242	774.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_1148226_2	700598.Niako_0195	7.363e-18	87.0	2DREE@1|root,33BDM@2|Bacteria,4NXHP@976|Bacteroidetes	976|Bacteroidetes	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
HKD1_k127_1150525_10	1122605.KB893647_gene276	8.131e-16	77.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_1150525_8	929713.NIASO_13715	3.319e-25	109.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD1_k127_1150525_4	929713.NIASO_13710	9.216e-60	209.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD1_k127_1150525_3	1122605.KB893627_gene2959	8.556e-88	295.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HKD1_k127_1150525_5	1123248.KB893348_gene106	7.239e-58	203.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1ISQF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1150525_7	717774.Marme_0544	9.569e-56	198.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,1T1S0@1236|Gammaproteobacteria,1XKQ3@135619|Oceanospirillales	135619|Oceanospirillales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD1_k127_1150525_0	700598.Niako_5752	1.965e-214	672.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD1_k127_1150525_2	991.IW20_07695	8.561e-108	358.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia,2P0JV@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD1_k127_1150525_6	700598.Niako_0339	9.321e-58	214.0	COG4783@1|root,COG4783@2|Bacteria,4NP8B@976|Bacteroidetes,1IXV9@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD1_k127_1150525_9	700598.Niako_5753	1.544e-19	96.0	2EK5X@1|root,33DWB@2|Bacteria	2|Bacteria	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_1150525_1	700598.Niako_5754	1.444e-129	421.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IR4K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
HKD1_k127_1159370_0	485918.Cpin_4291	2.179e-181	599.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_1178116_1	929713.NIASO_04805	1.108e-44	165.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HKD1_k127_1178116_2	700598.Niako_6683	7.83e-24	111.0	2BRQH@1|root,32KQ7@2|Bacteria,4NZEF@976|Bacteroidetes,1IUQU@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1178116_0	700598.Niako_0902	5.29e-148	474.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD1_k127_1178116_3	700598.Niako_0900	7.463e-05	45.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1182117_0	700598.Niako_6203	1.035e-112	368.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1IV58@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD1_k127_1182117_1	1267211.KI669560_gene737	2.076e-56	200.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes	976|Bacteroidetes	Q	phenylacetic acid degradation protein	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
HKD1_k127_118750_0	929556.Solca_0522	7.226e-115	373.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_118750_1	1122176.KB903537_gene1656	2.705e-57	213.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
HKD1_k127_1192724_1	700598.Niako_0374	1.241e-40	154.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1IU3X@117747|Sphingobacteriia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
HKD1_k127_1192724_2	700598.Niako_0373	6.091e-38	146.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1IT7G@117747|Sphingobacteriia	976|Bacteroidetes	M	peptidase M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_1192724_0	700598.Niako_0372	3.91e-258	829.0	COG0457@1|root,COG1729@1|root,COG3147@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3147@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
HKD1_k127_1192724_3	925409.KI911562_gene1990	1.411e-08	56.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD1_k127_1193141_3	1123057.P872_07695	8.409e-21	93.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1193141_1	313596.RB2501_04010	1.985e-131	438.0	COG2114@1|root,COG2114@2|Bacteria,4PMA6@976|Bacteroidetes,1IJPA@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,Guanylate_cyc
HKD1_k127_1193141_2	118173.KB235914_gene2451	5.694e-55	194.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD1_k127_1193141_0	1267534.KB906756_gene667	1.433e-255	836.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PilZ,Response_reg,Y_Y_Y
HKD1_k127_1196153_0	1122605.KB893645_gene1004	5.35e-113	366.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD1_k127_1196153_1	1122605.KB893645_gene1003	2.361e-58	211.0	298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1196153_2	700598.Niako_5045	7.732e-57	207.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1IVJP@117747|Sphingobacteriia	976|Bacteroidetes	O	S53, subtilisin kexin sedolisin	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_1197065_5	661478.OP10G_2564	3.558e-94	310.0	COG1028@1|root,COG1028@2|Bacteria	661478.OP10G_2564|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1197065_7	714943.Mucpa_4555	1.315e-42	160.0	2EB0S@1|root,3351M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1197065_2	926549.KI421517_gene1057	3.154e-134	433.0	COG4989@1|root,COG4989@2|Bacteria,4NENV@976|Bacteroidetes,47NAR@768503|Cytophagia	976|Bacteroidetes	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD1_k127_1197065_6	929713.NIASO_14860	3.456e-93	311.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,1IQTT@117747|Sphingobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HKD1_k127_1197065_3	1122605.KB893628_gene4422	1.052e-124	406.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_1197065_10	700598.Niako_7046	2.178e-08	64.0	COG3678@1|root,COG3678@2|Bacteria,4NYJD@976|Bacteroidetes	976|Bacteroidetes	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1197065_8	760192.Halhy_3780	1.075e-39	164.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
HKD1_k127_1197065_0	700598.Niako_7047	1.141e-184	582.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD1_k127_1197065_9	1288963.ADIS_4839	1.777e-36	140.0	COG2026@1|root,COG2026@2|Bacteria,4NW0W@976|Bacteroidetes,47R8J@768503|Cytophagia	976|Bacteroidetes	DJ	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
HKD1_k127_1197065_1	925409.KI911562_gene221	3.509e-180	571.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IVK0@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	2.3.1.174,2.3.1.9	ko:K00626,ko:K07823	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD1_k127_1197065_4	509635.N824_06780	4.2e-102	349.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IR3U@117747|Sphingobacteriia	976|Bacteroidetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD1_k127_1197910_1	700598.Niako_0166	1.056e-154	493.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
HKD1_k127_1197910_0	1123248.KB893320_gene3871	2.117e-158	506.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
HKD1_k127_1197910_2	700598.Niako_1117	8.495e-114	377.0	COG3291@1|root,COG3291@2|Bacteria,4NV8C@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD1_k127_1213159_0	247634.GPB2148_3282	3.775e-130	437.0	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1J8Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
HKD1_k127_1213159_2	760192.Halhy_6349	1.544e-85	287.0	COG2129@1|root,COG2129@2|Bacteria,4NNRJ@976|Bacteroidetes,1IS60@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HKD1_k127_1213159_3	1121899.Q764_10530	1.063e-13	74.0	2A9ZJ@1|root,30Z80@2|Bacteria,4PDCX@976|Bacteroidetes,1INEI@117743|Flavobacteriia,2NZBA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1213159_1	760192.Halhy_0957	1.17e-107	361.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
HKD1_k127_1213159_4	1094980.Mpsy_0765	4.18e-05	49.0	COG0662@1|root,COG0840@1|root,arCOG03003@2157|Archaea,arCOG03642@2157|Archaea,2Y1J0@28890|Euryarchaeota,2NA4T@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_1223596_0	1229487.AMYW01000009_gene1267	5.479e-113	370.0	2DH0T@1|root,32U8E@2|Bacteria,4NSCU@976|Bacteroidetes,1I8EH@117743|Flavobacteriia,2NYV2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1223596_3	1348583.ATLH01000001_gene3738	8.035e-05	51.0	2BI62@1|root,32CBB@2|Bacteria,4NQGF@976|Bacteroidetes,1I3F8@117743|Flavobacteriia,1FAG2@104264|Cellulophaga	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
HKD1_k127_1223596_1	313596.RB2501_04465	9.649e-10	68.0	COG3631@1|root,COG3631@2|Bacteria,4P352@976|Bacteroidetes,1I9A0@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD1_k127_1223596_2	926560.KE387023_gene3356	2.066e-08	61.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
HKD1_k127_1231451_1	929713.NIASO_07805	1.689e-97	320.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1IS2H@117747|Sphingobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD1_k127_1231451_3	929713.NIASO_07810	3.126e-83	281.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
HKD1_k127_1231451_2	1122605.KB893625_gene2079	5.66e-92	307.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,1INSK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
HKD1_k127_1231451_4	1313301.AUGC01000001_gene1747	1.071e-09	61.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1231451_0	700598.Niako_5035	1.058e-220	689.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD1_k127_1241324_0	1122605.KB893643_gene876	9.429e-135	437.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1IP9N@117747|Sphingobacteriia	976|Bacteroidetes	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
HKD1_k127_1241324_2	929556.Solca_3122	6.006e-30	123.0	2C19F@1|root,32ZRH@2|Bacteria,4NUG5@976|Bacteroidetes,1IYGV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1241324_1	700598.Niako_1154	2.561e-65	235.0	2DNQ3@1|root,32YIN@2|Bacteria,4NUWB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_125192_0	1123248.KB893314_gene3581	6.863e-86	288.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD1_k127_125192_2	1267211.KI669560_gene445	2.495e-35	139.0	2D0AC@1|root,32T87@2|Bacteria,4NSVN@976|Bacteroidetes,1ITAV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_125192_1	153721.MYP_2946	1.085e-59	219.0	COG1994@1|root,COG1994@2|Bacteria,4NRNR@976|Bacteroidetes,47UP8@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_125192_3	700598.Niako_4414	7.935e-23	99.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IYEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD1_k127_126168_0	1047013.AQSP01000017_gene1088	3.566e-84	287.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
HKD1_k127_126168_2	929556.Solca_3835	3.965e-06	49.0	COG0346@1|root,COG0346@2|Bacteria,4NZS3@976|Bacteroidetes	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_126168_1	1197477.IA57_03205	2.392e-06	52.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1I08M@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_1267154_1	1123248.KB893318_gene4154	1.308e-84	291.0	COG5279@1|root,COG5279@2|Bacteria,4NKJ4@976|Bacteroidetes,1IYXJ@117747|Sphingobacteriia	976|Bacteroidetes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HKD1_k127_1267154_2	700598.Niako_1649	8.36e-33	130.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
HKD1_k127_1267154_0	760192.Halhy_1605	0.0	1397.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_1271714_2	1250232.JQNJ01000001_gene3397	8.382e-29	118.0	COG2114@1|root,COG5616@1|root,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_1271714_1	1408813.AYMG01000014_gene1509	2.503e-241	756.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1IQD0@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD1_k127_1271714_0	925409.KI911562_gene1379	4.435e-270	841.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IUT7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_1276048_4	504472.Slin_2140	4.326e-47	173.0	COG1670@1|root,COG1670@2|Bacteria,4NTU9@976|Bacteroidetes,47UWA@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
HKD1_k127_1276048_0	1123248.KB893385_gene4825	8.111e-142	461.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Phage-tail_3,TIG
HKD1_k127_1276048_5	1406840.Q763_14715	3.706e-27	118.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia,2NWGD@237|Flavobacterium	976|Bacteroidetes	K	Pfam Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_1276048_3	1121481.AUAS01000007_gene1160	6.605e-83	309.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NK65@976|Bacteroidetes,47XEZ@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop
HKD1_k127_1276048_1	700598.Niako_4662	5.8e-137	440.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HKD1_k127_1276048_2	700598.Niako_4663	1.893e-98	324.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1IPEC@117747|Sphingobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD1_k127_1281261_3	700598.Niako_0455	1.468e-135	435.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IP6V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140,ko:K22187	ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935,R11768	RC00004,RC00080,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_1281261_6	714943.Mucpa_3725	1.724e-13	81.0	28M39@1|root,2ZAHI@2|Bacteria,4NM3I@976|Bacteroidetes,1IZ0T@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1281261_0	1144313.PMI10_00468	0.0	1368.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia,2NVS6@237|Flavobacterium	976|Bacteroidetes	GM	glycosyl transferase, family 2	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Polysacc_deac_1
HKD1_k127_1281261_4	929713.NIASO_01525	7.706e-128	414.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD1_k127_1281261_1	700598.Niako_4924	1.002e-170	539.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1IP0K@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD1_k127_1281261_5	1123248.KB893337_gene2399	4.722e-65	230.0	COG1376@1|root,COG1376@2|Bacteria,4NNMF@976|Bacteroidetes,1J0D6@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD1_k127_1281261_2	1122605.KB893643_gene677	1.027e-156	499.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_1282470_1	925409.KI911562_gene492	7.071e-161	518.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD1_k127_1282470_3	1267211.KI669560_gene215	3.39e-78	270.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
HKD1_k127_1282470_6	929713.NIASO_17845	6.859e-62	217.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD1_k127_1282470_2	700598.Niako_4356	1.785e-153	499.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD1_k127_1282470_7	929556.Solca_3548	1.022e-35	141.0	COG0457@1|root,COG0457@2|Bacteria,4PPB4@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1282470_0	1267211.KI669560_gene220	1.52e-199	624.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
HKD1_k127_1282470_5	1267211.KI669560_gene229	4.144e-63	222.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1IZCY@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
HKD1_k127_1282470_4	700598.Niako_6574	6.958e-64	225.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD1_k127_1282470_9	700598.Niako_6573	8.682e-22	98.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD1_k127_1284837_0	925409.KI911562_gene1388	0.0	1358.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD1_k127_1284837_7	1202532.FF52_01310	6.363e-66	231.0	2EIHF@1|root,33C8T@2|Bacteria,4NXJY@976|Bacteroidetes,1IMZ5@117743|Flavobacteriia,2NWJY@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1284837_4	1122621.ATZA01000045_gene3568	6.39e-178	570.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1IRFK@117747|Sphingobacteriia	976|Bacteroidetes	M	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD1_k127_1284837_1	471854.Dfer_4223	0.0	1177.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_1284837_5	1122605.KB893646_gene71	2.637e-98	325.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1IP93@117747|Sphingobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD1_k127_1284837_2	925409.KI911562_gene1082	0.0	1035.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
HKD1_k127_1284837_3	700598.Niako_6046	0.0	1031.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD1_k127_1284837_6	700598.Niako_6048	4.474e-90	301.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1ISUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
HKD1_k127_1284837_8	929562.Emtol_0926	2.241e-31	126.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia	976|Bacteroidetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_128799_1	485918.Cpin_5948	3.186e-61	214.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1IQ3K@117747|Sphingobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HKD1_k127_128799_0	1122605.KB893645_gene1011	1.058e-189	606.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
HKD1_k127_1297178_2	558152.IQ37_15395	2.389e-12	73.0	2C1KT@1|root,33DVE@2|Bacteria,4NY76@976|Bacteroidetes,1IBMF@117743|Flavobacteriia,3ZS1I@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1297178_0	1122605.KB893637_gene3111	1.144e-211	677.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1ISVQ@117747|Sphingobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
HKD1_k127_1297178_1	700598.Niako_0824	3.726e-125	421.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
HKD1_k127_1303549_1	153721.MYP_3911	5.641e-182	592.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,47M43@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
HKD1_k127_1303549_0	700598.Niako_6428	4.619e-214	670.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
HKD1_k127_1303549_3	700598.Niako_6429	1.147e-50	185.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1IYMM@117747|Sphingobacteriia	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1303549_2	700598.Niako_6430	6.819e-99	326.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
HKD1_k127_1315180_0	1123248.KB893315_gene3185	7.534e-247	769.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD1_k127_1315180_2	1233950.IW22_09075	7.846e-51	183.0	COG3602@1|root,COG3602@2|Bacteria,4NQ4T@976|Bacteroidetes,1I2YS@117743|Flavobacteriia,3ZS0W@59732|Chryseobacterium	976|Bacteroidetes	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7
HKD1_k127_1315180_1	1107311.Q767_03980	1.328e-56	199.0	2DPIZ@1|root,332A8@2|Bacteria,4P763@976|Bacteroidetes,1IBYP@117743|Flavobacteriia	976|Bacteroidetes	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
HKD1_k127_1315180_4	1163409.UUA_08476	3.059e-08	64.0	2EGGB@1|root,33A8B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1315180_5	760192.Halhy_0505	0.000729	44.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HKD1_k127_1315180_3	925409.KI911562_gene792	1.169e-22	108.0	COG2335@1|root,COG2335@2|Bacteria,4NW3U@976|Bacteroidetes,1IUQQ@117747|Sphingobacteriia	976|Bacteroidetes	M	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
HKD1_k127_1317163_1	1348583.ATLH01000022_gene2343	3.396e-59	221.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia,1F92U@104264|Cellulophaga	976|Bacteroidetes	P	TonB dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_1317163_2	1123248.KB893314_gene3609	5.763e-54	194.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,1J0E7@117747|Sphingobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
HKD1_k127_1317163_0	700598.Niako_6863	5.053e-271	839.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HKD1_k127_1332019_4	1121097.JCM15093_1927	1.955e-20	100.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,2FMC1@200643|Bacteroidia,4AKDR@815|Bacteroidaceae	976|Bacteroidetes	G	COG NOG04984 non supervised orthologous group	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
HKD1_k127_1332019_5	1123248.KB893314_gene3551	1.861e-14	78.0	2CFVU@1|root,3373K@2|Bacteria,4NX7Q@976|Bacteroidetes,1J165@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1332019_2	700598.Niako_0975	2.074e-56	208.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD1_k127_1332019_0	1123276.KB893290_gene5274	7.689e-102	343.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47NMH@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
HKD1_k127_1332019_1	1169152.AXVD01000023_gene3256	2.431e-67	239.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_1332019_3	485918.Cpin_5492	1.042e-29	119.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_133350_0	700598.Niako_6049	4.014e-186	584.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD1_k127_133350_1	1123248.KB893331_gene3804	2.128e-179	578.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
HKD1_k127_1335959_2	143224.JQMD01000002_gene3435	2.139e-27	113.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD1_k127_1335959_0	1288494.EBAPG3_22820	6.999e-96	318.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2W9JB@28216|Betaproteobacteria,372JF@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
HKD1_k127_1335959_1	929556.Solca_0722	2.457e-74	256.0	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,1INV4@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
HKD1_k127_1367959_4	1406840.Q763_11355	2.463e-55	198.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia,2NSQI@237|Flavobacterium	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
HKD1_k127_1367959_0	1122605.KB893647_gene293	1.108e-196	620.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1IQ1H@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
HKD1_k127_1367959_1	929713.NIASO_18155	2.491e-167	529.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD1_k127_1367959_2	700598.Niako_6975	2.514e-104	343.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HKD1_k127_1367959_3	1122605.KB893647_gene311	1.17e-56	199.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1ISUE@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD1_k127_1371794_1	700598.Niako_4414	2.067e-38	147.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IYEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HKD1_k127_1371794_2	485918.Cpin_2328	1.268e-28	120.0	COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes	976|Bacteroidetes	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD1_k127_1371794_0	700598.Niako_4412	0.0	1051.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
HKD1_k127_1372140_0	504472.Slin_2521	3.539e-294	914.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,47NHJ@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
HKD1_k127_1372140_1	886377.Murru_3015	4.507e-62	224.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1I08M@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_1372140_2	1101188.KI912155_gene3092	9.053e-13	74.0	COG1960@1|root,COG1960@2|Bacteria,2GMKM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
HKD1_k127_1413949_1	700598.Niako_6693	2.396e-222	697.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
HKD1_k127_1413949_0	504472.Slin_6142	4.487e-309	968.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,47N1T@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_1413949_4	1408473.JHXO01000009_gene3254	6.578e-80	269.0	COG0454@1|root,COG0456@2|Bacteria,4NMCW@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_1413949_2	1123248.KB893381_gene1080	5.551e-148	473.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1IUE3@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD1_k127_1413949_3	1086011.HJ01_00729	1.683e-119	390.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia,2NYA0@237|Flavobacterium	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	malL	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HKD1_k127_1445308_3	700598.Niako_5823	3.067e-85	294.0	COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,4NEIS@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_1445308_7	700598.Niako_5130	2.247e-24	113.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_1445308_5	313606.M23134_03514	2.234e-52	193.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
HKD1_k127_1445308_8	1122225.AULQ01000006_gene1043	1.808e-19	93.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,1I2TV@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome cbb3 oxidase maturation protein CcoH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
HKD1_k127_1445308_2	929556.Solca_1394	2.817e-172	552.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
HKD1_k127_1445308_4	929556.Solca_1393	1.854e-65	234.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
HKD1_k127_1445308_10	688270.Celal_1945	1.869e-12	69.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia,1F9N3@104264|Cellulophaga	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
HKD1_k127_1445308_0	1279009.ADICEAN_00451	0.0	1124.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
HKD1_k127_1445308_9	929556.Solca_1390	1.765e-13	71.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
HKD1_k127_1445308_1	929556.Solca_1389	3.159e-270	854.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_1445308_6	1150600.ADIARSV_0356	3.697e-29	120.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
HKD1_k127_1451196_0	1202532.FF52_15697	2.207e-149	484.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium	976|Bacteroidetes	S	COG NOG10142 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1451196_1	1239962.C943_00135	8.972e-66	236.0	COG3338@1|root,COG3338@2|Bacteria,4NK9J@976|Bacteroidetes,47SK9@768503|Cytophagia	976|Bacteroidetes	P	Eukaryotic-type carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
HKD1_k127_1451196_2	1198114.AciX9_0562	7.506e-60	207.0	COG1917@1|root,COG1917@2|Bacteria,3Y4HX@57723|Acidobacteria,2JJ92@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_1460131_1	700598.Niako_4696	5.804e-164	520.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD1_k127_1460131_4	925409.KI911562_gene6	6.783e-70	238.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1ISHA@117747|Sphingobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HKD1_k127_1460131_3	1122605.KB893648_gene3597	4.259e-80	269.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HKD1_k127_1460131_0	929713.NIASO_01390	0.0	1294.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD1_k127_1460131_5	700598.Niako_4484	1.528e-58	214.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1IY3C@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
HKD1_k127_1460131_2	1123277.KB893239_gene1227	9.007e-84	280.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,47M8B@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
HKD1_k127_1479658_0	929703.KE386491_gene4114	2.102e-294	914.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
HKD1_k127_1502433_3	938709.AUSH02000011_gene1164	2.778e-113	371.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes	976|Bacteroidetes	I	PFAM PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_1502433_2	929713.NIASO_13905	4.157e-130	424.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
HKD1_k127_1502433_4	1123248.KB893333_gene2817	3.085e-110	364.0	28K2C@1|root,2Z9RQ@2|Bacteria,4NJP3@976|Bacteroidetes,1ITQ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1502433_0	700598.Niako_6694	5.575e-246	769.0	COG0671@1|root,COG0671@2|Bacteria,4NGYP@976|Bacteroidetes,1IR1B@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_1502433_1	700598.Niako_1336	2.839e-180	570.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,1IVK3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
HKD1_k127_1502433_5	700598.Niako_6693	4.673e-76	261.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
HKD1_k127_150257_5	925409.KI911562_gene1891	2.092e-26	109.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HKD1_k127_150257_0	700598.Niako_0113	0.0	1209.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
HKD1_k127_150257_1	929562.Emtol_0758	2.095e-219	705.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD1_k127_150257_4	1121957.ATVL01000012_gene650	5.881e-46	176.0	COG5266@1|root,COG5266@2|Bacteria,4NQ8X@976|Bacteroidetes,47QXS@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
HKD1_k127_150257_2	700598.Niako_0139	3.356e-131	422.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD1_k127_150257_3	700598.Niako_0140	1.735e-83	280.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD1_k127_1531177_0	1123248.KB893326_gene1472	3.34e-270	837.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_1531177_1	700598.Niako_2585	5.134e-144	461.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HKD1_k127_1531177_4	452637.Oter_1641	1.376e-28	120.0	2CCSR@1|root,32RWC@2|Bacteria,46WYJ@74201|Verrucomicrobia,3K9ZP@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_1531177_2	929713.NIASO_06195	9.413e-125	405.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1IQKP@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD1_k127_1531177_3	700598.Niako_2583	8.721e-112	368.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HKD1_k127_153526_2	935863.AWZR01000006_gene1395	2.586e-44	163.0	COG2610@1|root,COG2610@2|Bacteria,1MUFG@1224|Proteobacteria,1RNGE@1236|Gammaproteobacteria,1X6RR@135614|Xanthomonadales	135614|Xanthomonadales	EG	GntP family permease	-	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
HKD1_k127_153526_3	330779.Saci_0923	0.0002845	49.0	COG0346@1|root,arCOG02706@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD1_k127_153526_0	700598.Niako_7230	2.078e-116	385.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD1_k127_153526_1	746697.Aeqsu_0432	1.537e-52	190.0	COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,1IIN1@117743|Flavobacteriia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_153750_8	1123276.KB893254_gene3474	9.492e-13	74.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD1_k127_153750_5	468059.AUHA01000002_gene709	5.316e-108	354.0	COG0708@1|root,COG0708@2|Bacteria,4NF57@976|Bacteroidetes,1IW1J@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD1_k127_153750_6	269798.CHU_2554	3.051e-50	182.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,47R8X@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_153750_0	929713.NIASO_16750	2.173e-223	695.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD1_k127_153750_4	743722.Sph21_0079	8.816e-134	438.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
HKD1_k127_153750_1	1123248.KB893348_gene233	7.4e-207	650.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_153750_2	925409.KI911562_gene442	1.123e-187	595.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_153750_7	700598.Niako_6451	3.225e-30	123.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1ITMU@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
HKD1_k127_153750_3	929713.NIASO_14415	5.824e-151	480.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD1_k127_1543084_3	700598.Niako_1623	4.695e-23	102.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD1_k127_1543084_2	1267211.KI669560_gene2004	1.352e-78	267.0	COG4399@1|root,COG4399@2|Bacteria,4NIDM@976|Bacteroidetes,1IZQF@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD1_k127_1543084_0	700598.Niako_2637	2.264e-109	366.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1IWXG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_1543084_1	700598.Niako_2638	2.784e-82	280.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HKD1_k127_1550375_0	925409.KI911562_gene2246	1.437e-313	965.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
HKD1_k127_1550375_3	1300143.CCAV010000001_gene1472	1.629e-08	64.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes,1I723@117743|Flavobacteriia,3ZSAX@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1550375_1	929713.NIASO_08720	1.876e-196	620.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,1IQFM@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
HKD1_k127_1550375_2	491205.JARQ01000006_gene2865	4.677e-17	87.0	2AA3K@1|root,30ZCD@2|Bacteria,4NN37@976|Bacteroidetes,1I1RV@117743|Flavobacteriia,3ZTWK@59732|Chryseobacterium	976|Bacteroidetes	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
HKD1_k127_1558377_3	485918.Cpin_1090	6.125e-10	60.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1IQAV@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_1558377_0	1107311.Q767_02060	1.025e-161	514.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1HYF4@117743|Flavobacteriia,2NT18@237|Flavobacterium	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
HKD1_k127_1558377_1	794903.OPIT5_28470	2.441e-106	352.0	COG1682@1|root,COG1682@2|Bacteria,46SNF@74201|Verrucomicrobia,3K7TY@414999|Opitutae	414999|Opitutae	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
HKD1_k127_1558377_2	156889.Mmc1_2424	5.079e-32	128.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2VF2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_1581869_4	649349.Lbys_1398	9.21e-34	131.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47KCJ@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
HKD1_k127_1581869_1	1406840.Q763_03960	2.45e-163	519.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,1HZ2C@117743|Flavobacteriia,2P040@237|Flavobacterium	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD1_k127_1581869_2	468059.AUHA01000004_gene2377	4.462e-116	377.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_1581869_0	1123248.KB893336_gene2833	1.638e-189	598.0	COG3391@1|root,COG3391@2|Bacteria,4NHHU@976|Bacteroidetes,1IW3W@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1581869_3	468059.AUHA01000005_gene2447	1.2e-63	228.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1IRY3@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_1581869_5	1077972.ARGLB_113_00660	4.15e-11	64.0	COG3631@1|root,COG3631@2|Bacteria,2IJ9D@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
HKD1_k127_1587593_0	700598.Niako_1020	5.263e-233	728.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
HKD1_k127_1587593_1	700598.Niako_1018	3.521e-34	138.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD1_k127_159402_1	1185876.BN8_06513	4.03e-83	290.0	COG2114@1|root,COG2114@2|Bacteria,4NR9E@976|Bacteroidetes,47V42@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Guanylate_cyc
HKD1_k127_159402_2	1121859.KB890759_gene1894	3.45e-49	182.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_159402_0	926549.KI421517_gene2244	1.416e-212	690.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
HKD1_k127_159402_3	694427.Palpr_2726	9.051e-36	138.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia,22VY6@171551|Porphyromonadaceae	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD1_k127_159750_4	1122605.KB893625_gene2230	1.699e-27	112.0	COG5512@1|root,COG5512@2|Bacteria,4P9X5@976|Bacteroidetes,1IUES@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
HKD1_k127_159750_5	1267211.KI669560_gene1753	1.097e-20	97.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_159750_1	1122605.KB893643_gene858	9.644e-115	381.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD1_k127_159750_2	929713.NIASO_04665	1.336e-76	261.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1IRWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
HKD1_k127_159750_0	1123248.KB893325_gene1164	2.03e-115	378.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD1_k127_159750_3	929713.NIASO_04645	1.016e-42	168.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N,Rhodanese
HKD1_k127_1600063_5	869213.JCM21142_41395	3.59e-13	71.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD1_k127_1600063_2	869213.JCM21142_41394	1.828e-122	396.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD1_k127_1600063_1	869213.JCM21142_41393	1.368e-122	401.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,4NGUP@976|Bacteroidetes	976|Bacteroidetes	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
HKD1_k127_1600063_4	1121373.KB903654_gene1701	4.56e-51	190.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
HKD1_k127_1600063_3	1492737.FEM08_00480	7.572e-55	201.0	2DBBT@1|root,2Z8AC@2|Bacteria,4NIRZ@976|Bacteroidetes,1HZMZ@117743|Flavobacteriia,2NWUU@237|Flavobacterium	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
HKD1_k127_1600063_0	1237149.C900_02493	1.493e-136	445.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD1_k127_1602276_1	700598.Niako_1117	4.015e-210	670.0	COG3291@1|root,COG3291@2|Bacteria,4NV8C@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
HKD1_k127_1602276_0	1122605.KB893644_gene1367	1.021e-248	777.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
HKD1_k127_1602276_2	700598.Niako_5093	2.955e-104	353.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,1IXG6@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
HKD1_k127_1602276_3	929713.NIASO_19330	5.107e-59	211.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1IXNU@117747|Sphingobacteriia	976|Bacteroidetes	I	Ndr family	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_1603952_4	1492738.FEM21_02140	8.108e-11	62.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia,2NUZN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1603952_0	1450525.JATV01000001_gene2652	3.532e-42	157.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia,2NUZN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1603952_3	1453498.LG45_05565	1.174e-16	83.0	COG2827@1|root,COG2827@2|Bacteria,4NVHC@976|Bacteroidetes,1I6FV@117743|Flavobacteriia,2NXFN@237|Flavobacterium	976|Bacteroidetes	L	Excinuclease ABC subunit C	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD1_k127_1603952_1	1123057.P872_13900	2.642e-41	157.0	COG1943@1|root,COG1943@2|Bacteria,4NNQJ@976|Bacteroidetes,47PWF@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD1_k127_1603952_2	1121104.AQXH01000001_gene2090	7.642e-38	145.0	COG3324@1|root,COG3324@2|Bacteria,4NSBC@976|Bacteroidetes	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD1_k127_1610195_0	925409.KI911562_gene1450	5.949e-123	398.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD1_k127_1610195_1	485918.Cpin_0385	7.454e-73	256.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1IPAT@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
HKD1_k127_1610195_2	204773.HEAR3053	1.832e-34	136.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,474CX@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HKD1_k127_1610195_3	700598.Niako_5705	6.609e-08	57.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1ITHJ@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_1612380_3	1122605.KB893646_gene152	1.755e-131	422.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD1_k127_1612380_0	700598.Niako_6288	0.0	1178.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD1_k127_1612380_5	929562.Emtol_0756	7.31e-70	239.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,47PW5@768503|Cytophagia	976|Bacteroidetes	G	MGS-like domain	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD1_k127_1612380_1	1122605.KB893626_gene2423	3.062e-189	595.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD1_k127_1612380_7	1122621.ATZA01000001_gene2065	4.912e-37	144.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1ITEI@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
HKD1_k127_1612380_2	1267211.KI669560_gene340	1.147e-145	471.0	COG1914@1|root,COG1914@2|Bacteria,4NH9R@976|Bacteroidetes,1IQ6Q@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD1_k127_1612380_4	925409.KI911562_gene742	5.141e-94	314.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1IP2K@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD1_k127_1612380_6	700598.Niako_1615	8.85e-65	229.0	COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1IQAT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Allophanate hydrolase subunit 2	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HKD1_k127_1613526_1	700598.Niako_2927	1.218e-94	317.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1ISRE@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD1_k127_1613526_0	700598.Niako_2926	3.229e-264	823.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD1_k127_1624187_1	700598.Niako_2922	3.027e-117	381.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1IQK5@117747|Sphingobacteriia	976|Bacteroidetes	H	Sigma-54 interaction domain	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
HKD1_k127_1624187_2	1150600.ADIARSV_2453	2.644e-66	236.0	2EHJH@1|root,32W49@2|Bacteria,4NTI9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1624187_0	485918.Cpin_6574	4.281e-139	450.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HKD1_k127_1624187_3	760192.Halhy_5074	3.626e-66	232.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1IS95@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
HKD1_k127_1624691_2	866536.Belba_1302	1.347e-97	327.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD1_k127_1624691_0	1121875.KB907546_gene2674	2.744e-108	359.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
HKD1_k127_1624691_5	1121875.KB907546_gene2672	1.069e-17	93.0	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1624691_3	866536.Belba_1302	1.653e-93	323.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD1_k127_1624691_1	929556.Solca_2233	5.996e-107	355.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
HKD1_k127_1624691_4	1237149.C900_04326	6.022e-93	321.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD1_k127_1628596_8	925409.KI911562_gene8	1.158e-44	163.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD1_k127_1628596_9	1267211.KI669560_gene1307	2.291e-19	94.0	2EHH8@1|root,33B95@2|Bacteria,4NXPK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1628596_5	700598.Niako_4698	1.044e-74	256.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1IRYX@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HKD1_k127_1628596_4	929713.NIASO_09480	7.807e-85	285.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_1628596_7	700598.Niako_4701	1.194e-53	192.0	COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
HKD1_k127_1628596_3	700598.Niako_4702	2.694e-91	306.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
HKD1_k127_1628596_2	700598.Niako_4703	4.948e-144	458.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
HKD1_k127_1628596_0	700598.Niako_4704	8.274e-212	667.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
HKD1_k127_1628596_6	929713.NIASO_08665	1.659e-66	233.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1628596_1	929713.NIASO_00130	1.019e-185	589.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1IQAZ@117747|Sphingobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
HKD1_k127_1632881_1	925409.KI911562_gene2834	5.598e-160	508.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD1_k127_1632881_0	1122605.KB893625_gene2312	2.791e-169	539.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1IR38@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1632881_2	1123248.KB893348_gene361	5.7e-123	409.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD1_k127_1633479_0	760192.Halhy_4313	5.506e-123	396.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,1IQYW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
HKD1_k127_1633479_2	929713.NIASO_15900	8.735e-65	229.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,1IYJE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
HKD1_k127_1633479_1	760192.Halhy_4312	4.957e-113	371.0	COG2220@1|root,COG2220@2|Bacteria,4PBVG@976|Bacteroidetes,1IZA4@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1661644_0	1122621.ATZA01000012_gene3169	1.099e-26	112.0	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1IXV5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1661644_2	700598.Niako_2403	8.766e-17	82.0	2DP5Z@1|root,330NW@2|Bacteria,4NV0Q@976|Bacteroidetes,1IUKB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1661644_5	1168289.AJKI01000040_gene3161	7.437e-05	47.0	2AD5B@1|root,312TX@2|Bacteria,4PHS9@976|Bacteroidetes,2G1NU@200643|Bacteroidia,3XKG8@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1661644_1	485913.Krac_4762	1.496e-19	95.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Trypsin
HKD1_k127_1661644_4	1443665.JACA01000003_gene594	2.651e-05	54.0	COG1520@1|root,COG2866@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG1520@2|Bacteria,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
HKD1_k127_1662346_2	700598.Niako_4375	4.571e-104	346.0	COG0583@1|root,COG0583@2|Bacteria,4NHTU@976|Bacteroidetes,1IWM3@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_1662346_1	700598.Niako_4376	1.313e-141	460.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD1_k127_1662346_0	1123248.KB893332_gene2278	2.988e-160	513.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_1670358_8	1239962.C943_02988	9.4e-14	74.0	COG4935@1|root,COG4935@2|Bacteria,4NRQR@976|Bacteroidetes,47YIE@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1670358_0	468059.AUHA01000003_gene1712	0.0	1300.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1INV9@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD1_k127_1670358_3	1123248.KB893359_gene2013	4.137e-51	186.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
HKD1_k127_1670358_6	468059.AUHA01000003_gene1717	1.963e-21	98.0	28TBW@1|root,2ZFKC@2|Bacteria,4P6SF@976|Bacteroidetes,1IZM1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1670358_1	468059.AUHA01000003_gene1718	1.069e-305	944.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IWF1@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
HKD1_k127_1670358_2	468059.AUHA01000003_gene1719	6.361e-170	537.0	COG1071@1|root,COG1071@2|Bacteria,4NJMZ@976|Bacteroidetes,1IW7N@117747|Sphingobacteriia	976|Bacteroidetes	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD1_k127_1670358_4	1121324.CLIT_11c02940	9.189e-42	156.0	COG3324@1|root,COG3324@2|Bacteria,1U9T0@1239|Firmicutes,256I7@186801|Clostridia	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD1_k127_1670358_5	1123248.KB893359_gene2014	1.163e-23	103.0	COG3708@1|root,COG3708@2|Bacteria	2|Bacteria	K	glyoxalase III activity	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18,Zn_ribbon_2
HKD1_k127_1670358_7	700598.Niako_2285	4.341e-21	95.0	COG0022@1|root,COG0022@2|Bacteria,4NFYK@976|Bacteroidetes,1IV1S@117747|Sphingobacteriia	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD1_k127_1680045_1	700598.Niako_6746	1.461e-130	434.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
HKD1_k127_1680045_0	1122605.KB893647_gene402	2.037e-137	443.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD1_k127_1680045_2	1239962.C943_04373	3.235e-30	121.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,47K3S@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_1685037_3	700598.Niako_0797	4.082e-23	99.0	COG2080@1|root,COG2080@2|Bacteria,4NPUP@976|Bacteroidetes,1IX8R@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_1685037_2	700598.Niako_0798	5.483e-50	181.0	COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes,1IYK2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
HKD1_k127_1685037_0	1341181.FLJC2902T_22250	1.455e-99	331.0	COG3662@1|root,COG3662@2|Bacteria,4NEYP@976|Bacteroidetes,1HWJP@117743|Flavobacteriia,2NUUE@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
HKD1_k127_1685037_1	1123234.AUKI01000019_gene467	6.077e-91	305.0	28I9R@1|root,2Z8CE@2|Bacteria,4NNRK@976|Bacteroidetes,1I2Q7@117743|Flavobacteriia	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
HKD1_k127_1686919_3	929713.NIASO_06535	3.578e-42	158.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD1_k127_1686919_4	1121481.AUAS01000012_gene293	1.374e-17	82.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47PZB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
HKD1_k127_1686919_0	1123248.KB893316_gene4593	3.471e-168	532.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1IQBU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD1_k127_1686919_2	700598.Niako_4374	3.19e-69	243.0	COG0589@1|root,COG0589@2|Bacteria,4NPYE@976|Bacteroidetes,1ISGK@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_1686919_1	700598.Niako_1568	1.175e-76	257.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD1_k127_1689475_3	1121104.AQXH01000001_gene1194	1.618e-55	199.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_1689475_1	755732.Fluta_1925	1.2e-144	465.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1ICQK@117743|Flavobacteriia,2PBS2@246874|Cryomorphaceae	976|Bacteroidetes	F	DeoC/LacD family aldolase	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD1_k127_1689475_0	700598.Niako_0156	0.0	1388.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_1689475_2	700598.Niako_0157	4.506e-135	438.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1IR43@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_1708611_10	504472.Slin_2680	2.942e-30	126.0	COG2133@1|root,COG3291@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
HKD1_k127_1708611_0	925409.KI911562_gene2503	7.663e-244	760.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
HKD1_k127_1708611_12	1158294.JOMI01000003_gene2714	9.06e-05	49.0	COG3678@1|root,COG3678@2|Bacteria,4NYJD@976|Bacteroidetes,2FX34@200643|Bacteroidia	976|Bacteroidetes	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1708611_4	580332.Slit_1872	3.761e-56	201.0	COG3548@1|root,COG3548@2|Bacteria,1PGBQ@1224|Proteobacteria,2W8V4@28216|Betaproteobacteria,44WNB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_1708611_2	1123248.KB893336_gene2843	7.985e-99	332.0	COG1105@1|root,COG1105@2|Bacteria,4NFZI@976|Bacteroidetes,1IR0I@117747|Sphingobacteriia	976|Bacteroidetes	G	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.11,2.7.1.144	ko:K00917,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD1_k127_1708611_3	1123278.KB893574_gene6180	3.101e-88	300.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,47NT0@768503|Cytophagia	976|Bacteroidetes	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
HKD1_k127_1708611_6	760192.Halhy_2651	5.277e-54	194.0	COG0454@1|root,COG0456@2|Bacteria,4NQSN@976|Bacteroidetes,1ITBC@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_1708611_11	1492737.FEM08_06400	1.644e-16	84.0	COG2010@1|root,COG2010@2|Bacteria,4PCRX@976|Bacteroidetes,1IDAA@117743|Flavobacteriia,2NXVD@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1708611_1	700598.Niako_4358	2.204e-144	468.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD1_k127_1708611_7	1123248.KB893325_gene1138	4.316e-46	169.0	2E3B3@1|root,32YAM@2|Bacteria,4NW81@976|Bacteroidetes,1ITTZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
HKD1_k127_1708611_8	700598.Niako_2158	7.585e-46	170.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_1708611_9	929713.NIASO_09425	4.935e-31	123.0	COG4281@1|root,COG4281@2|Bacteria,4NVK0@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-coA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
HKD1_k127_1708611_5	762903.Pedsa_1215	1.151e-55	209.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1ITV6@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_1708611_13	593750.Metfor_1413	0.0004008	52.0	COG2244@1|root,arCOG02209@2157|Archaea,2XZTW@28890|Euryarchaeota,2NAHB@224756|Methanomicrobia	224756|Methanomicrobia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HKD1_k127_1716071_3	1123277.KB893239_gene1227	1.175e-108	354.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,47M8B@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
HKD1_k127_1716071_1	761193.Runsl_0202	1.618e-147	473.0	COG0176@1|root,COG2905@1|root,COG0176@2|Bacteria,COG2905@2|Bacteria,4NIUX@976|Bacteroidetes,47KKQ@768503|Cytophagia	976|Bacteroidetes	GT	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,TAL_FSA
HKD1_k127_1716071_5	1123277.KB893239_gene1226	5.866e-63	224.0	COG1778@1|root,COG1778@2|Bacteria,4NMFZ@976|Bacteroidetes,47PAE@768503|Cytophagia	976|Bacteroidetes	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
HKD1_k127_1716071_4	761193.Runsl_3684	2.205e-88	297.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HKD1_k127_1716071_0	925409.KI911562_gene2954	1.618e-181	570.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1IQ61@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD1_k127_1716071_2	1123248.KB893315_gene3002	6.252e-131	430.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1INVF@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD1_k127_172402_3	1123248.KB893326_gene1293	6.509e-201	634.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD1_k127_172402_4	1131812.JQMS01000001_gene413	2.218e-192	611.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD1_k127_172402_0	1406840.Q763_15640	1e-222	700.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
HKD1_k127_172402_1	925409.KI911562_gene327	2.357e-222	702.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2329)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
HKD1_k127_172402_2	485918.Cpin_6279	6.427e-207	651.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD1_k127_172402_5	929562.Emtol_1716	1.941e-154	499.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD1_k127_172402_6	925409.KI911562_gene328	2.518e-109	364.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IQRK@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD1_k127_1746275_2	1121904.ARBP01000009_gene4173	2.51e-15	80.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_1746275_0	743722.Sph21_1179	1.215e-215	695.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IVBV@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_1746275_1	700598.Niako_5205	3.472e-186	594.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IV3C@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_1772130_2	1123248.KB893337_gene2525	2.837e-96	322.0	COG1538@1|root,COG1538@2|Bacteria,4NDZ6@976|Bacteroidetes,1IRPV@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_1772130_1	1123248.KB893337_gene2526	5.361e-148	476.0	COG1566@1|root,COG1566@2|Bacteria,4NEQJ@976|Bacteroidetes,1IQSU@117747|Sphingobacteriia	976|Bacteroidetes	V	secretion protein HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD1_k127_1772130_0	1123248.KB893337_gene2527	2.641e-252	787.0	COG0477@1|root,COG2814@2|Bacteria,4NG27@976|Bacteroidetes,1J0KQ@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
HKD1_k127_1772130_3	485918.Cpin_4745	9.265e-58	216.0	COG1835@1|root,COG1835@2|Bacteria,4NNXT@976|Bacteroidetes,1IUGI@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_1774545_2	700598.Niako_2002	1.099e-19	94.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1IRZA@117747|Sphingobacteriia	976|Bacteroidetes	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD1_k127_1774545_0	700598.Niako_2003	1.545e-101	340.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1IQH7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Integral membrane protein DUF95	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
HKD1_k127_1774545_1	1166018.FAES_1116	8.88e-20	98.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,47PV1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
HKD1_k127_1781360_1	1122137.AQXF01000003_gene2214	1.181e-142	463.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD1_k127_1781360_0	700598.Niako_5129	1.644e-216	680.0	COG0560@1|root,COG1215@1|root,COG0560@2|Bacteria,COG1215@2|Bacteria,4NHAG@976|Bacteroidetes,1IVDW@117747|Sphingobacteriia	976|Bacteroidetes	EM	Putative Phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
HKD1_k127_1781360_2	700598.Niako_5130	2.19e-76	260.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_1793231_1	1048983.EL17_15415	3.221e-67	243.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD1_k127_1793231_0	632518.Calow_1893	3.022e-73	256.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,42FUG@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_1822990_0	468059.AUHA01000002_gene724	2.965e-255	802.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1IR5Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_1822990_1	471854.Dfer_5710	6.369e-87	295.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
HKD1_k127_1826177_7	1121904.ARBP01000060_gene1918	5.067e-81	271.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47JGE@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_1826177_6	760192.Halhy_6117	1.161e-127	413.0	COG0726@1|root,COG0726@2|Bacteria,4NJK7@976|Bacteroidetes,1IS5R@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0726 xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_1826177_3	1408473.JHXO01000005_gene1541	3.324e-251	782.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes,2G2XU@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HKD1_k127_1826177_0	1123248.KB893315_gene3227	0.0	1375.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1IPQY@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
HKD1_k127_1826177_5	1185876.BN8_00699	9.919e-169	534.0	COG1063@1|root,COG1063@2|Bacteria,4NHCK@976|Bacteroidetes,47K5V@768503|Cytophagia	976|Bacteroidetes	E	alcohol dehydrogenase	yjjN	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HKD1_k127_1826177_1	714943.Mucpa_1149	1.977e-315	976.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,1IPKM@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG2382 Enterochelin esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
HKD1_k127_1826177_4	700598.Niako_0709	1.386e-224	706.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1IP52@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HKD1_k127_1826177_2	929562.Emtol_2751	5.193e-269	834.0	COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,47N9J@768503|Cytophagia	976|Bacteroidetes	E	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD1_k127_1826177_8	1185876.BN8_00788	1.45e-75	255.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
HKD1_k127_1829066_0	1265505.ATUG01000002_gene1197	3.675e-125	408.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2MJS8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD1_k127_1829066_1	1396141.BATP01000002_gene4802	5.483e-38	147.0	COG0387@1|root,COG0387@2|Bacteria,46UPT@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
HKD1_k127_1872875_5	509635.N824_20005	2.352e-33	128.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,1IQYR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD1_k127_1872875_0	1089547.KB913013_gene4649	6.873e-216	691.0	COG4886@1|root,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47P4Q@768503|Cytophagia	976|Bacteroidetes	S	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
HKD1_k127_1872875_2	509635.N824_20010	3.406e-132	429.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1IQ1F@117747|Sphingobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
HKD1_k127_1872875_4	649747.HMPREF0083_02901	3.07e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,1V3W3@1239|Firmicutes,4HHYX@91061|Bacilli,26Y5A@186822|Paenibacillaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_1872875_1	700598.Niako_6347	2.824e-157	504.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1INUK@117747|Sphingobacteriia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD1_k127_1872875_3	929713.NIASO_09420	9.911e-80	287.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,1IUQ8@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
HKD1_k127_1888240_0	1178825.ALIH01000013_gene518	5.381e-183	582.0	COG2067@1|root,COG2067@2|Bacteria,4PFMQ@976|Bacteroidetes,1HYJE@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
HKD1_k127_1888240_2	202698.XP_007388773.1	4.899e-12	78.0	KOG1130@1|root,KOG1130@2759|Eukaryota,38BEC@33154|Opisthokonta,3PEWK@4751|Fungi,3V5S6@5204|Basidiomycota,22F6I@155619|Agaricomycetes,3H8UT@355688|Agaricomycetes incertae sedis	4751|Fungi	T	TPR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12
HKD1_k127_1888240_1	1166018.FAES_2381	4.571e-126	411.0	COG2303@1|root,COG2303@2|Bacteria,4NFEH@976|Bacteroidetes,47NGG@768503|Cytophagia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
HKD1_k127_1898093_1	700598.Niako_0991	7.861e-266	823.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD1_k127_1898093_2	1239962.C943_00888	1.792e-32	130.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,47RAK@768503|Cytophagia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD1_k127_1898093_3	929562.Emtol_0844	4.384e-06	53.0	2AXFQ@1|root,31PF8@2|Bacteria,4NQN3@976|Bacteroidetes,47SZR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1898093_0	700598.Niako_0988	3.888e-290	897.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1IVXH@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD1_k127_1900303_4	1122605.KB893637_gene3103	7.414e-46	174.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HKD1_k127_1900303_0	700598.Niako_1024	0.0	1862.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD1_k127_1900303_3	1122605.KB893625_gene1861	3.61e-57	199.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_1900303_1	925409.KI911562_gene2365	2.815e-204	642.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,1IQGY@117747|Sphingobacteriia	976|Bacteroidetes	G	Nucleoside	nupG	-	-	ko:K03289,ko:K11537	-	-	-	-	ko00000,ko02000	2.A.1.10.1,2.A.1.10.2	-	-	Nuc_H_symport
HKD1_k127_1900303_2	471854.Dfer_0319	1.548e-69	249.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
HKD1_k127_1948963_2	700598.Niako_2074	8.865e-24	102.0	2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1948963_0	929703.KE386491_gene2330	3.159e-144	468.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD1_k127_1948963_1	925409.KI911562_gene2428	3.661e-136	437.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1IV68@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
HKD1_k127_19582_1	1122605.KB893626_gene2365	2.834e-71	243.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD1_k127_19582_3	1270196.JCKI01000002_gene356	2.806e-29	121.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes,1ITWM@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_19582_0	925409.KI911562_gene821	4.309e-122	396.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,1IQ46@117747|Sphingobacteriia	976|Bacteroidetes	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
HKD1_k127_19582_2	411477.PARMER_02548	8.046e-61	215.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia,22X88@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glycosyl transferase family group 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
HKD1_k127_1988407_0	1123248.KB893359_gene2201	2.147e-286	884.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD1_k127_2006107_2	929713.NIASO_00350	2.01e-16	79.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1IPTE@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
HKD1_k127_2006107_0	700598.Niako_5042	2.104e-189	599.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1IP4Q@117747|Sphingobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD1_k127_2006107_1	1408433.JHXV01000016_gene1822	1.74e-16	86.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBB7@246874|Cryomorphaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD1_k127_2026956_4	700598.Niako_1536	1.277e-75	255.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
HKD1_k127_2026956_1	700598.Niako_1990	4.043e-109	361.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1IPJH@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD1_k127_2026956_2	1123248.KB893348_gene336	5.762e-80	270.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
HKD1_k127_2026956_0	485918.Cpin_5957	4.19e-206	651.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
HKD1_k127_2026956_3	925409.KI911562_gene1786	2.428e-78	265.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,1IRXH@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
HKD1_k127_2026956_5	714943.Mucpa_3255	1.671e-65	233.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
HKD1_k127_2026956_6	700598.Niako_1983	8.53e-52	185.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
HKD1_k127_2044452_0	1267211.KI669560_gene730	6.852e-193	607.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1IRA1@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD1_k127_2044452_3	700598.Niako_6536	1.466e-27	112.0	2BTNY@1|root,32NVY@2|Bacteria,4NV0G@976|Bacteroidetes,1IUM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
HKD1_k127_2044452_1	694427.Palpr_1487	4.815e-132	429.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,2FMH5@200643|Bacteroidia,22X85@171551|Porphyromonadaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD1_k127_2044452_2	1131812.JQMS01000001_gene948	9.368e-78	264.0	COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,1IE7S@117743|Flavobacteriia,2NY3G@237|Flavobacterium	976|Bacteroidetes	S	Pfam Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_2064117_0	700598.Niako_0290	7.325e-138	443.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD1_k127_2064117_2	700598.Niako_0289	5.27e-42	160.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1ITEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD1_k127_2064117_3	700598.Niako_0288	2.153e-41	156.0	2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,1ISW4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD1_k127_2064117_1	929713.NIASO_09580	2.79e-44	162.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_2075880_0	1267211.KI669560_gene1234	5.917e-139	453.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia	976|Bacteroidetes	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD1_k127_2075880_3	700598.Niako_7361	6.554e-21	102.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2075880_2	700598.Niako_7362	6.148e-45	169.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1IUCJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Phosphoesterase, HXTX	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD1_k127_2075880_4	1278073.MYSTI_07110	4.001e-06	54.0	COG4206@1|root,COG4206@2|Bacteria,1QX9A@1224|Proteobacteria	1224|Proteobacteria	H	Carboxypeptidase regulatory-like domain	oar1	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD1_k127_2075880_1	925409.KI911562_gene1482	1.727e-126	409.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1IRN3@117747|Sphingobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
HKD1_k127_2083165_2	700598.Niako_0135	1.832e-63	218.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD1_k127_2083165_1	700598.Niako_0134	3.299e-128	419.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1IXHP@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD1_k127_2083165_3	1121957.ATVL01000007_gene2031	1.09e-53	192.0	2E373@1|root,32Y6V@2|Bacteria,4NWZF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2083165_4	700598.Niako_0132	1.868e-48	183.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,1IYK8@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
HKD1_k127_2083165_0	1122605.KB893636_gene3465	0.0	1038.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HKD1_k127_2083165_5	700598.Niako_0128	1.8e-15	76.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD1_k127_20935_2	1122621.ATZA01000001_gene1933	1.767e-37	143.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HKD1_k127_20935_0	929556.Solca_4228	5.971e-147	478.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1IQ33@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HKD1_k127_20935_1	700598.Niako_2008	1.786e-46	169.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
HKD1_k127_210021_0	925409.KI911562_gene2249	1.009e-188	592.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,1INSE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD1_k127_210021_2	929703.KE386491_gene3813	0.0004037	52.0	2E7W0@1|root,332AS@2|Bacteria,4NPQ3@976|Bacteroidetes,47QYZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_210021_1	1123276.KB893251_gene3597	1.227e-46	176.0	arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,47RY3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2111375_0	929556.Solca_0330	1.848e-165	538.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IPPS@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
HKD1_k127_2111375_1	1189612.A33Q_2985	4.063e-129	424.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_2111375_2	313595.P700755_000330	0.0005809	42.0	COG1943@1|root,COG1943@2|Bacteria,4NTG8@976|Bacteroidetes,1I47T@117743|Flavobacteriia	976|Bacteroidetes	L	SPTR Genome sequencing data, contig C243	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD1_k127_2118488_2	1296416.JACB01000036_gene2885	8.253e-47	175.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,1I2B0@117743|Flavobacteriia,2YHB3@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
HKD1_k127_2118488_5	1123248.KB893359_gene2173	2.238e-18	87.0	2EMPS@1|root,33FC7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2118488_3	700598.Niako_5664	9.269e-45	165.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1J0KN@117747|Sphingobacteriia	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
HKD1_k127_2118488_1	485918.Cpin_0423	1.66e-62	221.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1IXH3@117747|Sphingobacteriia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2118488_0	1122605.KB893647_gene424	8.406e-315	987.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD1_k127_2118488_4	926556.Echvi_2895	2.257e-32	135.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2125885_1	926562.Oweho_3372	1.95e-38	153.0	28NYT@1|root,2ZBVV@2|Bacteria,4NPVB@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD1_k127_2125885_0	1338011.BD94_3322	3.882e-97	323.0	COG1208@1|root,COG1208@2|Bacteria,4PM3W@976|Bacteroidetes,1HYFV@117743|Flavobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HKD1_k127_2125885_2	1280663.ATVR01000008_gene2038	2.62e-31	124.0	COG1917@1|root,COG1917@2|Bacteria,1UDHH@1239|Firmicutes,25I8B@186801|Clostridia,4C153@830|Butyrivibrio	186801|Clostridia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2127098_0	1341181.FLJC2902T_24040	8.1e-224	706.0	COG2985@1|root,COG2985@2|Bacteria,4NHM3@976|Bacteroidetes,1IIQ6@117743|Flavobacteriia,2NUWV@237|Flavobacterium	976|Bacteroidetes	U	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
HKD1_k127_2127098_1	1492737.FEM08_01140	1.306e-154	500.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,1HWT3@117743|Flavobacteriia,2NSBP@237|Flavobacterium	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
HKD1_k127_2127098_2	700598.Niako_5413	8.352e-38	145.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2129293_0	925409.KI911562_gene1393	9.307e-131	420.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
HKD1_k127_2129293_2	700598.Niako_6698	1.681e-26	115.0	2EHHG@1|root,33B9E@2|Bacteria,4NXY9@976|Bacteroidetes,1IUFY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2129293_1	1123248.KB893315_gene3036	1.511e-69	241.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_2148707_0	700598.Niako_5505	4.069e-196	627.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
HKD1_k127_2148707_3	925409.KI911562_gene1609	4.092e-75	256.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1ISTD@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD1_k127_2148707_2	700598.Niako_5507	1.009e-97	331.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1IP5H@117747|Sphingobacteriia	976|Bacteroidetes	NU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
HKD1_k127_2148707_4	929713.NIASO_09930	5.501e-59	210.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1IRTF@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
HKD1_k127_2148707_1	925409.KI911562_gene1612	5.359e-161	514.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD1_k127_2155369_8	1500281.JQKZ01000046_gene2616	1.677e-11	66.0	COG0664@1|root,COG0664@2|Bacteria,4NEUF@976|Bacteroidetes,1IFWU@117743|Flavobacteriia,3ZRGG@59732|Chryseobacterium	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_2155369_6	485913.Krac_9564	4.349e-31	130.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_2155369_3	1191523.MROS_1395	4.043e-54	191.0	COG4898@1|root,COG4898@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
HKD1_k127_2155369_2	1341181.FLJC2902T_10920	6.387e-66	228.0	298UU@1|root,2ZVYZ@2|Bacteria,4NPH1@976|Bacteroidetes,1I8RV@117743|Flavobacteriia,2NWGH@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD1_k127_2155369_0	925409.KI911562_gene1330	2.228e-152	486.0	COG0596@1|root,COG0596@2|Bacteria,4NJJD@976|Bacteroidetes,1IWRH@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_2155369_1	929713.NIASO_06860	9.122e-88	291.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,1IS58@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_2155369_5	1123276.KB893290_gene5282	2.583e-48	175.0	COG0640@1|root,COG0640@2|Bacteria,4NQCU@976|Bacteroidetes,47QH4@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD1_k127_2155369_7	700598.Niako_1283	1.822e-23	107.0	2E82X@1|root,34BW2@2|Bacteria,4P6AY@976|Bacteroidetes,1IZ0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2155369_4	861299.J421_1360	8.286e-50	191.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
HKD1_k127_2176936_4	700598.Niako_1585	2.264e-58	209.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes	976|Bacteroidetes	K	(GNAT) family	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_2176936_5	700598.Niako_7012	8.409e-28	126.0	COG1361@1|root,COG4386@1|root,COG1361@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	omcB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Chlam_OMP6,DUF11
HKD1_k127_2176936_2	929713.NIASO_04495	5.966e-189	593.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD1_k127_2176936_0	700598.Niako_1599	1.813e-205	645.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD1_k127_2176936_1	1122605.KB893643_gene707	8.448e-195	619.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HKD1_k127_2176936_3	700598.Niako_1602	4.151e-71	243.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1ITF8@117747|Sphingobacteriia	976|Bacteroidetes	F	cytidine and deoxycytidylate deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD1_k127_2176936_6	1123248.KB893317_gene4289	5.118e-25	104.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1IYID@117747|Sphingobacteriia	976|Bacteroidetes	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD1_k127_2181344_0	700598.Niako_4953	0.0	1382.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
HKD1_k127_2181344_1	1279009.ADICEAN_03016	5.784e-36	155.0	2CV66@1|root,32SWY@2|Bacteria,4NT2K@976|Bacteroidetes,47V7J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2196660_3	1123248.KB893385_gene4911	2.709e-185	588.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IQ6R@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_2196660_0	700598.Niako_4373	1.862e-252	794.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPJF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
HKD1_k127_2196660_2	1123248.KB893385_gene4912	2.026e-186	585.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2196660_4	1123248.KB893385_gene4913	2.856e-127	411.0	COG2120@1|root,COG2120@2|Bacteria,4P03X@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD1_k127_2196660_7	700598.Niako_6519	1.717e-59	212.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_2196660_5	714943.Mucpa_1944	4.603e-124	411.0	COG1538@1|root,COG1538@2|Bacteria,4NE4S@976|Bacteroidetes,1IR82@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_2196660_6	1150600.ADIARSV_3460	2.346e-117	388.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1IU9I@117747|Sphingobacteriia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HKD1_k127_2196660_1	1150600.ADIARSV_3459	5.975e-248	774.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPSY@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD1_k127_2224738_2	1122605.KB893637_gene3406	1.449e-17	82.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
HKD1_k127_2224738_1	929713.NIASO_08835	1.005e-34	134.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1ISVD@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD1_k127_2224738_0	929713.NIASO_08830	2.878e-128	415.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD1_k127_2235384_2	1296415.JACC01000015_gene744	2.6e-34	142.0	COG4403@1|root,COG4403@2|Bacteria,4NJ29@976|Bacteroidetes,1HZUF@117743|Flavobacteriia,2YIVV@290174|Aquimarina	976|Bacteroidetes	V	Lanthionine synthetase C-like protein	-	-	-	ko:K20484	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	LANC_like
HKD1_k127_2235384_0	1123248.KB893359_gene1996	0.0	1343.0	2C4IS@1|root,2Z81U@2|Bacteria,4NETW@976|Bacteroidetes,1IQYA@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lantibiotic dehydratase	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
HKD1_k127_2235384_1	1123248.KB893359_gene1995	2.162e-37	144.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,1IPHA@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	lktB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
HKD1_k127_224287_3	1185876.BN8_01380	2.668e-13	72.0	COG0662@1|root,COG0662@2|Bacteria,4NSGT@976|Bacteroidetes,47RN2@768503|Cytophagia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_224287_1	1166018.FAES_5122	7.263e-193	638.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47XFV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_224287_2	1166018.FAES_5123	1.572e-81	276.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_224287_0	929713.NIASO_20880	1.01e-196	620.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IX27@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_2279941_3	700598.Niako_2014	6.478e-71	249.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1ITG6@117747|Sphingobacteriia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD1_k127_2279941_1	929713.NIASO_02935	0.0	1055.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
HKD1_k127_2279941_4	700598.Niako_1561	7.062e-66	235.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1IYEN@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_2279941_2	700598.Niako_2561	7.322e-170	538.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1IQ9P@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
HKD1_k127_2279941_0	700598.Niako_2562	0.0	1119.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,1IPKN@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	CBM_20,Glyco_hydro_77
HKD1_k127_2279941_5	1131812.JQMS01000001_gene211	4.661e-55	196.0	COG0454@1|root,COG0456@2|Bacteria,4NQ82@976|Bacteroidetes,1I2X6@117743|Flavobacteriia,2NWGA@237|Flavobacterium	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_2279941_6	468059.AUHA01000002_gene1352	1.052e-33	137.0	2E82X@1|root,34BW2@2|Bacteria,4P6AY@976|Bacteroidetes,1IZ0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2284227_8	880071.Fleli_0885	2.877e-59	216.0	COG0463@1|root,COG0463@2|Bacteria,4P0WQ@976|Bacteroidetes,47YDM@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	2.4.1.293	ko:K17250	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD1_k127_2284227_3	880071.Fleli_3085	4.051e-97	332.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_2284227_4	1279009.ADICEAN_00544	2.303e-96	327.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
HKD1_k127_2284227_2	1122605.KB893647_gene419	6.1e-98	336.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2284227_0	926549.KI421517_gene1707	5.176e-206	658.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HKD1_k127_2284227_5	1423321.AS29_00305	6.634e-92	312.0	COG0726@1|root,COG0726@2|Bacteria,1TQYJ@1239|Firmicutes,4HE94@91061|Bacilli	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_2284227_9	153721.MYP_1022	1.125e-55	205.0	COG0223@1|root,COG0223@2|Bacteria,4NNM5@976|Bacteroidetes	976|Bacteroidetes	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
HKD1_k127_2284227_1	1122605.KB893647_gene420	6.199e-137	446.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_2284227_7	1122605.KB893647_gene421	1.568e-72	252.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD1_k127_2284227_6	700598.Niako_6788	2.254e-73	251.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
HKD1_k127_2291939_1	700598.Niako_5523	4.458e-216	683.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD1_k127_2291939_0	1122605.KB893648_gene3665	1.8e-241	760.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD1_k127_2291939_3	1122605.KB893648_gene3699	2.94e-126	407.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1INYT@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2291939_4	700598.Niako_5516	8.098e-70	239.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1INYT@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2291939_2	1185876.BN8_01016	4.07e-136	445.0	COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,47M8X@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_2291939_6	700598.Niako_0302	2.059e-34	135.0	COG3795@1|root,COG3795@2|Bacteria,4NUTR@976|Bacteroidetes	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD1_k127_2291939_5	700598.Niako_5515	8.441e-45	164.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD1_k127_2304910_1	760192.Halhy_3927	3.177e-183	580.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
HKD1_k127_2304910_0	1166018.FAES_4310	1.498e-238	745.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,47JK0@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HKD1_k127_2310010_0	1270196.JCKI01000004_gene1026	2.281e-172	552.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1IP2N@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein required for spore maturation in B.subtilis	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HKD1_k127_2310010_1	700598.Niako_1212	4.527e-124	400.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD1_k127_23298_6	357276.EL88_16405	5.622e-05	48.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	bioH	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD1_k127_23298_3	1470591.BW41_03339	9.762e-48	175.0	COG3631@1|root,COG3631@2|Bacteria,1N1IW@1224|Proteobacteria,2UGCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD1_k127_23298_4	1121899.Q764_04595	1.026e-38	146.0	COG2350@1|root,COG2350@2|Bacteria,4NVI4@976|Bacteroidetes,1I5WQ@117743|Flavobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD1_k127_23298_0	1121098.HMPREF1534_02018	5.186e-107	355.0	COG0501@1|root,COG0501@2|Bacteria,4PIP6@976|Bacteroidetes,2FPH4@200643|Bacteroidia,4ANR0@815|Bacteroidaceae	976|Bacteroidetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
HKD1_k127_23298_1	269798.CHU_3528	5.976e-70	241.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,47RCD@768503|Cytophagia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD1_k127_23298_5	700598.Niako_1538	6.962e-36	143.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Cupin_2,Cupin_7
HKD1_k127_23298_2	700598.Niako_1539	4.672e-58	206.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD1_k127_2334347_1	1267211.KI669560_gene1537	2.549e-84	281.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes,1J1AE@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_2334347_2	700598.Niako_2089	1.873e-82	276.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1ISRY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_2334347_3	700598.Niako_2088	5.216e-78	264.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_2334347_4	925409.KI911562_gene2102	3.08e-53	191.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
HKD1_k127_2334347_0	925409.KI911562_gene2102	4.09e-127	411.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
HKD1_k127_2334347_5	1341181.FLJC2902T_30430	8.442e-47	171.0	COG2110@1|root,COG2110@2|Bacteria,4NNRH@976|Bacteroidetes,1I2GR@117743|Flavobacteriia,2NWCS@237|Flavobacterium	976|Bacteroidetes	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
HKD1_k127_2344410_0	700598.Niako_6207	6.062e-173	544.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1IVM8@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD1_k127_2344410_2	925409.KI911562_gene1074	1.795e-139	452.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD1_k127_2344410_3	925409.KI911562_gene1075	2.194e-76	260.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1IYNI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
HKD1_k127_2344410_1	1267211.KI669560_gene745	2.804e-147	471.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
HKD1_k127_2344410_5	1120966.AUBU01000005_gene3718	3.866e-29	117.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
HKD1_k127_2344410_6	118173.KB235914_gene2326	1.195e-25	108.0	COG1724@1|root,COG1724@2|Bacteria,1G890@1117|Cyanobacteria,1HC6J@1150|Oscillatoriales	1117|Cyanobacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
HKD1_k127_2344410_4	1123248.KB893331_gene3804	3.515e-63	221.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
HKD1_k127_235730_1	118163.Ple7327_0238	7.674e-54	198.0	COG2242@1|root,COG2242@2|Bacteria,1G6NV@1117|Cyanobacteria	1117|Cyanobacteria	H	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD1_k127_235730_2	398578.Daci_3629	3.972e-24	114.0	COG1835@1|root,COG1835@2|Bacteria,1RICE@1224|Proteobacteria,2VV24@28216|Betaproteobacteria,4AFRU@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_235730_0	1121904.ARBP01000006_gene3964	5.657e-59	210.0	COG1524@1|root,COG3379@1|root,COG1524@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest,TPR_19
HKD1_k127_2359230_1	925409.KI911562_gene105	2.308e-126	411.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_2359230_0	700598.Niako_7323	1.517e-153	493.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD1_k127_2359230_2	1123248.KB893329_gene4488	1.028e-39	148.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD1_k127_2359509_1	929713.NIASO_16760	6.033e-64	224.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
HKD1_k127_2359509_0	700598.Niako_5631	4.336e-238	754.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
HKD1_k127_2375198_2	700598.Niako_6236	9.039e-65	224.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD1_k127_2375198_3	929713.NIASO_15970	2.741e-42	164.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1IUI6@117747|Sphingobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2375198_0	929713.NIASO_15950	1.707e-238	745.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD1_k127_2375198_1	1122605.KB893628_gene4541	3.995e-106	348.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD1_k127_2405503_14	925409.KI911562_gene2835	6.208e-34	132.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1IR48@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD1_k127_2405503_9	700598.Niako_3976	2.572e-75	255.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD1_k127_2405503_7	700598.Niako_4136	2.718e-84	285.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1IS27@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD1_k127_2405503_2	1123248.KB893337_gene2461	4.259e-146	476.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
HKD1_k127_2405503_13	700598.Niako_4138	1.711e-34	134.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,1J0N6@117747|Sphingobacteriia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HKD1_k127_2405503_3	925409.KI911562_gene1987	1.308e-125	407.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD1_k127_2405503_1	700598.Niako_4140	1.311e-153	490.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD1_k127_2405503_5	700598.Niako_4141	1.276e-100	330.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
HKD1_k127_2405503_4	1123248.KB893318_gene4146	7.319e-110	361.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD1_k127_2405503_8	1123248.KB893328_gene877	6.482e-80	269.0	COG2514@1|root,COG2514@2|Bacteria,4NMJC@976|Bacteroidetes,1ISH3@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
HKD1_k127_2405503_11	700598.Niako_0976	3.016e-46	170.0	COG0720@1|root,COG0720@2|Bacteria,4NRT5@976|Bacteroidetes,1IT05@117747|Sphingobacteriia	976|Bacteroidetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD1_k127_2405503_0	485918.Cpin_4031	4.26e-205	644.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1INU3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_2405503_6	700598.Niako_4144	3.953e-100	332.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IX0Z@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
HKD1_k127_2405503_15	398512.JQKC01000055_gene2541	4.219e-08	60.0	2E52N@1|root,301FD@2|Bacteria,1VNBQ@1239|Firmicutes,24VJA@186801|Clostridia	186801|Clostridia	S	SMI1 / KNR4 family	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
HKD1_k127_2405503_10	471854.Dfer_0431	1.776e-65	229.0	COG0664@1|root,COG0664@2|Bacteria,4NNJE@976|Bacteroidetes,47QMS@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_24197_1	700598.Niako_4442	9.645e-186	586.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_24197_5	1538644.KO02_15485	2.013e-39	159.0	28KGE@1|root,2ZA27@2|Bacteria,4NKV3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_24197_3	756499.Desde_0863	4.573e-62	216.0	COG2050@1|root,COG2050@2|Bacteria,1VXYK@1239|Firmicutes,251HM@186801|Clostridia	186801|Clostridia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD1_k127_24197_2	925409.KI911562_gene2871	1.847e-180	573.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD1_k127_24197_7	1279009.ADICEAN_02967	2.264e-24	114.0	COG2010@1|root,COG3291@1|root,COG2010@2|Bacteria,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia	976|Bacteroidetes	C	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_24197_6	925409.KI911562_gene2811	1.192e-25	121.0	COG3266@1|root,COG3266@2|Bacteria,4NKN6@976|Bacteroidetes,1IT2C@117747|Sphingobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD1_k127_24197_4	1237149.C900_01967	2.134e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,47P68@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_24197_0	760192.Halhy_0141	2.977e-196	619.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IWFS@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD1_k127_24197_8	1230343.CANP01000042_gene3124	8.111e-08	53.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_2423327_4	925409.KI911562_gene415	5.819e-84	284.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD1_k127_2423327_7	700598.Niako_4388	1.173e-24	107.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1IUQC@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_2423327_1	929713.NIASO_13400	6.758e-287	887.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD1_k127_2423327_6	1122605.KB893626_gene2783	1.599e-43	167.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,1IU4I@117747|Sphingobacteriia	976|Bacteroidetes	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
HKD1_k127_2423327_0	1123248.KB893348_gene254	0.0	1034.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
HKD1_k127_2423327_3	1122605.KB893647_gene396	3.252e-118	388.0	COG2602@1|root,COG2602@2|Bacteria,4NH11@976|Bacteroidetes,1IYF8@117747|Sphingobacteriia	976|Bacteroidetes	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
HKD1_k127_2423327_2	929713.NIASO_14645	5.244e-229	713.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_2423327_5	700598.Niako_6667	6.929e-74	251.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_2423327_8	925409.KI911562_gene447	1.25e-23	108.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2444976_2	1229487.AMYW01000021_gene1730	1.114e-100	336.0	COG2267@1|root,COG2267@2|Bacteria,4NIGT@976|Bacteroidetes,1I1MM@117743|Flavobacteriia,2P046@237|Flavobacterium	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hydrolase_4
HKD1_k127_2444976_1	1506583.JQJY01000007_gene4109	3.677e-111	371.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZ3N@117743|Flavobacteriia,2NXGC@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_2444976_0	644968.DFW101_1329	8.209e-200	647.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD1_k127_2470758_0	694427.Palpr_1996	1.23e-275	857.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,2FMH3@200643|Bacteroidia,22VYK@171551|Porphyromonadaceae	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA_1	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
HKD1_k127_2470758_1	925409.KI911562_gene2310	2.955e-130	424.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IQXT@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD1_k127_2472129_0	1408813.AYMG01000008_gene4068	1.565e-286	897.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1INQB@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_2473213_2	700598.Niako_5692	3.743e-157	498.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1IQ2H@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD1_k127_2473213_3	700598.Niako_5693	3.281e-116	379.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1IPBE@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD1_k127_2473213_1	700598.Niako_5694	3.498e-173	549.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD1_k127_2473213_4	929713.NIASO_10715	1.218e-38	149.0	29Q4T@1|root,30B3K@2|Bacteria,4NPGB@976|Bacteroidetes	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_2473213_0	1122605.KB893626_gene2645	1.01e-215	676.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
HKD1_k127_2495311_2	929713.NIASO_15465	3.087e-138	443.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD1_k127_2495311_6	1267211.KI669560_gene513	1.301e-37	147.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1ISZQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
HKD1_k127_2495311_7	929713.NIASO_15475	3.824e-23	100.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,1IU0B@117747|Sphingobacteriia	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD1_k127_2495311_5	1267211.KI669560_gene511	1.302e-72	249.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1IRZ1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD1_k127_2495311_1	700598.Niako_6331	7.228e-173	551.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,1INNP@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD1_k127_2495311_0	313606.M23134_05244	2.447e-175	560.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_2495311_3	700598.Niako_6332	4.974e-117	384.0	COG2367@1|root,COG2367@2|Bacteria,4NDYP@976|Bacteroidetes,1INNE@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HKD1_k127_2495311_4	700598.Niako_6415	1.021e-104	345.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD1_k127_25044_0	1123248.KB893359_gene2142	5.591e-83	280.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
HKD1_k127_25044_1	929713.NIASO_10450	2.284e-58	205.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
HKD1_k127_254578_2	1121104.AQXH01000001_gene1910	1.746e-20	98.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_254578_0	700598.Niako_6088	1.399e-197	623.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1IPI0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_254578_1	204669.Acid345_1383	1.124e-117	383.0	2CEY7@1|root,2Z8CG@2|Bacteria,3Y70V@57723|Acidobacteria,2JKPR@204432|Acidobacteriia	204432|Acidobacteriia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_254578_3	1051632.TPY_3362	1.275e-05	47.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WD2K@538999|Clostridiales incertae sedis	186801|Clostridia	C	succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative mitochondrial subgroup	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD1_k127_255886_3	485918.Cpin_4000	1.821e-45	171.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1IPDU@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD1_k127_255886_0	929713.NIASO_17165	3.021e-179	583.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1INPT@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD1_k127_255886_1	1123248.KB893359_gene2066	1.725e-154	492.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
HKD1_k127_255886_2	700598.Niako_0961	4.718e-119	395.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1IQNH@117747|Sphingobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
HKD1_k127_2572228_2	1123248.KB893337_gene2378	1.736e-90	301.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,1IQTR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Xylose	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_2572228_1	1122605.KB893627_gene2900	1.943e-127	416.0	COG2133@1|root,COG2133@2|Bacteria,4PMM3@976|Bacteroidetes	976|Bacteroidetes	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
HKD1_k127_2572228_0	700598.Niako_3528	3.184e-262	811.0	COG0673@1|root,COG0673@2|Bacteria,4NHDS@976|Bacteroidetes,1IQ1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_2581609_0	700598.Niako_1208	5.016e-100	330.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPDG@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD1_k127_2581609_1	1123248.KB893321_gene483	5.417e-85	286.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD1_k127_2640000_1	1267211.KI669560_gene1544	6.484e-85	290.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_2640000_0	929713.NIASO_00145	8.606e-248	769.0	COG0535@1|root,COG0535@2|Bacteria,4NZSZ@976|Bacteroidetes,1IWQT@117747|Sphingobacteriia	976|Bacteroidetes	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD1_k127_2652622_2	485918.Cpin_2331	2.426e-78	263.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD1_k127_2652622_5	1123057.P872_22760	7.134e-21	99.0	COG0406@1|root,COG0406@2|Bacteria,4NQWA@976|Bacteroidetes,47SDA@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD1_k127_2652622_0	700598.Niako_4418	6.738e-110	359.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,1IPIE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2652622_3	1444711.CCJF01000005_gene485	1.542e-61	222.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD1_k127_2652622_1	1122605.KB893645_gene1077	1.152e-105	351.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1IP6X@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_2652622_6	880070.Cycma_4972	2.376e-14	77.0	COG2207@1|root,COG2207@2|Bacteria,4NJNH@976|Bacteroidetes,47QMZ@768503|Cytophagia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HKD1_k127_2652622_4	1317122.ATO12_02845	3.87e-24	105.0	2EGCH@1|root,33A4A@2|Bacteria,4NVXN@976|Bacteroidetes,1I6C2@117743|Flavobacteriia,2YJGZ@290174|Aquimarina	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
HKD1_k127_2658542_0	714943.Mucpa_0328	8.887e-182	579.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPQC@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD1_k127_2658542_1	485918.Cpin_5634	1.834e-138	452.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1IVK9@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HKD1_k127_2658542_3	926549.KI421517_gene2452	1.08e-05	56.0	COG3209@1|root,COG3209@2|Bacteria,4NYRN@976|Bacteroidetes	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2658542_2	1296416.JACB01000010_gene1522	1.139e-68	242.0	COG2834@1|root,COG3391@1|root,COG2834@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1I9S0@117743|Flavobacteriia,2YM4C@290174|Aquimarina	976|Bacteroidetes	M	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,NHL
HKD1_k127_26878_3	56780.SYN_00824	7.326e-23	100.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2MRFT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
HKD1_k127_26878_1	1279009.ADICEAN_01121	2.858e-81	278.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
HKD1_k127_26878_2	156889.Mmc1_2423	6.006e-64	222.0	COG0110@1|root,COG0110@2|Bacteria,1RDCP@1224|Proteobacteria,2TWW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD1_k127_26878_0	1121104.AQXH01000001_gene1752	1.267e-134	435.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IR57@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_2694180_1	1492737.FEM08_00400	7.326e-139	445.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia,2NSVT@237|Flavobacterium	976|Bacteroidetes	S	nucleotide phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD1_k127_2694180_2	472759.Nhal_2106	1.203e-62	224.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales	135613|Chromatiales	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD1_k127_2694180_0	1107311.Q767_10395	2.945e-215	676.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia,2NTAJ@237|Flavobacterium	976|Bacteroidetes	J	metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HKD1_k127_2694180_3	1239962.C943_00093	1.563e-12	70.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,47KT5@768503|Cytophagia	976|Bacteroidetes	U	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
HKD1_k127_2714368_0	700598.Niako_6707	1.109e-251	786.0	COG1703@1|root,COG1884@1|root,COG2852@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2852@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD1_k127_2717094_0	700598.Niako_4693	5.645e-155	507.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IU7A@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_2742173_1	760192.Halhy_4109	1.018e-34	137.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1IUX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
HKD1_k127_2742173_2	1329250.WOSG25_051320	4.438e-16	86.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_2742173_0	1123277.KB893194_gene5847	2.353e-212	662.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,4NGSB@976|Bacteroidetes,47U8D@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
HKD1_k127_2794350_2	1123276.KB893313_gene3927	6.724e-41	157.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_2794350_3	179408.Osc7112_0484	3.807e-21	99.0	COG4319@1|root,COG4319@2|Bacteria,1G7EC@1117|Cyanobacteria,1HCEQ@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
HKD1_k127_2794350_1	485917.Phep_3297	1.328e-60	216.0	COG2141@1|root,COG2141@2|Bacteria,4NPX8@976|Bacteroidetes,1ISSB@117747|Sphingobacteriia	976|Bacteroidetes	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2794350_0	925409.KI911562_gene2243	4.894e-68	232.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IP1S@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_2815171_0	761193.Runsl_1970	1.839e-210	663.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_2815171_1	929556.Solca_0257	2.18e-65	229.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ8S@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_2819640_2	925409.KI911562_gene1069	5.396e-68	234.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes,1IXUP@117747|Sphingobacteriia	976|Bacteroidetes	L	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
HKD1_k127_2819640_1	700598.Niako_6205	6.066e-108	355.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1IX3A@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD1_k127_2819640_4	700598.Niako_6199	6.134e-44	162.0	COG0399@1|root,COG0399@2|Bacteria,4NS7A@976|Bacteroidetes	976|Bacteroidetes	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_2819640_3	700598.Niako_6206	2.003e-56	198.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1IYP8@117747|Sphingobacteriia	976|Bacteroidetes	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
HKD1_k127_2819640_0	700598.Niako_6207	6.809e-135	431.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1IVM8@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
HKD1_k127_28246_3	929713.NIASO_06320	2.899e-10	61.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1INTS@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
HKD1_k127_28246_0	700598.Niako_0366	1.225e-134	433.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1INX3@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD1_k127_28246_1	761193.Runsl_3172	5.131e-67	234.0	COG1280@1|root,COG1280@2|Bacteria,4NEG3@976|Bacteroidetes,47R5D@768503|Cytophagia	976|Bacteroidetes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD1_k127_28246_2	929713.NIASO_06305	1.462e-56	203.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD1_k127_282977_4	1267535.KB906767_gene4358	1.482e-24	116.0	COG2318@1|root,COG2318@2|Bacteria,3Y4TP@57723|Acidobacteria,2JJPR@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_282977_2	1123248.KB893326_gene1336	3.431e-150	479.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1IV4B@117747|Sphingobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD1_k127_282977_0	1122179.KB890426_gene3975	9.152e-197	627.0	COG4670@1|root,COG4670@2|Bacteria,4NIRA@976|Bacteroidetes	976|Bacteroidetes	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
HKD1_k127_282977_1	1239962.C943_01963	8.279e-178	574.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,47KS8@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD1_k127_282977_3	1123248.KB893328_gene937	8.091e-117	381.0	COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,1IQA4@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_282977_5	1536770.R50345_05105	4.003e-16	79.0	COG2084@1|root,COG2084@2|Bacteria,1VS8P@1239|Firmicutes,4HTTT@91061|Bacilli,26W6U@186822|Paenibacillaceae	91061|Bacilli	I	Dehydrogenase	yfjR	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
HKD1_k127_2859021_2	700598.Niako_2092	1.623e-118	385.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
HKD1_k127_2859021_0	700598.Niako_2093	4.803e-177	563.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD1_k127_2859021_3	1341181.FLJC2902T_24110	1.863e-14	74.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2NSBS@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HKD1_k127_2859021_1	742726.HMPREF9448_02019	2.4e-122	397.0	COG2207@1|root,COG2207@2|Bacteria,4NDYY@976|Bacteroidetes,2FNFA@200643|Bacteroidia,22WH9@171551|Porphyromonadaceae	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_2864045_0	1162668.LFE_1617	9.74e-49	184.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD1_k127_2864045_2	240292.Ava_1692	4.878e-15	79.0	COG0664@1|root,COG0664@2|Bacteria,1G54M@1117|Cyanobacteria,1HQQZ@1161|Nostocales	1117|Cyanobacteria	T	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_2864045_4	1313421.JHBV01000030_gene2044	9.303e-05	49.0	COG0664@1|root,COG0664@2|Bacteria,4NPU5@976|Bacteroidetes,1ITRP@117747|Sphingobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_2864045_1	1123037.AUDE01000060_gene2276	3.199e-15	82.0	2EY9N@1|root,33RI5@2|Bacteria,4P26G@976|Bacteroidetes,1I7K3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2864045_3	1443665.JACA01000005_gene251	3.583e-07	51.0	COG1396@1|root,COG1396@2|Bacteria,4PDQ4@976|Bacteroidetes,1IE4D@117743|Flavobacteriia,2YKRW@290174|Aquimarina	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_291089_3	700598.Niako_6623	3.061e-08	54.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_291089_0	700598.Niako_6625	2.498e-117	380.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_291089_1	1122605.KB893626_gene2743	1.821e-107	357.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_291089_2	700598.Niako_6627	4.908e-46	170.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1IU3P@117747|Sphingobacteriia	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
HKD1_k127_293844_2	700598.Niako_5815	1.267e-50	184.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HKD1_k127_293844_0	700598.Niako_5814	5.614e-109	362.0	COG0457@1|root,COG0457@2|Bacteria,4NME3@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
HKD1_k127_293844_1	1122605.KB893644_gene1512	3.698e-76	258.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1IRVU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HKD1_k127_294066_2	1267211.KI669560_gene1040	1.265e-51	183.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
HKD1_k127_294066_0	700598.Niako_5634	1.368e-107	353.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
HKD1_k127_294066_1	700598.Niako_5633	1.609e-106	357.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
HKD1_k127_2951024_3	700598.Niako_2311	5.415e-10	61.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IR4V@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
HKD1_k127_2951024_2	1122605.KB893643_gene909	8.19e-20	94.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1ITVJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD1_k127_2951024_0	700598.Niako_0910	5.776e-179	565.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD1_k127_2951024_1	700598.Niako_0909	4.919e-98	325.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD1_k127_2989251_2	1123248.KB893316_gene4578	6.029e-14	77.0	2ET5Y@1|root,33KQ0@2|Bacteria,4NZGA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2989251_0	1123248.KB893316_gene4577	1.375e-149	491.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IPFQ@117747|Sphingobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
HKD1_k127_2989251_1	700598.Niako_4412	3.003e-48	175.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
HKD1_k127_3000243_3	1122605.KB893632_gene4336	3.876e-177	565.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_3000243_1	700598.Niako_6993	2.118e-233	733.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1IQK8@117747|Sphingobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD1_k127_3000243_0	700598.Niako_6994	0.0	1307.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1IW9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
HKD1_k127_3000243_4	700598.Niako_6995	1.144e-156	503.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1J0KY@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3000243_7	1123248.KB893386_gene1963	1.269e-76	259.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,1IS13@117747|Sphingobacteriia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
HKD1_k127_3000243_9	929713.NIASO_11995	1.954e-65	226.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1ISB8@117747|Sphingobacteriia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HKD1_k127_3000243_8	700598.Niako_6998	3.637e-69	243.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1ITXE@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
HKD1_k127_3000243_6	700598.Niako_6999	1.222e-91	316.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_3000243_2	700598.Niako_7001	1.527e-186	588.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_3000243_5	929713.NIASO_17570	1.458e-149	482.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IP9S@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD1_k127_3021775_3	1453498.LG45_06855	8.904e-59	207.0	COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,1I3FC@117743|Flavobacteriia,2NWJX@237|Flavobacterium	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
HKD1_k127_3021775_6	1506583.JQJY01000005_gene2466	1.547e-36	142.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,1I3A8@117743|Flavobacteriia,2NWY8@237|Flavobacterium	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
HKD1_k127_3021775_7	491205.JARQ01000006_gene2694	2.32e-29	122.0	COG1672@1|root,COG1672@2|Bacteria,4PHWK@976|Bacteroidetes,1IN1D@117743|Flavobacteriia,3ZTRG@59732|Chryseobacterium	976|Bacteroidetes	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
HKD1_k127_3021775_5	1434325.AZQN01000001_gene573	1.402e-39	153.0	COG2318@1|root,COG2318@2|Bacteria,4NSP0@976|Bacteroidetes,47R5Z@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HKD1_k127_3021775_2	700598.Niako_2211	1.153e-61	220.0	COG0189@1|root,COG0189@2|Bacteria,4PN9C@976|Bacteroidetes	976|Bacteroidetes	HJ	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
HKD1_k127_3021775_1	700598.Niako_3841	1.135e-116	385.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,1IX9C@117747|Sphingobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
HKD1_k127_3021775_0	1116472.MGMO_17c00060	1.205e-203	658.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XEIK@135618|Methylococcales	135618|Methylococcales	KT	PFAM RNA polymerase sigma factor 54, interaction	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
HKD1_k127_3021775_4	700598.Niako_3551	5.114e-42	157.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1IW6M@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD1_k127_302586_2	1123248.KB893326_gene1346	7.666e-28	115.0	COG4828@1|root,COG4828@2|Bacteria,4NV5Z@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
HKD1_k127_302586_1	1536774.H70357_27205	7.355e-34	139.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD1_k127_302586_0	1185876.BN8_02801	2.951e-192	614.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,47U8K@768503|Cytophagia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
HKD1_k127_302586_3	485918.Cpin_2205	7.567e-18	91.0	COG0526@1|root,COG0526@2|Bacteria,4NRZT@976|Bacteroidetes,1IYF1@117747|Sphingobacteriia	976|Bacteroidetes	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HKD1_k127_304765_0	449447.MAE_01980	2.757e-112	370.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_304765_1	700598.Niako_6608	9.859e-73	248.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1ISDN@117747|Sphingobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
HKD1_k127_3049654_0	700598.Niako_4592	8.818e-102	333.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1IRAS@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD1_k127_3049654_2	1123248.KB893320_gene3892	5.658e-68	235.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISYU@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
HKD1_k127_3049654_1	1123248.KB893320_gene3893	2.903e-96	321.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
HKD1_k127_3049654_3	929562.Emtol_3082	1.244e-43	164.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
HKD1_k127_3062150_1	700598.Niako_4723	4.749e-28	125.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,TIG
HKD1_k127_3062150_0	1123248.KB893370_gene5046	1.184e-114	378.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1IWN2@117747|Sphingobacteriia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
HKD1_k127_3063932_5	1123248.KB893386_gene1934	9.055e-12	66.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,1J033@117747|Sphingobacteriia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
HKD1_k127_3063932_2	1123248.KB893386_gene1933	1.355e-139	451.0	COG2187@1|root,COG2187@2|Bacteria,4NKD3@976|Bacteroidetes,1IXH4@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
HKD1_k127_3063932_0	671143.DAMO_1138	0.0	1064.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdxB	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
HKD1_k127_3063932_4	700598.Niako_2283	1.618e-33	130.0	COG0236@1|root,COG0236@2|Bacteria,4NWTZ@976|Bacteroidetes,1IZ0C@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HKD1_k127_3063932_3	1123248.KB893386_gene1928	5.878e-108	359.0	COG0837@1|root,COG0837@2|Bacteria,4NGYX@976|Bacteroidetes,1IRRS@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
HKD1_k127_3063932_1	1123248.KB893326_gene1429	4.79e-160	512.0	COG0508@1|root,COG0508@2|Bacteria,4NE41@976|Bacteroidetes,1IVKR@117747|Sphingobacteriia	976|Bacteroidetes	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
HKD1_k127_3068125_4	1123248.KB893315_gene3167	6.515e-36	138.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD1_k127_3068125_6	700598.Niako_0889	1.87e-13	83.0	2EPP0@1|root,33H9M@2|Bacteria,4NXT6@976|Bacteroidetes,1IYX8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3068125_1	1123248.KB893315_gene3166	9.644e-115	381.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD1_k127_3068125_5	1107311.Q767_10125	1.13e-29	127.0	COG3637@1|root,COG3637@2|Bacteria,4NPV9@976|Bacteroidetes,1I47X@117743|Flavobacteriia,2NSX3@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD1_k127_3068125_2	929556.Solca_0290	5.836e-110	367.0	COG4775@1|root,COG4775@2|Bacteria,4NGTM@976|Bacteroidetes,1IW8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD1_k127_3068125_3	1121904.ARBP01000005_gene4823	3.671e-103	346.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
HKD1_k127_3068125_0	1122605.KB893628_gene4544	3.518e-259	808.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD1_k127_30742_2	700598.Niako_5072	2.017e-24	102.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_30742_0	1123248.KB893324_gene1673	2.247e-123	412.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_30742_1	700598.Niako_5077	3.333e-50	181.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
HKD1_k127_3075670_0	760192.Halhy_1525	3.321e-112	372.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1IS3N@117747|Sphingobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
HKD1_k127_3075670_1	1185876.BN8_06697	9.002e-73	258.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
HKD1_k127_3083108_1	700598.Niako_4725	8.727e-86	284.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD1_k127_3083108_3	1123248.KB893329_gene4470	5.326e-38	149.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
HKD1_k127_3083108_0	929713.NIASO_18465	9.833e-121	394.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HKD1_k127_3083108_2	929713.NIASO_09405	2.515e-49	180.0	COG2819@1|root,COG2819@2|Bacteria,4PMBF@976|Bacteroidetes,1J188@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_310353_0	700598.Niako_4395	3.282e-121	399.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1IP6M@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
HKD1_k127_310353_1	925409.KI911562_gene1543	2.099e-98	325.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD1_k127_3108345_0	1123248.KB893325_gene1222	1.509e-110	365.0	COG1082@1|root,COG1082@2|Bacteria,4NHM4@976|Bacteroidetes,1IV8U@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_3108345_3	1086011.HJ01_02860	3.504e-24	108.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia,2NWNA@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD1_k127_3108345_1	700598.Niako_5465	2.19e-34	138.0	295Z7@1|root,33C4F@2|Bacteria	2|Bacteria	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
HKD1_k127_3108345_4	929713.NIASO_14920	5.389e-23	100.0	2CT1X@1|root,32SSE@2|Bacteria,4NU3X@976|Bacteroidetes,1ITPW@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3108345_2	1123248.KB893316_gene4665	1.645e-30	123.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD1_k127_3118442_1	700598.Niako_6603	2.39e-78	269.0	COG2133@1|root,COG2133@2|Bacteria,4NIMV@976|Bacteroidetes,1ISA9@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD1_k127_3118442_0	925409.KI911562_gene908	4.911e-110	361.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1IQF9@117747|Sphingobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
HKD1_k127_3118442_2	761193.Runsl_3835	2.373e-67	234.0	COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,47QTJ@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_3118442_5	1121904.ARBP01000001_gene5953	6.099e-36	139.0	COG3631@1|root,COG3631@2|Bacteria,4NVNP@976|Bacteroidetes,47SCI@768503|Cytophagia	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD1_k127_3118442_3	700598.Niako_4622	7.204e-51	184.0	COG2259@1|root,COG2259@2|Bacteria,4NPF6@976|Bacteroidetes,1ISCU@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
HKD1_k127_3118442_4	700598.Niako_6600	2.607e-36	138.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD1_k127_3118442_6	700598.Niako_6599	3.683e-20	94.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD1_k127_31319_5	376686.Fjoh_4632	1.71e-05	48.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,1HZZA@117743|Flavobacteriia,2NTWR@237|Flavobacterium	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_31319_1	608538.HTH_0154	2.071e-76	266.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
HKD1_k127_31319_0	608538.HTH_0153	5.194e-258	805.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HKD1_k127_31319_2	608538.HTH_0151	1.824e-46	177.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD1_k127_31319_4	608538.HTH_0156	5.356e-11	66.0	COG1148@1|root,COG1290@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	napF	-	-	ko:K02572,ko:K02573,ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	CCG,Cytochrome_B,FAD_binding_6,Fer2,Fer4,Fer4_4,Fer4_5,Fer4_7,FlpD,NAD_binding_1
HKD1_k127_3136651_0	925409.KI911562_gene2963	1.496e-159	509.0	COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1IRDC@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3136651_1	1122605.KB893637_gene3064	5.1e-121	394.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1IPYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	GMP synthase-glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
HKD1_k127_3136651_2	1121930.AQXG01000004_gene2850	1.261e-11	65.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD1_k127_3138762_4	700598.Niako_6842	1.902e-42	158.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1INX6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD1_k127_3138762_0	1122605.KB893637_gene3290	5.568e-138	464.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane cobalamin receptor protein	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
HKD1_k127_3138762_3	929713.NIASO_08330	1.64e-71	248.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
HKD1_k127_3138762_1	1123248.KB893386_gene1857	2.646e-93	316.0	COG3734@1|root,COG3734@2|Bacteria,4NIGZ@976|Bacteroidetes,1IWBG@117747|Sphingobacteriia	976|Bacteroidetes	G	2-keto-3-deoxy-galactonokinase	-	-	2.7.1.58	ko:K00883	ko00052,ko01100,map00052,map01100	M00552	R03387	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DGOK
HKD1_k127_3138762_2	1492737.FEM08_07500	9.382e-82	282.0	COG0628@1|root,COG0628@2|Bacteria,4NN3B@976|Bacteroidetes,1HYEH@117743|Flavobacteriia,2NUR6@237|Flavobacterium	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_3149746_6	700598.Niako_3142	2.053e-149	479.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IWUF@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD1_k127_3149746_5	1123278.KB893563_gene4535	8.615e-168	533.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47M5M@768503|Cytophagia	976|Bacteroidetes	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD1_k127_3149746_0	929713.NIASO_01825	5e-324	1005.0	COG3661@1|root,COG3661@2|Bacteria,4NHE2@976|Bacteroidetes,1IPVK@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
HKD1_k127_3149746_7	700598.Niako_0750	1.523e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,4NIH6@976|Bacteroidetes,1IQMX@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
HKD1_k127_3149746_4	700598.Niako_2443	3.026e-170	542.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,1IQRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
HKD1_k127_3149746_2	1392490.JHZX01000001_gene747	7.518e-242	754.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia	976|Bacteroidetes	G	COG2211 Na melibiose symporter and related	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HKD1_k127_3149746_3	929713.NIASO_01840	1.297e-178	564.0	COG3507@1|root,COG3507@2|Bacteria,4NEWE@976|Bacteroidetes,1IQBX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynB	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
HKD1_k127_3149746_1	760192.Halhy_3927	4.203e-261	811.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
HKD1_k127_3155128_1	1123248.KB893316_gene4689	2.986e-116	377.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1IRRN@117747|Sphingobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HKD1_k127_3155128_0	760192.Halhy_5008	1.853e-191	610.0	COG1680@1|root,COG3394@1|root,COG1680@2|Bacteria,COG3394@2|Bacteria,4NEVS@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,YdjC
HKD1_k127_3165585_0	1123277.KB893172_gene840	0.0	1135.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NH06@976|Bacteroidetes,47MID@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_3165585_3	504472.Slin_1768	3.334e-178	574.0	28K2T@1|root,33QGE@2|Bacteria,4P0RB@976|Bacteroidetes,47XJ0@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
HKD1_k127_3165585_1	700598.Niako_5795	5.685e-274	850.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
HKD1_k127_3165585_13	714943.Mucpa_2551	5.367e-06	48.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3165585_7	1122605.KB893646_gene90	2.821e-82	282.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HKD1_k127_3165585_10	1122605.KB893646_gene91	4.282e-57	199.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1ISXQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD1_k127_3165585_5	700598.Niako_5791	5.134e-128	418.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
HKD1_k127_3165585_9	700598.Niako_5789	3.673e-68	233.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD1_k127_3165585_4	925409.KI911562_gene1104	1.839e-149	486.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IVGY@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HKD1_k127_3165585_8	1123248.KB893348_gene82	2.753e-78	267.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3165585_6	700598.Niako_5786	5.405e-91	303.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
HKD1_k127_3165585_2	700598.Niako_5785	1.857e-232	726.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	Fer4_8,LUD_dom
HKD1_k127_3165585_11	700598.Niako_5784	8.983e-32	128.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_316609_3	880072.Desac_1716	5.184e-14	76.0	2ER3W@1|root,33IPG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_316609_1	1123248.KB893359_gene2211	6.359e-20	96.0	2E2RH@1|root,32XTZ@2|Bacteria,4NTV2@976|Bacteroidetes,1IZZE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_316609_0	671143.DAMO_0892	9.399e-114	377.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.38	ko:K01371	ko04142,ko04210,ko04380,ko04620,ko05323,map04142,map04210,map04380,map04620,map05323	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_C1
HKD1_k127_316609_2	1301098.PKB_2924	3.497e-14	80.0	COG1876@1|root,COG1876@2|Bacteria,1PHKT@1224|Proteobacteria,1SS6H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
HKD1_k127_316609_4	231434.JQJH01000006_gene139	2.255e-08	59.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3NC6I@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_3175788_0	509635.N824_25370	1.921e-250	778.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,1IR0K@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
HKD1_k127_3175788_1	509635.N824_25355	4.329e-21	96.0	COG1047@1|root,COG1047@2|Bacteria	2|Bacteria	O	modulation by symbiont of host adenylate cyclase-mediated signal transduction	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
HKD1_k127_318621_0	700598.Niako_6800	0.0	1140.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1IP8M@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD1_k127_318621_1	468059.AUHA01000002_gene563	3.226e-77	272.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_3200549_1	700598.Niako_0413	9.784e-72	247.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_3200549_3	657309.BXY_35690	3.713e-18	98.0	COG0810@1|root,COG0810@2|Bacteria,4NSYT@976|Bacteroidetes,2FP10@200643|Bacteroidia,4AMQ3@815|Bacteroidaceae	976|Bacteroidetes	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
HKD1_k127_3200549_0	700598.Niako_0411	8.173e-98	326.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,1IPA5@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD1_k127_3200549_2	1122605.KB893627_gene2928	4.434e-65	231.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD1_k127_3200971_1	1123248.KB893320_gene3912	4.411e-204	640.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1IVKJ@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
HKD1_k127_3200971_0	760192.Halhy_2702	1.421e-302	935.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,1IWMS@117747|Sphingobacteriia	976|Bacteroidetes	GP	Arylesterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
HKD1_k127_3200971_4	946077.W5A_06446	6.802e-87	301.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3200971_3	468059.AUHA01000007_gene2663	2.358e-101	338.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_3200971_2	468059.AUHA01000007_gene2662	2.399e-111	372.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1IVIT@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_3200971_5	468059.AUHA01000007_gene2661	3.372e-23	100.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_3203319_3	118161.KB235922_gene353	1.082e-30	132.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HKD1_k127_3203319_0	1300143.CCAV010000001_gene1193	7.538e-116	381.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia,3ZNHA@59732|Chryseobacterium	976|Bacteroidetes	G	Inward rectifier potassium channel Irk	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
HKD1_k127_3203319_1	700598.Niako_2168	3.568e-115	375.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD1_k127_3203319_2	1123248.KB893323_gene1574	4.989e-65	224.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HKD1_k127_3221367_1	1123278.KB893411_gene2848	2.815e-116	381.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,47N3H@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_3221367_0	1123248.KB893359_gene2060	2.281e-121	402.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1IQHN@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
HKD1_k127_3221367_2	925409.KI911562_gene1822	4.636e-114	372.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes,1IXF2@117747|Sphingobacteriia	976|Bacteroidetes	F	Thymidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD1_k127_3221367_3	1168289.AJKI01000040_gene3227	2.419e-05	46.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,2FSKM@200643|Bacteroidia,3XK9R@558415|Marinilabiliaceae	976|Bacteroidetes	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
HKD1_k127_3225190_2	929713.NIASO_02175	1.375e-81	276.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD1_k127_3225190_0	1267211.KI669560_gene1400	8.708e-224	699.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD1_k127_3225190_3	203275.BFO_2640	1.028e-49	190.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
HKD1_k127_3225190_1	700598.Niako_0331	4.383e-84	287.0	COG0448@1|root,COG0448@2|Bacteria,4PKFG@976|Bacteroidetes,1IPMM@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
HKD1_k127_3231924_3	204669.Acid345_1385	3.72e-119	385.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
HKD1_k127_3231924_8	1210884.HG799466_gene12574	1.158e-38	151.0	2EDAV@1|root,33776@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3231924_5	1123248.KB893386_gene1879	4.656e-108	360.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
HKD1_k127_3231924_6	925409.KI911562_gene745	1.194e-76	267.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1IXDH@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_3231924_7	700598.Niako_6092	1.855e-61	215.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1ITFC@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
HKD1_k127_3231924_0	700598.Niako_6094	1.432e-312	965.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
HKD1_k127_3231924_4	929556.Solca_3570	1.299e-116	383.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1IRAE@117747|Sphingobacteriia	976|Bacteroidetes	GM	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_3231924_2	468059.AUHA01000002_gene41	6.018e-147	471.0	COG1216@1|root,COG1216@2|Bacteria,4NGEQ@976|Bacteroidetes,1IPXG@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_3231924_1	1123248.KB893322_gene570	1.822e-161	520.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
HKD1_k127_3235286_11	1123037.AUDE01000060_gene2276	1.005e-15	82.0	2EY9N@1|root,33RI5@2|Bacteria,4P26G@976|Bacteroidetes,1I7K3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3235286_1	1123248.KB893323_gene1633	2.259e-312	978.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,4NG9Q@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
HKD1_k127_3235286_9	929713.NIASO_07555	3.279e-65	229.0	COG3946@1|root,COG3946@2|Bacteria,4NTTD@976|Bacteroidetes,1IXZ2@117747|Sphingobacteriia	976|Bacteroidetes	U	Bacterial virulence protein (VirJ)	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
HKD1_k127_3235286_10	700598.Niako_6011	3.944e-59	209.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1ISQR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
HKD1_k127_3235286_3	700598.Niako_7289	1.161e-168	532.0	KOG1573@1|root,2Z822@2|Bacteria,4NFQF@976|Bacteroidetes,1IPN5@117747|Sphingobacteriia	976|Bacteroidetes	S	Inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
HKD1_k127_3235286_2	700598.Niako_7287	8.78e-300	925.0	COG0591@1|root,COG0591@2|Bacteria,4P03M@976|Bacteroidetes,1IW9I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD1_k127_3235286_6	1122605.KB893647_gene340	7.528e-109	355.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
HKD1_k127_3235286_0	1123248.KB893322_gene617	5.44e-321	1013.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD1_k127_3235286_4	700598.Niako_6016	9.765e-139	455.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
HKD1_k127_3235286_7	1123248.KB893348_gene187	2.45e-102	336.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
HKD1_k127_3235286_5	700598.Niako_6018	4.17e-135	435.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
HKD1_k127_3248783_0	700598.Niako_6800	1.088e-203	643.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1IP8M@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD1_k127_3275046_4	1185876.BN8_02715	2.936e-54	195.0	COG0454@1|root,COG0456@2|Bacteria,4NU6N@976|Bacteroidetes,47VGZ@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_3275046_0	929713.NIASO_08895	2.676e-209	655.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_3275046_1	1123248.KB893314_gene3282	5.267e-150	482.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IPZG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD1_k127_3275046_2	700598.Niako_4383	7.317e-115	375.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1INQT@117747|Sphingobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
HKD1_k127_3275046_3	1122605.KB893627_gene2868	1.182e-63	225.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1ISFV@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
HKD1_k127_3275046_5	929713.NIASO_07710	0.0001416	44.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HKD1_k127_3282771_2	1122605.KB893637_gene3068	1.025e-98	327.0	COG0861@1|root,COG0861@2|Bacteria,4NH6F@976|Bacteroidetes,1J0BP@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
HKD1_k127_3282771_0	700598.Niako_5587	2.749e-146	472.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD1_k127_3282771_1	700598.Niako_5586	4.518e-131	421.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD1_k127_3284813_3	1267211.KI669560_gene2790	2.229e-46	169.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_3284813_0	700598.Niako_6932	2.315e-113	372.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1IS3D@117747|Sphingobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
HKD1_k127_3284813_1	929713.NIASO_14145	2.551e-95	322.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD1_k127_3284813_2	700598.Niako_6930	3.363e-72	248.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HKD1_k127_3290706_6	485918.Cpin_1616	3.036e-88	293.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1IRTU@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HKD1_k127_3290706_5	929713.NIASO_08545	4.699e-106	346.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HKD1_k127_3290706_9	700598.Niako_4684	2.034e-55	196.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1ISQN@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HKD1_k127_3290706_0	700598.Niako_3686	0.0	1287.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD1_k127_3290706_10	1122605.KB893647_gene491	7.716e-52	189.0	COG3637@1|root,COG3637@2|Bacteria,4NWNN@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
HKD1_k127_3290706_1	929713.NIASO_12095	9.249e-164	525.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1IPSC@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA mismatch repair protein MutT	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HKD1_k127_3290706_4	925409.KI911562_gene2946	1.566e-107	353.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
HKD1_k127_3290706_2	1122605.KB893647_gene493	6.007e-144	459.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD1_k127_3290706_12	1168034.FH5T_02850	6.624e-30	122.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,2G3HH@200643|Bacteroidia	976|Bacteroidetes	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_3290706_3	1123248.KB893337_gene2341	3.132e-135	437.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1IPCV@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD1_k127_3290706_11	1122605.KB893647_gene495	3.275e-46	174.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1ITDS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3290706_7	925409.KI911562_gene2950	7.329e-82	276.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD1_k127_3330841_0	236814.IX39_00680	3.843e-67	234.0	COG0664@1|root,COG0664@2|Bacteria,4NEUF@976|Bacteroidetes,1IFWU@117743|Flavobacteriia,3ZRGG@59732|Chryseobacterium	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_3330841_3	1123248.KB893370_gene5147	2.659e-17	88.0	COG3631@1|root,COG3631@2|Bacteria,4NZ7M@976|Bacteroidetes,1IZKD@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD1_k127_3330841_2	153721.MYP_3109	3.035e-59	207.0	COG4898@1|root,COG4898@2|Bacteria,4NQGY@976|Bacteroidetes,47RED@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD1_k127_3330841_1	925409.KI911562_gene2041	4.124e-67	237.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1IR2J@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_333477_3	929703.KE386491_gene1337	2.415e-30	121.0	COG3558@1|root,COG3558@2|Bacteria,4NP0B@976|Bacteroidetes,47PRY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
HKD1_k127_333477_1	991.IW20_15190	5.705e-75	258.0	COG2128@1|root,COG2128@2|Bacteria,4NI74@976|Bacteroidetes,1I27V@117743|Flavobacteriia,2NZY1@237|Flavobacterium	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD1_k127_333477_0	700598.Niako_0644	9.672e-92	307.0	COG3279@1|root,COG3279@2|Bacteria,4NHUZ@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_333477_2	700598.Niako_0643	5.031e-61	216.0	COG2972@1|root,COG2972@2|Bacteria,4NIRC@976|Bacteroidetes,1J05H@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD1_k127_3362357_2	272844.PAB0789	7.572e-78	269.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,243PG@183968|Thermococci	183968|Thermococci	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD1_k127_3362357_0	1220534.B655_0882	1.52e-134	435.0	COG0451@1|root,arCOG01376@2157|Archaea,2XVGW@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD1_k127_3362357_4	1499683.CCFF01000017_gene2832	6.265e-57	206.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,36DWD@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
HKD1_k127_3362357_1	700598.Niako_7268	8.728e-128	419.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
HKD1_k127_3362357_3	700598.Niako_5554	3.629e-62	223.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	wbxA	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_3375693_0	1123248.KB893359_gene2016	1.698e-173	550.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IWIH@117747|Sphingobacteriia	976|Bacteroidetes	O	FtsH Extracellular	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD1_k127_3375693_2	1286171.EAL2_c15250	3.295e-23	104.0	COG1371@1|root,COG1371@2|Bacteria,1VX66@1239|Firmicutes,252E3@186801|Clostridia	186801|Clostridia	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
HKD1_k127_3375693_1	1121875.KB907549_gene1741	5.768e-159	510.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,1HYNX@117743|Flavobacteriia	976|Bacteroidetes	S	RNA 2',3'-cyclic phosphate--5'-hydroxyl ligase	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
HKD1_k127_3383006_0	1122605.KB893648_gene3661	6.308e-209	656.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HKD1_k127_3383006_1	925409.KI911562_gene1543	4.326e-59	209.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD1_k127_3413318_2	700598.Niako_1623	2.981e-117	385.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
HKD1_k127_3413318_3	1492738.FEM21_05750	1.938e-47	175.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia,2NW1K@237|Flavobacterium	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_3413318_0	700598.Niako_1514	2.389e-183	589.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1IV25@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_3413318_1	700598.Niako_1515	7.984e-148	483.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
HKD1_k127_341343_0	700598.Niako_5028	1.896e-146	474.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD1_k127_341343_1	700598.Niako_5029	1.158e-142	464.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
HKD1_k127_341343_3	742725.HMPREF9450_02296	0.0006898	49.0	2EKSY@1|root,33EGP@2|Bacteria,4NXJC@976|Bacteroidetes,2FVKV@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG23390 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_341343_2	1267211.KI669560_gene2365	1.083e-28	115.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1IS2H@117747|Sphingobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD1_k127_3420240_1	1185876.BN8_06334	1.281e-144	470.0	COG0531@1|root,COG0531@2|Bacteria,4NIB8@976|Bacteroidetes,47MKD@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD1_k127_3420240_2	761193.Runsl_4834	1.036e-93	312.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,47NGU@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD1_k127_3420240_0	700598.Niako_4955	8.832e-150	479.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD1_k127_3430256_1	929703.KE386491_gene1336	5.375e-97	321.0	COG2207@1|root,COG2207@2|Bacteria,4NHSP@976|Bacteroidetes,47QVJ@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_3430256_2	1123248.KB893326_gene1277	3.777e-54	195.0	COG0431@1|root,COG0431@2|Bacteria,4NQ3Y@976|Bacteroidetes,1ISVG@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_3430256_3	1484460.JSWG01000007_gene3124	5.018e-34	137.0	COG1247@1|root,COG1247@2|Bacteria,4PKRB@976|Bacteroidetes,1IJDC@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_3430256_0	1286632.P278_00800	2.071e-201	637.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
HKD1_k127_34313_4	1123248.KB893316_gene4578	1.923e-17	90.0	2ET5Y@1|root,33KQ0@2|Bacteria,4NZGA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_34313_1	925409.KI911562_gene2260	2.98e-104	346.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD1_k127_34313_2	1122605.KB893625_gene2049	6.36e-88	298.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
HKD1_k127_34313_3	1227739.Hsw_3789	8.362e-80	282.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD1_k127_34313_0	1122605.KB893637_gene3200	3.092e-126	405.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
HKD1_k127_3440621_2	925409.KI911562_gene346	3.195e-66	231.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD1_k127_3440621_0	1379270.AUXF01000007_gene997	2.702e-91	312.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_3440621_1	221288.JH992901_gene5748	8.38e-68	264.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
HKD1_k127_3470151_0	1267211.KI669560_gene2596	3.004e-292	910.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD1_k127_3470151_4	1123248.KB893314_gene3473	2.661e-50	183.0	COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,1IST7@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD1_k127_3470151_3	1122605.KB893627_gene3022	6.398e-86	292.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1IRXQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
HKD1_k127_3470151_5	379066.GAU_3070	8.014e-40	151.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
HKD1_k127_3470151_6	760192.Halhy_5072	9.337e-10	66.0	2EMRS@1|root,33FE8@2|Bacteria,4NXJD@976|Bacteroidetes	976|Bacteroidetes	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
HKD1_k127_3470151_2	700598.Niako_5527	4.742e-96	322.0	COG0382@1|root,COG0382@2|Bacteria,4NK26@976|Bacteroidetes,1IS1A@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD1_k127_3470151_1	700598.Niako_5528	2.254e-110	363.0	COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,1IRE8@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
HKD1_k127_3478302_3	1123248.KB893385_gene4843	1.851e-70	247.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD1_k127_3478302_0	1122605.KB893644_gene1229	2.992e-158	508.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
HKD1_k127_3478302_1	700598.Niako_1564	2.584e-125	413.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
HKD1_k127_3478302_2	1122605.KB893644_gene1228	2.296e-119	386.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD1_k127_3515516_1	1123248.KB893348_gene281	3.776e-112	370.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD1_k127_3515516_2	700598.Niako_6547	1.058e-97	322.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1IY3D@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
HKD1_k127_3515516_0	700598.Niako_6636	2.916e-121	390.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1IPG1@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD1_k127_351783_2	1550091.JROE01000013_gene127	9.816e-54	199.0	2EMPU@1|root,33FC9@2|Bacteria,4NZ8E@976|Bacteroidetes,1IZRJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_351783_1	1434325.AZQN01000004_gene1792	1.018e-179	579.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,47M7F@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
HKD1_k127_351783_0	1550091.JROE01000013_gene125	1.715e-276	871.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1J0U5@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_3563414_4	925409.KI911562_gene2162	3.407e-36	138.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD1_k127_3563414_6	1380384.JADN01000004_gene2219	4.984e-05	51.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia	976|Bacteroidetes	D	peptidase M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_3563414_5	929556.Solca_1429	3.401e-27	113.0	COG2207@1|root,COG2207@2|Bacteria,4NVDF@976|Bacteroidetes,1IU6I@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3563414_1	929556.Solca_1447	3.578e-69	247.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1IPKR@117747|Sphingobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
HKD1_k127_3563414_3	1406840.Q763_10205	2.382e-41	158.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1I3AB@117743|Flavobacteriia,2P02M@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_3563414_2	1123248.KB893318_gene4143	5.162e-67	235.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1IXTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
HKD1_k127_3563414_0	929713.NIASO_11295	0.0	1047.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD1_k127_3578628_1	700598.Niako_6959	1.917e-138	442.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
HKD1_k127_3578628_0	700598.Niako_5728	2.67e-152	486.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_3578628_2	485918.Cpin_7185	1.789e-07	52.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1ITKI@117747|Sphingobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
HKD1_k127_3581575_0	929713.NIASO_14290	3.339e-275	851.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
HKD1_k127_3581575_2	929713.NIASO_14295	5.293e-151	485.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1IPEE@117747|Sphingobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
HKD1_k127_3581575_1	1122605.KB893626_gene2520	3.467e-171	546.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1IPBN@117747|Sphingobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3581575_3	925409.KI911562_gene1019	1.073e-69	240.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD1_k127_35872_5	700598.Niako_5740	1.187e-32	130.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD1_k127_35872_2	700598.Niako_5741	1.168e-267	844.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1IVTD@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
HKD1_k127_35872_3	700598.Niako_5742	1.059e-109	359.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD1_k127_35872_0	700598.Niako_2199	5.248e-307	947.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1IR41@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HKD1_k127_35872_8	1121011.AUCB01000009_gene1963	5.598e-05	54.0	2DTB4@1|root,32UUV@2|Bacteria,4NSRC@976|Bacteroidetes,1I40G@117743|Flavobacteriia,23HD6@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_35872_4	236814.IX39_04855	1.444e-97	324.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia,3ZNI2@59732|Chryseobacterium	976|Bacteroidetes	F	Purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_35872_1	700598.Niako_2200	1.829e-268	833.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HKD1_k127_35872_7	1267211.KI669560_gene1865	1.392e-08	55.0	COG1961@1|root,COG1961@2|Bacteria,4NHXM@976|Bacteroidetes	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_35872_6	925409.KI911562_gene2486	3.245e-21	94.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1IQ5P@117747|Sphingobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD1_k127_359193_4	643867.Ftrac_1357	6.24e-09	64.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,47TZD@768503|Cytophagia	976|Bacteroidetes	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_359193_1	700598.Niako_6926	8.021e-109	359.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1IR07@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD1_k127_359193_0	700598.Niako_6927	1.281e-129	420.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1IQNE@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD1_k127_359193_3	700598.Niako_1283	3.182e-17	89.0	2E82X@1|root,34BW2@2|Bacteria,4P6AY@976|Bacteroidetes,1IZ0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_359193_2	925409.KI911562_gene1209	6.666e-64	225.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1IS01@117747|Sphingobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD1_k127_364889_2	700598.Niako_5130	1.162e-59	209.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_364889_3	880073.Calab_0150	2.118e-31	134.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HKD1_k127_364889_1	743722.Sph21_2661	3.14e-84	284.0	COG4122@1|root,COG4122@2|Bacteria,4PBU0@976|Bacteroidetes,1IZHJ@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
HKD1_k127_364889_0	1454007.JAUG01000083_gene2258	2.381e-207	653.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1IPHU@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD1_k127_3660_3	929713.NIASO_20375	3.59e-43	158.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD1_k127_3660_4	1122605.KB893645_gene1172	2.059e-36	140.0	COG0261@1|root,COG0261@2|Bacteria	2|Bacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HKD1_k127_3660_0	700598.Niako_0577	3.675e-266	825.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IP9C@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD1_k127_3660_1	925409.KI911562_gene2590	2.249e-204	641.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,1IPQJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
HKD1_k127_3660_2	925409.KI911562_gene2589	1.063e-179	572.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HKD1_k127_3660_5	1123248.KB893320_gene3894	1.298e-17	91.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_3696990_0	1150600.ADIARSV_3427	5.132e-68	236.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1IRNM@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD1_k127_3696990_2	700598.Niako_1661	1.285e-48	177.0	COG2259@1|root,33816@2|Bacteria,4NUVH@976|Bacteroidetes	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
HKD1_k127_3696990_3	700598.Niako_5911	1.672e-17	83.0	COG0500@1|root,COG0500@2|Bacteria,4NZ1V@976|Bacteroidetes	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3696990_4	925409.KI911562_gene966	4.706e-06	51.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,1IPXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt,AHSA1
HKD1_k127_3696990_1	762903.Pedsa_1858	4.574e-51	184.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
HKD1_k127_3702042_1	700598.Niako_4435	5.273e-113	369.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD1_k127_3702042_4	929713.NIASO_08580	2.165e-59	208.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1ISBS@117747|Sphingobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD1_k127_3702042_3	925409.KI911562_gene1866	2.755e-84	283.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1IRF3@117747|Sphingobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD1_k127_3702042_0	485918.Cpin_1911	3.929e-161	514.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1IP51@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_3702042_2	700598.Niako_4430	5.394e-105	346.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
HKD1_k127_371007_7	743722.Sph21_4659	8.446e-72	253.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IR93@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_371007_8	925409.KI911562_gene882	3.046e-68	242.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1IS0E@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
HKD1_k127_371007_10	1123248.KB893319_gene4073	2.452e-52	188.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD1_k127_371007_1	700598.Niako_5766	1.541e-320	993.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HKD1_k127_371007_5	1122605.KB893646_gene139	1.668e-83	281.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
HKD1_k127_371007_11	1122605.KB893646_gene140	9.233e-43	160.0	COG2105@1|root,COG2105@2|Bacteria,4NUSS@976|Bacteroidetes,1IZG0@117747|Sphingobacteriia	976|Bacteroidetes	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
HKD1_k127_371007_3	1122605.KB893646_gene142	6.12e-134	430.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
HKD1_k127_371007_6	700598.Niako_5762	7.024e-72	251.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_371007_4	700598.Niako_5761	4.33e-110	366.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1INNS@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
HKD1_k127_371007_9	700598.Niako_5758	3.57e-55	199.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1ISX9@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD1_k127_371007_2	700598.Niako_5729	7.497e-137	442.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_371007_0	929713.NIASO_14720	0.0	1249.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD1_k127_3714999_1	1123248.KB893314_gene3634	8.8e-59	206.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
HKD1_k127_3714999_2	700598.Niako_5625	5.569e-34	134.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IZ3M@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_3714999_0	929713.NIASO_16800	1.858e-87	294.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD1_k127_372368_2	485917.Phep_3884	2.941e-67	231.0	COG3347@1|root,COG4221@1|root,COG3347@2|Bacteria,COG4221@2|Bacteria,4NEM0@976|Bacteroidetes,1IQ2J@117747|Sphingobacteriia	976|Bacteroidetes	IQ	rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
HKD1_k127_372368_0	1123248.KB893359_gene2079	1.669e-198	621.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
HKD1_k127_372368_1	929562.Emtol_3173	3.436e-104	346.0	COG0657@1|root,COG0657@2|Bacteria,4PKKH@976|Bacteroidetes,47KC9@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
HKD1_k127_3724398_1	985255.APHJ01000039_gene248	6.536e-78	268.0	COG1228@1|root,COG1228@2|Bacteria,4NGJV@976|Bacteroidetes,1I000@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD1_k127_3724398_2	985255.APHJ01000039_gene248	9.885e-69	239.0	COG1228@1|root,COG1228@2|Bacteria,4NGJV@976|Bacteroidetes,1I000@117743|Flavobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD1_k127_3724398_4	1492737.FEM08_21720	2.679e-25	115.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3724398_3	1492737.FEM08_21720	4.757e-34	141.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3724398_5	1492737.FEM08_21720	6.05e-13	78.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3724398_0	1121889.AUDM01000024_gene1276	7.835e-89	301.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD1_k127_3724604_2	1089547.KB913013_gene369	5.339e-80	275.0	COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47NAC@768503|Cytophagia	976|Bacteroidetes	E	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD1_k127_3724604_0	925409.KI911562_gene1367	6.004e-257	796.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1IP02@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
HKD1_k127_3724604_1	1191523.MROS_0031	2.984e-84	282.0	COG4146@1|root,COG4146@2|Bacteria	2|Bacteria	S	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD1_k127_372928_2	929713.NIASO_13035	7.673e-48	173.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,1IP8J@117747|Sphingobacteriia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD1_k127_372928_0	929713.NIASO_13030	9.374e-211	667.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP88@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD1_k127_372928_1	700598.Niako_6870	4.671e-149	477.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD1_k127_373492_4	700598.Niako_5550	2.05e-68	233.0	COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,1IPHP@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
HKD1_k127_373492_1	1123248.KB893334_gene2751	2.11e-194	619.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
HKD1_k127_373492_2	700598.Niako_5551	4.156e-166	537.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1IRN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase M1 membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
HKD1_k127_373492_0	929713.NIASO_19690	1.453e-277	859.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HKD1_k127_373492_6	926549.KI421517_gene1149	2.213e-29	124.0	297E6@1|root,2ZUMN@2|Bacteria,4NPTI@976|Bacteroidetes,47R84@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_373492_3	1183438.GKIL_4228	1.769e-69	247.0	COG2227@1|root,COG2227@2|Bacteria,1GAKA@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD1_k127_373492_5	1355368.JART01000023_gene1456	6.487e-55	204.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2YNN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
HKD1_k127_373492_7	1450525.JATV01000006_gene941	9.366e-07	51.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1HZ9Z@117743|Flavobacteriia,2NVB6@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_3790091_2	1123248.KB893314_gene3555	1.752e-09	59.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3790091_3	1209984.BN978_02866	2.423e-08	58.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria,23A7Y@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
HKD1_k127_3790091_1	1122605.KB893634_gene4209	4.776e-65	229.0	COG1216@1|root,COG1216@2|Bacteria,4NETR@976|Bacteroidetes,1J11G@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_3790091_0	1313421.JHBV01000003_gene611	3.693e-129	425.0	COG0463@1|root,COG0463@2|Bacteria,4PM7S@976|Bacteroidetes	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_3826858_0	929556.Solca_3531	2.187e-256	808.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1IQ1D@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
HKD1_k127_3826858_5	925409.KI911562_gene2625	9.513e-164	520.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IWBC@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD1_k127_3826858_4	468059.AUHA01000006_gene2903	6.684e-196	625.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD1_k127_3826858_2	929713.NIASO_08770	1.73e-234	732.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1IQCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD1_k127_3826858_3	929713.NIASO_08765	1.66e-215	675.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD1_k127_3826858_1	1454007.JAUG01000086_gene4021	7.865e-242	752.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
HKD1_k127_3826858_6	1166018.FAES_3356	4.677e-75	258.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MXA@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
HKD1_k127_3849594_0	760192.Halhy_4898	1.778e-251	782.0	COG3250@1|root,COG3867@1|root,COG3250@2|Bacteria,COG3867@2|Bacteria,4NEWN@976|Bacteroidetes,1IRAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HKD1_k127_3849594_1	1123248.KB893314_gene3717	1.51e-55	198.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes,1ITYU@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM Peptidase S24 S26A S26B, conserved region	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
HKD1_k127_3855135_5	1123248.KB893314_gene3593	3.499e-29	117.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD1_k127_3855135_4	313606.M23134_05196	5.868e-42	157.0	2B1XW@1|root,31UE7@2|Bacteria,4NY8Q@976|Bacteroidetes,47W4P@768503|Cytophagia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_3855135_2	700598.Niako_0894	5.063e-140	447.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
HKD1_k127_3855135_1	504472.Slin_4734	4.821e-281	880.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
HKD1_k127_3855135_0	1122605.KB893629_gene4130	0.0	1298.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3855135_3	700598.Niako_1212	4.404e-80	268.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD1_k127_3862913_5	1202532.FF52_15677	1.402e-08	57.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,1I6B8@117743|Flavobacteriia,2NW45@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3862913_1	700598.Niako_2485	1.521e-82	282.0	2DWQN@1|root,341FB@2|Bacteria,4P4AQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
HKD1_k127_3862913_2	926559.JoomaDRAFT_2112	3.241e-41	160.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HKD1_k127_3862913_4	926559.JoomaDRAFT_2115	1.263e-14	83.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,1I1GT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3862913_0	1123248.KB893329_gene4495	1.485e-136	440.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1IW51@117747|Sphingobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD1_k127_3862913_3	1250232.JQNJ01000001_gene3282	6.408e-28	114.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I37G@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
HKD1_k127_3908_3	1123248.KB893315_gene3175	2.192e-46	168.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD1_k127_3908_4	1506583.JQJY01000002_gene1452	1.435e-12	77.0	2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,1I5GH@117743|Flavobacteriia,2NVTV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3908_0	929713.NIASO_14655	0.0	1162.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPMB@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_3908_2	929713.NIASO_14660	8.805e-104	349.0	28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,1ISNF@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
HKD1_k127_3908_1	1185876.BN8_00259	1.762e-201	653.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3932358_2	925409.KI911562_gene612	2.239e-199	625.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_3932358_0	760192.Halhy_5408	6.345e-224	709.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD1_k127_3932358_3	700598.Niako_6461	1.676e-88	294.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3932358_7	1492737.FEM08_21720	1.982e-18	94.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3932358_1	700598.Niako_6463	1.109e-212	671.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
HKD1_k127_3932358_6	700598.Niako_6464	7.493e-57	205.0	COG3548@1|root,COG3548@2|Bacteria,4NUEI@976|Bacteroidetes,1IYQ6@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_3932358_5	700598.Niako_6466	1.844e-58	215.0	2E602@1|root,330PE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3932358_4	700598.Niako_6467	5.699e-79	269.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
HKD1_k127_3948578_1	269798.CHU_2888	2.212e-59	217.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47M4P@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 4	rfe	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
HKD1_k127_3948578_0	700598.Niako_7307	7.885e-314	974.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD1_k127_3948578_2	700598.Niako_7304	4.827e-25	108.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
HKD1_k127_3959231_2	485918.Cpin_5496	1.424e-126	411.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD1_k127_3959231_4	1123248.KB893316_gene4517	7.204e-53	189.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
HKD1_k127_3959231_1	313606.M23134_06773	2.702e-184	629.0	COG2911@1|root,COG3291@1|root,COG4447@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_3959231_3	1279009.ADICEAN_00484	1.784e-62	247.0	COG3227@1|root,COG4409@1|root,COG3227@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
HKD1_k127_3959231_0	925409.KI911562_gene2347	2.383e-263	816.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD1_k127_3976791_1	880073.Calab_1270	1.312e-51	202.0	2ENA5@1|root,33FXV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3976791_2	880073.Calab_1269	3.911e-34	138.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
HKD1_k127_3976791_0	880073.Calab_1268	3.104e-90	306.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
HKD1_k127_3990351_0	700598.Niako_0114	1.96e-321	998.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HKD1_k127_3990351_1	1267211.KI669560_gene2204	2.919e-130	420.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1INX0@117747|Sphingobacteriia	976|Bacteroidetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
HKD1_k127_3990351_2	1122605.KB893645_gene987	2.377e-121	394.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1ISQ1@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD1_k127_3990351_3	700598.Niako_4516	1.781e-24	107.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD1_k127_4016426_1	925409.KI911562_gene1714	5.493e-136	437.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IS3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_3,HlyD_D23
HKD1_k127_4016426_0	925409.KI911562_gene1715	5.664e-175	557.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IPFI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
HKD1_k127_4016426_2	761193.Runsl_5947	6.469e-80	278.0	COG4409@1|root,COG4409@2|Bacteria,4NNBF@976|Bacteroidetes,47TQH@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
HKD1_k127_4027170_5	700598.Niako_5798	1.635e-36	140.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
HKD1_k127_4027170_1	700598.Niako_5799	3.296e-180	575.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1ISIT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HKD1_k127_4027170_3	700598.Niako_5800	5.077e-74	254.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1IS94@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD1_k127_4027170_2	929713.NIASO_16680	5.085e-178	566.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
HKD1_k127_4027170_0	929713.NIASO_16685	3.608e-192	606.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1IQGD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
HKD1_k127_4027170_4	1123278.KB893444_gene1674	6.548e-37	143.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_4028955_0	700598.Niako_6022	3.111e-118	382.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1INQC@117747|Sphingobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD1_k127_4028955_1	1267211.KI669560_gene193	3.174e-37	142.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1IU5M@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
HKD1_k127_4028955_2	1267211.KI669560_gene194	1.252e-34	134.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD1_k127_4042655_2	700598.Niako_6382	0.0004132	44.0	COG0071@1|root,COG0071@2|Bacteria,4NVZT@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HKD1_k127_4042655_0	700598.Niako_5069	2.864e-193	613.0	COG1858@1|root,COG1858@2|Bacteria,4NM2S@976|Bacteroidetes,1IVVD@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD1_k127_4042655_1	1454007.JAUG01000083_gene2258	1.793e-96	321.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1IPHU@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD1_k127_4043762_1	925409.KI911562_gene2891	1.211e-165	527.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
HKD1_k127_4043762_3	929713.NIASO_00860	2.354e-64	224.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD1_k127_4043762_2	1123248.KB893330_gene395	6.815e-107	356.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1IXKD@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
HKD1_k127_4043762_0	1123248.KB893330_gene394	2.353e-303	936.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_4043762_4	485918.Cpin_2704	8.553e-52	184.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
HKD1_k127_4045556_1	1121887.AUDK01000009_gene1233	5.057e-75	257.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2NTGW@237|Flavobacterium	976|Bacteroidetes	EU	Peptidase S9	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD1_k127_4045556_7	1249997.JHZW01000003_gene2701	6.316e-05	54.0	COG3391@1|root,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1IG7V@117743|Flavobacteriia,2PIJB@252356|Maribacter	976|Bacteroidetes	S	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TIG
HKD1_k127_4045556_2	1123277.KB893174_gene6003	3.019e-68	238.0	COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,47QHP@768503|Cytophagia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
HKD1_k127_4045556_4	700598.Niako_0643	5.234e-57	213.0	COG2972@1|root,COG2972@2|Bacteria,4NIRC@976|Bacteroidetes,1J05H@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD1_k127_4045556_0	1123277.KB893195_gene5658	2.735e-75	260.0	COG3279@1|root,COG3279@2|Bacteria,4NF8U@976|Bacteroidetes,47Q2C@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_4045556_5	1123248.KB893321_gene522	2.448e-33	132.0	COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,1IZMV@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD1_k127_4045556_3	641526.ADIWIN_2413	4.667e-63	222.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia	976|Bacteroidetes	S	YeeE YedE family	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD1_k127_4045556_6	1538644.KO02_01995	1.12e-19	89.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1ISKN@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD1_k127_4060072_3	925409.KI911562_gene2912	6.173e-125	407.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
HKD1_k127_4060072_1	700598.Niako_4493	7.726e-176	560.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD1_k127_4060072_2	485918.Cpin_1819	2.246e-154	494.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_4060072_0	1122605.KB893627_gene2875	2.174e-176	559.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1IP4B@117747|Sphingobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
HKD1_k127_4060072_4	700598.Niako_0364	1.412e-86	291.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1IT1P@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD1_k127_4060072_5	700598.Niako_0365	1.459e-33	131.0	COG0106@1|root,COG0454@1|root,COG0106@2|Bacteria,COG0454@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD1_k127_4060095_2	1239962.C943_02031	6.929e-28	116.0	2ED24@1|root,336Z2@2|Bacteria,4P3G3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4060095_0	1123248.KB893370_gene5152	1.471e-264	821.0	COG3011@1|root,COG3011@2|Bacteria,4P6C6@976|Bacteroidetes	976|Bacteroidetes	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
HKD1_k127_4060095_1	1121920.AUAU01000007_gene543	3.351e-57	201.0	COG0604@1|root,COG0604@2|Bacteria,3Y4X4@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD1_k127_4066539_3	700598.Niako_5678	6.707e-07	57.0	2CEPF@1|root,2ZR55@2|Bacteria,4P826@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4066539_1	1408813.AYMG01000015_gene5030	2.297e-31	129.0	COG0454@1|root,COG0454@2|Bacteria,4NWCY@976|Bacteroidetes,1IYX6@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_4066539_0	700598.Niako_2553	0.0	1062.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HKD1_k127_4066539_2	1123242.JH636435_gene2744	1.247e-20	106.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	2|Bacteria	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD1_k127_4069416_0	700598.Niako_5071	0.0	1011.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
HKD1_k127_4069416_2	700598.Niako_5098	4.217e-66	236.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1IS9J@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_4069416_1	1123248.KB893337_gene2554	3.181e-75	254.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,4NDUW@976|Bacteroidetes,1IQ7T@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD1_k127_4074152_1	929713.NIASO_12570	8.228e-100	330.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,1IXAV@117747|Sphingobacteriia	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HKD1_k127_4074152_0	929713.NIASO_12545	8.024e-303	939.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1INVS@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_4074152_2	1123248.KB893331_gene3742	1.009e-41	157.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes,1INW3@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD1_k127_4108898_3	700598.Niako_7335	5.99e-54	190.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD1_k127_4108898_2	760192.Halhy_2813	1.576e-66	229.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD1_k127_4108898_0	1123248.KB893315_gene3085	1.484e-144	467.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,1IPIR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Alanine racemase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
HKD1_k127_4108898_1	1123248.KB893315_gene3084	6.279e-87	290.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,1IRCG@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD1_k127_4109096_2	1122605.KB893647_gene351	9.322e-84	279.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1INQC@117747|Sphingobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD1_k127_4109096_1	700598.Niako_6021	3.582e-122	395.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD1_k127_4109096_3	1392490.JHZX01000001_gene137	2.464e-79	273.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1I0H0@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD1_k127_4109096_0	925409.KI911562_gene473	0.0	1185.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1J0KU@117747|Sphingobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
HKD1_k127_4113680_1	485918.Cpin_1632	4.971e-74	250.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HKD1_k127_4113680_3	700598.Niako_4665	3.544e-25	106.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1IUA3@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HKD1_k127_4113680_2	1267211.KI669560_gene1336	1.091e-63	222.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1IRSX@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HKD1_k127_4113680_0	1123248.KB893314_gene3305	3.018e-162	517.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1IPEC@117747|Sphingobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HKD1_k127_4120865_5	700598.Niako_6026	2.187e-97	323.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1IW6H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
HKD1_k127_4120865_9	700598.Niako_6028	5.386e-40	161.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_2
HKD1_k127_4120865_3	700598.Niako_6029	9.814e-127	407.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD1_k127_4120865_1	1122605.KB893646_gene56	4.272e-138	444.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD1_k127_4120865_0	929713.NIASO_13835	1.462e-139	448.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1IQSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD1_k127_4120865_7	929713.NIASO_13840	7.556e-65	223.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD1_k127_4120865_6	1123248.KB893319_gene4040	4.252e-74	250.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD1_k127_4120865_10	925409.KI911562_gene586	8.289e-31	123.0	COG4680@1|root,COG4680@2|Bacteria,4NVGW@976|Bacteroidetes,1IZD4@117747|Sphingobacteriia	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
HKD1_k127_4120865_8	925409.KI911562_gene587	9.277e-45	166.0	COG5499@1|root,COG5499@2|Bacteria,4NTXQ@976|Bacteroidetes,1IYP6@117747|Sphingobacteriia	976|Bacteroidetes	K	transcription regulator containing HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4120865_2	929556.Solca_3885	1.842e-134	438.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1IQQV@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HKD1_k127_4120865_4	700598.Niako_6039	1.409e-111	362.0	COG2316@1|root,COG2316@2|Bacteria,4NIAC@976|Bacteroidetes,1IPCJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_4123306_1	929556.Solca_4205	0.0007843	43.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPE6@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD1_k127_4123306_0	929556.Solca_4206	1.045e-102	346.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,1INTJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD1_k127_4134907_1	1270196.JCKI01000001_gene4122	3.387e-192	602.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1INMA@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
HKD1_k127_4134907_0	700598.Niako_5295	2.526e-241	753.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1IQ2E@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
HKD1_k127_4134907_2	929713.NIASO_18740	6.237e-185	581.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1IP33@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HKD1_k127_4150650_11	700598.Niako_5600	7.325e-54	201.0	COG0741@1|root,COG0741@2|Bacteria,4NEKW@976|Bacteroidetes,1IRNH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HKD1_k127_4150650_1	1267211.KI669560_gene1618	1.052e-262	816.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S10	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
HKD1_k127_4150650_5	700598.Niako_2157	2.669e-181	578.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,1IPI1@117747|Sphingobacteriia	976|Bacteroidetes	S	Sialate O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
HKD1_k127_4150650_10	468059.AUHA01000002_gene49	9.509e-61	216.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1IT61@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD1_k127_4150650_12	1122605.KB893637_gene3296	1.199e-33	132.0	COG0724@1|root,COG0724@2|Bacteria,4NUIS@976|Bacteroidetes,1ITB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD1_k127_4150650_9	1122605.KB893625_gene1602	2.181e-76	261.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
HKD1_k127_4150650_0	1122605.KB893625_gene1601	0.0	1454.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HKD1_k127_4150650_6	700598.Niako_0970	6.991e-117	388.0	COG1680@1|root,COG1680@2|Bacteria,4NJ9H@976|Bacteroidetes,1ISUH@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_4150650_2	760192.Halhy_1263	5.005e-211	670.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD1_k127_4150650_7	929562.Emtol_4120	9.315e-113	379.0	COG0153@1|root,COG0153@2|Bacteria	2|Bacteria	G	galactokinase activity	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD1_k127_4150650_8	525904.Tter_2204	2.48e-92	315.0	COG1085@1|root,COG1085@2|Bacteria,2NQA3@2323|unclassified Bacteria	2|Bacteria	H	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
HKD1_k127_4150650_3	1121957.ATVL01000010_gene556	3.274e-198	629.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,47KIK@768503|Cytophagia	976|Bacteroidetes	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB_2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
HKD1_k127_4150650_13	697282.Mettu_3684	2.36e-29	120.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4150650_4	485918.Cpin_4000	3.534e-182	587.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1IPDU@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
HKD1_k127_4153244_0	925409.KI911562_gene2818	0.0	1293.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HKD1_k127_4153244_3	1123248.KB893315_gene3102	3.097e-79	276.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
HKD1_k127_4153244_6	700598.Niako_4936	1.291e-54	194.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1ISEQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HKD1_k127_4153244_4	1123248.KB893381_gene1096	5.42e-77	261.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HKD1_k127_4153244_1	1122605.KB893649_gene3839	7.296e-124	399.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1IPE4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HKD1_k127_4153244_2	1122605.KB893649_gene3840	4.033e-85	282.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HKD1_k127_4153244_5	929556.Solca_1833	1.44e-56	200.0	COG4320@1|root,COG4320@2|Bacteria,4NWZ0@976|Bacteroidetes,1J15W@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
HKD1_k127_4154873_1	1123248.KB893350_gene2906	4.682e-69	237.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD1_k127_4154873_0	1123248.KB893350_gene2906	1.251e-154	510.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD1_k127_4154873_2	929713.NIASO_20205	4.86e-58	204.0	COG1943@1|root,COG1943@2|Bacteria,4NR8E@976|Bacteroidetes	976|Bacteroidetes	L	Pfam Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD1_k127_4179505_1	925409.KI911562_gene941	1.508e-68	235.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
HKD1_k127_4179505_3	1089547.KB913013_gene4646	3.97e-52	191.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,47XS3@768503|Cytophagia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
HKD1_k127_4179505_0	925409.KI911562_gene940	0.0	1183.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1IQ1B@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome C oxidase subunit II, periplasmic domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD1_k127_4179505_2	925409.KI911562_gene939	8.749e-64	224.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1IY7U@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD1_k127_4179505_4	1279009.ADICEAN_01928	8.777e-30	123.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47RNG@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD1_k127_4179505_5	925409.KI911562_gene938	4.408e-18	87.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
HKD1_k127_4196710_0	700598.Niako_1539	0.0	1050.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
HKD1_k127_4196710_2	700598.Niako_5467	7.361e-43	160.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1ITHS@117747|Sphingobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_4196710_1	700598.Niako_1542	1.471e-57	208.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD1_k127_4216978_3	755732.Fluta_2051	2.577e-60	222.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
HKD1_k127_4216978_1	929713.NIASO_17675	3.392e-144	460.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD1_k127_4216978_2	925409.KI911562_gene1461	4.056e-120	390.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
HKD1_k127_4216978_0	700598.Niako_5685	0.0	1745.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IRF8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
HKD1_k127_4245612_2	1123277.KB893177_gene3609	4.749e-11	64.0	COG3403@1|root,COG3403@2|Bacteria,4PNZ7@976|Bacteroidetes,47YRG@768503|Cytophagia	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4245612_0	1123248.KB893324_gene1698	4.85e-160	511.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1J098@117747|Sphingobacteriia	976|Bacteroidetes	P	Di-haem cytochrome c peroxidase	ccp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
HKD1_k127_4245612_1	714943.Mucpa_1801	1.36e-94	318.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1ITYF@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_4249692_0	929562.Emtol_2210	2.694e-286	891.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47NJB@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
HKD1_k127_4249692_2	1237149.C900_00817	3.572e-20	96.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD1_k127_4249692_1	714943.Mucpa_4119	3.153e-20	93.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1IPH9@117747|Sphingobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD1_k127_4262816_3	1123248.KB893315_gene3119	2.946e-33	131.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1IQ34@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HKD1_k127_4262816_0	700598.Niako_1526	6.652e-149	475.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1IPR7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
HKD1_k127_4262816_2	1122605.KB893631_gene3900	1.137e-87	308.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
HKD1_k127_4262816_1	925409.KI911562_gene2664	1.736e-136	436.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD1_k127_4263289_12	700598.Niako_6846	1.282e-62	220.0	COG1566@1|root,COG1566@2|Bacteria,4PMCY@976|Bacteroidetes,1J0U2@117747|Sphingobacteriia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
HKD1_k127_4263289_4	700598.Niako_6847	6.471e-156	498.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD1_k127_4263289_5	700598.Niako_6849	4.787e-150	482.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD1_k127_4263289_3	700598.Niako_6850	1.688e-192	617.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1J0U3@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
HKD1_k127_4263289_13	700598.Niako_6851	4.541e-46	178.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
HKD1_k127_4263289_14	700598.Niako_6852	7.445e-22	97.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD1_k127_4263289_7	700598.Niako_6852	2.876e-103	337.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
HKD1_k127_4263289_0	700598.Niako_6853	1.303e-280	877.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
HKD1_k127_4263289_2	700598.Niako_6854	4.077e-220	689.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD1_k127_4263289_10	700598.Niako_6855	9.491e-79	271.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1ISRG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4263289_6	1123248.KB893359_gene2110	2.075e-118	398.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
HKD1_k127_4263289_9	1123248.KB893359_gene2109	1.43e-92	315.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4263289_1	929713.NIASO_19340	3.463e-253	795.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD1_k127_4263289_8	700598.Niako_6861	4.493e-99	326.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_4263289_15	929556.Solca_4056	1.093e-18	89.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1IPUD@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_427189_6	153721.MYP_1603	3.042e-07	58.0	2EEXX@1|root,338RA@2|Bacteria,4NV50@976|Bacteroidetes,47WS6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_427189_5	1077972.ARGLB_008_00440	9.679e-17	86.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD1_k127_427189_2	700598.Niako_4119	1.234e-130	426.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,1IPA7@117747|Sphingobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_427189_3	1123248.KB893315_gene3223	2.989e-125	408.0	COG3291@1|root,COG3291@2|Bacteria,4NH7R@976|Bacteroidetes,1IWQY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD1_k127_427189_0	1237149.C900_04258	2.136e-159	505.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47JVM@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD1_k127_427189_4	700598.Niako_3441	6.293e-32	126.0	COG1977@1|root,COG1977@2|Bacteria,4NVP9@976|Bacteroidetes	976|Bacteroidetes	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
HKD1_k127_427189_1	700598.Niako_3442	3.843e-151	480.0	COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4277612_2	1123277.KB893172_gene575	6.098e-30	122.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_4277612_1	929713.NIASO_04945	2.024e-266	842.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_4277612_0	929556.Solca_0266	0.0	1055.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_4277753_3	700598.Niako_6343	7.807e-33	129.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1IS0K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
HKD1_k127_4277753_0	929562.Emtol_2257	0.0	1091.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47M4N@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
HKD1_k127_4277753_1	1123277.KB893239_gene1210	1.194e-272	842.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,47KYW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD1_k127_4277753_2	1089547.KB913013_gene4649	4.225e-35	139.0	COG4886@1|root,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47P4Q@768503|Cytophagia	976|Bacteroidetes	S	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
HKD1_k127_428917_0	1237149.C900_04326	7.606e-98	342.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HKD1_k127_428917_1	160799.PBOR_06635	2.607e-30	127.0	COG0826@1|root,COG0826@2|Bacteria,1UYPK@1239|Firmicutes,4HW2A@91061|Bacilli,26WVP@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
HKD1_k127_4289196_2	700598.Niako_5082	5.002e-52	185.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1IQ02@117747|Sphingobacteriia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD1_k127_4289196_0	929713.NIASO_19235	4.888e-99	325.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD1_k127_4289196_1	1122605.KB893632_gene4391	1.317e-63	220.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes	976|Bacteroidetes	H	Pfam 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD1_k127_4289196_3	929713.NIASO_19245	5.764e-37	140.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD1_k127_4290444_2	700598.Niako_2039	5.709e-50	191.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1IXPB@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_4290444_3	143224.JQMD01000002_gene2496	6.794e-49	188.0	COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_4290444_0	700598.Niako_2039	8.675e-120	388.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1IXPB@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_4290444_4	1123248.KB893337_gene2423	7.55e-33	134.0	2DWTR@1|root,341UH@2|Bacteria,4P4RF@976|Bacteroidetes,1IYRR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4290444_1	700598.Niako_5047	2.577e-90	300.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD1_k127_4290786_3	700598.Niako_2546	1.556e-130	422.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_4290786_4	760192.Halhy_0734	2.363e-23	103.0	COG1487@1|root,COG1487@2|Bacteria,4NWXJ@976|Bacteroidetes,1J02R@117747|Sphingobacteriia	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
HKD1_k127_4290786_1	929713.NIASO_09020	7.647e-160	507.0	COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,1J0R0@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_4290786_6	926551.KB900709_gene1117	3.299e-05	53.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,1I2ZA@117743|Flavobacteriia,1ERWF@1016|Capnocytophaga	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
HKD1_k127_4290786_0	700598.Niako_2543	6.81e-177	563.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD1_k127_4290786_2	925409.KI911562_gene1603	1.674e-151	485.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD1_k127_4292714_1	1122605.KB893626_gene2534	7.211e-110	362.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
HKD1_k127_4292714_0	700598.Niako_5719	1.524e-163	524.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD1_k127_4292714_2	700598.Niako_5720	8.462e-45	163.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
HKD1_k127_4303353_3	1122605.KB893643_gene701	5.387e-161	511.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1IPSI@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
HKD1_k127_4303353_2	1267211.KI669560_gene1711	3.475e-232	732.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IQ32@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
HKD1_k127_4303353_0	700598.Niako_3958	1.993e-290	902.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD1_k127_4303353_11	925409.KI911562_gene777	2.125e-53	192.0	COG3631@1|root,COG3631@2|Bacteria,4NQGX@976|Bacteroidetes,1IXWE@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HKD1_k127_4303353_5	694427.Palpr_1039	8.588e-130	420.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,2FQT2@200643|Bacteroidia,22WM3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
HKD1_k127_4303353_7	929562.Emtol_2416	3.895e-109	357.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
HKD1_k127_4303353_9	925409.KI911562_gene641	2.625e-76	260.0	COG0431@1|root,COG0431@2|Bacteria,4NNY7@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_4303353_4	1122605.KB893643_gene698	5.895e-151	484.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1IQZS@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
HKD1_k127_4303353_8	1123248.KB893315_gene3184	8.742e-85	288.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1IRTX@117747|Sphingobacteriia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
HKD1_k127_4303353_6	925409.KI911562_gene921	7.413e-113	370.0	COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,1ISEM@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_4303353_10	700598.Niako_6252	5.379e-60	212.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD1_k127_4303353_1	925409.KI911562_gene1585	9.488e-243	755.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IV39@117747|Sphingobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
HKD1_k127_4314079_1	504472.Slin_2449	5.56e-116	379.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD1_k127_4314079_2	1279009.ADICEAN_00420	1.768e-38	148.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
HKD1_k127_4314079_3	1122605.KB893643_gene741	7.53e-28	114.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD1_k127_4314079_5	929556.Solca_0522	2.488e-11	66.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4314079_0	929556.Solca_0522	1.989e-133	429.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4319268_2	700598.Niako_1158	1.659e-39	152.0	COG0642@1|root,COG2205@2|Bacteria,4NK0U@976|Bacteroidetes,1IQHZ@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,SBP_bac_3
HKD1_k127_4319268_1	700598.Niako_1547	2.144e-158	504.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD1_k127_4319268_0	929713.NIASO_06810	1.162e-292	929.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_4319268_3	700598.Niako_0900	7.397e-15	77.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4319663_2	398512.JQKC01000024_gene3186	1.769e-16	94.0	COG0265@1|root,COG1524@1|root,COG2755@1|root,COG3507@1|root,COG0265@2|Bacteria,COG1524@2|Bacteria,COG2755@2|Bacteria,COG3507@2|Bacteria,1UY9N@1239|Firmicutes,24E52@186801|Clostridia	186801|Clostridia	O	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	SLH
HKD1_k127_4319663_0	1894.JOER01000003_gene2865	1.912e-140	469.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
HKD1_k127_4319663_3	700598.Niako_5678	6.707e-07	57.0	2CEPF@1|root,2ZR55@2|Bacteria,4P826@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4319663_1	1408813.AYMG01000015_gene5030	3.564e-30	127.0	COG0454@1|root,COG0454@2|Bacteria,4NWCY@976|Bacteroidetes,1IYX6@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_4322326_0	1121373.KB903664_gene2651	1.03e-165	546.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4338227_3	700598.Niako_5643	1.464e-50	182.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD1_k127_4338227_2	1122605.KB893646_gene177	7.681e-51	185.0	2DRB4@1|root,33B1T@2|Bacteria	2|Bacteria	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
HKD1_k127_4338227_1	1122605.KB893646_gene176	3.89e-75	260.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1IS92@117747|Sphingobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HKD1_k127_4338227_0	925409.KI911562_gene1439	0.0	1061.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD1_k127_4343447_1	1122605.KB893626_gene2579	4.115e-116	378.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1IPG1@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD1_k127_4343447_2	1131812.JQMS01000001_gene2773	4.732e-59	213.0	COG0671@1|root,COG0671@2|Bacteria,4NJEX@976|Bacteroidetes,1I2RP@117743|Flavobacteriia,2NSJM@237|Flavobacterium	976|Bacteroidetes	I	PA-phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_4343447_0	700598.Niako_4232	0.0	1506.0	COG0841@1|root,COG0841@2|Bacteria,4NGVM@976|Bacteroidetes,1IQ7W@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD1_k127_4343447_3	1123248.KB893326_gene1283	7.431e-46	169.0	COG0845@1|root,COG0845@2|Bacteria,4NMQS@976|Bacteroidetes,1IVBH@117747|Sphingobacteriia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD1_k127_4363394_0	558152.IQ37_06895	3.359e-182	580.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,3ZQ0I@59732|Chryseobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD1_k127_4363394_2	1123248.KB893326_gene1461	5.066e-12	70.0	COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,1IRK6@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
HKD1_k127_4363394_1	880071.Fleli_3261	2.203e-27	119.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
HKD1_k127_4371796_1	1313301.AUGC01000020_gene706	1.079e-22	97.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HKD1_k127_4371796_0	1122605.KB893637_gene3086	0.0	1276.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
HKD1_k127_4377445_1	925409.KI911562_gene2162	1.545e-50	182.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HKD1_k127_4377445_0	700598.Niako_1138	1.438e-266	823.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
HKD1_k127_4377445_2	1286632.P278_26490	5.485e-28	119.0	COG4319@1|root,COG4319@2|Bacteria,4NTU3@976|Bacteroidetes,1I52V@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD1_k127_4377445_3	1267533.KB906737_gene1972	1.162e-20	96.0	COG1359@1|root,COG1359@2|Bacteria,3Y5IV@57723|Acidobacteria,2JNI6@204432|Acidobacteriia	204432|Acidobacteriia	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_437955_6	700598.Niako_6109	5.663e-39	153.0	COG1595@1|root,COG1595@2|Bacteria,4NR0P@976|Bacteroidetes,1J0AP@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_437955_4	1267211.KI669560_gene1620	1.193e-61	226.0	COG3712@1|root,COG3712@2|Bacteria,4NM0I@976|Bacteroidetes	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
HKD1_k127_437955_0	929713.NIASO_15935	0.0	1240.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_437955_2	929713.NIASO_15930	2.201e-199	632.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IPKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD1_k127_437955_3	1123248.KB893314_gene3674	2.467e-119	397.0	COG3303@1|root,COG3303@2|Bacteria,4PKHF@976|Bacteroidetes,1J0P8@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
HKD1_k127_437955_1	1123248.KB893326_gene1293	8.144e-269	838.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD1_k127_4417216_0	485918.Cpin_1305	5.371e-221	692.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD1_k127_4417216_2	465817.ETA_06390	2.307e-14	75.0	2BQNH@1|root,32JIU@2|Bacteria,1MY96@1224|Proteobacteria,1S7FT@1236|Gammaproteobacteria,3X792@551|Erwinia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4419260_0	1122605.KB893626_gene2811	5.227e-83	284.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD1_k127_4419260_1	925409.KI911562_gene1028	2.668e-79	269.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ITGM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
HKD1_k127_4419463_1	1168289.AJKI01000053_gene817	6.096e-11	69.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	CBM_11,Cellulase
HKD1_k127_4419463_2	382464.ABSI01000001_gene4220	9.166e-09	67.0	2AAZX@1|root,310DH@2|Bacteria,46V0B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4419463_0	700598.Niako_7334	1.608e-21	96.0	COG2084@1|root,COG2084@2|Bacteria,4NEF7@976|Bacteroidetes,1IS6B@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
HKD1_k127_4422240_3	871968.DESME_02145	2.818e-12	69.0	COG0454@1|root,COG0456@2|Bacteria,1VHVK@1239|Firmicutes,25E0E@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_4422240_0	330214.NIDE2514	5.061e-74	264.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
HKD1_k127_4422240_2	929562.Emtol_0586	2.08e-25	108.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47R62@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_4422240_1	1267211.KI669560_gene870	6.993e-35	138.0	2CH3Z@1|root,32RP9@2|Bacteria,4NQUA@976|Bacteroidetes,1IYRN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
HKD1_k127_4422240_4	89187.ISM_14165	4.15e-06	51.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria,46PBV@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	znuB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HKD1_k127_4422296_1	1123248.KB893359_gene2164	2.303e-18	86.0	2EPP0@1|root,33H9M@2|Bacteria,4NXT6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4422296_0	1121904.ARBP01000009_gene4135	6.877e-33	141.0	COG0248@1|root,COG0248@2|Bacteria,4NNBU@976|Bacteroidetes,47PMG@768503|Cytophagia	976|Bacteroidetes	FP	Ppx GppA phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
HKD1_k127_4422296_2	1267211.KI669560_gene1850	2.752e-16	83.0	2DNWS@1|root,32ZK9@2|Bacteria,4NUTW@976|Bacteroidetes,1IZWH@117747|Sphingobacteriia	976|Bacteroidetes	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
HKD1_k127_4430575_2	700598.Niako_2922	1.153e-154	492.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1IQK5@117747|Sphingobacteriia	976|Bacteroidetes	H	Sigma-54 interaction domain	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
HKD1_k127_4430575_1	700598.Niako_2921	2.158e-219	682.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1INMN@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
HKD1_k127_4430575_0	1122605.KB893627_gene2867	0.0	1116.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IX43@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
HKD1_k127_4430575_3	641524.ADICYQ_3233	1.118e-20	92.0	COG4502@1|root,COG4502@2|Bacteria,4NQDT@976|Bacteroidetes,47QKD@768503|Cytophagia	976|Bacteroidetes	S	PFAM 5 nucleotidase deoxy	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
HKD1_k127_4442283_2	1123248.KB893337_gene2553	5.93e-47	173.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD1_k127_4442283_1	1123248.KB893359_gene2143	3.68e-70	243.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1ISD6@117747|Sphingobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD1_k127_4442283_0	929713.NIASO_05690	3.474e-148	478.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
HKD1_k127_4447572_5	1267211.KI669560_gene1655	3.014e-22	98.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD1_k127_4447572_1	1122605.KB893633_gene4278	2.348e-102	343.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1IP2P@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD1_k127_4447572_4	1267211.KI669560_gene1657	4.778e-28	117.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1ITYX@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD1_k127_4447572_3	929713.NIASO_03990	7.632e-39	155.0	2DPQE@1|root,332Z6@2|Bacteria,4NXFJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4447572_2	1267211.KI669560_gene1659	9.692e-45	168.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
HKD1_k127_4447572_0	700598.Niako_1191	8.926e-167	530.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
HKD1_k127_4447631_0	1122605.KB893625_gene2045	1.853e-289	910.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
HKD1_k127_4447631_2	925409.KI911562_gene2109	2.02e-48	176.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
HKD1_k127_4447631_1	925409.KI911562_gene2108	1.235e-167	532.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV0I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD1_k127_4453752_2	694427.Palpr_2004	3.232e-56	199.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,22WBP@171551|Porphyromonadaceae	976|Bacteroidetes	G	Fibronectin type III-like domain	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD1_k127_4453752_0	1123248.KB893381_gene954	1.178e-201	642.0	COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes,1IRBT@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
HKD1_k127_4453752_3	1123248.KB893381_gene954	5.424e-18	84.0	COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes,1IRBT@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
HKD1_k127_4453752_1	929556.Solca_0314	1.229e-156	499.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQK1@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD1_k127_4457185_2	485918.Cpin_1982	5.475e-106	347.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1INV1@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HKD1_k127_4457185_3	485918.Cpin_1984	6.648e-82	277.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1IQ0S@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HKD1_k127_4457185_0	700598.Niako_0101	1.597e-186	588.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1INYR@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD1_k127_4457185_1	1267211.KI669560_gene158	3.824e-113	374.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1IPAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD1_k127_4467083_1	1191523.MROS_1709	1.133e-47	180.0	28PU4@1|root,2ZCF6@2|Bacteria	2|Bacteria	-	-	nrfJ	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4467083_0	269799.Gmet_2899	6.472e-68	244.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
HKD1_k127_4467083_2	880073.Calab_1270	1.524e-14	80.0	2ENA5@1|root,33FXV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4471980_0	1267211.KI669560_gene1852	5.65e-110	357.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INWZ@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase S9 prolyl oligopeptidase active site domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
HKD1_k127_4471980_1	925409.KI911562_gene2303	2.441e-83	282.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1INT9@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD1_k127_4479794_1	925409.KI911562_gene2935	4.638e-211	664.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HKD1_k127_4479794_4	700598.Niako_0335	3.285e-50	181.0	COG2940@1|root,COG2940@2|Bacteria,4P66M@976|Bacteroidetes,1IYW5@117747|Sphingobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
HKD1_k127_4479794_6	1121373.KB903642_gene3693	0.0001019	51.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Fasciclin
HKD1_k127_4479794_2	700598.Niako_4439	3.442e-140	456.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1IYZU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HKD1_k127_4479794_0	1122605.KB893645_gene1028	0.0	1374.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD1_k127_4479794_3	1122605.KB893645_gene1031	1.011e-76	263.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1IS2Z@117747|Sphingobacteriia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HKD1_k127_4479794_5	1122176.KB903531_gene2774	1.493e-28	117.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
HKD1_k127_4489605_2	1191523.MROS_1708	2.067e-42	156.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	asdII	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HKD1_k127_4489605_3	926549.KI421517_gene2389	5.856e-24	102.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,47JK0@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HKD1_k127_4489605_0	509635.N824_15670	1.136e-124	407.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
HKD1_k127_4489605_1	926549.KI421517_gene1668	1.75e-49	179.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_4493050_4	1122137.AQXF01000003_gene2214	1.411e-102	345.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
HKD1_k127_4493050_3	1317122.ATO12_13335	9.761e-105	347.0	COG4989@1|root,COG4989@2|Bacteria,4NENV@976|Bacteroidetes,1HY8B@117743|Flavobacteriia,2YH11@290174|Aquimarina	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD1_k127_4493050_7	1122605.KB893644_gene1518	4.158e-48	175.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1ITMI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD1_k127_4493050_5	1122605.KB893644_gene1519	5.576e-67	231.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD1_k127_4493050_8	1122605.KB893644_gene1520	2.491e-43	158.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1ISSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD1_k127_4493050_6	929713.NIASO_18860	1.01e-56	201.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1ISJI@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD1_k127_4493050_9	485918.Cpin_1724	2.215e-26	117.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_4
HKD1_k127_4493050_0	1122605.KB893644_gene1523	1.225e-262	819.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD1_k127_4493050_2	1122605.KB893644_gene1524	1.134e-132	430.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD1_k127_4493050_1	700598.Niako_5113	2.937e-182	586.0	COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
HKD1_k127_4493050_10	929713.NIASO_19285	0.0001411	45.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HKD1_k127_4497190_1	1122605.KB893627_gene2928	4.319e-190	605.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD1_k127_4497190_0	700598.Niako_0407	6.862e-297	932.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
HKD1_k127_4497190_4	485918.Cpin_0317	2.047e-08	56.0	COG0330@1|root,COG0330@2|Bacteria,4NHU9@976|Bacteroidetes,1IQT9@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD1_k127_4497190_3	491205.JARQ01000007_gene3030	1.376e-11	66.0	COG0330@1|root,COG0330@2|Bacteria,4NHU9@976|Bacteroidetes,1HXK0@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD1_k127_4497190_2	700598.Niako_0406	4.561e-149	482.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
HKD1_k127_4500647_3	929713.NIASO_03735	1.673e-147	469.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1IRAS@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HKD1_k127_4500647_2	1122605.KB893625_gene2287	1.723e-181	575.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
HKD1_k127_4500647_5	700598.Niako_4655	5.021e-84	280.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD1_k127_4500647_4	700598.Niako_4656	7.435e-123	398.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD1_k127_4500647_0	700598.Niako_4659	0.0	1065.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HKD1_k127_4500647_1	1123248.KB893315_gene2997	1.649e-182	579.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD1_k127_4503482_0	700598.Niako_2097	4.404e-207	646.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD1_k127_4503482_2	700598.Niako_1816	3.481e-81	276.0	COG4430@1|root,COG4430@2|Bacteria,4NU4U@976|Bacteroidetes,1ITCA@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
HKD1_k127_4503482_4	700598.Niako_2102	3.385e-57	201.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	pocR	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR,Response_reg,Sigma54_activ_2
HKD1_k127_4503482_3	700598.Niako_2104	2.464e-66	229.0	COG0346@1|root,COG0346@2|Bacteria,4NQXE@976|Bacteroidetes,1IZAF@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD1_k127_4503482_1	1122605.KB893643_gene604	6.141e-152	494.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes,1ISGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
HKD1_k127_4503482_5	925409.KI911562_gene2075	5.606e-49	181.0	COG2246@1|root,COG2246@2|Bacteria,4NSQN@976|Bacteroidetes	976|Bacteroidetes	S	Pfam GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HKD1_k127_4511052_3	1122605.KB893630_gene4063	3.608e-181	576.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD1_k127_4511052_2	1122605.KB893630_gene4062	6.379e-215	674.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD1_k127_4511052_1	1122605.KB893630_gene4061	2.511e-221	691.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD1_k127_4511052_0	700598.Niako_7319	5.51e-247	769.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_4511052_4	929713.NIASO_19565	7.272e-66	229.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD1_k127_4519429_1	700598.Niako_2913	4.122e-77	261.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1INZY@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_4519429_0	1122605.KB893625_gene2339	7.558e-125	405.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
HKD1_k127_4519429_2	1158294.JOMI01000001_gene1583	2.439e-05	47.0	COG4502@1|root,COG4502@2|Bacteria,4NQDT@976|Bacteroidetes,2FSV7@200643|Bacteroidia	976|Bacteroidetes	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
HKD1_k127_45359_0	760192.Halhy_6306	6.672e-176	558.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_4539622_1	700598.Niako_2196	2.397e-151	485.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IP1S@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_4539622_0	694427.Palpr_2629	1.31e-207	654.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,2FM6G@200643|Bacteroidia,22WMY@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_4539622_2	1123234.AUKI01000011_gene1459	2.504e-90	306.0	COG2273@1|root,COG2273@2|Bacteria,4NMEJ@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
HKD1_k127_4539622_3	1123248.KB893324_gene1729	8.063e-42	155.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
HKD1_k127_4539622_4	1267535.KB906767_gene3662	7.324e-07	60.0	COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HKD1_k127_4544256_1	1270196.JCKI01000001_gene4122	1.075e-197	622.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1INMA@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
HKD1_k127_4544256_5	1121895.Q765_09310	1.412e-26	113.0	COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,1I085@117743|Flavobacteriia,2NUQT@237|Flavobacterium	976|Bacteroidetes	G	PFAM Mannitol dehydrogenase C-terminal domain	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
HKD1_k127_4544256_2	616991.JPOO01000001_gene2799	8.479e-156	497.0	COG0673@1|root,COG0673@2|Bacteria,4NEQB@976|Bacteroidetes,1HZ01@117743|Flavobacteriia,23GAT@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	yvaA	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_4544256_4	929713.NIASO_00460	4.823e-52	187.0	COG2905@1|root,COG2905@2|Bacteria,4NTKX@976|Bacteroidetes,1J0SE@117747|Sphingobacteriia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_4544256_0	1122605.KB893645_gene1211	1.784e-321	996.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD1_k127_4544256_3	700598.Niako_1031	2.951e-87	295.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IS23@117747|Sphingobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
HKD1_k127_4545740_1	700598.Niako_1732	2.651e-49	185.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD1_k127_4545740_0	700598.Niako_6677	1.414e-81	277.0	COG2197@1|root,COG2197@2|Bacteria,4NJW3@976|Bacteroidetes,1IS43@117747|Sphingobacteriia	976|Bacteroidetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_4545740_2	485918.Cpin_4291	3.927e-36	141.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_4594421_3	743722.Sph21_2610	7.914e-220	692.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_4594421_0	929556.Solca_0260	0.0	1049.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRAB@117747|Sphingobacteriia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,HTH_18,MacB_PCD
HKD1_k127_4594421_2	1123248.KB893321_gene481	2.36e-317	990.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_4594421_1	761193.Runsl_1946	2.183e-320	1000.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_4594421_4	700598.Niako_1205	7.468e-129	413.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4594421_5	1123248.KB893321_gene483	1.463e-64	222.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
HKD1_k127_4596836_2	1166018.FAES_4917	1.6e-58	207.0	2BXJ3@1|root,32JAR@2|Bacteria,4NQKG@976|Bacteroidetes,47QDD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
HKD1_k127_4596836_1	1123248.KB893325_gene1224	5.673e-64	226.0	arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4596836_0	700598.Niako_1979	3.629e-151	482.0	COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1IRPG@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_4601908_7	1196322.A370_03107	9.853e-07	51.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,24BVW@186801|Clostridia,36GH5@31979|Clostridiaceae	186801|Clostridia	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD1_k127_4601908_3	1123248.KB893385_gene4897	6.279e-50	181.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1IRNM@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
HKD1_k127_4601908_2	1121904.ARBP01000014_gene42	1.548e-61	215.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,47XP2@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
HKD1_k127_4601908_1	1237149.C900_02588	1.791e-80	277.0	COG2267@1|root,COG2267@2|Bacteria,4PN25@976|Bacteroidetes,47Y5W@768503|Cytophagia	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_4601908_6	1502851.FG93_06008	2.029e-21	102.0	COG2849@1|root,COG2849@2|Bacteria,1NFB6@1224|Proteobacteria,2UH63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4601908_4	1408813.AYMG01000025_gene2655	6.438e-42	161.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD1_k127_4601908_0	1279009.ADICEAN_00044	3.018e-94	317.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,47QHI@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_4601908_5	485918.Cpin_4592	8.797e-28	113.0	2E5NA@1|root,330D3@2|Bacteria,4NUZF@976|Bacteroidetes,1IU4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
HKD1_k127_4612171_1	1347393.HG726019_gene7835	1.176e-22	98.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,2FMSQ@200643|Bacteroidia,4AKGR@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD1_k127_4612171_0	929556.Solca_3708	1.213e-235	754.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IPD4@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_4624707_1	1123248.KB893338_gene2311	1.142e-139	458.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IR03@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
HKD1_k127_4624707_2	929713.NIASO_07410	1.441e-118	383.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,1IQ7K@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD1_k127_4624707_0	700598.Niako_5205	2.606e-188	599.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IV3C@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_462765_0	1267211.KI669560_gene348	4.357e-198	624.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_462765_1	925409.KI911562_gene1358	7.176e-101	338.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1IP4P@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_4631701_0	925409.KI911562_gene51	5.171e-173	552.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD1_k127_4631701_1	388413.ALPR1_06310	4.635e-99	334.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,47UKI@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
HKD1_k127_4631701_2	700598.Niako_5270	5.274e-58	207.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes,1IY7V@117747|Sphingobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
HKD1_k127_4631701_3	700598.Niako_2267	4.534e-49	181.0	2DSNU@1|root,33GV1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
HKD1_k127_4631701_4	929562.Emtol_1394	2.387e-46	174.0	COG1943@1|root,COG1943@2|Bacteria,4NQR4@976|Bacteroidetes,47QSX@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD1_k127_4651425_1	1379270.AUXF01000003_gene3550	1.864e-107	355.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_4651425_0	1123248.KB893381_gene1113	2.596e-234	731.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1IP4M@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
HKD1_k127_4651425_3	362418.IW19_12195	1.473e-28	123.0	arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,1IJ37@117743|Flavobacteriia,2P04F@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_465434_3	929556.Solca_3545	0.0002673	53.0	COG2335@1|root,COG2335@2|Bacteria,4NW3U@976|Bacteroidetes,1IUQQ@117747|Sphingobacteriia	976|Bacteroidetes	M	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
HKD1_k127_465434_2	1279009.ADICEAN_02097	1.074e-36	155.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_465434_1	1268072.PSAB_07645	2.983e-50	193.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,26VD8@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_465434_0	1121875.KB907556_gene568	3.852e-114	371.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
HKD1_k127_4657349_3	760192.Halhy_5489	3.871e-12	69.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1ISW6@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD1_k127_4657349_2	700598.Niako_1948	5.662e-77	265.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
HKD1_k127_4657349_0	925409.KI911562_gene937	1.227e-152	494.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1IPHZ@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
HKD1_k127_4657349_1	925409.KI911562_gene936	1.267e-139	450.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1INRY@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
HKD1_k127_4665974_1	1123248.KB893322_gene589	5.945e-269	834.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
HKD1_k127_4665974_5	1123248.KB893322_gene588	7.512e-130	420.0	COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes,1IUVU@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
HKD1_k127_4665974_10	929713.NIASO_14905	2.807e-57	205.0	COG3117@1|root,COG3117@2|Bacteria,4NV8G@976|Bacteroidetes,1IU6N@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
HKD1_k127_4665974_7	1122605.KB893628_gene4428	1.948e-100	345.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4665974_6	700598.Niako_6548	3.234e-102	338.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1ISYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HKD1_k127_4665974_0	700598.Niako_6528	1.355e-281	884.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IWMA@117747|Sphingobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_4665974_4	925409.KI911562_gene1053	1.71e-136	443.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1IQDH@117747|Sphingobacteriia	976|Bacteroidetes	O	protein required for cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
HKD1_k127_4665974_8	1123248.KB893322_gene623	4.835e-88	294.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1IRYD@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD1_k127_4665974_3	700598.Niako_6515	3.768e-145	464.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IRY2@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
HKD1_k127_4665974_2	700598.Niako_6514	2.709e-192	603.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD1_k127_4665974_9	1267211.KI669560_gene721	1.103e-59	207.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,1ISNQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD1_k127_4665974_12	525373.HMPREF0766_12924	3.578e-25	109.0	2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1ITGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
HKD1_k127_4665974_11	700598.Niako_6496	6.562e-54	192.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_4667251_0	925409.KI911562_gene612	1.279e-150	481.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_4667251_3	760192.Halhy_1935	3.223e-20	91.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZFK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
HKD1_k127_4667251_2	1267211.KI669560_gene134	5.787e-53	190.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_4667251_1	925409.KI911562_gene300	3.682e-126	413.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD1_k127_4677586_3	700598.Niako_1607	8.747e-65	225.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1IYID@117747|Sphingobacteriia	976|Bacteroidetes	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD1_k127_4677586_4	1121889.AUDM01000019_gene82	2.238e-42	157.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1I2UN@117743|Flavobacteriia,2NWMH@237|Flavobacterium	976|Bacteroidetes	J	tRNA-binding protein	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
HKD1_k127_4677586_1	700598.Niako_1611	1.578e-116	381.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
HKD1_k127_4677586_5	794903.OPIT5_11735	1.257e-41	164.0	COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae	414999|Opitutae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD1_k127_4677586_6	1121895.Q765_18135	4.939e-21	96.0	COG3668@1|root,COG3668@2|Bacteria,4NX3F@976|Bacteroidetes	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HKD1_k127_4677586_2	1168289.AJKI01000002_gene2346	2.312e-96	328.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,2FM0Q@200643|Bacteroidia,3XKH3@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
HKD1_k127_4677586_0	1123248.KB893318_gene4164	6.915e-214	669.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_4716535_0	1131812.JQMS01000001_gene3230	2.801e-267	843.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	mgtB	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HKD1_k127_4716535_3	925409.KI911562_gene2513	5.471e-07	52.0	COG0484@1|root,COG0484@2|Bacteria,4NSI9@976|Bacteroidetes,1ITFJ@117747|Sphingobacteriia	976|Bacteroidetes	O	HSCB C-terminal oligomerisation domain	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
HKD1_k127_4716535_1	700598.Niako_3037	2.344e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,4NTQN@976|Bacteroidetes	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HKD1_k127_4716535_2	1089547.KB913013_gene91	2.687e-22	106.0	COG5662@1|root,COG5662@2|Bacteria,4PPG9@976|Bacteroidetes,47YMZ@768503|Cytophagia	976|Bacteroidetes	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4718361_2	929562.Emtol_3597	1.127e-106	361.0	COG4932@1|root,COG4932@2|Bacteria,4PM22@976|Bacteroidetes,47XZY@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD1_k127_4718361_3	1173020.Cha6605_3372	1.478e-20	99.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_4718361_0	1484460.JSWG01000011_gene1711	1.389e-193	618.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
HKD1_k127_4718361_1	485918.Cpin_1305	4.649e-126	408.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
HKD1_k127_4727937_2	861299.J421_1360	4.775e-76	272.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
HKD1_k127_4727937_0	761193.Runsl_1123	1.859e-216	683.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,47KKU@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_4727937_6	1216967.L100_10184	4.038e-21	102.0	COG1566@1|root,COG1566@2|Bacteria,4PKRC@976|Bacteroidetes,1IJDD@117743|Flavobacteriia,34RF7@308865|Elizabethkingia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
HKD1_k127_4727937_5	278963.ATWD01000001_gene4639	7.658e-47	173.0	COG2267@1|root,COG2267@2|Bacteria,3Y2IJ@57723|Acidobacteria,2JJ0P@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD1_k127_4727937_3	1094466.KQS_05335	2.809e-54	195.0	COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,1IJWJ@117743|Flavobacteriia,2P044@237|Flavobacterium	976|Bacteroidetes	I	Serine aminopeptidase, S33	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD1_k127_4727937_1	1443665.JACA01000022_gene5235	7.724e-107	353.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1HXQV@117743|Flavobacteriia,2YIKS@290174|Aquimarina	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD1_k127_4727937_4	760192.Halhy_4416	1.672e-48	176.0	COG2311@1|root,COG2311@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD1_k127_4730908_2	700598.Niako_4941	4.993e-105	342.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1INR8@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HKD1_k127_4730908_7	925409.KI911562_gene2825	3.906e-20	91.0	COG0690@1|root,COG0690@2|Bacteria,4PGJJ@976|Bacteroidetes,1ITUV@117747|Sphingobacteriia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HKD1_k127_4730908_0	700598.Niako_4943	5.21e-241	747.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1IPDP@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HKD1_k127_4730908_5	700598.Niako_4944	3.446e-39	147.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1ITNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
HKD1_k127_4730908_1	929713.NIASO_02780	4.717e-106	351.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD1_k127_4730908_6	485918.Cpin_1697	3.385e-26	108.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1IU0K@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD1_k127_4730908_3	1123248.KB893314_gene3627	9.339e-85	285.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1IPZJ@117747|Sphingobacteriia	976|Bacteroidetes	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HKD1_k127_4730908_4	582899.Hden_1351	1.715e-45	179.0	COG1835@1|root,COG1835@2|Bacteria,1REU1@1224|Proteobacteria,2UAM2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_4730908_8	1089547.KB913013_gene2397	5.67e-09	62.0	COG1835@1|root,COG1835@2|Bacteria,4NIR9@976|Bacteroidetes,47KQ0@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_4742531_3	700598.Niako_6196	1.159e-23	101.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD1_k127_4742531_2	880074.BARVI_08600	4.379e-41	153.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,2FT9V@200643|Bacteroidia,22YBW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD1_k127_4742531_0	700598.Niako_6197	2.022e-146	491.0	COG1752@1|root,COG1752@2|Bacteria,4NUHF@976|Bacteroidetes	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_4742531_1	1123248.KB893336_gene2849	3.167e-127	409.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HKD1_k127_4754259_9	661478.OP10G_0933	6.181e-58	205.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.3.99.16	ko:K07302,ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_4754259_2	518766.Rmar_0585	1.822e-157	522.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD1_k127_4754259_6	1122605.KB893645_gene1143	1.968e-102	344.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes	976|Bacteroidetes	S	Permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_4754259_1	929713.NIASO_00660	5.779e-179	566.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,1INPE@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
HKD1_k127_4754259_4	211114.JOEF01000001_gene7596	6.708e-106	365.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DZ3N@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_4754259_5	1123057.P872_16690	7.872e-104	345.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HKD1_k127_4754259_10	1123057.P872_16695	4.192e-51	184.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
HKD1_k127_4754259_8	929703.KE386491_gene2963	1.395e-59	211.0	COG3542@1|root,COG3542@2|Bacteria,4NPCH@976|Bacteroidetes,47PD8@768503|Cytophagia	976|Bacteroidetes	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
HKD1_k127_4754259_7	1122605.KB893637_gene3083	2.905e-79	267.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1IRSP@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HKD1_k127_4754259_0	1185876.BN8_04464	2.454e-209	657.0	28KCX@1|root,2Z9ZQ@2|Bacteria,4NJ7S@976|Bacteroidetes,47JNB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4754259_3	1123248.KB893370_gene5135	6.251e-148	471.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IX3R@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
HKD1_k127_4766053_3	700598.Niako_5473	4.368e-98	321.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
HKD1_k127_4766053_5	700598.Niako_5472	8.93e-35	139.0	COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
HKD1_k127_4766053_0	700598.Niako_5471	3.177e-270	840.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD1_k127_4766053_1	700598.Niako_5470	6.817e-217	679.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
HKD1_k127_4766053_4	925409.KI911562_gene1625	2.158e-94	316.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1ISNC@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HKD1_k127_4766053_6	700598.Niako_5468	4.558e-34	132.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
HKD1_k127_4766053_2	929713.NIASO_03105	9.882e-107	349.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD1_k127_4769746_5	388467.A19Y_0930	5.851e-39	150.0	COG3577@1|root,COG3577@2|Bacteria,1G6TW@1117|Cyanobacteria,1HCEJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
HKD1_k127_4769746_1	929713.NIASO_03020	0.0	1325.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1IQ9E@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
HKD1_k127_4769746_6	1506583.JQJY01000002_gene1534	2.959e-35	138.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia,2NWU9@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
HKD1_k127_4769746_3	1122605.KB893643_gene835	8.009e-116	379.0	2BH0I@1|root,32B0P@2|Bacteria,4P6EF@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835,DUF3658
HKD1_k127_4769746_4	1123248.KB893324_gene1746	5.124e-58	209.0	COG0457@1|root,COG0457@2|Bacteria	1123248.KB893324_gene1746|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4769746_7	485918.Cpin_3673	5.31e-32	128.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1ITHS@117747|Sphingobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_4769746_2	929713.NIASO_09500	0.0	1082.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD1_k127_4769746_0	1120968.AUBX01000016_gene1637	0.0	1446.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
HKD1_k127_4769746_8	927677.ALVU02000008_gene7	7.178e-07	51.0	COG4430@1|root,COG4430@2|Bacteria,1G2ES@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
HKD1_k127_4774770_0	929556.Solca_1447	7.36e-260	832.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1IPKR@117747|Sphingobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
HKD1_k127_4774770_2	1454007.JAUG01000018_gene1549	1.834e-13	76.0	2EUHG@1|root,33MZM@2|Bacteria,4NZ9U@976|Bacteroidetes,1IZZA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4774770_1	926556.Echvi_3096	2.404e-67	235.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,47X8T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_4777365_3	984262.SGRA_0852	6.127e-06	58.0	COG2353@1|root,COG2885@1|root,COG2353@2|Bacteria,COG2885@2|Bacteria,4NFM6@976|Bacteroidetes,1IWVQ@117747|Sphingobacteriia	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD1_k127_4777365_1	1123248.KB893328_gene894	3.856e-36	141.0	COG2204@1|root,COG2204@2|Bacteria,4NVS2@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD1_k127_4777365_0	1121481.AUAS01000005_gene2122	6.684e-123	396.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,47KEE@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
HKD1_k127_4777365_2	485913.Krac_9564	1.248e-26	117.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
HKD1_k127_4782050_2	421072.IO89_07365	3.4e-55	197.0	COG1957@1|root,COG1957@2|Bacteria,4NJ4J@976|Bacteroidetes,1I7DQ@117743|Flavobacteriia,3HIRK@358033|Chryseobacterium	976|Bacteroidetes	F	Twin-arginine translocation pathway signal protein	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
HKD1_k127_4782050_3	700598.Niako_3659	4.174e-44	162.0	COG3254@1|root,COG3254@2|Bacteria,4NSEM@976|Bacteroidetes,1ISVY@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the anomeric conversion of L-rhamnose	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
HKD1_k127_4782050_0	926549.KI421517_gene1657	1.18e-227	710.0	COG4952@1|root,COG4952@2|Bacteria,4NFWW@976|Bacteroidetes,47KMM@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	-
HKD1_k127_4782050_1	700598.Niako_3657	4.531e-134	437.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes,1IPDX@117747|Sphingobacteriia	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HKD1_k127_4782604_2	1123248.KB893316_gene4525	2.529e-51	184.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1ITBQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
HKD1_k127_4782604_1	700598.Niako_0291	9.877e-108	355.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IXA3@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
HKD1_k127_4782604_0	925409.KI911562_gene63	8.269e-241	754.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD1_k127_478411_7	1122225.AULQ01000001_gene1842	9.597e-09	63.0	COG3212@1|root,COG3212@2|Bacteria,4PNJS@976|Bacteroidetes,1IK7I@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
HKD1_k127_478411_3	1122605.KB893648_gene3650	2.974e-67	237.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_478411_0	471854.Dfer_0149	1.587e-103	377.0	COG2972@1|root,COG3292@1|root,COG3605@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,COG3605@2|Bacteria,4NHMQ@976|Bacteroidetes,47P3A@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,His_kinase,Reg_prop,Y_Y_Y
HKD1_k127_478411_5	700598.Niako_6218	6.547e-16	83.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD1_k127_478411_4	391603.FBALC1_11242	2.413e-29	124.0	2E3HM@1|root,32YG7@2|Bacteria,4NW2A@976|Bacteroidetes,1I5PX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_478411_2	929556.Solca_3838	1.055e-71	249.0	COG2114@1|root,COG2207@1|root,COG2114@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_6,GAF,Guanylate_cyc,HDOD,HTH_18,PAS_4,PAS_9
HKD1_k127_478411_1	296591.Bpro_3193	2.246e-77	273.0	COG2909@1|root,COG2909@2|Bacteria,1PXC4@1224|Proteobacteria,2W18D@28216|Betaproteobacteria	28216|Betaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
HKD1_k127_4787102_1	1408813.AYMG01000023_gene2141	8.214e-50	194.0	COG3210@1|root,COG3266@1|root,COG4675@1|root,COG4733@1|root,COG5295@1|root,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4675@2|Bacteria,COG4733@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Collagen,DUF4347,YadA_stalk
HKD1_k127_4787102_2	1137281.D778_01758	0.0005224	49.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4787102_0	1267211.KI669560_gene2871	0.0	1055.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD1_k127_4787634_7	1122605.KB893632_gene4337	0.0004293	44.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1ITU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
HKD1_k127_4787634_4	1123248.KB893386_gene1865	1.58e-34	138.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1ITG8@117747|Sphingobacteriia	976|Bacteroidetes	O	F plasmid transfer operon protein	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_4787634_5	555500.I215_14044	2.144e-21	95.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_4787634_0	1313301.AUGC01000013_gene1267	7.877e-171	544.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD1_k127_4787634_3	468059.AUHA01000003_gene1540	1.069e-36	144.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1IUMY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DsrE DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
HKD1_k127_4787634_2	1123248.KB893386_gene1950	4.222e-81	276.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,1IX7M@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4787634_1	925409.KI911562_gene2678	3.09e-119	392.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD1_k127_4787634_6	1216967.L100_09019	5.208e-11	62.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,34RDS@308865|Elizabethkingia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HKD1_k127_4795285_4	700598.Niako_0568	4.632e-36	140.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1IT7E@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
HKD1_k127_4795285_2	1123248.KB893314_gene3480	2.346e-109	360.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
HKD1_k127_4795285_0	700598.Niako_0570	2.26e-283	913.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_4795285_1	1492737.FEM08_26830	2.989e-166	526.0	COG0388@1|root,COG0388@2|Bacteria,4NGWX@976|Bacteroidetes,1I00B@117743|Flavobacteriia,2NUDR@237|Flavobacterium	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
HKD1_k127_4795285_3	991.IW20_21765	8.43e-52	185.0	2BB2W@1|root,324J1@2|Bacteria,4NQTD@976|Bacteroidetes,1I3SW@117743|Flavobacteriia,2NVZD@237|Flavobacterium	976|Bacteroidetes	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
HKD1_k127_4801387_1	700598.Niako_2059	7.652e-22	108.0	28UQV@1|root,2ZGV6@2|Bacteria,4NXW3@976|Bacteroidetes,1IZU5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4801387_0	700598.Niako_2061	2.037e-219	684.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD1_k127_4805484_7	1267211.KI669560_gene2655	7.037e-07	50.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD1_k127_4805484_2	700598.Niako_0180	2.961e-89	299.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IST6@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HKD1_k127_4805484_1	929713.NIASO_03220	8.689e-90	298.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1IP9T@117747|Sphingobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD1_k127_4805484_6	1123248.KB893326_gene1525	7.227e-40	152.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes,1IT2A@117747|Sphingobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_4805484_4	1123248.KB893326_gene1526	6.468e-71	270.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1IPY8@117747|Sphingobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
HKD1_k127_4805484_5	1123248.KB893326_gene1524	5.728e-52	192.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
HKD1_k127_4805484_0	700598.Niako_0183	1.157e-119	386.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
HKD1_k127_4805484_3	700598.Niako_0184	6.68e-74	252.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IV4C@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
HKD1_k127_481687_11	1123248.KB893314_gene3446	3.018e-09	58.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
HKD1_k127_481687_4	929713.NIASO_05600	2.217e-135	436.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydroxypyruvate isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
HKD1_k127_481687_2	925409.KI911562_gene1598	1.054e-190	601.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,1J0SK@117747|Sphingobacteriia	976|Bacteroidetes	G	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
HKD1_k127_481687_5	1380600.AUYN01000009_gene1882	5.353e-135	441.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1HYBZ@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Major facilitator superfamily MFS-1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_481687_3	485918.Cpin_7280	2.642e-187	591.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1IREZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_481687_7	1123035.ARLA01000025_gene1277	2.62e-46	169.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,1I3DZ@117743|Flavobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
HKD1_k127_481687_1	700598.Niako_6258	8.46e-218	677.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia	976|Bacteroidetes	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
HKD1_k127_481687_8	1267211.KI669560_gene259	4.517e-39	153.0	COG4654@1|root,COG4654@2|Bacteria,4NSJC@976|Bacteroidetes,1ITX4@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
HKD1_k127_481687_6	468059.AUHA01000004_gene2189	5.319e-97	323.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1IS4K@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
HKD1_k127_481687_10	1117314.PCIT_11319	1.281e-16	85.0	29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria,2Q34Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
HKD1_k127_481687_0	925409.KI911562_gene2238	2.575e-243	759.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
HKD1_k127_481687_9	925409.KI911562_gene2239	4.377e-35	134.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD1_k127_4820952_0	700598.Niako_7335	5.657e-319	984.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD1_k127_4820952_1	1122605.KB893630_gene4052	3.846e-110	389.0	28MEF@1|root,2ZAS2@2|Bacteria,4NINI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4821900_1	929556.Solca_1546	1.719e-95	352.0	COG3209@1|root,COG3209@2|Bacteria,4NHYT@976|Bacteroidetes,1ISP2@117747|Sphingobacteriia	976|Bacteroidetes	M	TIGRFAM YD repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4821900_2	1123057.P872_10960	2.749e-35	141.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	gpx1	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD1_k127_4821900_0	925409.KI911562_gene2290	1.421e-228	749.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1IRXE@117747|Sphingobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4826638_2	485918.Cpin_6889	1.152e-57	203.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD1_k127_4826638_0	929713.NIASO_11015	1.317e-115	376.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4826638_3	1123248.KB893359_gene2118	2.476e-28	117.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HKD1_k127_4826638_1	1123248.KB893330_gene390	1.05e-104	342.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1INYI@117747|Sphingobacteriia	976|Bacteroidetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD1_k127_4844727_3	909663.KI867150_gene2904	1.484e-08	57.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,2MQ5U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
HKD1_k127_4844727_2	1121875.KB907550_gene769	6.148e-57	202.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
HKD1_k127_4844727_0	1237149.C900_00331	4.895e-178	569.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,47MZ6@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
HKD1_k127_4844727_1	1237149.C900_00330	1.011e-68	236.0	COG1335@1|root,COG1335@2|Bacteria,4NKPP@976|Bacteroidetes,47PIR@768503|Cytophagia	976|Bacteroidetes	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
HKD1_k127_4881733_1	485918.Cpin_0510	1.041e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1J0KP@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_4881733_0	760192.Halhy_2327	1.689e-287	894.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_4881733_2	573413.Spirs_1160	2.79e-26	113.0	COG0454@1|root,COG0456@2|Bacteria,2JB1N@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_4896900_3	700598.Niako_5607	2.687e-72	248.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1ISDW@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
HKD1_k127_4896900_1	929713.NIASO_00950	6.39e-121	392.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1IPWN@117747|Sphingobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD1_k127_4896900_2	929713.NIASO_00945	5.056e-101	333.0	COG0740@1|root,COG0740@2|Bacteria,4NF77@976|Bacteroidetes,1J09A@117747|Sphingobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD1_k127_4896900_0	700598.Niako_6972	7.268e-205	642.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD1_k127_4911606_0	1122605.KB893629_gene4094	0.0	1103.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HKD1_k127_4911606_2	929713.NIASO_11140	7.712e-23	106.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,1IU3T@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane chaperone Skp	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD1_k127_4911606_1	700598.Niako_4929	7.639e-61	212.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_4915288_2	700598.Niako_6864	2.57e-34	135.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
HKD1_k127_4915288_0	1123248.KB893314_gene3606	5.057e-131	422.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
HKD1_k127_4915288_1	925409.KI911562_gene1175	2.068e-44	166.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1IZAC@117747|Sphingobacteriia	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
HKD1_k127_4915288_3	761193.Runsl_1749	1.866e-28	116.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
HKD1_k127_4915288_4	1123248.KB893386_gene1984	5.255e-20	89.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD1_k127_4918124_0	1122605.KB893644_gene1231	4.9e-169	557.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1IPP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD1_k127_4918124_1	700598.Niako_2008	4.45e-102	336.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
HKD1_k127_4932347_1	700598.Niako_5277	9.806e-159	509.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HKD1_k127_4932347_0	760192.Halhy_5408	8.44e-215	685.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
HKD1_k127_4932347_2	700598.Niako_5275	3.115e-138	445.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD1_k127_4932347_3	929713.NIASO_11795	6.099e-54	191.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1J0J7@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HKD1_k127_4969861_2	880074.BARVI_08600	3.082e-41	154.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,2FT9V@200643|Bacteroidia,22YBW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD1_k127_4969861_0	700598.Niako_6196	0.0	1069.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
HKD1_k127_4969861_1	1122605.KB893628_gene4485	1.688e-144	467.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD1_k127_4972544_2	1122605.KB893644_gene1412	1.18e-167	531.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD1_k127_4972544_1	1123248.KB893314_gene3395	2.642e-203	636.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
HKD1_k127_4972544_0	1267211.KI669560_gene956	1.768e-226	704.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD1_k127_4980188_5	700598.Niako_1209	2.586e-39	147.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IPUP@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
HKD1_k127_4980188_3	926549.KI421517_gene2087	7.059e-63	221.0	COG1309@1|root,COG1309@2|Bacteria,4NPAQ@976|Bacteroidetes,47PW1@768503|Cytophagia	976|Bacteroidetes	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
HKD1_k127_4980188_2	700598.Niako_5117	8.031e-146	472.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1INQ5@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
HKD1_k127_4980188_0	929713.NIASO_00810	0.0	1474.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPY3@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD1_k127_4980188_1	471854.Dfer_2175	7.68e-172	551.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,47MKH@768503|Cytophagia	976|Bacteroidetes	MU	RND efflux system, outer membrane lipoprotein, NodT	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_4980188_4	700598.Niako_6085	8.826e-48	173.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,OMP_b-brl,OMP_b-brl_2,OmpA
HKD1_k127_5016161_0	925409.KI911562_gene1393	1.08e-193	611.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
HKD1_k127_5016161_1	485918.Cpin_1464	9.629e-128	416.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IR61@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD1_k127_50312_1	929713.NIASO_09605	9.102e-108	353.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD1_k127_50312_3	1197477.IA57_07685	0.0002333	53.0	COG3266@1|root,COG3266@2|Bacteria,4NS11@976|Bacteroidetes,1I3BP@117743|Flavobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_50312_2	929556.Solca_1731	7.433e-24	106.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1ITUD@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
HKD1_k127_50312_0	925409.KI911562_gene2036	2.775e-175	552.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_503738_1	1122605.KB893625_gene2276	3.719e-136	441.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1IP9Q@117747|Sphingobacteriia	976|Bacteroidetes	H	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HKD1_k127_503738_0	700598.Niako_0512	1.326e-158	508.0	COG5000@1|root,COG5000@2|Bacteria,4PKJN@976|Bacteroidetes,1IQ9K@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_5052091_2	1454007.JAUG01000047_gene524	3.716e-134	430.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1IQ6C@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C
HKD1_k127_5052091_0	760192.Halhy_3755	0.0	1124.0	COG1434@1|root,COG1434@2|Bacteria,4NE96@976|Bacteroidetes,1IQHX@117747|Sphingobacteriia	976|Bacteroidetes	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
HKD1_k127_5052091_1	1086011.HJ01_01469	3.288e-158	506.0	COG3119@1|root,COG3119@2|Bacteria,4NF21@976|Bacteroidetes,1HZ1G@117743|Flavobacteriia,2NVDT@237|Flavobacterium	976|Bacteroidetes	P	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
HKD1_k127_5052091_4	1492737.FEM08_30540	2.145e-126	407.0	COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,1HXF7@117743|Flavobacteriia,2NV1A@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	ko:K18333	ko00051,ko01120,map00051,map01120	-	R08926	RC00066	ko00000,ko00001	-	-	-	adh_short_C2
HKD1_k127_5052091_3	700598.Niako_6702	1.154e-132	428.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,1IVQ0@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
HKD1_k127_5052091_5	700598.Niako_6703	1.708e-30	121.0	COG3254@1|root,COG3254@2|Bacteria,4NQAA@976|Bacteroidetes,1ISWR@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
HKD1_k127_5061048_0	1122605.KB893644_gene1313	8.116e-258	805.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,1IP8J@117747|Sphingobacteriia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD1_k127_5074031_2	700598.Niako_5021	4.023e-08	61.0	COG3678@1|root,COG3678@2|Bacteria,4PA3G@976|Bacteroidetes,1IUMB@117747|Sphingobacteriia	976|Bacteroidetes	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5074031_0	468059.AUHA01000004_gene2106	1.857e-62	218.0	COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,1ISWS@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase, gnat family	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD1_k127_5079686_5	1131812.JQMS01000001_gene628	0.00085	45.0	29BPY@1|root,2ZYNA@2|Bacteria,4P7KH@976|Bacteroidetes,1IB0T@117743|Flavobacteriia,2NZJP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5079686_2	1165841.SULAR_02578	9.123e-66	231.0	28K10@1|root,2Z9QW@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
HKD1_k127_5079686_3	1123057.P872_07690	3.711e-39	153.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,47XX2@768503|Cytophagia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_5079686_0	153721.MYP_3118	1.938e-184	587.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,47KI3@768503|Cytophagia	976|Bacteroidetes	V	PFAM Multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HKD1_k127_5079686_1	700598.Niako_6235	1.598e-109	364.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1IU84@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_5079686_4	700598.Niako_6236	1.467e-11	69.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD1_k127_5080555_0	1250278.JQNQ01000001_gene430	7.579e-36	149.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,1HXTG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
HKD1_k127_5080555_1	1166018.FAES_1116	1.385e-21	100.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,47PV1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
HKD1_k127_5089535_2	929713.NIASO_11605	9.384e-94	313.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
HKD1_k127_5089535_0	929713.NIASO_11600	1.279e-194	618.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD1_k127_5089535_1	700598.Niako_7075	2.438e-96	321.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD1_k127_5090642_2	1267211.KI669560_gene1544	0.0001746	44.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_5090642_0	313606.M23134_01996	3.501e-120	398.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_5090642_1	700598.Niako_3733	1.979e-62	222.0	COG0300@1|root,COG0300@2|Bacteria,4NK81@976|Bacteroidetes,1ISB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_5092171_1	714943.Mucpa_6668	7.915e-52	187.0	COG1522@1|root,COG1522@2|Bacteria,4NMPD@976|Bacteroidetes,1ISU0@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD1_k127_5092171_0	1123248.KB893337_gene2427	5.963e-112	369.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1IPGU@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_5092171_2	1121920.AUAU01000005_gene976	5.319e-33	131.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5092171_3	1237149.C900_04034	1.181e-28	117.0	COG2329@1|root,COG2329@2|Bacteria,4NUCI@976|Bacteroidetes	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5093771_0	588596.U9UMD6	4.264e-105	349.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HKD1_k127_5093771_1	700598.Niako_2452	2.619e-104	346.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1INWN@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD1_k127_5097655_4	1150600.ADIARSV_0117	7.787e-117	380.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
HKD1_k127_5097655_9	1267211.KI669560_gene110	2.92e-49	177.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1ITK5@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HKD1_k127_5097655_6	1189619.pgond44_08812	1.242e-73	253.0	COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes,1IJMZ@117743|Flavobacteriia,4C483@83612|Psychroflexus	976|Bacteroidetes	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS
HKD1_k127_5097655_7	929703.KE386491_gene582	9.075e-63	226.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,47KBM@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
HKD1_k127_5097655_1	700598.Niako_6413	1.946e-198	624.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_5097655_8	929713.NIASO_15415	2.133e-53	190.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,1IYB6@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
HKD1_k127_5097655_0	700598.Niako_6407	0.0	1261.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
HKD1_k127_5097655_2	1267211.KI669560_gene663	1.418e-178	565.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD1_k127_5097655_5	1122605.KB893635_gene3501	3.619e-111	363.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
HKD1_k127_5097655_3	1123277.KB893174_gene6054	8.807e-133	428.0	COG2313@1|root,COG2313@2|Bacteria,4NKE0@976|Bacteroidetes,47UFW@768503|Cytophagia	976|Bacteroidetes	Q	Indigoidine synthase A like protein	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
HKD1_k127_5106955_2	700598.Niako_5774	4.646e-65	226.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD1_k127_5106955_1	700598.Niako_5775	2.78e-145	481.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_5106955_0	1122605.KB893646_gene128	0.0	1632.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD1_k127_5106955_3	929556.Solca_2130	2.911e-13	72.0	COG4899@1|root,COG4899@2|Bacteria,4NNKE@976|Bacteroidetes,1IXDZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
HKD1_k127_5106955_4	313595.P700755_000330	0.0005809	42.0	COG1943@1|root,COG1943@2|Bacteria,4NTG8@976|Bacteroidetes,1I47T@117743|Flavobacteriia	976|Bacteroidetes	L	SPTR Genome sequencing data, contig C243	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
HKD1_k127_5108677_4	700598.Niako_0140	8.242e-41	153.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD1_k127_5108677_0	925409.KI911562_gene44	0.0	1211.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
HKD1_k127_5108677_5	925409.KI911562_gene93	4.583e-40	149.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1ITH1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
HKD1_k127_5108677_1	700598.Niako_5478	8.579e-107	349.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
HKD1_k127_5108677_2	700598.Niako_5477	1.032e-78	267.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
HKD1_k127_5108677_3	929713.NIASO_11015	3.389e-51	183.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5111716_0	1223410.KN050846_gene2836	8.776e-275	882.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
HKD1_k127_5111716_5	1189619.pgond44_14078	1.811e-126	424.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GAF_2,HATPase_c,HisKA
HKD1_k127_5111716_3	1123248.KB893350_gene2906	7.018e-142	474.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD1_k127_5111716_2	1123248.KB893352_gene1783	9.763e-147	488.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD1_k127_5111716_1	925409.KI911562_gene2744	2.186e-165	549.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
HKD1_k127_5111716_4	1123248.KB893350_gene2907	5.189e-136	456.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1IVE0@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
HKD1_k127_5125011_8	1123248.KB893326_gene1539	1.74e-38	149.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1J0SU@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD1_k127_5125011_6	700598.Niako_2840	1.471e-125	408.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NKCH@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_5125011_1	700598.Niako_2839	6.023e-261	810.0	COG1070@1|root,COG1070@2|Bacteria,4NFBG@976|Bacteroidetes,1IPCF@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HKD1_k127_5125011_5	700598.Niako_2838	1.163e-161	512.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1IP7I@117747|Sphingobacteriia	976|Bacteroidetes	M	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
HKD1_k127_5125011_0	1123248.KB893318_gene4100	6.664e-277	856.0	COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,1IPDK@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
HKD1_k127_5125011_3	1123248.KB893326_gene1536	2.428e-168	535.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1IP75@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
HKD1_k127_5125011_4	1123248.KB893326_gene1535	1.602e-167	530.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1IR2I@117747|Sphingobacteriia	976|Bacteroidetes	H	SPTR Demethylmenaquinone methyltransferase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
HKD1_k127_5125011_2	700598.Niako_2834	1.139e-239	744.0	COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,1IPCK@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
HKD1_k127_5125011_7	1121904.ARBP01000060_gene1918	7.372e-59	207.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47JGE@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_5125848_0	700598.Niako_0117	1.819e-206	649.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HKD1_k127_5125848_2	925409.KI911562_gene1520	1.778e-35	143.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes	976|Bacteroidetes	I	Pfam PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_5125848_1	760192.Halhy_3780	3.389e-57	207.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
HKD1_k127_5127457_4	1270196.JCKI01000001_gene4106	4.129e-12	77.0	2EERZ@1|root,338JN@2|Bacteria,4NTN7@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1735)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,DUF4361
HKD1_k127_5127457_5	1033732.CAHI01000035_gene2794	5.717e-05	55.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD1_k127_5127457_2	700598.Niako_0176	3.127e-51	183.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
HKD1_k127_5127457_3	1454007.JAUG01000010_gene2514	3.253e-39	149.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1IYIE@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_5127457_1	1123248.KB893314_gene3570	2.453e-94	314.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD1_k127_5127457_0	925409.KI911562_gene74	3.174e-167	530.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1INUM@117747|Sphingobacteriia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD1_k127_5132915_0	700598.Niako_1209	2.356e-219	687.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IPUP@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
HKD1_k127_5132915_1	1123248.KB893321_gene484	4.658e-32	126.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPDG@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD1_k127_5139357_2	172045.KS04_15780	5.991e-48	179.0	COG0457@1|root,COG0457@2|Bacteria,4PKS0@976|Bacteroidetes,1IMN6@117743|Flavobacteriia,34QEA@308865|Elizabethkingia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5139357_1	700598.Niako_6909	9.956e-269	846.0	COG1629@1|root,COG4771@2|Bacteria,4PKRZ@976|Bacteroidetes,1J0Q2@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5139357_0	1122605.KB893626_gene2355	4.339e-293	904.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD1_k127_5156864_2	700598.Niako_5689	4.503e-86	286.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD1_k127_5156864_1	925409.KI911562_gene428	2.583e-145	467.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD1_k127_5156864_0	929713.NIASO_17605	9.922e-215	670.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1IQUC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_5157953_3	700598.Niako_2572	1.373e-13	71.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
HKD1_k127_5157953_1	401053.AciPR4_1932	2.048e-104	354.0	28J1S@1|root,2Z8G5@2|Bacteria,3Y4PE@57723|Acidobacteria,2JJCK@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Deoxyribonuclease II	-	-	-	-	-	-	-	-	-	-	-	-	DNase_II
HKD1_k127_5157953_0	1041159.AZUW01000006_gene1889	3.963e-211	696.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
HKD1_k127_5157953_2	345341.KUTG_03126	2.296e-79	277.0	COG3369@1|root,COG3369@2|Bacteria,2GK8Q@201174|Actinobacteria,4E016@85010|Pseudonocardiales	201174|Actinobacteria	S	Ferritin-like	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin-like,zf-CDGSH
HKD1_k127_5161124_1	1123248.KB893327_gene796	1.427e-75	281.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_5161124_0	1123248.KB893327_gene795	1.422e-75	259.0	COG2197@1|root,COG2197@2|Bacteria,4NNEU@976|Bacteroidetes,1J05I@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_5163632_0	745718.JADT01000008_gene3115	7.343e-132	436.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5163632_1	1121957.ATVL01000013_gene18	3.513e-78	278.0	COG3193@1|root,COG3193@2|Bacteria,4NGRH@976|Bacteroidetes,47Q7C@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
HKD1_k127_5163632_2	484018.BACPLE_03621	0.000455	49.0	2EKZ0@1|root,33ENH@2|Bacteria,4NZEE@976|Bacteroidetes,2FSUA@200643|Bacteroidia,4AQWT@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4984)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4843,DUF4984
HKD1_k127_5176971_6	700598.Niako_6301	2.98e-39	152.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1ISSQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5176971_0	700598.Niako_6302	2.401e-287	890.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD1_k127_5176971_4	700598.Niako_6303	7.312e-57	201.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,1ITGU@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD1_k127_5176971_3	700598.Niako_6304	1.305e-80	273.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
HKD1_k127_5176971_7	700598.Niako_6305	1.963e-31	129.0	2DNMN@1|root,32Y54@2|Bacteria,4NW3V@976|Bacteroidetes,1IYIN@117747|Sphingobacteriia	976|Bacteroidetes	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
HKD1_k127_5176971_5	700598.Niako_6250	6.94e-53	190.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD1_k127_5176971_2	1123248.KB893331_gene3779	1.005e-98	328.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1ISMY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl hydrolases family 25	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
HKD1_k127_5176971_1	1267211.KI669560_gene471	5.211e-168	543.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_5176971_8	1123248.KB893370_gene4990	5.942e-22	98.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
HKD1_k127_5176971_10	1469607.KK073768_gene3693	3.188e-05	47.0	COG1181@1|root,COG2940@1|root,COG1181@2|Bacteria,COG2940@2|Bacteria,1G3G5@1117|Cyanobacteria,1HQAK@1161|Nostocales	1117|Cyanobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
HKD1_k127_5177721_1	1123248.KB893381_gene1074	1.37e-68	238.0	COG1555@1|root,COG1555@2|Bacteria,4NUGB@976|Bacteroidetes,1J0F4@117747|Sphingobacteriia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5177721_0	1123248.KB893381_gene1073	5.932e-220	701.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1INMF@117747|Sphingobacteriia	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
HKD1_k127_5188467_0	1123248.KB893330_gene449	2.167e-207	653.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_5188467_1	509635.N824_07185	3.546e-121	406.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,Sulfate_transp
HKD1_k127_5188467_2	1123248.KB893318_gene4213	1.381e-62	216.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
HKD1_k127_5191734_0	929713.NIASO_00840	0.0	1232.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD1_k127_519365_4	700598.Niako_0900	2.104e-54	202.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_519365_0	1123248.KB893330_gene411	0.0	1107.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD1_k127_519365_3	1123248.KB893330_gene410	6.557e-78	262.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_519365_2	1408813.AYMG01000008_gene4035	4.884e-103	345.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IQ2G@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_519365_1	714943.Mucpa_4573	2.674e-168	537.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
HKD1_k127_519365_5	468059.AUHA01000003_gene1550	1.56e-15	84.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
HKD1_k127_5212551_2	760192.Halhy_1898	1.271e-33	137.0	COG3350@1|root,COG3350@2|Bacteria,4PK14@976|Bacteroidetes,1IZ1G@117747|Sphingobacteriia	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5212551_3	1219072.VHA01S_058_00260	4.408e-31	136.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S846@1236|Gammaproteobacteria,1XY38@135623|Vibrionales	135623|Vibrionales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
HKD1_k127_5212551_4	312309.VF_A0625	1.054e-25	119.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S846@1236|Gammaproteobacteria,1XY38@135623|Vibrionales	135623|Vibrionales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
HKD1_k127_5212551_1	1185876.BN8_02798	9.032e-40	153.0	COG3193@1|root,COG3193@2|Bacteria,4NP80@976|Bacteroidetes,47SA6@768503|Cytophagia	976|Bacteroidetes	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
HKD1_k127_5212551_0	504472.Slin_2519	4.633e-126	415.0	COG3386@1|root,COG3386@2|Bacteria,4NS13@976|Bacteroidetes,47UF3@768503|Cytophagia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
HKD1_k127_5213726_0	925409.KI911562_gene1477	0.0	1448.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1IQY4@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
HKD1_k127_5225572_0	700598.Niako_7056	1.502e-148	476.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1IW4I@117747|Sphingobacteriia	976|Bacteroidetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD1_k127_5225572_3	700598.Niako_7057	5.317e-66	228.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1IYAU@117747|Sphingobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HKD1_k127_5225572_4	1122605.KB893644_gene1423	2.941e-30	130.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1IPHJ@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD1_k127_5225572_1	929713.NIASO_11680	1.489e-101	339.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,1IRT8@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD1_k127_5225572_2	700598.Niako_7060	7.119e-90	316.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia	976|Bacteroidetes	NU	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
HKD1_k127_5227510_2	1185876.BN8_03246	1.101e-25	111.0	COG0463@1|root,COG0463@2|Bacteria,4NGWW@976|Bacteroidetes,47P65@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5227510_1	118163.Ple7327_3829	1.226e-60	222.0	COG0500@1|root,COG0500@2|Bacteria,1GQU0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD1_k127_5227510_0	313606.M23134_07914	3.396e-90	302.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47KDC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5229650_0	700598.Niako_0949	5.384e-90	303.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,1IQSZ@117747|Sphingobacteriia	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD1_k127_5229650_1	1249975.JQLP01000005_gene2523	3.153e-49	183.0	2CHBZ@1|root,349GY@2|Bacteria,4P65U@976|Bacteroidetes,1IA5D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5229650_2	929713.NIASO_20990	3.476e-13	71.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
HKD1_k127_5235151_2	1121286.AUMT01000001_gene169	2.691e-38	154.0	COG4733@1|root,COG4886@1|root,COG4733@2|Bacteria,COG4886@2|Bacteria,4PN99@976|Bacteroidetes,1IK1Q@117743|Flavobacteriia,3ZUQM@59732|Chryseobacterium	976|Bacteroidetes	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5235151_3	1121957.ATVL01000006_gene2766	1.182e-22	115.0	COG3291@1|root,COG3291@2|Bacteria,4NJHV@976|Bacteroidetes,47R0V@768503|Cytophagia	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HKD1_k127_5235151_0	1048983.EL17_09785	7.79e-91	336.0	COG2133@1|root,COG2133@2|Bacteria,4NH6T@976|Bacteroidetes,47NWE@768503|Cytophagia	976|Bacteroidetes	CG	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
HKD1_k127_5235151_4	471854.Dfer_0718	3.561e-22	114.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
HKD1_k127_5235151_1	1123248.KB893325_gene1149	1.891e-90	303.0	COG0412@1|root,COG0412@2|Bacteria,4NIXW@976|Bacteroidetes,1IXE7@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,Pec_lyase,Peptidase_S9
HKD1_k127_5243173_5	1123248.KB893331_gene3796	0.0003683	45.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HKD1_k127_5243173_0	1185876.BN8_04997	0.0	1264.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HKD1_k127_5243173_3	700598.Niako_0126	1.075e-59	218.0	COG2067@1|root,COG2067@2|Bacteria,4PJ15@976|Bacteroidetes,1IXNX@117747|Sphingobacteriia	976|Bacteroidetes	I	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_5243173_4	1267211.KI669560_gene1273	6.198e-49	179.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1IY4K@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
HKD1_k127_5243173_2	1123248.KB893370_gene5019	8.742e-149	475.0	COG5285@1|root,COG5285@2|Bacteria,4NJ09@976|Bacteroidetes,1IQAS@117747|Sphingobacteriia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
HKD1_k127_5243173_1	700598.Niako_0128	2.056e-204	642.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD1_k127_5244527_9	485918.Cpin_0366	4.961e-40	154.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_5244527_0	1185876.BN8_03110	0.0	1305.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
HKD1_k127_5244527_5	700598.Niako_2567	4.168e-104	349.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
HKD1_k127_5244527_2	700598.Niako_2566	2.545e-178	565.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1IQSA@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
HKD1_k127_5244527_1	700598.Niako_2565	9.831e-209	653.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
HKD1_k127_5244527_4	1122605.KB893627_gene2982	1.129e-137	450.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD1_k127_5244527_8	700598.Niako_4522	3.078e-55	200.0	COG1073@1|root,COG1073@2|Bacteria,4NFVJ@976|Bacteroidetes,1J0PC@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
HKD1_k127_5244527_3	443143.GM18_1819	3.538e-145	467.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HKD1_k127_5244527_7	1121129.KB903368_gene800	1.062e-83	286.0	COG0599@1|root,COG0599@2|Bacteria,4NH7X@976|Bacteroidetes,2G2QM@200643|Bacteroidia,22WBI@171551|Porphyromonadaceae	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	ABM,CMD,Cupin_2
HKD1_k127_5244527_6	435591.BDI_1568	1.525e-98	327.0	COG1917@1|root,COG2220@1|root,COG1917@2|Bacteria,COG2220@2|Bacteria,4P6GJ@976|Bacteroidetes,2FY09@200643|Bacteroidia	976|Bacteroidetes	S	ARD/ARD' family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_5244923_2	468059.AUHA01000002_gene563	5.35e-165	527.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_5244923_0	925409.KI911562_gene2430	0.0	1170.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
HKD1_k127_5244923_5	700598.Niako_1176	5.537e-54	192.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HKD1_k127_5244923_4	1122605.KB893627_gene2962	3.081e-65	244.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,1IPFV@117747|Sphingobacteriia	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HKD1_k127_5244923_3	700598.Niako_3186	1.035e-148	477.0	COG0226@1|root,COG0226@2|Bacteria,4PKPM@976|Bacteroidetes,1J0SY@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD1_k127_5244923_1	700598.Niako_5176	4.814e-262	832.0	COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
HKD1_k127_5250546_0	1123277.KB893172_gene538	1.066e-260	814.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_5261243_2	746697.Aeqsu_2761	2.733e-20	94.0	COG1674@1|root,COG1674@2|Bacteria,4PMA8@976|Bacteroidetes,1I6B6@117743|Flavobacteriia	976|Bacteroidetes	D	ftsk spoiiie	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5261243_0	221288.JH992901_gene5748	2.744e-61	243.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
HKD1_k127_5261243_1	468059.AUHA01000002_gene563	3.235e-45	186.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_52659_0	1434325.AZQN01000001_gene596	7.01e-206	666.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD1_k127_52659_1	700598.Niako_0400	1.844e-182	576.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HKD1_k127_5267795_0	748247.AZKH_1956	2.887e-241	750.0	COG5361@1|root,COG5361@2|Bacteria,1PJY5@1224|Proteobacteria,2W9FE@28216|Betaproteobacteria,2KZE5@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
HKD1_k127_5267795_1	484018.BACPLE_01021	2.303e-163	523.0	COG0641@1|root,COG0641@2|Bacteria,4NG1N@976|Bacteroidetes,2FMBY@200643|Bacteroidia,4AKCJ@815|Bacteroidaceae	976|Bacteroidetes	C	COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)	atsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD1_k127_5267795_2	1267533.KB906737_gene1782	0.0003196	46.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
HKD1_k127_528523_3	700598.Niako_0905	2.142e-63	221.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1IPYC@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, deoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HKD1_k127_528523_0	925409.KI911562_gene1254	4.109e-159	511.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1IPA4@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
HKD1_k127_528523_2	509635.N824_15730	3.482e-64	225.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,1ISBH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
HKD1_k127_528523_1	700598.Niako_0949	1.763e-146	472.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,1IQSZ@117747|Sphingobacteriia	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD1_k127_5298606_5	1267534.KB906755_gene4479	1.641e-56	199.0	COG0667@1|root,COG1917@1|root,COG0667@2|Bacteria,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,DUF4437,EcsC
HKD1_k127_5298606_1	1123248.KB893316_gene4679	1.562e-147	472.0	COG2207@1|root,COG2207@2|Bacteria,4NDYY@976|Bacteroidetes,1IQRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_5298606_6	533247.CRD_01352	7.424e-23	100.0	COG2026@1|root,COG2026@2|Bacteria,1G9AD@1117|Cyanobacteria,1HPNM@1161|Nostocales	1117|Cyanobacteria	DJ	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
HKD1_k127_5298606_7	1233951.IO90_02760	6.226e-10	62.0	2BWKX@1|root,33G81@2|Bacteria,4NYKR@976|Bacteroidetes,1IB9A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
HKD1_k127_5298606_2	517418.Ctha_0791	1.415e-131	426.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_5298606_4	1131812.JQMS01000001_gene941	4.703e-68	239.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia,2NYX7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5298606_0	700598.Niako_4146	3.001e-192	607.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,1IP4F@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
HKD1_k127_5298606_3	1123248.KB893359_gene2004	1.189e-102	336.0	COG3391@1|root,COG3391@2|Bacteria,4NX00@976|Bacteroidetes,1IZG3@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
HKD1_k127_5322205_0	1048983.EL17_15560	1.1e-112	383.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
HKD1_k127_5322205_2	925409.KI911562_gene440	6.841e-65	224.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
HKD1_k127_5322205_1	1150600.ADIARSV_0117	6.657e-74	252.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
HKD1_k127_5322629_1	929713.NIASO_19815	1.457e-140	447.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1IRMY@117747|Sphingobacteriia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
HKD1_k127_5322629_4	761193.Runsl_2520	2.864e-64	226.0	COG4636@1|root,COG4636@2|Bacteria,4NNM9@976|Bacteroidetes,47Q1A@768503|Cytophagia	976|Bacteroidetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
HKD1_k127_5322629_0	929713.NIASO_19820	2.016e-178	562.0	COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1IR39@117747|Sphingobacteriia	976|Bacteroidetes	HJ	Glutathione synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5322629_2	1122605.KB893629_gene4153	4.965e-86	293.0	COG2382@1|root,COG2382@2|Bacteria,4NI86@976|Bacteroidetes,1IQ5J@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_5322629_3	1434325.AZQN01000001_gene596	7.143e-69	244.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
HKD1_k127_5330842_5	925409.KI911562_gene1601	3.336e-52	187.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1IQJ1@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	3.2.1.197	ko:K21065	-	-	R11544	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
HKD1_k127_5330842_3	700598.Niako_6656	1.591e-123	402.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1IQ87@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5330842_0	929713.NIASO_11525	3.542e-240	746.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD1_k127_5330842_6	700598.Niako_6653	3.406e-27	113.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU1T@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD1_k127_5330842_7	700598.Niako_6652	7.656e-22	96.0	2DQSK@1|root,338E4@2|Bacteria,4NX60@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5330842_4	1122605.KB893625_gene1548	1.404e-106	348.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD1_k127_5330842_1	700598.Niako_1109	1.524e-164	545.0	COG2203@1|root,COG2203@2|Bacteria,4NE84@976|Bacteroidetes,1IPG6@117747|Sphingobacteriia	976|Bacteroidetes	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5330842_2	1122605.KB893644_gene1526	9.425e-135	442.0	COG3039@1|root,COG3039@2|Bacteria,4NGW9@976|Bacteroidetes	976|Bacteroidetes	L	PFAM Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
HKD1_k127_5337123_2	509635.N824_23215	2.645e-11	63.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1IP7D@117747|Sphingobacteriia	976|Bacteroidetes	G	major facilitator superfamily	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
HKD1_k127_5337123_5	865937.Gilli_1012	1.381e-08	57.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	3.1.21.3	ko:K01154,ko:K07461	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GIY-YIG
HKD1_k127_5337123_6	313595.P700755_002548	0.0002274	44.0	COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1I2RZ@117743|Flavobacteriia,4C4DJ@83612|Psychroflexus	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD1_k127_5337123_4	194867.ALBQ01000011_gene384	7.211e-09	60.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
HKD1_k127_5337123_0	1123248.KB893386_gene1842	2.257e-231	725.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1IPCS@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
HKD1_k127_5337123_1	700598.Niako_3688	5.675e-14	74.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD1_k127_5340109_1	1122605.KB893626_gene2365	3.727e-129	415.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD1_k127_5340109_0	700598.Niako_6321	2.358e-144	473.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1ITFP@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD1_k127_5340109_2	1408813.AYMG01000025_gene2667	1.785e-31	125.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,1INWT@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD1_k127_5342059_1	700598.Niako_2184	1.775e-84	282.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD1_k127_5342059_0	929713.NIASO_02185	1.144e-95	316.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1IRGC@117747|Sphingobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD1_k127_5342059_2	1341181.FLJC2902T_27420	6.095e-36	139.0	COG2315@1|root,COG2315@2|Bacteria,4NTRF@976|Bacteroidetes,1ID1Z@117743|Flavobacteriia,2NWYS@237|Flavobacterium	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HKD1_k127_5342059_3	929713.NIASO_01355	1.33e-25	106.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD1_k127_5342059_4	929713.NIASO_01360	5.013e-18	83.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1ISA4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD1_k127_5344087_1	1185876.BN8_03828	2.421e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,4NH1Y@976|Bacteroidetes,47JW6@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	gdh3	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
HKD1_k127_5344087_0	153721.MYP_329	5.469e-120	398.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
HKD1_k127_5344087_3	1453498.LG45_06840	3.714e-50	188.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,1I3BU@117743|Flavobacteriia,2NV2W@237|Flavobacterium	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_5344087_4	290512.Paes_0922	1.753e-16	83.0	COG3118@1|root,COG3118@2|Bacteria,1FE0Z@1090|Chlorobi	1090|Chlorobi	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_5344087_2	761193.Runsl_0435	3.084e-53	191.0	COG3350@1|root,COG3350@2|Bacteria,4NR42@976|Bacteroidetes,47XU3@768503|Cytophagia	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
HKD1_k127_5354790_0	925409.KI911562_gene1450	4.804e-64	222.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD1_k127_5354790_1	485918.Cpin_0381	4.643e-47	174.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1IT1Y@117747|Sphingobacteriia	976|Bacteroidetes	O	TIGRFAM Peroxiredoxin, osmotically inducible protein C, subgroup	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
HKD1_k127_5354790_2	1300345.LF41_2983	2.447e-19	99.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
HKD1_k127_535735_0	700598.Niako_6041	1.189e-180	573.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HKD1_k127_535735_1	925409.KI911562_gene1390	9.313e-64	229.0	2F80M@1|root,340E7@2|Bacteria,4P4VX@976|Bacteroidetes,1IYG6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5367706_2	1122605.KB893628_gene4474	1.615e-116	377.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,1ITBG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD1_k127_5367706_1	700598.Niako_6566	7.042e-196	616.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1IQFF@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_5367706_4	700598.Niako_6567	2.072e-16	83.0	2DQVY@1|root,338ZT@2|Bacteria,4PJ6A@976|Bacteroidetes,1IZN9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5367706_3	700598.Niako_6569	1.075e-111	365.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1IPPM@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
HKD1_k127_5367706_0	925409.KI911562_gene503	1.255e-205	644.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1INVN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
HKD1_k127_5369345_3	1121904.ARBP01000005_gene4607	5.363e-115	382.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
HKD1_k127_5369345_1	649349.Lbys_3304	0.0	1009.0	COG0129@1|root,COG0129@2|Bacteria,4NEKY@976|Bacteroidetes,47K3U@768503|Cytophagia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
HKD1_k127_5369345_2	700598.Niako_2842	9.871e-261	810.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1IQBF@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
HKD1_k127_5369345_0	700598.Niako_2841	0.0	1405.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1J0SU@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
HKD1_k127_5372473_4	700598.Niako_2992	1.815e-42	159.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1IUIV@117747|Sphingobacteriia	976|Bacteroidetes	S	Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
HKD1_k127_5372473_2	700598.Niako_2993	1.122e-98	326.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
HKD1_k127_5372473_1	929713.NIASO_01185	3.464e-117	381.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_5372473_0	925409.KI911562_gene2165	0.0	1276.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD1_k127_5372473_3	700598.Niako_2999	2.945e-45	171.0	COG0671@1|root,COG0671@2|Bacteria,4NQ5M@976|Bacteroidetes,1J0DT@117747|Sphingobacteriia	976|Bacteroidetes	I	SMART Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD1_k127_5385072_2	338966.Ppro_1421	1.925e-46	181.0	COG0438@1|root,COG0438@2|Bacteria,1PFC7@1224|Proteobacteria,439Z9@68525|delta/epsilon subdivisions,2WWVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_5385072_1	749222.Nitsa_1996	3.598e-60	218.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,42WPQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2,RgpF
HKD1_k127_5385072_0	1267211.KI669560_gene1650	5.114e-231	742.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1IP87@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD1_k127_5388499_0	1122605.KB893644_gene1399	1.032e-95	319.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1IWHU@117747|Sphingobacteriia	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD1_k127_5388499_2	700598.Niako_5621	2.918e-71	252.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5388499_1	700598.Niako_5622	8.887e-78	265.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5391851_1	1538644.KO02_04085	6.835e-18	83.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_5391851_0	1123277.KB893172_gene538	9.727e-211	664.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_5396322_3	1123248.KB893348_gene204	4.053e-27	122.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1ITGA@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_5396322_2	700598.Niako_6584	3.732e-103	339.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1IQZH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
HKD1_k127_5396322_0	929713.NIASO_13335	1.268e-240	748.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD1_k127_5396322_1	865937.Gilli_0451	3.222e-128	422.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1I02U@117743|Flavobacteriia,2P72K@244698|Gillisia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_5396751_3	1121904.ARBP01000038_gene2569	4.932e-07	51.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
HKD1_k127_5396751_1	742727.HMPREF9447_04165	6.767e-104	350.0	COG0738@1|root,COG0738@2|Bacteria,4NHZ7@976|Bacteroidetes,2FPGQ@200643|Bacteroidia,4AMIG@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
HKD1_k127_5396751_2	485917.Phep_0679	6.584e-102	340.0	COG1940@1|root,COG1940@2|Bacteria,4NHNJ@976|Bacteroidetes,1IUUW@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD1_k127_5396751_0	468059.AUHA01000005_gene2553	5.126e-207	651.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
HKD1_k127_5405838_8	925409.KI911562_gene1277	1.371e-24	108.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,1ITC9@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
HKD1_k127_5405838_6	1121481.AUAS01000014_gene2450	5.974e-42	160.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD1_k127_5405838_9	925409.KI911562_gene1708	1.805e-23	104.0	2C1KT@1|root,33DVE@2|Bacteria,4NY76@976|Bacteroidetes,1IUF1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5405838_5	700598.Niako_4307	1.257e-43	163.0	COG2217@1|root,COG2217@2|Bacteria,4NYQS@976|Bacteroidetes,1IUK1@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5405838_4	743722.Sph21_0290	9.625e-58	207.0	COG0845@1|root,COG0845@2|Bacteria,4NHFQ@976|Bacteroidetes,1IY3Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
HKD1_k127_5405838_1	1121288.AULL01000012_gene476	1.188e-243	756.0	COG3696@1|root,COG3696@2|Bacteria,4NFD2@976|Bacteroidetes,1I1AN@117743|Flavobacteriia,3ZRC7@59732|Chryseobacterium	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD1_k127_5405838_0	700598.Niako_6212	0.0	1078.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IP0C@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
HKD1_k127_5405838_7	525373.HMPREF0766_14158	4.127e-32	126.0	COG0053@1|root,COG0053@2|Bacteria,4NVGY@976|Bacteroidetes,1ITV5@117747|Sphingobacteriia	976|Bacteroidetes	P	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	MerC
HKD1_k127_5405838_2	925409.KI911562_gene1713	3.475e-200	632.0	COG1538@1|root,COG1538@2|Bacteria,4NFEC@976|Bacteroidetes,1ISNJ@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_5405838_3	925409.KI911562_gene1714	2.158e-67	234.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IS3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_3,HlyD_D23
HKD1_k127_5409525_2	700598.Niako_0428	2.442e-91	302.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD1_k127_5409525_3	1122605.KB893643_gene843	3.147e-69	241.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1ITW4@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
HKD1_k127_5409525_0	929713.NIASO_06145	9.995e-294	914.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD1_k127_5409525_4	1122605.KB893631_gene3883	7.998e-40	155.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mtrC	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,DUF3347,HlyD_D23
HKD1_k127_5409525_1	700598.Niako_2188	1.907e-264	826.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5410178_3	643867.Ftrac_0904	5.114e-05	50.0	COG2911@1|root,COG2911@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
HKD1_k127_5410178_0	929556.Solca_2394	1.242e-198	638.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
HKD1_k127_5410178_1	1122605.KB893625_gene2340	2.269e-33	130.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1INZY@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_5421673_3	468059.AUHA01000003_gene1550	1.459e-12	74.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
HKD1_k127_5421673_0	760192.Halhy_4416	1.763e-137	451.0	COG2311@1|root,COG2311@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
HKD1_k127_5421673_1	1123057.P872_07650	1.165e-106	352.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD1_k127_5421673_4	290397.Adeh_2288	3.38e-07	58.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4440,SnoaL_2,SnoaL_3
HKD1_k127_5421673_2	278963.ATWD01000001_gene4639	3.189e-88	299.0	COG2267@1|root,COG2267@2|Bacteria,3Y2IJ@57723|Acidobacteria,2JJ0P@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD1_k127_5422420_1	700598.Niako_5041	2.332e-178	564.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD1_k127_5422420_2	700598.Niako_5040	1.094e-29	119.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1ITAU@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HKD1_k127_5422420_0	700598.Niako_5039	2.09e-254	795.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD1_k127_5422530_0	929713.NIASO_05335	1.623e-210	662.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
HKD1_k127_5422530_2	700598.Niako_2477	5.286e-152	491.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,1J0HP@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD1_k127_5422530_1	700598.Niako_2476	3.469e-155	500.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,1J0MU@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
HKD1_k127_5424409_4	700598.Niako_6071	1.169e-21	94.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD1_k127_5424409_3	929713.NIASO_14940	3.833e-61	216.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
HKD1_k127_5424409_2	700598.Niako_6069	2.446e-94	318.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1IS2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HKD1_k127_5424409_1	929713.NIASO_14950	7.75e-115	381.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD1_k127_5424409_0	929713.NIASO_14955	8.464e-259	804.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1INZ2@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
HKD1_k127_5427047_6	929713.NIASO_01850	6.798e-33	132.0	COG3631@1|root,COG3631@2|Bacteria,4NPEK@976|Bacteroidetes	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
HKD1_k127_5427047_7	1296416.JACB01000010_gene1575	2.312e-29	119.0	COG2169@1|root,COG2169@2|Bacteria,4NV90@976|Bacteroidetes,1I5VR@117743|Flavobacteriia,2YK0V@290174|Aquimarina	976|Bacteroidetes	F	Metal binding domain of Ada	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
HKD1_k127_5427047_3	620914.JH621298_gene3446	1.627e-68	242.0	COG0596@1|root,COG0596@2|Bacteria,4NN9S@976|Bacteroidetes,1I4NH@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HKD1_k127_5427047_1	714943.Mucpa_3016	1.507e-126	410.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,1IP7V@117747|Sphingobacteriia	976|Bacteroidetes	K	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
HKD1_k127_5427047_5	643867.Ftrac_1066	2.061e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,47QTI@768503|Cytophagia	976|Bacteroidetes	G	mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_5427047_0	1237149.C900_04255	6.213e-138	447.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47N5F@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HKD1_k127_5427047_4	700598.Niako_6307	3.701e-51	186.0	COG3832@1|root,COG3832@2|Bacteria,4PAUN@976|Bacteroidetes,1IYZG@117747|Sphingobacteriia	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HKD1_k127_5427047_2	929713.NIASO_14435	2.303e-112	364.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1IQ4T@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
HKD1_k127_5435845_0	929713.NIASO_17660	4.289e-254	796.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_5435845_5	1122605.KB893626_gene2663	3.246e-55	196.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1ISV5@117747|Sphingobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD1_k127_5435845_2	929713.NIASO_17670	1.752e-132	434.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
HKD1_k127_5435845_1	925409.KI911562_gene1454	3.769e-181	576.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD1_k127_5435845_3	700598.Niako_5697	2.654e-124	402.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1ISXM@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_5435845_4	700598.Niako_5698	8.299e-101	332.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1ITSA@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD1_k127_5440036_0	925409.KI911562_gene1430	3.151e-163	516.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_5440036_2	1341181.FLJC2902T_18320	2.065e-10	65.0	2FI3I@1|root,349WB@2|Bacteria,4P6BE@976|Bacteroidetes,1IAPJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5440036_3	1219049.SP5_032_00130	8.862e-08	60.0	COG3637@1|root,COG3637@2|Bacteria,1PW82@1224|Proteobacteria,2U8GW@28211|Alphaproteobacteria,2K6DC@204457|Sphingomonadales	204457|Sphingomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5440036_4	267608.RSc0609	5.287e-05	50.0	28KDQ@1|root,2ZAX1@2|Bacteria,1QY70@1224|Proteobacteria,2WHCH@28216|Betaproteobacteria,1KGBB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5440036_1	755732.Fluta_2853	2.754e-93	313.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PBBW@246874|Cryomorphaceae	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
HKD1_k127_5460865_1	925409.KI911562_gene3006	1.593e-100	338.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD1_k127_5460865_0	700598.Niako_5110	1.634e-158	508.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD1_k127_5460865_3	925409.KI911562_gene3008	7.216e-45	164.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1ISVJ@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HKD1_k127_5460865_2	700598.Niako_5112	7.384e-96	320.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
HKD1_k127_5460865_5	929713.NIASO_18885	5.113e-07	51.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,PorP_SprF
HKD1_k127_5466313_2	700598.Niako_3685	1.368e-32	129.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1IXQD@117747|Sphingobacteriia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD1_k127_5466313_0	925409.KI911562_gene1683	7.567e-200	626.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD1_k127_5466313_1	700598.Niako_3678	1.459e-67	240.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiA
HKD1_k127_546721_0	700598.Niako_5815	4.368e-254	797.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HKD1_k127_546721_1	1123248.KB893317_gene4354	2.002e-128	423.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1IXEP@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD1_k127_546721_3	700598.Niako_0996	2.95e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1IXKQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_546721_2	1227739.Hsw_2756	1.768e-105	356.0	COG1538@1|root,COG1538@2|Bacteria,4NHEA@976|Bacteroidetes,47MAJ@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
HKD1_k127_546721_4	925409.KI911562_gene2310	1.244e-33	134.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IQXT@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
HKD1_k127_5472087_0	1122605.KB893646_gene152	1.962e-317	981.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD1_k127_5472087_2	1267533.KB906740_gene137	7.797e-11	67.0	29Y1S@1|root,30JUQ@2|Bacteria,3Y90C@57723|Acidobacteria,2JNWN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5472087_1	1267211.KI669560_gene521	1.441e-102	338.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,1ISPG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
HKD1_k127_5472988_17	700598.Niako_0416	3.202e-19	88.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD1_k127_5472988_16	929713.NIASO_09615	1.801e-33	132.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HKD1_k127_5472988_14	1267211.KI669560_gene1564	7.433e-47	175.0	2FEUI@1|root,346TG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5472988_10	700598.Niako_0422	1.993e-69	238.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1ISJ9@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HKD1_k127_5472988_0	1267211.KI669560_gene1566	2.558e-284	880.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HKD1_k127_5472988_7	700598.Niako_1893	1.805e-103	344.0	COG0589@1|root,COG0589@2|Bacteria,4NI7R@976|Bacteroidetes,1INVG@117747|Sphingobacteriia	976|Bacteroidetes	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HKD1_k127_5472988_2	1123248.KB893316_gene4610	2.788e-152	487.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD1_k127_5472988_5	700598.Niako_3669	2.171e-116	386.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HKD1_k127_5472988_8	1123248.KB893359_gene2203	3.582e-90	301.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1IW0G@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
HKD1_k127_5472988_9	1123248.KB893316_gene4612	1.485e-80	273.0	COG1073@1|root,COG1073@2|Bacteria,4NMFG@976|Bacteroidetes,1IV84@117747|Sphingobacteriia	976|Bacteroidetes	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HKD1_k127_5472988_12	468059.AUHA01000003_gene1730	1.476e-63	223.0	COG3685@1|root,COG3685@2|Bacteria,4P08F@976|Bacteroidetes,1IV02@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
HKD1_k127_5472988_1	1123248.KB893316_gene4614	4.919e-240	747.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1IV2U@117747|Sphingobacteriia	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
HKD1_k127_5472988_11	1123248.KB893316_gene4616	5.283e-64	224.0	COG1881@1|root,COG1881@2|Bacteria,4NH14@976|Bacteroidetes,1IT2Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Raf kinase inhibitor-like protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
HKD1_k127_5472988_4	1086011.HJ01_03172	2.992e-117	396.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia,2NWFB@237|Flavobacterium	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD1_k127_5472988_3	700598.Niako_1885	2.543e-118	384.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1IPKD@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
HKD1_k127_5472988_6	700598.Niako_1886	1.473e-111	365.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
HKD1_k127_5472988_13	700598.Niako_1887	1.21e-57	206.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1IRW5@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
HKD1_k127_5487995_4	1123248.KB893325_gene1149	4.167e-120	388.0	COG0412@1|root,COG0412@2|Bacteria,4NIXW@976|Bacteroidetes,1IXE7@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,Pec_lyase,Peptidase_S9
HKD1_k127_5487995_9	700598.Niako_6878	7.689e-06	53.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1ITXJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5487995_5	700598.Niako_6880	2.706e-101	331.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1IQKN@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_5487995_1	1122605.KB893647_gene447	1.176e-177	561.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD1_k127_5487995_0	700598.Niako_6884	8.406e-182	576.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD1_k127_5487995_3	1450525.JATV01000005_gene462	8.725e-123	409.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1I0VI@117743|Flavobacteriia,2NSWG@237|Flavobacterium	976|Bacteroidetes	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
HKD1_k127_5487995_6	700598.Niako_6887	5.683e-99	326.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
HKD1_k127_5487995_2	700598.Niako_6888	3.336e-131	432.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,1IVNH@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
HKD1_k127_5487995_7	929713.NIASO_09835	2.719e-71	246.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
HKD1_k127_5490860_2	1123248.KB893326_gene1521	3.576e-147	491.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1IQBI@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
HKD1_k127_5490860_4	925409.KI911562_gene2743	4.192e-56	198.0	COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1ISWK@117747|Sphingobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD1_k127_5490860_1	1121875.KB907550_gene641	4.766e-158	505.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia	976|Bacteroidetes	T	Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
HKD1_k127_5490860_0	700598.Niako_1610	7.069e-265	820.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_5490860_3	700598.Niako_2625	1.865e-72	247.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD1_k127_5495287_8	925409.KI911562_gene1836	2.123e-19	91.0	COG4748@1|root,COG4748@2|Bacteria,4PN76@976|Bacteroidetes,1J0M4@117747|Sphingobacteriia	976|Bacteroidetes	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
HKD1_k127_5495287_3	1267211.KI669560_gene2367	4.163e-145	462.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_5495287_0	700598.Niako_5057	3.766e-320	1021.0	COG3735@1|root,COG3735@2|Bacteria,4NGNW@976|Bacteroidetes,1IS2W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM GumN	-	-	-	-	-	-	-	-	-	-	-	-	TraB
HKD1_k127_5495287_2	700598.Niako_5056	4.704e-211	657.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1INNG@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD1_k127_5495287_4	1492738.FEM21_30000	6.542e-83	286.0	COG1305@1|root,COG1305@2|Bacteria,4NKZ4@976|Bacteroidetes,1HZU5@117743|Flavobacteriia,2NSZP@237|Flavobacterium	976|Bacteroidetes	E	transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HKD1_k127_5495287_5	700598.Niako_5063	7.272e-51	189.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
HKD1_k127_5495287_1	700598.Niako_5065	6.851e-279	864.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
HKD1_k127_5495287_6	700598.Niako_5066	1.648e-47	179.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
HKD1_k127_5502049_4	1123248.KB893320_gene3831	1.041e-174	552.0	COG0642@1|root,COG2205@2|Bacteria,4NEZM@976|Bacteroidetes,1INUP@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
HKD1_k127_5502049_5	700598.Niako_0111	7.665e-138	446.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD1_k127_5502049_6	1123248.KB893320_gene3829	4.518e-84	282.0	COG2156@1|root,COG2156@2|Bacteria,4NMME@976|Bacteroidetes	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
HKD1_k127_5502049_0	1123248.KB893337_gene2326	0.0	1101.0	COG2216@1|root,COG2216@2|Bacteria,4NFBI@976|Bacteroidetes,1IP79@117747|Sphingobacteriia	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
HKD1_k127_5502049_1	1123248.KB893320_gene3827	3.974e-320	985.0	COG2060@1|root,COG2060@2|Bacteria,4NF2G@976|Bacteroidetes,1IQRZ@117747|Sphingobacteriia	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
HKD1_k127_5502049_3	762903.Pedsa_1581	1.09e-188	598.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IQ1A@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
HKD1_k127_5502049_2	925409.KI911562_gene318	1.815e-245	766.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia	976|Bacteroidetes	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
HKD1_k127_5502049_7	700598.Niako_6660	5.513e-29	118.0	2DQR8@1|root,33877@2|Bacteria,4NWHC@976|Bacteroidetes,1IUJD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5508584_2	700598.Niako_6678	1.306e-87	296.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
HKD1_k127_5508584_0	929562.Emtol_1697	0.0	1082.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD1_k127_5508584_1	925409.KI911562_gene414	5.827e-222	697.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD1_k127_5508584_4	929713.NIASO_17615	1.435e-33	132.0	COG0640@1|root,COG0640@2|Bacteria,4NSQD@976|Bacteroidetes	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD1_k127_5508584_3	700598.Niako_6674	1.94e-60	215.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
HKD1_k127_5510896_0	1270193.JARP01000001_gene2358	1.371e-119	396.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia,2NTT8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HKD1_k127_5510896_2	1267534.KB906758_gene2483	5.176e-54	195.0	COG2318@1|root,COG2318@2|Bacteria,3Y51S@57723|Acidobacteria,2JJG3@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_5510896_1	700598.Niako_7231	2.728e-83	280.0	COG3279@1|root,COG3279@2|Bacteria,4NP17@976|Bacteroidetes	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_5511518_0	700598.Niako_0356	3.073e-194	612.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1IQIH@117747|Sphingobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD1_k127_5511518_1	700598.Niako_1014	1.449e-175	559.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD1_k127_5511518_3	153721.MYP_3568	2.799e-23	104.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47RM9@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
HKD1_k127_5511518_2	762903.Pedsa_0443	4.511e-47	170.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1IQE3@117747|Sphingobacteriia	976|Bacteroidetes	G	sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HKD1_k127_5512788_0	1267211.KI669560_gene398	3.331e-312	966.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVD8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_5512788_2	694427.Palpr_1921	2.077e-76	263.0	COG0726@1|root,COG0726@2|Bacteria,4NRNQ@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5512788_1	661478.OP10G_0632	1.359e-127	415.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
HKD1_k127_5512788_4	694427.Palpr_1921	0.0001425	47.0	COG0726@1|root,COG0726@2|Bacteria,4NRNQ@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5512788_3	487521.OCU_41440	6.245e-06	49.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria,2348T@1762|Mycobacteriaceae	201174|Actinobacteria	M	Phosphoesterase family	sapM	GO:0003674,GO:0003824,GO:0003993,GO:0004438,GO:0004805,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006742,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009117,GO:0009166,GO:0009987,GO:0016310,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019203,GO:0019362,GO:0019364,GO:0019438,GO:0019439,GO:0019637,GO:0030258,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046486,GO:0046488,GO:0046496,GO:0046700,GO:0046834,GO:0046854,GO:0050189,GO:0050192,GO:0051186,GO:0051187,GO:0052744,GO:0052866,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072526,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
HKD1_k127_5512868_2	929713.NIASO_00270	3.881e-74	252.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1ISQ4@117747|Sphingobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD1_k127_5512868_1	700598.Niako_5540	2.796e-88	292.0	COG1978@1|root,COG1978@2|Bacteria,4NNSE@976|Bacteroidetes,1IS2T@117747|Sphingobacteriia	976|Bacteroidetes	S	Ribonuclease H-like	-	-	-	ko:K09776	-	-	-	-	ko00000	-	-	-	RNaseH_like
HKD1_k127_5512868_0	700598.Niako_5539	1.134e-134	446.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	5_nucleotid_C,HemolysinCabind,Laminin_G_3,VCBS
HKD1_k127_5512868_3	700598.Niako_5537	1.669e-30	122.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1ITJY@117747|Sphingobacteriia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
HKD1_k127_5513916_0	1122605.KB893637_gene3108	6.349e-229	716.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
HKD1_k127_5513916_2	929713.NIASO_04055	7.878e-71	243.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1IS2U@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
HKD1_k127_5513916_1	1121889.AUDM01000015_gene2037	2.991e-140	466.0	COG1629@1|root,COG1629@2|Bacteria,4PM72@976|Bacteroidetes,1IKBT@117743|Flavobacteriia	976|Bacteroidetes	P	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4139,DUF4140,Plug
HKD1_k127_5519448_0	700598.Niako_4523	2.903e-268	828.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD1_k127_5519448_2	700598.Niako_4519	6.178e-43	163.0	2EDN0@1|root,337HT@2|Bacteria,4NVQJ@976|Bacteroidetes,1ITXS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5519448_1	700598.Niako_4518	8.23e-79	267.0	COG1595@1|root,COG1595@2|Bacteria,4NP02@976|Bacteroidetes,1J06I@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_5519448_4	700598.Niako_4517	1.97e-24	106.0	2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes,1IU65@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5519448_3	1123248.KB893370_gene5078	1.434e-39	152.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD1_k127_5523991_3	929562.Emtol_1189	2.984e-100	337.0	COG3659@1|root,COG3659@2|Bacteria,4NHN1@976|Bacteroidetes,47MFC@768503|Cytophagia	976|Bacteroidetes	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K16080	-	-	-	-	ko00000,ko02000	1.B.4.2.2	-	-	OprB
HKD1_k127_5523991_1	700598.Niako_7341	1.967e-148	475.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD1_k127_5523991_0	760192.Halhy_0235	1.849e-213	676.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1IWIB@117747|Sphingobacteriia	976|Bacteroidetes	F	Formate--tetrahydrofolate ligase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HKD1_k127_5523991_2	700598.Niako_7340	1.365e-102	336.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IRG0@117747|Sphingobacteriia	976|Bacteroidetes	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD1_k127_5544211_5	1122176.KB903531_gene3069	1.772e-60	214.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1IV4P@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG1523 Type II secretory pathway pullulanase PulA and related glycosidase	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD1_k127_5544211_0	760192.Halhy_3325	4.475e-225	703.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1J19G@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HKD1_k127_5544211_7	1123248.KB893318_gene4163	2.709e-06	52.0	2CD33@1|root,2ZCU1@2|Bacteria,4P6XT@976|Bacteroidetes,1IZH0@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5544211_2	1239962.C943_04519	1.079e-166	539.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47KU0@768503|Cytophagia	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
HKD1_k127_5544211_6	1150600.ADIARSV_0205	2.937e-26	111.0	COG0724@1|root,COG0724@2|Bacteria,4NUIS@976|Bacteroidetes,1ITB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
HKD1_k127_5544211_1	700598.Niako_1810	2.059e-172	554.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1IR01@117747|Sphingobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HKD1_k127_5544211_3	929713.NIASO_05330	3.889e-116	388.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_5544211_4	925409.KI911562_gene2428	3.075e-107	351.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1IV68@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
HKD1_k127_5557344_4	762903.Pedsa_0237	3.193e-69	241.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes	976|Bacteroidetes	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
HKD1_k127_5557344_1	1122605.KB893647_gene288	6.816e-116	381.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1IQMJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
HKD1_k127_5557344_0	700598.Niako_6984	0.0	1558.0	COG1629@1|root,COG1629@2|Bacteria,4PKRD@976|Bacteroidetes,1IP4U@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5557344_3	1123248.KB893385_gene4799	6.362e-86	293.0	COG2067@1|root,COG2067@2|Bacteria,4NN8Q@976|Bacteroidetes,1ITBK@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
HKD1_k127_5557344_5	1123277.KB893243_gene253	5.716e-62	218.0	COG2128@1|root,COG2128@2|Bacteria,4P1UG@976|Bacteroidetes	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5557344_2	485918.Cpin_3955	2.508e-110	361.0	COG1028@1|root,COG1028@2|Bacteria,4P0BZ@976|Bacteroidetes	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD1_k127_556975_0	700598.Niako_7214	4.623e-170	537.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
HKD1_k127_556975_3	700598.Niako_7213	4.264e-56	200.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,1ISCW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD1_k127_556975_2	700598.Niako_7212	6.487e-93	308.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD1_k127_556975_4	700598.Niako_7211	4.866e-44	162.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD1_k127_556975_1	1122605.KB893626_gene2602	8.228e-100	330.0	COG1018@1|root,COG1018@2|Bacteria,4PN6Y@976|Bacteroidetes,1IXDV@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523,ko:K05784	ko00362,ko00364,ko00520,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00520,map00622,map01100,map01120,map01220	M00551	R03391,R03392,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00230,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
HKD1_k127_5569964_0	1123248.KB893381_gene1078	2.318e-310	968.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
HKD1_k127_5569964_1	925409.KI911562_gene1388	8.743e-34	133.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD1_k127_5578132_3	1500281.JQKZ01000008_gene2527	5.082e-41	155.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia,3ZQJQ@59732|Chryseobacterium	976|Bacteroidetes	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
HKD1_k127_5578132_0	755732.Fluta_0844	2.885e-138	458.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
HKD1_k127_5578132_4	1123248.KB893326_gene1347	1.231e-29	122.0	COG1917@1|root,COG1917@2|Bacteria,4NW55@976|Bacteroidetes,1IY7S@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5578132_1	1341181.FLJC2902T_13620	8.75e-125	410.0	COG1565@1|root,COG1565@2|Bacteria,4PD08@976|Bacteroidetes,1IDI8@117743|Flavobacteriia,2NYHP@237|Flavobacterium	976|Bacteroidetes	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
HKD1_k127_5578132_2	485918.Cpin_6617	2.566e-102	338.0	COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1INY4@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	cysI	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr,TusA
HKD1_k127_5579087_1	1517682.HW49_11350	1.487e-48	175.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,22WZC@171551|Porphyromonadaceae	976|Bacteroidetes	E	Glutamate formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
HKD1_k127_5579087_2	700598.Niako_5600	2.298e-46	175.0	COG0741@1|root,COG0741@2|Bacteria,4NEKW@976|Bacteroidetes,1IRNH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HKD1_k127_5579087_0	1380391.JIAS01000020_gene1540	2.625e-121	411.0	COG1502@1|root,COG1502@2|Bacteria,1R4EZ@1224|Proteobacteria,2U0UJ@28211|Alphaproteobacteria,2JXF7@204441|Rhodospirillales	204441|Rhodospirillales	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
HKD1_k127_5583493_3	1144313.PMI10_03624	8.299e-73	252.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia,2NTVH@237|Flavobacterium	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_5583493_2	525257.HMPREF0204_14592	2.577e-81	278.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia,3ZPW7@59732|Chryseobacterium	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5583493_0	1239962.C943_01832	4.233e-243	758.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
HKD1_k127_5583493_5	1123248.KB893370_gene5041	6.394e-25	106.0	COG0607@1|root,COG0607@2|Bacteria,4NUN5@976|Bacteroidetes,1J07C@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_5583493_7	926549.KI421517_gene443	2.479e-21	98.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_5583493_1	468059.AUHA01000005_gene2438	3.392e-138	453.0	COG3203@1|root,COG3203@2|Bacteria,4PMSP@976|Bacteroidetes	976|Bacteroidetes	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
HKD1_k127_5583493_4	755732.Fluta_3524	3.851e-41	154.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2PC1E@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_5583493_6	755732.Fluta_2866	1.682e-21	96.0	2ABGN@1|root,310XN@2|Bacteria,4PFJR@976|Bacteroidetes,1I767@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5584756_2	700598.Niako_7064	8.199e-54	191.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1ISEW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
HKD1_k127_5584756_0	1122605.KB893644_gene1405	8.533e-114	368.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
HKD1_k127_5584756_1	929713.NIASO_11670	4.459e-56	199.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
HKD1_k127_5592650_0	391596.PBAL39_16114	1.347e-292	904.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD1_k127_5592816_2	1434325.AZQN01000004_gene1904	6.85e-11	72.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Gram_pos_anchor,LTD,SLH
HKD1_k127_5592816_1	1122605.KB893625_gene1797	5.787e-101	333.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1IRY5@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD1_k127_5592816_0	925409.KI911562_gene2239	7.229e-126	406.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD1_k127_5593729_2	1267211.KI669560_gene525	1.177e-31	124.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD1_k127_5593729_3	1169144.KB910926_gene1165	4.003e-18	87.0	COG0477@1|root,COG2814@2|Bacteria,1VDCK@1239|Firmicutes,4HMPX@91061|Bacilli,1ZR8G@1386|Bacillus	91061|Bacilli	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
HKD1_k127_5593729_4	762903.Pedsa_0155	4.492e-14	78.0	2ECT8@1|root,336QU@2|Bacteria,4NW1U@976|Bacteroidetes,1ITVE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5593729_0	929713.NIASO_17370	0.0	1068.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPMK@117747|Sphingobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD1_k127_5593729_1	1237149.C900_03633	3.037e-42	160.0	COG2162@1|root,COG2162@2|Bacteria,4NPEY@976|Bacteroidetes,47QTB@768503|Cytophagia	976|Bacteroidetes	Q	Belongs to the arylamine N-acetyltransferase family	nat	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
HKD1_k127_5609896_1	925409.KI911562_gene1114	4.828e-152	488.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1IPQQ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
HKD1_k127_5609896_6	925409.KI911562_gene1115	3.91e-57	203.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes	976|Bacteroidetes	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
HKD1_k127_5609896_4	700598.Niako_6727	9.412e-79	267.0	COG1514@1|root,COG1514@2|Bacteria,4NX5U@976|Bacteroidetes,1IYZ5@117747|Sphingobacteriia	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD1_k127_5609896_0	1122605.KB893625_gene2108	1.264e-195	615.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD1_k127_5609896_3	1041930.Mtc_0418	2.14e-106	357.0	arCOG08191@1|root,arCOG08191@2157|Archaea,2Y14D@28890|Euryarchaeota,2NADQ@224756|Methanomicrobia	224756|Methanomicrobia	L	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5609896_2	421531.IX38_21745	1.364e-120	390.0	COG4422@1|root,COG4422@2|Bacteria,4NJKJ@976|Bacteroidetes,1I0JM@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
HKD1_k127_5609896_5	1122605.KB893647_gene398	1.873e-74	253.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IQFR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
HKD1_k127_5626270_4	1094466.KQS_12840	8.09e-18	83.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia,2NWE8@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD1_k127_5626270_1	700598.Niako_5640	1.346e-111	364.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD1_k127_5626270_0	1122605.KB893646_gene180	3.743e-231	719.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD1_k127_5626270_2	929713.NIASO_16900	6.366e-39	145.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1ITA3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD1_k127_5626270_3	700598.Niako_5643	1.874e-35	136.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD1_k127_5627410_0	700598.Niako_2016	3.932e-143	462.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD1_k127_5627410_2	929713.NIASO_04635	1.622e-64	223.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
HKD1_k127_5627410_3	1123248.KB893348_gene240	2.604e-48	180.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1IRPU@117747|Sphingobacteriia	976|Bacteroidetes	E	SPTR Transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
HKD1_k127_5627410_1	1123248.KB893348_gene240	1.912e-110	372.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1IRPU@117747|Sphingobacteriia	976|Bacteroidetes	E	SPTR Transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
HKD1_k127_5627410_4	700598.Niako_2014	3.287e-22	98.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1ITG6@117747|Sphingobacteriia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
HKD1_k127_5645484_2	1123248.KB893320_gene3888	4.971e-18	87.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
HKD1_k127_5645484_1	929556.Solca_1448	5.825e-45	174.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1IRZU@117747|Sphingobacteriia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
HKD1_k127_5645484_0	504472.Slin_2813	1.349e-92	319.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_564736_6	761193.Runsl_5621	2.673e-92	312.0	COG0151@1|root,COG0151@2|Bacteria,4P144@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_564736_9	929713.NIASO_11025	1.659e-11	71.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1IWIT@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
HKD1_k127_564736_4	1267211.KI669560_gene916	1.215e-103	341.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1IR1N@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD1_k127_564736_2	1267211.KI669560_gene915	9.347e-116	383.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1J0PK@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
HKD1_k127_564736_0	1267211.KI669560_gene464	2.078e-160	519.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
HKD1_k127_564736_8	700598.Niako_7006	5.207e-85	286.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1IS50@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD1_k127_564736_5	1123248.KB893315_gene3132	7.928e-96	319.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
HKD1_k127_564736_7	700598.Niako_7004	2.373e-86	291.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD1_k127_564736_3	700598.Niako_5688	1.026e-111	366.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_564736_1	700598.Niako_5689	9.976e-117	378.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD1_k127_5660463_1	700598.Niako_2038	1.213e-34	150.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1IXAB@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,His_kinase,TPR_10,TPR_12,TPR_7,TPR_8
HKD1_k127_5660463_0	700598.Niako_5447	8.208e-55	201.0	COG5429@1|root,COG5429@2|Bacteria,4NNGV@976|Bacteroidetes,1ISAC@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
HKD1_k127_5660463_3	373994.Riv7116_3706	1.651e-06	56.0	COG4276@1|root,COG4276@2|Bacteria,1GK2Z@1117|Cyanobacteria,1HT5S@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5660463_2	700598.Niako_5039	3.085e-13	70.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HKD1_k127_5667494_1	1123248.KB893385_gene4734	7.452e-37	143.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_5667494_0	1239962.C943_04282	2.858e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_5667494_2	1121904.ARBP01000013_gene354	2.477e-10	63.0	COG3292@1|root,COG4219@1|root,COG3292@2|Bacteria,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HKD1_k127_570480_0	1123248.KB893317_gene4292	1.076e-236	738.0	COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_570480_2	1121373.KB903629_gene373	2.585e-127	413.0	COG0265@1|root,COG0265@2|Bacteria,4NFAJ@976|Bacteroidetes,47N2H@768503|Cytophagia	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
HKD1_k127_570480_3	504472.Slin_1436	2.611e-42	162.0	COG1309@1|root,COG1309@2|Bacteria,4NKWP@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_570480_1	1237149.C900_00550	5.408e-164	540.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47K79@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CBM9_1,Glyco_hydro_20,Glyco_hydro_20b,Glycohydro_20b2
HKD1_k127_570480_4	509191.AEDB02000003_gene1037	9.523e-18	91.0	COG4447@1|root,COG4447@2|Bacteria,1VCI4@1239|Firmicutes,24CF6@186801|Clostridia,3WPEC@541000|Ruminococcaceae	186801|Clostridia	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,N_methyl
HKD1_k127_5705339_5	313612.L8106_26632	1.267e-24	108.0	COG2340@1|root,COG2340@2|Bacteria,1G6I4@1117|Cyanobacteria,1HBFT@1150|Oscillatoriales	1117|Cyanobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
HKD1_k127_5705339_2	1122605.KB893643_gene850	2.37e-40	153.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD1_k127_5705339_1	388413.ALPR1_10585	1.96e-43	160.0	COG4357@1|root,COG4357@2|Bacteria,4NRI3@976|Bacteroidetes,47UMK@768503|Cytophagia	976|Bacteroidetes	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
HKD1_k127_5705339_3	925409.KI911562_gene1315	6.553e-29	128.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
HKD1_k127_5705339_0	700598.Niako_2639	4.913e-117	379.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD1_k127_5705339_4	742726.HMPREF9448_00670	9.624e-25	109.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
HKD1_k127_5723033_2	929713.NIASO_00940	4.152e-97	319.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD1_k127_5723033_1	1121898.Q766_05010	1.226e-145	467.0	COG2730@1|root,COG2730@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2NU0X@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	eglS	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
HKD1_k127_5723033_0	153721.MYP_2588	3.513e-266	835.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47KIX@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD1_k127_5724112_3	509635.N824_11000	1.235e-53	193.0	COG0521@1|root,COG0521@2|Bacteria,4NEQZ@976|Bacteroidetes,1J06W@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
HKD1_k127_5724112_2	929556.Solca_3703	2.446e-64	226.0	2CTRP@1|root,33412@2|Bacteria,4PC9A@976|Bacteroidetes,1IYGK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011
HKD1_k127_5724112_6	1408310.JHUW01000007_gene356	1.172e-35	141.0	2E4GG@1|root,32ZBN@2|Bacteria,4NW9P@976|Bacteroidetes,2FSEX@200643|Bacteroidia	976|Bacteroidetes	S	Lipid-binding putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipid_bd
HKD1_k127_5724112_9	1123035.ARLA01000019_gene2683	5.329e-06	52.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OMP_b-brl,OmpA_like
HKD1_k127_5724112_1	760117.JN27_22600	9.625e-88	299.0	2DVZY@1|root,33XWI@2|Bacteria	2|Bacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HKD1_k127_5724112_8	883078.HMPREF9695_02218	4.799e-30	124.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,3JY5J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	MA20_36205	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
HKD1_k127_5724112_5	1189612.A33Q_1478	1.248e-40	165.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,47XFM@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_5724112_4	1189612.A33Q_1478	1.736e-46	184.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,47XFM@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_5724112_0	1408813.AYMG01000029_gene4710	8.387e-96	317.0	2EIZG@1|root,33CQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5724112_7	1121897.AUGO01000005_gene145	5.823e-31	138.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,2NSB2@237|Flavobacterium	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_5729167_5	1123248.KB893381_gene1058	5.85e-05	47.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
HKD1_k127_5729167_2	234267.Acid_5630	1.3e-41	164.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD1_k127_5729167_1	926562.Oweho_2124	8.121e-59	207.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2PBRB@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
HKD1_k127_5729167_0	558152.IQ37_11810	1.45e-66	231.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,1I8KU@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_5729167_4	926556.Echvi_1232	1.356e-09	59.0	COG3070@1|root,COG3070@2|Bacteria,4NTQF@976|Bacteroidetes	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
HKD1_k127_5746790_3	1123248.KB893370_gene5008	3.75e-24	102.0	COG0412@1|root,COG0412@2|Bacteria,4NKMA@976|Bacteroidetes,1IQ0X@117747|Sphingobacteriia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
HKD1_k127_5746790_2	1227739.Hsw_0520	3.255e-37	163.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_5746790_1	391587.KAOT1_20302	6.897e-46	173.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1HXC7@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_5746790_4	376686.Fjoh_1311	9.995e-05	54.0	COG3637@1|root,COG3637@2|Bacteria,4NN1G@976|Bacteroidetes,1IIEJ@117743|Flavobacteriia,2NUUV@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_5746790_0	925409.KI911562_gene543	8.561e-48	177.0	28HPC@1|root,2Z7XD@2|Bacteria,4NYNG@976|Bacteroidetes,1IYND@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
HKD1_k127_5768345_4	1454007.JAUG01000085_gene3261	5.843e-27	112.0	2AE6H@1|root,2ZYG3@2|Bacteria,4NPIR@976|Bacteroidetes,1J14P@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5768345_1	700598.Niako_4446	1.656e-188	597.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD1_k127_5768345_2	929713.NIASO_19715	1.283e-64	226.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1ISC5@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphoesterase PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD1_k127_5768345_0	1122605.KB893634_gene4197	5.304e-261	819.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD1_k127_5768345_3	700598.Niako_4442	1.158e-43	163.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_5772482_10	700598.Niako_5154	2.725e-56	200.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,4NP35@976|Bacteroidetes,1IVW7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
HKD1_k127_5772482_1	700598.Niako_5153	1.723e-158	508.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HKD1_k127_5772482_11	1382359.JIAL01000001_gene1449	4.503e-48	179.0	COG2068@1|root,COG2068@2|Bacteria,3Y593@57723|Acidobacteria,2JJP4@204432|Acidobacteriia	204432|Acidobacteriia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD1_k127_5772482_2	700598.Niako_0551	2.569e-153	490.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD1_k127_5772482_5	1123248.KB893314_gene3278	1.01e-124	410.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IR9R@117747|Sphingobacteriia	976|Bacteroidetes	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HKD1_k127_5772482_6	1123248.KB893314_gene3277	1.074e-111	364.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1IRF7@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5772482_8	1337936.IJ00_09660	1.229e-77	263.0	COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria,1HKRX@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HKD1_k127_5772482_12	1123248.KB893314_gene3276	1.358e-16	83.0	COG1977@1|root,COG1977@2|Bacteria,4PGWN@976|Bacteroidetes,1IUJJ@117747|Sphingobacteriia	976|Bacteroidetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD1_k127_5772482_3	1123248.KB893314_gene3275	3.304e-152	490.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HKD1_k127_5772482_9	1123248.KB893314_gene3274	2.182e-68	235.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1ITHC@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
HKD1_k127_5772482_4	700598.Niako_0555	2.632e-134	433.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1INZV@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
HKD1_k127_5772482_0	1123248.KB893314_gene3695	1.793e-214	673.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1INWM@117747|Sphingobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HKD1_k127_5772482_14	762903.Pedsa_3157	1.148e-05	48.0	2EWYR@1|root,346M6@2|Bacteria,4P5DU@976|Bacteroidetes,1IZAP@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
HKD1_k127_5772482_13	925409.KI911562_gene2881	7.417e-14	77.0	2EWYR@1|root,346M6@2|Bacteria,4P5DU@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
HKD1_k127_5772482_7	925409.KI911562_gene2464	7.806e-87	294.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,1INS6@117747|Sphingobacteriia	976|Bacteroidetes	P	Nitric oxide reductase	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
HKD1_k127_5775682_0	714943.Mucpa_0222	9.096e-176	560.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,1IRWN@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
HKD1_k127_5775682_1	929556.Solca_2689	5.384e-49	177.0	COG0726@1|root,COG0726@2|Bacteria,4NGMX@976|Bacteroidetes,1IPFM@117747|Sphingobacteriia	976|Bacteroidetes	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5788505_0	1123248.KB893337_gene2451	1.765e-113	375.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,1IY8C@117747|Sphingobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
HKD1_k127_5788505_4	1121859.KB890738_gene3335	3.329e-05	51.0	2CFVU@1|root,3373K@2|Bacteria,4NX7Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5788505_2	468059.AUHA01000003_gene1556	8.354e-102	335.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,1IX7M@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5788505_3	1237149.C900_03631	7.255e-74	251.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47XD5@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD1_k127_5788505_1	929562.Emtol_2463	1.783e-107	353.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,47PJT@768503|Cytophagia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
HKD1_k127_5793152_0	1123248.KB893315_gene3021	1.134e-101	336.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_5795052_0	1267211.KI669560_gene2535	8.999e-130	419.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD1_k127_5795052_1	929713.NIASO_10600	1.377e-98	328.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD1_k127_5796161_4	700598.Niako_5542	8.167e-94	315.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1IQ48@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
HKD1_k127_5796161_6	485918.Cpin_7095	3.394e-73	254.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1ISMS@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD1_k127_5796161_5	1121904.ARBP01000012_gene1244	8.074e-75	263.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5796161_0	700598.Niako_4534	5.025e-218	691.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1IQXH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
HKD1_k127_5796161_2	700598.Niako_5548	1.178e-184	595.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
HKD1_k127_5796161_1	1123248.KB893314_gene3578	3.251e-215	675.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD1_k127_5796161_3	1122605.KB893648_gene3611	4.644e-141	455.0	COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,1IPHP@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
HKD1_k127_5814968_3	700598.Niako_0357	1.848e-32	127.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1IQIF@117747|Sphingobacteriia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD1_k127_5814968_0	700598.Niako_0358	1.132e-185	583.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1INY5@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HKD1_k127_5814968_1	700598.Niako_0359	3.765e-112	368.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1IPVG@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HKD1_k127_5814968_2	1123248.KB893316_gene4546	2.171e-58	209.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1IS9C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HKD1_k127_5828409_3	1121904.ARBP01000006_gene3964	1.03e-20	97.0	COG1524@1|root,COG3379@1|root,COG1524@2|Bacteria,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest,TPR_19
HKD1_k127_5828409_1	1237149.C900_02874	9.157e-43	167.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NTP_transf_5
HKD1_k127_5828409_0	926549.KI421517_gene1695	3.188e-60	223.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,47PUF@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5828409_2	313606.M23134_05409	3.278e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,4NK6N@976|Bacteroidetes,47SKA@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_5831093_2	929713.NIASO_19640	2.645e-94	315.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
HKD1_k127_5831093_1	929713.NIASO_18450	3.742e-161	511.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
HKD1_k127_5831093_3	700598.Niako_0137	9.532e-31	131.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1IUMP@117747|Sphingobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
HKD1_k127_5831093_0	1121481.AUAS01000001_gene4900	2.8e-322	1018.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
HKD1_k127_5842877_1	1144275.COCOR_02829	1.039e-40	156.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	yktD	GO:0002682,GO:0002684,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K16038	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09856	RC00003,RC02842	ko00000,ko00001,ko01000	-	-	-	LCM
HKD1_k127_5842877_0	1121875.KB907549_gene1914	1.692e-45	169.0	COG0657@1|root,COG0657@2|Bacteria,4NUK2@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
HKD1_k127_5842877_2	700598.Niako_7017	5.85e-14	72.0	COG0664@1|root,COG0664@2|Bacteria,4NQ1A@976|Bacteroidetes,1IY7M@117747|Sphingobacteriia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_5848503_20	1392498.JQLH01000001_gene610	1.591e-05	47.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2PI29@252356|Maribacter	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_5848503_13	1123248.KB893314_gene3699	1.165e-33	134.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5848503_4	558152.IQ37_04825	3.116e-88	299.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia,3ZTB1@59732|Chryseobacterium	976|Bacteroidetes	S	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
HKD1_k127_5848503_2	1267211.KI669560_gene2082	4.072e-175	555.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD1_k127_5848503_9	1123248.KB893314_gene3698	3.461e-45	175.0	COG0457@1|root,COG0457@2|Bacteria	1123248.KB893314_gene3698|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5848503_3	925409.KI911562_gene1879	1.899e-103	340.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD1_k127_5848503_6	700598.Niako_0345	1.165e-83	284.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1IRA0@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD1_k127_5848503_0	700598.Niako_0350	0.0	1199.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IQUU@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
HKD1_k127_5848503_15	866536.Belba_3220	7.746e-31	127.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,47S8T@768503|Cytophagia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD1_k127_5848503_8	1122605.KB893634_gene4219	5.321e-55	196.0	COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5848503_1	700598.Niako_3946	1.471e-185	582.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HKD1_k127_5848503_14	525257.HMPREF0204_15211	8.691e-32	128.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1I4DC@117743|Flavobacteriia,3ZSDU@59732|Chryseobacterium	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD1_k127_5848503_12	1191523.MROS_2390	5.312e-34	134.0	COG1993@1|root,COG1993@2|Bacteria	2|Bacteria	T	acr, cog1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
HKD1_k127_5848503_5	1122605.KB893647_gene483	5.386e-84	282.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HKD1_k127_5848503_11	1267211.KI669560_gene1519	3.925e-36	142.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5848503_7	700598.Niako_3952	5.099e-69	239.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_5848503_10	700598.Niako_0977	4.272e-45	168.0	COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD1_k127_5848503_17	1123248.KB893326_gene1409	3.454e-25	106.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia	976|Bacteroidetes	EGP	major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
HKD1_k127_5859684_1	1122931.AUAE01000003_gene201	1.802e-46	182.0	COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,2G0ER@200643|Bacteroidia,22ZB1@171551|Porphyromonadaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_16,TPR_7,TPR_8
HKD1_k127_5859684_0	471854.Dfer_1279	1.693e-52	194.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_5859684_2	1267211.KI669560_gene1621	6.892e-27	127.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5866359_0	925409.KI911562_gene1900	8.11e-196	621.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
HKD1_k127_5866359_1	991.IW20_08600	4.707e-19	100.0	COG1506@1|root,COG1506@2|Bacteria,4PKBT@976|Bacteroidetes,1IJ6T@117743|Flavobacteriia,2NSVC@237|Flavobacterium	976|Bacteroidetes	E	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
HKD1_k127_5868501_4	925409.KI911562_gene2283	4.495e-44	164.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD1_k127_5868501_2	1267211.KI669560_gene1953	2.753e-73	252.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD1_k127_5868501_1	700598.Niako_2171	1.512e-74	254.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,1IRSS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
HKD1_k127_5868501_3	700598.Niako_2170	6.409e-46	167.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD1_k127_5868501_0	700598.Niako_2169	3.921e-119	394.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
HKD1_k127_5868501_5	700598.Niako_2168	1.715e-07	53.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HKD1_k127_58757_1	929703.KE386491_gene2060	1.199e-79	272.0	COG3408@1|root,COG3408@2|Bacteria,4NHHR@976|Bacteroidetes,47MK4@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
HKD1_k127_58757_0	700598.Niako_2527	0.0	1380.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1INWR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
HKD1_k127_58757_2	925409.KI911562_gene2855	3.329e-36	138.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1IP4R@117747|Sphingobacteriia	976|Bacteroidetes	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HKD1_k127_5878583_2	925409.KI911562_gene2692	9.614e-10	68.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5878583_0	700598.Niako_0900	1.969e-86	296.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5878583_1	700598.Niako_0902	6.594e-27	110.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD1_k127_58835_0	925409.KI911562_gene2088	5.48e-234	727.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD1_k127_58835_2	700598.Niako_2452	9.153e-50	178.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1INWN@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
HKD1_k127_5883711_3	485918.Cpin_6595	9.236e-49	181.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1IVIF@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
HKD1_k127_5883711_4	700598.Niako_4499	9.055e-35	137.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
HKD1_k127_5883711_1	925409.KI911562_gene2790	8.336e-133	437.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
HKD1_k127_5883711_2	1123248.KB893319_gene4019	2.32e-121	407.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1IP2Z@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane protein involved in aromatic hydrocarbon degradation	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
HKD1_k127_5883711_5	1122605.KB893626_gene2713	6.466e-23	108.0	296FN@1|root,2ZTR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5883711_0	700598.Niako_1999	4.007e-268	835.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1IQ4M@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HKD1_k127_5883711_6	362418.IW19_06290	6.401e-22	101.0	2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I4Z6@117743|Flavobacteriia,2NWBJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
HKD1_k127_5883711_7	485918.Cpin_1682	1.525e-07	54.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1IRZA@117747|Sphingobacteriia	976|Bacteroidetes	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD1_k127_5899703_0	1123248.KB893327_gene808	1.207e-194	619.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1IY44@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_5899703_1	700598.Niako_0255	5.622e-124	400.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,1IWSD@117747|Sphingobacteriia	976|Bacteroidetes	M	COG2885 Outer membrane protein and related peptidoglycan-associated	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
HKD1_k127_5899919_3	1408473.JHXO01000008_gene2590	7.043e-09	57.0	COG3727@1|root,COG3727@2|Bacteria,4NQEH@976|Bacteroidetes,2FT9A@200643|Bacteroidia	976|Bacteroidetes	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
HKD1_k127_5899919_0	925409.KI911562_gene1340	8.497e-134	431.0	COG1402@1|root,COG1402@2|Bacteria,4PJ8H@976|Bacteroidetes,1J01R@117747|Sphingobacteriia	976|Bacteroidetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
HKD1_k127_5899919_1	714943.Mucpa_5289	1.099e-109	358.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1IP20@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5899919_2	714943.Mucpa_5290	1.15e-35	137.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1IR5Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_590696_4	531844.FIC_01929	8.264e-42	154.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1HX7N@117743|Flavobacteriia,405TM@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Male sterility protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_590696_2	929713.NIASO_01635	6.371e-143	458.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD1_k127_590696_1	1121889.AUDM01000003_gene2395	2.191e-176	558.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2NSCX@237|Flavobacterium	976|Bacteroidetes	GM	dehydratase	-	-	4.1.1.35,5.1.3.2,5.1.3.7	ko:K01784,ko:K02473,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD1_k127_590696_3	755732.Fluta_0731	6.291e-126	409.0	COG0451@1|root,COG0451@2|Bacteria,4NH7Y@976|Bacteroidetes,1I0N9@117743|Flavobacteriia,2PBG0@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD1_k127_590696_0	485918.Cpin_1090	8.277e-184	580.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1IQAV@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_5921766_0	867902.Ornrh_0091	0.0	1356.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD1_k127_5921766_7	118173.KB235914_gene1462	5.403e-35	157.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
HKD1_k127_5921766_2	1245469.S58_38650	4.172e-123	447.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
HKD1_k127_5921766_10	1206737.BAGF01000058_gene3766	1.419e-05	54.0	2B5K9@1|root,31YF9@2|Bacteria,2H0PR@201174|Actinobacteria,4G7YX@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5921766_5	700598.Niako_4053	9.562e-55	198.0	COG5263@1|root,COG5263@2|Bacteria,4PN8Y@976|Bacteroidetes,1J0PQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD1_k127_5921766_3	700598.Niako_0286	9.163e-111	371.0	COG3876@1|root,COG3876@2|Bacteria,4NKHR@976|Bacteroidetes,1IWXE@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD1_k127_5921766_4	925409.KI911562_gene2345	1.309e-84	282.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD1_k127_5921766_1	714943.Mucpa_4070	3.036e-307	951.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1IP5W@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock protein Hsp90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
HKD1_k127_5921766_6	700598.Niako_6510	1.333e-35	136.0	COG3304@1|root,COG3304@2|Bacteria,4NQSS@976|Bacteroidetes,1IXGC@117747|Sphingobacteriia	976|Bacteroidetes	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
HKD1_k127_5928136_1	1239962.C943_04282	3.764e-18	85.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_5928136_0	700598.Niako_5629	2.137e-284	876.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD1_k127_5932090_3	1123248.KB893316_gene4658	1.025e-98	327.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_5932090_6	700598.Niako_5462	3.546e-16	79.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1IR77@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD1_k127_5932090_5	1123248.KB893317_gene4315	2.084e-68	237.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1IR77@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD1_k127_5932090_1	700598.Niako_5461	6.615e-158	506.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
HKD1_k127_5932090_0	929713.NIASO_07635	1.389e-206	647.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1IVPN@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD1_k127_5932090_2	1122605.KB893643_gene823	1.606e-133	434.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1IPXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD1_k127_5932090_4	1267211.KI669560_gene1380	2.228e-96	317.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HKD1_k127_5940845_0	755732.Fluta_4062	9.625e-64	242.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NPAJ@976|Bacteroidetes,1IINS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_5942846_2	700598.Niako_6439	1.235e-99	329.0	COG1629@1|root,COG4771@2|Bacteria,4PN3U@976|Bacteroidetes,1J0TZ@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3
HKD1_k127_5942846_0	700598.Niako_6436	5.963e-264	843.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
HKD1_k127_5942846_1	1123248.KB893386_gene1824	1.574e-140	449.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD1_k127_5950803_3	700598.Niako_5798	2.289e-58	207.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
HKD1_k127_5950803_0	1122605.KB893626_gene2465	7.759e-227	710.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
HKD1_k127_5950803_2	1122605.KB893626_gene2464	4.372e-93	310.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD1_k127_5950803_1	925409.KI911562_gene378	3.405e-107	361.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_5971437_0	700598.Niako_6924	4.231e-88	294.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
HKD1_k127_5971437_1	1434325.AZQN01000014_gene1354	5.596e-39	153.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Amidase_2,Big_5,CBM60,CBM_5_12_2,DUF3494,Glyco_hydro_11,He_PIG,Malectin,PA14,PATR,VCBS
HKD1_k127_601896_4	1089547.KB913013_gene90	1.238e-73	273.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JQ1@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
HKD1_k127_601896_6	866536.Belba_2468	1.399e-34	143.0	2B99M@1|root,322KZ@2|Bacteria,4NS5P@976|Bacteroidetes,47QJC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_601896_0	1122605.KB893648_gene3615	1.508e-185	586.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1IWHP@117747|Sphingobacteriia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD1_k127_601896_5	1122605.KB893637_gene3155	9.137e-62	220.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,1ISSS@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
HKD1_k127_601896_1	1122605.KB893645_gene1091	1.16e-165	526.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1INZZ@117747|Sphingobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD1_k127_601896_2	929713.NIASO_07875	4.636e-162	520.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IR94@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_601896_3	926551.KB900719_gene288	1.581e-101	337.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia,1EQA6@1016|Capnocytophaga	976|Bacteroidetes	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HKD1_k127_6023631_1	1123248.KB893314_gene3716	1.529e-120	395.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1IPQQ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
HKD1_k127_6023631_2	700598.Niako_5402	5.367e-66	235.0	COG2135@1|root,COG2135@2|Bacteria,4P2FJ@976|Bacteroidetes,1IX8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HKD1_k127_6023631_3	925409.KI911562_gene390	1.119e-54	197.0	COG2318@1|root,COG2318@2|Bacteria,4NN7V@976|Bacteroidetes,1IY66@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
HKD1_k127_6023631_0	1121895.Q765_12310	8.089e-138	446.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1HXI9@117743|Flavobacteriia,2NTWF@237|Flavobacterium	976|Bacteroidetes	S	Dehydrogenase	-	-	1.1.1.1	ko:K13953,ko:K13979	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
HKD1_k127_6045541_6	700598.Niako_2053	1.677e-22	104.0	COG1196@1|root,COG1196@2|Bacteria,4PMEM@976|Bacteroidetes	976|Bacteroidetes	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
HKD1_k127_6045541_3	700598.Niako_2051	3.382e-68	234.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
HKD1_k127_6045541_2	1123248.KB893337_gene2464	2.981e-123	398.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
HKD1_k127_6045541_5	700598.Niako_2027	5.828e-66	228.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1ISBW@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HKD1_k127_6045541_4	925409.KI911562_gene2440	1.093e-67	237.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1IYXS@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
HKD1_k127_6045541_0	929713.NIASO_04720	5.095e-175	553.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
HKD1_k127_6045541_1	1122605.KB893625_gene2232	6.487e-140	452.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
HKD1_k127_6060496_5	1123248.KB893337_gene2525	7.36e-53	192.0	COG1538@1|root,COG1538@2|Bacteria,4NDZ6@976|Bacteroidetes,1IRPV@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_6060496_3	1121481.AUAS01000005_gene1822	3.464e-61	217.0	COG1309@1|root,COG1309@2|Bacteria,4NUB3@976|Bacteroidetes,47VTU@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD1_k127_6060496_2	700598.Niako_6955	3.499e-224	698.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
HKD1_k127_6060496_6	700598.Niako_6954	1.322e-44	166.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ITMH@117747|Sphingobacteriia	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD1_k127_6060496_0	925409.KI911562_gene1232	2.422e-298	931.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_6060496_1	700598.Niako_6951	5.592e-265	831.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
HKD1_k127_6060496_4	700598.Niako_6948	3.705e-60	210.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Chaperonin Cpn10	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
HKD1_k127_6069524_0	1317122.ATO12_20795	1.375e-74	254.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I872@117743|Flavobacteriia,2YGUU@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_6069524_3	700598.Niako_5678	1.614e-05	53.0	2CEPF@1|root,2ZR55@2|Bacteria,4P826@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6069524_2	700598.Niako_0642	1.33e-45	169.0	2CK2Y@1|root,32SBF@2|Bacteria	2|Bacteria	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
HKD1_k127_6069524_1	700598.Niako_0641	6.02e-62	214.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_6077977_2	1123248.KB893319_gene4022	3.11e-61	219.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,1IR5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD1_k127_6077977_1	700598.Niako_5626	1.423e-69	237.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes,1ISIG@117747|Sphingobacteriia	976|Bacteroidetes	I	COGs COG2185 Methylmalonyl-CoA mutase C-terminal domain subunit (cobalamin-binding)	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HKD1_k127_6077977_0	1454007.JAUG01000053_gene2497	1.744e-287	910.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,1IVR7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
HKD1_k127_6077977_3	1267211.KI669560_gene1052	8.939e-25	105.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD1_k127_6079570_0	760192.Halhy_0634	2.98e-100	362.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IW1C@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD1_k127_6079570_1	1268240.ATFI01000001_gene3165	5.656e-19	93.0	COG2199@1|root,COG3292@1|root,COG5002@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,2FXT6@200643|Bacteroidia,4AKCF@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
HKD1_k127_6092727_3	1185876.BN8_00276	1.277e-116	379.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
HKD1_k127_6092727_4	1185876.BN8_00275	2.681e-98	329.0	COG1940@1|root,COG1940@2|Bacteria,4NH8S@976|Bacteroidetes,47J9G@768503|Cytophagia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD1_k127_6092727_2	760192.Halhy_6817	1.777e-118	385.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD1_k127_6092727_0	1122605.KB893625_gene1603	6.267e-288	886.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1INXF@117747|Sphingobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD1_k127_6092727_5	1267211.KI669560_gene1240	3.862e-96	323.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IQB8@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
HKD1_k127_6092727_1	700598.Niako_7366	2.414e-233	733.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
HKD1_k127_6092727_6	1267211.KI669560_gene1235	4.518e-74	251.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1IQ0E@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HKD1_k127_6117965_0	1120951.AUBG01000002_gene1245	4.99e-10	73.0	COG1674@1|root,COG1674@2|Bacteria,4PMA8@976|Bacteroidetes,1I6B6@117743|Flavobacteriia	976|Bacteroidetes	D	ftsk spoiiie	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6121759_1	700598.Niako_6085	5.55e-31	124.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,OMP_b-brl,OMP_b-brl_2,OmpA
HKD1_k127_6121759_0	1267211.KI669560_gene628	1.215e-219	691.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPSY@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD1_k127_6144674_3	1137281.D778_00154	1.289e-12	73.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
HKD1_k127_6144674_1	700598.Niako_0915	1.318e-83	280.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1ISB1@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA methyltransferase, RsmD	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD1_k127_6144674_2	411154.GFO_3177	9.652e-35	139.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD1_k127_6144674_0	925409.KI911562_gene2411	1.339e-132	430.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HKD1_k127_6145177_1	1270193.JARP01000001_gene2235	1.128e-62	218.0	COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,1IJDM@117743|Flavobacteriia,2NSHF@237|Flavobacterium	976|Bacteroidetes	I	Releases the N-terminal proline from various substrates	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
HKD1_k127_6145177_0	1267211.KI669560_gene534	6.653e-166	535.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD1_k127_6180072_1	760192.Halhy_2468	7.519e-86	302.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
HKD1_k127_6180072_0	153721.MYP_2527	2.279e-90	321.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
HKD1_k127_6191401_1	700598.Niako_0116	6.724e-122	396.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HKD1_k127_6191401_2	700598.Niako_4512	4.955e-99	326.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6191401_3	1267211.KI669560_gene1527	1.201e-90	304.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
HKD1_k127_6191401_0	1267211.KI669560_gene1526	0.0	1063.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD1_k127_6194613_1	929556.Solca_4204	3.298e-114	384.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1IRJE@117747|Sphingobacteriia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
HKD1_k127_6194613_0	1239962.C943_01002	0.0	1273.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HKD1_k127_6208579_1	1123248.KB893314_gene3463	1.241e-117	385.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_6208579_0	760192.Halhy_2193	1.355e-283	896.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_6208579_2	1123248.KB893338_gene2304	6.185e-77	262.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,1IRTV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HKD1_k127_6235790_6	700598.Niako_6948	6.721e-60	209.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Chaperonin Cpn10	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
HKD1_k127_6235790_2	929713.NIASO_14675	7.653e-136	434.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1IP15@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_6235790_0	925409.KI911562_gene1224	6.052e-180	567.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD1_k127_6235790_3	929713.NIASO_19615	3.384e-95	316.0	COG2085@1|root,COG2085@2|Bacteria,4NPSZ@976|Bacteroidetes,1IYAV@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
HKD1_k127_6235790_8	700598.Niako_6944	5.651e-36	138.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes,1IU8Z@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6235790_5	700598.Niako_6942	6.331e-90	302.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,1ISDJ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_6235790_7	313612.L8106_18562	5.285e-47	174.0	COG2940@1|root,COG2940@2|Bacteria,1G6XB@1117|Cyanobacteria,1HCEZ@1150|Oscillatoriales	1117|Cyanobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
HKD1_k127_6235790_1	700598.Niako_6939	5.932e-156	497.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
HKD1_k127_6280502_2	411154.GFO_0344	0.0004444	48.0	2CG47@1|root,2ZAEC@2|Bacteria,4NI9X@976|Bacteroidetes,1HZZC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6280502_1	485918.Cpin_6737	2.812e-106	351.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IRKG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 16	-	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_16
HKD1_k127_6280502_0	760192.Halhy_1977	3.126e-235	732.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1IY44@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HKD1_k127_6287827_0	880073.Calab_3790	1.12e-62	224.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_6287827_1	1237149.C900_00727	4.729e-62	227.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
HKD1_k127_6287827_2	927658.AJUM01000034_gene567	6.792e-18	91.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6295681_0	929713.NIASO_19565	1.957e-269	839.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD1_k127_6295681_4	1122605.KB893630_gene4058	1.375e-35	138.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6295681_1	700598.Niako_7316	5.61e-133	429.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD1_k127_6295681_2	485918.Cpin_6970	2.907e-62	217.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HKD1_k127_6300284_0	700598.Niako_6295	2.677e-180	572.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
HKD1_k127_6300284_2	1123248.KB893331_gene3764	5.628e-44	163.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
HKD1_k127_6300284_1	118163.Ple7327_0446	5.093e-46	176.0	COG1805@1|root,COG1805@2|Bacteria,1G382@1117|Cyanobacteria,3VHZG@52604|Pleurocapsales	1117|Cyanobacteria	U	Na -transporting NADH ubiquinone oxidoreductase, subunit NqrB	-	-	-	-	-	-	-	-	-	-	-	-	NQR2_RnfD_RnfE
HKD1_k127_6304919_1	1454007.JAUG01000143_gene4625	2.709e-83	283.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1INMM@117747|Sphingobacteriia	976|Bacteroidetes	S	iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
HKD1_k127_6304919_0	700598.Niako_4051	2.201e-101	338.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IWNX@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6304919_4	700598.Niako_5770	8.13e-57	203.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
HKD1_k127_6304919_6	1227739.Hsw_3455	2.69e-21	98.0	COG2010@1|root,COG2010@2|Bacteria,4NVAQ@976|Bacteroidetes,47SR4@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6304919_3	700598.Niako_3288	1.31e-69	243.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
HKD1_k127_6304919_2	391603.FBALC1_16772	3.93e-70	248.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_6319986_3	700598.Niako_5668	1.927e-38	148.0	2CD0I@1|root,30JWK@2|Bacteria,4P4YR@976|Bacteroidetes,1IY9W@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
HKD1_k127_6319986_2	760192.Halhy_0012	8.584e-124	402.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,1IRK8@117747|Sphingobacteriia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
HKD1_k127_6319986_0	760192.Halhy_1192	7.48e-216	685.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
HKD1_k127_6319986_1	755732.Fluta_0208	1.403e-182	586.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia,2PAV4@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
HKD1_k127_6319986_4	700598.Niako_0935	7.745e-29	123.0	COG3631@1|root,COG3631@2|Bacteria,4P470@976|Bacteroidetes	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6344823_6	1122605.KB893649_gene3862	5.61e-44	164.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
HKD1_k127_6344823_3	700598.Niako_7349	1.364e-113	370.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
HKD1_k127_6344823_1	700598.Niako_7347	1.017e-151	495.0	2BV6Z@1|root,32QKE@2|Bacteria,4PCAH@976|Bacteroidetes,1IZE7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6344823_0	925409.KI911562_gene1470	0.0	1046.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
HKD1_k127_6344823_2	700598.Niako_7345	1.754e-135	434.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IVZZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HKD1_k127_6344823_5	929562.Emtol_1189	3.933e-48	175.0	COG3659@1|root,COG3659@2|Bacteria,4NHN1@976|Bacteroidetes,47MFC@768503|Cytophagia	976|Bacteroidetes	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K16080	-	-	-	-	ko00000,ko02000	1.B.4.2.2	-	-	OprB
HKD1_k127_6349991_3	700598.Niako_6444	5.354e-55	194.0	COG0745@1|root,COG0745@2|Bacteria,4NMAD@976|Bacteroidetes,1J08B@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_6349991_1	700598.Niako_6443	1.037e-120	408.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HKD1_k127_6349991_2	700598.Niako_6442	7.161e-59	214.0	28J3Q@1|root,2Z8ZW@2|Bacteria,4NGJW@976|Bacteroidetes,1IUBQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
HKD1_k127_6349991_4	1094466.KQS_01325	2.409e-52	192.0	COG1266@1|root,COG1266@2|Bacteria,4NPEG@976|Bacteroidetes,1I24G@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HKD1_k127_6349991_0	700598.Niako_6439	2.179e-243	772.0	COG1629@1|root,COG4771@2|Bacteria,4PN3U@976|Bacteroidetes,1J0TZ@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3
HKD1_k127_6354919_5	1267211.KI669560_gene2441	1.264e-67	235.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD1_k127_6354919_6	929713.NIASO_00070	1.175e-58	209.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1ITC4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD1_k127_6354919_7	700598.Niako_4542	5.845e-39	149.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1ITGX@117747|Sphingobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
HKD1_k127_6354919_0	1123248.KB893316_gene4651	0.0	1074.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD1_k127_6354919_4	700598.Niako_4539	9.293e-72	249.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISK8@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
HKD1_k127_6354919_3	700598.Niako_4538	1.117e-85	286.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HKD1_k127_6354919_1	1267211.KI669560_gene2056	2.792e-238	741.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_6354919_2	929713.NIASO_09750	4.906e-118	389.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,1IQHQ@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6360713_1	700598.Niako_5497	2.184e-34	133.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,1ISKK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HKD1_k127_6360713_0	700598.Niako_5499	1.598e-192	604.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1INTU@117747|Sphingobacteriia	976|Bacteroidetes	J	PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HKD1_k127_636183_0	1123248.KB893330_gene393	1.8e-131	436.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IPHQ@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
HKD1_k127_6363333_1	755732.Fluta_1926	1.125e-203	638.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PBC6@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_6363333_5	755732.Fluta_1927	1.296e-114	377.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD1_k127_6363333_8	700598.Niako_0154	1.678e-40	154.0	2EJD3@1|root,33834@2|Bacteria,4NVNH@976|Bacteroidetes,1ITYA@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
HKD1_k127_6363333_2	700598.Niako_0151	1.824e-196	619.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_6363333_3	700598.Niako_5480	3.416e-152	483.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD1_k127_6363333_0	700598.Niako_5481	6.415e-211	669.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
HKD1_k127_6363333_6	929713.NIASO_03890	6.312e-113	369.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IPT2@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
HKD1_k127_6363333_4	700598.Niako_5484	1.937e-149	480.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
HKD1_k127_6363333_9	700598.Niako_2668	3.774e-36	145.0	COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1IT5S@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_6363333_10	1120965.AUBV01000001_gene3351	2.021e-05	52.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
HKD1_k127_6363333_7	700598.Niako_4480	6.313e-82	284.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD1_k127_6366924_3	1379698.RBG1_1C00001G0109	2.264e-36	147.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HKD1_k127_6366924_0	1379698.RBG1_1C00001G0108	1.305e-86	296.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HKD1_k127_6366924_2	1379698.RBG1_1C00001G0107	1.393e-50	195.0	COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria	2|Bacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6366924_1	1267211.KI669560_gene2840	4.404e-80	268.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
HKD1_k127_6369277_2	1123248.KB893314_gene3622	7.9e-40	150.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,1ITFU@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6369277_6	1120965.AUBV01000008_gene1906	1.759e-14	73.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6369277_4	761193.Runsl_2699	2.606e-25	108.0	COG2442@1|root,COG2442@2|Bacteria,4NVPA@976|Bacteroidetes,47SHY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
HKD1_k127_6369277_3	761193.Runsl_2700	6.411e-27	113.0	COG4634@1|root,COG4634@2|Bacteria,4NXV1@976|Bacteroidetes,47SXR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6369277_7	1123057.P872_05890	0.0001393	44.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6369277_0	485918.Cpin_5844	5.569e-267	827.0	COG0753@1|root,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1IQ0M@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalase	-	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
HKD1_k127_6369277_5	1150600.ADIARSV_2377	3.31e-25	111.0	COG5499@1|root,COG5499@2|Bacteria,4NUII@976|Bacteroidetes,1IU9M@117747|Sphingobacteriia	976|Bacteroidetes	K	transcription regulator containing HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_6369277_1	1123277.KB893184_gene3953	3.684e-184	586.0	COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,47MIC@768503|Cytophagia	976|Bacteroidetes	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
HKD1_k127_6383966_0	391603.FBALC1_16772	3.364e-90	322.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_6383966_1	1408813.AYMG01000014_gene1509	2.482e-82	278.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1IQD0@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD1_k127_6391807_2	700598.Niako_2062	2.263e-16	87.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
HKD1_k127_6391807_0	1408473.JHXO01000009_gene3462	2.712e-85	293.0	COG3394@1|root,COG3394@2|Bacteria,4PNAT@976|Bacteroidetes,2G14M@200643|Bacteroidia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
HKD1_k127_6391807_1	700598.Niako_2074	4.857e-32	128.0	2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395633_5	866536.Belba_1302	1.032e-13	72.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD1_k127_6395633_3	929556.Solca_2235	2.76e-29	130.0	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395633_2	929556.Solca_2236	1.044e-36	142.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD1_k127_6395633_0	1121288.AULL01000011_gene1078	2.116e-241	752.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
HKD1_k127_6395633_1	945713.IALB_2618	2.749e-222	697.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD1_k127_6395633_4	700598.Niako_7222	2.71e-25	108.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6396301_4	1122605.KB893648_gene3582	1.622e-95	314.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_6396301_6	1158294.JOMI01000007_gene701	2.062e-36	141.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,2FU2H@200643|Bacteroidia	976|Bacteroidetes	S	tigr02436	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HKD1_k127_6396301_2	700598.Niako_1165	7.784e-307	945.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IWY5@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
HKD1_k127_6396301_5	700598.Niako_1166	1.72e-82	277.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
HKD1_k127_6396301_1	1123248.KB893332_gene2261	0.0	1373.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_6396301_3	1123248.KB893332_gene2262	8.171e-264	825.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	DUF4476,SusD-like_3,SusD_RagB
HKD1_k127_6396301_0	1123248.KB893332_gene2263	0.0	1581.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
HKD1_k127_6396301_7	1123248.KB893332_gene2268	1.208e-14	78.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Big_2,ChW,Glucosaminidase,Peptidase_C39_2,VCBS,YkuD
HKD1_k127_6411735_0	861299.J421_1886	1.992e-91	314.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
HKD1_k127_6411735_1	886377.Murru_3015	2.018e-41	158.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1I08M@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HKD1_k127_6420028_1	992406.RIA_1936	5.242e-50	181.0	COG0454@1|root,COG0454@2|Bacteria,4PM0R@976|Bacteroidetes,1IJIG@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD1_k127_6420028_3	172045.KS04_06605	0.00021	52.0	2DPS7@1|root,3335T@2|Bacteria,4NV9V@976|Bacteroidetes,1I5TH@117743|Flavobacteriia,34RZS@308865|Elizabethkingia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tox-MPTase3
HKD1_k127_6420028_2	700598.Niako_0042	1.204e-49	179.0	COG1917@1|root,COG1917@2|Bacteria,4NT85@976|Bacteroidetes,1IYIW@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6420028_4	1469557.JSWF01000030_gene3453	0.0008862	50.0	29MMH@1|root,308J8@2|Bacteria,4NP2P@976|Bacteroidetes,1I27T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6420028_0	1492737.FEM08_07980	5.878e-133	429.0	COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,1IMVG@117743|Flavobacteriia,2NV8X@237|Flavobacterium	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
HKD1_k127_6428559_2	700598.Niako_6665	2.292e-86	293.0	28NPZ@1|root,2ZBPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
HKD1_k127_6428559_4	700598.Niako_6664	7.452e-65	227.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,1J0EF@117747|Sphingobacteriia	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HKD1_k127_6428559_3	485918.Cpin_0915	1.25e-80	280.0	COG1073@1|root,COG1073@2|Bacteria,4NGG4@976|Bacteroidetes,1IXPI@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Hydrolase_4
HKD1_k127_6428559_0	1267211.KI669560_gene414	0.0	1110.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
HKD1_k127_6428559_1	700598.Niako_4127	2.006e-112	369.0	COG5002@1|root,COG5002@2|Bacteria,4NDTV@976|Bacteroidetes,1IPRG@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	covS	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS
HKD1_k127_6434281_0	700598.Niako_4325	3.016e-134	433.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_6434281_1	700598.Niako_4326	1.553e-118	385.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1IP6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD1_k127_6434281_2	700598.Niako_4328	1.797e-68	238.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_6453467_0	1267211.KI669560_gene2291	1.163e-89	304.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_6453467_2	929556.Solca_0286	1.425e-36	147.0	2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,1IUEQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6453467_1	1121887.AUDK01000022_gene2853	6.991e-85	292.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IG7Z@117743|Flavobacteriia,2NXGA@237|Flavobacterium	976|Bacteroidetes	M	Male sterility protein	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
HKD1_k127_6473258_0	925409.KI911562_gene646	0.0	1218.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
HKD1_k127_6473258_2	1123248.KB893319_gene4027	2.294e-231	721.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1IQJC@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD1_k127_6473258_6	700598.Niako_6100	3.391e-42	160.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1ISSY@117747|Sphingobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD1_k127_6473258_3	700598.Niako_6111	2.565e-199	627.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD1_k127_6473258_5	700598.Niako_6112	1.27e-43	162.0	COG2146@1|root,COG2146@2|Bacteria,4NV9E@976|Bacteroidetes,1ITVU@117747|Sphingobacteriia	976|Bacteroidetes	P	Rieske (2Fe-2S) domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske,Rieske_2
HKD1_k127_6473258_1	531844.FIC_00545	2.935e-253	790.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia,406XF@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Glycosyl-hydrolase 97 N-terminal	susB	GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
HKD1_k127_6480958_0	1341181.FLJC2902T_15860	2.667e-211	659.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1HZDD@117743|Flavobacteriia,2NU65@237|Flavobacterium	976|Bacteroidetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
HKD1_k127_6480958_1	700598.Niako_2122	2.221e-184	586.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
HKD1_k127_6480958_2	700598.Niako_5413	4.222e-35	138.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6487976_1	925409.KI911562_gene2901	2.378e-69	237.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1IQ26@117747|Sphingobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HKD1_k127_6487976_0	700598.Niako_0369	9.296e-74	259.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1IT79@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD1_k127_6489886_2	1434325.AZQN01000001_gene82	3.844e-64	221.0	COG3958@1|root,COG3958@2|Bacteria,4NFTS@976|Bacteroidetes,47KP0@768503|Cytophagia	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr
HKD1_k127_6489886_1	1434325.AZQN01000001_gene84	5.623e-95	319.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47MJ8@768503|Cytophagia	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD1_k127_6489886_3	5888.CAK91022	0.0001565	55.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
HKD1_k127_6489886_0	929703.KE386491_gene371	1.848e-97	337.0	COG4485@1|root,COG4485@2|Bacteria,4NUQF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HKD1_k127_6492632_1	1123248.KB893320_gene3944	7.627e-272	841.0	COG4102@1|root,COG4102@2|Bacteria,4PN6J@976|Bacteroidetes,1INVW@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
HKD1_k127_6492632_0	1123248.KB893320_gene3945	0.0	1129.0	COG2010@1|root,COG2010@2|Bacteria,4NFP6@976|Bacteroidetes,1IQMT@117747|Sphingobacteriia	976|Bacteroidetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,PSCyt1,PSCyt2,PSD1
HKD1_k127_6492632_2	457424.BFAG_01858	2.577e-10	73.0	COG4642@1|root,COG4642@2|Bacteria,4NJPY@976|Bacteroidetes,2FMDX@200643|Bacteroidia,4AMBW@815|Bacteroidaceae	976|Bacteroidetes	S	phosphatidylinositol-4-phosphate 5-kinase family protein K00889	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	MORN
HKD1_k127_6524036_1	700598.Niako_0920	1.392e-84	283.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD1_k127_6524036_0	700598.Niako_0919	1.683e-309	959.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD1_k127_6524036_2	700598.Niako_0918	3.992e-15	76.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
HKD1_k127_6529190_9	700598.Niako_0195	1.454e-11	68.0	2DREE@1|root,33BDM@2|Bacteria,4NXHP@976|Bacteroidetes	976|Bacteroidetes	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
HKD1_k127_6529190_8	700598.Niako_0194	1.579e-16	81.0	COG4980@1|root,COG4980@2|Bacteria,4NYR9@976|Bacteroidetes,1J0G6@117747|Sphingobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD1_k127_6529190_4	1123368.AUIS01000030_gene1248	7.301e-63	223.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD1_k127_6529190_5	468059.AUHA01000003_gene1724	7.37e-57	202.0	COG4119@1|root,COG4119@2|Bacteria,4NRRR@976|Bacteroidetes,1ITJZ@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_6529190_7	1123248.KB893316_gene4617	1.247e-24	108.0	2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes,1IZW7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6529190_2	468059.AUHA01000003_gene1716	9.047e-94	311.0	COG0500@1|root,COG2226@2|Bacteria,4NPPQ@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
HKD1_k127_6529190_0	1237149.C900_03080	6.3e-235	739.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
HKD1_k127_6529190_1	468059.AUHA01000003_gene1715	3.267e-126	414.0	COG1503@1|root,COG1503@2|Bacteria,4NHF3@976|Bacteroidetes,1IQW9@117747|Sphingobacteriia	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6529190_3	468059.AUHA01000003_gene1727	3.206e-88	296.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IWGA@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
HKD1_k127_6529190_6	1123248.KB893359_gene2201	2.759e-37	140.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD1_k127_6531701_0	504472.Slin_1257	1.893e-281	908.0	COG3940@1|root,COG3940@2|Bacteria,4PKWP@976|Bacteroidetes,47MYK@768503|Cytophagia	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
HKD1_k127_6531701_1	925409.KI911562_gene1687	7.049e-06	49.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_6554653_2	1450525.JATV01000001_gene2501	3.752e-06	49.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia,2NSVT@237|Flavobacterium	976|Bacteroidetes	S	nucleotide phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
HKD1_k127_6554653_0	1173024.KI912151_gene1625	0.0	1112.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD1_k127_6554653_1	404380.Gbem_0822	1.083e-275	859.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD1_k127_6561395_1	504472.Slin_3337	1.78e-110	364.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,47JA9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_6561395_2	700598.Niako_2954	5.385e-110	361.0	COG1028@1|root,COG1028@2|Bacteria,4NFU6@976|Bacteroidetes,1IVVF@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD1_k127_6561395_3	1123248.KB893315_gene3226	1.281e-104	347.0	COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,1IR6D@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I	vicX	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HKD1_k127_6561395_4	1123248.KB893381_gene1008	5.076e-100	338.0	COG3391@1|root,COG3391@2|Bacteria,4P26B@976|Bacteroidetes,1IX5X@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6561395_0	1279009.ADICEAN_03633	3.355e-147	474.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
HKD1_k127_6577900_1	1123277.KB893174_gene5928	1.348e-51	187.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_6577900_0	929713.NIASO_06535	2.884e-79	270.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD1_k127_6582145_2	1267211.KI669560_gene569	5.406e-17	82.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1IYKW@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
HKD1_k127_6582145_0	743722.Sph21_5015	4.564e-230	723.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IPEX@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_6582145_1	530564.Psta_4203	4.299e-47	173.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
HKD1_k127_6589695_1	700598.Niako_0315	4.747e-117	381.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1IQ3K@117747|Sphingobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
HKD1_k127_6589695_3	925409.KI911562_gene1921	1.834e-67	230.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1J0P2@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
HKD1_k127_6589695_0	1123248.KB893385_gene4811	1.361e-142	458.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD1_k127_6589695_2	929713.NIASO_08675	1.408e-80	276.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1IRHH@117747|Sphingobacteriia	976|Bacteroidetes	S	PASTA domain containing protein	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
HKD1_k127_6589695_4	925409.KI911562_gene2789	8.276e-46	167.0	COG0607@1|root,COG0607@2|Bacteria,4NVM6@976|Bacteroidetes,1IZ3G@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_6589695_5	1267211.KI669560_gene1397	7.015e-42	156.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1J0SA@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_6590322_6	1233950.IW22_17895	8.676e-22	95.0	COG4775@1|root,COG4775@2|Bacteria,4NRT9@976|Bacteroidetes,1I4PV@117743|Flavobacteriia,3ZTEA@59732|Chryseobacterium	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6590322_5	1250278.JQNQ01000001_gene3673	2.265e-42	167.0	292U1@1|root,2ZQBP@2|Bacteria,4NNH4@976|Bacteroidetes,1I28S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6590322_2	700598.Niako_0107	7.803e-222	693.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1INNU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
HKD1_k127_6590322_3	700598.Niako_0106	5.82e-212	661.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1IQ69@117747|Sphingobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HKD1_k127_6590322_7	1189619.pgond44_13102	1.929e-09	64.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1I19I@117743|Flavobacteriia,4C3RR@83612|Psychroflexus	976|Bacteroidetes	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
HKD1_k127_6590322_4	762903.Pedsa_2351	5.607e-97	320.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,1IP7C@117747|Sphingobacteriia	976|Bacteroidetes	E	synthase small subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HKD1_k127_6590322_1	1122621.ATZA01000025_gene2412	1.122e-301	933.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia	976|Bacteroidetes	EH	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HKD1_k127_6590322_0	1123248.KB893359_gene2131	1.963e-303	938.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1IPT9@117747|Sphingobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HKD1_k127_6592290_3	1210908.HSB1_14940	3.098e-37	145.0	COG1247@1|root,arCOG00830@2157|Archaea,2XXA1@28890|Euryarchaeota,23VUW@183963|Halobacteria	183963|Halobacteria	K	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
HKD1_k127_6592290_2	1123248.KB893341_gene830	2.462e-61	220.0	COG3279@1|root,COG3279@2|Bacteria,4NNUY@976|Bacteroidetes,1IXW8@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_6592290_1	1123248.KB893341_gene831	1.562e-62	228.0	COG2972@1|root,COG2972@2|Bacteria,4NMUF@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD1_k127_6592290_0	1550091.JROE01000013_gene125	1.388e-122	404.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1J0U5@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_659271_1	1122605.KB893637_gene3156	1.869e-141	461.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
HKD1_k127_659271_2	700598.Niako_2548	2.57e-89	297.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
HKD1_k127_659271_0	700598.Niako_2547	1.351e-167	531.0	COG2605@1|root,COG2605@2|Bacteria,4NHEN@976|Bacteroidetes,1IU21@117747|Sphingobacteriia	976|Bacteroidetes	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
HKD1_k127_659271_3	1123248.KB893317_gene4284	2.683e-73	250.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_6598170_2	700598.Niako_5590	2.43e-265	824.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD1_k127_6598170_0	700598.Niako_5592	0.0	1054.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HKD1_k127_6598170_5	1123248.KB893322_gene579	1.257e-29	121.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD1_k127_6598170_1	925409.KI911562_gene1184	8.881e-278	860.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1IQZ1@117747|Sphingobacteriia	976|Bacteroidetes	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD1_k127_6598170_3	1123248.KB893322_gene575	2.452e-52	188.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1ITCV@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD1_k127_6598170_6	925409.KI911562_gene1186	3.948e-18	85.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IUFV@117747|Sphingobacteriia	976|Bacteroidetes	U	Sec-independent protein translocase protein TatA	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
HKD1_k127_6598170_4	700598.Niako_5599	2.992e-44	164.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IQR9@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HKD1_k127_6607721_2	1122605.KB893648_gene3660	2.143e-88	308.0	28ICP@1|root,314Q6@2|Bacteria,4PIZD@976|Bacteroidetes,1IZ0B@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6607721_1	649349.Lbys_1143	4.478e-203	635.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HKD1_k127_6607721_0	700598.Niako_4718	0.0	1227.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HKD1_k127_6612192_0	700598.Niako_0921	2.073e-283	880.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
HKD1_k127_6612192_1	1123248.KB893316_gene4635	1.348e-105	347.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD1_k127_6612918_1	1123248.KB893326_gene1436	2.055e-53	191.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
HKD1_k127_6612918_3	1123248.KB893328_gene917	1.535e-20	94.0	COG3245@1|root,COG3245@2|Bacteria,4NRNS@976|Bacteroidetes,1IZF9@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612918_0	1123248.KB893328_gene918	1.01e-137	447.0	COG2960@1|root,COG2960@2|Bacteria,4NI9S@976|Bacteroidetes	976|Bacteroidetes	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612918_2	700598.Niako_5150	2.346e-35	139.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD1_k127_6618331_3	929713.NIASO_13330	3.347e-130	420.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HKD1_k127_6618331_12	700598.Niako_6596	4.073e-24	108.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD1_k127_6618331_7	1123248.KB893348_gene215	2.358e-73	250.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
HKD1_k127_6618331_0	700598.Niako_6594	0.0	1167.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
HKD1_k127_6618331_4	700598.Niako_6593	3.016e-129	416.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD1_k127_6618331_6	700598.Niako_6592	1.249e-116	382.0	COG3637@1|root,COG3637@2|Bacteria,4NNPF@976|Bacteroidetes,1ISTC@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
HKD1_k127_6618331_5	700598.Niako_6591	2.399e-128	415.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
HKD1_k127_6618331_2	1122605.KB893646_gene40	2.568e-131	434.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,1IWQ4@117747|Sphingobacteriia	976|Bacteroidetes	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
HKD1_k127_6618331_8	700598.Niako_6589	1.158e-67	236.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1IRUD@117747|Sphingobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_6618331_1	700598.Niako_6588	1.947e-145	463.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1INU7@117747|Sphingobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_6618331_10	700598.Niako_6587	5.587e-46	171.0	COG1286@1|root,COG1286@2|Bacteria,4P9DM@976|Bacteroidetes,1IZI5@117747|Sphingobacteriia	976|Bacteroidetes	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
HKD1_k127_6618331_9	700598.Niako_6586	2.021e-61	214.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD1_k127_6618331_11	1123248.KB893348_gene205	4.639e-41	154.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1ISTG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6618331_13	1123248.KB893348_gene204	3.445e-21	96.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1ITGA@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_6627758_0	938709.AUSH02000011_gene1187	1.05e-63	230.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes	976|Bacteroidetes	EG	of the drug metabolite transporter (DMT) superfamily	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_6627758_1	700598.Niako_5706	3.497e-59	207.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD1_k127_6630267_3	1123248.KB893315_gene3185	2.847e-39	147.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
HKD1_k127_6630267_4	929556.Solca_3605	4.024e-07	52.0	COG0262@1|root,COG0262@2|Bacteria,4NIN1@976|Bacteroidetes,1IRMK@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD1_k127_6630267_0	1341181.FLJC2902T_22430	7.502e-87	290.0	COG0262@1|root,COG0262@2|Bacteria,4NMP3@976|Bacteroidetes,1I84M@117743|Flavobacteriia,2P0EY@237|Flavobacterium	976|Bacteroidetes	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD1_k127_6630267_1	929713.NIASO_04820	6.846e-70	241.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1IT31@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
HKD1_k127_6630267_2	1237149.C900_02005	5.914e-45	166.0	COG0642@1|root,COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
HKD1_k127_6642183_0	1453500.AT05_01995	1.038e-117	416.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
HKD1_k127_6642183_2	41431.PCC8801_0005	1.085e-87	296.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
HKD1_k127_6642183_1	700598.Niako_6309	4.458e-96	318.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes	976|Bacteroidetes	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
HKD1_k127_6642183_5	1166018.FAES_4462	1.129e-17	87.0	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,47S7N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6642183_4	929713.NIASO_13410	9.891e-59	209.0	COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,1IT6N@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	fecI	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD1_k127_6642183_3	742767.HMPREF9456_01660	6.579e-75	258.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HKD1_k127_6649564_0	700598.Niako_2380	0.0	1007.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1IQRN@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14
HKD1_k127_6659752_0	468059.AUHA01000002_gene563	6.596e-71	266.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_6659752_1	509635.N824_06010	7.944e-10	60.0	COG0833@1|root,COG0833@2|Bacteria,4PN7J@976|Bacteroidetes,1IQ7E@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
HKD1_k127_6665532_1	585543.HMPREF0969_01915	3.18e-99	328.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,2FM8G@200643|Bacteroidia,4ANJT@815|Bacteroidaceae	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
HKD1_k127_6665532_0	435591.BDI_1870	1.85e-154	497.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes,2FWYJ@200643|Bacteroidia,22ZV9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_6665532_2	504472.Slin_0983	5.584e-13	70.0	COG2259@1|root,COG2259@2|Bacteria,4P48I@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
HKD1_k127_667340_3	925409.KI911562_gene1209	1.856e-14	73.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1IS01@117747|Sphingobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HKD1_k127_667340_0	929713.NIASO_14120	8.74e-65	226.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1ISWH@117747|Sphingobacteriia	976|Bacteroidetes	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD1_k127_667340_1	1121904.ARBP01000026_gene629	1.203e-43	163.0	COG3832@1|root,COG3832@2|Bacteria,4NRDQ@976|Bacteroidetes,47VV2@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_6675925_3	1341181.FLJC2902T_28550	1.878e-11	73.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6675925_0	760192.Halhy_3153	5.724e-275	861.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,1IPW5@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
HKD1_k127_6675925_1	118161.KB235922_gene2360	2.205e-107	365.0	COG1680@1|root,COG1680@2|Bacteria,1G5M7@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD1_k127_6675925_2	1341181.FLJC2902T_28550	2.875e-26	117.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6681345_0	700598.Niako_6842	2.094e-194	623.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1INX6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD1_k127_6681345_1	925409.KI911562_gene1144	1.779e-158	511.0	COG0531@1|root,COG0531@2|Bacteria,4NICM@976|Bacteroidetes,1IQNC@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_6681345_2	925409.KI911562_gene1145	9.788e-40	148.0	COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes,1IUQW@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
HKD1_k127_6692262_1	700598.Niako_5092	6.109e-21	94.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1IXNU@117747|Sphingobacteriia	976|Bacteroidetes	I	Ndr family	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_6692262_0	1123248.KB893315_gene3022	1.115e-278	882.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
HKD1_k127_6702366_0	1123248.KB893359_gene2061	6.847e-298	919.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD1_k127_6702366_1	700598.Niako_1009	4.316e-36	137.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD1_k127_6713775_3	925409.KI911562_gene588	7.344e-58	209.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD1_k127_6713775_1	929713.NIASO_14700	3.114e-91	313.0	COG0526@1|root,COG0526@2|Bacteria,4NQ06@976|Bacteroidetes,1ISI1@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
HKD1_k127_6713775_0	1122605.KB893646_gene199	1.627e-218	688.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1INQU@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HKD1_k127_6713775_2	1123248.KB893319_gene4064	3.61e-59	218.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD1_k127_672159_1	925409.KI911562_gene1612	1.142e-126	408.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD1_k127_672159_3	700598.Niako_5510	2.246e-73	252.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1IS44@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HKD1_k127_672159_0	925409.KI911562_gene1615	2.462e-238	743.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1IPKT@117747|Sphingobacteriia	976|Bacteroidetes	C	Dehydrogenase	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HKD1_k127_672159_2	700598.Niako_7305	3.263e-84	293.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,PorP_SprF,STN,TonB_dep_Rec
HKD1_k127_6728226_4	700598.Niako_6473	1.963e-05	47.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1IPBN@117747|Sphingobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6728226_3	700598.Niako_6472	2.161e-68	237.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
HKD1_k127_6728226_2	1122605.KB893626_gene2518	4.029e-96	317.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1ITKW@117747|Sphingobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
HKD1_k127_6728226_0	1122605.KB893626_gene2517	4.824e-288	887.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
HKD1_k127_6728226_1	1122605.KB893626_gene2516	1.893e-143	460.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
HKD1_k127_6744_0	1123277.KB893182_gene4766	5.783e-81	273.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KPV@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
HKD1_k127_6744_1	471854.Dfer_0731	3.034e-76	257.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia	976|Bacteroidetes	C	2Fe-2S -binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_6744_2	1267211.KI669560_gene2522	1.471e-32	132.0	COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,1J09D@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	aniA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
HKD1_k127_6744_3	278963.ATWD01000001_gene2461	3.061e-26	108.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_1,Cupin_2,DUF4440,HTH_18
HKD1_k127_6746725_0	1499967.BAYZ01000190_gene3842	1.942e-94	318.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
HKD1_k127_6746725_1	1267535.KB906767_gene4385	6.103e-20	93.0	2CK96@1|root,3346F@2|Bacteria,3Y5N2@57723|Acidobacteria,2JJZD@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6749493_0	929713.NIASO_16305	8.725e-200	627.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,1IVSR@117747|Sphingobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD1_k127_6749493_2	1123248.KB893348_gene153	6.453e-69	241.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1ITSR@117747|Sphingobacteriia	976|Bacteroidetes	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
HKD1_k127_6749493_1	700598.Niako_6312	1.781e-100	332.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1IRZ0@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
HKD1_k127_6749493_3	700598.Niako_6311	6.84e-23	108.0	COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1IR4N@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD1_k127_6750930_0	1123248.KB893348_gene137	5.322e-115	376.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1IRVU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HKD1_k127_6750930_1	700598.Niako_5812	2.898e-105	346.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1IP7N@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD1_k127_6752198_0	1121957.ATVL01000008_gene4646	1.06e-126	426.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_6752198_1	929713.NIASO_00340	9.532e-64	224.0	COG2197@1|root,COG2197@2|Bacteria,4NNQH@976|Bacteroidetes,1J05Y@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_6825828_0	1123037.AUDE01000012_gene171	1.704e-77	274.0	COG4676@1|root,COG4676@2|Bacteria,4NISW@976|Bacteroidetes,1I0BF@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0560
HKD1_k127_6825828_1	1137281.D778_02705	1.466e-38	156.0	COG5563@1|root,COG5563@2|Bacteria,4NMV9@976|Bacteroidetes,1I1RQ@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,TIG
HKD1_k127_6877277_2	1123277.KB893176_gene3731	9.545e-24	116.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_6877277_1	1123277.KB893176_gene3732	1.01e-145	476.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_6877277_0	1123277.KB893203_gene6259	3.369e-209	657.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD1_k127_6877277_4	1189612.A33Q_2377	5.044e-09	58.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,47MAD@768503|Cytophagia	976|Bacteroidetes	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
HKD1_k127_6913950_3	1034807.FBFL15_1424	1.81e-56	201.0	29BFF@1|root,2ZYDT@2|Bacteria,4PD2Y@976|Bacteroidetes,1IN9V@117743|Flavobacteriia,2NYPN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6913950_0	925409.KI911562_gene1189	0.0	1208.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_6913950_1	929713.NIASO_08915	9.675e-172	542.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD1_k127_6913950_6	1123248.KB893323_gene1572	4.577e-23	98.0	2ACFD@1|root,31210@2|Bacteria,4PGVP@976|Bacteroidetes,1IUGW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
HKD1_k127_6913950_5	1121875.KB907549_gene2135	1.035e-27	112.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HKD1_k127_6913950_4	700598.Niako_2582	4.589e-36	139.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD1_k127_6913950_2	700598.Niako_4385	2.08e-95	314.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
HKD1_k127_6925508_1	700598.Niako_4572	4.027e-94	313.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
HKD1_k127_6925508_4	700598.Niako_4571	3.867e-62	215.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1IT0E@117747|Sphingobacteriia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
HKD1_k127_6925508_2	1123248.KB893320_gene3933	5.407e-83	284.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1IRSV@117747|Sphingobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
HKD1_k127_6925508_0	700598.Niako_4568	2.581e-142	461.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1IP03@117747|Sphingobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD1_k127_6925508_5	1178825.ALIH01000017_gene651	1.335e-10	64.0	2E3YH@1|root,32YVH@2|Bacteria,4NWGM@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
HKD1_k127_6925508_3	925409.KI911562_gene1674	1.597e-77	264.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
HKD1_k127_6954829_3	925409.KI911562_gene21	6.517e-60	213.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
HKD1_k127_6954829_6	700598.Niako_5141	6.007e-51	184.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,1IT0H@117747|Sphingobacteriia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HKD1_k127_6954829_1	1122605.KB893649_gene3712	4.78e-77	266.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1IQMF@117747|Sphingobacteriia	976|Bacteroidetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
HKD1_k127_6954829_7	1341155.FSS13T_03410	1.632e-23	109.0	2BV77@1|root,32QKN@2|Bacteria,4PCAR@976|Bacteroidetes,1IMWW@117743|Flavobacteriia,2NVX6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6954829_8	1233950.IW22_09680	3.08e-14	79.0	COG4676@1|root,COG4676@2|Bacteria,4PGDK@976|Bacteroidetes,1IHDG@117743|Flavobacteriia,3ZU09@59732|Chryseobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6954829_5	938709.AUSH02000031_gene1221	2.509e-54	202.0	COG4676@1|root,COG4676@2|Bacteria,4NISW@976|Bacteroidetes	976|Bacteroidetes	M	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0560
HKD1_k127_6954829_9	880073.Calab_3296	3.825e-05	57.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
HKD1_k127_6954829_4	1499967.BAYZ01000045_gene2673	1.475e-55	217.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_6954829_0	1356852.N008_05325	3.255e-137	475.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
HKD1_k127_6954829_2	929713.NIASO_00340	6.072e-63	223.0	COG2197@1|root,COG2197@2|Bacteria,4NNQH@976|Bacteroidetes,1J05Y@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_6968603_1	1237149.C900_02005	4.985e-138	451.0	COG0642@1|root,COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
HKD1_k127_6968603_0	1123248.KB893321_gene544	1.932e-162	515.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_6974177_5	1121373.KB903654_gene1527	7.952e-06	49.0	2ENII@1|root,33G5Y@2|Bacteria,4NXIB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6974177_2	700598.Niako_2403	1.524e-18	87.0	2DP5Z@1|root,330NW@2|Bacteria,4NV0Q@976|Bacteroidetes,1IUKB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6974177_4	1233951.IO90_08480	1.322e-06	53.0	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6974177_1	1121288.AULL01000002_gene2107	1.307e-30	124.0	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6974177_0	1492738.FEM21_02140	1.272e-116	381.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia,2NUZN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7026872_5	700598.Niako_5072	9.744e-99	327.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_7026872_6	1185876.BN8_04128	5.345e-40	158.0	COG2227@1|root,COG2227@2|Bacteria,4PNA0@976|Bacteroidetes,47KG3@768503|Cytophagia	976|Bacteroidetes	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD1_k127_7026872_3	700598.Niako_5100	2.926e-116	376.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_7026872_0	700598.Niako_5103	1.601e-128	416.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,1IXIC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
HKD1_k127_7026872_4	700598.Niako_5104	2.334e-107	351.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HKD1_k127_7026872_2	700598.Niako_5106	3.258e-118	382.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD1_k127_7026872_1	700598.Niako_5107	4.463e-124	400.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD1_k127_7026872_7	700598.Niako_5109	2.161e-28	117.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
HKD1_k127_7053180_4	1123278.KB893394_gene5378	5.947e-06	51.0	COG3668@1|root,COG3668@2|Bacteria,4NZFW@976|Bacteroidetes,47SQM@768503|Cytophagia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HKD1_k127_7053180_0	700598.Niako_1613	0.0	1297.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
HKD1_k127_7053180_2	700598.Niako_1620	5.533e-71	247.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HKD1_k127_7053180_1	1123248.KB893326_gene1510	8.487e-134	430.0	COG2207@1|root,COG4275@1|root,COG2207@2|Bacteria,COG4275@2|Bacteria,4NIZN@976|Bacteroidetes,1IQES@117747|Sphingobacteriia	976|Bacteroidetes	K	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,HTH_18
HKD1_k127_7053180_3	929556.Solca_1499	4.255e-57	200.0	COG4275@1|root,COG4275@2|Bacteria,4PKPP@976|Bacteroidetes,1IX8W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
HKD1_k127_7054790_1	1123248.KB893330_gene392	6.698e-56	198.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_7054790_0	925409.KI911562_gene751	9.304e-65	230.0	COG1376@1|root,COG1376@2|Bacteria,4NNMF@976|Bacteroidetes,1J0D6@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
HKD1_k127_7054790_2	1131812.JQMS01000001_gene2157	3.004e-27	120.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia,2NWFB@237|Flavobacterium	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
HKD1_k127_7061585_1	869213.JCM21142_104359	1.236e-38	150.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Rhodanese
HKD1_k127_7061585_0	925409.KI911562_gene2309	4.886e-230	719.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IUT4@117747|Sphingobacteriia	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	czcA_1	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
HKD1_k127_7064807_0	700598.Niako_0166	6.107e-178	569.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
HKD1_k127_7064807_2	700598.Niako_0167	6.651e-104	340.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
HKD1_k127_7064807_1	700598.Niako_0168	4.891e-149	476.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD1_k127_7064807_3	700598.Niako_0169	4.215e-25	110.0	COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,1IZ9G@117747|Sphingobacteriia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7074323_2	509635.N824_27510	2.791e-109	356.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,1IRCG@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD1_k127_7074323_1	761193.Runsl_1670	7.1e-111	363.0	COG1028@1|root,COG1028@2|Bacteria,4NF64@976|Bacteroidetes,47MEC@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD1_k127_7074323_0	929713.NIASO_17560	2.702e-127	413.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_7074323_3	1267211.KI669560_gene463	1.335e-58	207.0	COG0657@1|root,COG4099@1|root,COG0657@2|Bacteria,COG4099@2|Bacteria,4PKKH@976|Bacteroidetes,1J0WF@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
HKD1_k127_7077679_5	700598.Niako_6628	1.765e-13	71.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1IQ8K@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD1_k127_7077679_0	925409.KI911562_gene616	4.823e-142	456.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1IVKB@117747|Sphingobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
HKD1_k127_7077679_3	700598.Niako_6633	1.23e-86	299.0	COG1629@1|root,COG1629@2|Bacteria,4NQGN@976|Bacteroidetes,1ITAT@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD1_k127_7077679_1	700598.Niako_6634	1.118e-137	445.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
HKD1_k127_7077679_2	700598.Niako_6635	1.295e-109	361.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes	976|Bacteroidetes	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD1_k127_7077679_4	1122605.KB893646_gene34	2.71e-63	223.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1IQ8Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HKD1_k127_7083078_3	929713.NIASO_12850	1.464e-14	77.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ITT6@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
HKD1_k127_7083078_0	509635.N824_05990	2.269e-239	745.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IPQB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_7083078_2	485917.Phep_1237	1.491e-89	301.0	COG2071@1|root,COG2071@2|Bacteria,4NNEJ@976|Bacteroidetes,1IS4X@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
HKD1_k127_7083078_1	509635.N824_06000	1.543e-167	528.0	COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,1ISP5@117747|Sphingobacteriia	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HKD1_k127_7093105_4	1122605.KB893644_gene1513	1.135e-51	186.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
HKD1_k127_7093105_3	700598.Niako_5809	8.016e-67	235.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_7093105_1	1123248.KB893314_gene3423	2.929e-123	410.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_7093105_2	925409.KI911562_gene577	1.932e-104	351.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
HKD1_k127_7093105_0	1267211.KI669560_gene295	0.0	1447.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
HKD1_k127_7093105_5	700598.Niako_5414	5.605e-24	104.0	2CWBN@1|root,316DW@2|Bacteria,4PBEY@976|Bacteroidetes,1J02S@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7101183_1	1453505.JASY01000024_gene295	6.244e-68	244.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXNE@117743|Flavobacteriia,2NT5A@237|Flavobacterium	976|Bacteroidetes	P	Tonb-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_7101183_0	929556.Solca_3818	1.802e-81	279.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8
HKD1_k127_7110467_1	1237149.C900_02421	2.383e-65	233.0	COG2187@1|root,COG2187@2|Bacteria,4P2MP@976|Bacteroidetes,47UQI@768503|Cytophagia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7110467_0	1123248.KB893326_gene1434	1.627e-87	294.0	COG1926@1|root,COG1926@2|Bacteria,4NRU7@976|Bacteroidetes,1IYRM@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
HKD1_k127_7110467_2	1123248.KB893326_gene1435	1.926e-16	80.0	COG2843@1|root,COG2843@2|Bacteria,4NI9W@976|Bacteroidetes,1J0CU@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HKD1_k127_7119999_1	700598.Niako_6082	1.035e-162	514.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
HKD1_k127_7119999_2	929562.Emtol_0801	3.521e-143	460.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
HKD1_k127_7119999_4	929713.NIASO_14925	5.878e-133	429.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
HKD1_k127_7119999_0	700598.Niako_6084	4.364e-163	517.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD1_k127_7119999_3	700598.Niako_6086	1.514e-140	469.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1IPZ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD1_k127_7119999_5	485918.Cpin_0863	1.338e-11	68.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IXCQ@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
HKD1_k127_7129081_0	700598.Niako_1111	3.162e-94	335.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,1IT0V@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
HKD1_k127_7129081_1	468059.AUHA01000002_gene563	5.087e-91	313.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
HKD1_k127_7136657_0	1150600.ADIARSV_2929	2.966e-31	131.0	COG1969@1|root,COG1969@2|Bacteria,4PNWG@976|Bacteroidetes,1IU7I@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
HKD1_k127_7160540_3	1454007.JAUG01000085_gene3261	2.71e-25	111.0	2AE6H@1|root,2ZYG3@2|Bacteria,4NPIR@976|Bacteroidetes,1J14P@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7160540_1	1408813.AYMG01000001_gene3392	1.092e-80	273.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1IXX6@117747|Sphingobacteriia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
HKD1_k127_7160540_0	700598.Niako_4449	0.0	1227.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_7160540_2	925409.KI911562_gene2809	9.997e-54	194.0	COG2849@1|root,COG2849@2|Bacteria,4NZNQ@976|Bacteroidetes	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
HKD1_k127_7168053_1	700598.Niako_5568	5.342e-90	299.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	rgpC	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
HKD1_k127_7168053_0	700598.Niako_5569	8.118e-123	397.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1IPVR@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG1134 ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran,Wzt_C
HKD1_k127_7168053_2	700598.Niako_5570	1.069e-81	287.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
HKD1_k127_7168053_3	313606.M23134_08430	5.102e-70	246.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
HKD1_k127_7174309_0	1121875.KB907550_gene639	1.068e-154	522.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
HKD1_k127_7178441_1	1107311.Q767_13950	7.102e-39	153.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD1_k127_7178441_10	1341181.FLJC2902T_28550	7.371e-12	75.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7178441_7	1492737.FEM08_21720	1.368e-23	109.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7178441_8	1341181.FLJC2902T_28550	3.68e-23	109.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7178441_6	1341181.FLJC2902T_28550	2.129e-25	115.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7178441_9	1341181.FLJC2902T_28550	4.966e-22	105.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7178441_0	700598.Niako_6457	5.105e-234	734.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD1_k127_7185200_1	925409.KI911562_gene60	5.414e-233	730.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
HKD1_k127_7185200_2	925409.KI911562_gene59	1.664e-196	619.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
HKD1_k127_7185200_6	1122605.KB893625_gene1989	5.063e-114	371.0	COG0586@1|root,COG0586@2|Bacteria,4NMPN@976|Bacteroidetes,1IWBE@117747|Sphingobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
HKD1_k127_7185200_4	1123248.KB893332_gene2278	1.521e-178	567.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_7185200_3	925409.KI911562_gene54	1.186e-182	573.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
HKD1_k127_7185200_10	929713.NIASO_09400	1.549e-37	146.0	COG0526@1|root,COG0526@2|Bacteria,4NV2M@976|Bacteroidetes,1IUG8@117747|Sphingobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
HKD1_k127_7185200_7	929713.NIASO_19635	2.45e-97	320.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD1_k127_7185200_8	929713.NIASO_19630	9.266e-58	205.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD1_k127_7185200_0	925409.KI911562_gene1538	1.357e-264	817.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1INM0@117747|Sphingobacteriia	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD1_k127_7185200_5	925409.KI911562_gene1119	6.245e-142	465.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_7185200_9	391603.FBALC1_03312	8.84e-45	173.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HKD1_k127_7186543_0	700598.Niako_6434	2.213e-222	703.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
HKD1_k127_7186543_1	925409.KI911562_gene878	1.941e-199	634.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HKD1_k127_7198595_0	700598.Niako_4725	0.0	1272.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD1_k127_7198595_2	929713.NIASO_01615	2.513e-92	308.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,1ISX6@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HKD1_k127_7198595_1	700598.Niako_4582	2.015e-141	455.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HKD1_k127_7198595_3	1123248.KB893323_gene1605	2.563e-63	220.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1IV2A@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
HKD1_k127_7236588_0	1239962.C943_01101	7.336e-106	372.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47N98@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
HKD1_k127_7237256_0	925409.KI911562_gene944	5.937e-49	176.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD1_k127_7237256_2	945713.IALB_0126	1.136e-23	104.0	arCOG10456@1|root,2ZA6T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7237256_1	926556.Echvi_1100	6.664e-26	116.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,47TC5@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, crp family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_7264725_0	929562.Emtol_4148	0.0	1513.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_7264725_2	592029.DDD_1985	1.695e-05	57.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,4PDT9@976|Bacteroidetes,1IE6Z@117743|Flavobacteriia,3HKZK@363408|Nonlabens	976|Bacteroidetes	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
HKD1_k127_7264725_1	1449357.JQLK01000001_gene1667	1.689e-41	172.0	2A1UA@1|root,30Q39@2|Bacteria,1WM6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7286930_0	1408813.AYMG01000030_gene676	2.851e-81	291.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1J0QK@117747|Sphingobacteriia	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
HKD1_k127_7287018_3	485918.Cpin_0416	1.312e-35	139.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1IUC4@117747|Sphingobacteriia	976|Bacteroidetes	J	Class I peptide chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
HKD1_k127_7287018_1	1267211.KI669560_gene2746	6.301e-215	677.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1IPM6@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
HKD1_k127_7287018_2	700598.Niako_5656	5.959e-92	306.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,1J079@117747|Sphingobacteriia	976|Bacteroidetes	P	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_7287018_0	1123248.KB893386_gene1983	0.0	1322.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,1IV8M@117747|Sphingobacteriia	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40
HKD1_k127_7315589_2	700598.Niako_2625	1.84e-72	250.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
HKD1_k127_7315589_0	925409.KI911562_gene1463	5.53e-322	991.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
HKD1_k127_7315589_1	760192.Halhy_0452	4.876e-201	636.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1IV4P@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG1523 Type II secretory pathway pullulanase PulA and related glycosidase	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HKD1_k127_7347925_7	925409.KI911562_gene235	4.222e-26	112.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
HKD1_k127_7347925_3	700598.Niako_7029	5.928e-139	449.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD1_k127_7347925_1	929713.NIASO_18180	4.688e-151	491.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
HKD1_k127_7347925_6	700598.Niako_7031	6.915e-43	168.0	2E469@1|root,32Z27@2|Bacteria,4P4UV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7347925_5	700598.Niako_7032	1.3e-67	231.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1ISF1@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
HKD1_k127_7347925_2	700598.Niako_7033	6.292e-147	469.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_7347925_0	929713.NIASO_18265	2.899e-242	752.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1INMC@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD1_k127_7347925_4	700598.Niako_7035	1.099e-67	233.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD1_k127_7347925_8	700598.Niako_3229	0.0002695	50.0	2EGT8@1|root,33AJC@2|Bacteria,4NY9U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7361336_1	700598.Niako_5783	1.626e-231	726.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1IP42@117747|Sphingobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
HKD1_k127_7361336_2	1123248.KB893319_gene4046	1.292e-201	649.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1IQH4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
HKD1_k127_7361336_0	1123248.KB893315_gene2998	0.0	1166.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,1IQ4S@117747|Sphingobacteriia	976|Bacteroidetes	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
HKD1_k127_7361336_3	1123248.KB893319_gene4048	4.958e-145	472.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7361336_4	925409.KI911562_gene1107	4.374e-12	66.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
HKD1_k127_737304_2	1122605.KB893633_gene4265	9.698e-48	175.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HKD1_k127_737304_1	925409.KI911562_gene2636	2.868e-76	264.0	COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IZ4H@117747|Sphingobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
HKD1_k127_737304_0	1123248.KB893326_gene1511	4.259e-138	445.0	COG1388@1|root,COG1388@2|Bacteria,4NISJ@976|Bacteroidetes	976|Bacteroidetes	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
HKD1_k127_7380033_0	1121889.AUDM01000002_gene337	2.574e-149	506.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NVE3@237|Flavobacterium	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD1_k127_7380033_1	700598.Niako_4749	4.209e-72	257.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
HKD1_k127_7425881_2	925409.KI911562_gene942	1.578e-09	58.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1IRBN@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
HKD1_k127_7425881_0	925409.KI911562_gene943	4.322e-111	364.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1IPBT@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
HKD1_k127_7425881_1	925409.KI911562_gene944	3.198e-100	331.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
HKD1_k127_743133_1	376686.Fjoh_4121	3.726e-121	392.0	COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia,2NSD7@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD1_k127_743133_0	925409.KI911562_gene39	1.789e-165	529.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1INV5@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
HKD1_k127_743133_2	1296415.JACC01000037_gene1112	4.553e-26	114.0	COG3534@1|root,COG3979@1|root,COG4447@1|root,COG5295@1|root,COG3534@2|Bacteria,COG3979@2|Bacteria,COG4447@2|Bacteria,COG5295@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2YM66@290174|Aquimarina	976|Bacteroidetes	UW	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
HKD1_k127_743133_3	435590.BVU_2433	9.963e-22	100.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,2FM7K@200643|Bacteroidia,4AP20@815|Bacteroidaceae	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
HKD1_k127_74483_0	700598.Niako_6538	0.0	1064.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
HKD1_k127_7449185_1	1189620.AJXL01000023_gene2918	3.667e-72	259.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2NSNJ@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD1_k127_7449185_2	1267211.KI669560_gene1229	8.491e-71	242.0	COG1247@1|root,COG1247@2|Bacteria,4PM4N@976|Bacteroidetes,1ISGA@117747|Sphingobacteriia	976|Bacteroidetes	M	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_7449185_0	700598.Niako_5085	1.441e-217	684.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IVVS@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
HKD1_k127_746334_3	700598.Niako_1169	2.01e-49	179.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1IT04@117747|Sphingobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
HKD1_k127_746334_1	1267211.KI669560_gene1758	4.201e-80	268.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD1_k127_746334_0	929713.NIASO_04035	3.168e-168	532.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD1_k127_746334_4	925409.KI911562_gene1798	5.23e-36	142.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
HKD1_k127_746334_2	1123248.KB893332_gene2268	3.675e-67	231.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Big_2,ChW,Glucosaminidase,Peptidase_C39_2,VCBS,YkuD
HKD1_k127_747784_5	485917.Phep_3853	2.373e-56	201.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1ISCA@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD1_k127_747784_0	1150600.ADIARSV_2511	0.0	1719.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD1_k127_747784_8	1453500.AT05_07905	1.988e-45	167.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HKD1_k127_747784_2	1123248.KB893381_gene1004	2.547e-213	669.0	COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1IR8C@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_747784_6	700598.Niako_2045	3.084e-53	191.0	COG0607@1|root,COG0607@2|Bacteria,4NR99@976|Bacteroidetes,1ITDD@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_747784_3	714943.Mucpa_3893	8.164e-102	349.0	COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes,1IVBY@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_747784_1	700598.Niako_5647	1.535e-264	820.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1IPE0@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HKD1_k127_747784_7	1168034.FH5T_08000	3.328e-48	174.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,2FT28@200643|Bacteroidia	976|Bacteroidetes	J	MazG nucleotide pyrophosphohydrolase domain protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
HKD1_k127_747784_4	143224.JQMD01000002_gene2272	3.579e-70	240.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD1_k127_747784_9	485918.Cpin_0416	6.374e-11	66.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1IUC4@117747|Sphingobacteriia	976|Bacteroidetes	J	Class I peptide chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
HKD1_k127_7486957_0	700598.Niako_6560	6.646e-56	196.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1IQ9R@117747|Sphingobacteriia	976|Bacteroidetes	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HKD1_k127_7486957_3	616991.JPOO01000003_gene1212	1.643e-11	72.0	2DTH4@1|root,33KAP@2|Bacteria,4NYZ8@976|Bacteroidetes,1IBJQ@117743|Flavobacteriia,23IDD@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7498306_0	925409.KI911562_gene684	5.551e-148	473.0	COG1181@1|root,COG2940@1|root,COG1181@2|Bacteria,COG2940@2|Bacteria,4P8F6@976|Bacteroidetes	2|Bacteria	M	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Ank,Dala_Dala_lig_C,Dala_Dala_lig_N,SET
HKD1_k127_7498306_1	925409.KI911562_gene685	1.743e-139	449.0	COG4988@1|root,COG4988@2|Bacteria	2|Bacteria	V	cysteine transport	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	AAA_11,AAA_12,ABC_membrane,ABC_membrane_3,ABC_tran,DUF4011,cNMP_binding
HKD1_k127_7498306_2	1469557.JSWF01000030_gene3459	7.615e-34	134.0	COG0457@1|root,COG0590@1|root,COG1680@1|root,COG0457@2|Bacteria,COG0590@2|Bacteria,COG1680@2|Bacteria,4NJ5G@976|Bacteroidetes,1HX8E@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302,TPR_2
HKD1_k127_7520159_1	1267211.KI669560_gene2037	5.175e-111	362.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HKD1_k127_7520159_0	1122605.KB893627_gene2879	7.048e-129	415.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HKD1_k127_7569408_2	700598.Niako_1004	4.829e-68	237.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HKD1_k127_7569408_4	929713.NIASO_02945	3.346e-41	154.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1ITXA@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HKD1_k127_7569408_5	700598.Niako_1006	2.423e-29	124.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes	976|Bacteroidetes	M	InterPro IPR011467	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
HKD1_k127_7569408_1	929713.NIASO_02955	8.301e-114	374.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1ISHE@117747|Sphingobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD1_k127_7569408_3	925409.KI911562_gene2317	6.06e-47	169.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1ITF1@117747|Sphingobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD1_k127_7569408_0	925409.KI911562_gene2316	4.898e-216	675.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD1_k127_7575863_3	700598.Niako_7332	7.279e-18	83.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD1_k127_7575863_0	929713.NIASO_11550	2.923e-168	533.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
HKD1_k127_7575863_1	700598.Niako_5014	1.146e-99	348.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1IS4A@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
HKD1_k127_7575863_2	1150600.ADIARSV_1523	1.936e-23	113.0	2C5U1@1|root,2Z80K@2|Bacteria,4NG4G@976|Bacteroidetes,1IQ1S@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7583506_4	700598.Niako_5087	1.747e-76	261.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1IQBR@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD1_k127_7583506_0	929713.NIASO_08640	2.143e-169	536.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD1_k127_7583506_3	1279009.ADICEAN_01399	1.25e-85	302.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HKD1_k127_7583506_5	1123248.KB893322_gene598	3.523e-53	193.0	COG2318@1|root,COG2318@2|Bacteria,4NPSF@976|Bacteroidetes	976|Bacteroidetes	S	Pfam DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
HKD1_k127_7583506_1	925409.KI911562_gene1496	2.645e-169	543.0	COG0626@1|root,COG0626@2|Bacteria,4NJRK@976|Bacteroidetes,1IP3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HKD1_k127_7583506_2	1239962.C943_03721	1.444e-166	543.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,47NUP@768503|Cytophagia	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
HKD1_k127_7594238_1	172088.AUGA01000016_gene2484	9.177e-45	169.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria,3K0V6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_7594238_0	1122605.KB893649_gene3854	2.156e-174	556.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1INVX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
HKD1_k127_7602701_2	700598.Niako_6673	1.571e-50	186.0	COG1250@1|root,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.108,1.1.1.157	ko:K00074,ko:K17735	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,4HBT_2
HKD1_k127_7602701_1	1122605.KB893626_gene2655	6.681e-55	196.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes	976|Bacteroidetes	J	endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HKD1_k127_7602701_0	929713.NIASO_15795	3.271e-101	336.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes,1INW3@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD1_k127_7638796_0	714943.Mucpa_5067	0.0	1222.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1INYN@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
HKD1_k127_7638796_1	926549.KI421517_gene3916	4.883e-100	336.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47N9W@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB_1	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
HKD1_k127_7675187_2	1408813.AYMG01000039_gene2310	3.757e-16	84.0	COG1538@1|root,COG1538@2|Bacteria,4NKWK@976|Bacteroidetes,1IQ86@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_7675187_1	1123248.KB893326_gene1286	5.835e-113	374.0	COG3391@1|root,COG3391@2|Bacteria,4NJZS@976|Bacteroidetes,1IS74@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
HKD1_k127_7675187_0	700598.Niako_6637	2.354e-170	542.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD1_k127_7680290_3	700598.Niako_1693	1.032e-55	197.0	COG3874@1|root,COG3874@2|Bacteria,4NTIV@976|Bacteroidetes,1ITIB@117747|Sphingobacteriia	976|Bacteroidetes	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HKD1_k127_7680290_5	700598.Niako_1694	4.713e-33	134.0	2C8EV@1|root,32RM1@2|Bacteria,4NU8V@976|Bacteroidetes,1IZYA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7680290_0	1189612.A33Q_4560	1.37e-185	587.0	COG4030@1|root,COG4030@2|Bacteria,4NHV9@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
HKD1_k127_7680290_1	929562.Emtol_0722	1.281e-129	420.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,TAT_signal
HKD1_k127_7680290_4	929703.KE386491_gene1228	5.131e-42	158.0	2C85M@1|root,31482@2|Bacteria,4NS0C@976|Bacteroidetes,47QCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
HKD1_k127_7680290_2	1123248.KB893359_gene2164	9.191e-85	286.0	2EPP0@1|root,33H9M@2|Bacteria,4NXT6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_0	925409.KI911562_gene2713	8.968e-237	737.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1IP0Q@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HKD1_k127_7689016_7	714943.Mucpa_7012	1.407e-23	106.0	2DBIE@1|root,32TXH@2|Bacteria,4NSJE@976|Bacteroidetes,1ITSC@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_9	445961.IW15_16185	4.635e-11	68.0	2EAT9@1|root,334V5@2|Bacteria,4NUP8@976|Bacteroidetes,1I6RQ@117743|Flavobacteriia,3ZT0R@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_6	700598.Niako_0889	3.34e-64	231.0	2EPP0@1|root,33H9M@2|Bacteria,4NXT6@976|Bacteroidetes,1IYX8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_5	929713.NIASO_03025	7.067e-68	234.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1ISGQ@117747|Sphingobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD1_k127_7689016_3	1123248.KB893318_gene4179	4.055e-160	508.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD1_k127_7689016_8	700598.Niako_5772	5.945e-22	99.0	COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_1	316274.Haur_2944	7.655e-176	558.0	COG1830@1|root,COG1830@2|Bacteria,2G8VI@200795|Chloroflexi	200795|Chloroflexi	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
HKD1_k127_7689016_2	1123248.KB893318_gene4181	9.312e-167	530.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1IPSH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7689016_4	700598.Niako_4523	2.99e-114	370.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
HKD1_k127_7691838_2	700598.Niako_5600	2.521e-62	220.0	COG0741@1|root,COG0741@2|Bacteria,4NEKW@976|Bacteroidetes,1IRNH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
HKD1_k127_7691838_4	700598.Niako_5601	3.487e-05	47.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1IPYM@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM chorismate binding	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD1_k127_7691838_1	1123248.KB893322_gene571	3.6e-221	691.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD1_k127_7691838_0	929713.NIASO_08415	4.318e-236	735.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
HKD1_k127_7710928_0	700598.Niako_1983	7.488e-146	464.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
HKD1_k127_7710928_2	925409.KI911562_gene1687	4.232e-07	51.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_7710928_1	700598.Niako_3506	1.643e-89	302.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
HKD1_k127_771813_3	925409.KI911562_gene1068	9.385e-93	309.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1IV58@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD1_k127_771813_5	1267211.KI669560_gene737	1.205e-60	211.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes	976|Bacteroidetes	Q	phenylacetic acid degradation protein	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
HKD1_k127_771813_2	700598.Niako_6200	3.073e-94	313.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1IVF8@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
HKD1_k127_771813_4	700598.Niako_4513	2.027e-82	289.0	2F5WP@1|root,33YFF@2|Bacteria,4P47E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_771813_1	1161401.ASJA01000006_gene1945	2.952e-100	339.0	COG0665@1|root,COG0665@2|Bacteria,1Q9VR@1224|Proteobacteria,2U05R@28211|Alphaproteobacteria,43X6E@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HKD1_k127_771813_0	1123057.P872_18840	4.051e-137	441.0	COG0322@1|root,COG0322@2|Bacteria,4NHBM@976|Bacteroidetes,47PDH@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF4357)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4357,GIY-YIG
HKD1_k127_771813_6	700598.Niako_6198	1.35e-55	195.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
HKD1_k127_7779030_2	700598.Niako_1201	1.106e-207	659.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_7779030_0	1123248.KB893314_gene3466	1.126e-307	952.0	COG0577@1|root,COG0577@2|Bacteria,4P243@976|Bacteroidetes,1IVV7@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_7779030_3	1121481.AUAS01000017_gene2497	4.05e-48	182.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47M2M@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_7779030_1	929556.Solca_0257	1.656e-214	681.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ8S@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_7788116_6	929713.NIASO_12265	9.931e-78	268.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD1_k127_7788116_7	1123248.KB893314_gene3431	1.095e-64	225.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7788116_0	700598.Niako_6875	1.648e-304	947.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD1_k127_7788116_2	929713.NIASO_12250	2.968e-198	626.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD1_k127_7788116_4	700598.Niako_6877	7.985e-104	343.0	COG0491@1|root,COG0491@2|Bacteria,4NHW8@976|Bacteroidetes,1IQ1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_7788116_8	755732.Fluta_1127	4.323e-59	220.0	COG0613@1|root,COG0613@2|Bacteria,4NTNF@976|Bacteroidetes	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7788116_3	1122176.KB903537_gene1695	2.258e-157	513.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IWP1@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HKD1_k127_7788116_1	700598.Niako_6842	1.732e-251	793.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1INX6@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
HKD1_k127_7788116_5	1122179.KB890423_gene2307	3.168e-92	325.0	COG2133@1|root,COG2133@2|Bacteria,4NH6T@976|Bacteroidetes,1IV5S@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
HKD1_k127_7788116_9	1007103.AFHW01000107_gene5189	9.207e-18	98.0	COG3325@1|root,COG4733@1|root,COG3325@2|Bacteria,COG4733@2|Bacteria,1UPJ7@1239|Firmicutes,4HBA7@91061|Bacilli,26SGN@186822|Paenibacillaceae	91061|Bacilli	G	chitinase	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,Glyco_hydro_18,Gram_pos_anchor,fn3
HKD1_k127_7796177_5	700598.Niako_5539	2.444e-76	270.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	5_nucleotid_C,HemolysinCabind,Laminin_G_3,VCBS
HKD1_k127_7796177_0	700598.Niako_0430	4.654e-152	491.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
HKD1_k127_7796177_6	1267211.KI669560_gene1008	3.316e-75	265.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes	976|Bacteroidetes	S	phosphotransferase enzyme family	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
HKD1_k127_7796177_1	929713.NIASO_04780	4.376e-149	481.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HKD1_k127_7796177_4	468059.AUHA01000003_gene1535	1.243e-110	367.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HKD1_k127_7796177_2	700598.Niako_1533	4.367e-147	472.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1IXEE@117747|Sphingobacteriia	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
HKD1_k127_7796177_3	700598.Niako_1532	2.175e-115	376.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD1_k127_7814010_1	925409.KI911562_gene1379	4.697e-210	664.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IUT7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
HKD1_k127_7814010_0	760192.Halhy_0774	4.555e-215	676.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IRDK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_7814010_2	1123248.KB893316_gene4597	2.563e-13	78.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
HKD1_k127_7815485_1	1123248.KB893316_gene4665	6.942e-81	273.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD1_k127_7815485_0	1123248.KB893316_gene4664	1.791e-125	413.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_7815485_2	1121904.ARBP01000002_gene6768	1.015e-21	96.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_7839165_9	1123248.KB893315_gene3092	2.434e-37	145.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1IR65@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
HKD1_k127_7839165_4	1123248.KB893315_gene3091	4.131e-69	241.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1IS9H@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_7839165_1	1267211.KI669560_gene610	3.703e-108	357.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_7839165_0	929713.NIASO_06925	4.857e-241	748.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
HKD1_k127_7839165_7	1185876.BN8_01658	3.524e-44	165.0	COG2318@1|root,COG2318@2|Bacteria,4NT5D@976|Bacteroidetes,47VVD@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
HKD1_k127_7839165_6	485918.Cpin_5229	1.735e-44	166.0	COG1051@1|root,COG1051@2|Bacteria,4NSYC@976|Bacteroidetes,1IXYT@117747|Sphingobacteriia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,NUDIX
HKD1_k127_7839165_3	700598.Niako_4477	1.09e-73	251.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD1_k127_7839165_2	1453498.LG45_07025	3.893e-83	288.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2NSRP@237|Flavobacterium	976|Bacteroidetes	E	aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_7839165_8	1123248.KB893314_gene3699	6.317e-38	146.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7839165_5	558152.IQ37_04825	7.439e-63	218.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia,3ZTB1@59732|Chryseobacterium	976|Bacteroidetes	S	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
HKD1_k127_7847274_6	1123248.KB893318_gene4242	7.858e-25	103.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1IQ3D@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HKD1_k127_7847274_1	1122605.KB893647_gene437	6.204e-110	357.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HKD1_k127_7847274_2	700598.Niako_4458	9.116e-66	227.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1ISSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HKD1_k127_7847274_3	1122605.KB893647_gene435	6e-63	217.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HKD1_k127_7847274_7	216432.CA2559_05830	5.47e-15	75.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HKD1_k127_7847274_5	700598.Niako_4461	1.437e-37	141.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HKD1_k127_7847274_0	700598.Niako_4468	4.943e-177	561.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
HKD1_k127_7851703_8	1237149.C900_03685	0.0006183	48.0	COG5002@1|root,COG5002@2|Bacteria,4PKMH@976|Bacteroidetes,47XWJ@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_9,TPR_12
HKD1_k127_7851703_0	700598.Niako_2627	0.0	1287.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia	976|Bacteroidetes	J	elongation factor G domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD1_k127_7851703_1	1122605.KB893637_gene3056	3.191e-300	933.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD1_k127_7851703_6	1122176.KB903542_gene389	1.309e-49	182.0	COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes	976|Bacteroidetes	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HKD1_k127_7851703_5	929713.NIASO_09670	7.01e-56	198.0	2DS2G@1|root,33E7Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7851703_2	1123248.KB893316_gene4532	7.441e-105	347.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1J0JU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
HKD1_k127_7851703_3	925409.KI911562_gene2046	4.241e-95	316.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD1_k127_7851703_4	700598.Niako_2634	5.331e-75	261.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1IQ5D@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD1_k127_7854851_4	595460.RRSWK_02095	1.039e-142	459.0	COG4146@1|root,COG4146@2|Bacteria,2J29I@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
HKD1_k127_7854851_1	925409.KI911562_gene1368	1.638e-199	626.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1IW5I@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
HKD1_k127_7854851_3	700598.Niako_0793	1.87e-155	498.0	COG3552@1|root,COG3552@2|Bacteria,4NKWF@976|Bacteroidetes,1IW0S@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
HKD1_k127_7854851_2	700598.Niako_0794	3.356e-160	507.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW0P@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ATPase associated with various cellular activities AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HKD1_k127_7854851_5	700598.Niako_0795	6.56e-124	402.0	COG1319@1|root,COG1319@2|Bacteria,4NE3W@976|Bacteroidetes,1IUZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HKD1_k127_7854851_0	700598.Niako_0796	0.0	1412.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IV5J@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HKD1_k127_7854851_6	700598.Niako_0797	2.724e-77	261.0	COG2080@1|root,COG2080@2|Bacteria,4NPUP@976|Bacteroidetes,1IX8R@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_7859765_8	700598.Niako_7222	2.873e-18	85.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7859765_2	700598.Niako_7221	1.899e-196	622.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
HKD1_k127_7859765_1	700598.Niako_7220	2.078e-231	724.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IR24@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
HKD1_k127_7859765_0	700598.Niako_7219	8.061e-275	859.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQWT@117747|Sphingobacteriia	976|Bacteroidetes	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
HKD1_k127_7859765_7	700598.Niako_7218	6.706e-46	168.0	COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,1ITB0@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
HKD1_k127_7859765_6	700598.Niako_7217	2.353e-59	212.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
HKD1_k127_7859765_5	700598.Niako_7216	8.589e-74	250.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
HKD1_k127_7859765_3	700598.Niako_7215	5.634e-176	557.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
HKD1_k127_7859765_4	700598.Niako_7214	2.519e-131	421.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
HKD1_k127_7864278_0	1237149.C900_00263	8.076e-80	295.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
HKD1_k127_7864278_1	929713.NIASO_00465	3.133e-67	232.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
HKD1_k127_7869658_0	1267211.KI669560_gene2806	1.055e-89	302.0	COG1131@1|root,COG1131@2|Bacteria,4NPDD@976|Bacteroidetes,1J1AC@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_7869658_1	700598.Niako_6916	1.427e-79	274.0	COG1277@1|root,COG1277@2|Bacteria,4NICG@976|Bacteroidetes	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD1_k127_7879462_4	1122605.KB893646_gene229	4.398e-73	247.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
HKD1_k127_7879462_3	700598.Niako_6938	7.195e-77	268.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD1_k127_7879462_5	700598.Niako_6937	2.671e-24	104.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1IUJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
HKD1_k127_7879462_1	1122605.KB893646_gene227	2.162e-116	381.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD1_k127_7879462_0	1123248.KB893317_gene4379	1.985e-152	494.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
HKD1_k127_7879462_2	714943.Mucpa_4435	9.006e-89	295.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_7898629_3	1408473.JHXO01000009_gene3380	5.579e-27	116.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,2G2VP@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD1_k127_7898629_1	1233951.IO90_14950	1.986e-47	176.0	COG2972@1|root,COG2972@2|Bacteria,4NMDQ@976|Bacteroidetes,1I1GC@117743|Flavobacteriia,3HIM7@358033|Chryseobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HKD1_k127_7898629_0	1408473.JHXO01000009_gene3381	1.167e-78	271.0	COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_7898629_2	1122179.KB890417_gene3261	5.52e-42	165.0	COG2353@1|root,COG2885@1|root,COG2353@2|Bacteria,COG2885@2|Bacteria,4PPP4@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_79016_0	929713.NIASO_14935	5.819e-218	685.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD1_k127_79016_1	700598.Niako_6087	4.776e-54	199.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IXCQ@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
HKD1_k127_7904738_1	1492737.FEM08_31290	2.567e-94	313.0	COG4313@1|root,COG4313@2|Bacteria,4NS24@976|Bacteroidetes,1I03V@117743|Flavobacteriia,2NVIW@237|Flavobacterium	976|Bacteroidetes	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
HKD1_k127_7904738_2	1008457.BAEX01000101_gene2216	5.734e-33	134.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia,47I43@76831|Myroides	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
HKD1_k127_7904738_0	1239962.C943_03737	9.531e-185	587.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HKD1_k127_7916898_1	700598.Niako_3912	4.284e-47	171.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1IPYC@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, deoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HKD1_k127_7916898_0	925409.KI911562_gene1256	0.0	1410.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IP91@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
HKD1_k127_7930828_0	1122605.KB893626_gene2711	6.901e-155	498.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD1_k127_7930828_1	700598.Niako_6638	3.073e-144	466.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
HKD1_k127_79501_1	5932.XP_004027511.1	4.013e-15	86.0	COG5253@1|root,KOG0229@2759|Eukaryota	2759|Eukaryota	T	1-phosphatidylinositol-4-phosphate 5-kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
HKD1_k127_79501_0	700598.Niako_0164	0.0	1414.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD1_k127_7964761_1	700598.Niako_7018	3.18e-88	300.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1ISN6@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
HKD1_k127_7964761_0	1123234.AUKI01000011_gene1518	1.809e-215	679.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD1_k127_7964761_2	1089547.KB913013_gene2212	6.038e-84	286.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
HKD1_k127_7964761_3	1358423.N180_02300	1.601e-28	119.0	2C56J@1|root,32YX8@2|Bacteria,4NW78@976|Bacteroidetes,1IYEC@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7979828_1	700598.Niako_5052	2.889e-151	482.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,1INRW@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
HKD1_k127_7979828_0	1396141.BATP01000056_gene3259	3.587e-167	552.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
HKD1_k127_7979828_2	1123248.KB893386_gene1948	4.117e-58	205.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HKD1_k127_7980733_0	925409.KI911562_gene2348	8.653e-153	488.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD1_k127_7980733_1	1123248.KB893330_gene407	1.117e-132	437.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD1_k127_7982122_2	1122605.KB893644_gene1349	1.869e-67	237.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ITT6@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
HKD1_k127_7982122_4	700598.Niako_7015	7.664e-39	148.0	2EC7G@1|root,33661@2|Bacteria,4NWXP@976|Bacteroidetes,1IU01@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4288
HKD1_k127_7982122_1	1122605.KB893644_gene1350	3.5e-98	332.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,1INSV@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD1_k127_7982122_0	1122605.KB893644_gene1351	7.233e-107	351.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_7982122_3	1239962.C943_01101	5.806e-51	190.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47N98@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
HKD1_k127_7984912_1	1123248.KB893337_gene2542	1.238e-50	183.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HKD1_k127_7984912_0	153721.MYP_4380	1.23e-177	561.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	yhbW	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
HKD1_k127_7996084_2	485918.Cpin_5483	3.93e-08	58.0	2EINM@1|root,33CE0@2|Bacteria,4NZKA@976|Bacteroidetes,1IUJW@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7996084_1	700598.Niako_0940	3.852e-72	247.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1ITJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HKD1_k127_7996084_0	929713.NIASO_02200	0.0	1110.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
HKD1_k127_800234_0	925409.KI911562_gene249	9.31e-178	570.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IUW9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
HKD1_k127_800234_1	925409.KI911562_gene248	3.423e-119	385.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD1_k127_800234_2	700598.Niako_5824	1.118e-98	327.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IWJZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_800234_3	925409.KI911562_gene2128	1.94e-08	59.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_835184_0	700598.Niako_6901	9.678e-264	823.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
HKD1_k127_835184_2	929562.Emtol_1444	2.275e-112	372.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,47NU5@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
HKD1_k127_83600_1	700598.Niako_5680	6.573e-264	823.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,1IPN6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HKD1_k127_83600_3	925409.KI911562_gene281	2.376e-82	286.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1IPUT@117747|Sphingobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_83600_5	700598.Niako_6868	1.455e-57	203.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
HKD1_k127_83600_0	700598.Niako_6867	4.464e-279	861.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes	976|Bacteroidetes	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD1_k127_83600_2	1122605.KB893647_gene376	1.47e-87	291.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1IS18@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HKD1_k127_83600_4	1122605.KB893647_gene426	5.915e-73	248.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_839808_2	1123248.KB893385_gene4847	5e-39	146.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
HKD1_k127_839808_0	1122605.KB893649_gene3825	3.555e-140	452.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1IP1D@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD1_k127_839808_1	700598.Niako_0116	3.831e-79	268.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
HKD1_k127_840755_5	1121373.KB903620_gene2104	3.723e-39	147.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,47JXN@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	xylR	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
HKD1_k127_840755_2	468059.AUHA01000002_gene1279	8.261e-56	197.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,1IXZD@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
HKD1_k127_840755_1	761193.Runsl_1328	2.527e-69	239.0	COG0262@1|root,COG0262@2|Bacteria,4NJIQ@976|Bacteroidetes,47PHT@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
HKD1_k127_840755_4	1266925.JHVX01000002_gene1045	5.888e-43	160.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2VUKU@28216|Betaproteobacteria,373FF@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
HKD1_k127_840755_0	700598.Niako_2154	4.972e-170	536.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
HKD1_k127_840755_3	485918.Cpin_1965	3.086e-45	168.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_883557_0	700598.Niako_6679	5.177e-237	741.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,1IV8P@117747|Sphingobacteriia	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
HKD1_k127_883557_1	1267211.KI669560_gene61	3.084e-169	537.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
HKD1_k127_90093_0	1121097.JCM15093_1927	1.781e-111	378.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,2FMC1@200643|Bacteroidia,4AKDR@815|Bacteroidaceae	976|Bacteroidetes	G	COG NOG04984 non supervised orthologous group	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
HKD1_k127_90093_1	1379698.RBG1_1C00001G0251	3.655e-61	220.0	2DEGI@1|root,2ZMXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_933723_0	700598.Niako_5041	0.0	1029.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
HKD1_k127_933723_1	700598.Niako_4282	3.194e-95	328.0	COG1520@1|root,COG1520@2|Bacteria,4NZRS@976|Bacteroidetes	2|Bacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,SLH,SprB,VCBS
HKD1_k127_933723_2	1183438.GKIL_0413	6.85e-17	87.0	COG2911@1|root,COG5295@1|root,COG2911@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	CBM_3,CHAT,CHU_C,Cohesin,Peptidase_S74
HKD1_k127_96471_5	485918.Cpin_5597	1.833e-110	368.0	COG2972@1|root,COG2972@2|Bacteria,4NHM5@976|Bacteroidetes,1IRRM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
HKD1_k127_96471_6	485918.Cpin_5598	2.745e-104	344.0	COG3279@1|root,COG3279@2|Bacteria,4NMI7@976|Bacteroidetes,1IRWQ@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_96471_8	700598.Niako_7024	1.8e-42	165.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1IZ7F@117747|Sphingobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
HKD1_k127_96471_0	925409.KI911562_gene970	1.9e-321	1009.0	COG1629@1|root,COG4771@2|Bacteria,4NJBC@976|Bacteroidetes,1J04Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
HKD1_k127_96471_9	714943.Mucpa_3010	1.03e-13	81.0	2DQ4P@1|root,334QK@2|Bacteria,4NVS1@976|Bacteroidetes,1IU46@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_96471_7	398720.MED217_09095	9.377e-46	175.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,1IIWC@117743|Flavobacteriia,2XK96@283735|Leeuwenhoekiella	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
HKD1_k127_96471_1	700598.Niako_0825	2.824e-308	963.0	COG1361@1|root,COG1472@1|root,COG1361@2|Bacteria,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IR7S@117747|Sphingobacteriia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HKD1_k127_96471_2	925409.KI911562_gene1594	1.076e-299	929.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IVNE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Glyco_hydro_3,Glyco_hydro_3_C,fn3
HKD1_k127_96471_3	1123248.KB893319_gene4021	1.611e-245	768.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1IRFR@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
HKD1_k127_96471_4	1267211.KI669560_gene463	2.979e-210	666.0	COG0657@1|root,COG4099@1|root,COG0657@2|Bacteria,COG4099@2|Bacteria,4PKKH@976|Bacteroidetes,1J0WF@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
HKD1_k127_977810_5	1123276.KB893290_gene5263	3.116e-07	53.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47NJB@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
HKD1_k127_977810_3	700598.Niako_2575	1.774e-194	610.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
HKD1_k127_977810_1	1047013.AQSP01000142_gene192	6.524e-234	747.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
HKD1_k127_977810_0	700598.Niako_2576	3.819e-251	781.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1INQK@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD1_k127_977810_2	1123248.KB893337_gene2535	3.496e-210	661.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,1IRPS@117747|Sphingobacteriia	976|Bacteroidetes	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
HKD1_k127_977810_4	925409.KI911562_gene2711	1.696e-63	219.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD1_k127_984289_2	1408473.JHXO01000010_gene3519	7.452e-25	111.0	COG2856@1|root,COG2856@2|Bacteria,4NN24@976|Bacteroidetes,2FV5Y@200643|Bacteroidia	976|Bacteroidetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_984289_0	1239962.C943_01704	4.067e-66	238.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
HKD1_k127_984289_1	1094466.KQS_03790	9.176e-27	109.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia,2NTI9@237|Flavobacterium	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD1_k127_98507_3	1123248.KB893329_gene4467	1.626e-23	101.0	COG1957@1|root,COG1957@2|Bacteria,4NH09@976|Bacteroidetes,1IRUK@117747|Sphingobacteriia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
HKD1_k127_98507_1	925409.KI911562_gene2375	1.252e-142	457.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
HKD1_k127_98507_2	700598.Niako_4562	2.784e-84	286.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1J0TI@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
HKD1_k127_98507_0	1123248.KB893315_gene3149	5.576e-196	615.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
## 3290 queries scanned
## Total time (seconds): 183.3958785533905
## Rate: 17.94 q/s