## Fri Nov 15 21:56:50 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin8/HKD_1_bin.82.fa -m mmseqs --itype genome -o HKD_1_bin.82 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/HKD_1_bin.82 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HKD1_k127_1009787_0	1476973.JMMB01000004_gene3418	1.242e-236	741.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,25SWU@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_1009787_3	1476973.JMMB01000004_gene3417	5.476e-137	437.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25QH7@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1009787_18	1410625.JHWK01000002_gene303	3.969e-08	56.0	2A6R2@1|root,30VJ6@2|Bacteria,1U3U1@1239|Firmicutes,254V2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1009787_1	1391646.AVSU01000061_gene1058	5.065e-192	609.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
HKD1_k127_1009787_14	1391646.AVSU01000129_gene2720	4.198e-19	89.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2,SH3_3,SPOR
HKD1_k127_1009787_9	1391646.AVSU01000126_gene2195	1.264e-31	125.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,24PSJ@186801|Clostridia	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
HKD1_k127_1009787_21	1391646.AVSU01000126_gene2195	0.0009726	42.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,24PSJ@186801|Clostridia	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
HKD1_k127_1009787_4	33035.JPJF01000019_gene4305	9.976e-126	406.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
HKD1_k127_1009787_10	1292035.H476_1504	9.929e-30	119.0	2C3GY@1|root,332NU@2|Bacteria,1UPV8@1239|Firmicutes,24QHE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1009787_6	1391646.AVSU01000019_gene1321	3.046e-50	180.0	COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,25N2P@186801|Clostridia,25TGE@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD1_k127_1009787_7	1391646.AVSU01000019_gene1322	4.051e-33	138.0	2DZ0W@1|root,34C2B@2|Bacteria,1VZKG@1239|Firmicutes,24QXF@186801|Clostridia,25RXX@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1009787_15	1476973.JMMB01000001_gene3354	9.395e-15	75.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JM4@186801|Clostridia,25TZ3@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_1009787_19	999411.HMPREF1092_02069	1.007e-06	54.0	2A64A@1|root,30UWS@2|Bacteria,1UQMI@1239|Firmicutes,24UD0@186801|Clostridia,36MM0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1009787_2	1391646.AVSU01000126_gene2195	7.991e-185	583.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,24PSJ@186801|Clostridia	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
HKD1_k127_1009787_13	1391646.AVSU01000127_gene2183	2.775e-20	93.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,25JZH@186801|Clostridia,25U05@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_1009787_8	1476973.JMMB01000005_gene3469	9.082e-33	127.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JM4@186801|Clostridia,25TZ3@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_1141683_57	1476973.JMMB01000007_gene401	6.776e-111	362.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25R40@186804|Peptostreptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD1_k127_1141683_23	1476973.JMMB01000007_gene402	5.905e-194	608.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25QGI@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_1141683_2	1476973.JMMB01000007_gene403	0.0	1284.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,25QRG@186804|Peptostreptococcaceae	186801|Clostridia	K	Tex-like protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HKD1_k127_1141683_16	1476973.JMMB01000007_gene404	1.636e-239	741.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,25R60@186804|Peptostreptococcaceae	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_1141683_60	1476973.JMMB01000007_gene405	3.067e-101	333.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,25RG0@186804|Peptostreptococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HKD1_k127_1141683_87	1476973.JMMB01000007_gene2301	1.251e-25	109.0	2BE2M@1|root,327TA@2|Bacteria,1UTQ3@1239|Firmicutes,253W0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_65	1476973.JMMB01000007_gene406	2.475e-85	283.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25RB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HKD1_k127_1141683_43	1476973.JMMB01000007_gene407	2.6e-138	441.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25QHX@186804|Peptostreptococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
HKD1_k127_1141683_77	1219626.HMPREF1639_05090	5.062e-53	190.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25RIP@186804|Peptostreptococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
HKD1_k127_1141683_21	1476973.JMMB01000007_gene409	3.602e-201	628.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,25QD9@186804|Peptostreptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD1_k127_1141683_15	1476973.JMMB01000007_gene419	1.105e-249	775.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,25S47@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_1141683_4	1476973.JMMB01000007_gene418	0.0	1140.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25R5G@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD1_k127_1141683_52	1476973.JMMB01000007_gene417	4.727e-122	393.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25R18@186804|Peptostreptococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HKD1_k127_1141683_86	1301100.HG529422_gene4238	2.084e-29	117.0	COG2221@1|root,COG2221@2|Bacteria,1UHV8@1239|Firmicutes,25E3Z@186801|Clostridia,36UHN@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HKD1_k127_1141683_40	1391646.AVSU01000128_gene2425	1.86e-144	468.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,25TUS@186804|Peptostreptococcaceae	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap,Peptidase_M15
HKD1_k127_1141683_3	1476973.JMMB01000007_gene421	0.0	1193.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25R7I@186804|Peptostreptococcaceae	186801|Clostridia	C	Prismane/CO dehydrogenase family	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04490	Prismane
HKD1_k127_1141683_48	1476973.JMMB01000007_gene426	3.738e-127	411.0	COG1302@1|root,COG1302@2|Bacteria,1V1TU@1239|Firmicutes,24E60@186801|Clostridia,25STZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Asp23,IPT
HKD1_k127_1141683_12	1476973.JMMB01000007_gene425	3.986e-277	853.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,25QK8@186804|Peptostreptococcaceae	186801|Clostridia	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gluD	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD1_k127_1141683_32	1476973.JMMB01000007_gene427	1.084e-175	558.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,25ST5@186804|Peptostreptococcaceae	186801|Clostridia	M	Src homology 3 domains	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CW_binding_2,NLPC_P60,SH3_3
HKD1_k127_1141683_26	1476973.JMMB01000007_gene428	1.016e-188	592.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,25QS8@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
HKD1_k127_1141683_49	500633.CLOHIR_00049	6.169e-127	407.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,25QJ7@186804|Peptostreptococcaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iHN637.CLJU_RS17580	DHODB_Fe-S_bind,NAD_binding_1
HKD1_k127_1141683_29	1476973.JMMB01000007_gene430	2.192e-183	574.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25QCB@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HKD1_k127_1141683_56	1301100.HG529423_gene1978	1.181e-117	380.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,36FPJ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HKD1_k127_1141683_69	1391646.AVSU01000031_gene2567	1.275e-69	239.0	COG0716@1|root,COG0716@2|Bacteria,1VBEZ@1239|Firmicutes,24JJ6@186801|Clostridia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4,Flavodoxin_5
HKD1_k127_1141683_39	1476973.JMMB01000007_gene432	3.601e-145	464.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,25C6S@186801|Clostridia,25SDD@186804|Peptostreptococcaceae	186801|Clostridia	K	LysR substrate binding domain	cysL	-	-	ko:K21900	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HKD1_k127_1141683_34	1301100.HG529423_gene1980	4.313e-166	527.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,36E0G@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
HKD1_k127_1141683_44	1476973.JMMB01000007_gene434	2.184e-133	426.0	COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,24B8K@186801|Clostridia,25S14@186804|Peptostreptococcaceae	186801|Clostridia	F	Deoxynucleoside kinase	-	-	2.7.1.74,2.7.1.76	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R00185,R01666,R02089	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
HKD1_k127_1141683_46	1476973.JMMB01000007_gene435	4.829e-128	410.0	COG1428@1|root,COG1428@2|Bacteria,1TQKS@1239|Firmicutes,24XJD@186801|Clostridia,25S8G@186804|Peptostreptococcaceae	186801|Clostridia	F	Deoxynucleoside kinase	-	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
HKD1_k127_1141683_30	1301100.HG529424_gene1984	1.135e-178	561.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,36DTH@31979|Clostridiaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
HKD1_k127_1141683_24	1035196.HMPREF9998_01515	3.265e-192	611.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25QFN@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD1_k127_1141683_79	1476973.JMMB01000007_gene438	1.351e-49	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25RM6@186804|Peptostreptococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HKD1_k127_1141683_8	1476973.JMMB01000007_gene439	2.737e-321	987.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,25QTW@186804|Peptostreptococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HKD1_k127_1141683_84	431943.CKL_2147	5.233e-32	130.0	COG0264@1|root,COG0264@2|Bacteria,1VGFM@1239|Firmicutes,24JNW@186801|Clostridia,36W3M@31979|Clostridiaceae	186801|Clostridia	J	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
HKD1_k127_1141683_64	1487921.DP68_17130	4.396e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,36EJ3@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	arlR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1141683_54	748727.CLJU_c17320	2.259e-118	391.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,36EDC@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_1141683_41	1476973.JMMB01000007_gene443	9.958e-143	454.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,25QT3@186804|Peptostreptococcaceae	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
HKD1_k127_1141683_45	1301100.HG529424_gene1989	4.109e-128	413.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,36DW1@31979|Clostridiaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
HKD1_k127_1141683_68	1476973.JMMB01000007_gene446	3.779e-70	240.0	COG1641@1|root,COG1641@2|Bacteria,1V4CM@1239|Firmicutes,24Q1I@186801|Clostridia,25RJ9@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
HKD1_k127_1141683_10	1476973.JMMB01000007_gene447	5.673e-294	906.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,25QVZ@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
HKD1_k127_1141683_7	1476973.JMMB01000007_gene448	1e-323	991.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,25QVV@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
HKD1_k127_1141683_19	1476973.JMMB01000007_gene449	9.019e-223	697.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25SX3@186804|Peptostreptococcaceae	186801|Clostridia	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD1_k127_1141683_31	1476973.JMMB01000007_gene450	5.451e-178	561.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,25S1Q@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HKD1_k127_1141683_18	1476973.JMMB01000007_gene451	5.865e-225	703.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25R1F@186804|Peptostreptococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD1_k127_1141683_67	1476973.JMMB01000007_gene453	3.411e-80	269.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,25RCN@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HKD1_k127_1141683_42	1476973.JMMB01000007_gene454	3.254e-139	443.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,25RAA@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HKD1_k127_1141683_14	1301100.HG529426_gene1998	2.275e-271	837.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,36ECS@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HKD1_k127_1141683_20	1301100.HG529426_gene1999	4.636e-208	649.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,36F1W@31979|Clostridiaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HKD1_k127_1141683_71	1209989.TepiRe1_1178	2.276e-68	237.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,42GE6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
HKD1_k127_1141683_9	1476973.JMMB01000007_gene458	3.583e-309	949.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,25QUK@186804|Peptostreptococcaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
HKD1_k127_1141683_17	1476973.JMMB01000007_gene459	5.121e-236	734.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25R7Z@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HKD1_k127_1141683_0	86416.Clopa_2050	0.0	1592.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,36UJE@31979|Clostridiaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HKD1_k127_1141683_36	1292035.H476_1163	3.305e-165	522.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25SIH@186804|Peptostreptococcaceae	186801|Clostridia	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
HKD1_k127_1141683_90	1286171.EAL2_808p00380	5.994e-12	69.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,25VGM@186806|Eubacteriaceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
HKD1_k127_1141683_89	1216932.CM240_0115	6.323e-17	81.0	COG3209@1|root,COG3227@1|root,COG4926@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3227@2|Bacteria,COG4926@2|Bacteria,COG5492@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36GGX@31979|Clostridiaceae	186801|Clostridia	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,RicinB_lectin_2
HKD1_k127_1141683_5	1476973.JMMB01000007_gene463	0.0	1111.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,25QGB@186804|Peptostreptococcaceae	186801|Clostridia	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
HKD1_k127_1141683_88	1476973.JMMB01000007_gene1532	3.737e-21	94.0	29X3F@1|root,30IS4@2|Bacteria,1TY6N@1239|Firmicutes,24UE9@186801|Clostridia,25U6R@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3955)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3955
HKD1_k127_1141683_83	1499689.CCNN01000007_gene914	2.868e-34	132.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,36KI4@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
HKD1_k127_1141683_73	1292035.H476_0151	6.552e-61	214.0	2BRA3@1|root,32K8M@2|Bacteria,1URR9@1239|Firmicutes,24WIG@186801|Clostridia,25TYC@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
HKD1_k127_1141683_47	1476973.JMMB01000007_gene466	2.18e-127	412.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia,25S1B@186804|Peptostreptococcaceae	186801|Clostridia	K	TipAS antibiotic-recognition domain	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
HKD1_k127_1141683_61	1301100.HG529332_gene4565	4.031e-101	334.0	2DCPZ@1|root,2ZEW4@2|Bacteria,1V1NN@1239|Firmicutes,24FYM@186801|Clostridia,36J2S@31979|Clostridiaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HKD1_k127_1141683_53	1476973.JMMB01000007_gene472	9.893e-121	390.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,25S6C@186804|Peptostreptococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1141683_28	1476973.JMMB01000007_gene473	6.632e-184	584.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25T32@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_1141683_62	1235799.C818_00644	5.249e-100	330.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27KMJ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_1141683_6	1476973.JMMB01000007_gene475	0.0	1032.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,25SV7@186804|Peptostreptococcaceae	186801|Clostridia	MV	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD1_k127_1141683_33	1151292.QEW_0772	5.214e-175	563.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
HKD1_k127_1141683_58	1301100.HG529409_gene183	1.414e-106	351.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,36FG9@31979|Clostridiaceae	186801|Clostridia	KT	transcriptional regulatory protein	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1141683_82	1391646.AVSU01000079_gene2888	8.36e-36	139.0	COG4785@1|root,COG4785@2|Bacteria	2|Bacteria	S	cell division	nlpI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_8
HKD1_k127_1141683_74	1476973.JMMB01000007_gene2516	4.757e-60	211.0	COG0569@1|root,COG0569@2|Bacteria,1V2ZF@1239|Firmicutes,24GNX@186801|Clostridia	186801|Clostridia	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
HKD1_k127_1141683_50	1476973.JMMB01000007_gene2515	2.26e-123	398.0	COG0569@1|root,COG0569@2|Bacteria,1W73F@1239|Firmicutes,25M93@186801|Clostridia,25U88@186804|Peptostreptococcaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
HKD1_k127_1141683_11	1476973.JMMB01000007_gene2513	1.35e-279	864.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,25QXK@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD1_k127_1141683_85	1499689.CCNN01000014_gene3137	7.581e-32	130.0	2EDRU@1|root,337MD@2|Bacteria,1VIEE@1239|Firmicutes,24P45@186801|Clostridia,36KTK@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_92	1301100.HG529409_gene180	5.307e-06	51.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,36E52@31979|Clostridiaceae	186801|Clostridia	P	potassium uptake protein TrkH	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD1_k127_1141683_80	1476973.JMMB01000007_gene476	1.852e-41	153.0	2BME2@1|root,32FYI@2|Bacteria,1UF3C@1239|Firmicutes,25K45@186801|Clostridia,25UB8@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal L25p family	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p
HKD1_k127_1141683_25	1292035.H476_1350	4.968e-189	593.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia,25T0N@186804|Peptostreptococcaceae	186801|Clostridia	L	Spore photoproduct lyase	splB	GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0016829,GO:0016830,GO:0043167,GO:0043169,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0070283,GO:0140097	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
HKD1_k127_1141683_81	1301100.HG529426_gene2010	3.895e-37	141.0	2FDHM@1|root,345J3@2|Bacteria,1VZHH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_38	1151292.QEW_0469	4.309e-150	480.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
HKD1_k127_1141683_59	1476973.JMMB01000007_gene482	1.476e-105	347.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
HKD1_k127_1141683_13	1476973.JMMB01000007_gene483	5.809e-275	848.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,25R04@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_1141683_66	1476973.JMMB01000007_gene484	3.493e-83	278.0	29FSB@1|root,302Q0@2|Bacteria,1V4FR@1239|Firmicutes,24KTG@186801|Clostridia,25T8J@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_55	1476973.JMMB01000007_gene485	3.49e-118	384.0	COG1424@1|root,COG1424@2|Bacteria,1V38Y@1239|Firmicutes,24HW2@186801|Clostridia,25T61@186804|Peptostreptococcaceae	186801|Clostridia	H	6-carboxyhexanoate--CoA ligase	bioW	-	6.2.1.14	ko:K01906	ko00780,ko01100,map00780,map01100	M00577	R03209	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	BioW
HKD1_k127_1141683_27	1476973.JMMB01000007_gene486	5.466e-188	592.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,25SGT@186804|Peptostreptococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	bioF	-	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,BioW
HKD1_k127_1141683_93	1121333.JMLH01000058_gene1726	1.483e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,3VQE9@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
HKD1_k127_1141683_63	1301100.HG529227_gene5489	4.286e-96	325.0	COG3936@1|root,COG3936@2|Bacteria,1V4II@1239|Firmicutes,25ECE@186801|Clostridia,36UKA@31979|Clostridiaceae	186801|Clostridia	G	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_1141683_78	1292035.H476_0154	1.525e-50	184.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD1_k127_1141683_35	1301100.HG529426_gene2019	6.397e-166	523.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,36F6T@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_75	1408823.AXUS01000011_gene2013	1.05e-56	200.0	COG0484@1|root,COG0484@2|Bacteria,1V6FQ@1239|Firmicutes,24PF0@186801|Clostridia,25RNR@186804|Peptostreptococcaceae	186801|Clostridia	O	molecular chaperone DnaJ	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_70	1476973.JMMB01000007_gene489	2.509e-69	238.0	2DQ8Z@1|root,335CG@2|Bacteria,1V9R5@1239|Firmicutes,24JTW@186801|Clostridia,25RMX@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_37	1476973.JMMB01000007_gene490	1.312e-150	477.0	COG0560@1|root,COG0560@2|Bacteria,1UYZ6@1239|Firmicutes,24AC7@186801|Clostridia,25QBY@186804|Peptostreptococcaceae	186801|Clostridia	E	HAD hydrolase, family IB	serB	-	-	-	-	-	-	-	-	-	-	-	HAD
HKD1_k127_1141683_22	1476973.JMMB01000007_gene491	2.438e-200	627.0	2DKA9@1|root,32UEQ@2|Bacteria,1VE7Y@1239|Firmicutes,24KB2@186801|Clostridia,25R3C@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_76	1476973.JMMB01000007_gene492	3.568e-54	196.0	29UR2@1|root,30G31@2|Bacteria,1UF3T@1239|Firmicutes,253J6@186801|Clostridia,25UCJ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1141683_72	1476973.JMMB01000007_gene493	7.527e-66	226.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,25RHS@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD1_k127_1141683_1	1476973.JMMB01000007_gene494	0.0	1308.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,25QPH@186804|Peptostreptococcaceae	186801|Clostridia	P	Cadmium-exporting ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_1141683_51	1476973.JMMB01000007_gene495	6.802e-123	395.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,25R01@186804|Peptostreptococcaceae	186801|Clostridia	S	Channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
HKD1_k127_1155760_8	500633.CLOHIR_00532	2.08e-79	301.0	COG2247@1|root,COG2247@2|Bacteria,1VS6B@1239|Firmicutes	1239|Firmicutes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF5011
HKD1_k127_1155760_16	1552123.EP57_06130	8.097e-33	149.0	COG4932@1|root,COG4932@2|Bacteria,1VJGI@1239|Firmicutes,4ISKD@91061|Bacilli,26K0S@186820|Listeriaceae	91061|Bacilli	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Gram_pos_anchor,SdrD_B
HKD1_k127_1155760_14	313606.M23134_05450	1.07e-35	158.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,4NKMV@976|Bacteroidetes,47QYS@768503|Cytophagia	976|Bacteroidetes	AT	Leucine Rich repeat	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHAT,COR,LRR_4,LRR_6,Roc
HKD1_k127_1155760_10	697303.Thewi_2166	7.252e-55	200.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,24E64@186801|Clostridia,42I08@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,rve
HKD1_k127_1155760_17	1410633.JHWR01000008_gene1642	5.415e-30	128.0	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,24DKZ@186801|Clostridia	186801|Clostridia	L	IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD1_k127_1155760_19	555079.Toce_0191	4.187e-19	88.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
HKD1_k127_1155760_9	1443122.Z958_08445	7.564e-71	257.0	COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,24FG2@186801|Clostridia,36GWZ@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
HKD1_k127_1155760_13	1211817.CCAT010000043_gene3455	2.225e-36	144.0	COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,24KDK@186801|Clostridia,36JQ4@31979|Clostridiaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
HKD1_k127_1155760_12	632245.CLP_1382	1.103e-45	172.0	COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,24N8D@186801|Clostridia,36IJR@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
HKD1_k127_1155760_11	1476973.JMMB01000007_gene2448	2.013e-47	174.0	2FJ7H@1|root,34AXK@2|Bacteria,1W16C@1239|Firmicutes,24T9R@186801|Clostridia,25U98@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1155760_1	1476973.JMMB01000007_gene2449	1.323e-268	831.0	COG2897@1|root,COG2897@2|Bacteria,1TS7E@1239|Firmicutes,24CNW@186801|Clostridia,25SF2@186804|Peptostreptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.11	ko:K21028	ko04122,map04122	-	R07461	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD1_k127_1155760_5	195103.CPF_0503	3.584e-141	460.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia,36DWJ@31979|Clostridiaceae	186801|Clostridia	S	PTS system	ulaA	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
HKD1_k127_1155760_18	1385512.N784_05810	1.115e-22	100.0	COG3414@1|root,COG3414@2|Bacteria,1VBFW@1239|Firmicutes,4HKT5@91061|Bacilli,2YAUA@289201|Pontibacillus	91061|Bacilli	G	PTS lactose transporter subunit IIB	-	-	2.7.1.194	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_IIB
HKD1_k127_1155760_15	857293.CAAU_0126	1.974e-33	134.0	COG1762@1|root,COG1762@2|Bacteria,1V5JU@1239|Firmicutes,24Q73@186801|Clostridia,36V5N@31979|Clostridiaceae	186801|Clostridia	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_EIIA_2
HKD1_k127_1155760_6	1321778.HMPREF1982_04585	4.917e-136	447.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia,2682N@186813|unclassified Clostridiales	186801|Clostridia	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
HKD1_k127_1155760_7	720554.Clocl_2211	1.213e-79	271.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1155760_4	431943.CKL_1494	1.457e-142	466.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36EQ3@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_1155760_3	1151292.QEW_1251	2.826e-188	590.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,25QPS@186804|Peptostreptococcaceae	186801|Clostridia	C	Isocitrate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HKD1_k127_1155760_0	1151292.QEW_1250	0.0	1098.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25SZA@186804|Peptostreptococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HKD1_k127_1155760_2	500633.CLOHIR_01876	2.085e-206	646.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,25QU8@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	nifV	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
HKD1_k127_1158053_5	1292035.H476_2385	1.52e-83	280.0	COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,247MM@186801|Clostridia,25S6I@186804|Peptostreptococcaceae	186801|Clostridia	E	PHP domain	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HKD1_k127_1158053_1	1499689.CCNN01000014_gene3200	9.261e-183	575.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,36EB5@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HKD1_k127_1158053_7	1499689.CCNN01000014_gene3202	6.603e-73	248.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,36HJI@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HKD1_k127_1158053_4	1391646.AVSU01000025_gene2466	1.011e-93	315.0	2BDI8@1|root,3277G@2|Bacteria,1UT3E@1239|Firmicutes,2514X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1158053_9	1211817.CCAT010000047_gene2548	1.508e-65	227.0	COG1846@1|root,COG1846@2|Bacteria,1VBKN@1239|Firmicutes,24PC9@186801|Clostridia,36JM7@31979|Clostridiaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HKD1_k127_1158053_2	1123009.AUID01000011_gene2265	1.097e-164	524.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,2694Z@186813|unclassified Clostridiales	186801|Clostridia	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD1_k127_1158053_8	983328.AFGH01000042_gene12	6.053e-70	246.0	COG2184@1|root,COG2184@2|Bacteria,1NZK6@1224|Proteobacteria,42RBM@68525|delta/epsilon subdivisions,2YP1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HKD1_k127_1158053_3	1391646.AVSU01000016_gene3172	5.915e-151	486.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HKD1_k127_1158053_10	316274.Haur_2967	1.027e-07	58.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8VB@200795|Chloroflexi,375FX@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trans_reg_C
HKD1_k127_1158053_6	643648.Slip_1247	7.61e-77	282.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HKD1_k127_1158053_0	272563.CD630_20850	6.329e-214	669.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,25SHS@186804|Peptostreptococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
HKD1_k127_1177316_11	203119.Cthe_2647	1.037e-11	68.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD1_k127_1177316_9	203119.Cthe_2646	4.566e-40	163.0	COG0381@1|root,COG0381@2|Bacteria,1VZ2I@1239|Firmicutes	1239|Firmicutes	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HKD1_k127_1177316_12	1121289.JHVL01000013_gene1666	5.705e-05	55.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,36ERI@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
HKD1_k127_1177316_1	1196322.A370_05162	1.211e-172	558.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,36MH8@31979|Clostridiaceae	186801|Clostridia	E	Isopropylmalate homocitrate citramalate	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HKD1_k127_1177316_2	1196322.A370_05161	1.907e-122	396.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,36MAD@31979|Clostridiaceae	186801|Clostridia	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
HKD1_k127_1177316_6	1262449.CP6013_0259	1.153e-70	244.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase
HKD1_k127_1177316_8	1292035.H476_0626	2.839e-43	162.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia,25U32@186804|Peptostreptococcaceae	186801|Clostridia	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD1_k127_1177316_5	1476973.JMMB01000007_gene740	4.066e-74	254.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,25T9T@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_1177316_0	1292035.H476_2954	2.527e-266	829.0	COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,25EQS@186801|Clostridia	186801|Clostridia	E	Amino acid permease	-	-	-	ko:K03293,ko:K11733	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.2	-	iHN637.CLJU_RS10705	AA_permease
HKD1_k127_1177316_7	1151292.QEW_4269	5.387e-49	179.0	2DMWG@1|root,32U3S@2|Bacteria,1VA7F@1239|Firmicutes,24MP5@186801|Clostridia,25TFU@186804|Peptostreptococcaceae	186801|Clostridia	S	YmaF family	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
HKD1_k127_1177316_3	1391646.AVSU01000123_gene3345	3.828e-116	376.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,249E0@186801|Clostridia,25QW0@186804|Peptostreptococcaceae	186801|Clostridia	S	GPR1/FUN34/yaaH family	yaaH	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
HKD1_k127_1177316_10	140626.JHWB01000009_gene1768	5.332e-12	73.0	2FCB0@1|root,344EK@2|Bacteria,1W0ZW@1239|Firmicutes,2532J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1177316_4	1476973.JMMB01000007_gene312	2.914e-101	332.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes,24CPD@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD1_k127_1325190_1	1476973.JMMB01000007_gene1291	1.667e-208	651.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,25R0C@186804|Peptostreptococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HKD1_k127_1325190_2	1301100.HG529280_gene7017	8.185e-193	606.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,36F1U@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
HKD1_k127_1325190_3	1476973.JMMB01000007_gene1290	2.34e-181	570.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,25QC1@186804|Peptostreptococcaceae	186801|Clostridia	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HKD1_k127_1325190_0	1476973.JMMB01000007_gene1288	0.0	1031.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia,25R86@186804|Peptostreptococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,TPR_16,TPR_2,TPR_7,TPR_8
HKD1_k127_1325190_4	1476973.JMMB01000007_gene1287	1.834e-128	415.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,25RPX@186804|Peptostreptococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HKD1_k127_134157_25	1476973.JMMB01000007_gene402	3.202e-19	88.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25QGI@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_134157_0	1301100.HG529421_gene7069	0.0	1606.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,36DNR@31979|Clostridiaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HKD1_k127_134157_21	1476973.JMMB01000007_gene400	8.709e-91	301.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25RMW@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD1_k127_134157_17	1301100.HG529420_gene2930	1.02e-116	380.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HKD1_k127_134157_1	1476973.JMMB01000007_gene396	0.0	1382.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25QNC@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
HKD1_k127_134157_5	1476973.JMMB01000007_gene395	1.359e-241	749.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25QJU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD1_k127_134157_20	1476973.JMMB01000007_gene394	6.691e-95	312.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24FSH@186801|Clostridia,25S37@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1256)	yyaC	-	-	-	-	-	-	-	-	-	-	-	DUF1256
HKD1_k127_134157_22	1476973.JMMB01000007_gene393	9.691e-80	267.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,25RHK@186804|Peptostreptococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HKD1_k127_134157_8	1476973.JMMB01000007_gene392	7.076e-197	618.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25QKC@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD1_k127_134157_23	1476973.JMMB01000007_gene391	9.219e-49	174.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25TN7@186804|Peptostreptococcaceae	186801|Clostridia	K	Stage III sporulation protein D	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
HKD1_k127_134157_18	1476973.JMMB01000007_gene390	1.953e-107	351.0	COG0739@1|root,COG0739@2|Bacteria,1V96D@1239|Firmicutes,24AXE@186801|Clostridia,25RDJ@186804|Peptostreptococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HKD1_k127_134157_10	1476973.JMMB01000007_gene389	1.45e-170	540.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,25R0G@186804|Peptostreptococcaceae	186801|Clostridia	D	Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
HKD1_k127_134157_4	1476973.JMMB01000007_gene388	1.202e-252	781.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,25QQ8@186804|Peptostreptococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD1_k127_134157_16	1476973.JMMB01000007_gene387	1.637e-127	410.0	29RDG@1|root,30CFT@2|Bacteria,1V604@1239|Firmicutes,24J2B@186801|Clostridia,25RGK@186804|Peptostreptococcaceae	186801|Clostridia	S	TATA-box binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF1779
HKD1_k127_134157_12	1476973.JMMB01000007_gene386	2.963e-155	493.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,25SFZ@186804|Peptostreptococcaceae	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,NIR_SIR,NIR_SIR_ferr
HKD1_k127_134157_2	1476973.JMMB01000007_gene385	0.0	1168.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,25QFM@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HKD1_k127_134157_3	1301100.HG529419_gene3063	8.845e-272	839.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,36DMU@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_134157_19	1476973.JMMB01000007_gene383	4.57e-101	330.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,25RBE@186804|Peptostreptococcaceae	186801|Clostridia	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,Rubrerythrin
HKD1_k127_134157_11	1476973.JMMB01000007_gene382	2.874e-161	508.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,25QMV@186804|Peptostreptococcaceae	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD1_k127_134157_6	1476973.JMMB01000007_gene381	2.128e-224	696.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,25QKU@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
HKD1_k127_134157_24	1476973.JMMB01000007_gene380	4.127e-38	143.0	COG1143@1|root,COG1143@2|Bacteria,1UHZA@1239|Firmicutes,24QVY@186801|Clostridia,25RTY@186804|Peptostreptococcaceae	186801|Clostridia	C	binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
HKD1_k127_134157_15	1476973.JMMB01000007_gene379	7.995e-134	427.0	COG0455@1|root,COG0455@2|Bacteria,1V1FH@1239|Firmicutes,24DP7@186801|Clostridia,25R35@186804|Peptostreptococcaceae	186801|Clostridia	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
HKD1_k127_134157_7	1476973.JMMB01000007_gene378	1.87e-218	679.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,25QTD@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
HKD1_k127_134157_9	1476973.JMMB01000007_gene377	8.994e-179	561.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25RBP@186804|Peptostreptococcaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
HKD1_k127_134157_13	1476973.JMMB01000007_gene376	1.099e-151	488.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24FPH@186801|Clostridia,25RAE@186804|Peptostreptococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HKD1_k127_134157_14	1476973.JMMB01000007_gene375	6.139e-151	480.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,25R3R@186804|Peptostreptococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HKD1_k127_134157_28	1461580.CCAS010000015_gene1842	2.088e-07	55.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_134157_26	1408823.AXUS01000073_gene990	1.583e-12	68.0	2DR59@1|root,33A7S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_134157_29	411463.EUBVEN_00322	9.454e-07	51.0	2DEPA@1|root,2ZNPC@2|Bacteria,1W4IB@1239|Firmicutes,254JF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_134157_27	509191.AEDB02000028_gene2901	7.259e-08	53.0	2EFGV@1|root,3399G@2|Bacteria,1U5Y2@1239|Firmicutes,24WP5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_67	1301100.HG529348_gene4319	3.321e-162	516.0	COG3641@1|root,COG3641@2|Bacteria,1UNZM@1239|Firmicutes,24A9C@186801|Clostridia,36FU5@31979|Clostridiaceae	186801|Clostridia	S	Phosphotransferase system, EIIC	pfoR	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIC_2
HKD1_k127_1392218_187	1243664.CAVL020000055_gene2535	2.053e-09	58.0	29S7Z@1|root,30DCG@2|Bacteria,1UB50@1239|Firmicutes,4IMHI@91061|Bacilli,1ZK63@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_74	1476973.JMMB01000007_gene1213	2.139e-155	499.0	COG1357@1|root,COG1357@2|Bacteria,1VDTQ@1239|Firmicutes,24D3P@186801|Clostridia,25R0H@186804|Peptostreptococcaceae	186801|Clostridia	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_3,Pentapeptide_4
HKD1_k127_1392218_65	1151292.QEW_2071	2.157e-170	539.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,25QZT@186804|Peptostreptococcaceae	186801|Clostridia	H	Lipoate-protein ligase	lplJ	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD1_k127_1392218_14	1476973.JMMB01000007_gene1211	3.77e-321	987.0	COG0436@1|root,COG0436@2|Bacteria,1TQP8@1239|Firmicutes,24BFE@186801|Clostridia,25R7E@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	aspD	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD1_k127_1392218_102	1476973.JMMB01000007_gene1210	1.859e-118	385.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,25RKV@186804|Peptostreptococcaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
HKD1_k127_1392218_53	1476973.JMMB01000007_gene1209	2.535e-188	592.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,25R7V@186804|Peptostreptococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
HKD1_k127_1392218_47	1476973.JMMB01000007_gene1208	3.751e-201	631.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,25QGT@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
HKD1_k127_1392218_157	398512.JQKC01000010_gene139	3.702e-54	203.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3WJ19@541000|Ruminococcaceae	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
HKD1_k127_1392218_43	1476973.JMMB01000007_gene1206	1.323e-206	646.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,25QIY@186804|Peptostreptococcaceae	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
HKD1_k127_1392218_19	1476973.JMMB01000007_gene1205	1.004e-271	842.0	COG0265@1|root,COG0265@2|Bacteria,1UJ6Y@1239|Firmicutes,25EX9@186801|Clostridia,25R4K@186804|Peptostreptococcaceae	186801|Clostridia	O	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
HKD1_k127_1392218_1	1476973.JMMB01000007_gene1204	0.0	1639.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25R3E@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD1_k127_1392218_109	1476973.JMMB01000007_gene1203	7.443e-115	372.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,25RAF@186804|Peptostreptococcaceae	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
HKD1_k127_1392218_103	1476973.JMMB01000007_gene1202	4.063e-118	380.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24DJD@186801|Clostridia,25QP2@186804|Peptostreptococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
HKD1_k127_1392218_107	1476973.JMMB01000007_gene1201	2.533e-116	375.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,25SYF@186804|Peptostreptococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
HKD1_k127_1392218_134	1391646.AVSU01000165_gene846	5.369e-85	284.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,25CJR@186801|Clostridia,25UMM@186804|Peptostreptococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HKD1_k127_1392218_35	1476973.JMMB01000007_gene1198	2.18e-217	678.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,25QIX@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HKD1_k127_1392218_156	1540257.JQMW01000011_gene2561	3.501e-54	198.0	COG1266@1|root,COG1266@2|Bacteria,1V47I@1239|Firmicutes,24H0K@186801|Clostridia,36IHA@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD1_k127_1392218_95	1476973.JMMB01000007_gene1197	9.164e-132	422.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,24BPJ@186801|Clostridia,25UJ0@186804|Peptostreptococcaceae	186801|Clostridia	C	Iron/manganese superoxide dismutases, alpha-hairpin domain	sod	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	LysM,Sod_Fe_C,Sod_Fe_N
HKD1_k127_1392218_132	1476973.JMMB01000007_gene1196	2.32e-88	294.0	COG1988@1|root,COG1988@2|Bacteria,1V3QT@1239|Firmicutes,24WWI@186801|Clostridia,25TBS@186804|Peptostreptococcaceae	186801|Clostridia	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD1_k127_1392218_121	1476973.JMMB01000007_gene1195	2.53e-100	330.0	COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,24RD7@186801|Clostridia,25UF9@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_1392218_89	1476973.JMMB01000007_gene1194	2.066e-143	459.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,25QZ6@186804|Peptostreptococcaceae	186801|Clostridia	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
HKD1_k127_1392218_151	457396.CSBG_02214	2.437e-62	218.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,36IGD@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
HKD1_k127_1392218_92	1476973.JMMB01000007_gene1193	7.773e-136	435.0	COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,249V2@186801|Clostridia,25SSU@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.3.90	ko:K06896	ko00500,map00500	-	R10486	RC00017	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
HKD1_k127_1392218_39	1391646.AVSU01000010_gene74	1.133e-214	670.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,25T3C@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	2.7.1.208	ko:K20107,ko:K20108	ko00500,ko02060,map00500,map02060	M00806	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD1_k127_1392218_133	1476973.JMMB01000007_gene1191	9.215e-86	286.0	COG1263@1|root,COG1263@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,25T3C@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	2.7.1.208	ko:K20107,ko:K20108	ko00500,ko02060,map00500,map02060	M00806	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD1_k127_1392218_13	1476973.JMMB01000007_gene1190	0.0	1007.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,25T4K@186804|Peptostreptococcaceae	186801|Clostridia	G	Alpha-amylase domain	gsj	-	3.2.1.1,3.2.1.20	ko:K01176,ko:K01187	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00028,R00801,R00802,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
HKD1_k127_1392218_118	1476973.JMMB01000007_gene1189	2.204e-106	346.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25S8X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD1_k127_1392218_77	1476973.JMMB01000007_gene1188	1.632e-153	486.0	COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,2499B@186801|Clostridia,25SCA@186804|Peptostreptococcaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD1_k127_1392218_32	1476973.JMMB01000007_gene1187	9.143e-223	693.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25QWM@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
HKD1_k127_1392218_106	1476973.JMMB01000007_gene1186	2.19e-116	379.0	COG2508@1|root,COG2508@2|Bacteria,1UESS@1239|Firmicutes,25JS8@186801|Clostridia,25TC5@186804|Peptostreptococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD1_k127_1392218_125	1476973.JMMB01000007_gene2227	2.637e-98	325.0	arCOG03165@1|root,30AIC@2|Bacteria,1V7NB@1239|Firmicutes,24M5X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_127	1476973.JMMB01000007_gene1185	2.658e-96	317.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,25SKS@186804|Peptostreptococcaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD1_k127_1392218_9	1476973.JMMB01000007_gene1184	0.0	1058.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,25R41@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC-2 type transporter	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
HKD1_k127_1392218_140	1391646.AVSU01000074_gene2785	1.987e-82	274.0	COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,24H9Q@186801|Clostridia,25T4U@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10460	AdoMet_dc
HKD1_k127_1392218_33	1391646.AVSU01000074_gene2784	3.12e-219	689.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25SYA@186804|Peptostreptococcaceae	186801|Clostridia	E	Orn/Lys/Arg decarboxylase, C-terminal domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD1_k127_1392218_160	1476973.JMMB01000007_gene1183	3.692e-53	190.0	293ES@1|root,2ZQX7@2|Bacteria,1W3MC@1239|Firmicutes,2577A@186801|Clostridia,25UEM@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_170	1476973.JMMB01000007_gene1182	6.756e-40	149.0	2DZWG@1|root,32VKS@2|Bacteria,1VE6T@1239|Firmicutes,24Q6X@186801|Clostridia	186801|Clostridia	S	TIGRFAM phage holin, LL-H	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_6_1
HKD1_k127_1392218_139	1301100.HG529351_gene4255	5.386e-84	282.0	2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,24HSZ@186801|Clostridia,36IQJ@31979|Clostridiaceae	186801|Clostridia	S	Tryptophan transporter TrpP	trpP	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS14305	TrpP
HKD1_k127_1392218_48	1476973.JMMB01000007_gene1181	4.219e-200	627.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,25R7D@186804|Peptostreptococcaceae	186801|Clostridia	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
HKD1_k127_1392218_96	1476973.JMMB01000007_gene1180	3.495e-129	414.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,25REY@186804|Peptostreptococcaceae	186801|Clostridia	S	tRNA (adenine(22)-N(1))-methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
HKD1_k127_1392218_45	1391646.AVSU01000053_gene935	1.657e-205	645.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25QZG@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_1392218_7	1476973.JMMB01000007_gene1177	0.0	1088.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25QPP@186804|Peptostreptococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HKD1_k127_1392218_72	1476973.JMMB01000007_gene1176	9.329e-159	501.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,25T7Y@186804|Peptostreptococcaceae	186801|Clostridia	E	DAHP synthetase I family	aroF	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
HKD1_k127_1392218_149	445973.CLOBAR_01934	7.742e-68	234.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,25RXF@186804|Peptostreptococcaceae	186801|Clostridia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
HKD1_k127_1392218_169	293826.Amet_2162	5.108e-43	160.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,36KQB@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
HKD1_k127_1392218_81	1476973.JMMB01000007_gene1173	3.943e-148	471.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,25R4S@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
HKD1_k127_1392218_110	1476973.JMMB01000007_gene1172	2.854e-114	370.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25RGH@186804|Peptostreptococcaceae	186801|Clostridia	F	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD1_k127_1392218_128	1476973.JMMB01000007_gene1171	2.123e-93	311.0	2F23J@1|root,33V28@2|Bacteria,1VV5V@1239|Firmicutes,25Q5H@186801|Clostridia,25RQE@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_173	999411.HMPREF1092_00550	2.695e-36	147.0	COG0115@1|root,COG0115@2|Bacteria,1V3JS@1239|Firmicutes,24JA5@186801|Clostridia,36ISU@31979|Clostridiaceae	186801|Clostridia	EH	Aminotransferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
HKD1_k127_1392218_23	1476973.JMMB01000007_gene1169	1.998e-255	792.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,25QW7@186804|Peptostreptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
HKD1_k127_1392218_111	1476973.JMMB01000007_gene1168	9.159e-113	366.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25QXV@186804|Peptostreptococcaceae	186801|Clostridia	EH	Peptidase C26	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17720	GATase
HKD1_k127_1392218_158	1301100.HG529352_gene4272	8.86e-54	190.0	2ED4Q@1|root,3371F@2|Bacteria,1VHKU@1239|Firmicutes,24WZ4@186801|Clostridia,36VDX@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_97	1476973.JMMB01000007_gene1166	8.154e-127	407.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia,25SCY@186804|Peptostreptococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
HKD1_k127_1392218_84	1476973.JMMB01000007_gene1165	1.021e-145	467.0	COG2340@1|root,COG2340@2|Bacteria,1TSUX@1239|Firmicutes,24HJ4@186801|Clostridia,25RBU@186804|Peptostreptococcaceae	186801|Clostridia	S	CAP-associated N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CAP_assoc_N,Cu_amine_oxidN1
HKD1_k127_1392218_85	1476973.JMMB01000007_gene1164	1.046e-145	464.0	COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes,24GQA@186801|Clostridia,25UK9@186804|Peptostreptococcaceae	186801|Clostridia	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
HKD1_k127_1392218_87	1476973.JMMB01000007_gene1163	5.386e-145	463.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,25QW3@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD1_k127_1392218_105	1476973.JMMB01000007_gene1162	5.111e-117	379.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,25QZU@186804|Peptostreptococcaceae	186801|Clostridia	M	LrgB-like family	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
HKD1_k127_1392218_162	1476973.JMMB01000007_gene1161	7.842e-49	178.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,25JC7@186801|Clostridia,25RXC@186804|Peptostreptococcaceae	186801|Clostridia	S	LrgA family	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
HKD1_k127_1392218_52	1476973.JMMB01000007_gene1160	2.303e-192	602.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,25SPN@186804|Peptostreptococcaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
HKD1_k127_1392218_36	1476973.JMMB01000007_gene1159	3.443e-217	681.0	COG1729@1|root,COG1729@2|Bacteria,1VDE3@1239|Firmicutes,25EWU@186801|Clostridia,25QQS@186804|Peptostreptococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TPR_8
HKD1_k127_1392218_119	1476973.JMMB01000007_gene1158	1.05e-104	342.0	COG2203@1|root,COG2203@2|Bacteria,1UVPA@1239|Firmicutes,25KK8@186801|Clostridia,25R8M@186804|Peptostreptococcaceae	186801|Clostridia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
HKD1_k127_1392218_38	1476973.JMMB01000007_gene1157	9.102e-215	677.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25QWE@186804|Peptostreptococcaceae	186801|Clostridia	V	G5	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HKD1_k127_1392218_29	1476973.JMMB01000007_gene1156	3.671e-224	702.0	2CAI1@1|root,33A6T@2|Bacteria,1VND1@1239|Firmicutes,24XZB@186801|Clostridia,25RF2@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_112	1476973.JMMB01000007_gene1155	1.397e-110	362.0	COG0631@1|root,COG0631@2|Bacteria,1V75W@1239|Firmicutes,24KMZ@186801|Clostridia,25RNA@186804|Peptostreptococcaceae	186801|Clostridia	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HKD1_k127_1392218_182	1476973.JMMB01000007_gene1154	5.857e-24	104.0	28RCB@1|root,2ZDRR@2|Bacteria,1W1HT@1239|Firmicutes,2564F@186801|Clostridia,25U6Q@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_8	1476973.JMMB01000007_gene1153	0.0	1067.0	COG0450@1|root,COG3325@1|root,COG0450@2|Bacteria,COG3325@2|Bacteria,1TQU7@1239|Firmicutes,24A31@186801|Clostridia,25QUM@186804|Peptostreptococcaceae	186801|Clostridia	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA,Glyco_hydro_18
HKD1_k127_1392218_113	1301100.HG529258_gene6214	5.509e-110	358.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia,36GMV@31979|Clostridiaceae	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
HKD1_k127_1392218_21	1476973.JMMB01000007_gene1151	3.803e-260	807.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25SK9@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HKD1_k127_1392218_73	1476973.JMMB01000007_gene1150	1.345e-156	499.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25R6C@186804|Peptostreptococcaceae	186801|Clostridia	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HKD1_k127_1392218_2	1476973.JMMB01000007_gene1149	0.0	1551.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia,25R57@186804|Peptostreptococcaceae	186801|Clostridia	KL	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
HKD1_k127_1392218_68	1301100.HG529257_gene6221	1.982e-161	511.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,36DZP@31979|Clostridiaceae	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD1_k127_1392218_141	1476973.JMMB01000007_gene1147	1.134e-81	274.0	2FI34@1|root,349VW@2|Bacteria,1VYWE@1239|Firmicutes,251CD@186801|Clostridia,25RUA@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_22	1476973.JMMB01000007_gene1146	1.566e-257	799.0	COG1387@1|root,COG1387@2|Bacteria,1VUGT@1239|Firmicutes,25F7D@186801|Clostridia,25REM@186804|Peptostreptococcaceae	186801|Clostridia	E	Histidinol phosphatase and related hydrolases of the PHP family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,DUF3604
HKD1_k127_1392218_189	1301100.HG529256_gene6204	3.723e-05	46.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V0RM@1239|Firmicutes,24C7M@186801|Clostridia,36F4B@31979|Clostridiaceae	186801|Clostridia	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
HKD1_k127_1392218_131	1301100.HG529256_gene6203	1.387e-90	303.0	COG1284@1|root,COG1284@2|Bacteria,1V2BR@1239|Firmicutes,247P9@186801|Clostridia,36HK1@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HKD1_k127_1392218_150	1476973.JMMB01000007_gene1142	1.774e-62	218.0	COG3238@1|root,COG3238@2|Bacteria,1VN6S@1239|Firmicutes,251CM@186801|Clostridia,25TK7@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HKD1_k127_1392218_143	1476973.JMMB01000007_gene1141	6.555e-79	267.0	2F5I7@1|root,33Y3N@2|Bacteria,1VVMQ@1239|Firmicutes,250CH@186801|Clostridia,25RNV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HKD1_k127_1392218_59	1476973.JMMB01000007_gene1140	2.106e-178	572.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25QIR@186804|Peptostreptococcaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HKD1_k127_1392218_51	1476973.JMMB01000007_gene1139	1.927e-194	607.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25QUN@186804|Peptostreptococcaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HKD1_k127_1392218_120	1476973.JMMB01000007_gene1137	1.267e-101	332.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,25RC4@186804|Peptostreptococcaceae	186801|Clostridia	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HKD1_k127_1392218_124	1301100.HG529256_gene6196	7.284e-99	325.0	2ESIJ@1|root,33QBY@2|Bacteria,1VSRZ@1239|Firmicutes,25DWX@186801|Clostridia	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HKD1_k127_1392218_116	1391646.AVSU01000043_gene1452	3.231e-108	355.0	COG0561@1|root,COG0561@2|Bacteria,1V2ZR@1239|Firmicutes,24IRJ@186801|Clostridia,25T98@186804|Peptostreptococcaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD1_k127_1392218_34	1476973.JMMB01000007_gene1136	4.414e-219	684.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,25QFY@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HKD1_k127_1392218_66	272563.CD630_14080	2.993e-162	514.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,25QJZ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD1_k127_1392218_20	1292035.H476_0751	1.441e-262	814.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25SEM@186804|Peptostreptococcaceae	186801|Clostridia	K	COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HKD1_k127_1392218_130	1301100.HG529256_gene6194	1.104e-91	307.0	COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
HKD1_k127_1392218_6	1476973.JMMB01000007_gene1134	0.0	1130.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,25QNM@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HKD1_k127_1392218_79	1476973.JMMB01000007_gene1133	4.843e-151	480.0	2BM9H@1|root,32FTB@2|Bacteria,1UF0T@1239|Firmicutes,25K1A@186801|Clostridia,25U4S@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_114	1476973.JMMB01000007_gene1132	7.391e-110	357.0	2C5BA@1|root,32RFD@2|Bacteria,1V80B@1239|Firmicutes,24HQU@186801|Clostridia,25RGN@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3867
HKD1_k127_1392218_76	1476973.JMMB01000007_gene1131	2.958e-154	491.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,25QKS@186804|Peptostreptococcaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HKD1_k127_1392218_61	1151292.QEW_1778	5.217e-178	567.0	COG0673@1|root,COG0673@2|Bacteria,1TRCC@1239|Firmicutes,248FQ@186801|Clostridia,25S5D@186804|Peptostreptococcaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_1392218_56	1476973.JMMB01000007_gene1129	2.157e-183	582.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_1392218_154	1476973.JMMB01000007_gene1128	2.154e-60	215.0	COG0251@1|root,COG0251@2|Bacteria,1VDW8@1239|Firmicutes,24KN3@186801|Clostridia,25RMT@186804|Peptostreptococcaceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
HKD1_k127_1392218_62	1151292.QEW_1771	3.531e-175	553.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,25UAX@186804|Peptostreptococcaceae	186801|Clostridia	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HKD1_k127_1392218_108	1151292.QEW_1770	1.812e-115	376.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia	186801|Clostridia	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
HKD1_k127_1392218_44	1151292.QEW_1769	8.067e-206	646.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,2490P@186801|Clostridia	186801|Clostridia	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
HKD1_k127_1392218_100	1151292.QEW_1768	6.621e-121	394.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HKD1_k127_1392218_142	1476973.JMMB01000007_gene1127	1.879e-79	267.0	2F1PT@1|root,33UQ3@2|Bacteria,1VUVA@1239|Firmicutes,250KK@186801|Clostridia,25REE@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_164	1476973.JMMB01000007_gene1126	5.104e-47	169.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,25RS1@186804|Peptostreptococcaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
HKD1_k127_1392218_181	1408823.AXUS01000004_gene219	9.251e-25	109.0	29USB@1|root,30G4F@2|Bacteria,1UF5Y@1239|Firmicutes,25K6U@186801|Clostridia,25U8X@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_91	1476973.JMMB01000007_gene1125	9.43e-138	441.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25SC0@186804|Peptostreptococcaceae	186801|Clostridia	O	peptidyl-prolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HKD1_k127_1392218_144	1476973.JMMB01000007_gene1124	3.54e-78	262.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,25RRK@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_1392218_175	1151292.QEW_1737	8.387e-35	133.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25RUN@186804|Peptostreptococcaceae	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_1392218_28	1476973.JMMB01000007_gene1122	2.472e-227	707.0	COG3170@1|root,COG3170@2|Bacteria,1TR7V@1239|Firmicutes,247XU@186801|Clostridia,25R2T@186804|Peptostreptococcaceae	186801|Clostridia	NU	Putative amidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
HKD1_k127_1392218_82	1476973.JMMB01000007_gene1121	9.882e-148	471.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,25QMD@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the pyridoxine kinase family	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
HKD1_k127_1392218_166	1476973.JMMB01000007_gene1120	2.48e-46	169.0	2F3EM@1|root,33W8E@2|Bacteria,1VMKT@1239|Firmicutes,24JAI@186801|Clostridia,25RV2@186804|Peptostreptococcaceae	186801|Clostridia	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD1_k127_1392218_71	1476973.JMMB01000007_gene1119	7.07e-159	510.0	2F5AB@1|root,33XWG@2|Bacteria,1VVKK@1239|Firmicutes,24Y48@186801|Clostridia,25RHQ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_179	1476973.JMMB01000007_gene1118	1.434e-30	123.0	2BDYB@1|root,327NM@2|Bacteria,1UTJ0@1239|Firmicutes,25387@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_146	1476973.JMMB01000007_gene1117	3.252e-74	254.0	2DXB9@1|root,34484@2|Bacteria,1W00R@1239|Firmicutes,25JX5@186801|Clostridia,25TRQ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_49	1476973.JMMB01000007_gene1113	3.219e-197	617.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia,25S9H@186804|Peptostreptococcaceae	186801|Clostridia	E	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HKD1_k127_1392218_40	1476973.JMMB01000007_gene1112	1.486e-210	662.0	COG3314@1|root,COG3314@2|Bacteria,1VUTU@1239|Firmicutes,25MQP@186801|Clostridia,25RG6@186804|Peptostreptococcaceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_46	1476973.JMMB01000007_gene1111	2.557e-205	642.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,25RD8@186804|Peptostreptococcaceae	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
HKD1_k127_1392218_153	1476973.JMMB01000007_gene1110	1.471e-61	220.0	29UP4@1|root,30G0Q@2|Bacteria,1UEZG@1239|Firmicutes,25JZM@186801|Clostridia,25U0B@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_115	1476973.JMMB01000007_gene1109	2.235e-108	357.0	COG4942@1|root,COG4942@2|Bacteria,1VFP3@1239|Firmicutes,25KZC@186801|Clostridia,25TGS@186804|Peptostreptococcaceae	186801|Clostridia	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD1_k127_1392218_5	1476973.JMMB01000007_gene1107	0.0	1148.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,25QY5@186804|Peptostreptococcaceae	186801|Clostridia	E	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
HKD1_k127_1392218_80	1476973.JMMB01000007_gene1106	2.094e-150	477.0	COG5018@1|root,COG5018@2|Bacteria,1VAUM@1239|Firmicutes,25DMJ@186801|Clostridia,25UNC@186804|Peptostreptococcaceae	186801|Clostridia	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HKD1_k127_1392218_159	1476973.JMMB01000007_gene1105	2.567e-53	189.0	2BM8C@1|root,32FS2@2|Bacteria,1UF0G@1239|Firmicutes,252JJ@186801|Clostridia,25U3K@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_78	1301100.HG529252_gene6254	1.586e-151	480.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,36E73@31979|Clostridiaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HKD1_k127_1392218_69	1476973.JMMB01000007_gene1103	2.001e-161	512.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,25SF7@186804|Peptostreptococcaceae	186801|Clostridia	H	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
HKD1_k127_1392218_25	1476973.JMMB01000007_gene1102	1.626e-253	783.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25QPU@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_1392218_145	1476973.JMMB01000007_gene1101	1.572e-75	256.0	COG1846@1|root,COG1846@2|Bacteria,1VH12@1239|Firmicutes,25ATV@186801|Clostridia,25RIR@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_1392218_17	1476973.JMMB01000007_gene1100	3.587e-295	908.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25QVH@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HKD1_k127_1392218_63	1476973.JMMB01000007_gene1099	1.106e-174	550.0	COG4974@1|root,COG4974@2|Bacteria,1VEXF@1239|Firmicutes,25JG3@186801|Clostridia,25SDQ@186804|Peptostreptococcaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
HKD1_k127_1392218_86	1476973.JMMB01000007_gene1098	4.464e-145	463.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25QTP@186804|Peptostreptococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HKD1_k127_1392218_15	1476973.JMMB01000007_gene1097	6.475e-319	983.0	COG0210@1|root,COG0210@2|Bacteria,1TP8F@1239|Firmicutes,24GBP@186801|Clostridia,25R7M@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD-helicase,UvrD_C,UvrD_C_2
HKD1_k127_1392218_171	1476973.JMMB01000007_gene1096	7.715e-39	146.0	2BM7Q@1|root,32FRF@2|Bacteria,1UF03@1239|Firmicutes,253A0@186801|Clostridia,25U2F@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_16	1476973.JMMB01000007_gene1093	1.684e-303	934.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25R0R@186804|Peptostreptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HKD1_k127_1392218_42	1476973.JMMB01000007_gene1092	4.349e-208	648.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,25QH2@186804|Peptostreptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HKD1_k127_1392218_147	1408823.AXUS01000004_gene240	5.223e-70	241.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25RAN@186804|Peptostreptococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HKD1_k127_1392218_18	1476973.JMMB01000007_gene1090	8.999e-275	847.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25QPV@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HKD1_k127_1392218_58	1476973.JMMB01000007_gene1089	7.013e-181	570.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,24AM7@186801|Clostridia,25T6W@186804|Peptostreptococcaceae	186801|Clostridia	S	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
HKD1_k127_1392218_4	1476973.JMMB01000007_gene1088	0.0	1299.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25QQ1@186804|Peptostreptococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD1_k127_1392218_93	1476973.JMMB01000007_gene1087	8.138e-135	433.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,25QMI@186804|Peptostreptococcaceae	186801|Clostridia	OU	Clp protease	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD1_k127_1392218_37	1476973.JMMB01000007_gene1086	3.129e-216	676.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25QHR@186804|Peptostreptococcaceae	186801|Clostridia	E	ACT domain	dapG	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
HKD1_k127_1392218_167	1476973.JMMB01000007_gene1085	8.189e-46	166.0	COG1873@1|root,COG1873@2|Bacteria,1VEJW@1239|Firmicutes,25JAQ@186801|Clostridia,25RRI@186804|Peptostreptococcaceae	186801|Clostridia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD1_k127_1392218_30	1476973.JMMB01000007_gene1084	3.849e-224	699.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25R7J@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_1392218_90	1476973.JMMB01000007_gene1083	1.021e-138	443.0	COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,25B0J@186801|Clostridia,25SEP@186804|Peptostreptococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_1392218_3	1476973.JMMB01000007_gene1082	0.0	1330.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25QG3@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HKD1_k127_1392218_163	1476973.JMMB01000007_gene1079	1.955e-48	173.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,25RQW@186804|Peptostreptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HKD1_k127_1392218_75	1476973.JMMB01000007_gene1078	1.981e-154	492.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,25QRH@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HKD1_k127_1392218_54	1476973.JMMB01000007_gene1077	4.751e-184	576.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,25QIQ@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
HKD1_k127_1392218_64	1476973.JMMB01000007_gene1076	7.162e-173	546.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25R43@186804|Peptostreptococcaceae	186801|Clostridia	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HKD1_k127_1392218_161	445973.CLOBAR_02162	2.529e-51	184.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25RK5@186804|Peptostreptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HKD1_k127_1392218_12	272563.CD630_13090	0.0	1030.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,25QYU@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HKD1_k127_1392218_155	1476973.JMMB01000007_gene1073	3.117e-56	198.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,25RPK@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HKD1_k127_1392218_174	1408823.AXUS01000004_gene264	3.598e-35	136.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,25RRU@186804|Peptostreptococcaceae	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HKD1_k127_1392218_50	1301100.HG529251_gene6272	1.182e-194	610.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,36DXE@31979|Clostridiaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HKD1_k127_1392218_135	1476973.JMMB01000007_gene1069	1.45e-84	281.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,25RPF@186804|Peptostreptococcaceae	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HKD1_k127_1392218_123	1292035.H476_1526	1.436e-99	327.0	COG0348@1|root,COG0348@2|Bacteria,1UHUA@1239|Firmicutes,24BED@186801|Clostridia,25R8F@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
HKD1_k127_1392218_180	1301100.HG529388_gene5015	2.013e-27	112.0	COG1245@1|root,COG1245@2|Bacteria,1VMA7@1239|Firmicutes,24UN4@186801|Clostridia,36N2D@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HKD1_k127_1392218_55	1292035.H476_2356	1.37e-183	584.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_1392218_94	1292035.H476_2357	2.685e-132	428.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V0RM@1239|Firmicutes,24C7M@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
HKD1_k127_1392218_98	1301100.HG529358_gene2037	2.339e-122	394.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36EH8@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_1392218_11	1301100.HG529358_gene2038	0.0	1043.0	COG0577@1|root,COG0577@2|Bacteria,1TV1M@1239|Firmicutes,24E2X@186801|Clostridia,36H13@31979|Clostridiaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
HKD1_k127_1392218_99	1151292.QEW_0513	4.82e-122	398.0	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,247YE@186801|Clostridia,25RXP@186804|Peptostreptococcaceae	186801|Clostridia	T	GHKL domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_5,SPOB_a
HKD1_k127_1392218_88	1301100.HG529358_gene2040	1.415e-144	460.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_1392218_178	318464.IO99_07155	5.068e-32	133.0	COG0789@1|root,COG0789@2|Bacteria,1VYT6@1239|Firmicutes,24F3I@186801|Clostridia,36HSW@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD1_k127_1392218_0	1476973.JMMB01000007_gene1067	0.0	2636.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,25QR9@186804|Peptostreptococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HKD1_k127_1392218_101	1476973.JMMB01000007_gene1066	3.767e-120	388.0	2F4QN@1|root,33XDP@2|Bacteria,1VVWB@1239|Firmicutes,24Z5D@186801|Clostridia,25RIX@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_31	1476973.JMMB01000007_gene1065	5.637e-224	705.0	COG3103@1|root,COG4193@1|root,COG3103@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,25UK8@186804|Peptostreptococcaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
HKD1_k127_1392218_136	1476973.JMMB01000007_gene1064	3.292e-84	280.0	2BDCP@1|root,3271F@2|Bacteria,1USXD@1239|Firmicutes,25060@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1392218_26	1476973.JMMB01000007_gene395	1.363e-236	734.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25QJU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HKD1_k127_1392218_70	1391646.AVSU01000074_gene2787	1.486e-160	508.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia	186801|Clostridia	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD1_k127_1392218_57	1391646.AVSU01000074_gene2786	8.686e-183	572.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,25S3F@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
HKD1_k127_1392218_138	1301100.HG529358_gene2022	5.084e-84	278.0	COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,24H9Q@186801|Clostridia,36ITN@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10460	AdoMet_dc
HKD1_k127_1392218_27	1391646.AVSU01000074_gene2784	6.733e-236	737.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25SYA@186804|Peptostreptococcaceae	186801|Clostridia	E	Orn/Lys/Arg decarboxylase, C-terminal domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD1_k127_1392218_24	1476973.JMMB01000007_gene1060	1.84e-254	787.0	COG1206@1|root,COG1206@2|Bacteria,1TRKH@1239|Firmicutes,249ZZ@186801|Clostridia,25QNX@186804|Peptostreptococcaceae	186801|Clostridia	J	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GIDA
HKD1_k127_1392218_60	1476973.JMMB01000007_gene1059	2.748e-178	561.0	COG0543@1|root,COG0543@2|Bacteria,1U0H3@1239|Firmicutes,249DH@186801|Clostridia,25R1K@186804|Peptostreptococcaceae	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2_3
HKD1_k127_1392218_122	1476973.JMMB01000007_gene1058	6.875e-100	329.0	COG5522@1|root,COG5522@2|Bacteria,1VX4J@1239|Firmicutes,250VD@186801|Clostridia,25T1H@186804|Peptostreptococcaceae	186801|Clostridia	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
HKD1_k127_1392218_152	1476973.JMMB01000007_gene1057	3.043e-62	217.0	COG1846@1|root,COG1846@2|Bacteria,1VXUG@1239|Firmicutes,24TEW@186801|Clostridia,25TKG@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
HKD1_k127_1392218_185	398512.JQKC01000003_gene5078	7.723e-17	85.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HKD1_k127_1392218_148	1476973.JMMB01000007_gene1055	5.804e-69	241.0	2F33I@1|root,33VYH@2|Bacteria,1VWEZ@1239|Firmicutes,250YF@186801|Clostridia,25TST@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
HKD1_k127_1392218_129	1476973.JMMB01000007_gene1054	9.591e-93	306.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,25RCC@186804|Peptostreptococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HKD1_k127_1392218_104	1476973.JMMB01000007_gene1053	5.958e-118	383.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,25RMB@186804|Peptostreptococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HKD1_k127_1392218_117	1476973.JMMB01000007_gene1052	4.897e-108	351.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,25RKB@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase, M50 family	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HKD1_k127_1392218_41	1476973.JMMB01000007_gene1051	1.23e-208	652.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,25QZE@186804|Peptostreptococcaceae	186801|Clostridia	M	Penicillin-binding protein 5, C-terminal domain	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD1_k127_1392218_183	1476973.JMMB01000007_gene1050	5.509e-23	100.0	2CK4U@1|root,2ZN1F@2|Bacteria,1W269@1239|Firmicutes,256DB@186801|Clostridia,25UCB@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	3.1.26.5	ko:K03537	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	-
HKD1_k127_1392218_172	1301100.HG529236_gene7254	1.726e-38	145.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,36KRZ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
HKD1_k127_1392218_168	1476973.JMMB01000007_gene1049	6.597e-44	162.0	COG3679@1|root,COG3679@2|Bacteria,1TUUK@1239|Firmicutes,25K0I@186801|Clostridia,25U31@186804|Peptostreptococcaceae	186801|Clostridia	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HKD1_k127_1392218_10	1476973.JMMB01000007_gene1048	0.0	1045.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25QRX@186804|Peptostreptococcaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HKD1_k127_1392218_126	272563.CD630_12880	1.143e-97	325.0	COG1988@1|root,COG1988@2|Bacteria,1VKVY@1239|Firmicutes,25JER@186801|Clostridia,25TMR@186804|Peptostreptococcaceae	186801|Clostridia	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
HKD1_k127_1392218_137	1301100.HG529236_gene7250	3.855e-84	280.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,36I3W@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HKD1_k127_1392218_83	1476973.JMMB01000007_gene1045	5.969e-146	467.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25SZ9@186804|Peptostreptococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD1_k127_1392218_165	1476973.JMMB01000007_gene1044	5.774e-47	169.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24V04@186801|Clostridia,25RYS@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HKD1_k127_1392218_177	1301100.HG529236_gene7247	8.099e-34	130.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,36IV4@31979|Clostridiaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD1_k127_1410008_0	1476973.JMMB01000007_gene195	3.603e-306	943.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,25QF4@186804|Peptostreptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HKD1_k127_1410008_3	1476973.JMMB01000007_gene194	2.425e-60	210.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,25RIG@186804|Peptostreptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HKD1_k127_1410008_2	1476973.JMMB01000007_gene193	3.128e-120	388.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,25QKA@186804|Peptostreptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
HKD1_k127_1410008_5	1476973.JMMB01000007_gene192	5.473e-22	96.0	2BQTQ@1|root,32JQF@2|Bacteria,1UF3X@1239|Firmicutes,25K4Q@186801|Clostridia,25UCW@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1410008_1	1476973.JMMB01000007_gene191	3.194e-224	698.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,25QU0@186804|Peptostreptococcaceae	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
HKD1_k127_1410008_4	1476973.JMMB01000007_gene190	1.169e-31	125.0	COG0695@1|root,COG0695@2|Bacteria,1VGAC@1239|Firmicutes,25JB5@186801|Clostridia,25RTW@186804|Peptostreptococcaceae	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
HKD1_k127_1489903_2	1476973.JMMB01000007_gene1844	0.0	1287.0	COG0210@1|root,COG0210@2|Bacteria,1UVP7@1239|Firmicutes,258E8@186801|Clostridia,25TFX@186804|Peptostreptococcaceae	186801|Clostridia	L	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_17	1476973.JMMB01000007_gene1845	3.582e-155	494.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,25R5N@186804|Peptostreptococcaceae	186801|Clostridia	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HKD1_k127_1489903_35	1476973.JMMB01000007_gene2176	3.834e-83	278.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,25RKY@186804|Peptostreptococcaceae	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
HKD1_k127_1489903_11	1301100.HG529239_gene7212	3.047e-188	593.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,248MC@186801|Clostridia,36H4B@31979|Clostridiaceae	186801|Clostridia	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
HKD1_k127_1489903_40	1476973.JMMB01000007_gene1734	2.039e-51	186.0	2BSDB@1|root,32MFA@2|Bacteria,1UTIU@1239|Firmicutes,2537G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_27	1292035.H476_2465	3.537e-106	356.0	COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,25JU5@186801|Clostridia,25TH3@186804|Peptostreptococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
HKD1_k127_1489903_29	1301100.HG529409_gene170	1.45e-104	342.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	-	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD1_k127_1489903_28	1301100.HG529409_gene171	4.344e-106	347.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,25E61@186801|Clostridia,36UK0@31979|Clostridiaceae	186801|Clostridia	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
HKD1_k127_1489903_10	1301100.HG529409_gene172	7.68e-191	602.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HKD1_k127_1489903_25	1476973.JMMB01000004_gene3423	1.133e-115	375.0	COG0778@1|root,COG0778@2|Bacteria,1V4UA@1239|Firmicutes,24EVR@186801|Clostridia	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
HKD1_k127_1489903_23	1476973.JMMB01000007_gene1576	3.694e-126	407.0	2BJYI@1|root,32EB9@2|Bacteria,1UEC3@1239|Firmicutes,24YBM@186801|Clostridia,25S72@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_45	1476973.JMMB01000007_gene1574	2.137e-28	118.0	2BH9U@1|root,32BBA@2|Bacteria,1TV2R@1239|Firmicutes,25K3H@186801|Clostridia,25U9S@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_8	1476973.JMMB01000007_gene1549	1.292e-227	712.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25S29@186804|Peptostreptococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS
HKD1_k127_1489903_22	1476973.JMMB01000007_gene1548	1.794e-129	415.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_1489903_42	1476973.JMMB01000007_gene1547	1.079e-40	152.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,25RVJ@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
HKD1_k127_1489903_18	1476973.JMMB01000007_gene1546	5.114e-135	432.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,25SD1@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
HKD1_k127_1489903_14	1476973.JMMB01000007_gene1569	4.008e-164	520.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia	186801|Clostridia	I	Alpha beta	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
HKD1_k127_1489903_1	1476973.JMMB01000007_gene1568	0.0	1604.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25R66@186804|Peptostreptococcaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HKD1_k127_1489903_7	1476973.JMMB01000007_gene1567	3.828e-229	713.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25R9Z@186804|Peptostreptococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HKD1_k127_1489903_47	1292035.H476_0641	2.629e-19	88.0	29UPW@1|root,30G1K@2|Bacteria,1UF1G@1239|Firmicutes,254T4@186801|Clostridia,25U72@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_34	1391646.AVSU01000040_gene1906	1.443e-88	302.0	COG4640@1|root,COG4640@2|Bacteria,1VN48@1239|Firmicutes,24NFC@186801|Clostridia,25RKU@186804|Peptostreptococcaceae	186801|Clostridia	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
HKD1_k127_1489903_48	1301100.HG529268_gene630	2.089e-17	82.0	2AFHW@1|root,315IG@2|Bacteria,1UUJF@1239|Firmicutes,256Y4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_24	1476973.JMMB01000007_gene1979	3.34e-124	402.0	COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,25CJA@186801|Clostridia	186801|Clostridia	S	ABC transporter (Permease)	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HKD1_k127_1489903_43	1476973.JMMB01000007_gene1980	1.17e-35	137.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,25TK6@186804|Peptostreptococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_1489903_26	1476973.JMMB01000007_gene1980	4.116e-109	355.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,25TK6@186804|Peptostreptococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_1489903_49	457396.CSBG_02619	1.275e-11	70.0	29V7K@1|root,30GME@2|Bacteria,1UGAC@1239|Firmicutes,24NRE@186801|Clostridia,36KQW@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
HKD1_k127_1489903_39	1499684.CCNP01000021_gene2752	1.156e-56	201.0	COG3279@1|root,COG3279@2|Bacteria,1VG3R@1239|Firmicutes,24JN9@186801|Clostridia,36J9Y@31979|Clostridiaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HKD1_k127_1489903_16	1301100.HG529329_gene4447	7.497e-157	500.0	COG1082@1|root,COG1082@2|Bacteria,1U2VB@1239|Firmicutes,24EE7@186801|Clostridia,36GG0@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_1489903_21	1301100.HG529267_gene582	1.526e-129	417.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,36F35@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
HKD1_k127_1489903_19	1476973.JMMB01000007_gene1062	6.487e-134	431.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,25R9E@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_1489903_15	1476973.JMMB01000007_gene1063	1.499e-157	499.0	COG0778@1|root,COG1145@1|root,COG0778@2|Bacteria,COG1145@2|Bacteria,1TPKH@1239|Firmicutes,249WN@186801|Clostridia,25R44@186804|Peptostreptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_9,Nitroreductase
HKD1_k127_1489903_36	1128398.Curi_c28900	5.676e-83	291.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia,26BDI@186813|unclassified Clostridiales	186801|Clostridia	T	diguanylate cyclase	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GGDEF,Response_reg
HKD1_k127_1489903_32	1174504.AJTN02000241_gene4330	9.306e-96	339.0	COG0745@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli,1ZCFX@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HAMP,HATPase_c,HisKA,Response_reg
HKD1_k127_1489903_44	1385514.N782_04030	3.611e-31	126.0	COG0745@1|root,COG0745@2|Bacteria,1VAYR@1239|Firmicutes,4HKT2@91061|Bacilli,2YAI8@289201|Pontibacillus	91061|Bacilli	KT	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HKD1_k127_1489903_46	1345695.CLSA_c04760	9.911e-22	102.0	2C13D@1|root,33CRB@2|Bacteria,1VNXI@1239|Firmicutes,24N9P@186801|Clostridia,36MCB@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1489903_30	272563.CD630_18010	8.487e-101	337.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,25RQX@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD1_k127_1489903_33	1292035.H476_1513	8.697e-91	304.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,25T5M@186804|Peptostreptococcaceae	186801|Clostridia	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
HKD1_k127_1489903_38	1499683.CCFF01000014_gene3622	3.631e-66	235.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,25CEG@186801|Clostridia,36WUK@31979|Clostridiaceae	186801|Clostridia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HKD1_k127_1489903_3	1476973.JMMB01000007_gene2905	2.798e-284	880.0	COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,247IW@186801|Clostridia,25S27@186804|Peptostreptococcaceae	186801|Clostridia	L	MutS domain III	mutS2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
HKD1_k127_1489903_9	1476973.JMMB01000007_gene2086	4.32e-217	678.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,25QZY@186804|Peptostreptococcaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
HKD1_k127_1489903_0	1321778.HMPREF1982_01463	0.0	1647.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,269CN@186813|unclassified Clostridiales	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_1489903_20	1321778.HMPREF1982_01464	2.166e-130	418.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,268NY@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_1489903_31	1321778.HMPREF1982_01465	2.039e-100	331.0	COG1309@1|root,COG1309@2|Bacteria,1TSFG@1239|Firmicutes,24AME@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_1489903_12	1151292.QEW_2400	1.219e-176	559.0	COG0846@1|root,COG0846@2|Bacteria,1TXGJ@1239|Firmicutes,25DY2@186801|Clostridia,25T5I@186804|Peptostreptococcaceae	186801|Clostridia	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
HKD1_k127_1489903_5	1476973.JMMB01000007_gene1949	2.335e-257	797.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,25S3A@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
HKD1_k127_1489903_4	1476973.JMMB01000007_gene1950	1.309e-279	862.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia,25RW0@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
HKD1_k127_1489903_6	1476973.JMMB01000007_gene1963	1.533e-245	764.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25QX9@186804|Peptostreptococcaceae	186801|Clostridia	V	MATE efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_1489903_13	1476973.JMMB01000007_gene1964	3.85e-173	545.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,25SDF@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_150153_13	1476973.JMMB01000007_gene332	2.232e-62	218.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia,25TJS@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-70, region 4	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_150153_9	1292035.H476_1480	6.086e-102	344.0	COG5513@1|root,COG5513@2|Bacteria,1UIU3@1239|Firmicutes,25ERV@186801|Clostridia,25ST1@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4163)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
HKD1_k127_150153_21	332101.JIBU02000023_gene4831	2.179e-06	59.0	2DR9X@1|root,33AUW@2|Bacteria,1VKEA@1239|Firmicutes,24Z0Z@186801|Clostridia,36VEU@31979|Clostridiaceae	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
HKD1_k127_150153_14	1476973.JMMB01000007_gene1333	1.692e-54	192.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25RU3@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_150153_18	1476973.JMMB01000007_gene1334	4.882e-30	119.0	29UE7@1|root,30FQX@2|Bacteria,1UEFY@1239|Firmicutes,255FG@186801|Clostridia,25RZR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_150153_5	1415775.U729_2983	4.194e-151	490.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,36DFZ@31979|Clostridiaceae	186801|Clostridia	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
HKD1_k127_150153_8	1415775.U729_2982	6.454e-105	348.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,36EV6@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD1_k127_150153_16	1301100.HG529383_gene4102	1.484e-51	185.0	COG1959@1|root,COG1959@2|Bacteria,1V4G2@1239|Firmicutes,24MH9@186801|Clostridia,36JU0@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
HKD1_k127_150153_0	1121324.CLIT_2c00680	1.227e-319	986.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
HKD1_k127_150153_19	246194.CHY_0791	1.359e-22	98.0	COG1977@1|root,COG1977@2|Bacteria,1VIUV@1239|Firmicutes,24RKW@186801|Clostridia,42HDN@68295|Thermoanaerobacterales	186801|Clostridia	H	Mut7-C ubiquitin	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD1_k127_150153_10	445335.CBN_2001	8.028e-91	304.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,36GDP@31979|Clostridiaceae	186801|Clostridia	H	UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
HKD1_k127_150153_7	1476973.JMMB01000007_gene1637	1.279e-125	410.0	2DZXK@1|root,32VMK@2|Bacteria,1VBXX@1239|Firmicutes,24MJB@186801|Clostridia,25SHA@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_150153_12	1476973.JMMB01000007_gene1638	4.495e-67	240.0	28YQM@1|root,32ATU@2|Bacteria,1W6QB@1239|Firmicutes,25P85@186801|Clostridia,25TYW@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_150153_6	1476973.JMMB01000007_gene1639	1.012e-148	487.0	2BN2E@1|root,32GNY@2|Bacteria,1UFI1@1239|Firmicutes,25KZB@186801|Clostridia,25STS@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_150153_11	1476973.JMMB01000004_gene3424	3.379e-70	239.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,25TBT@186804|Peptostreptococcaceae	186801|Clostridia	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_150153_4	1476973.JMMB01000007_gene1335	4.382e-158	505.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	M00309,M00541	R08571,R10961	RC00242,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
HKD1_k127_150153_15	1476973.JMMB01000007_gene1336	1.157e-52	191.0	29UE5@1|root,30FQU@2|Bacteria,1UEFT@1239|Firmicutes,25JCM@186801|Clostridia,25RYQ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_150153_1	272563.CD630_21560	8.377e-249	773.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25R1A@186804|Peptostreptococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydG	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HKD1_k127_150153_3	1151292.QEW_2669	3.692e-174	552.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,25QJB@186804|Peptostreptococcaceae	186801|Clostridia	H	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
HKD1_k127_150153_2	272563.CD630_21540	3.999e-203	638.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,25QWW@186804|Peptostreptococcaceae	186801|Clostridia	S	maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
HKD1_k127_150153_17	272563.CD630_21530	3.668e-36	138.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,25TWD@186804|Peptostreptococcaceae	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C
HKD1_k127_1542743_2	1476973.JMMB01000007_gene2313	1.579e-132	426.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,25QSX@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HKD1_k127_1542743_7	1033737.CAEV01000056_gene3768	7.04e-29	122.0	2E66T@1|root,330VC@2|Bacteria,1VHCY@1239|Firmicutes,24MYI@186801|Clostridia,36NA0@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1542743_1	1476973.JMMB01000007_gene1836	1.465e-151	482.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,25T7F@186804|Peptostreptococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
HKD1_k127_1542743_0	1292035.H476_1630	1.974e-253	789.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,25S6S@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid permease	yjeM	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD1_k127_1542743_8	1476973.JMMB01000007_gene1896	4.343e-25	104.0	2C3DI@1|root,33B22@2|Bacteria,1VMAK@1239|Firmicutes,24UHS@186801|Clostridia	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD1_k127_1542743_6	1243664.CAVL020000014_gene1842	1.647e-31	130.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	ycnB	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_1542743_5	545697.HMPREF0216_01374	7.621e-40	152.0	29UZR@1|root,30GCR@2|Bacteria,1UFRM@1239|Firmicutes,24IWR@186801|Clostridia,36IV9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1542743_3	1476973.JMMB01000007_gene2763	6.755e-76	258.0	2DSJR@1|root,33GEZ@2|Bacteria,1VPS4@1239|Firmicutes,25JY0@186801|Clostridia,25TUR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1542743_4	1304284.L21TH_0346	2.726e-47	174.0	COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,24MYP@186801|Clostridia,36IUV@31979|Clostridiaceae	186801|Clostridia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_1565643_4	1301100.HG529247_gene2378	2.78e-179	565.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,36EB5@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HKD1_k127_1565643_5	1301100.HG529247_gene2379	3.283e-157	499.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,36EMV@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HKD1_k127_1565643_12	1280689.AUJC01000004_gene339	2.063e-84	287.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,36DQV@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HKD1_k127_1565643_3	290402.Cbei_1524	4.354e-216	680.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,36DYZ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	GltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
HKD1_k127_1565643_7	1391647.AVSV01000011_gene1116	2.258e-120	391.0	COG0778@1|root,COG1145@1|root,COG0778@2|Bacteria,COG1145@2|Bacteria,1TPKH@1239|Firmicutes,249WN@186801|Clostridia,36FJJ@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_9,Nitroreductase
HKD1_k127_1565643_1	536227.CcarbDRAFT_2909	5.174e-292	898.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,36DZU@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	abgA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HKD1_k127_1565643_20	1391646.AVSU01000013_gene1766	6.179e-05	45.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25RJQ@186804|Peptostreptococcaceae	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_1565643_6	1196029.ALIM01000035_gene2153	1.953e-142	463.0	COG2733@1|root,COG2733@2|Bacteria,1V1AB@1239|Firmicutes,4IRPD@91061|Bacilli,1ZRWC@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD1_k127_1565643_19	1410632.JHWW01000007_gene513	1.834e-06	61.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,27NIR@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,ChW,Peptidase_S8,SLH
HKD1_k127_1565643_11	1347086.CCBA010000010_gene1800	4.832e-107	376.0	COG3227@1|root,COG4733@1|root,COG5184@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,1ZESI@1386|Bacillus	91061|Bacilli	DZ	COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
HKD1_k127_1565643_18	1282887.AUJG01000009_gene1471	1.055e-06	62.0	COG2730@1|root,COG3866@1|root,COG4677@1|root,COG2730@2|Bacteria,COG3866@2|Bacteria,COG4677@2|Bacteria,1TSCD@1239|Firmicutes,24AHP@186801|Clostridia	186801|Clostridia	G	Pectinesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Pectinesterase
HKD1_k127_1565643_17	1391646.AVSU01000091_gene476	1.146e-14	74.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,2492B@186801|Clostridia,25UJM@186804|Peptostreptococcaceae	186801|Clostridia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_1565643_14	1476973.JMMB01000007_gene3010	1.983e-74	250.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,25B3D@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HKD1_k127_1565643_0	1476973.JMMB01000007_gene3009	0.0	1059.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25QT2@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs1	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HKD1_k127_1565643_21	1301100.HG529227_gene5464	7.302e-05	46.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,24UD8@186801|Clostridia,36PEW@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_1565643_8	1304284.L21TH_1415	1.486e-110	373.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
HKD1_k127_1565643_10	1476973.JMMB01000007_gene724	6.95e-108	353.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25SG4@186804|Peptostreptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
HKD1_k127_1565643_9	1301100.HG529275_gene1645	2.161e-109	357.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,36JT4@31979|Clostridiaceae	186801|Clostridia	M	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HKD1_k127_1565643_22	1476973.JMMB01000007_gene724	0.000215	44.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25SG4@186804|Peptostreptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
HKD1_k127_1565643_2	1292035.H476_0612	2.089e-269	842.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,25QVY@186804|Peptostreptococcaceae	186801|Clostridia	GM	CoA-binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HKD1_k127_1565643_13	1511.CLOST_0358	1.455e-83	285.0	COG2301@1|root,COG2301@2|Bacteria,1UNWU@1239|Firmicutes,24CR9@186801|Clostridia	186801|Clostridia	C	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
HKD1_k127_1565643_15	1278306.KB906907_gene12	2.895e-55	199.0	COG2148@1|root,COG2148@2|Bacteria,378EQ@32066|Fusobacteria	32066|Fusobacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
HKD1_k127_1565643_16	203119.Cthe_2647	3.873e-45	171.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HKD1_k127_157103_0	1301100.HG529391_gene5041	0.0	1179.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_157103_8	1476973.JMMB01000007_gene1308	1.26e-74	254.0	29UQF@1|root,30G28@2|Bacteria,1UF2C@1239|Firmicutes,251YJ@186801|Clostridia,25U97@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_157103_6	1476973.JMMB01000007_gene1307	6.274e-106	348.0	2F3DY@1|root,33W7R@2|Bacteria,1VWEQ@1239|Firmicutes,24FKD@186801|Clostridia,25TDK@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_157103_5	1476973.JMMB01000007_gene1306	3.855e-109	356.0	COG1842@1|root,COG1842@2|Bacteria,1TZI1@1239|Firmicutes,259SV@186801|Clostridia,25RYA@186804|Peptostreptococcaceae	186801|Clostridia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
HKD1_k127_157103_7	1301100.HG529282_gene6973	7.524e-81	272.0	COG1514@1|root,COG1514@2|Bacteria,1VUNK@1239|Firmicutes,24G80@186801|Clostridia,36I9F@31979|Clostridiaceae	186801|Clostridia	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
HKD1_k127_157103_4	1151292.QEW_3871	7.649e-170	538.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,25QRZ@186804|Peptostreptococcaceae	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD1_k127_157103_13	1301100.HG529321_gene6074	4.784e-20	92.0	2964T@1|root,2ZTF0@2|Bacteria,1W5EH@1239|Firmicutes,256MD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_157103_10	431943.CKL_0936	5.726e-63	221.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,36DWS@31979|Clostridiaceae	186801|Clostridia	S	hmm pf02632	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HKD1_k127_157103_3	1410653.JHVC01000001_gene1461	6.635e-183	595.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,36UJK@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9
HKD1_k127_157103_12	1476973.JMMB01000007_gene1294	3.619e-30	119.0	28Q78@1|root,2ZCQ4@2|Bacteria,1W2EV@1239|Firmicutes,24V7G@186801|Clostridia,25UED@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_157103_11	1444306.JFZC01000099_gene1162	8.385e-31	134.0	COG3103@1|root,COG3807@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,1V4UU@1239|Firmicutes,4HK14@91061|Bacilli	91061|Bacilli	MT	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23,SH3_3
HKD1_k127_157103_1	1476973.JMMB01000007_gene1293	0.0	1178.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,25QE6@186804|Peptostreptococcaceae	186801|Clostridia	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HKD1_k127_157103_2	272563.CD630_21180	1.173e-227	715.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,25QR7@186804|Peptostreptococcaceae	186801|Clostridia	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
HKD1_k127_157103_9	272563.CD630_21190	4.647e-64	221.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,25SDN@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
HKD1_k127_158601_0	1476973.JMMB01000007_gene536	0.0	1033.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25QMH@186804|Peptostreptococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
HKD1_k127_158601_2	1476973.JMMB01000007_gene535	2.591e-96	318.0	2ADW4@1|root,31EF6@2|Bacteria,1UEVS@1239|Firmicutes,25JVA@186801|Clostridia,25TJA@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
HKD1_k127_158601_1	1476973.JMMB01000007_gene534	5.007e-293	905.0	COG0857@1|root,COG1227@1|root,COG0857@2|Bacteria,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,25R22@186804|Peptostreptococcaceae	186801|Clostridia	C	DHHA2	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
HKD1_k127_159110_1	445335.CBN_2381	0.00011	53.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,36DDP@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HKD1_k127_1904283_40	1301100.HG529407_gene253	2.501e-24	102.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,36DG6@31979|Clostridiaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
HKD1_k127_1904283_5	1476973.JMMB01000007_gene600	0.0	1094.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,25T1I@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF4080)	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
HKD1_k127_1904283_37	1476973.JMMB01000007_gene599	7.185e-32	124.0	2E5P9@1|root,330DZ@2|Bacteria,1VFDT@1239|Firmicutes,24SYS@186801|Clostridia,25TWH@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1904283_21	1476973.JMMB01000007_gene598	5.084e-159	507.0	COG1397@1|root,COG1397@2|Bacteria,1VS0P@1239|Firmicutes,25J48@186801|Clostridia,25QSH@186804|Peptostreptococcaceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_1904283_6	1476973.JMMB01000007_gene597	0.0	1083.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25QY6@186804|Peptostreptococcaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HKD1_k127_1904283_34	1476973.JMMB01000007_gene596	2.185e-75	254.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,24JD2@186801|Clostridia,25RKG@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
HKD1_k127_1904283_2	1476973.JMMB01000007_gene595	0.0	1378.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,25QHB@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HKD1_k127_1904283_9	1476973.JMMB01000007_gene594	4.002e-266	824.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,25QIZ@186804|Peptostreptococcaceae	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_1904283_36	1391646.AVSU01000060_gene1099	5.488e-66	226.0	COG1433@1|root,COG1433@2|Bacteria,1VW1T@1239|Firmicutes,24KHS@186801|Clostridia,25RHP@186804|Peptostreptococcaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Nitro_FeMo-Co
HKD1_k127_1904283_39	1499684.CCNP01000018_gene1400	3.196e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,1VINN@1239|Firmicutes,24S2F@186801|Clostridia,36MCA@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
HKD1_k127_1904283_12	1476973.JMMB01000007_gene587	2.687e-204	640.0	COG1396@1|root,COG1396@2|Bacteria,1VT9K@1239|Firmicutes,25BAY@186801|Clostridia,25S1H@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
HKD1_k127_1904283_28	1301100.HG529407_gene269	3.566e-99	326.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,36ECV@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
HKD1_k127_1904283_0	1476973.JMMB01000007_gene585	0.0	1452.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,25QXR@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
HKD1_k127_1904283_32	1476973.JMMB01000007_gene584	3.294e-84	284.0	COG3027@1|root,COG3027@2|Bacteria,1VV17@1239|Firmicutes,259GQ@186801|Clostridia,25RI6@186804|Peptostreptococcaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HKD1_k127_1904283_1	1301100.HG529407_gene272	0.0	1427.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,36DSY@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
HKD1_k127_1904283_11	1301100.HG529407_gene273	2.772e-209	651.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,36DSH@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HKD1_k127_1904283_22	1476973.JMMB01000007_gene581	1.827e-148	472.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25RAX@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD1_k127_1904283_23	1476973.JMMB01000007_gene580	2.801e-135	432.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25R8D@186804|Peptostreptococcaceae	186801|Clostridia	P	TrkA N-terminal domain protein	ktrC	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HKD1_k127_1904283_10	1476973.JMMB01000007_gene579	4.444e-229	715.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25QRF@186804|Peptostreptococcaceae	186801|Clostridia	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HKD1_k127_1904283_35	1476973.JMMB01000007_gene578	5.079e-66	226.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,25RKJ@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HKD1_k127_1904283_38	1476973.JMMB01000007_gene577	3.805e-30	119.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25RWU@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HKD1_k127_1904283_27	1476973.JMMB01000007_gene576	1.07e-102	334.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,25RBJ@186804|Peptostreptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HKD1_k127_1904283_8	1476973.JMMB01000007_gene575	4.231e-288	887.0	COG0465@1|root,COG0465@2|Bacteria,1TRV4@1239|Firmicutes,24C3E@186801|Clostridia,25R3S@186804|Peptostreptococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
HKD1_k127_1904283_4	1476973.JMMB01000007_gene574	0.0	1247.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25QSG@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HKD1_k127_1904283_29	1476973.JMMB01000007_gene573	1.978e-96	319.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,25RFE@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HKD1_k127_1904283_25	1476973.JMMB01000007_gene572	3.221e-114	374.0	2AZZM@1|root,31S9P@2|Bacteria,1V6WH@1239|Firmicutes,2490E@186801|Clostridia,25RHE@186804|Peptostreptococcaceae	186801|Clostridia	S	YtxC-like family	ytxC	-	-	-	-	-	-	-	-	-	-	-	YtxC
HKD1_k127_1904283_14	1476973.JMMB01000007_gene571	2.238e-183	575.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25R77@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD1_k127_1904283_24	1511.CLOST_1120	5.994e-134	436.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25QBZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	rbsC	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HKD1_k127_1904283_7	1476973.JMMB01000007_gene569	1.079e-309	952.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25QC2@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	rbsA2	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HKD1_k127_1904283_16	1476973.JMMB01000007_gene568	2.163e-180	569.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,25S1Q@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HKD1_k127_1904283_18	1476973.JMMB01000007_gene567	1.97e-163	516.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25RC8@186804|Peptostreptococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_1904283_30	1301100.HG529407_gene289	2.598e-96	316.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,36I1E@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HKD1_k127_1904283_15	1476973.JMMB01000007_gene565	6.053e-183	582.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25QDU@186804|Peptostreptococcaceae	186801|Clostridia	V	G5	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HKD1_k127_1904283_26	1476973.JMMB01000007_gene564	5.17e-114	370.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,25R3J@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HKD1_k127_1904283_3	1476973.JMMB01000007_gene563	0.0	1296.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,25QK9@186804|Peptostreptococcaceae	186801|Clostridia	O	AAA domain	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
HKD1_k127_1904283_17	1476973.JMMB01000007_gene562	5.309e-164	521.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,25R2C@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF1730)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
HKD1_k127_1904283_33	1476973.JMMB01000007_gene561	1.974e-78	263.0	COG4570@1|root,COG4570@2|Bacteria,1V2AT@1239|Firmicutes,24C87@186801|Clostridia,25RCB@186804|Peptostreptococcaceae	186801|Clostridia	L	Endodeoxyribonuclease RusA	rusA	-	-	-	-	-	-	-	-	-	-	-	RusA
HKD1_k127_1904283_19	1476973.JMMB01000007_gene559	6.249e-162	511.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,25SGH@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HKD1_k127_1904283_31	1476973.JMMB01000007_gene558	1.215e-91	304.0	COG0640@1|root,COG0640@2|Bacteria,1VC7T@1239|Firmicutes,24PC2@186801|Clostridia,25RG8@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD1_k127_1904283_13	1476973.JMMB01000007_gene557	1.295e-183	576.0	COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,2491K@186801|Clostridia,25S53@186804|Peptostreptococcaceae	186801|Clostridia	E	Glutaminase	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
HKD1_k127_1904283_20	1476973.JMMB01000007_gene556	8.085e-162	511.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,25QMT@186804|Peptostreptococcaceae	186801|Clostridia	FJ	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HKD1_k127_2107328_1	1408823.AXUS01000026_gene1566	0.0	1048.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia	186801|Clostridia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PrpR_N,Sigma54_activat
HKD1_k127_2107328_4	1476973.JMMB01000007_gene2915	2.39e-218	680.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,25QT9@186804|Peptostreptococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
HKD1_k127_2107328_9	1476973.JMMB01000007_gene2914	1.334e-85	286.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,25T5R@186804|Peptostreptococcaceae	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
HKD1_k127_2107328_15	1476973.JMMB01000007_gene2913	1.475e-50	182.0	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,25RYG@186804|Peptostreptococcaceae	186801|Clostridia	S	NusG domain II	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
HKD1_k127_2107328_6	1476973.JMMB01000007_gene2912	3.154e-156	499.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25QVS@186804|Peptostreptococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD1_k127_2107328_3	1476973.JMMB01000007_gene2911	3.001e-221	693.0	COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,24H65@186801|Clostridia,25S1I@186804|Peptostreptococcaceae	186801|Clostridia	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
HKD1_k127_2107328_8	1476973.JMMB01000007_gene2910	4.026e-119	390.0	COG3807@1|root,COG3807@2|Bacteria,1W2D0@1239|Firmicutes	1239|Firmicutes	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
HKD1_k127_2107328_10	1476973.JMMB01000007_gene2909	7.077e-82	288.0	2DMD0@1|root,32NCF@2|Bacteria,1V8UR@1239|Firmicutes,25EYN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2107328_12	1476973.JMMB01000007_gene2908	1.287e-73	253.0	COG1595@1|root,COG1595@2|Bacteria,1V8CD@1239|Firmicutes,24FGM@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
HKD1_k127_2107328_7	1476973.JMMB01000007_gene2907	1.86e-119	387.0	2F05B@1|root,33T8Z@2|Bacteria,1VRBI@1239|Firmicutes,24YT8@186801|Clostridia,25RKI@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2107328_13	1476973.JMMB01000007_gene2906	4.068e-72	245.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,25RJT@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HKD1_k127_2107328_17	1476973.JMMB01000007_gene2904	1.046e-20	92.0	2BF2M@1|root,328UM@2|Bacteria,1UU2W@1239|Firmicutes,255A7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2107328_5	1476973.JMMB01000007_gene2903	9.92e-198	625.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25TBM@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HKD1_k127_2107328_11	1476973.JMMB01000007_gene2901	7.15e-74	249.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,25RFW@186804|Peptostreptococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
HKD1_k127_2107328_16	1476973.JMMB01000007_gene2900	1.026e-38	146.0	COG1445@1|root,COG1445@2|Bacteria,1W2YM@1239|Firmicutes,253C1@186801|Clostridia,25U48@186804|Peptostreptococcaceae	186801|Clostridia	G	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2107328_14	1476973.JMMB01000007_gene2899	2.941e-68	234.0	COG1846@1|root,COG1846@2|Bacteria,1VFWY@1239|Firmicutes,25CQD@186801|Clostridia	186801|Clostridia	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_2107328_0	1476973.JMMB01000007_gene2898	0.0	1195.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25QDB@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_2107328_2	1301100.HG529399_gene6822	2.5e-323	996.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_2108901_24	1292035.H476_0156	1.68e-09	59.0	COG1915@1|root,COG1915@2|Bacteria,1TT91@1239|Firmicutes,24A6C@186801|Clostridia,25SWN@186804|Peptostreptococcaceae	186801|Clostridia	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2108901_0	1476973.JMMB01000007_gene1676	0.0	1053.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,25QU3@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HKD1_k127_2108901_2	1301100.HG529308_gene362	7.538e-185	581.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,36DBJ@31979|Clostridiaceae	186801|Clostridia	H	molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
HKD1_k127_2108901_16	1301100.HG529308_gene363	1.366e-72	249.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,36I3A@31979|Clostridiaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD1_k127_2108901_21	702450.CUW_1546	7.054e-26	107.0	COG3478@1|root,COG3478@2|Bacteria,1VEIV@1239|Firmicutes,3VTPX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_13
HKD1_k127_2108901_13	1476973.JMMB01000007_gene1671	1.738e-84	285.0	COG1192@1|root,COG1192@2|Bacteria,1UI78@1239|Firmicutes,25ECF@186801|Clostridia,25TEE@186804|Peptostreptococcaceae	186801|Clostridia	D	Involved in chromosome partitioning	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2108901_10	1476973.JMMB01000007_gene1670	1.035e-112	368.0	COG0206@1|root,COG0206@2|Bacteria,1VW0D@1239|Firmicutes,2517U@186801|Clostridia,25TBF@186804|Peptostreptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C
HKD1_k127_2108901_15	1476973.JMMB01000007_gene1669	3.964e-80	269.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,25RIQ@186804|Peptostreptococcaceae	186801|Clostridia	S	QueT transporter	-	-	-	-	-	-	-	-	-	-	-	-	QueT
HKD1_k127_2108901_11	1476973.JMMB01000007_gene1668	1.114e-91	304.0	COG0558@1|root,COG0558@2|Bacteria,1V33A@1239|Firmicutes,24G6W@186801|Clostridia,25TDP@186804|Peptostreptococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
HKD1_k127_2108901_17	1301100.HG529399_gene6831	3.272e-72	249.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,24IF0@186801|Clostridia,36VSJ@31979|Clostridiaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_2108901_6	1476973.JMMB01000007_gene1666	3.491e-143	457.0	COG0247@1|root,COG0247@2|Bacteria,1UYKK@1239|Firmicutes,25E5V@186801|Clostridia,25RZS@186804|Peptostreptococcaceae	186801|Clostridia	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_17,Fer4_8
HKD1_k127_2108901_8	1476973.JMMB01000007_gene1665	9.758e-118	382.0	COG0398@1|root,COG0398@2|Bacteria,1TRFC@1239|Firmicutes,24CYX@186801|Clostridia,25SZC@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_2108901_3	1476973.JMMB01000007_gene1664	1.78e-168	533.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24AGI@186801|Clostridia,25SGX@186804|Peptostreptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD1_k127_2108901_14	1151292.QEW_2350	1.219e-83	279.0	COG4766@1|root,COG4766@2|Bacteria,1V498@1239|Firmicutes,25DES@186801|Clostridia	186801|Clostridia	E	ethanolamine	-	-	-	ko:K04030	-	-	-	-	ko00000	-	-	-	EutQ
HKD1_k127_2108901_1	1476973.JMMB01000007_gene1662	4.7e-215	670.0	COG3192@1|root,COG3192@2|Bacteria,1TNZF@1239|Firmicutes,2483P@186801|Clostridia,25SSV@186804|Peptostreptococcaceae	186801|Clostridia	E	Ethanolamine utilisation protein, EutH	eutH	-	-	ko:K04023	-	-	-	-	ko00000	-	-	-	EutH
HKD1_k127_2108901_12	1476973.JMMB01000007_gene1661	1.637e-90	300.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25TA1@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD1_k127_2108901_19	195103.CPF_0900	9.296e-35	134.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,36N12@31979|Clostridiaceae	186801|Clostridia	CQ	Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
HKD1_k127_2108901_9	1476973.JMMB01000007_gene1659	7.75e-113	366.0	2E7RK@1|root,3326X@2|Bacteria,1VEHH@1239|Firmicutes,24JHV@186801|Clostridia,25S84@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2108901_7	1476973.JMMB01000007_gene1658	5.365e-121	390.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,25S6W@186804|Peptostreptococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	-	-	-	-	-	-	-	-	-	-	PTAC
HKD1_k127_2108901_5	1476973.JMMB01000007_gene1657	4.279e-151	479.0	COG4812@1|root,COG4812@2|Bacteria,1V18U@1239|Firmicutes,24D11@186801|Clostridia,25SVN@186804|Peptostreptococcaceae	186801|Clostridia	E	Cobalamin adenosyltransferase	eutT	-	2.5.1.17	ko:K04032	ko00860,ko01100,map00860,map01100	-	R01492	RC00533	ko00000,ko00001,ko01000	-	-	-	Cob_adeno_trans
HKD1_k127_2108901_18	1476973.JMMB01000007_gene1656	1.051e-47	172.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25TMQ@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC domain	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
HKD1_k127_2108901_4	1476973.JMMB01000007_gene1655	5.083e-159	503.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,25S35@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HKD1_k127_2154531_0	1476973.JMMB01000007_gene818	0.0	1474.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25QC0@186804|Peptostreptococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD1_k127_2154531_2	1476973.JMMB01000007_gene819	0.0	1177.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,25QCE@186804|Peptostreptococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
HKD1_k127_2154531_30	1301100.HG529229_gene5390	2.365e-144	461.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,36E2H@31979|Clostridiaceae	186801|Clostridia	K	transcriptional antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
HKD1_k127_2154531_45	1476973.JMMB01000007_gene822	6.12e-80	268.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,24N5U@186801|Clostridia,25TIA@186804|Peptostreptococcaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	crr	-	2.7.1.199	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806,M00809	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1
HKD1_k127_2154531_3	1292035.H476_0360	7.405e-306	942.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,25QI1@186804|Peptostreptococcaceae	186801|Clostridia	G	pts system	ptsG-BC	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HKD1_k127_2154531_38	1292035.H476_2053	2.346e-109	360.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,25S8V@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HKD1_k127_2154531_52	1151292.QEW_3211	1.032e-05	50.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HKD1_k127_2154531_14	272563.CD630_26640	1.719e-243	759.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,25QE5@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_2154531_13	1301100.HG529229_gene5392	5.426e-257	793.0	COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,248Y0@186801|Clostridia,36GRR@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	6.3.1.12	ko:K17810	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD1_k127_2154531_34	1476973.JMMB01000007_gene825	1.833e-133	427.0	COG1794@1|root,COG1794@2|Bacteria,1TQ6M@1239|Firmicutes,25CFU@186801|Clostridia,25QIM@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
HKD1_k127_2154531_6	1476973.JMMB01000007_gene826	6.691e-288	887.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,25QYF@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_2154531_5	1476973.JMMB01000007_gene827	3.518e-289	894.0	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia,25S69@186804|Peptostreptococcaceae	186801|Clostridia	T	5TMR of 5TMR-LYT	-	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
HKD1_k127_2154531_37	1476973.JMMB01000007_gene828	1.207e-121	394.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,25RZN@186804|Peptostreptococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
HKD1_k127_2154531_7	1476973.JMMB01000007_gene829	7.488e-281	867.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25QTF@186804|Peptostreptococcaceae	186801|Clostridia	T	Carbon starvation protein CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
HKD1_k127_2154531_21	1391646.AVSU01000092_gene409	9.538e-218	678.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25QQJ@186804|Peptostreptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HKD1_k127_2154531_25	1301100.HG529229_gene5401	5.095e-185	584.0	28SRE@1|root,2ZF1B@2|Bacteria,1W33E@1239|Firmicutes,24W3Z@186801|Clostridia,36PKN@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CbiX,Ferrochelatase
HKD1_k127_2154531_16	1476973.JMMB01000007_gene836	3.886e-241	748.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,25R2M@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
HKD1_k127_2154531_11	1476973.JMMB01000007_gene837	1.623e-259	802.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25R6R@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HKD1_k127_2154531_28	1476973.JMMB01000007_gene838	1.268e-150	477.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25QZI@186804|Peptostreptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HKD1_k127_2154531_24	1476973.JMMB01000007_gene839	5.262e-188	589.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25QND@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HKD1_k127_2154531_49	1476973.JMMB01000007_gene855	1.052e-43	162.0	2EMIU@1|root,33F7E@2|Bacteria,1W5VZ@1239|Firmicutes,25925@186801|Clostridia,25S00@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2154531_1	1476973.JMMB01000007_gene856	0.0	1215.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25R3P@186804|Peptostreptococcaceae	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HKD1_k127_2154531_15	1476973.JMMB01000007_gene857	1.63e-242	754.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,25QJG@186804|Peptostreptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_2154531_26	1476973.JMMB01000007_gene858	5.957e-185	581.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,25QYZ@186804|Peptostreptococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HKD1_k127_2154531_10	1476973.JMMB01000007_gene859	1.116e-261	809.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,25QXT@186804|Peptostreptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD1_k127_2154531_22	1301100.HG529229_gene5416	3.894e-201	630.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HKD1_k127_2154531_19	1301100.HG529229_gene5417	8.24e-229	712.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,36E84@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HKD1_k127_2154531_17	1301100.HG529229_gene5418	2.207e-237	738.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,36DC0@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the EPSP synthase family. MurA subfamily	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HKD1_k127_2154531_39	1476973.JMMB01000007_gene863	3.954e-106	350.0	COG1589@1|root,COG1589@2|Bacteria,1UFWJ@1239|Firmicutes,25MVM@186801|Clostridia,25RQ2@186804|Peptostreptococcaceae	186801|Clostridia	D	Essential cell division protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HKD1_k127_2154531_40	1476973.JMMB01000007_gene864	2.041e-100	332.0	COG3879@1|root,COG3879@2|Bacteria,1V91C@1239|Firmicutes,25DHT@186801|Clostridia,25SDY@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
HKD1_k127_2154531_41	1476973.JMMB01000007_gene865	2.336e-100	331.0	COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,24DRC@186801|Clostridia,25SZ2@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
HKD1_k127_2154531_46	1476973.JMMB01000007_gene866	1.201e-61	213.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,24N58@186801|Clostridia,25TFI@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
HKD1_k127_2154531_20	1476973.JMMB01000007_gene867	1.495e-222	692.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,25QCR@186804|Peptostreptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HKD1_k127_2154531_29	1476973.JMMB01000007_gene868	9.882e-148	471.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,25QNJ@186804|Peptostreptococcaceae	186801|Clostridia	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
HKD1_k127_2154531_33	1476973.JMMB01000007_gene869	3.373e-135	432.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,25STU@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD1_k127_2154531_27	1301100.HG529229_gene5426	2.49e-154	489.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,36E0E@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_2154531_47	1476973.JMMB01000007_gene871	3.273e-48	177.0	29YU2@1|root,30KQE@2|Bacteria,1VQDK@1239|Firmicutes,25JY8@186801|Clostridia,25U4P@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2154531_44	1476973.JMMB01000007_gene872	7.631e-82	277.0	COG4512@1|root,COG4512@2|Bacteria,1VF1N@1239|Firmicutes,24SCM@186801|Clostridia,25TSE@186804|Peptostreptococcaceae	186801|Clostridia	KOT	Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
HKD1_k127_2154531_9	1476973.JMMB01000007_gene874	7.326e-277	859.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,25SWH@186804|Peptostreptococcaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5
HKD1_k127_2154531_48	1476973.JMMB01000007_gene875	1.158e-47	171.0	COG1873@1|root,COG1873@2|Bacteria,1UEEI@1239|Firmicutes,25JAV@186801|Clostridia,25RSR@186804|Peptostreptococcaceae	186801|Clostridia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
HKD1_k127_2154531_43	1476973.JMMB01000007_gene876	2.422e-89	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,25R8K@186804|Peptostreptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HKD1_k127_2154531_36	1476973.JMMB01000007_gene877	8.413e-131	419.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,25R9Q@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HKD1_k127_2154531_35	1476973.JMMB01000007_gene878	2.684e-131	420.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,25QP7@186804|Peptostreptococcaceae	186801|Clostridia	K	response regulator	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_2154531_18	1476973.JMMB01000007_gene879	7.264e-229	713.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25QXW@186804|Peptostreptococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR2	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
HKD1_k127_2154531_32	1301100.HG529230_gene5338	8.126e-140	450.0	28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,24A0W@186801|Clostridia,36FYB@31979|Clostridiaceae	186801|Clostridia	S	YIEGIA protein	-	-	-	ko:K05739	-	-	-	-	ko00000	-	-	-	YIEGIA
HKD1_k127_2154531_31	1301100.HG529230_gene5339	4.745e-140	450.0	28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,24A0W@186801|Clostridia,36FYB@31979|Clostridiaceae	186801|Clostridia	S	YIEGIA protein	-	-	-	ko:K05739	-	-	-	-	ko00000	-	-	-	YIEGIA
HKD1_k127_2154531_50	1301100.HG529230_gene5340	1.037e-31	124.0	2EI9Q@1|root,33C12@2|Bacteria,1VK6T@1239|Firmicutes,24UZ6@186801|Clostridia,36NTI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2154531_12	1476973.JMMB01000007_gene883	2.21e-258	799.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25SXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
HKD1_k127_2154531_8	1476973.JMMB01000007_gene884	2.278e-278	857.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,25R13@186804|Peptostreptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HKD1_k127_2154531_42	1301100.HG529230_gene5343	2.268e-97	321.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,36IPV@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HKD1_k127_2154531_23	1476973.JMMB01000007_gene886	3.861e-198	619.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,25QDE@186804|Peptostreptococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HKD1_k127_2154531_4	1301100.HG529230_gene5345	1.131e-291	898.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,36DMZ@31979|Clostridiaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HKD1_k127_2199707_9	1476973.JMMB01000007_gene1326	3.666e-103	338.0	COG2230@1|root,COG2230@2|Bacteria,1V4JG@1239|Firmicutes,24II2@186801|Clostridia,25RFK@186804|Peptostreptococcaceae	186801|Clostridia	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DOT1,Methyltransf_32
HKD1_k127_2199707_8	1476973.JMMB01000007_gene1323	2.945e-153	488.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,25SKI@186804|Peptostreptococcaceae	186801|Clostridia	P	Periplasmic binding protein	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HKD1_k127_2199707_6	1476973.JMMB01000007_gene1325	9.243e-171	542.0	COG0392@1|root,COG0392@2|Bacteria,1TV0P@1239|Firmicutes,24DYR@186801|Clostridia,25S2Q@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HKD1_k127_2199707_5	1301100.HG529285_gene7049	2.535e-174	550.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,36DD8@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HKD1_k127_2199707_2	1476973.JMMB01000007_gene1321	3.303e-213	666.0	COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,249Z4@186801|Clostridia,25S0W@186804|Peptostreptococcaceae	186801|Clostridia	JKL	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
HKD1_k127_2199707_7	1476973.JMMB01000007_gene1320	2.412e-165	522.0	2BYY4@1|root,2Z80Y@2|Bacteria,1TSXF@1239|Firmicutes,24B6G@186801|Clostridia,25T1J@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4438)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4438
HKD1_k127_2199707_13	1476973.JMMB01000007_gene2325	2.55e-59	207.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24VHG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2199707_0	1476973.JMMB01000007_gene1319	2.475e-229	715.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,25SAJ@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_2199707_4	1292035.H476_2389	5.374e-196	620.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,25T4G@186804|Peptostreptococcaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HKD1_k127_2199707_16	1476973.JMMB01000007_gene1317	7.601e-24	102.0	2967E@1|root,2ZTHG@2|Bacteria,1W42D@1239|Firmicutes,256WV@186801|Clostridia,25U8G@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2199707_10	1476973.JMMB01000007_gene1316	5.976e-73	248.0	COG0701@1|root,COG0701@2|Bacteria,1V5T4@1239|Firmicutes,24HM7@186801|Clostridia,25TJP@186804|Peptostreptococcaceae	186801|Clostridia	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
HKD1_k127_2199707_12	1391646.AVSU01000116_gene798	5.188e-70	242.0	COG0701@1|root,COG0701@2|Bacteria,1V49V@1239|Firmicutes,24FRM@186801|Clostridia,25TIK@186804|Peptostreptococcaceae	186801|Clostridia	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
HKD1_k127_2199707_1	1476973.JMMB01000007_gene1312	9.668e-221	689.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25QUB@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K18345	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_2199707_14	877424.ATWC01000014_gene2556	9.368e-57	206.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia,27K6R@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_2199707_3	1151292.QEW_1998	1.763e-197	621.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25QNA@186804|Peptostreptococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HKD1_k127_2199707_18	1151292.QEW_1376	1.861e-16	84.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,25R6F@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_2199707_17	272563.CD630_09940	1.653e-19	89.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,25R6F@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_2199707_11	857293.CAAU_1331	4.124e-70	244.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,36IDY@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HKD1_k127_2199707_15	1391646.AVSU01000115_gene910	1.636e-35	135.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,25QDF@186804|Peptostreptococcaceae	186801|Clostridia	P	Copper-exporting ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_2199888_19	1280692.AUJL01000005_gene1783	0.0004217	42.0	COG2963@1|root,COG2963@2|Bacteria,1V09A@1239|Firmicutes,24G3Z@186801|Clostridia,36P7N@31979|Clostridiaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
HKD1_k127_2199888_12	1476973.JMMB01000007_gene625	4.756e-53	198.0	COG3266@1|root,COG3266@2|Bacteria,1UEWK@1239|Firmicutes,25JW1@186801|Clostridia,25TMN@186804|Peptostreptococcaceae	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2199888_17	272563.CD630_31580	7.364e-16	80.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,25SWR@186804|Peptostreptococcaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD1_k127_2199888_0	1476973.JMMB01000007_gene1975	0.0	1596.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,25QVT@186804|Peptostreptococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HKD1_k127_2199888_1	1476973.JMMB01000007_gene1974	0.0	1056.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25R29@186804|Peptostreptococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HKD1_k127_2199888_4	1476973.JMMB01000007_gene1973	5.185e-174	548.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25QWB@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HKD1_k127_2199888_15	1476973.JMMB01000007_gene1972	1.852e-41	153.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,24QIM@186801|Clostridia,25TNG@186804|Peptostreptococcaceae	186801|Clostridia	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
HKD1_k127_2199888_18	1301100.HG529253_gene6308	8.611e-15	83.0	2BDS0@1|root,327FR@2|Bacteria,1UTBU@1239|Firmicutes,252AX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2199888_14	1391646.AVSU01000038_gene1969	1.304e-49	178.0	2E6A2@1|root,3182Z@2|Bacteria,1V931@1239|Firmicutes,25JW0@186801|Clostridia,25TMK@186804|Peptostreptococcaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HKD1_k127_2199888_2	1476973.JMMB01000007_gene1855	0.0	1038.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,25QKV@186804|Peptostreptococcaceae	186801|Clostridia	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD1_k127_2199888_8	1476973.JMMB01000007_gene1971	3.418e-87	290.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,25RP7@186804|Peptostreptococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
HKD1_k127_2199888_7	1476973.JMMB01000007_gene1970	1.041e-87	293.0	2A1RE@1|root,30PZZ@2|Bacteria,1V46H@1239|Firmicutes,24FU8@186801|Clostridia,25SXF@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	-
HKD1_k127_2199888_6	1476973.JMMB01000007_gene1322	8.267e-142	454.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25S8A@186804|Peptostreptococcaceae	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HKD1_k127_2199888_3	1476973.JMMB01000007_gene1968	4.241e-269	829.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25R6P@186804|Peptostreptococcaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HKD1_k127_2199888_5	1476973.JMMB01000007_gene2147	1.537e-147	470.0	arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,248EN@186801|Clostridia,25TKD@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
HKD1_k127_2199888_10	1476973.JMMB01000007_gene1966	1.267e-68	233.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,25S1U@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
HKD1_k127_2199888_13	1301100.HG529362_gene2098	1.007e-52	195.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Alginate_lyase,BNR_2,Exo_endo_phos,F5_F8_type_C,Laminin_G_3,Metallophos,PA14,SASA,SLH
HKD1_k127_226738_0	1196322.A370_01794	5.759e-287	884.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	apu	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77,Malt_amylase_C
HKD1_k127_226738_1	1196322.A370_01795	2.373e-245	759.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD1_k127_243659_11	1321778.HMPREF1982_00773	3.072e-95	326.0	COG0419@1|root,COG0419@2|Bacteria,1TTBF@1239|Firmicutes,24CKY@186801|Clostridia	186801|Clostridia	L	DNA sulfur modification protein DndD	-	-	-	ko:K19171	-	-	-	-	ko00000,ko02048	-	-	-	AAA_23
HKD1_k127_243659_6	929506.CbC4_2080	2.032e-145	475.0	COG0175@1|root,COG0175@2|Bacteria,1TPR6@1239|Firmicutes,24ABC@186801|Clostridia,36QZ6@31979|Clostridiaceae	186801|Clostridia	EH	Sulfurtransferase DndC	-	-	-	ko:K19170	-	-	-	-	ko00000,ko02048	-	-	-	PAPS_reduct
HKD1_k127_243659_16	1301100.HG529274_gene1743	1.605e-69	236.0	COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,24JZG@186801|Clostridia,36J8W@31979|Clostridiaceae	186801|Clostridia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	-	-	-	-	-	-	-	-	-	HIT
HKD1_k127_243659_10	1292035.H476_1244	1.273e-96	323.0	COG0551@1|root,COG0551@2|Bacteria,1V93W@1239|Firmicutes,24CEN@186801|Clostridia,25TS7@186804|Peptostreptococcaceae	186801|Clostridia	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
HKD1_k127_243659_15	1443122.Z958_08595	1.317e-74	261.0	COG0272@1|root,COG0847@1|root,COG0272@2|Bacteria,COG0847@2|Bacteria,1V57H@1239|Firmicutes,24CWP@186801|Clostridia,36WQD@31979|Clostridiaceae	186801|Clostridia	L	3' exoribonuclease, RNase T-like	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
HKD1_k127_243659_9	1476973.JMMB01000007_gene1697	2.247e-108	356.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,25R8T@186804|Peptostreptococcaceae	186801|Clostridia	ET	ABC transporter substrate-binding protein	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD1_k127_243659_13	1476973.JMMB01000007_gene1698	1.349e-85	287.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,25RCK@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD1_k127_243659_8	1476973.JMMB01000007_gene1699	4.525e-113	367.0	COG1126@1|root,COG1126@2|Bacteria,1UZAN@1239|Firmicutes,24AWF@186801|Clostridia,25R0N@186804|Peptostreptococcaceae	186801|Clostridia	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HKD1_k127_243659_17	1476973.JMMB01000007_gene1472	1.139e-36	139.0	COG1905@1|root,COG1905@2|Bacteria,1VFEK@1239|Firmicutes,24QMM@186801|Clostridia	186801|Clostridia	C	NADH ubiquinone oxidoreductase 24 kD subunit	fhmD	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
HKD1_k127_243659_0	1476973.JMMB01000007_gene1473	4.156e-288	893.0	COG1145@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,25KCE@186801|Clostridia,25SAF@186804|Peptostreptococcaceae	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4
HKD1_k127_243659_1	1476973.JMMB01000007_gene1474	3.042e-219	683.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,25QXE@186804|Peptostreptococcaceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
HKD1_k127_243659_21	1031288.AXAA01000009_gene667	2.423e-08	58.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,36KJQ@31979|Clostridiaceae	186801|Clostridia	G	HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HKD1_k127_243659_14	1033737.CAEV01000099_gene1658	3.36e-80	272.0	COG0778@1|root,COG0778@2|Bacteria,1V1BQ@1239|Firmicutes,25B0F@186801|Clostridia,36WK9@31979|Clostridiaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD1_k127_243659_2	1499683.CCFF01000014_gene4063	2.302e-217	679.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,36EQY@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7
HKD1_k127_243659_5	1476973.JMMB01000007_gene2002	4.936e-152	483.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25QJW@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD1_k127_243659_4	1476973.JMMB01000007_gene2001	1.273e-179	565.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25QQ5@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD1_k127_243659_7	1499683.CCFF01000014_gene3612	3.882e-126	408.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,36F84@31979|Clostridiaceae	186801|Clostridia	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	nit	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
HKD1_k127_243659_12	1301100.HG529408_gene225	2.686e-88	296.0	28JAU@1|root,33RGI@2|Bacteria,1VSTV@1239|Firmicutes,25D98@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_243659_3	1499683.CCFF01000015_gene3279	3.326e-207	666.0	COG2199@1|root,COG3706@2|Bacteria,1V6MC@1239|Firmicutes,24JED@186801|Clostridia,36KXT@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12,TPR_7,TPR_8
HKD1_k127_243659_19	1476973.JMMB01000007_gene2518	6.252e-28	113.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,24QNU@186801|Clostridia,25TX7@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
HKD1_k127_243659_20	1476973.JMMB01000007_gene1859	9.973e-20	88.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25TZ4@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_2567078_39	1476973.JMMB01000007_gene2831	5.172e-91	303.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25TE6@186804|Peptostreptococcaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
HKD1_k127_2567078_16	1476973.JMMB01000007_gene2832	4.621e-203	634.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25R00@186804|Peptostreptococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
HKD1_k127_2567078_29	1301100.HG529429_gene1881	6.51e-136	436.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,36UH9@31979|Clostridiaceae	186801|Clostridia	P	spermidine putrescine transport system, permease	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HKD1_k127_2567078_26	1476973.JMMB01000007_gene2834	3.637e-154	489.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,25QQU@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HKD1_k127_2567078_17	1476973.JMMB01000007_gene2835	8.137e-201	627.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25QEJ@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
HKD1_k127_2567078_36	1301100.HG529429_gene1884	4.669e-115	372.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,36F4A@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
HKD1_k127_2567078_24	1476973.JMMB01000007_gene2846	5.801e-169	532.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,25QXF@186804|Peptostreptococcaceae	186801|Clostridia	S	S1 domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
HKD1_k127_2567078_14	1301100.HG529429_gene1904	9.556e-210	657.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,36DTC@31979|Clostridiaceae	186801|Clostridia	C	malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HKD1_k127_2567078_43	1045858.Bint_0395	2.67e-63	222.0	COG1838@1|root,COG1838@2|Bacteria,2J7NU@203691|Spirochaetes	203691|Spirochaetes	C	Fumarate	fumB	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
HKD1_k127_2567078_28	1301100.HG529429_gene1906	1.975e-149	476.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,36DM3@31979|Clostridiaceae	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
HKD1_k127_2567078_50	1476973.JMMB01000007_gene2847	3.774e-24	103.0	COG2155@1|root,COG2155@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HKD1_k127_2567078_40	1476973.JMMB01000007_gene2848	1.42e-76	258.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,25RJN@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HKD1_k127_2567078_5	1301100.HG529429_gene1908	0.0	1042.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36EQ0@31979|Clostridiaceae	186801|Clostridia	E	peptidase M24	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
HKD1_k127_2567078_41	1292035.H476_0512	5.921e-76	262.0	COG1116@1|root,COG1116@2|Bacteria,1V7QX@1239|Firmicutes,24H9Z@186801|Clostridia	186801|Clostridia	P	Abc transporter	ssuB1	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD1_k127_2567078_35	1476973.JMMB01000007_gene2851	2.076e-115	377.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,25SPT@186804|Peptostreptococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
HKD1_k127_2567078_27	1476973.JMMB01000007_gene2852	5.38e-150	480.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,25S77@186804|Peptostreptococcaceae	186801|Clostridia	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
HKD1_k127_2567078_2	1476973.JMMB01000007_gene2853	0.0	1193.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,25T1E@186804|Peptostreptococcaceae	186801|Clostridia	C	Radical SAM N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
HKD1_k127_2567078_21	272563.CD630_09960	3.971e-189	598.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,25QVX@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HKD1_k127_2567078_31	1151292.QEW_1377	1.141e-132	429.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25QHY@186804|Peptostreptococcaceae	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD1_k127_2567078_19	272563.CD630_09940	7.149e-198	621.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,25R6F@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_2567078_52	1301100.HG529430_gene1925	8.874e-05	46.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,24HWD@186801|Clostridia,36RQ6@31979|Clostridiaceae	186801|Clostridia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD1_k127_2567078_30	1476973.JMMB01000007_gene2855	9.527e-135	431.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,25S4P@186804|Peptostreptococcaceae	186801|Clostridia	E	DNA polymerase alpha chain like domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
HKD1_k127_2567078_10	1476973.JMMB01000007_gene2856	1.312e-239	745.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,25QZC@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal protein S1	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
HKD1_k127_2567078_34	1301100.HG529430_gene1928	4.913e-117	379.0	COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,24A0M@186801|Clostridia,36DDK@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
HKD1_k127_2567078_51	1476973.JMMB01000007_gene2857	1.446e-11	66.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25QCC@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_2567078_53	1123511.KB905855_gene2008	0.0001172	44.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_3	1301100.HG529430_gene1929	0.0	1084.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,36DDU@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
HKD1_k127_2567078_37	1476973.JMMB01000007_gene2859	2.334e-107	351.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,25RE9@186804|Peptostreptococcaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_2567078_15	1476973.JMMB01000007_gene2862	6.848e-205	640.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,25QTK@186804|Peptostreptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HKD1_k127_2567078_8	1476973.JMMB01000007_gene2863	8.409e-313	960.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,25QZV@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
HKD1_k127_2567078_49	1476973.JMMB01000007_gene2864	2.465e-30	120.0	2CK5R@1|root,30EWS@2|Bacteria,1UD2Y@1239|Firmicutes,25K1M@186801|Clostridia,25U5I@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_7	1476973.JMMB01000007_gene2867	8.25e-322	989.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25QUJ@186804|Peptostreptococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD1_k127_2567078_47	1476973.JMMB01000007_gene2870	2.057e-46	169.0	29UP6@1|root,30G0S@2|Bacteria,1UEZI@1239|Firmicutes,254DT@186801|Clostridia,25U0Y@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_25	1476973.JMMB01000007_gene2871	1.633e-154	491.0	29UFU@1|root,30FSR@2|Bacteria,1UEJZ@1239|Firmicutes,24Z7T@186801|Clostridia,25SNV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_20	1476973.JMMB01000007_gene2872	9.423e-194	608.0	COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,24A88@186801|Clostridia,25SP9@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_12	1476973.JMMB01000007_gene2873	1.461e-231	721.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25QFG@186804|Peptostreptococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HKD1_k127_2567078_48	1476973.JMMB01000007_gene2874	2.685e-44	166.0	COG0629@1|root,COG0629@2|Bacteria,1UEZM@1239|Firmicutes,25JZT@186801|Clostridia,25U14@186804|Peptostreptococcaceae	186801|Clostridia	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD1_k127_2567078_4	1476973.JMMB01000007_gene2875	0.0	1052.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,25QER@186804|Peptostreptococcaceae	186801|Clostridia	G	Alpha-amylase domain	apu	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77,Malt_amylase_C
HKD1_k127_2567078_0	1476973.JMMB01000007_gene2876	0.0	1390.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25QJN@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HKD1_k127_2567078_9	1476973.JMMB01000007_gene2877	1.963e-282	871.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25R7P@186804|Peptostreptococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HKD1_k127_2567078_13	1476973.JMMB01000007_gene2878	9.965e-211	658.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25QUP@186804|Peptostreptococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD1_k127_2567078_11	1476973.JMMB01000007_gene2879	1.171e-231	719.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,25QNV@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HKD1_k127_2567078_1	1476973.JMMB01000007_gene2880	0.0	1268.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25QUV@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HKD1_k127_2567078_23	1476973.JMMB01000007_gene2881	2.979e-182	573.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25R71@186804|Peptostreptococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
HKD1_k127_2567078_45	1476973.JMMB01000007_gene2882	1.194e-53	192.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,25JA9@186801|Clostridia,25RPI@186804|Peptostreptococcaceae	186801|Clostridia	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
HKD1_k127_2567078_38	1476973.JMMB01000007_gene2883	1.384e-96	319.0	2BGVG@1|root,32AV7@2|Bacteria,1UGRN@1239|Firmicutes,24YFI@186801|Clostridia,25TER@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567078_33	997296.PB1_02875	1.274e-124	406.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus	91061|Bacilli	E	Belongs to the ABC transporter superfamily	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD1_k127_2567078_18	1476973.JMMB01000007_gene2886	3.295e-200	626.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,25STR@186804|Peptostreptococcaceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD1_k127_2567078_6	1476973.JMMB01000007_gene2887	0.0	1019.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,25SQE@186804|Peptostreptococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD1_k127_2567078_32	37659.JNLN01000001_gene2170	8.32e-132	426.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36FGT@31979|Clostridiaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HKD1_k127_2567078_22	1476973.JMMB01000007_gene2889	7.236e-187	586.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25SBD@186804|Peptostreptococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HKD1_k127_2567078_42	272563.CD630_08520	8.957e-64	221.0	COG1846@1|root,COG1846@2|Bacteria,1VMGG@1239|Firmicutes,25CPS@186801|Clostridia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_2567078_44	1408823.AXUS01000028_gene1516	3.057e-56	198.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,25TSP@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
HKD1_k127_2567078_46	1301100.HG529447_gene4801	2.397e-47	171.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,36W78@31979|Clostridiaceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
HKD1_k127_2567278_19	1301100.HG529447_gene4801	7.399e-49	175.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,36W78@31979|Clostridiaceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
HKD1_k127_2567278_2	1476973.JMMB01000004_gene3398	7.719e-236	734.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,25QSM@186804|Peptostreptococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HKD1_k127_2567278_10	1476973.JMMB01000007_gene1514	2.414e-132	424.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,25QRA@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_2567278_13	1476973.JMMB01000007_gene1515	2.654e-104	340.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,25R92@186804|Peptostreptococcaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
HKD1_k127_2567278_20	1476973.JMMB01000007_gene1516	5.055e-31	122.0	COG4231@1|root,COG4231@2|Bacteria,1UHX9@1239|Firmicutes,24UZM@186801|Clostridia,25UC4@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
HKD1_k127_2567278_3	1476973.JMMB01000007_gene1517	2.051e-221	689.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,25STM@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
HKD1_k127_2567278_11	1511.CLOST_1472	4.859e-132	425.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia	186801|Clostridia	C	oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HKD1_k127_2567278_15	1476973.JMMB01000007_gene1519	2.482e-84	282.0	COG1014@1|root,COG1014@2|Bacteria,1V3RG@1239|Firmicutes,24I3Y@186801|Clostridia,25TGK@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
HKD1_k127_2567278_7	1476973.JMMB01000007_gene1520	3.671e-166	525.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,25QFH@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HKD1_k127_2567278_16	1391646.AVSU01000055_gene1124	2.366e-74	261.0	COG1275@1|root,COG1275@2|Bacteria,1UZAC@1239|Firmicutes,25DYX@186801|Clostridia	186801|Clostridia	P	Voltage-dependent anion channel	-	-	-	ko:K11041	ko05150,map05150	-	-	-	ko00000,ko00001,ko02042	2.A.16	-	-	SLAC1
HKD1_k127_2567278_5	1151292.QEW_2557	1.333e-191	604.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25QTJ@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HKD1_k127_2567278_8	1476973.JMMB01000007_gene1522	8.663e-164	522.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,25SX5@186804|Peptostreptococcaceae	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
HKD1_k127_2567278_4	1391646.AVSU01000108_gene2265	1.899e-194	626.0	COG0642@1|root,COG2984@1|root,COG2205@2|Bacteria,COG2984@2|Bacteria,1UXE3@1239|Firmicutes,25KZM@186801|Clostridia,25T3I@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_2567278_12	1476973.JMMB01000007_gene1523	3.79e-116	376.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,24FY2@186801|Clostridia,25SV6@186804|Peptostreptococcaceae	186801|Clostridia	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HKD1_k127_2567278_18	1476973.JMMB01000007_gene1524	2.807e-58	204.0	2BE6H@1|root,327XE@2|Bacteria,1UTUH@1239|Firmicutes,254DJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2567278_14	1476973.JMMB01000007_gene1525	2.968e-100	329.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,25RIA@186804|Peptostreptococcaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
HKD1_k127_2567278_9	1476973.JMMB01000007_gene1526	2.851e-153	486.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,25RDU@186804|Peptostreptococcaceae	186801|Clostridia	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
HKD1_k127_2567278_0	1476973.JMMB01000007_gene1527	0.0	1009.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25S1D@186804|Peptostreptococcaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HKD1_k127_2567278_1	1476973.JMMB01000007_gene1528	2.233e-271	839.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25R50@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
HKD1_k127_2567278_6	1476973.JMMB01000007_gene1530	1.015e-170	544.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25QYI@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
HKD1_k127_2567278_17	1476973.JMMB01000007_gene1531	3.443e-59	206.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25RQN@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
HKD1_k127_2567278_22	1304284.L21TH_1670	0.0001689	46.0	2ESIT@1|root,33K3H@2|Bacteria,1VNX8@1239|Firmicutes,24V0F@186801|Clostridia,36TAX@31979|Clostridiaceae	186801|Clostridia	S	PFAM small acid-soluble spore protein alpha beta type	-	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HKD1_k127_2567278_21	203119.Cthe_3195	9.587e-07	55.0	2EMBR@1|root,33F0Q@2|Bacteria,1VPIQ@1239|Firmicutes,24X7J@186801|Clostridia,3WQ7D@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2980321_2	1476973.JMMB01000004_gene3418	2.363e-137	438.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,25SWU@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_2980321_0	1391646.AVSU01000166_gene809	1.599e-171	544.0	COG5527@1|root,COG5527@2|Bacteria,1V1XJ@1239|Firmicutes,24PSJ@186801|Clostridia	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
HKD1_k127_2980321_16	1450694.BTS2_3455	0.0004241	52.0	COG1653@1|root,COG1653@2|Bacteria,1U1PF@1239|Firmicutes,4HF4G@91061|Bacilli,1ZQ36@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HKD1_k127_2980321_11	1476973.JMMB01000007_gene2209	8.55e-13	72.0	2C99Q@1|root,302JK@2|Bacteria,1UUHH@1239|Firmicutes,256SJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2980321_5	1292035.H476_3609	1.744e-54	196.0	COG1476@1|root,COG1476@2|Bacteria,1UPFA@1239|Firmicutes,25HFB@186801|Clostridia	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	immR_1	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_2980321_6	236814.IX39_04450	3.136e-49	189.0	COG1835@1|root,COG1835@2|Bacteria,4NWCJ@976|Bacteroidetes,1I9PV@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HKD1_k127_2980321_4	1301100.HG529246_gene2367	2.77e-112	366.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,248PN@186801|Clostridia,36DR9@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_2980321_1	1301100.HG529246_gene2368	4.342e-157	499.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,36DFE@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_2980321_8	1449050.JNLE01000003_gene2929	2.978e-38	153.0	COG1277@1|root,COG1277@2|Bacteria,1V9WP@1239|Firmicutes,24GT0@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
HKD1_k127_2980321_3	1301100.HG529246_gene2370	1.2e-127	414.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,25E8V@186801|Clostridia,36WAA@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_2980321_9	1476973.JMMB01000007_gene2432	9.694e-38	143.0	COG2002@1|root,COG2002@2|Bacteria,1UEYD@1239|Firmicutes,25JY4@186801|Clostridia,25TVV@186804|Peptostreptococcaceae	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2980321_7	1211817.CCAT010000041_gene3697	5.034e-40	164.0	COG0639@1|root,COG0639@2|Bacteria,1U60B@1239|Firmicutes,24EI8@186801|Clostridia,36JBA@31979|Clostridiaceae	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD1_k127_2980321_15	1526927.Plano_1013	6.133e-07	61.0	2DQX1@1|root,3394V@2|Bacteria,1VK3Q@1239|Firmicutes,4HXM1@91061|Bacilli,26HJ9@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2980321_14	1476973.JMMB01000005_gene3459	3.583e-07	51.0	COG2522@1|root,COG2522@2|Bacteria,1V00D@1239|Firmicutes,24H1A@186801|Clostridia,25SJT@186804|Peptostreptococcaceae	186801|Clostridia	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_2980321_12	1476973.JMMB01000005_gene3461	8.715e-12	65.0	2CDN8@1|root,2ZWE6@2|Bacteria,1W569@1239|Firmicutes,24VW0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_7	929704.Myrod_3501	6.927e-76	270.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,4NVQN@976|Bacteroidetes,1IA90@117743|Flavobacteriia	976|Bacteroidetes	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC
HKD1_k127_3023698_11	1301100.HG529241_gene7185	6.961e-49	176.0	28WAU@1|root,2ZIBA@2|Bacteria,1VMI2@1239|Firmicutes,24JTC@186801|Clostridia,36K7Z@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_18	1414720.CBYM010000010_gene3189	8.822e-10	64.0	2C0AX@1|root,33EUC@2|Bacteria,1VPIP@1239|Firmicutes,24P78@186801|Clostridia,36KQG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_12	457396.CSBG_03245	8.543e-38	143.0	COG0827@1|root,COG0827@2|Bacteria,1VKXJ@1239|Firmicutes,24NMI@186801|Clostridia,36MIG@31979|Clostridiaceae	186801|Clostridia	L	Staphylococcal protein of unknown function (DUF960)	-	-	-	-	-	-	-	-	-	-	-	-	DUF960
HKD1_k127_3023698_10	457396.CSBG_03246	1.799e-55	195.0	296CT@1|root,2ZTNK@2|Bacteria,1W1T4@1239|Firmicutes,24KXB@186801|Clostridia,36KA6@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_20	457396.CSBG_00700	4.024e-07	52.0	2BJ6S@1|root,32DG5@2|Bacteria,1UUIX@1239|Firmicutes,256WH@186801|Clostridia,36U48@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_1	318464.IO99_15075	2.075e-309	969.0	COG1241@1|root,COG3378@1|root,COG1241@2|Bacteria,COG3378@2|Bacteria,1VC38@1239|Firmicutes,25F2C@186801|Clostridia	186801|Clostridia	L	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_4	1120998.AUFC01000044_gene991	9.672e-167	539.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_3023698_15	1121342.AUCO01000012_gene1658	3.048e-28	130.0	2E2Y6@1|root,32XZ0@2|Bacteria,1VCZX@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3023698_21	318464.IO99_14920	0.0009763	52.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,36I0Z@31979|Clostridiaceae	186801|Clostridia	U	PFAM SEC-C motif	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
HKD1_k127_3023698_6	1292035.H476_3009	8.132e-81	270.0	COG3279@1|root,COG3279@2|Bacteria,1VG3R@1239|Firmicutes,24JN9@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HKD1_k127_3023698_19	1194526.A284_10020	1.291e-09	61.0	COG5562@1|root,COG5562@2|Bacteria,1VMIW@1239|Firmicutes,4HSJW@91061|Bacilli,4GZGP@90964|Staphylococcaceae	91061|Bacilli	S	Protein of unknown function (DUF1398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
HKD1_k127_3023698_17	1120951.AUBG01000002_gene1307	2.253e-14	74.0	COG5562@1|root,COG5562@2|Bacteria,4NR3A@976|Bacteroidetes,1I3BI@117743|Flavobacteriia	976|Bacteroidetes	S	Phage envelope protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
HKD1_k127_3023698_5	1391646.AVSU01000037_gene2027	6.057e-160	507.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia	186801|Clostridia	L	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD1_k127_3023698_0	1476973.JMMB01000007_gene2935	0.0	1027.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25T6X@186804|Peptostreptococcaceae	186801|Clostridia	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
HKD1_k127_3023698_9	1391646.AVSU01000044_gene1456	1.546e-62	218.0	COG0454@1|root,COG0456@2|Bacteria,1VBFC@1239|Firmicutes,24KAJ@186801|Clostridia,25TG9@186804|Peptostreptococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	bltD	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HKD1_k127_3023698_2	1391646.AVSU01000042_gene1408	1.583e-258	802.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25SX0@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HKD1_k127_3023698_3	1391646.AVSU01000042_gene1409	6.517e-230	714.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,25SUF@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_3054339_5	1151292.QEW_2804	5.901e-129	415.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25QQN@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD1_k127_3054339_1	1476973.JMMB01000007_gene2487	1.941e-251	781.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25QHF@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
HKD1_k127_3054339_6	1476973.JMMB01000007_gene2486	5.098e-114	375.0	2EZ4B@1|root,33SAI@2|Bacteria,1VRSY@1239|Firmicutes,24Z9Y@186801|Clostridia,25T7S@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3054339_4	1476973.JMMB01000007_gene2485	1.775e-145	469.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25RN1@186804|Peptostreptococcaceae	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
HKD1_k127_3054339_2	1476973.JMMB01000007_gene2484	1.437e-196	625.0	2F0AJ@1|root,33TDU@2|Bacteria,1VSCP@1239|Firmicutes,24XHH@186801|Clostridia,25R8X@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3054339_8	1301100.HG529354_gene4341	1.082e-28	116.0	28XIX@1|root,2ZJG5@2|Bacteria,1W5N3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3054339_0	1476973.JMMB01000007_gene2482	5.931e-260	803.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25T2N@186804|Peptostreptococcaceae	186801|Clostridia	E	Lysine-2,3-aminomutase	kamA	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0016869,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051536,GO:0051540,GO:0070279,GO:0097159,GO:1901363	5.4.3.9	ko:K19814	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
HKD1_k127_3054339_7	1476973.JMMB01000007_gene2481	2.374e-49	178.0	29UDK@1|root,3404Y@2|Bacteria,1VXKV@1239|Firmicutes,251WK@186801|Clostridia,25U49@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3054339_3	1476973.JMMB01000007_gene2480	2.461e-179	567.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25SBV@186804|Peptostreptococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_3054339_9	445973.CLOBAR_02620	8.631e-21	93.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25QF5@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_3054843_12	195103.CPF_0520	7.89e-65	228.0	COG0569@1|root,COG0569@2|Bacteria,1V80K@1239|Firmicutes,24PKP@186801|Clostridia,36ENU@31979|Clostridiaceae	186801|Clostridia	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
HKD1_k127_3054843_15	574375.BAGA_01630	1.563e-41	155.0	COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,1ZHV2@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	padR	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HKD1_k127_3054843_17	1292035.H476_0798	4.258e-33	138.0	COG4858@1|root,COG4858@2|Bacteria,1TUPD@1239|Firmicutes,25JWK@186801|Clostridia,25TPM@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3054843_4	1476973.JMMB01000007_gene1561	1.057e-165	527.0	COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,24BZZ@186801|Clostridia,25T9D@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
HKD1_k127_3054843_13	1292035.H476_2464	2.109e-49	180.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,25RXB@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HKD1_k127_3054843_1	1476973.JMMB01000007_gene1855	2.584e-318	984.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,25QKV@186804|Peptostreptococcaceae	186801|Clostridia	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD1_k127_3054843_14	1476973.JMMB01000007_gene1721	4.219e-48	174.0	2E6A2@1|root,3182Z@2|Bacteria,1V931@1239|Firmicutes,25JW0@186801|Clostridia,25TMK@186804|Peptostreptococcaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HKD1_k127_3054843_19	1321778.HMPREF1982_00806	6.093e-06	48.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
HKD1_k127_3054843_18	1122216.AUHW01000019_gene54	3.973e-21	95.0	COG0640@1|root,COG0640@2|Bacteria,1V9XT@1239|Firmicutes,4H8ZZ@909932|Negativicutes	909932|Negativicutes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HKD1_k127_3054843_3	1476973.JMMB01000007_gene2299	2.196e-168	532.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,25SEZ@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_3054843_2	1476973.JMMB01000007_gene2298	2.131e-262	812.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25SBQ@186804|Peptostreptococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	mepA2	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_3054843_0	1476973.JMMB01000007_gene1545	0.0	1132.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
HKD1_k127_3054843_7	1391646.AVSU01000049_gene1616	4.634e-134	437.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,25RRG@186804|Peptostreptococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
HKD1_k127_3054843_11	1476973.JMMB01000007_gene1608	3.119e-68	237.0	COG4720@1|root,COG4720@2|Bacteria,1TTCZ@1239|Firmicutes,25MT7@186801|Clostridia,25TDE@186804|Peptostreptococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HKD1_k127_3054843_8	1476973.JMMB01000007_gene1850	1.016e-123	399.0	28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,24A9T@186801|Clostridia,25T39@186804|Peptostreptococcaceae	186801|Clostridia	S	EcsC protein family	ecsC	-	-	-	-	-	-	-	-	-	-	-	EcsC
HKD1_k127_3054843_10	272563.CD630_15160	1.373e-82	284.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
HKD1_k127_3054843_5	272563.CD630_15060	1.165e-165	532.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25SUZ@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_3054843_6	1301100.HG529330_gene4612	1.087e-138	443.0	COG0500@1|root,COG2226@2|Bacteria,1TR3E@1239|Firmicutes,249HI@186801|Clostridia,36GB1@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD1_k127_3054843_9	1476973.JMMB01000007_gene2463	8.644e-105	342.0	COG1595@1|root,COG1595@2|Bacteria,1V9TA@1239|Firmicutes,24IU4@186801|Clostridia,25S75@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_339678_63	272563.CD630_09180	9.072e-18	93.0	COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,24IDX@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD1_k127_339678_50	1462526.BN990_03905	1.276e-50	190.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,4HMRU@91061|Bacilli	91061|Bacilli	L	N-terminal phage replisome organiser (Phage_rep_org_N)	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2,Phage_rep_org_N
HKD1_k127_339678_40	1294142.CINTURNW_1011	3.115e-93	312.0	COG1235@1|root,COG1235@2|Bacteria,1TSJF@1239|Firmicutes,249ZR@186801|Clostridia,36HFM@31979|Clostridiaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HKD1_k127_339678_28	1408823.AXUS01000024_gene2694	2.777e-124	404.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia	186801|Clostridia	L	RecT family	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
HKD1_k127_339678_56	1408823.AXUS01000024_gene2693	1.946e-35	155.0	COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,248AP@186801|Clostridia	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23,AAA_27,AAA_29
HKD1_k127_339678_21	1408823.AXUS01000024_gene2692	1.759e-153	507.0	COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,248AP@186801|Clostridia	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23,AAA_27,AAA_29,DUF2813
HKD1_k127_339678_46	1444310.JANV01000162_gene1209	1.301e-58	214.0	COG3561@1|root,COG3561@2|Bacteria,1UP8V@1239|Firmicutes	1239|Firmicutes	K	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
HKD1_k127_339678_68	1443125.Z962_p0008	1.331e-07	55.0	COG1476@1|root,COG1476@2|Bacteria,1UGHC@1239|Firmicutes,25NZB@186801|Clostridia,36NZP@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_339678_52	926561.KB900623_gene728	2.037e-46	175.0	COG1974@1|root,COG1974@2|Bacteria,1UVB3@1239|Firmicutes,25KFP@186801|Clostridia,3WC1H@53433|Halanaerobiales	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
HKD1_k127_339678_23	272563.CD630_25190	1.261e-141	458.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,25QY8@186804|Peptostreptococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HKD1_k127_339678_19	1476973.JMMB01000007_gene1505	3.979e-170	537.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,25QXB@186804|Peptostreptococcaceae	186801|Clostridia	I	Diacylglycerol kinase catalytic domain (presumed)	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HKD1_k127_339678_37	1476973.JMMB01000007_gene1504	3.01e-113	368.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,25SZB@186804|Peptostreptococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
HKD1_k127_339678_29	1476973.JMMB01000007_gene1503	5.863e-123	397.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,25QGU@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HKD1_k127_339678_3	1476973.JMMB01000007_gene1502	0.0	1018.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,25QDM@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_339678_30	1292035.H476_0775	1.313e-121	396.0	COG0407@1|root,COG0407@2|Bacteria,1TSUR@1239|Firmicutes,24ARM@186801|Clostridia,25SS7@186804|Peptostreptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
HKD1_k127_339678_36	1292035.H476_0776	7.699e-114	374.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25RJ1@186804|Peptostreptococcaceae	186801|Clostridia	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HKD1_k127_339678_5	1476973.JMMB01000007_gene1432	3.348e-294	912.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,25R30@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HKD1_k127_339678_15	1476973.JMMB01000007_gene1431	1.212e-182	574.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,25STP@186804|Peptostreptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246	ko:K14080	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R09098,R10000	RC00035,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD1_k127_339678_35	1391646.AVSU01000049_gene1624	1.5e-116	377.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25SDM@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	mtbC	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
HKD1_k127_339678_13	1391646.AVSU01000049_gene1625	1.302e-212	662.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,248G3@186801|Clostridia,25SEQ@186804|Peptostreptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HKD1_k127_339678_33	1476973.JMMB01000007_gene1501	3.651e-118	384.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,25T5C@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF348)	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
HKD1_k127_339678_41	1121090.KB894715_gene2722	2.234e-81	307.0	COG1216@1|root,COG4641@1|root,COG1216@2|Bacteria,COG4641@2|Bacteria,1TP05@1239|Firmicutes,4HEG5@91061|Bacilli,1ZRJG@1386|Bacillus	91061|Bacilli	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_2
HKD1_k127_339678_66	1288.SXYLSMQ121_1012	1.318e-11	79.0	COG0463@1|root,COG0463@2|Bacteria,1UUTG@1239|Firmicutes,4HTQQ@91061|Bacilli,4GZ8X@90964|Staphylococcaceae	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_339678_44	1227360.C176_05747	5.062e-72	277.0	COG1216@1|root,COG4641@1|root,COG1216@2|Bacteria,COG4641@2|Bacteria,1TP05@1239|Firmicutes,4HEG5@91061|Bacilli	91061|Bacilli	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_2
HKD1_k127_339678_57	1220589.CD32_06430	1.988e-35	158.0	COG1506@1|root,COG1506@2|Bacteria,1VRIY@1239|Firmicutes,4HTEG@91061|Bacilli	91061|Bacilli	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_339678_22	457396.CSBG_00391	2.272e-143	472.0	COG4641@1|root,COG4641@2|Bacteria,1TQDC@1239|Firmicutes,24C5S@186801|Clostridia,36F27@31979|Clostridiaceae	186801|Clostridia	M	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_1
HKD1_k127_339678_20	1347392.CCEZ01000075_gene3178	2.126e-165	529.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,36FEX@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD1_k127_339678_39	1476973.JMMB01000007_gene1496	1.004e-100	348.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,24K2H@186801|Clostridia,25TYN@186804|Peptostreptococcaceae	186801|Clostridia	E	Leucine Rich repeats (2 copies)	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CW_binding_2,DUF3888,GA-like,LRR_4,LRR_6,LRR_8
HKD1_k127_339678_43	1476973.JMMB01000007_gene1495	2.042e-73	254.0	COG1215@1|root,COG1215@2|Bacteria,1V7YV@1239|Firmicutes,24IIA@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_339678_34	573061.Clocel_2494	3.712e-117	406.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
HKD1_k127_339678_64	545697.HMPREF0216_01400	4.696e-16	86.0	2EFIV@1|root,339B9@2|Bacteria,1VIU3@1239|Firmicutes,24RWF@186801|Clostridia,36MVZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_339678_32	1476973.JMMB01000007_gene1618	6.755e-120	387.0	2F1M8@1|root,33UMK@2|Bacteria,1VV9D@1239|Firmicutes,24C5I@186801|Clostridia,25SSF@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_339678_6	1476973.JMMB01000007_gene1616	1.162e-285	880.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25T4E@186804|Peptostreptococcaceae	186801|Clostridia	JKL	DbpA RNA binding domain	dbpA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD1_k127_339678_9	1476973.JMMB01000007_gene1578	1.405e-250	780.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,25QTM@186804|Peptostreptococcaceae	186801|Clostridia	P	Substrate binding domain of ABC-type glycine betaine transport system	opuCC	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
HKD1_k127_339678_16	195103.CPF_0537	7.779e-182	574.0	COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,248YZ@186801|Clostridia,36EGJ@31979|Clostridiaceae	186801|Clostridia	E	glycine, betaine	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
HKD1_k127_339678_60	1301100.HG529275_gene1562	6.402e-26	109.0	2E3YH@1|root,32YVH@2|Bacteria,1UJDZ@1239|Firmicutes,25F2E@186801|Clostridia,36MNZ@31979|Clostridiaceae	186801|Clostridia	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
HKD1_k127_339678_38	1121324.CLIT_10c03990	3.212e-106	353.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,25TGR@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_339678_17	1476973.JMMB01000007_gene1614	8.024e-182	572.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,25QGA@186804|Peptostreptococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD1_k127_339678_67	1395587.P364_0131595	3.135e-08	55.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,26U7N@186822|Paenibacillaceae	91061|Bacilli	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
HKD1_k127_339678_18	1292035.H476_2972	1.259e-172	544.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia,25T3E@186804|Peptostreptococcaceae	186801|Clostridia	T	Two component signalling adaptor domain	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
HKD1_k127_339678_47	1391646.AVSU01000047_gene1603	2.499e-56	198.0	COG0599@1|root,COG0599@2|Bacteria,1V8W7@1239|Firmicutes,24K0P@186801|Clostridia,25TSR@186804|Peptostreptococcaceae	186801|Clostridia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
HKD1_k127_339678_53	1487921.DP68_01110	3.442e-45	167.0	COG1846@1|root,COG1846@2|Bacteria,1VB8I@1239|Firmicutes,24KAQ@186801|Clostridia,36J3H@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_339678_11	1476973.JMMB01000007_gene1613	6.285e-243	754.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25R1F@186804|Peptostreptococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD1_k127_339678_0	1476973.JMMB01000007_gene1612	0.0	1246.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25QFA@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhA1	-	1.17.1.5	ko:K20447	ko00760,ko01120,map00760,map01120	-	R01720	RC00589	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HKD1_k127_339678_42	1476973.JMMB01000007_gene1611	4.843e-79	265.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,25UH8@186804|Peptostreptococcaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
HKD1_k127_339678_31	1476973.JMMB01000007_gene1610	6.588e-120	391.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,25UH9@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.5	ko:K20445	ko00760,ko01120,map00760,map01120	-	R01720	RC00589	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HKD1_k127_339678_2	1476973.JMMB01000007_gene1890	0.0	1029.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,25SK8@186804|Peptostreptococcaceae	186801|Clostridia	J	Class II release factor RF3, C-terminal domain	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HKD1_k127_339678_25	931276.Cspa_c15980	4.912e-133	428.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,25CBN@186801|Clostridia,36WSY@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HKD1_k127_339678_10	1476973.JMMB01000007_gene1609	1.64e-244	759.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,25STF@186804|Peptostreptococcaceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD1_k127_339678_45	1301100.HG529417_gene2991	1.825e-64	228.0	COG5581@1|root,COG5581@2|Bacteria,1UFPY@1239|Firmicutes,24ICK@186801|Clostridia,36IT8@31979|Clostridiaceae	186801|Clostridia	M	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
HKD1_k127_339678_1	1476973.JMMB01000007_gene1607	0.0	1114.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,25SFD@186804|Peptostreptococcaceae	186801|Clostridia	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD1_k127_339678_58	293826.Amet_4575	4.788e-29	118.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,36N12@31979|Clostridiaceae	186801|Clostridia	CQ	Ethanolamine utilization protein EutN carboxysome structural protein Ccml	ccmL	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
HKD1_k127_339678_59	1476973.JMMB01000007_gene1605	9.205e-28	117.0	29UPQ@1|root,30G1E@2|Bacteria,1UF10@1239|Firmicutes,25K1I@186801|Clostridia,25U5B@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_339678_51	1391646.AVSU01000038_gene1994	2.18e-47	170.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25TUC@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD1_k127_339678_54	1476973.JMMB01000007_gene1603	3.917e-45	166.0	COG4577@1|root,COG4577@2|Bacteria,1VBMF@1239|Firmicutes,24P13@186801|Clostridia,25TVM@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD1_k127_339678_55	1476973.JMMB01000007_gene1601	5.298e-38	143.0	COG4577@1|root,COG4577@2|Bacteria,1UGFD@1239|Firmicutes,25JCX@186801|Clostridia,25TN0@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD1_k127_339678_7	1476973.JMMB01000007_gene1600	3.776e-267	825.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,25RRQ@186804|Peptostreptococcaceae	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
HKD1_k127_339678_49	1449355.JQNR01000003_gene813	8.196e-52	190.0	COG0043@1|root,COG0163@1|root,COG0043@2|Bacteria,COG0163@2|Bacteria,2GKID@201174|Actinobacteria	201174|Actinobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HKD1_k127_339678_27	1476973.JMMB01000007_gene1598	2.871e-126	404.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24A9U@186801|Clostridia,25S9B@186804|Peptostreptococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD1_k127_339678_4	1476973.JMMB01000007_gene1597	0.0	997.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,25SW3@186804|Peptostreptococcaceae	186801|Clostridia	F	Amidohydrolase family	allB	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HKD1_k127_339678_14	1476973.JMMB01000007_gene1596	3.093e-183	575.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,25S9U@186804|Peptostreptococcaceae	186801|Clostridia	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
HKD1_k127_339678_24	1476973.JMMB01000007_gene1595	1.162e-138	442.0	COG1878@1|root,COG1878@2|Bacteria,1UZ93@1239|Firmicutes,25CZD@186801|Clostridia,25S71@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HKD1_k127_339678_12	1476973.JMMB01000007_gene1594	2.407e-226	707.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25QQE@186804|Peptostreptococcaceae	186801|Clostridia	F	Permease family	pbuX	-	-	ko:K03458,ko:K16345	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.4.2	-	-	Xan_ur_permease
HKD1_k127_339678_61	1476973.JMMB01000007_gene2050	3.334e-22	105.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,24IBK@186801|Clostridia,25TGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD1_k127_339678_8	1476973.JMMB01000007_gene1585	9.278e-261	807.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,25QPW@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HKD1_k127_339678_26	1476973.JMMB01000007_gene1584	1.573e-127	409.0	COG1357@1|root,COG1357@2|Bacteria,1V2UP@1239|Firmicutes,24G5Y@186801|Clostridia,25S24@186804|Peptostreptococcaceae	186801|Clostridia	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
HKD1_k127_347832_48	457396.CSBG_00444	5.104e-58	211.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,36UU1@31979|Clostridiaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_347832_63	1236514.BAKL01000008_gene1005	3.68e-08	65.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	1.1.1.34,2.7.1.89	ko:K00021,ko:K07251	ko00730,ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00730,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082,R02134	RC00002,RC00004,RC00017,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Choline_kinase
HKD1_k127_347832_61	118173.KB235914_gene3855	2.628e-10	73.0	COG2133@1|root,COG2931@1|root,COG5434@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG5434@2|Bacteria,1G0JG@1117|Cyanobacteria,1HADF@1150|Oscillatoriales	1117|Cyanobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349,DUF4347,Pectate_lyase_3
HKD1_k127_347832_40	331678.Cphamn1_2146	6.165e-84	286.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lsgF	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_347832_46	1196031.ALEG01000028_gene4374	9.535e-62	227.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_347832_62	483216.BACEGG_02784	1.498e-08	66.0	2BT9H@1|root,32NEX@2|Bacteria,4NR9H@976|Bacteroidetes,2FT7T@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
HKD1_k127_347832_55	1121324.CLIT_14c01280	5.431e-31	138.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25SG4@186804|Peptostreptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
HKD1_k127_347832_58	1391646.AVSU01000050_gene1665	1.324e-23	115.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia	186801|Clostridia	M	chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HKD1_k127_347832_32	1476973.JMMB01000007_gene1270	1.978e-127	411.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia,25QVC@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HKD1_k127_347832_24	1476973.JMMB01000007_gene1269	1.138e-140	449.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,25QIG@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD1_k127_347832_57	1301100.HG529275_gene1639	4.478e-24	102.0	2999Z@1|root,2ZWD5@2|Bacteria,1W6JV@1239|Firmicutes,256N2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_347832_34	1476973.JMMB01000007_gene1267	1.488e-99	326.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,25QI8@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HKD1_k127_347832_27	1476973.JMMB01000007_gene1266	4.351e-139	444.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,25R1E@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD1_k127_347832_16	1476973.JMMB01000007_gene1265	2.234e-165	523.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,25R59@186804|Peptostreptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HKD1_k127_347832_22	1476973.JMMB01000007_gene1264	5.227e-142	452.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25QY9@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HKD1_k127_347832_7	1476973.JMMB01000007_gene1263	1.32e-221	691.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,25QYM@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD1_k127_347832_9	1476973.JMMB01000007_gene1262	5.527e-218	678.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25QQW@186804|Peptostreptococcaceae	186801|Clostridia	JKL	helicase superfamily c-terminal domain	cshA2	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
HKD1_k127_347832_36	1476973.JMMB01000007_gene1261	2.479e-89	298.0	COG3103@1|root,COG3584@1|root,COG3103@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,2493P@186801|Clostridia,25T9G@186804|Peptostreptococcaceae	186801|Clostridia	T	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3
HKD1_k127_347832_11	1415775.U729_317	3.828e-185	594.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,36HEA@31979|Clostridiaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Big_2,CW_binding_2,Cu_amine_oxidN1,SH3_3
HKD1_k127_347832_26	1301100.HG529275_gene1561	4.151e-140	450.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,36DBX@31979|Clostridiaceae	186801|Clostridia	G	PFAM periplasmic binding protein	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HKD1_k127_347832_21	1301100.HG529275_gene1560	6.223e-151	482.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HKD1_k127_347832_2	1301100.HG529275_gene1559	4.852e-267	827.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
HKD1_k127_347832_44	1476973.JMMB01000007_gene1257	3e-68	233.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,25RRD@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
HKD1_k127_347832_19	1476973.JMMB01000007_gene1256	1.038e-152	487.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,25RF7@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD1_k127_347832_1	1476973.JMMB01000007_gene1255	3.471e-271	846.0	COG2199@1|root,COG2199@2|Bacteria,1UJ72@1239|Firmicutes,25EXG@186801|Clostridia,25TMH@186804|Peptostreptococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
HKD1_k127_347832_4	1476973.JMMB01000007_gene1254	1.057e-258	810.0	COG2199@1|root,COG3706@2|Bacteria,1V6MC@1239|Firmicutes,24JED@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3,TPR_12
HKD1_k127_347832_20	1476973.JMMB01000007_gene1253	5.437e-151	482.0	COG0515@1|root,COG0515@2|Bacteria,1VTMK@1239|Firmicutes,24YYX@186801|Clostridia,25R9K@186804|Peptostreptococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HKD1_k127_347832_42	318464.IO99_12005	1.059e-77	267.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,36HCH@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_347832_52	1301100.HG529356_gene2081	1.74e-42	157.0	2DPF4@1|root,32UKX@2|Bacteria,1VG33@1239|Firmicutes,24RXQ@186801|Clostridia,36N3R@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3892
HKD1_k127_347832_31	1476973.JMMB01000007_gene1251	3.689e-128	421.0	2DYZD@1|root,32V6B@2|Bacteria,1W15X@1239|Firmicutes,24Z12@186801|Clostridia,25T8I@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_347832_33	272563.CD630_17500	2.837e-127	410.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,25SSJ@186804|Peptostreptococcaceae	186801|Clostridia	I	FGGY family of carbohydrate kinases, C-terminal domain	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD1_k127_347832_6	1476973.JMMB01000007_gene1249	2.838e-227	707.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,25SUG@186804|Peptostreptococcaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HKD1_k127_347832_35	1476973.JMMB01000007_gene1248	3.141e-95	320.0	COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,25EUD@186801|Clostridia,25SZP@186804|Peptostreptococcaceae	186801|Clostridia	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
HKD1_k127_347832_38	1476973.JMMB01000007_gene1245	1.969e-84	282.0	COG0526@1|root,COG0526@2|Bacteria,1UFQB@1239|Firmicutes,24IHR@186801|Clostridia,25TCH@186804|Peptostreptococcaceae	186801|Clostridia	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
HKD1_k127_347832_18	1301100.HG529345_gene3157	3.863e-157	505.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,36E8K@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the sodium-dependent transport of glutamate	gltC	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
HKD1_k127_347832_8	1476973.JMMB01000007_gene1243	7.262e-219	685.0	COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,2486W@186801|Clostridia,25SN4@186804|Peptostreptococcaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD1_k127_347832_60	536232.CLM_0751	1.993e-18	90.0	COG1846@1|root,COG1846@2|Bacteria,1VEFZ@1239|Firmicutes,24MSB@186801|Clostridia,36IX7@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_347832_54	1211817.CCAT010000043_gene3559	3.074e-31	126.0	COG3543@1|root,COG3543@2|Bacteria,1VFVM@1239|Firmicutes,24R1N@186801|Clostridia,36KX0@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
HKD1_k127_347832_41	1476973.JMMB01000007_gene1239	3.679e-80	271.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,25RJF@186804|Peptostreptococcaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HKD1_k127_347832_15	1476973.JMMB01000007_gene1238	3.388e-168	537.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,25SRB@186804|Peptostreptococcaceae	186801|Clostridia	M	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
HKD1_k127_347832_3	1301100.HG529346_gene4280	3.521e-262	816.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,36DCM@31979|Clostridiaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HKD1_k127_347832_53	1301100.HG529346_gene4281	1.417e-41	154.0	2FCSH@1|root,344VI@2|Bacteria,1W1BR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_347832_43	272563.CD630_17150	9.949e-75	252.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia	186801|Clostridia	H	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
HKD1_k127_347832_37	1408823.AXUS01000001_gene713	7.712e-85	282.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,25S8B@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
HKD1_k127_347832_10	1476973.JMMB01000007_gene1235	8.392e-191	597.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,25REP@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HKD1_k127_347832_39	1301100.HG529346_gene4285	5.314e-84	281.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,36J7G@31979|Clostridiaceae	186801|Clostridia	H	molybdenum cofactor	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
HKD1_k127_347832_25	1476973.JMMB01000007_gene1234	2.877e-140	449.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,25RYR@186804|Peptostreptococcaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HKD1_k127_347832_28	1476973.JMMB01000007_gene1233	4.608e-137	439.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,25QWS@186804|Peptostreptococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
HKD1_k127_347832_49	1301100.HG529346_gene4288	3.476e-52	185.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,36JJG@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HKD1_k127_347832_14	1476973.JMMB01000007_gene2182	1.39e-180	567.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia,25QEI@186804|Peptostreptococcaceae	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
HKD1_k127_347832_45	272563.CD630_17060	1.162e-65	230.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,25TDY@186804|Peptostreptococcaceae	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
HKD1_k127_347832_12	272563.CD630_17050	4.613e-184	580.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25SMY@186804|Peptostreptococcaceae	186801|Clostridia	C	biosynthesis protein ThiH	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HKD1_k127_347832_23	1301100.HG529346_gene4293	4.1e-141	451.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,36G8Q@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HKD1_k127_347832_30	1301100.HG529346_gene4294	1.036e-130	421.0	COG0476@1|root,COG0476@2|Bacteria,1UYFC@1239|Firmicutes,247UZ@186801|Clostridia,36F4H@31979|Clostridiaceae	186801|Clostridia	H	Thiamine biosynthesis protein ThiF	thiF	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS-like
HKD1_k127_347832_59	1301100.HG529346_gene4295	6.473e-19	88.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes	1239|Firmicutes	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HKD1_k127_347832_17	1211817.CCAT010000083_gene1552	3.79e-163	526.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,36DVM@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_347832_51	1033737.CAEV01000007_gene2565	8.727e-47	169.0	2C8U7@1|root,32RMX@2|Bacteria,1VB3M@1239|Firmicutes,24R2W@186801|Clostridia,36KYE@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_347832_47	1476973.JMMB01000007_gene1960	4.952e-59	206.0	2DM4G@1|root,31PFJ@2|Bacteria,1V7ZT@1239|Firmicutes,24J8U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_347832_5	420246.GTNG_3422	7.13e-247	780.0	COG0582@1|root,COG0582@2|Bacteria,1U0FV@1239|Firmicutes,4HBKR@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	tnpB	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HKD1_k127_347832_13	86416.Clopa_2265	1.219e-181	574.0	COG4974@1|root,COG4974@2|Bacteria,1UJMF@1239|Firmicutes,25EDE@186801|Clostridia,36HK7@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HKD1_k127_347832_29	1476973.JMMB01000007_gene1229	7.484e-135	434.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25SXS@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_347832_0	1476973.JMMB01000007_gene1227	0.0	1442.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25QXX@186804|Peptostreptococcaceae	186801|Clostridia	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HKD1_k127_363461_38	1476973.JMMB01000007_gene655	6.449e-120	387.0	COG1413@1|root,COG1413@2|Bacteria,1V61C@1239|Firmicutes,24FZ1@186801|Clostridia,25REB@186804|Peptostreptococcaceae	186801|Clostridia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,HTH_40
HKD1_k127_363461_12	1301100.HG529403_gene6783	1.44e-245	762.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,36DCE@31979|Clostridiaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HKD1_k127_363461_51	1476973.JMMB01000007_gene653	1.316e-49	177.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,25RSJ@186804|Peptostreptococcaceae	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
HKD1_k127_363461_41	1476973.JMMB01000007_gene652	1.136e-102	336.0	COG4478@1|root,COG4478@2|Bacteria,1VGZ1@1239|Firmicutes,25CJ1@186801|Clostridia,25UMJ@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
HKD1_k127_363461_8	1476973.JMMB01000007_gene651	2.92e-321	985.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25QZK@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter, ATP-binding protein	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HKD1_k127_363461_35	1476973.JMMB01000007_gene650	6.987e-131	419.0	arCOG08608@1|root,32CXY@2|Bacteria,1V6CC@1239|Firmicutes,24AQP@186801|Clostridia,25RFQ@186804|Peptostreptococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C (alpha toxin)	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Zn_dep_PLPC
HKD1_k127_363461_36	1476973.JMMB01000007_gene649	4.937e-128	413.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25R4H@186804|Peptostreptococcaceae	186801|Clostridia	M	Ami_3	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
HKD1_k127_363461_27	1476973.JMMB01000007_gene647	9.466e-158	503.0	COG0265@1|root,COG0265@2|Bacteria,1VU1H@1239|Firmicutes,2504R@186801|Clostridia,25QRY@186804|Peptostreptococcaceae	186801|Clostridia	O	SpoIVB peptidase S55	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
HKD1_k127_363461_39	1476973.JMMB01000007_gene646	1.823e-117	381.0	2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,24JQP@186801|Clostridia,25SWV@186804|Peptostreptococcaceae	186801|Clostridia	S	Sporulation protein YunB (Spo_YunB)	yunB	-	-	-	-	-	-	-	-	-	-	-	Spore_YunB
HKD1_k127_363461_2	1476973.JMMB01000007_gene645	0.0	1299.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,25QIB@186804|Peptostreptococcaceae	186801|Clostridia	M	penicillin-binding protein	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HKD1_k127_363461_48	1476973.JMMB01000007_gene644	8.849e-64	219.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,25RM5@186804|Peptostreptococcaceae	186801|Clostridia	S	SpoVAC/SpoVAEB sporulation membrane protein	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD1_k127_363461_15	1301100.HG529405_gene296	4.384e-210	654.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia,36DQK@31979|Clostridiaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HKD1_k127_363461_44	1476973.JMMB01000007_gene642	8.564e-79	264.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,25RDT@186804|Peptostreptococcaceae	186801|Clostridia	S	SpoVAC/SpoVAEB sporulation membrane protein	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HKD1_k127_363461_47	1476973.JMMB01000007_gene641	2.225e-66	228.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
HKD1_k127_363461_34	1476973.JMMB01000007_gene639	4.33e-143	456.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,25T00@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_363461_43	1301100.HG529405_gene301	6.442e-79	264.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,36ITI@31979|Clostridiaceae	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HKD1_k127_363461_49	1476973.JMMB01000007_gene637	9.908e-62	213.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,25TPZ@186804|Peptostreptococcaceae	186801|Clostridia	T	STAS domain	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HKD1_k127_363461_9	1301100.HG529405_gene303	6.582e-318	983.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,36E8E@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
HKD1_k127_363461_7	1476973.JMMB01000007_gene635	0.0	1003.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25QDG@186804|Peptostreptococcaceae	186801|Clostridia	JKL	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD1_k127_363461_31	1476973.JMMB01000007_gene634	5.68e-151	483.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25R5B@186804|Peptostreptococcaceae	186801|Clostridia	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HKD1_k127_363461_0	1476973.JMMB01000007_gene633	0.0	1462.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R2X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HKD1_k127_363461_33	1476973.JMMB01000007_gene632	2.694e-148	471.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25QR5@186804|Peptostreptococcaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD1_k127_363461_13	1476973.JMMB01000007_gene631	8.388e-234	725.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25QNU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HKD1_k127_363461_14	1476973.JMMB01000007_gene630	2.161e-222	692.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25R11@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD1_k127_363461_18	1301100.HG529407_gene226	9.108e-193	604.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HKD1_k127_363461_3	1476973.JMMB01000007_gene628	0.0	1219.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,25QTG@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD1_k127_363461_54	1391646.AVSU01000056_gene1289	0.0004604	43.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,25RYT@186804|Peptostreptococcaceae	186801|Clostridia	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
HKD1_k127_363461_28	1476973.JMMB01000007_gene899	1.736e-157	499.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25SRK@186804|Peptostreptococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD1_k127_363461_17	1301100.HG529230_gene5357	1.182e-194	610.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,36EB1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HKD1_k127_363461_20	1476973.JMMB01000007_gene897	1.019e-181	574.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ITQ@186801|Clostridia,25SE3@186804|Peptostreptococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HKD1_k127_363461_52	1301100.HG529230_gene5355	1.102e-39	149.0	2C0TZ@1|root,344AK@2|Bacteria,1W1F7@1239|Firmicutes,253M9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_363461_50	1476973.JMMB01000007_gene624	8.86e-54	190.0	arCOG02716@1|root,3300V@2|Bacteria,1VF7E@1239|Firmicutes,24T1W@186801|Clostridia,25RSH@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_363461_45	1476973.JMMB01000007_gene623	4.6e-74	250.0	2AIN5@1|root,3194H@2|Bacteria,1V6U3@1239|Firmicutes,24JK0@186801|Clostridia,25RGJ@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3842
HKD1_k127_363461_53	1476973.JMMB01000007_gene622	2.434e-33	129.0	COG1532@1|root,COG1532@2|Bacteria,1UEI0@1239|Firmicutes,25JFD@186801|Clostridia,25TW1@186804|Peptostreptococcaceae	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
HKD1_k127_363461_32	1476973.JMMB01000007_gene621	2.656e-149	475.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,25T6H@186804|Peptostreptococcaceae	186801|Clostridia	H	Biotin/lipoate A/B protein ligase family	lipM	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
HKD1_k127_363461_22	1476973.JMMB01000007_gene620	7.105e-174	548.0	COG2516@1|root,COG2516@2|Bacteria,1TQF6@1239|Firmicutes,24AAS@186801|Clostridia,25T1F@186804|Peptostreptococcaceae	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
HKD1_k127_363461_29	1476973.JMMB01000007_gene619	5.308e-156	495.0	COG1856@1|root,COG1856@2|Bacteria,1V23U@1239|Firmicutes,24E3M@186801|Clostridia,25T3G@186804|Peptostreptococcaceae	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_363461_5	1476973.JMMB01000007_gene618	0.0	1182.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,25QSJ@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HKD1_k127_363461_46	1476973.JMMB01000007_gene616	7.252e-68	231.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,25RKT@186804|Peptostreptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
HKD1_k127_363461_1	1476973.JMMB01000007_gene615	0.0	1356.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,25R23@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
HKD1_k127_363461_24	1476973.JMMB01000007_gene614	1.374e-168	531.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,25QC7@186804|Peptostreptococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD1_k127_363461_10	1476973.JMMB01000007_gene613	1.835e-283	872.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,25SZ7@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
HKD1_k127_363461_19	1476973.JMMB01000007_gene612	6.573e-188	589.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,25QTA@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
HKD1_k127_363461_30	1476973.JMMB01000007_gene611	1.554e-152	483.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,25SF1@186804|Peptostreptococcaceae	186801|Clostridia	D	AAA domain	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
HKD1_k127_363461_11	1301100.HG529407_gene244	1.203e-275	850.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,36EPX@31979|Clostridiaceae	186801|Clostridia	C	Dihydrolipoyl dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
HKD1_k127_363461_21	1476973.JMMB01000007_gene609	1.549e-177	558.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,25R45@186804|Peptostreptococcaceae	186801|Clostridia	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HKD1_k127_363461_37	1301100.HG529407_gene246	1.984e-126	406.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,36H5R@31979|Clostridiaceae	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
HKD1_k127_363461_23	1476973.JMMB01000007_gene607	1.2e-169	534.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,25QYE@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HKD1_k127_363461_40	1476973.JMMB01000007_gene606	2.242e-117	379.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,25RK8@186804|Peptostreptococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
HKD1_k127_363461_6	1476973.JMMB01000007_gene605	0.0	1027.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25QRD@186804|Peptostreptococcaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HKD1_k127_363461_26	1476973.JMMB01000007_gene604	4.905e-163	514.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,25QN6@186804|Peptostreptococcaceae	186801|Clostridia	D	Anion-transporting ATPase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
HKD1_k127_363461_4	1476973.JMMB01000007_gene603	0.0	1184.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25S5F@186804|Peptostreptococcaceae	186801|Clostridia	C	Prismane/CO dehydrogenase family	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
HKD1_k127_363461_25	1476973.JMMB01000007_gene602	9.515e-166	524.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25QX1@186804|Peptostreptococcaceae	186801|Clostridia	C	Phosphate acetyl/butaryl transferase	ptb1	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
HKD1_k127_363461_16	1476973.JMMB01000007_gene601	6.58e-199	621.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,25QFT@186804|Peptostreptococcaceae	186801|Clostridia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
HKD1_k127_3662056_7	1280692.AUJL01000005_gene1783	0.0004217	42.0	COG2963@1|root,COG2963@2|Bacteria,1V09A@1239|Firmicutes,24G3Z@186801|Clostridia,36P7N@31979|Clostridiaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
HKD1_k127_3662056_2	1476973.JMMB01000007_gene2723	4.124e-168	531.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,25QR2@186804|Peptostreptococcaceae	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HKD1_k127_3662056_4	272563.CD630_25250	4.282e-97	321.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24KZH@186801|Clostridia,25RI7@186804|Peptostreptococcaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HKD1_k127_3662056_3	1476973.JMMB01000007_gene2721	2.185e-118	383.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25QZS@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD1_k127_3662056_5	1476973.JMMB01000007_gene2720	3.893e-92	305.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,25RIB@186804|Peptostreptococcaceae	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
HKD1_k127_3662056_6	1301100.HG529369_gene1443	1.62e-67	230.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,36KHS@31979|Clostridiaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HKD1_k127_3662056_0	1391646.AVSU01000046_gene1556	4.645e-263	812.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25QI2@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD1_k127_3662056_1	1391646.AVSU01000046_gene1556	4.756e-247	764.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25QI2@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HKD1_k127_3679388_29	1151292.QEW_4519	7.374e-11	64.0	2EIGC@1|root,33C7R@2|Bacteria,1VKK2@1239|Firmicutes	1239|Firmicutes	S	Phage uncharacterised protein (Phage_XkdX)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_XkdX
HKD1_k127_3679388_28	491915.Aflv_0676	6.359e-14	76.0	2E0XH@1|root,32WEA@2|Bacteria,1VDFW@1239|Firmicutes,4HMM9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_11	1027292.HMPREF9372_3340	5.961e-68	249.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CHU_C,SLH
HKD1_k127_3679388_15	500633.CLOHIR_00382	5.633e-52	190.0	COG3778@1|root,COG3778@2|Bacteria,1V53V@1239|Firmicutes,25DQ9@186801|Clostridia,25TPP@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
HKD1_k127_3679388_7	431943.CKL_3249	6.096e-105	352.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,36FT3@31979|Clostridiaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
HKD1_k127_3679388_17	536232.CLM_2507	1.39e-44	166.0	2CDGF@1|root,31F2E@2|Bacteria,1V9UN@1239|Firmicutes,24Q31@186801|Clostridia,36KRP@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
HKD1_k127_3679388_8	536232.CLM_2509	5.101e-104	346.0	2DB96@1|root,2Z7V6@2|Bacteria,1UYVR@1239|Firmicutes,24A1R@186801|Clostridia,36DD4@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_13	536232.CLM_2510	2.591e-60	219.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24MKW@186801|Clostridia,36KAC@31979|Clostridiaceae	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD1_k127_3679388_26	349161.Dred_1215	1.098e-16	96.0	COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,1UJ98@1239|Firmicutes,24BN7@186801|Clostridia	186801|Clostridia	D	Phage tail tape measure protein TP901	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
HKD1_k127_3679388_4	431943.CKL_3255	4.893e-160	545.0	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,36USH@31979|Clostridiaceae	186801|Clostridia	D	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
HKD1_k127_3679388_14	1443122.Z958_p0050	1.567e-55	197.0	2E0UT@1|root,32WC6@2|Bacteria,1VCQF@1239|Firmicutes,24MGU@186801|Clostridia,36JZQ@31979|Clostridiaceae	186801|Clostridia	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
HKD1_k127_3679388_12	536232.CLM_2515	1.314e-64	222.0	2BPYU@1|root,32ISS@2|Bacteria,1V6QM@1239|Firmicutes,25J6P@186801|Clostridia,36JYI@31979|Clostridiaceae	186801|Clostridia	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2001
HKD1_k127_3679388_6	431943.CKL_3262	5.262e-129	427.0	28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,24AS0@186801|Clostridia,36G2R@31979|Clostridiaceae	186801|Clostridia	S	Phage tail sheath protein beta-sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N
HKD1_k127_3679388_27	1443122.Z958_p0047	3.36e-15	77.0	28WR0@1|root,2ZIQQ@2|Bacteria,1W55K@1239|Firmicutes,24UVA@186801|Clostridia,36PGQ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_10	536232.CLM_2518	2.251e-90	304.0	2AUS0@1|root,31KF0@2|Bacteria,1V7UD@1239|Firmicutes,24CIN@186801|Clostridia,36HGJ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_16	290402.Cbei_1644	1.604e-46	171.0	COG5005@1|root,COG5005@2|Bacteria,1VAPF@1239|Firmicutes,24P7A@186801|Clostridia,36KQQ@31979|Clostridiaceae	186801|Clostridia	S	Phage virion morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_19	1033737.CAEV01000076_gene509	5.868e-42	157.0	2A6B6@1|root,30V3W@2|Bacteria,1U1ES@1239|Firmicutes,24SVP@186801|Clostridia,36VEQ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_21	1033737.CAEV01000076_gene510	1.558e-39	149.0	2C6BK@1|root,32SKF@2|Bacteria,1VE8N@1239|Firmicutes,24N75@186801|Clostridia,36M6N@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_3	293826.Amet_2574	2.197e-166	528.0	28HUG@1|root,2Z816@2|Bacteria,1UZGA@1239|Firmicutes,24C8Q@186801|Clostridia,36H6Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_22	1196323.ALKF01000160_gene5087	3.249e-38	146.0	2DRV9@1|root,32URR@2|Bacteria,1V9YE@1239|Firmicutes,4IASK@91061|Bacilli,27344@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2190
HKD1_k127_3679388_2	1033737.CAEV01000076_gene513	1.553e-187	596.0	28JVB@1|root,2Z9KA@2|Bacteria,1TRYF@1239|Firmicutes,24C9B@186801|Clostridia,36HFU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_5	1033737.CAEV01000076_gene516	1.4e-141	456.0	2DBD6@1|root,2Z8I5@2|Bacteria,1UZHS@1239|Firmicutes,248AT@186801|Clostridia,36GSH@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_0	1033737.CAEV01000076_gene517	3.648e-251	782.0	COG3567@1|root,COG3567@2|Bacteria,1UY8W@1239|Firmicutes,249FS@186801|Clostridia,36DV9@31979|Clostridiaceae	186801|Clostridia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
HKD1_k127_3679388_24	218284.CCDN010000001_gene859	7.317e-22	98.0	COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4HF2Y@91061|Bacilli,1ZM6Z@1386|Bacillus	91061|Bacilli	L	Phage terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,Terminase_3
HKD1_k127_3679388_1	1033737.CAEV01000076_gene518	1.498e-208	650.0	COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia,36H5N@31979|Clostridiaceae	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_9	1292035.H476_1020	7.589e-95	316.0	COG5484@1|root,COG5484@2|Bacteria,1V6XI@1239|Firmicutes,24HPQ@186801|Clostridia,25UF2@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA packaging	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,Terminase_5
HKD1_k127_3679388_23	1408823.AXUS01000024_gene2704	7.475e-31	127.0	COG1191@1|root,COG1191@2|Bacteria,1UR0N@1239|Firmicutes,24VH9@186801|Clostridia	186801|Clostridia	K	sigma factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_18	272563.CD630_29310	9.17e-44	164.0	COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,24P18@186801|Clostridia	186801|Clostridia	L	Endodeoxyribonuclease RusA	rusA	-	-	-	-	-	-	-	-	-	-	-	RusA
HKD1_k127_3679388_30	1211817.CCAT010000049_gene2481	7.374e-11	64.0	2BB9Y@1|root,324SP@2|Bacteria,1UQZ4@1239|Firmicutes,24VBZ@186801|Clostridia,36PCV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3679388_25	1301100.HG529418_gene3025	4.696e-20	90.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,36IQ6@31979|Clostridiaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb3	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD1_k127_3679388_20	1476973.JMMB01000007_gene232	7.132e-40	149.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,25RJ7@186804|Peptostreptococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD1_k127_3679388_32	246199.CUS_6113	6.333e-07	59.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD1_k127_3891421_17	1476973.JMMB01000007_gene2556	1.202e-102	337.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia,25SAP@186804|Peptostreptococcaceae	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
HKD1_k127_3891421_28	1476973.JMMB01000007_gene2555	6.891e-41	152.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia,25TT9@186804|Peptostreptococcaceae	186801|Clostridia	N	Bacterial export proteins, family 3	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
HKD1_k127_3891421_2	1476973.JMMB01000007_gene2554	1.454e-318	983.0	COG1377@1|root,COG1684@1|root,COG1377@2|Bacteria,COG1684@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,25SEH@186804|Peptostreptococcaceae	186801|Clostridia	N	Bacterial export proteins, family 1	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
HKD1_k127_3891421_1	1476973.JMMB01000007_gene2553	0.0	1189.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,25SYE@186804|Peptostreptococcaceae	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
HKD1_k127_3891421_16	1476973.JMMB01000007_gene2552	7.999e-115	374.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,25SBP@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-70 region 3	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_3891421_13	1301100.HG529359_gene2135	6.588e-125	404.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,36GJU@31979|Clostridiaceae	186801|Clostridia	N	flagellar basal body	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD1_k127_3891421_15	1476973.JMMB01000007_gene2550	2.186e-122	396.0	COG4786@1|root,COG4786@2|Bacteria,1V4CH@1239|Firmicutes,25DHI@186801|Clostridia,25SRW@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD1_k127_3891421_29	1301100.HG529359_gene2133	3.435e-40	149.0	COG1886@1|root,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,36FD2@31979|Clostridiaceae	186801|Clostridia	N	flagellar motor switch protein	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
HKD1_k127_3891421_9	1476973.JMMB01000007_gene2547	3.138e-176	558.0	COG2020@1|root,COG2020@2|Bacteria,1V4M0@1239|Firmicutes,24JX0@186801|Clostridia,25S2F@186804|Peptostreptococcaceae	186801|Clostridia	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3891421_6	1476973.JMMB01000007_gene2489	1.506e-243	754.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,25QSK@186804|Peptostreptococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HKD1_k127_3891421_4	1476973.JMMB01000007_gene2525	9.1e-282	870.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,25SFP@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD1_k127_3891421_27	1292035.H476_0752	1.417e-45	166.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,25RQG@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
HKD1_k127_3891421_18	1476973.JMMB01000007_gene2522	3.611e-98	322.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25TFT@186804|Peptostreptococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HKD1_k127_3891421_22	1391646.AVSU01000052_gene984	1.129e-58	211.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,25S03@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
HKD1_k127_3891421_3	1476973.JMMB01000007_gene2520	6.444e-318	992.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SSQ@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
HKD1_k127_3891421_19	1304284.L21TH_1085	7.656e-77	263.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,36G8Y@31979|Clostridiaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
HKD1_k127_3891421_8	445973.CLOBAR_01618	1.253e-184	583.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25QNT@186804|Peptostreptococcaceae	186801|Clostridia	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_3891421_21	1301100.HG529303_gene3112	6.376e-65	226.0	COG4871@1|root,COG4871@2|Bacteria,1V7YF@1239|Firmicutes,24KYS@186801|Clostridia,36RWM@31979|Clostridiaceae	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
HKD1_k127_3891421_25	1476973.JMMB01000007_gene2511	2.634e-48	175.0	2F8Y5@1|root,3419Z@2|Bacteria,1VX1X@1239|Firmicutes,251UA@186801|Clostridia,25RZG@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_3891421_11	1476973.JMMB01000007_gene2510	6.29e-144	459.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,25R0Y@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16290	HK
HKD1_k127_3891421_24	1391646.AVSU01000100_gene3400	4.097e-56	201.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,25RKF@186804|Peptostreptococcaceae	186801|Clostridia	S	Thiamine transporter protein (Thia_YuaJ)	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
HKD1_k127_3891421_7	1476973.JMMB01000007_gene1615	1.072e-212	668.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25R63@186804|Peptostreptococcaceae	186801|Clostridia	E	Beta-eliminating lyase	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_3891421_0	1476973.JMMB01000007_gene2504	0.0	1315.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25QP4@186804|Peptostreptococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HKD1_k127_3891421_10	386415.NT01CX_2422	9.09e-165	529.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,36ECS@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HKD1_k127_3891421_5	1487921.DP68_10660	8.091e-274	844.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,36EE1@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
HKD1_k127_3891421_23	1391646.AVSU01000136_gene3321	2.326e-58	204.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD1_k127_3891421_12	1391646.AVSU01000136_gene3322	3.801e-132	424.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,25BYA@186801|Clostridia	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HKD1_k127_3891421_14	1301100.HG529290_gene5180	2.626e-124	401.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,36I5Y@31979|Clostridiaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HKD1_k127_3891421_30	1476973.JMMB01000007_gene2050	2.068e-21	102.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,24IBK@186801|Clostridia,25TGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD1_k127_3891421_20	394503.Ccel_0319	2.387e-67	237.0	2BZ6P@1|root,2Z8AB@2|Bacteria,1TRT3@1239|Firmicutes,247PA@186801|Clostridia,36EGY@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF2935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2935
HKD1_k127_392460_118	1391646.AVSU01000072_gene2936	2.592e-26	108.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25S1G@186804|Peptostreptococcaceae	186801|Clostridia	N	Bacterial flagellin C-terminal helical region	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD1_k127_392460_131	941824.TCEL_01942	0.0003634	47.0	2EVRH@1|root,33P5E@2|Bacteria,1VNTQ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_38	1391646.AVSU01000072_gene2934	2.821e-174	559.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,248Q9@186801|Clostridia,25SY1@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar hook-associated protein 2 N-terminus	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
HKD1_k127_392460_100	1301100.HG529360_gene2122	1.129e-57	202.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia,36JGU@31979|Clostridiaceae	186801|Clostridia	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
HKD1_k127_392460_101	1301100.HG529360_gene2124	4.821e-56	198.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,36JMK@31979|Clostridiaceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
HKD1_k127_392460_57	1476973.JMMB01000007_gene2585	7.584e-135	437.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia,25S3R@186804|Peptostreptococcaceae	186801|Clostridia	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD1_k127_392460_27	1476973.JMMB01000007_gene2586	7.826e-191	604.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia,25S7S@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD1_k127_392460_97	1476973.JMMB01000007_gene2587	1.715e-59	208.0	2ERN0@1|root,33J7F@2|Bacteria,1VMIG@1239|Firmicutes,24MZF@186801|Clostridia,25TM4@186804|Peptostreptococcaceae	186801|Clostridia	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
HKD1_k127_392460_114	1476973.JMMB01000007_gene2588	2.62e-31	124.0	29VEQ@1|root,30GVS@2|Bacteria,1UGRH@1239|Firmicutes,25P9U@186801|Clostridia,25UBB@186804|Peptostreptococcaceae	186801|Clostridia	N	Anti-sigma-28 factor, FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
HKD1_k127_392460_111	1476973.JMMB01000007_gene2589	9.498e-38	144.0	COG1886@1|root,COG1886@2|Bacteria,1UEE6@1239|Firmicutes,25JAH@186801|Clostridia,25U3H@186804|Peptostreptococcaceae	186801|Clostridia	NU	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
HKD1_k127_392460_88	1301100.HG529360_gene2130	9.798e-68	232.0	COG1728@1|root,COG1728@2|Bacteria,1VITC@1239|Firmicutes,24I98@186801|Clostridia,36IWW@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
HKD1_k127_392460_24	1476973.JMMB01000007_gene2591	3.323e-199	628.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25SFE@186804|Peptostreptococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
HKD1_k127_392460_79	1476973.JMMB01000007_gene2592	4.393e-84	285.0	COG3279@1|root,COG3279@2|Bacteria,1UTCF@1239|Firmicutes,252DU@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HKD1_k127_392460_73	1476973.JMMB01000007_gene2593	2.286e-97	322.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,25T36@186804|Peptostreptococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
HKD1_k127_392460_96	1476973.JMMB01000007_gene2594	3.472e-60	214.0	29UDK@1|root,30FQ9@2|Bacteria,1UEEU@1239|Firmicutes,25302@186801|Clostridia,25RUE@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_16	1476973.JMMB01000007_gene2595	3.175e-222	694.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25QFG@186804|Peptostreptococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HKD1_k127_392460_14	1476973.JMMB01000007_gene2596	1.19e-234	743.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25SK2@186804|Peptostreptococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD1_k127_392460_67	883113.HMPREF9708_00976	2.487e-109	359.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,27DKK@186827|Aerococcaceae	91061|Bacilli	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_392460_47	1476973.JMMB01000007_gene2598	9.82e-158	504.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia,25S94@186804|Peptostreptococcaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HKD1_k127_392460_60	1391646.AVSU01000037_gene2065	2.582e-124	400.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25SJA@186804|Peptostreptococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_392460_63	1476973.JMMB01000007_gene2600	1.162e-121	392.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25QSS@186804|Peptostreptococcaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD1_k127_392460_77	1301100.HG529251_gene6267	8.275e-89	295.0	COG2059@1|root,COG2059@2|Bacteria,1V3XK@1239|Firmicutes,25CID@186801|Clostridia,36I35@31979|Clostridiaceae	186801|Clostridia	P	overlaps another CDS with the same product name	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD1_k127_392460_92	1499683.CCFF01000014_gene4072	9.032e-64	223.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,36IGJ@31979|Clostridiaceae	186801|Clostridia	P	Chromate transport protein	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HKD1_k127_392460_15	1301100.HG529362_gene2087	5.339e-223	694.0	COG0416@1|root,COG0416@2|Bacteria,1TPY8@1239|Firmicutes,248BX@186801|Clostridia,36EUZ@31979|Clostridiaceae	186801|Clostridia	I	PFAM fatty acid synthesis plsX protein	grdD	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K21576	-	-	-	-	ko00000,ko01000	-	-	-	FA_synthesis
HKD1_k127_392460_9	1476973.JMMB01000007_gene2603	3.823e-316	970.0	COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,25QHG@186804|Peptostreptococcaceae	186801|Clostridia	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	grdC	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K21577	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III
HKD1_k127_392460_106	1476973.JMMB01000007_gene2604	6.634e-45	164.0	2DMKU@1|root,32S9Z@2|Bacteria,1VB1D@1239|Firmicutes,24MP0@186801|Clostridia,25TXQ@186804|Peptostreptococcaceae	186801|Clostridia	S	selenoprotein B, glycine betaine sarcosine D-proline reductase	-	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD1_k127_392460_18	1476973.JMMB01000007_gene2605	3.338e-213	664.0	COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,25R61@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	grdB	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
HKD1_k127_392460_99	1476973.JMMB01000007_gene2606	1.857e-58	203.0	2AE14@1|root,313TT@2|Bacteria,1V6GX@1239|Firmicutes,24K4C@186801|Clostridia,25TMB@186804|Peptostreptococcaceae	186801|Clostridia	C	Glycine reductase complex selenoprotein A	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
HKD1_k127_392460_121	1476973.JMMB01000007_gene2607	3.031e-21	93.0	2DR3E@1|root,33A02@2|Bacteria,1VKEX@1239|Firmicutes,24UH8@186801|Clostridia,25UB4@186804|Peptostreptococcaceae	186801|Clostridia	S	glycine sarcosine betaine reductase complex protein A	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
HKD1_k127_392460_10	1476973.JMMB01000007_gene2608	1.892e-275	850.0	28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,25QXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Glycine/sarcosine/betaine reductase component B subunits	grdE	-	1.21.4.2	ko:K10671	-	-	-	-	ko00000,ko01000	-	-	-	Gly_reductase
HKD1_k127_392460_98	1476973.JMMB01000007_gene2609	1.26e-58	203.0	COG3118@1|root,COG3118@2|Bacteria,1UHX3@1239|Firmicutes,24JPM@186801|Clostridia,25RVE@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_392460_31	1301100.HG529362_gene2095	1.629e-187	588.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,36E0J@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HKD1_k127_392460_89	1301100.HG529362_gene2096	1.7e-67	230.0	2E36T@1|root,32Y6H@2|Bacteria,1VEXQ@1239|Firmicutes,24RAE@186801|Clostridia,36KR8@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	grdX	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_8	1476973.JMMB01000007_gene2612	0.0	1007.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,25QKD@186804|Peptostreptococcaceae	186801|Clostridia	E	Oligoendopeptidase, M3 family	pz-A	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
HKD1_k127_392460_50	1301100.HG529362_gene2099	3.629e-147	469.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,36F52@31979|Clostridiaceae	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HKD1_k127_392460_128	610130.Closa_2911	3.059e-06	53.0	2F9UY@1|root,30G4N@2|Bacteria,1UF6A@1239|Firmicutes,25K77@186801|Clostridia,223CK@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_124	1163671.JAGI01000002_gene3602	1.359e-08	60.0	2F90J@1|root,341C9@2|Bacteria,1VY39@1239|Firmicutes,24U5D@186801|Clostridia,36NYG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_36	1415774.U728_230	1.259e-181	586.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,24CSU@186801|Clostridia,36G68@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
HKD1_k127_392460_126	431943.CKL_2480	1.764e-07	57.0	2F4IQ@1|root,33X8D@2|Bacteria,1VW34@1239|Firmicutes,24N2X@186801|Clostridia,36NRM@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_123	431943.CKL_2481	5.627e-12	69.0	2FASN@1|root,34300@2|Bacteria,1VY0I@1239|Firmicutes,24R8V@186801|Clostridia,36PG0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_108	1211817.CCAT010000083_gene1406	2.582e-39	158.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794
HKD1_k127_392460_113	1211817.CCAT010000015_gene3737	1.629e-33	142.0	2E6T6@1|root,331D4@2|Bacteria,1V67D@1239|Firmicutes,24Q8P@186801|Clostridia,36SAY@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794
HKD1_k127_392460_120	871968.DESME_03085	2.959e-21	105.0	2E6T6@1|root,331D4@2|Bacteria,1VZ4B@1239|Firmicutes,25GH6@186801|Clostridia,266BC@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794
HKD1_k127_392460_49	1391646.AVSU01000016_gene3164	5.435e-157	501.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
HKD1_k127_392460_81	1391646.AVSU01000016_gene3162	4.107e-77	270.0	COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,24HWM@186801|Clostridia	186801|Clostridia	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
HKD1_k127_392460_71	748727.CLJU_c05500	1.577e-100	340.0	COG1670@1|root,COG1861@1|root,COG1670@2|Bacteria,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,24B0X@186801|Clostridia,36GFB@31979|Clostridiaceae	186801|Clostridia	M	Cytidylyltransferase	spsF	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
HKD1_k127_392460_32	545243.BAEV01000045_gene3556	1.105e-186	590.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36ENR@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
HKD1_k127_392460_37	1443122.Z958_08255	1.223e-177	560.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,36VQ0@31979|Clostridiaceae	186801|Clostridia	M	biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
HKD1_k127_392460_30	1476973.JMMB01000007_gene2616	5.211e-188	594.0	COG1357@1|root,COG1357@2|Bacteria,1VDTQ@1239|Firmicutes,24D3P@186801|Clostridia,25RAM@186804|Peptostreptococcaceae	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_4
HKD1_k127_392460_94	1301100.HG529362_gene2104	4.188e-62	218.0	2F63S@1|root,33YN2@2|Bacteria,1VX5Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_112	1476973.JMMB01000007_gene2618	1.146e-33	133.0	2DRR0@1|root,33CPP@2|Bacteria,1VKKD@1239|Firmicutes,25JBP@186801|Clostridia,25RVF@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD1_k127_392460_19	1476973.JMMB01000007_gene2619	6.111e-208	649.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,25R87@186804|Peptostreptococcaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
HKD1_k127_392460_68	1476973.JMMB01000007_gene2620	4.607e-106	346.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,25R8W@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
HKD1_k127_392460_3	1476973.JMMB01000007_gene2621	0.0	1172.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,25QVE@186804|Peptostreptococcaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_10,Fer4_6,Fer4_9,POR_N,TPP_enzyme_C
HKD1_k127_392460_13	1476973.JMMB01000007_gene2622	1.032e-255	790.0	COG1448@1|root,COG1448@2|Bacteria,1TRJV@1239|Firmicutes,24BZV@186801|Clostridia,25R16@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_392460_6	1476973.JMMB01000007_gene2623	0.0	1054.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25S8T@186804|Peptostreptococcaceae	186801|Clostridia	KT	Propionate catabolism activator	-	-	-	ko:K02688	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PrpR_N,Sigma54_activat
HKD1_k127_392460_69	1476973.JMMB01000007_gene2624	8.767e-104	340.0	COG2968@1|root,COG2968@2|Bacteria,1UEWP@1239|Firmicutes,25JW4@186801|Clostridia,25TMW@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HKD1_k127_392460_86	1476973.JMMB01000007_gene2625	1.023e-69	237.0	2F3YQ@1|root,33WQN@2|Bacteria,1VVFW@1239|Firmicutes,24NI0@186801|Clostridia,25TII@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3785
HKD1_k127_392460_59	1476973.JMMB01000007_gene2626	6.393e-128	415.0	COG0744@1|root,COG0744@2|Bacteria,1V3CG@1239|Firmicutes,24QD2@186801|Clostridia,25R42@186804|Peptostreptococcaceae	186801|Clostridia	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
HKD1_k127_392460_117	1391646.AVSU01000027_gene2378	5.353e-30	118.0	COG2221@1|root,COG2221@2|Bacteria,1UHV8@1239|Firmicutes,25E3Z@186801|Clostridia,25RZA@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HKD1_k127_392460_82	1476973.JMMB01000007_gene2628	4.21e-76	257.0	28X8N@1|root,2ZJ6S@2|Bacteria,1W2SB@1239|Firmicutes,251I1@186801|Clostridia,25UDZ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_21	1476973.JMMB01000007_gene2629	1.22e-204	639.0	COG0515@1|root,COG0515@2|Bacteria,1V311@1239|Firmicutes,250JE@186801|Clostridia,25QG8@186804|Peptostreptococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HKD1_k127_392460_72	1301100.HG529364_gene2862	1.144e-97	320.0	COG0847@1|root,COG0847@2|Bacteria,1UJK1@1239|Firmicutes	1239|Firmicutes	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HKD1_k127_392460_122	1476973.JMMB01000007_gene2111	6.397e-18	93.0	2BPM4@1|root,32IE5@2|Bacteria,1UF3E@1239|Firmicutes,25K48@186801|Clostridia,25UBC@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_44	1476973.JMMB01000007_gene2632	2.82e-164	523.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,25SWZ@186804|Peptostreptococcaceae	186801|Clostridia	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HKD1_k127_392460_53	1476973.JMMB01000007_gene2633	5.641e-139	447.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,25SCD@186804|Peptostreptococcaceae	186801|Clostridia	D	FtsX-like permease family	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HKD1_k127_392460_90	1158612.I580_01768	6.911e-67	234.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,4B0C2@81852|Enterococcaceae	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HKD1_k127_392460_40	1476973.JMMB01000007_gene2635	6.557e-174	549.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,25R5Q@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
HKD1_k127_392460_25	1476973.JMMB01000007_gene2636	1.685e-197	621.0	COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes,24GQA@186801|Clostridia,25SKC@186804|Peptostreptococcaceae	186801|Clostridia	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
HKD1_k127_392460_33	1476973.JMMB01000007_gene2637	1.306e-185	584.0	COG5018@1|root,COG5018@2|Bacteria,1VRJI@1239|Firmicutes,25DMK@186801|Clostridia,25R6S@186804|Peptostreptococcaceae	186801|Clostridia	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HKD1_k127_392460_39	1391646.AVSU01000110_gene693	6.246e-174	546.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25QJY@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
HKD1_k127_392460_116	1476973.JMMB01000007_gene2639	3.805e-30	119.0	297CP@1|root,2ZUK7@2|Bacteria,1W4VB@1239|Firmicutes,252MN@186801|Clostridia,25RWJ@186804|Peptostreptococcaceae	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
HKD1_k127_392460_104	1476973.JMMB01000007_gene2640	6.412e-46	166.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,25RN5@186804|Peptostreptococcaceae	186801|Clostridia	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HKD1_k127_392460_64	1476973.JMMB01000007_gene2641	6.317e-115	371.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25SCP@186804|Peptostreptococcaceae	186801|Clostridia	P	Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HKD1_k127_392460_105	1476973.JMMB01000007_gene1721	6.629e-46	168.0	2E6A2@1|root,3182Z@2|Bacteria,1V931@1239|Firmicutes,25JW0@186801|Clostridia,25TMK@186804|Peptostreptococcaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HKD1_k127_392460_7	1476973.JMMB01000007_gene1855	0.0	1030.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,25QKV@186804|Peptostreptococcaceae	186801|Clostridia	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HKD1_k127_392460_93	1476973.JMMB01000007_gene2643	2.956e-62	216.0	28U5A@1|root,2ZGB5@2|Bacteria,1W3JZ@1239|Firmicutes,251AK@186801|Clostridia,25RXR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_42	1301100.HG529365_gene1368	9.053e-170	540.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,36FQG@31979|Clostridiaceae	186801|Clostridia	M	PFAM NLP P60 protein	-	-	-	ko:K11060,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02042	-	-	-	NLPC_P60,SH3_3
HKD1_k127_392460_84	1301100.HG529365_gene1369	1.364e-74	252.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,36IQU@31979|Clostridiaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HKD1_k127_392460_70	1476973.JMMB01000007_gene2644	9.477e-102	334.0	2BDD8@1|root,32724@2|Bacteria,1USY0@1239|Firmicutes,2509G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_1	1476973.JMMB01000007_gene2645	0.0	1353.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25QNI@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA topoisomerase	topB1	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HKD1_k127_392460_102	1476973.JMMB01000007_gene2646	3.432e-48	173.0	COG1933@1|root,COG1933@2|Bacteria,1VZYR@1239|Firmicutes,251HK@186801|Clostridia,25U3X@186804|Peptostreptococcaceae	186801|Clostridia	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
HKD1_k127_392460_0	1476973.JMMB01000007_gene2647	0.0	1612.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25QN3@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HKD1_k127_392460_45	1476973.JMMB01000007_gene2648	6.497e-160	506.0	COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,249ID@186801|Clostridia,25R1S@186804|Peptostreptococcaceae	186801|Clostridia	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
HKD1_k127_392460_65	1476973.JMMB01000007_gene2649	2.99e-114	370.0	COG2905@1|root,COG2905@2|Bacteria,1UHXF@1239|Firmicutes,25E6D@186801|Clostridia,25QFP@186804|Peptostreptococcaceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	ccpN	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_11
HKD1_k127_392460_2	1476973.JMMB01000007_gene2650	0.0	1246.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,25R5C@186804|Peptostreptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
HKD1_k127_392460_28	1476973.JMMB01000007_gene2651	9.014e-191	596.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,25R89@186804|Peptostreptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase alpha	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
HKD1_k127_392460_95	1391646.AVSU01000026_gene2361	5.021e-62	219.0	COG1308@1|root,COG1308@2|Bacteria,1V7I9@1239|Firmicutes,24M6Q@186801|Clostridia,25RXG@186804|Peptostreptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
HKD1_k127_392460_54	1476973.JMMB01000007_gene2653	9.918e-139	443.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25R8U@186804|Peptostreptococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HKD1_k127_392460_12	1476973.JMMB01000007_gene2654	8.738e-259	801.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25QJE@186804|Peptostreptococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HKD1_k127_392460_26	1476973.JMMB01000007_gene2655	3.86e-196	612.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,25QEP@186804|Peptostreptococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HKD1_k127_392460_109	1286171.EAL2_c14270	2.582e-38	147.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,25WWH@186806|Eubacteriaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
HKD1_k127_392460_61	1476973.JMMB01000007_gene2657	8.972e-124	400.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,25QEG@186804|Peptostreptococcaceae	186801|Clostridia	IM	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
HKD1_k127_392460_76	1476973.JMMB01000007_gene2658	1.795e-89	296.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,25RAP@186804|Peptostreptococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
HKD1_k127_392460_17	1476973.JMMB01000007_gene2659	4.551e-222	694.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,25QW8@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HKD1_k127_392460_110	1476973.JMMB01000007_gene2660	4.049e-38	143.0	2B7WQ@1|root,3213N@2|Bacteria,1W16G@1239|Firmicutes,25JBY@186801|Clostridia,25RW6@186804|Peptostreptococcaceae	186801|Clostridia	S	YabP family	-	-	-	-	-	-	-	-	-	-	-	-	YabP
HKD1_k127_392460_58	1476973.JMMB01000007_gene2661	3.349e-130	423.0	2BCIE@1|root,3264D@2|Bacteria,1US3H@1239|Firmicutes,24YCT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_83	1476973.JMMB01000007_gene2662	1.329e-75	258.0	COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,24MTF@186801|Clostridia,25TBG@186804|Peptostreptococcaceae	186801|Clostridia	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
HKD1_k127_392460_87	1476973.JMMB01000007_gene2663	1.265e-69	238.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,25RGV@186804|Peptostreptococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HKD1_k127_392460_119	1391646.AVSU01000026_gene2373	5.252e-26	109.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HKD1_k127_392460_91	1301100.HG529365_gene1393	5.86e-64	220.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,36JIP@31979|Clostridiaceae	186801|Clostridia	FG	Hit family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HKD1_k127_392460_11	1301100.HG529365_gene1394	1.199e-261	808.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,36DS5@31979|Clostridiaceae	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD1_k127_392460_66	1408823.AXUS01000003_gene483	1.24e-112	368.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,25QMC@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HKD1_k127_392460_35	1476973.JMMB01000007_gene2668	6.556e-183	574.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,25R0W@186804|Peptostreptococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HKD1_k127_392460_103	1476973.JMMB01000007_gene1628	6.188e-47	170.0	2DKJD@1|root,309PU@2|Bacteria,1U5GD@1239|Firmicutes,25JDZ@186801|Clostridia,25TXT@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD1_k127_392460_75	1292035.H476_2325	3.715e-97	323.0	29N9N@1|root,3097H@2|Bacteria,1UFNT@1239|Firmicutes,24HXU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_80	1476973.JMMB01000007_gene2671	9.154e-83	278.0	29UN1@1|root,30FZM@2|Bacteria,1UEXI@1239|Firmicutes,250E5@186801|Clostridia,25TQW@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_48	272563.CD630_01990	2.067e-157	509.0	COG0737@1|root,COG0737@2|Bacteria,1VTIP@1239|Firmicutes	1239|Firmicutes	F	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_392460_46	1286171.EAL2_c14410	1.404e-159	511.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25UX4@186806|Eubacteriaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HKD1_k127_392460_5	1476973.JMMB01000007_gene2675	0.0	1119.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25R5Y@186804|Peptostreptococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD1_k127_392460_78	1476973.JMMB01000007_gene2676	3.498e-87	291.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,25R93@186804|Peptostreptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HKD1_k127_392460_29	1301100.HG529365_gene1419	7.169e-190	596.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,36DW8@31979|Clostridiaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HKD1_k127_392460_23	1476973.JMMB01000007_gene2678	3.908e-201	631.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,25R4C@186804|Peptostreptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HKD1_k127_392460_4	1476973.JMMB01000007_gene2680	0.0	1165.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,25QKW@186804|Peptostreptococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HKD1_k127_392460_115	1476973.JMMB01000007_gene2681	8.052e-31	123.0	28XYG@1|root,2ZJUD@2|Bacteria,1W2IX@1239|Firmicutes,255XM@186801|Clostridia,25UE9@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_56	1301100.HG529367_gene1337	3.654e-136	439.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,36F21@31979|Clostridiaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HKD1_k127_392460_34	1476973.JMMB01000007_gene2683	3.297e-185	581.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,25QFX@186804|Peptostreptococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HKD1_k127_392460_107	1476973.JMMB01000007_gene2684	2.877e-40	151.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25RNU@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HKD1_k127_392460_41	272563.CD630_24740	5.387e-171	541.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25QPQ@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HKD1_k127_392460_22	1476973.JMMB01000007_gene2686	1.591e-201	634.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,25UKE@186804|Peptostreptococcaceae	186801|Clostridia	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
HKD1_k127_392460_20	1476973.JMMB01000007_gene2687	6.079e-205	642.0	COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,24AP4@186801|Clostridia,25RCF@186804|Peptostreptococcaceae	186801|Clostridia	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
HKD1_k127_392460_43	1476973.JMMB01000007_gene2688	2.534e-164	520.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25QVR@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
HKD1_k127_392460_51	1476973.JMMB01000007_gene2689	1.88e-144	461.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25R82@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
HKD1_k127_392460_52	1476973.JMMB01000007_gene2690	1.968e-139	444.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,25R6Y@186804|Peptostreptococcaceae	186801|Clostridia	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HKD1_k127_392460_85	1301100.HG529367_gene1347	1.962e-74	258.0	2BDUS@1|root,327IR@2|Bacteria,1UTF3@1239|Firmicutes,252QF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_392460_55	1476973.JMMB01000007_gene2701	1.14e-136	440.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,25SGS@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF348)	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
HKD1_k127_392460_62	1476973.JMMB01000007_gene2703	2.347e-123	397.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,25QHN@186804|Peptostreptococcaceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HKD1_k127_392460_74	272563.CD630_14920	2.486e-97	347.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,25SKU@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,MASE3,PAS,PAS_8,PAS_9
HKD1_k127_4022201_3	1476973.JMMB01000007_gene2742	1.16e-215	671.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25QS2@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD1_k127_4022201_6	1301100.HG529369_gene1472	1.865e-130	418.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,36DKZ@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HKD1_k127_4022201_11	1476973.JMMB01000007_gene2744	1.264e-100	330.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,25R8Q@186804|Peptostreptococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HKD1_k127_4022201_4	1476973.JMMB01000007_gene2745	1.056e-196	614.0	COG1245@1|root,COG2878@1|root,COG1245@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25QGD@186804|Peptostreptococcaceae	186801|Clostridia	C	Electron transport complex	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
HKD1_k127_4022201_10	1476973.JMMB01000007_gene2746	1.583e-102	335.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,25QD3@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
HKD1_k127_4022201_9	1476973.JMMB01000007_gene2747	9.986e-108	350.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
HKD1_k127_4022201_14	1476973.JMMB01000007_gene2748	6.76e-85	284.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,25RCW@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
HKD1_k127_4022201_5	1476973.JMMB01000007_gene2749	3.027e-191	599.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,25QVJ@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
HKD1_k127_4022201_1	1476973.JMMB01000007_gene2750	2.789e-269	831.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25QF7@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
HKD1_k127_4022201_8	1476973.JMMB01000007_gene2751	2.808e-112	372.0	2EX5K@1|root,33QGM@2|Bacteria,1VU5V@1239|Firmicutes,25JGA@186801|Clostridia,25SET@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4022201_7	1476973.JMMB01000007_gene2752	2.535e-125	404.0	COG3568@1|root,COG3568@2|Bacteria,1V9H0@1239|Firmicutes,24KPC@186801|Clostridia,25QDX@186804|Peptostreptococcaceae	186801|Clostridia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD1_k127_4022201_12	1476973.JMMB01000007_gene2753	5.175e-100	329.0	2EXDK@1|root,33QQ6@2|Bacteria,1VT54@1239|Firmicutes,24XHK@186801|Clostridia,25RDN@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4022201_18	1476973.JMMB01000007_gene2757	3.328e-29	118.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,25JB4@186801|Clostridia,25RTN@186804|Peptostreptococcaceae	186801|Clostridia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HKD1_k127_4022201_21	1123503.KB908064_gene1124	0.0008326	44.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2KH7K@204458|Caulobacterales	204458|Caulobacterales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_4022201_2	1476973.JMMB01000007_gene2758	1.136e-250	783.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,25RDV@186804|Peptostreptococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HKD1_k127_4022201_17	1476973.JMMB01000007_gene2759	4.052e-73	250.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,25RGI@186804|Peptostreptococcaceae	186801|Clostridia	M	Transglycosylase SLT domain protein	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
HKD1_k127_4022201_13	1476973.JMMB01000007_gene2760	7.899e-95	314.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,25RFB@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HKD1_k127_4022201_0	1476973.JMMB01000007_gene2761	0.0	1507.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25QCY@186804|Peptostreptococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HKD1_k127_4022201_15	1391646.AVSU01000118_gene1350	2.71e-83	282.0	28PHV@1|root,2ZC86@2|Bacteria,1VCIE@1239|Firmicutes,25DCV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4022201_19	1301100.HG529370_gene1427	5.058e-25	106.0	2947A@1|root,2ZRMP@2|Bacteria,1W1JW@1239|Firmicutes,24R4T@186801|Clostridia,36MS9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4022201_16	1151292.QEW_1482	3.05e-74	250.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_4062274_23	641107.CDLVIII_3095	9.851e-54	202.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,36UU1@31979|Clostridiaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_4062274_19	1499683.CCFF01000017_gene2346	9.577e-89	303.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_4062274_10	1292035.H476_0607	1.991e-133	442.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,25R0J@186804|Peptostreptococcaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_4062274_1	1476973.JMMB01000007_gene1271	2.161e-222	692.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25QE4@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
HKD1_k127_4062274_8	1476973.JMMB01000007_gene1272	1.43e-158	505.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25R2P@186804|Peptostreptococcaceae	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HKD1_k127_4062274_3	1476973.JMMB01000007_gene1273	6.27e-207	646.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,25QSI@186804|Peptostreptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
HKD1_k127_4062274_15	1301100.HG529275_gene1645	6.926e-108	353.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,36JT4@31979|Clostridiaceae	186801|Clostridia	M	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HKD1_k127_4062274_14	1476973.JMMB01000007_gene724	4.197e-113	368.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25SG4@186804|Peptostreptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
HKD1_k127_4062274_12	1476973.JMMB01000007_gene725	8.566e-128	410.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,25SPU@186804|Peptostreptococcaceae	186801|Clostridia	M	Bacterial sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HKD1_k127_4062274_13	1151292.QEW_0251	5.77e-120	391.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HKD1_k127_4062274_9	1151292.QEW_0252	2.522e-157	499.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25T2V@186804|Peptostreptococcaceae	186801|Clostridia	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD1_k127_4062274_16	1294142.CINTURNW_0474	1.149e-107	350.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,36DWD@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
HKD1_k127_4062274_4	1410626.JHXB01000004_gene189	7.049e-194	607.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,27ICF@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Male sterility protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HKD1_k127_4062274_31	575593.HMPREF0491_02846	6.341e-17	92.0	COG1216@1|root,COG1216@2|Bacteria,1VAE1@1239|Firmicutes,24J53@186801|Clostridia,27TA7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_4062274_20	1195236.CTER_1976	1.609e-66	243.0	COG3307@1|root,COG3307@2|Bacteria,1UJAI@1239|Firmicutes,247MI@186801|Clostridia	186801|Clostridia	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4062274_17	545243.BAEV01000056_gene207	4.146e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia,36I9R@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_4062274_5	1262449.CP6013_0792	2.325e-183	580.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,36FM6@31979|Clostridiaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glyco_transf_4,Glycos_transf_1
HKD1_k127_4062274_22	1229485.AMYV01000004_gene2311	9.647e-57	203.0	COG1216@1|root,COG1216@2|Bacteria,1QTEK@1224|Proteobacteria,1S5EC@1236|Gammaproteobacteria,1JAWJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl transferase family 2	rfbF	-	-	ko:K12990	ko02024,ko02025,map02024,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HKD1_k127_4062274_0	1476973.JMMB01000007_gene733	7.366e-259	805.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,25R0J@186804|Peptostreptococcaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_4062274_29	1301100.HG529277_gene1664	6.934e-27	110.0	COG1087@1|root,COG1087@2|Bacteria	2|Bacteria	M	UDP-glucose 4-epimerase activity	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD1_k127_4062274_7	1476973.JMMB01000007_gene734	1.397e-167	530.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,25SU1@186804|Peptostreptococcaceae	186801|Clostridia	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD1_k127_4062274_32	203123.OEOE_0686	1.166e-14	83.0	2B0Y6@1|root,31TB7@2|Bacteria,1V6RK@1239|Firmicutes,4HK0B@91061|Bacilli,4AY86@81850|Leuconostocaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4062274_25	1280689.AUJC01000006_gene2754	3.019e-41	162.0	2FDGH@1|root,345I3@2|Bacteria,1VZV3@1239|Firmicutes,252VG@186801|Clostridia,36SN3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4062274_6	1476973.JMMB01000007_gene735	4.238e-170	538.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25T3D@186804|Peptostreptococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD1_k127_4062274_28	1391646.AVSU01000117_gene833	3.23e-32	130.0	28PTP@1|root,335EY@2|Bacteria,1VZWA@1239|Firmicutes,24W4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4062274_21	1476973.JMMB01000007_gene736	1.077e-63	223.0	COG4767@1|root,COG4767@2|Bacteria,1UXE1@1239|Firmicutes,25JGQ@186801|Clostridia,25TWX@186804|Peptostreptococcaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD1_k127_4062274_11	641107.CDLVIII_5654	2.857e-131	436.0	COG5279@1|root,COG5492@1|root,COG5279@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2,Transglut_core
HKD1_k127_4062274_18	1476973.JMMB01000007_gene2169	1.79e-89	302.0	2DM8X@1|root,32758@2|Bacteria,1VD0R@1239|Firmicutes,24IUX@186801|Clostridia,25TSH@186804|Peptostreptococcaceae	186801|Clostridia	S	Conserved phage C-terminus (Phg_2220_C)	-	-	-	-	-	-	-	-	-	-	-	-	Phg_2220_C
HKD1_k127_4062274_2	1476973.JMMB01000007_gene2168	1.422e-213	670.0	COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae	186801|Clostridia	L	DnaB-like helicase N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
HKD1_k127_4062274_26	1476973.JMMB01000007_gene2163	3.85e-36	138.0	COG5566@1|root,COG5566@2|Bacteria,1VNYR@1239|Firmicutes,2535W@186801|Clostridia,25UDG@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_4062274_30	796940.HMPREF9628_01218	9.066e-19	99.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25R6Z@186804|Peptostreptococcaceae	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_4062274_24	1216932.CM240_0443	2.337e-48	181.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4062274_33	742735.HMPREF9467_01252	3.906e-07	61.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,21XKF@1506553|Lachnoclostridium	186801|Clostridia	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD1_k127_4062274_27	1476973.JMMB01000007_gene2168	5.692e-35	135.0	COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae	186801|Clostridia	L	DnaB-like helicase N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
HKD1_k127_4082291_10	1292035.H476_2252	1.245e-228	713.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_4082291_32	1476973.JMMB01000007_gene2776	9.036e-89	298.0	2CHCT@1|root,3401K@2|Bacteria,1VXY2@1239|Firmicutes,250E3@186801|Clostridia,25RX5@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_19	1476973.JMMB01000007_gene2777	2.648e-170	537.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,25SCJ@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_4082291_6	1476973.JMMB01000007_gene2778	5.112e-286	880.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,25QU6@186804|Peptostreptococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
HKD1_k127_4082291_46	1476973.JMMB01000007_gene2779	5.952e-28	113.0	COG4224@1|root,COG4224@2|Bacteria,1UEG3@1239|Firmicutes,25JD1@186801|Clostridia,25RZX@186804|Peptostreptococcaceae	186801|Clostridia	S	UPF0291 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF896
HKD1_k127_4082291_7	1476973.JMMB01000007_gene2780	2.143e-266	826.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25QSF@186804|Peptostreptococcaceae	186801|Clostridia	K	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
HKD1_k127_4082291_22	1476973.JMMB01000007_gene2781	1.688e-157	498.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25R4U@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HKD1_k127_4082291_15	272563.CD630_10680	3.726e-193	611.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25R7A@186804|Peptostreptococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD1_k127_4082291_31	1476973.JMMB01000007_gene2784	7.685e-104	340.0	2BDF4@1|root,32746@2|Bacteria,1UT03@1239|Firmicutes,250MA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_25	1301100.HG529371_gene1425	6.75e-133	434.0	2CHCU@1|root,33S16@2|Bacteria,1VSBC@1239|Firmicutes,24Y8S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_16	1476973.JMMB01000007_gene2787	8.068e-187	587.0	2DZXK@1|root,32VMK@2|Bacteria,1VBXX@1239|Firmicutes,24MJB@186801|Clostridia,25REV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_29	1476973.JMMB01000007_gene2788	1.258e-109	360.0	2F1KM@1|root,33UM1@2|Bacteria,1VUEM@1239|Firmicutes,24Y42@186801|Clostridia,25RCR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_37	1476973.JMMB01000007_gene2789	3.447e-49	180.0	2B7T0@1|root,320ZG@2|Bacteria,1UEEB@1239|Firmicutes,252D6@186801|Clostridia,25RR0@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_27	1476973.JMMB01000007_gene2790	2.932e-110	359.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,25QJQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
HKD1_k127_4082291_8	1476973.JMMB01000007_gene2791	1.92e-248	769.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,25R7K@186804|Peptostreptococcaceae	186801|Clostridia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
HKD1_k127_4082291_18	1476973.JMMB01000007_gene2792	4.856e-180	565.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,25QZQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
HKD1_k127_4082291_3	1476973.JMMB01000007_gene2793	0.0	1317.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,25R5J@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
HKD1_k127_4082291_5	1301100.HG529374_gene1510	2.43e-299	922.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,36DCC@31979|Clostridiaceae	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
HKD1_k127_4082291_13	1476973.JMMB01000007_gene2795	4.912e-200	625.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25QZA@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	ccpA	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HKD1_k127_4082291_45	1476973.JMMB01000007_gene2797	1.035e-29	118.0	2CK5R@1|root,2ZXQ2@2|Bacteria,1W6P1@1239|Firmicutes,256IB@186801|Clostridia,25RV4@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_47	1476973.JMMB01000007_gene2798	3.018e-24	102.0	2CK5R@1|root,3249M@2|Bacteria,1UF3W@1239|Firmicutes,25K4P@186801|Clostridia,25UCV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_39	1476973.JMMB01000007_gene2799	7.298e-44	159.0	2CK5R@1|root,2ZPHT@2|Bacteria,1W6KH@1239|Firmicutes,252MA@186801|Clostridia,25U9A@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_43	1301100.HG529374_gene1519	1.736e-31	124.0	2BE0Y@1|root,327RI@2|Bacteria,1UTN0@1239|Firmicutes,253KI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_44	1476973.JMMB01000007_gene2801	2.117e-30	122.0	2CK5S@1|root,2ZUEE@2|Bacteria,1W4P1@1239|Firmicutes,256YK@186801|Clostridia,25RSQ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_36	1301100.HG529375_gene4035	5.492e-51	184.0	2F7IZ@1|root,33ZZJ@2|Bacteria,1VXHC@1239|Firmicutes,252JH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_42	1476973.JMMB01000007_gene2803	1.395e-31	124.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,25RUU@186804|Peptostreptococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD1_k127_4082291_41	1476973.JMMB01000007_gene2804	5.223e-39	145.0	2BE4J@1|root,327V8@2|Bacteria,1UTSA@1239|Firmicutes,25446@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_24	1391646.AVSU01000075_gene2820	3.506e-147	470.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25QRC@186804|Peptostreptococcaceae	186801|Clostridia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD1_k127_4082291_33	1410653.JHVC01000002_gene4373	2.643e-70	243.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,36I0R@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
HKD1_k127_4082291_21	1511.CLOST_0101	2.127e-166	525.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25QP3@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HKD1_k127_4082291_14	1301100.HG529375_gene4038	2.236e-198	620.0	COG3081@1|root,COG3081@2|Bacteria,1V278@1239|Firmicutes,249YK@186801|Clostridia,36DIZ@31979|Clostridiaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
HKD1_k127_4082291_20	1301100.HG529375_gene4039	1.204e-166	527.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,36EBK@31979|Clostridiaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluA	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
HKD1_k127_4082291_23	1476973.JMMB01000007_gene2807	5.975e-150	476.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,25R3I@186804|Peptostreptococcaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
HKD1_k127_4082291_28	1476973.JMMB01000007_gene2808	9.101e-110	356.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,25RCI@186804|Peptostreptococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD1_k127_4082291_9	1391646.AVSU01000002_gene10	2.144e-236	734.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,25SAM@186804|Peptostreptococcaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
HKD1_k127_4082291_11	1476973.JMMB01000007_gene2810	7.038e-221	689.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25QXD@186804|Peptostreptococcaceae	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD1_k127_4082291_26	1301100.HG529375_gene4044	2.118e-126	407.0	COG1251@1|root,COG1251@2|Bacteria,1UZNP@1239|Firmicutes,24951@186801|Clostridia,36EU4@31979|Clostridiaceae	186801|Clostridia	C	reductase	-	-	-	-	-	-	-	-	-	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD1_k127_4082291_2	1476973.JMMB01000007_gene2811	0.0	1619.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25QCK@186804|Peptostreptococcaceae	186801|Clostridia	L	Exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HKD1_k127_4082291_17	1408823.AXUS01000029_gene1653	1.008e-181	576.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25QNP@186804|Peptostreptococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HKD1_k127_4082291_40	1476973.JMMB01000007_gene704	3.903e-40	152.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia,25UCN@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
HKD1_k127_4082291_0	1476973.JMMB01000007_gene2825	0.0	2288.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,25QHM@186804|Peptostreptococcaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HKD1_k127_4082291_1	1476973.JMMB01000007_gene2826	0.0	2156.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,25QGR@186804|Peptostreptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HKD1_k127_4082291_35	748727.CLJU_c28390	1.015e-52	195.0	COG2887@1|root,COG2887@2|Bacteria,1V0G5@1239|Firmicutes,24E3P@186801|Clostridia,36JM9@31979|Clostridiaceae	186801|Clostridia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
HKD1_k127_4082291_4	1476973.JMMB01000007_gene2828	0.0	1312.0	COG0210@1|root,COG0210@2|Bacteria,1UQI9@1239|Firmicutes,24BXT@186801|Clostridia,25QSC@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD1_k127_4082291_12	1292035.H476_1958	1.353e-206	661.0	COG0210@1|root,COG0210@2|Bacteria,1V0R3@1239|Firmicutes,24820@186801|Clostridia,25QTN@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_30	796940.HMPREF9628_00934	7.423e-106	353.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,25QPN@186804|Peptostreptococcaceae	186801|Clostridia	S	Phosphotransferase system, EIIC	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
HKD1_k127_4082291_38	926561.KB900618_gene421	3.051e-44	167.0	COG3650@1|root,COG3650@2|Bacteria,1V96I@1239|Firmicutes,24HFD@186801|Clostridia	186801|Clostridia	S	response to hydrogen peroxide	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_50	1052684.PPM_4347	0.0001025	46.0	2EAB1@1|root,334F9@2|Bacteria,1VGT1@1239|Firmicutes,4HPBJ@91061|Bacilli,26VWN@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4082291_34	1476973.JMMB01000007_gene2830	6.356e-67	230.0	2996N@1|root,2ZW9Z@2|Bacteria,1W3BT@1239|Firmicutes,256EI@186801|Clostridia,25TZF@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_411298_7	1487921.DP68_03385	1.138e-87	291.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,36DVN@31979|Clostridiaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
HKD1_k127_411298_6	1487921.DP68_03390	4.921e-111	362.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,36FAP@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
HKD1_k127_411298_4	1487921.DP68_03395	1.119e-130	420.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
HKD1_k127_411298_1	1487921.DP68_18110	2.249e-209	656.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,36DC8@31979|Clostridiaceae	186801|Clostridia	E	PFAM Cys Met metabolism	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11995	Cys_Met_Meta_PP
HKD1_k127_411298_12	272563.CD630_35980	1.025e-11	65.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,25SCH@186804|Peptostreptococcaceae	186801|Clostridia	T	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HKD1_k127_411298_13	1487921.DP68_03395	0.000703	42.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
HKD1_k127_411298_11	1487921.DP68_03395	4.239e-20	90.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
HKD1_k127_411298_2	1301100.HG529384_gene4112	1.525e-193	612.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,36EM7@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
HKD1_k127_411298_5	1391646.AVSU01000079_gene2881	2.721e-130	423.0	COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes	1239|Firmicutes	M	NlpC/P60 family	lytE	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PG_binding_1
HKD1_k127_411298_8	555088.DealDRAFT_1277	6.413e-41	154.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,24M30@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
HKD1_k127_411298_3	641107.CDLVIII_2082	1.561e-133	434.0	COG2247@1|root,COG2247@2|Bacteria,1V5IS@1239|Firmicutes,24CRJ@186801|Clostridia,36WC1@31979|Clostridiaceae	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,NEAT
HKD1_k127_411298_0	871963.Desdi_1163	0.0	1117.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HKD1_k127_411298_9	1298920.KI911353_gene3110	9.297e-37	146.0	28M3X@1|root,2ZAHZ@2|Bacteria,1VAMQ@1239|Firmicutes,24EZ1@186801|Clostridia,221XQ@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4164387_26	509191.AEDB02000028_gene2901	1.428e-09	59.0	2EFGV@1|root,3399G@2|Bacteria,1U5Y2@1239|Firmicutes,24WP5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4164387_28	1462527.CCDM010000002_gene685	8.39e-06	48.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4164387_4	1476973.JMMB01000007_gene496	5.579e-225	702.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,25QCT@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HKD1_k127_4164387_2	1476973.JMMB01000007_gene497	6.327e-273	841.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,25R8B@186804|Peptostreptococcaceae	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_4164387_6	1301100.HG529436_gene6564	7.974e-203	634.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,36DYX@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HKD1_k127_4164387_23	1476973.JMMB01000007_gene499	6.343e-100	327.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25RRM@186804|Peptostreptococcaceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
HKD1_k127_4164387_16	1476973.JMMB01000007_gene500	4.153e-124	401.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,25QDZ@186804|Peptostreptococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
HKD1_k127_4164387_20	1476973.JMMB01000007_gene501	6.822e-111	360.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,25R9B@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HKD1_k127_4164387_0	1476973.JMMB01000007_gene502	1.358e-300	925.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,25QXP@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
HKD1_k127_4164387_3	1476973.JMMB01000007_gene503	5.341e-268	829.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25QME@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
HKD1_k127_4164387_10	1476973.JMMB01000007_gene504	1.737e-172	544.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,25QMF@186804|Peptostreptococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
HKD1_k127_4164387_8	1476973.JMMB01000007_gene505	9.399e-195	610.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25R5H@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	cobD2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15770	Aminotran_1_2
HKD1_k127_4164387_11	1476973.JMMB01000007_gene506	2.042e-154	490.0	COG4542@1|root,COG4542@2|Bacteria,1TSJB@1239|Firmicutes,24I5S@186801|Clostridia,25R3Q@186804|Peptostreptococcaceae	186801|Clostridia	Q	GHMP kinases N terminal domain	pduX	-	2.7.1.177	ko:K16651	ko00860,map00860	-	R06531	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HKD1_k127_4164387_19	1476973.JMMB01000007_gene507	3.079e-111	361.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,25R69@186804|Peptostreptococcaceae	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
HKD1_k127_4164387_5	1476973.JMMB01000007_gene508	4.904e-223	694.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,25QCM@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
HKD1_k127_4164387_18	1476973.JMMB01000007_gene509	6.83e-112	362.0	COG2241@1|root,COG2241@2|Bacteria,1V832@1239|Firmicutes,24JES@186801|Clostridia,25QJX@186804|Peptostreptococcaceae	186801|Clostridia	H	Precorrin-6y C5,15-methyltransferase (Decarboxylating)	cbiE	-	2.1.1.132,2.1.1.289	ko:K00595,ko:K03399	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07775	RC00003,RC01279,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15725	TP_methylase
HKD1_k127_4164387_22	1476973.JMMB01000007_gene510	7.082e-105	342.0	COG2242@1|root,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,25RAJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Putative methyltransferase	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
HKD1_k127_4164387_21	1423815.BACR01000011_gene701	7.271e-108	354.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,4HBN5@91061|Bacilli,3F5NQ@33958|Lactobacillaceae	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD1_k127_4164387_9	1476973.JMMB01000007_gene512	8.918e-173	549.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,25QV0@186804|Peptostreptococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
HKD1_k127_4164387_13	1476973.JMMB01000007_gene513	2.193e-145	462.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,25QEW@186804|Peptostreptococcaceae	186801|Clostridia	H	precorrin-3B C17-methyltransferase	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD1_k127_4164387_15	1476973.JMMB01000007_gene514	1.345e-130	420.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,25QQ6@186804|Peptostreptococcaceae	186801|Clostridia	H	reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15690	CbiJ
HKD1_k127_4164387_12	1301100.HG529436_gene6547	5.375e-154	488.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,36DQD@31979|Clostridiaceae	186801|Clostridia	H	sirohydrochlorin cobaltochelatase	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
HKD1_k127_4164387_14	1476973.JMMB01000007_gene516	4.965e-140	446.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,25RC1@186804|Peptostreptococcaceae	186801|Clostridia	H	Precorrin-2 C(20)-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HKD1_k127_4164387_17	386415.NT01CX_0262	1.379e-117	385.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,36EJC@31979|Clostridiaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
HKD1_k127_4164387_1	1476973.JMMB01000007_gene518	5.865e-293	902.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,25QIP@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
HKD1_k127_4164387_7	1476973.JMMB01000007_gene519	3.065e-198	619.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,25QF1@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HKD1_k127_4164387_24	1476973.JMMB01000007_gene520	1.172e-95	315.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,25T8S@186804|Peptostreptococcaceae	186801|Clostridia	H	Putative NAD(P)-binding	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
HKD1_k127_4173404_15	1476973.JMMB01000005_gene3490	6.27e-19	87.0	COG5566@1|root,COG5566@2|Bacteria,1U6IB@1239|Firmicutes,24VJC@186801|Clostridia,25TYE@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_4173404_17	1292035.H476_1443	4.998e-11	64.0	COG0642@1|root,COG0642@2|Bacteria,1V7G1@1239|Firmicutes,25ER0@186801|Clostridia,25S8E@186804|Peptostreptococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HKD1_k127_4173404_2	1292035.H476_2851	2.082e-187	615.0	COG0577@1|root,COG0577@2|Bacteria,1TX8D@1239|Firmicutes,25M7P@186801|Clostridia,25TJM@186804|Peptostreptococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
HKD1_k127_4173404_19	1347392.CCEZ01000016_gene2972	5.069e-06	52.0	COG1404@1|root,COG1404@2|Bacteria,1VNFX@1239|Firmicutes,25C1P@186801|Clostridia	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4173404_4	1476973.JMMB01000007_gene1414	3.936e-110	360.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25S4W@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4173404_10	1321778.HMPREF1982_02943	1.068e-61	215.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,24K11@186801|Clostridia,26B8Y@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_4173404_7	1301100.HG529244_gene2322	5.703e-86	286.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD1_k127_4173404_6	290402.Cbei_0389	9.677e-88	291.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	gpxA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
HKD1_k127_4173404_16	1301100.HG529348_gene4316	3.885e-15	76.0	29EXA@1|root,301V3@2|Bacteria,1UTZH@1239|Firmicutes,254Z8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4173404_5	702450.CUW_1925	1.527e-106	351.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes	1239|Firmicutes	S	COG NOG17660 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
HKD1_k127_4173404_9	1292035.H476_1568	1.004e-65	228.0	2AMQF@1|root,31CKN@2|Bacteria,1TTTK@1239|Firmicutes,257XE@186801|Clostridia,25UCQ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
HKD1_k127_4173404_13	1391646.AVSU01000028_gene2601	3.684e-54	193.0	COG1846@1|root,COG1846@2|Bacteria,1V73Z@1239|Firmicutes,25DW3@186801|Clostridia	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
HKD1_k127_4173404_8	1476973.JMMB01000007_gene3012	1.653e-79	267.0	COG1846@1|root,COG1846@2|Bacteria,1VEFZ@1239|Firmicutes,24MSB@186801|Clostridia,25TFF@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_4173404_0	1476973.JMMB01000007_gene3011	3.816e-232	725.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25SH6@186804|Peptostreptococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_4173404_3	941824.TCEL_01635	1.239e-173	551.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,36EHG@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HKD1_k127_4173404_14	983548.Krodi_1194	1.275e-44	180.0	28NP5@1|root,2ZBP5@2|Bacteria,4NFTH@976|Bacteroidetes,1HYRG@117743|Flavobacteriia,37DGS@326319|Dokdonia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	O-ag_pol_Wzy
HKD1_k127_4173404_12	1434325.AZQN01000003_gene2590	5.247e-55	208.0	COG0438@1|root,COG0438@2|Bacteria,4NIP2@976|Bacteroidetes,47MWD@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HKD1_k127_4173404_1	1292035.H476_2147	1.379e-195	614.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,25R62@186804|Peptostreptococcaceae	186801|Clostridia	G	UDP-N-acetylglucosamine 2-epimerase	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HKD1_k127_4173404_11	1476973.JMMB01000007_gene299	5.739e-57	200.0	COG1950@1|root,COG1950@2|Bacteria,1VAPZ@1239|Firmicutes,24JZV@186801|Clostridia,25TKP@186804|Peptostreptococcaceae	186801|Clostridia	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2
HKD1_k127_4225577_44	1476973.JMMB01000007_gene1908	1.273e-63	219.0	COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,25SJF@186804|Peptostreptococcaceae	186801|Clostridia	C	alcohol dehydrogenase	kdd	-	1.4.1.11	ko:K18012	ko00310,map00310	-	R03349	RC00888	ko00000,ko00001,ko01000	-	-	-	ADH_zinc_N
HKD1_k127_4225577_4	1301100.HG529329_gene4453	1.517e-254	786.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,36E9A@31979|Clostridiaceae	186801|Clostridia	E	lysine 2,3-aminomutase YodO family protein	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
HKD1_k127_4225577_14	1476973.JMMB01000007_gene1906	3.068e-163	519.0	2C3VR@1|root,2Z9AE@2|Bacteria,1UZNB@1239|Firmicutes,24D9F@186801|Clostridia,25S9W@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4225577_6	1408823.AXUS01000004_gene160	1.032e-199	633.0	COG1193@1|root,COG1193@2|Bacteria,1TSBW@1239|Firmicutes,24814@186801|Clostridia,25S2Y@186804|Peptostreptococcaceae	186801|Clostridia	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
HKD1_k127_4225577_2	1476973.JMMB01000007_gene1904	1.44e-321	987.0	COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,25SQF@186804|Peptostreptococcaceae	186801|Clostridia	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
HKD1_k127_4225577_19	1301100.HG529329_gene4449	1.289e-149	475.0	COG5012@1|root,COG5012@2|Bacteria,1UJB2@1239|Firmicutes,25F0A@186801|Clostridia,36EPZ@31979|Clostridiaceae	186801|Clostridia	S	Dimerisation domain of d-ornithine 4,5-aminomutase	-	-	5.4.3.3	ko:K18011	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	B12-binding,OAM_dimer
HKD1_k127_4225577_3	1476973.JMMB01000007_gene1902	1.253e-262	814.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25S6H@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HKD1_k127_4225577_21	1476973.JMMB01000007_gene1893	3.942e-140	449.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25T0J@186804|Peptostreptococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HKD1_k127_4225577_31	1151292.QEW_2356	1.914e-94	316.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25SBI@186804|Peptostreptococcaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD1_k127_4225577_59	1304880.JAGB01000002_gene2251	6.941e-20	95.0	COG2856@1|root,COG2856@2|Bacteria,1VEWS@1239|Firmicutes,24R47@186801|Clostridia	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HKD1_k127_4225577_66	1301100.HG529329_gene4472	3.652e-08	55.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,24UDD@186801|Clostridia,36N2M@31979|Clostridiaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_4225577_51	1476973.JMMB01000007_gene1873	2.9e-31	123.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JCT@186801|Clostridia,25RZF@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_4225577_34	1410653.JHVC01000007_gene490	1.133e-86	291.0	COG1396@1|root,COG1396@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,36GWJ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain protein	ydcN	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
HKD1_k127_4225577_22	1410653.JHVC01000007_gene489	2.496e-133	429.0	COG0189@1|root,COG0189@2|Bacteria,1VRHM@1239|Firmicutes,24Y0X@186801|Clostridia	186801|Clostridia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4225577_20	1476973.JMMB01000007_gene1983	3.054e-144	460.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,25NIT@186801|Clostridia,25T4Q@186804|Peptostreptococcaceae	186801|Clostridia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_4225577_42	1292035.H476_1799	4.052e-67	233.0	COG1670@1|root,COG1670@2|Bacteria,1V1VS@1239|Firmicutes,24HZU@186801|Clostridia	186801|Clostridia	J	GNAT family	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
HKD1_k127_4225577_33	1292035.H476_0573	5.071e-88	294.0	COG3275@1|root,COG3275@2|Bacteria,1V6MZ@1239|Firmicutes,24JJT@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF-ribofla_trS,ECF_trnsprt
HKD1_k127_4225577_36	1408823.AXUS01000026_gene1546	1.377e-81	275.0	COG5418@1|root,COG5418@2|Bacteria,1VA4H@1239|Firmicutes,24IR1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
HKD1_k127_4225577_67	1301100.HG529329_gene4469	1.626e-07	53.0	COG5566@1|root,COG5566@2|Bacteria,1VHWQ@1239|Firmicutes,24TPM@186801|Clostridia	186801|Clostridia	S	Mor transcription activator	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_4225577_40	1391646.AVSU01000091_gene478	1.471e-69	237.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,25TC9@186804|Peptostreptococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
HKD1_k127_4225577_30	926561.KB900619_gene2441	2.547e-106	360.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,3WB2V@53433|Halanaerobiales	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_4225577_60	1541959.KQ51_01654	1.148e-19	92.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
HKD1_k127_4225577_68	323850.Shew_0933	4.037e-07	55.0	COG0500@1|root,COG2226@2|Bacteria,1PF9T@1224|Proteobacteria,1T9PG@1236|Gammaproteobacteria,2QDI5@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
HKD1_k127_4225577_1	1476973.JMMB01000007_gene1865	0.0	1064.0	COG0488@1|root,COG0488@2|Bacteria,1TSB8@1239|Firmicutes,248XT@186801|Clostridia,25QK3@186804|Peptostreptococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HKD1_k127_4225577_38	1301100.HG529272_gene1715	2.305e-77	262.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,36DKS@31979|Clostridiaceae	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
HKD1_k127_4225577_41	1292035.H476_1312	3.432e-68	235.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia	186801|Clostridia	L	YqaJ viral recombinase family	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
HKD1_k127_4225577_46	1476973.JMMB01000007_gene1881	2.291e-45	179.0	COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,24IDX@186801|Clostridia,25T25@186804|Peptostreptococcaceae	186801|Clostridia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD1_k127_4225577_28	1476973.JMMB01000007_gene1880	9.547e-113	376.0	COG1484@1|root,COG1484@2|Bacteria,1V48P@1239|Firmicutes,24B2B@186801|Clostridia,25RRF@186804|Peptostreptococcaceae	186801|Clostridia	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD1_k127_4225577_53	1476973.JMMB01000007_gene1873	7.501e-31	122.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JCT@186801|Clostridia,25RZF@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_4225577_56	1476973.JMMB01000007_gene1872	9.823e-27	110.0	2A0AM@1|root,30NE1@2|Bacteria,1UF9X@1239|Firmicutes,252EI@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_4225577_62	1476973.JMMB01000007_gene1522	3.656e-14	73.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,25SX5@186804|Peptostreptococcaceae	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
HKD1_k127_4225577_25	1476973.JMMB01000007_gene1522	5.311e-126	408.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,25SX5@186804|Peptostreptococcaceae	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
HKD1_k127_4225577_69	1408823.AXUS01000001_gene772	7.225e-06	49.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25QTJ@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HKD1_k127_4225577_54	768704.Desmer_1410	3.659e-28	114.0	2EH55@1|root,33AX2@2|Bacteria,1VMSR@1239|Firmicutes,254HE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4225577_45	1408823.AXUS01000046_gene2913	1.401e-63	219.0	2BI2V@1|root,32C7W@2|Bacteria,1UGBK@1239|Firmicutes,24NXY@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3796
HKD1_k127_4225577_52	1391646.AVSU01000102_gene609	3.682e-31	123.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QJ1@186801|Clostridia,25U03@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD1_k127_4225577_49	1301100.HG529321_gene6077	2.303e-38	143.0	2EDTM@1|root,337NX@2|Bacteria,1VJSV@1239|Firmicutes,24ST1@186801|Clostridia,36MIR@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
HKD1_k127_4225577_39	349161.Dred_0452	3.363e-72	248.0	COG0655@1|root,COG0655@2|Bacteria,1TSPU@1239|Firmicutes,24AIV@186801|Clostridia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_4225577_57	272563.CD630_19310	6.194e-22	97.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25RMC@186804|Peptostreptococcaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HKD1_k127_4225577_55	1469607.KK073769_gene5872	1.068e-27	113.0	COG0346@1|root,COG0346@2|Bacteria,1G5QD@1117|Cyanobacteria,1HNHQ@1161|Nostocales	1117|Cyanobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
HKD1_k127_4225577_64	195103.CPF_0992	4.838e-12	70.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia,36FME@31979|Clostridiaceae	186801|Clostridia	V	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
HKD1_k127_4225577_50	457412.RSAG_01667	6.008e-32	128.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HKD1_k127_4225577_48	33035.JPJF01000037_gene2953	3.589e-39	160.0	COG2508@1|root,COG2508@2|Bacteria,1VIT3@1239|Firmicutes,24JXW@186801|Clostridia,3Y0T9@572511|Blautia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HKD1_k127_4225577_23	768710.DesyoDRAFT_3428	1.006e-132	427.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,263TW@186807|Peptococcaceae	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HKD1_k127_4225577_5	445973.CLOBAR_01206	9.749e-200	631.0	COG2211@1|root,COG2211@2|Bacteria,1V01M@1239|Firmicutes,24AXH@186801|Clostridia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HKD1_k127_4225577_16	445973.CLOBAR_01205	9.394e-158	504.0	COG0407@1|root,COG0407@2|Bacteria,1V5ND@1239|Firmicutes,24IEP@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
HKD1_k127_4225577_32	445973.CLOBAR_01207	5.911e-91	304.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25SDM@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	mtbC	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
HKD1_k127_4225577_13	33035.JPJF01000037_gene2956	1.697e-183	591.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HKD1_k127_4225577_43	33035.JPJF01000037_gene2955	2.377e-66	230.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia,3Y1BP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HKD1_k127_4225577_18	1340434.AXVA01000023_gene3374	5.072e-151	486.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus	91061|Bacilli	S	amidohydrolase	hipO3	-	-	ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_4225577_0	1301100.HG529430_gene1929	0.0	1077.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,36DDU@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
HKD1_k127_4225577_35	1301100.HG529260_gene6177	1.941e-82	280.0	COG0664@1|root,COG0664@2|Bacteria,1V8B2@1239|Firmicutes,25CK8@186801|Clostridia,36WXP@31979|Clostridiaceae	186801|Clostridia	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_4225577_12	1391646.AVSU01000007_gene152	1.875e-186	586.0	COG1143@1|root,COG1143@2|Bacteria,1UJ43@1239|Firmicutes,25EVE@186801|Clostridia,25R4J@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
HKD1_k127_4225577_17	1151292.QEW_2762	5.605e-156	493.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,25R4I@186804|Peptostreptococcaceae	186801|Clostridia	C	Oxidoreductase NAD-binding domain	asrB	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
HKD1_k127_4225577_9	1301100.HG529261_gene683	1.885e-195	611.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,36F1M@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	asrC	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_10,Fer4_21,Fer4_4,Fer4_6,NIR_SIR,NIR_SIR_ferr
HKD1_k127_4225577_24	1391646.AVSU01000007_gene149	5.359e-127	410.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,25R0D@186804|Peptostreptococcaceae	186801|Clostridia	P	Formate/nitrite transporter	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
HKD1_k127_4225577_47	1173028.ANKO01000014_gene1070	6.477e-40	166.0	COG2931@1|root,COG2931@2|Bacteria,1GFGD@1117|Cyanobacteria	1117|Cyanobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4225577_63	1280686.AUKE01000009_gene875	3.315e-12	79.0	COG2273@1|root,COG5498@1|root,COG2273@2|Bacteria,COG5498@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,4C1XG@830|Butyrivibrio	186801|Clostridia	G	Beta/gamma crystallins	bglA3	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Glyco_hydro_16,RicinB_lectin_2
HKD1_k127_4225577_37	1121335.Clst_0825	1.383e-81	278.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
HKD1_k127_4225577_7	1410653.JHVC01000036_gene3607	4.143e-198	621.0	COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,248E0@186801|Clostridia,36DXQ@31979|Clostridiaceae	186801|Clostridia	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
HKD1_k127_4225577_26	546269.HMPREF0389_01354	6.855e-118	383.0	COG1834@1|root,COG1834@2|Bacteria,1TRPV@1239|Firmicutes,24AKW@186801|Clostridia	186801|Clostridia	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
HKD1_k127_4225577_10	1123009.AUID01000010_gene544	1.164e-191	609.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,26A0G@186813|unclassified Clostridiales	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HKD1_k127_4225577_65	1301100.HG529329_gene4472	2.985e-09	57.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,24UDD@186801|Clostridia,36N2M@31979|Clostridiaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_4225577_15	1301100.HG529285_gene7055	3.069e-158	500.0	2E1UT@1|root,32X46@2|Bacteria,1VIFK@1239|Firmicutes,24DCT@186801|Clostridia,36DU0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4225577_61	1301100.HG529311_gene415	1.908e-19	89.0	2DZP5@1|root,32VF7@2|Bacteria,1VC6C@1239|Firmicutes,24RSJ@186801|Clostridia,36N23@31979|Clostridiaceae	186801|Clostridia	S	PFAM small acid-soluble spore protein alpha	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD1_k127_4225577_11	272563.CD630_01990	1.497e-189	602.0	COG0737@1|root,COG0737@2|Bacteria,1VTIP@1239|Firmicutes	1239|Firmicutes	F	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_4225577_8	272563.CD630_01990	4.878e-196	621.0	COG0737@1|root,COG0737@2|Bacteria,1VTIP@1239|Firmicutes	1239|Firmicutes	F	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HKD1_k127_4225577_29	1391646.AVSU01000131_gene2676	4.898e-110	359.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25SJA@186804|Peptostreptococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_4225577_27	1292035.H476_2463	1.357e-117	387.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia,25S94@186804|Peptostreptococcaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HKD1_k127_4333529_19	1151292.QEW_3777	2.089e-116	380.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,25SWR@186804|Peptostreptococcaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HKD1_k127_4333529_6	1476973.JMMB01000007_gene2925	1.484e-213	670.0	COG3860@1|root,COG3860@2|Bacteria,1VH55@1239|Firmicutes,24SY9@186801|Clostridia,25UJT@186804|Peptostreptococcaceae	186801|Clostridia	S	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4333529_2	1391646.AVSU01000081_gene2907	1.757e-288	890.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HKD1_k127_4333529_7	1476973.JMMB01000007_gene1730	3.717e-211	664.0	COG0258@1|root,COG0258@2|Bacteria,1UYXU@1239|Firmicutes,248E2@186801|Clostridia,25SUE@186804|Peptostreptococcaceae	186801|Clostridia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
HKD1_k127_4333529_30	332101.JIBU02000004_gene207	1.121e-22	98.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD1_k127_4333529_15	332101.JIBU02000004_gene205	4.26e-144	465.0	COG1454@1|root,COG1454@2|Bacteria,1TQMF@1239|Firmicutes,24828@186801|Clostridia,36F1E@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	4hbD	-	1.1.1.61	ko:K18120	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HKD1_k127_4333529_27	1391646.AVSU01000042_gene1401	2.206e-69	239.0	COG1633@1|root,COG1633@2|Bacteria,1V72Y@1239|Firmicutes,24JY4@186801|Clostridia,25TFA@186804|Peptostreptococcaceae	186801|Clostridia	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F,Rubrerythrin
HKD1_k127_4333529_23	1476973.JMMB01000007_gene1729	5.234e-100	329.0	COG2102@1|root,COG2102@2|Bacteria,1UAKZ@1239|Firmicutes,24C6P@186801|Clostridia,25RF6@186804|Peptostreptococcaceae	186801|Clostridia	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
HKD1_k127_4333529_17	1292035.H476_0738	3.439e-122	396.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,25B89@186801|Clostridia,25R51@186804|Peptostreptococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD1_k127_4333529_10	1476973.JMMB01000007_gene1727	6.463e-188	590.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,25R88@186804|Peptostreptococcaceae	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HKD1_k127_4333529_5	536227.CcarbDRAFT_3874	5.033e-233	728.0	COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,24BI4@186801|Clostridia,36FG1@31979|Clostridiaceae	186801|Clostridia	P	amino acid peptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	PTR2
HKD1_k127_4333529_33	332101.JIBU02000050_gene3455	9.04e-08	54.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36EQ0@31979|Clostridiaceae	186801|Clostridia	E	peptidase M24	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
HKD1_k127_4333529_1	1292035.H476_3409	0.0	1018.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,25S0Z@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
HKD1_k127_4333529_12	1476973.JMMB01000007_gene1726	1.436e-174	553.0	29VN7@1|root,30H5F@2|Bacteria,1UH5C@1239|Firmicutes,24XYN@186801|Clostridia,25SJN@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4333529_26	500633.CLOHIR_00452	1.075e-94	316.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,25SAI@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HKD1_k127_4333529_9	1476973.JMMB01000007_gene1724	3.308e-189	594.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,25R75@186804|Peptostreptococcaceae	186801|Clostridia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
HKD1_k127_4333529_16	1476973.JMMB01000007_gene1723	5.034e-133	426.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,25S33@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HKD1_k127_4333529_32	1304880.JAGB01000001_gene810	1.03e-08	60.0	COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,24NBA@186801|Clostridia	186801|Clostridia	S	TIGRFAM Protein of	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
HKD1_k127_4333529_24	1301100.HG529333_gene4589	1.148e-95	317.0	COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,24HCG@186801|Clostridia,36IWP@31979|Clostridiaceae	186801|Clostridia	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_4333529_4	1301100.HG529333_gene4591	4.773e-261	815.0	COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,36E1T@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD_5,PAS,PAS_4,PAS_9
HKD1_k127_4333529_3	1476973.JMMB01000007_gene1719	3.086e-287	885.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,25R5Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HKD1_k127_4333529_21	1476973.JMMB01000007_gene1718	8.359e-103	340.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,24H1Q@186801|Clostridia,25R2F@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD1_k127_4333529_29	1476973.JMMB01000007_gene1717	1.455e-48	176.0	29UDX@1|root,30FQK@2|Bacteria,1UEFE@1239|Firmicutes,25JC8@186801|Clostridia,25RXD@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4363)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4363
HKD1_k127_4333529_8	573061.Clocel_1144	2.357e-196	631.0	arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,2485U@186801|Clostridia,36EH0@31979|Clostridiaceae	186801|Clostridia	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062	-	-	-	-	-	-	-	-	-	-	Cthe_2159
HKD1_k127_4333529_20	1301100.HG529247_gene2387	2.472e-114	373.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,36G61@31979|Clostridiaceae	186801|Clostridia	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HKD1_k127_4333529_28	1301100.HG529247_gene2386	2.751e-69	238.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,36JKF@31979|Clostridiaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HKD1_k127_4333529_0	445973.CLOBAR_00934	0.0	1228.0	COG0574@1|root,COG0574@2|Bacteria,1TW0W@1239|Firmicutes,248VM@186801|Clostridia	186801|Clostridia	G	Pyruvate phosphate dikinase, PEP pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
HKD1_k127_4333529_11	1391646.AVSU01000147_gene3315	4.206e-184	580.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,248J3@186801|Clostridia	186801|Clostridia	P	calcium proton exchanger	cax	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
HKD1_k127_4333529_18	1151292.QEW_2039	1.321e-121	402.0	COG2271@1|root,COG2271@2|Bacteria,1UYKI@1239|Firmicutes,24C1B@186801|Clostridia	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_4333529_25	1301100.HG529238_gene7231	6.603e-95	312.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36I5H@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HKD1_k127_4333529_31	1391646.AVSU01000061_gene1044	3.412e-10	61.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,25SNS@186804|Peptostreptococcaceae	186801|Clostridia	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
HKD1_k127_4333529_14	1476973.JMMB01000007_gene2459	2.536e-148	478.0	COG1277@1|root,COG1277@2|Bacteria,1TURZ@1239|Firmicutes,24HKH@186801|Clostridia,25T5V@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HKD1_k127_4333529_13	1476973.JMMB01000007_gene2461	1.306e-154	491.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25SJV@186804|Peptostreptococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD1_k127_4333529_22	1476973.JMMB01000007_gene2462	2.325e-101	336.0	2E20S@1|root,32X8S@2|Bacteria,1VDSP@1239|Firmicutes,25P01@186801|Clostridia,25TCJ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4591991_1	1292035.H476_1152	8.969e-265	822.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25QF5@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_4591991_2	1476973.JMMB01000007_gene2475	6.889e-94	311.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,24IBK@186801|Clostridia,25TGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD1_k127_4591991_0	1391646.AVSU01000043_gene1419	0.0	1374.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25QF5@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_4591991_3	272563.CD630_22460	4.869e-29	119.0	COG1404@1|root,COG1404@2|Bacteria,1VRK5@1239|Firmicutes,249M4@186801|Clostridia,25S2A@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_4776192_7	1476973.JMMB01000007_gene2708	5.528e-12	68.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,25RI8@186804|Peptostreptococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HKD1_k127_4776192_3	1476973.JMMB01000007_gene2709	2.359e-219	687.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25QZ0@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HKD1_k127_4776192_8	1301100.HG529368_gene1327	1.487e-08	59.0	2CG49@1|root,32Y3Y@2|Bacteria,1VPBS@1239|Firmicutes,24RGW@186801|Clostridia,36N5U@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4776192_0	1476973.JMMB01000007_gene2710	0.0	1049.0	COG1236@1|root,COG1236@2|Bacteria,1V3Z5@1239|Firmicutes	1239|Firmicutes	J	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HKD1_k127_4776192_2	1476973.JMMB01000007_gene2711	2.723e-300	926.0	2EDRH@1|root,337M2@2|Bacteria,1V7V6@1239|Firmicutes,24JHI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4776192_1	1476973.JMMB01000007_gene2712	0.0	1032.0	COG0443@1|root,COG0443@2|Bacteria,1V0E7@1239|Firmicutes,24CUH@186801|Clostridia	186801|Clostridia	O	heat shock protein 70	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HKD1_k127_4776192_4	1476973.JMMB01000007_gene2713	5.709e-174	553.0	2C723@1|root,2ZXH2@2|Bacteria,1W34A@1239|Firmicutes,24TGJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4776192_5	1476973.JMMB01000007_gene2714	2.444e-173	545.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,25QFZ@186804|Peptostreptococcaceae	186801|Clostridia	E	Serine dehydratase alpha chain	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
HKD1_k127_4776192_6	1476973.JMMB01000007_gene2715	1.69e-128	412.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,25S17@186804|Peptostreptococcaceae	186801|Clostridia	E	Serine dehydratase beta chain	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
HKD1_k127_4784495_3	272563.CD630_28330	9.277e-212	665.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD1_k127_4784495_12	1301100.HG529303_gene3116	3.2e-90	303.0	COG4193@1|root,COG4193@2|Bacteria,1VGHY@1239|Firmicutes,24RC6@186801|Clostridia,36TWK@31979|Clostridiaceae	186801|Clostridia	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
HKD1_k127_4784495_17	1476973.JMMB01000007_gene1829	2e-45	167.0	COG1342@1|root,COG1342@2|Bacteria,1V7UV@1239|Firmicutes,24D5E@186801|Clostridia,25UMH@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function  DUF134	-	-	-	ko:K06933	-	-	-	-	ko00000	-	-	-	DUF134
HKD1_k127_4784495_16	1476973.JMMB01000007_gene1828	1.813e-45	167.0	2BT0T@1|root,32N4X@2|Bacteria,1UTSD@1239|Firmicutes,2544G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4784495_4	1476973.JMMB01000007_gene1827	7.568e-194	610.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
HKD1_k127_4784495_10	1476973.JMMB01000007_gene1826	3.14e-136	436.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,25QKH@186804|Peptostreptococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD1_k127_4784495_9	1476973.JMMB01000007_gene1825	5.29e-137	437.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,25SMV@186804|Peptostreptococcaceae	186801|Clostridia	J	S4 RNA-binding domain	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_4784495_6	1476973.JMMB01000007_gene1824	3.2e-175	557.0	COG3004@1|root,COG3004@2|Bacteria,1TS30@1239|Firmicutes,24AB3@186801|Clostridia,25SVU@186804|Peptostreptococcaceae	186801|Clostridia	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
HKD1_k127_4784495_2	1476973.JMMB01000007_gene1823	1.506e-217	684.0	COG1196@1|root,COG1196@2|Bacteria,1UXZK@1239|Firmicutes,24VIN@186801|Clostridia,25SPE@186804|Peptostreptococcaceae	186801|Clostridia	D	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
HKD1_k127_4784495_13	1408823.AXUS01000012_gene349	3.23e-88	295.0	COG2885@1|root,COG2885@2|Bacteria,1V6HB@1239|Firmicutes,24ARV@186801|Clostridia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HKD1_k127_4784495_8	1476973.JMMB01000007_gene1820	3.622e-140	447.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,25SQ2@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_4784495_11	1476973.JMMB01000007_gene1819	8.96e-115	372.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25RMC@186804|Peptostreptococcaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HKD1_k127_4784495_1	1476973.JMMB01000007_gene1818	1.077e-218	682.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,25QEC@186804|Peptostreptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerS	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD1_k127_4784495_18	1476973.JMMB01000007_gene1817	5.035e-24	103.0	2BH18@1|root,32B1H@2|Bacteria,1UGYN@1239|Firmicutes,256BJ@186801|Clostridia,25UCP@186804|Peptostreptococcaceae	186801|Clostridia	S	Small acid-soluble spore protein H family	-	-	-	-	-	-	-	-	-	-	-	-	SspH
HKD1_k127_4784495_7	1476973.JMMB01000007_gene1816	3.336e-175	552.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,25R9Y@186804|Peptostreptococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HKD1_k127_4784495_5	1476973.JMMB01000007_gene1815	3.384e-176	553.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,25R26@186804|Peptostreptococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD1_k127_4784495_0	1476973.JMMB01000007_gene1814	2.191e-266	823.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,25QMZ@186804|Peptostreptococcaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, biotin carboxylase subunit	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HKD1_k127_4784495_15	1476973.JMMB01000007_gene1813	2.352e-66	229.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,25RWT@186804|Peptostreptococcaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HKD1_k127_4784495_14	1476973.JMMB01000007_gene1812	1.805e-66	234.0	2FC41@1|root,3217M@2|Bacteria,1UEFP@1239|Firmicutes,25296@186801|Clostridia,25RYH@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4864916_3	500633.CLOHIR_01607	6.202e-113	367.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25QF6@186804|Peptostreptococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA1	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HKD1_k127_4864916_0	1476973.JMMB01000007_gene122	8.258e-150	476.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,25QTH@186804|Peptostreptococcaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HKD1_k127_4864916_1	1476973.JMMB01000007_gene121	1.56e-149	474.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,25R8Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD1_k127_4864916_4	1301100.HG529435_gene6503	1.178e-84	281.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,36HZ3@31979|Clostridiaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HKD1_k127_4864916_5	1476973.JMMB01000007_gene119	3.802e-74	250.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25RE4@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HKD1_k127_4864916_2	1476973.JMMB01000007_gene118	6.731e-128	412.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,25R58@186804|Peptostreptococcaceae	186801|Clostridia	M	Ami_3	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD1_k127_4981265_23	1476973.JMMB01000007_gene1707	1.013e-46	177.0	29USE@1|root,30G4I@2|Bacteria,1UF64@1239|Firmicutes,253ID@186801|Clostridia,25U94@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_2	1476973.JMMB01000007_gene1706	1.297e-239	741.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,25QWH@186804|Peptostreptococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HKD1_k127_4981265_7	1476973.JMMB01000007_gene1705	5.695e-153	486.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25SYK@186804|Peptostreptococcaceae	186801|Clostridia	S	Queuosine biosynthesis protein QueC	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
HKD1_k127_4981265_26	1476973.JMMB01000007_gene1704	1.228e-29	119.0	28XYC@1|root,2ZJU9@2|Bacteria,1W4VF@1239|Firmicutes,25564@186801|Clostridia,25RYB@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_21	1476973.JMMB01000007_gene2047	7.586e-55	199.0	2BD7G@1|root,306I0@2|Bacteria,1UEUY@1239|Firmicutes,25JUG@186801|Clostridia,25THH@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
HKD1_k127_4981265_8	1476973.JMMB01000007_gene2048	6.799e-153	486.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,25SZZ@186804|Peptostreptococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4981265_19	1301100.HG529334_gene4408	2.654e-65	225.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,36JPA@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HKD1_k127_4981265_1	1301100.HG529334_gene4414	1.446e-267	826.0	2CFPC@1|root,31SN4@2|Bacteria,1V9AH@1239|Firmicutes,24YWG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_0	1476973.JMMB01000007_gene1695	0.0	2399.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25QYX@186804|Peptostreptococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
HKD1_k127_4981265_29	1476973.JMMB01000007_gene1693	3.518e-21	93.0	2AFI0@1|root,315IK@2|Bacteria,1UUJI@1239|Firmicutes,256YC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_3	1476973.JMMB01000007_gene1682	2.14e-215	672.0	COG3314@1|root,COG3314@2|Bacteria,1TQDB@1239|Firmicutes,249BP@186801|Clostridia,25SKT@186804|Peptostreptococcaceae	186801|Clostridia	S	Transporter gate domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_5	1301100.HG529335_gene4423	1.804e-204	638.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD1_k127_4981265_30	1476973.JMMB01000007_gene1679	8.756e-16	78.0	2BGVG@1|root,328QJ@2|Bacteria,1UUNR@1239|Firmicutes,2579U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_25	1476973.JMMB01000007_gene1678	5.137e-36	138.0	29TY6@1|root,30F73@2|Bacteria,1UDK3@1239|Firmicutes,253XS@186801|Clostridia,25UCM@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_18	1476973.JMMB01000007_gene1677	1.27e-67	234.0	29UPF@1|root,30G14@2|Bacteria,1UF0A@1239|Firmicutes,251ER@186801|Clostridia,25U30@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_27	1410674.JNKU01000001_gene256	5.081e-29	117.0	COG0546@1|root,COG2827@1|root,COG0546@2|Bacteria,COG2827@2|Bacteria,1V1FQ@1239|Firmicutes,4HDVJ@91061|Bacilli,3F60K@33958|Lactobacillaceae	91061|Bacilli	L	haloacid dehalogenase-like hydrolase	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD1_k127_4981265_16	1410653.JHVC01000024_gene1131	3.255e-97	321.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,36JI7@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
HKD1_k127_4981265_10	1151292.QEW_1969	3.987e-138	441.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,25SNM@186804|Peptostreptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD1_k127_4981265_17	1128398.Curi_c17540	2.737e-87	294.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,2692X@186813|unclassified Clostridiales	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HKD1_k127_4981265_14	1151292.QEW_1967	9.071e-106	345.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,25SVT@186804|Peptostreptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HKD1_k127_4981265_20	489653.NLA_7000	1.326e-60	214.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,2KQ53@206351|Neisseriales	206351|Neisseriales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HKD1_k127_4981265_11	1230342.CTM_21141	1.409e-134	436.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,36DDS@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_4981265_4	1410653.JHVC01000024_gene1137	8.282e-209	655.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,36EFR@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HKD1_k127_4981265_15	1151292.QEW_1964	1.127e-100	331.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,25T18@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
HKD1_k127_4981265_12	1151292.QEW_1963	3.251e-120	393.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,25SDG@186804|Peptostreptococcaceae	186801|Clostridia	E	Histidyl-tRNA synthetase	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HKD1_k127_4981265_28	1487921.DP68_12505	4.383e-28	117.0	29V8V@1|root,30GNU@2|Bacteria,1UGCJ@1239|Firmicutes,24P19@186801|Clostridia,36MIF@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_4981265_9	37659.JNLN01000001_gene287	1.988e-143	465.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,36ETV@31979|Clostridiaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_4981265_13	1487921.DP68_10015	2.786e-106	348.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_4981265_24	1121024.AUCD01000020_gene578	1.777e-39	158.0	COG0845@1|root,COG0845@2|Bacteria,1V158@1239|Firmicutes,4HG27@91061|Bacilli,27G6D@186828|Carnobacteriaceae	91061|Bacilli	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HKD1_k127_4981265_22	1321778.HMPREF1982_00101	1.333e-51	193.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,26BJD@186813|unclassified Clostridiales	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Big_2,Cu_amine_oxidN1,DUF5011,YkuD
HKD1_k127_4981265_31	748727.CLJU_c01940	2.37e-15	78.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,36KS5@31979|Clostridiaceae	186801|Clostridia	L	Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HKD1_k127_4981265_6	1292035.H476_0156	1.602e-168	532.0	COG1915@1|root,COG1915@2|Bacteria,1TT91@1239|Firmicutes,24A6C@186801|Clostridia,25SWN@186804|Peptostreptococcaceae	186801|Clostridia	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5008604_0	1301100.HG529430_gene1973	0.0	2036.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD1_k127_5008604_2	1301100.HG529430_gene1972	1.208e-231	728.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_5008604_1	1476973.JMMB01000007_gene2890	0.0	1772.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SBR@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
HKD1_k127_5104707_4	1476973.JMMB01000007_gene556	2.36e-219	686.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,25QMT@186804|Peptostreptococcaceae	186801|Clostridia	FJ	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HKD1_k127_5104707_13	1476973.JMMB01000007_gene555	9.906e-126	406.0	COG0648@1|root,COG0648@2|Bacteria,1UFG6@1239|Firmicutes,24FBC@186801|Clostridia,25RBT@186804|Peptostreptococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HKD1_k127_5104707_16	1476973.JMMB01000007_gene554	7.9e-98	321.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,25RGZ@186804|Peptostreptococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD1_k127_5104707_9	1476973.JMMB01000007_gene553	1.195e-151	481.0	arCOG00127@1|root,33TE0@2|Bacteria,1VQPB@1239|Firmicutes,25JM6@186801|Clostridia,25SWS@186804|Peptostreptococcaceae	186801|Clostridia	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5104707_15	1476973.JMMB01000007_gene552	2.08e-115	376.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,24D4U@186801|Clostridia,25RE7@186804|Peptostreptococcaceae	186801|Clostridia	S	Protease prsW family	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
HKD1_k127_5104707_1	1476973.JMMB01000007_gene551	1.481e-255	790.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25QWF@186804|Peptostreptococcaceae	186801|Clostridia	M	Putative peptidoglycan binding domain	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
HKD1_k127_5104707_3	1476973.JMMB01000007_gene550	2.37e-220	691.0	COG5513@1|root,COG5513@2|Bacteria,1V52X@1239|Firmicutes,25ER6@186801|Clostridia,25T2Z@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,DUF3298,DUF4163
HKD1_k127_5104707_26	290402.Cbei_4151	1.428e-21	94.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,36MNT@31979|Clostridiaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
HKD1_k127_5104707_19	509191.AEDB02000033_gene5119	4.653e-79	271.0	COG0288@1|root,COG0288@2|Bacteria,1V1YB@1239|Firmicutes,24GMG@186801|Clostridia,3WIN4@541000|Ruminococcaceae	186801|Clostridia	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD1_k127_5104707_24	1499689.CCNN01000007_gene2385	2.902e-45	164.0	COG1359@1|root,COG1359@2|Bacteria,1VDR6@1239|Firmicutes,25AXG@186801|Clostridia,36W67@31979|Clostridiaceae	186801|Clostridia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HKD1_k127_5104707_14	1410653.JHVC01000032_gene1027	2.119e-124	400.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,36E3H@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_5104707_6	1345695.CLSA_c25210	1.58e-159	508.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD1_k127_5104707_21	1410653.JHVC01000032_gene1029	1.004e-64	223.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,36JQ7@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD1_k127_5104707_0	1476973.JMMB01000007_gene549	1.613e-274	846.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25QXJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD1_k127_5104707_12	1301100.HG529409_gene194	4.637e-136	435.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,36ESJ@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_5104707_22	1476973.JMMB01000007_gene547	4.229e-62	214.0	COG1942@1|root,COG1942@2|Bacteria,1VA6U@1239|Firmicutes,24MXT@186801|Clostridia,25RDA@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
HKD1_k127_5104707_5	1476973.JMMB01000007_gene546	2.633e-178	559.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,25R5K@186804|Peptostreptococcaceae	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HKD1_k127_5104707_20	1476973.JMMB01000007_gene545	1.097e-77	262.0	2F1RD@1|root,33URH@2|Bacteria,1VV7T@1239|Firmicutes,250T6@186801|Clostridia,25RGW@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5104707_17	1476973.JMMB01000007_gene544	1.942e-97	320.0	COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,24MK8@186801|Clostridia,25RR6@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the 5'(3')-deoxyribonucleotidase family	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
HKD1_k127_5104707_18	1476973.JMMB01000007_gene543	3.124e-97	326.0	2F1QD@1|root,33UQK@2|Bacteria,1VUNT@1239|Firmicutes,24YEN@186801|Clostridia,25RUH@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5104707_10	1476973.JMMB01000007_gene542	4.848e-145	460.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,25R0P@186804|Peptostreptococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
HKD1_k127_5104707_7	1476973.JMMB01000007_gene541	5.669e-156	494.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25QGC@186804|Peptostreptococcaceae	186801|Clostridia	S	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HKD1_k127_5104707_8	1476973.JMMB01000007_gene540	8.66e-153	487.0	COG0491@1|root,COG0491@2|Bacteria,1TT3D@1239|Firmicutes,24BV1@186801|Clostridia,25QQM@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_5104707_11	1476973.JMMB01000007_gene539	2.286e-138	441.0	COG0727@1|root,COG0727@2|Bacteria,1VIET@1239|Firmicutes,24UUA@186801|Clostridia,25S95@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
HKD1_k127_5104707_25	1301100.HG529409_gene204	3.569e-41	152.0	2EUBX@1|root,33MU9@2|Bacteria,1VQ4S@1239|Firmicutes,24UHJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5104707_23	1476973.JMMB01000007_gene537	2.435e-54	192.0	2EBCU@1|root,335DI@2|Bacteria,1VENS@1239|Firmicutes,24T2K@186801|Clostridia,25TNR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5104707_2	1476973.JMMB01000007_gene536	4.308e-236	732.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25QMH@186804|Peptostreptococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
HKD1_k127_5134467_4	1235793.C809_03255	4.79e-08	60.0	2FI0M@1|root,349TJ@2|Bacteria,1VZP5@1239|Firmicutes,257B5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5134467_0	742740.HMPREF9474_02314	1.175e-64	229.0	2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5134467_3	665956.HMPREF1032_00636	9.545e-09	59.0	2EHGQ@1|root,33B8K@2|Bacteria,1VQCA@1239|Firmicutes,24WER@186801|Clostridia,3WQ9X@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5134467_1	742740.HMPREF9474_02312	2.806e-31	132.0	2B7V5@1|root,3211Y@2|Bacteria,1V7MK@1239|Firmicutes,24JA7@186801|Clostridia,222WR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5163871_4	1391646.AVSU01000016_gene3148	7.193e-164	522.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25QQN@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HKD1_k127_5163871_6	1151292.QEW_2805	9.287e-140	450.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25S46@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD1_k127_5163871_1	1151292.QEW_2806	2.317e-244	769.0	COG3711@1|root,COG4668@1|root,COG3711@2|Bacteria,COG4668@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,25RHJ@186804|Peptostreptococcaceae	186801|Clostridia	G	Mga helix-turn-helix domain	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
HKD1_k127_5163871_2	1301100.HG529333_gene4590	4.627e-243	756.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HKD1_k127_5163871_7	696281.Desru_2770	8.005e-138	446.0	COG0697@1|root,COG0697@2|Bacteria,1TPST@1239|Firmicutes,248K5@186801|Clostridia,2619B@186807|Peptococcaceae	186801|Clostridia	EG	DMT(Drug metabolite transporter) superfamily permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_5163871_12	1121324.CLIT_2c01530	1.899e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,1V4A7@1239|Firmicutes,24FJI@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_5163871_5	1292035.H476_0147	1.357e-141	471.0	COG1289@1|root,COG1289@2|Bacteria,1TQSC@1239|Firmicutes,247TY@186801|Clostridia	186801|Clostridia	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD1_k127_5163871_10	1033737.CAEV01000024_gene3516	2.136e-45	166.0	2BZQQ@1|root,33YTS@2|Bacteria,1VXSQ@1239|Firmicutes,24JBV@186801|Clostridia,36JRV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5163871_9	1408823.AXUS01000019_gene2227	3.177e-51	183.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,25UCA@186804|Peptostreptococcaceae	186801|Clostridia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_5163871_13	350688.Clos_1182	1.079e-16	83.0	2EM44@1|root,33ETM@2|Bacteria,1VN0P@1239|Firmicutes,24WH3@186801|Clostridia,36P5H@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5163871_3	1487921.DP68_10000	3.831e-223	698.0	COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,24BI4@186801|Clostridia,36FG1@31979|Clostridiaceae	186801|Clostridia	P	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
HKD1_k127_5163871_0	1120998.AUFC01000005_gene756	3.048e-252	796.0	COG0642@1|root,COG4936@1|root,COG2205@2|Bacteria,COG4936@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
HKD1_k127_5163871_8	195103.CPF_1243	1.783e-123	424.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
HKD1_k127_5163871_11	1122927.KB895416_gene3591	5.648e-30	120.0	COG2271@1|root,COG2271@2|Bacteria,1UZ2K@1239|Firmicutes,4HJES@91061|Bacilli	91061|Bacilli	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_5181999_15	1391646.AVSU01000045_gene1478	6.97e-86	286.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25QHU@186804|Peptostreptococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran,Rad17
HKD1_k127_5181999_12	1391646.AVSU01000045_gene1477	5.998e-106	348.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,25RA3@186804|Peptostreptococcaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD1_k127_5181999_8	1391646.AVSU01000045_gene1476	1.968e-114	374.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25REG@186804|Peptostreptococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD1_k127_5181999_7	1391646.AVSU01000045_gene1478	4.247e-129	415.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25QHU@186804|Peptostreptococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran,Rad17
HKD1_k127_5181999_11	1391646.AVSU01000045_gene1477	2.809e-107	351.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,25RA3@186804|Peptostreptococcaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HKD1_k127_5181999_9	1391646.AVSU01000045_gene1476	2.556e-114	374.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25REG@186804|Peptostreptococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HKD1_k127_5181999_14	1391646.AVSU01000045_gene1475	3.308e-91	301.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,25RCS@186804|Peptostreptococcaceae	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
HKD1_k127_5181999_13	1391646.AVSU01000045_gene1474	6.49e-98	324.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,25RBG@186804|Peptostreptococcaceae	186801|Clostridia	S	Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HKD1_k127_5181999_0	1476973.JMMB01000007_gene106	4.427e-289	890.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25QNQ@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
HKD1_k127_5181999_16	1301100.HG529431_gene1856	7.112e-77	259.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,36FGM@31979|Clostridiaceae	186801|Clostridia	K	AsnC family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HKD1_k127_5181999_10	1476973.JMMB01000007_gene108	6.442e-111	361.0	COG2844@1|root,COG2844@2|Bacteria,1VV9H@1239|Firmicutes,25EXR@186801|Clostridia,25TDC@186804|Peptostreptococcaceae	186801|Clostridia	O	HD domain	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,tRNA_NucTran2_2
HKD1_k127_5181999_4	1476973.JMMB01000007_gene109	2.167e-159	504.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,25QFD@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HKD1_k127_5181999_5	1476973.JMMB01000007_gene110	1.428e-156	494.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,25QWN@186804|Peptostreptococcaceae	186801|Clostridia	S	Methyltransferase domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
HKD1_k127_5181999_2	1476973.JMMB01000007_gene111	1.7e-180	566.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,25QP1@186804|Peptostreptococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
HKD1_k127_5181999_3	1301100.HG529432_gene1861	1.678e-173	547.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,36DG8@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HKD1_k127_5181999_6	1476973.JMMB01000007_gene113	2.047e-130	418.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,25J57@186801|Clostridia,25QYY@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
HKD1_k127_5181999_1	1476973.JMMB01000007_gene114	1.409e-255	794.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25QV5@186804|Peptostreptococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain protein	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HKD1_k127_5181999_18	1476973.JMMB01000007_gene115	1.481e-21	94.0	COG2155@1|root,COG2155@2|Bacteria,1UEFS@1239|Firmicutes,25JCK@186801|Clostridia,25RYK@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HKD1_k127_5181999_17	445973.CLOBAR_00769	1.067e-31	123.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5244272_27	1476973.JMMB01000007_gene656	2.971e-70	240.0	COG1051@1|root,COG1051@2|Bacteria,1V81X@1239|Firmicutes,24M8P@186801|Clostridia,25RE1@186804|Peptostreptococcaceae	186801|Clostridia	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_5244272_16	1301100.HG529403_gene6780	8.005e-116	376.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,36FC7@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein family UPF0029	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
HKD1_k127_5244272_32	1476973.JMMB01000007_gene658	9.736e-53	191.0	2999B@1|root,2ZWCI@2|Bacteria,1W2CR@1239|Firmicutes,252NM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5244272_31	1301100.HG529403_gene6778	3.232e-56	199.0	COG0730@1|root,COG0730@2|Bacteria,1VAFU@1239|Firmicutes,24MTI@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5244272_30	1476973.JMMB01000007_gene660	1.752e-58	204.0	COG0730@1|root,COG0730@2|Bacteria,1VAMI@1239|Firmicutes,24MXA@186801|Clostridia,25RM7@186804|Peptostreptococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5244272_14	1301100.HG529403_gene6775	3.664e-138	442.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
HKD1_k127_5244272_13	1476973.JMMB01000007_gene663	7.825e-140	446.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,25QC4@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HKD1_k127_5244272_36	445973.CLOBAR_01183	3.092e-34	134.0	29NRT@1|root,309PT@2|Bacteria,1U5GC@1239|Firmicutes,25JDY@186801|Clostridia,25TYR@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HKD1_k127_5244272_33	1301100.HG529402_gene6770	5.108e-43	160.0	2BE3N@1|root,2ZD2V@2|Bacteria,1UTR9@1239|Firmicutes,253ZX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5244272_21	1476973.JMMB01000007_gene666	1.289e-85	287.0	2B7SU@1|root,320Z7@2|Bacteria,1UEE9@1239|Firmicutes,25JAK@186801|Clostridia,25RQV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5244272_19	1476973.JMMB01000007_gene667	7.584e-99	323.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,25RA6@186804|Peptostreptococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HKD1_k127_5244272_17	1476973.JMMB01000007_gene668	1.48e-113	367.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,25RJE@186804|Peptostreptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HKD1_k127_5244272_9	1476973.JMMB01000007_gene669	1.299e-203	635.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25QWA@186804|Peptostreptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HKD1_k127_5244272_10	1476973.JMMB01000007_gene670	5.745e-202	631.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,25QXU@186804|Peptostreptococcaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HKD1_k127_5244272_26	1476973.JMMB01000007_gene671	9.229e-71	241.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,25JAT@186801|Clostridia,25RS6@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5244272_7	1476973.JMMB01000007_gene672	4.234e-244	755.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HKD1_k127_5244272_34	1476973.JMMB01000007_gene673	6.782e-42	155.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25RND@186804|Peptostreptococcaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HKD1_k127_5244272_29	1476973.JMMB01000007_gene675	2.372e-61	213.0	2DSAE@1|root,33F8G@2|Bacteria,1VKVA@1239|Firmicutes,25JAS@186801|Clostridia,25RRZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3792)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
HKD1_k127_5244272_38	1391646.AVSU01000029_gene2634	2.796e-22	96.0	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,25RXA@186804|Peptostreptococcaceae	186801|Clostridia	S	six-cysteine peptide	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
HKD1_k127_5244272_39	1476973.JMMB01000007_gene681	2.365e-09	59.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,25T9T@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_5244272_6	1476973.JMMB01000007_gene682	2.89e-255	794.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,25R0J@186804|Peptostreptococcaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_5244272_24	1476973.JMMB01000007_gene683	3.384e-74	252.0	COG2206@1|root,COG2206@2|Bacteria,1VKH8@1239|Firmicutes,25DNQ@186801|Clostridia	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_5244272_5	1476973.JMMB01000007_gene684	4.258e-281	866.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,25QV7@186804|Peptostreptococcaceae	186801|Clostridia	C	Six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
HKD1_k127_5244272_23	1301100.HG529402_gene6758	2.606e-83	280.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,36IWM@31979|Clostridiaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
HKD1_k127_5244272_3	1476973.JMMB01000007_gene686	1.98e-304	939.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,25QQ3@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
HKD1_k127_5244272_0	1476973.JMMB01000007_gene687	0.0	1404.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25QXQ@186804|Peptostreptococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
HKD1_k127_5244272_20	1301100.HG529402_gene6754	1.09e-98	323.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,36HZI@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HKD1_k127_5244272_1	1476973.JMMB01000007_gene689	0.0	1345.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,25QV9@186804|Peptostreptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
HKD1_k127_5244272_22	1476973.JMMB01000007_gene690	2.255e-84	280.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,25REI@186804|Peptostreptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HKD1_k127_5244272_18	1476973.JMMB01000007_gene691	1.341e-109	356.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,25RCT@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HKD1_k127_5244272_4	1476973.JMMB01000007_gene692	2.095e-289	892.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25QG9@186804|Peptostreptococcaceae	186801|Clostridia	H	coproporphyrinogen III oxidase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD1_k127_5244272_12	1294142.CINTURNW_1326	3.953e-151	488.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,36FA9@31979|Clostridiaceae	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD1_k127_5244272_2	1476973.JMMB01000007_gene694	0.0	1129.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25QPR@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
HKD1_k127_5244272_37	1476973.JMMB01000007_gene701	2.695e-31	124.0	29UQ0@1|root,30G1Q@2|Bacteria,1UF1M@1239|Firmicutes,253Q6@186801|Clostridia,25U7E@186804|Peptostreptococcaceae	186801|Clostridia	S	Small, acid-soluble spore proteins, alpha/beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD1_k127_5244272_35	1301100.HG529401_gene6794	1.253e-41	154.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,36MMZ@31979|Clostridiaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HKD1_k127_5244272_28	1476973.JMMB01000007_gene703	9.467e-65	224.0	COG3086@1|root,COG3086@2|Bacteria,1VEYP@1239|Firmicutes,24R8Z@186801|Clostridia,25RMJ@186804|Peptostreptococcaceae	186801|Clostridia	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
HKD1_k127_5244272_25	1476973.JMMB01000007_gene705	9.774e-74	250.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,25RNQ@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HKD1_k127_5244272_15	1476973.JMMB01000007_gene706	2.054e-131	423.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24BW5@186801|Clostridia,25UHU@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
HKD1_k127_5244272_8	272563.CD630_27260	1.353e-232	724.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,25QIA@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD1_k127_5244272_11	1301100.HG529400_gene6789	2.443e-201	635.0	COG1906@1|root,COG1906@2|Bacteria,1UHZ1@1239|Firmicutes,248VI@186801|Clostridia,36UMH@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_25	1476973.JMMB01000005_gene3469	7.675e-33	128.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JM4@186801|Clostridia,25TZ3@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_5373386_29	1476973.JMMB01000001_gene3353	5.058e-25	106.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,25JZH@186801|Clostridia,25U05@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_5373386_9	1220589.CD32_02200	4.48e-85	296.0	2BUKN@1|root,32PX6@2|Bacteria,1U26F@1239|Firmicutes,4HVHK@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
HKD1_k127_5373386_35	1443125.Z962_p0048	3.59e-13	71.0	2DSPI@1|root,33GXY@2|Bacteria,1VQCM@1239|Firmicutes,24VGS@186801|Clostridia,36T98@31979|Clostridiaceae	186801|Clostridia	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
HKD1_k127_5373386_34	272563.CD630_33400	1.388e-13	76.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25QZD@186804|Peptostreptococcaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
HKD1_k127_5373386_17	1499684.CCNP01000018_gene1789	7.633e-57	199.0	2E89A@1|root,32UHK@2|Bacteria,1VCWG@1239|Firmicutes,24PP4@186801|Clostridia,36MJD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_6	1292035.H476_0268	1.342e-105	346.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2,SH3_3,SPOR
HKD1_k127_5373386_32	1301100.HG529426_gene1995	1.077e-19	93.0	2BEE6@1|root,3285C@2|Bacteria,1UU2Q@1239|Firmicutes,2559T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_37	1304284.L21TH_2323	1.304e-08	59.0	29UMQ@1|root,30FZ8@2|Bacteria,1UEX1@1239|Firmicutes,25P4R@186801|Clostridia,36TYD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_7	1476973.JMMB01000003_gene60	3.912e-91	302.0	2DS28@1|root,33E72@2|Bacteria,1VBPU@1239|Firmicutes,24SNF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_5	545697.HMPREF0216_01659	6.948e-124	404.0	COG5464@1|root,COG5464@2|Bacteria,1V3AQ@1239|Firmicutes,24FYX@186801|Clostridia,36NHM@31979|Clostridiaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_28	1151292.QEW_0735	7.076e-26	113.0	29UR6@1|root,30G35@2|Bacteria,1UF3Z@1239|Firmicutes,24X3K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_10	702450.CUW_0403	1.791e-79	275.0	COG2378@1|root,COG2378@2|Bacteria,1TWXW@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
HKD1_k127_5373386_19	1345023.M467_10725	3.04e-49	196.0	COG0628@1|root,COG0628@2|Bacteria,1UZTM@1239|Firmicutes,4HT0R@91061|Bacilli	91061|Bacilli	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_4	1476973.JMMB01000005_gene3511	3.805e-146	464.0	COG1961@1|root,COG1961@2|Bacteria,1UEH2@1239|Firmicutes,25JE1@186801|Clostridia,25S4I@186804|Peptostreptococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
HKD1_k127_5373386_12	1391646.AVSU01000019_gene1322	1.141e-65	232.0	2DZ0W@1|root,34C2B@2|Bacteria,1VZKG@1239|Firmicutes,24QXF@186801|Clostridia,25RXX@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_13	1391646.AVSU01000019_gene1321	1.18e-64	221.0	COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,25N2P@186801|Clostridia,25TGE@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD1_k127_5373386_39	1280663.ATVR01000017_gene1159	2.056e-06	54.0	2BM7W@1|root,32FRK@2|Bacteria,1UF04@1239|Firmicutes,25K0B@186801|Clostridia,4C17T@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_36	1304284.L21TH_2323	2.065e-10	65.0	29UMQ@1|root,30FZ8@2|Bacteria,1UEX1@1239|Firmicutes,25P4R@186801|Clostridia,36TYD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_2	1476973.JMMB01000004_gene3396	2.619e-160	507.0	COG1192@1|root,COG1192@2|Bacteria,1UEGM@1239|Firmicutes,25JDI@186801|Clostridia,25S2G@186804|Peptostreptococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HKD1_k127_5373386_16	1476973.JMMB01000004_gene3397	1.218e-58	205.0	2BM3W@1|root,32FM7@2|Bacteria,1UEXY@1239|Firmicutes,25JXM@186801|Clostridia,25TT7@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_22	1410653.JHVC01000011_gene915	7.935e-39	146.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,36FX9@31979|Clostridiaceae	186801|Clostridia	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
HKD1_k127_5373386_30	1301100.HG529320_gene6100	3.599e-23	101.0	2C99Q@1|root,302JK@2|Bacteria,1UUHH@1239|Firmicutes,256SJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_14	500633.CLOHIR_00113	2.9e-63	218.0	COG3677@1|root,COG3677@2|Bacteria,1UYY4@1239|Firmicutes,248FF@186801|Clostridia,25S2T@186804|Peptostreptococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1,Zn_Tnp_IS1595
HKD1_k127_5373386_11	445335.CBN_2760	1.233e-70	242.0	COG4767@1|root,COG4767@2|Bacteria,1V7FP@1239|Firmicutes,24IQ9@186801|Clostridia	186801|Clostridia	V	VanZ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HKD1_k127_5373386_27	1476973.JMMB01000004_gene3397	1.145e-31	124.0	2BM3W@1|root,32FM7@2|Bacteria,1UEXY@1239|Firmicutes,25JXM@186801|Clostridia,25TT7@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_18	1391647.AVSV01000029_gene2015	4.045e-50	183.0	COG4219@1|root,COG4219@2|Bacteria,1V8ND@1239|Firmicutes,24QUK@186801|Clostridia,36NMC@31979|Clostridiaceae	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
HKD1_k127_5373386_0	1292035.H476_3056	6.856e-244	762.0	28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,24AWI@186801|Clostridia,25RER@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_3	1476973.JMMB01000004_gene3380	4.161e-148	471.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,25SA1@186804|Peptostreptococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5373386_21	1391646.AVSU01000061_gene1075	5.517e-43	162.0	2BKZ9@1|root,32FG0@2|Bacteria,1UEVE@1239|Firmicutes,25JUY@186801|Clostridia,25TIM@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_26	1391646.AVSU01000061_gene1076	1.268e-32	126.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QJ1@186801|Clostridia,25TYX@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD1_k127_5373386_8	768706.Desor_2320	1.372e-90	301.0	COG1335@1|root,COG1335@2|Bacteria,1V24R@1239|Firmicutes,24A32@186801|Clostridia,266EP@186807|Peptococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HKD1_k127_5373386_1	1476973.JMMB01000005_gene3459	4.518e-236	735.0	COG2522@1|root,COG2522@2|Bacteria,1V00D@1239|Firmicutes,24H1A@186801|Clostridia,25SJT@186804|Peptostreptococcaceae	186801|Clostridia	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_23	1476973.JMMB01000004_gene3415	1.547e-38	146.0	2BE00@1|root,327QK@2|Bacteria,1UTKY@1239|Firmicutes,253GW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5373386_20	1476973.JMMB01000007_gene1929	5.685e-46	166.0	COG5566@1|root,COG5566@2|Bacteria,1U6IB@1239|Firmicutes,24VJC@186801|Clostridia,25TYE@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_5400505_31	1476973.JMMB01000007_gene1287	9.283e-21	93.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,25RPX@186804|Peptostreptococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HKD1_k127_5400505_18	1476973.JMMB01000004_gene3418	6.913e-92	304.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,25SWU@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_5400505_26	1476973.JMMB01000004_gene3418	1.001e-48	176.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,25SWU@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_5400505_28	1301100.HG529400_gene6791	4.27e-42	160.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,36JMC@31979|Clostridiaceae	186801|Clostridia	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HKD1_k127_5400505_19	1301100.HG529400_gene6790	2.067e-91	308.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24BW5@186801|Clostridia,36QSU@31979|Clostridiaceae	186801|Clostridia	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
HKD1_k127_5400505_23	1476973.JMMB01000007_gene794	4.27e-66	227.0	COG0582@1|root,COG0582@2|Bacteria,1UIWX@1239|Firmicutes,25EZD@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HKD1_k127_5400505_34	220668.lp_1997	5.026e-14	72.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	int7	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HKD1_k127_5400505_29	1301100.HG529278_gene1539	6.944e-40	148.0	2FHHF@1|root,349BG@2|Bacteria,1W0RN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5400505_7	1151292.QEW_2637	6.373e-163	521.0	28HHD@1|root,2Z7T3@2|Bacteria,1TRKJ@1239|Firmicutes,24A0Y@186801|Clostridia,25RVI@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
HKD1_k127_5400505_1	1301100.HG529278_gene1531	0.0	1013.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
HKD1_k127_5400505_27	1476973.JMMB01000005_gene3479	3.554e-45	168.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,24BET@186801|Clostridia,25SBC@186804|Peptostreptococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_5400505_0	1211817.CCAT010000047_gene2532	0.0	3426.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia,36G18@31979|Clostridiaceae	186801|Clostridia	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
HKD1_k127_5400505_17	1391646.AVSU01000042_gene1406	8.596e-94	316.0	COG1361@1|root,COG1361@2|Bacteria,1VXRT@1239|Firmicutes,24QK2@186801|Clostridia	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5400505_22	1391646.AVSU01000042_gene1407	2.975e-66	229.0	28WQD@1|root,2ZIQ2@2|Bacteria,1W63R@1239|Firmicutes,24VM0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794
HKD1_k127_5400505_12	1301100.HG529429_gene1896	1.698e-125	405.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,36E4F@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
HKD1_k127_5400505_4	1415774.U728_3183	3.841e-169	538.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,36FD4@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HKD1_k127_5400505_16	536233.CLO_3088	1.158e-97	324.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia	186801|Clostridia	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HKD1_k127_5400505_5	1476973.JMMB01000007_gene1283	1.425e-166	531.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25QVB@186804|Peptostreptococcaceae	186801|Clostridia	S	AI-2E family transporter	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_5400505_3	1476973.JMMB01000007_gene1283	3.553e-195	614.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25QVB@186804|Peptostreptococcaceae	186801|Clostridia	S	AI-2E family transporter	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HKD1_k127_5400505_13	1476973.JMMB01000007_gene1282	4.553e-113	372.0	COG5164@1|root,COG5164@2|Bacteria	2|Bacteria	K	cell wall organization	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Collagen,Gram_pos_anchor,Laminin_G_3
HKD1_k127_5400505_14	1476973.JMMB01000007_gene1281	6.86e-107	349.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,25QJJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HKD1_k127_5400505_9	1476973.JMMB01000007_gene1280	6.776e-154	488.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,25R0Q@186804|Peptostreptococcaceae	186801|Clostridia	H	pfkB family carbohydrate kinase	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HKD1_k127_5400505_20	1476973.JMMB01000007_gene1279	1.408e-89	297.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25RE8@186804|Peptostreptococcaceae	186801|Clostridia	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HKD1_k127_5400505_6	1476973.JMMB01000007_gene1278	3.454e-163	516.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25QGM@186804|Peptostreptococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HKD1_k127_5400505_15	1476973.JMMB01000007_gene1277	4.866e-105	343.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,25RD7@186804|Peptostreptococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HKD1_k127_5400505_30	1151292.QEW_2211	4.243e-25	106.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25U6W@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
HKD1_k127_5400505_8	1476973.JMMB01000007_gene1276	5.661e-156	498.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GVR@186801|Clostridia,25QSR@186804|Peptostreptococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5400505_2	1476973.JMMB01000007_gene1275	5.086e-229	715.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2494M@186801|Clostridia,25SXK@186804|Peptostreptococcaceae	186801|Clostridia	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HKD1_k127_5400505_10	1476973.JMMB01000007_gene739	1.743e-135	434.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,25QKM@186804|Peptostreptococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	ywqE	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD1_k127_5400505_24	1151292.QEW_1365	6.287e-52	188.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25RHG@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
HKD1_k127_5400505_11	1292035.H476_0590	3.578e-134	434.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD1_k127_5400505_32	318464.IO99_07255	7.866e-15	78.0	2AF8J@1|root,3157Q@2|Bacteria,1UUEF@1239|Firmicutes,256IC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5400505_21	1408422.JHYF01000008_gene3573	7.865e-79	267.0	arCOG05203@1|root,32RHJ@2|Bacteria,1VBFD@1239|Firmicutes,24Q1N@186801|Clostridia,36JY2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5400505_36	768706.Desor_1562	2.158e-08	58.0	COG1878@1|root,COG1878@2|Bacteria,1USBQ@1239|Firmicutes,249A8@186801|Clostridia,26583@186807|Peptococcaceae	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
HKD1_k127_5400505_33	1476973.JMMB01000007_gene312	2.089e-14	76.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes,24CPD@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HKD1_k127_5413805_54	1301100.HG529386_gene5091	9.777e-159	501.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD1_k127_5413805_42	1476973.JMMB01000007_gene3066	2.528e-189	594.0	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,24B2X@186801|Clostridia,25SNA@186804|Peptostreptococcaceae	186801|Clostridia	K	Putative sugar-binding domain	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
HKD1_k127_5413805_28	1476973.JMMB01000007_gene3067	6.321e-233	726.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,25R2W@186804|Peptostreptococcaceae	186801|Clostridia	K	RNA polymerase	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
HKD1_k127_5413805_48	1476973.JMMB01000007_gene3068	7.412e-170	535.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,25QSQ@186804|Peptostreptococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HKD1_k127_5413805_59	1476973.JMMB01000007_gene3069	7.654e-150	475.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,25QGQ@186804|Peptostreptococcaceae	186801|Clostridia	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD1_k127_5413805_116	1408823.AXUS01000016_gene1038	4.746e-17	84.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia	186801|Clostridia	S	PFAM Small, acid-soluble spore proteins, alpha beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD1_k127_5413805_34	1476973.JMMB01000007_gene3071	8.402e-202	632.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,25R7F@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	dapL	-	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HKD1_k127_5413805_41	1476973.JMMB01000007_gene3072	8.947e-191	598.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,25RTV@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD1_k127_5413805_49	1476973.JMMB01000007_gene3073	5.181e-169	533.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,25RC9@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HKD1_k127_5413805_66	1476973.JMMB01000007_gene3074	4.207e-140	447.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,25QY3@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
HKD1_k127_5413805_71	1476973.JMMB01000007_gene3075	1.676e-131	422.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,248RU@186801|Clostridia,25QU4@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	DapH_N,Hexapep
HKD1_k127_5413805_98	1476973.JMMB01000007_gene415	2.763e-56	203.0	29UBZ@1|root,30FNB@2|Bacteria,1UEAA@1239|Firmicutes,25J5P@186801|Clostridia,25TP4@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_39	1476973.JMMB01000007_gene414	2.963e-195	615.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25SU4@186804|Peptostreptococcaceae	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_5413805_73	1476973.JMMB01000007_gene413	2.073e-125	403.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,25SQG@186804|Peptostreptococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5413805_99	1408823.AXUS01000001_gene620	6.428e-53	199.0	COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,25CIX@186801|Clostridia,25UMI@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_5413805_115	1301100.HG529244_gene2329	2.585e-20	92.0	2DEMU@1|root,2ZNHZ@2|Bacteria,1W2BP@1239|Firmicutes,256SG@186801|Clostridia,36TS3@31979|Clostridiaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_3
HKD1_k127_5413805_63	1292035.H476_1443	6.773e-141	460.0	COG0642@1|root,COG0642@2|Bacteria,1V7G1@1239|Firmicutes,25ER0@186801|Clostridia,25S8E@186804|Peptostreptococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HKD1_k127_5413805_95	272563.CD630_32550	3.639e-63	224.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HKD1_k127_5413805_87	1476973.JMMB01000007_gene3084	2.652e-93	309.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,24IBK@186801|Clostridia,25TGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
HKD1_k127_5413805_85	1476973.JMMB01000007_gene3092	1.483e-106	347.0	COG0634@1|root,COG0634@2|Bacteria,1V2K7@1239|Firmicutes,248P7@186801|Clostridia,25RAQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16720	Pribosyltran
HKD1_k127_5413805_27	1476973.JMMB01000007_gene3093	1.728e-234	730.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,25R1P@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
HKD1_k127_5413805_14	1476973.JMMB01000007_gene3094	1.183e-320	987.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25QR6@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-54 interaction domain protein	ygeV	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat,SpoVT_C
HKD1_k127_5413805_84	1476973.JMMB01000007_gene3095	1.878e-108	352.0	COG0500@1|root,COG2226@2|Bacteria,1VUD8@1239|Firmicutes,24ZYE@186801|Clostridia,25TAG@186804|Peptostreptococcaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD1_k127_5413805_75	1301100.HG529384_gene4109	7.988e-122	392.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,36DDV@31979|Clostridiaceae	186801|Clostridia	L	PFAM single-strand binding protein	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
HKD1_k127_5413805_67	1476973.JMMB01000007_gene3097	1.429e-139	446.0	COG0726@1|root,COG0726@2|Bacteria,1UZGG@1239|Firmicutes,249C9@186801|Clostridia,25QTV@186804|Peptostreptococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5413805_110	1476973.JMMB01000007_gene3098	2.678e-30	122.0	29URC@1|root,30G3B@2|Bacteria,1UF4B@1239|Firmicutes,25K53@186801|Clostridia,25UDT@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_108	1476973.JMMB01000007_gene3099	1.682e-31	123.0	2BB7F@1|root,324Q3@2|Bacteria,1UQWZ@1239|Firmicutes,258PY@186801|Clostridia,25TZ5@186804|Peptostreptococcaceae	186801|Clostridia	S	Small, acid-soluble spore proteins, alpha/beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HKD1_k127_5413805_86	1476973.JMMB01000007_gene3100	1.139e-102	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,25RBR@186804|Peptostreptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
HKD1_k127_5413805_57	1476973.JMMB01000007_gene3101	1.642e-154	491.0	COG3391@1|root,COG3391@2|Bacteria,1VD1U@1239|Firmicutes,25AE3@186801|Clostridia,25R2U@186804|Peptostreptococcaceae	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_104	1301100.HG529384_gene4103	5.614e-42	154.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,36MNV@31979|Clostridiaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
HKD1_k127_5413805_23	1476973.JMMB01000007_gene3103	2.425e-247	767.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25QCF@186804|Peptostreptococcaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HKD1_k127_5413805_80	1476973.JMMB01000007_gene3110	1.519e-111	363.0	28IW6@1|root,2Z8UG@2|Bacteria,1VS5J@1239|Firmicutes,25DWG@186801|Clostridia	186801|Clostridia	S	YvbH-like oligomerisation region	-	-	-	-	-	-	-	-	-	-	-	-	YvbH_ext,bPH_1
HKD1_k127_5413805_61	1476973.JMMB01000007_gene2691	6.534e-146	467.0	COG0730@1|root,COG0730@2|Bacteria,1V5K2@1239|Firmicutes,25CS2@186801|Clostridia,25SRM@186804|Peptostreptococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
HKD1_k127_5413805_36	1476973.JMMB01000007_gene2692	9.268e-201	627.0	COG3938@1|root,COG3938@2|Bacteria,1TQ61@1239|Firmicutes,2487S@186801|Clostridia,25SMF@186804|Peptostreptococcaceae	186801|Clostridia	E	Proline racemase	prdF	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
HKD1_k127_5413805_91	1292035.H476_3039	1.217e-85	284.0	COG0252@1|root,COG0252@2|Bacteria,1V5HP@1239|Firmicutes,24GD5@186801|Clostridia,25SP5@186804|Peptostreptococcaceae	186801|Clostridia	EJ	Glycine/sarcosine/betaine reductase component B subunits	prdE	-	-	ko:K10796	-	-	-	-	ko00000	-	-	-	Gly_reductase
HKD1_k127_5413805_68	1476973.JMMB01000007_gene2694	2.214e-137	439.0	COG5275@1|root,COG5275@2|Bacteria,1UZHN@1239|Firmicutes,24C77@186801|Clostridia,25SC9@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase component B subunits	prdD	-	1.21.4.1	ko:K10793,ko:K10795	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	Gly_reductase
HKD1_k127_5413805_103	272563.CD630_32410	1.809e-46	168.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,25S4M@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
HKD1_k127_5413805_88	1476973.JMMB01000007_gene2696	2.831e-91	301.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,25S4M@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
HKD1_k127_5413805_100	1476973.JMMB01000007_gene2697	3.934e-52	184.0	2BWPJ@1|root,32YWH@2|Bacteria,1VFE6@1239|Firmicutes,24QJI@186801|Clostridia,25TRN@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_9	1476973.JMMB01000007_gene2698	0.0	1091.0	COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,25SZX@186804|Peptostreptococcaceae	186801|Clostridia	EJ	D-proline reductase	prdA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114	1.21.4.1	ko:K10793	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	Gly_reductase
HKD1_k127_5413805_26	1391646.AVSU01000037_gene2105	3.846e-235	730.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,25SKE@186804|Peptostreptococcaceae	186801|Clostridia	C	electron transport complex protein RnfC K03615	prdC	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,RnfC_N
HKD1_k127_5413805_30	1476973.JMMB01000007_gene2700	3.803e-222	694.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25S3J@186804|Peptostreptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
HKD1_k127_5413805_96	1476973.JMMB01000007_gene2700	5.225e-63	219.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25S3J@186804|Peptostreptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
HKD1_k127_5413805_56	1391646.AVSU01000068_gene716	8.825e-155	494.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,25S7Z@186804|Peptostreptococcaceae	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
HKD1_k127_5413805_2	1476973.JMMB01000007_gene3111	0.0	1763.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25QNK@186804|Peptostreptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HKD1_k127_5413805_82	1301100.HG529383_gene4097	3.249e-110	362.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,36G9H@31979|Clostridiaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_5413805_83	1476973.JMMB01000007_gene3113	4.324e-109	360.0	COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,25D3F@186801|Clostridia,25SE7@186804|Peptostreptococcaceae	186801|Clostridia	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1
HKD1_k127_5413805_21	1301100.HG529382_gene4033	1.835e-267	826.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HKD1_k127_5413805_81	1476973.JMMB01000007_gene3118	2.603e-111	362.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25RV3@186804|Peptostreptococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HKD1_k127_5413805_58	1476973.JMMB01000007_gene3119	1.825e-151	480.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,25QFV@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HKD1_k127_5413805_60	1476973.JMMB01000007_gene3120	5.224e-149	474.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,25QEN@186804|Peptostreptococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD1_k127_5413805_55	1476973.JMMB01000007_gene3121	2.133e-158	503.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,25QCJ@186804|Peptostreptococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HKD1_k127_5413805_69	1301100.HG529382_gene4028	8.487e-134	430.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,36F61@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HKD1_k127_5413805_10	1476973.JMMB01000007_gene3123	0.0	1062.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,25QNS@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD1_k127_5413805_52	1476973.JMMB01000007_gene3124	2.046e-161	511.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,25M07@186801|Clostridia,25SN5@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_5413805_77	1476973.JMMB01000007_gene3125	2.1e-120	389.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,25RFU@186804|Peptostreptococcaceae	186801|Clostridia	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
HKD1_k127_5413805_62	1476973.JMMB01000007_gene3126	2.679e-142	455.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,25SIF@186804|Peptostreptococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
HKD1_k127_5413805_112	1476973.JMMB01000007_gene3127	1.159e-23	101.0	291FR@1|root,2ZP2I@2|Bacteria,1W22X@1239|Firmicutes,25522@186801|Clostridia,25S0T@186804|Peptostreptococcaceae	186801|Clostridia	S	Spo0E like sporulation regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoOE-like
HKD1_k127_5413805_105	632245.CLP_2468	3.092e-39	162.0	COG3976@1|root,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia	186801|Clostridia	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
HKD1_k127_5413805_79	632245.CLP_2469	1.059e-111	375.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,36W9X@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
HKD1_k127_5413805_106	1301100.HG529382_gene4022	3.283e-35	135.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,36MTC@31979|Clostridiaceae	186801|Clostridia	P	ferrous iron transport protein	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HKD1_k127_5413805_15	272563.CD630_32740	5.19e-312	966.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25QWT@186804|Peptostreptococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate,P12
HKD1_k127_5413805_40	1476973.JMMB01000007_gene3130	5.934e-193	606.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25R05@186804|Peptostreptococcaceae	186801|Clostridia	M	Trypsin-like peptidase domain	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HKD1_k127_5413805_18	1476973.JMMB01000007_gene3131	2.079e-282	869.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25QK4@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HKD1_k127_5413805_13	1476973.JMMB01000007_gene3133	1.05e-321	987.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25QFR@186804|Peptostreptococcaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
HKD1_k127_5413805_101	1476973.JMMB01000007_gene3134	1.022e-50	181.0	29UIM@1|root,30FVT@2|Bacteria,1UER9@1239|Firmicutes,25JR0@186801|Clostridia,25U10@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_94	1301100.HG529382_gene4016	5.642e-68	232.0	2F3NP@1|root,33WFP@2|Bacteria,1VVGT@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_38	1476973.JMMB01000007_gene3136	1.649e-195	614.0	COG3012@1|root,COG3012@2|Bacteria,1V0U4@1239|Firmicutes,24FCY@186801|Clostridia,25RUX@186804|Peptostreptococcaceae	186801|Clostridia	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384,HTH_psq,SEC-C
HKD1_k127_5413805_102	1476973.JMMB01000007_gene3137	3.236e-48	177.0	29UQ4@1|root,30G1V@2|Bacteria,1UF1W@1239|Firmicutes,25K2I@186801|Clostridia,25U7V@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_109	1476973.JMMB01000007_gene3138	5.833e-31	127.0	2975Z@1|root,2ZUDW@2|Bacteria,1W3HF@1239|Firmicutes,2567I@186801|Clostridia,25U7X@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
HKD1_k127_5413805_90	1476973.JMMB01000007_gene3139	1.806e-89	302.0	COG4972@1|root,COG4972@2|Bacteria,1VV9T@1239|Firmicutes,25EXN@186801|Clostridia,25RUM@186804|Peptostreptococcaceae	186801|Clostridia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
HKD1_k127_5413805_117	1476973.JMMB01000007_gene3140	2.13e-12	69.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,25N77@186801|Clostridia,25RX1@186804|Peptostreptococcaceae	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
HKD1_k127_5413805_113	1476973.JMMB01000007_gene3140	3.297e-21	96.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,25N77@186801|Clostridia,25RX1@186804|Peptostreptococcaceae	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
HKD1_k127_5413805_50	1476973.JMMB01000007_gene3141	3.311e-165	527.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25QTI@186804|Peptostreptococcaceae	186801|Clostridia	U	Bacterial type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HKD1_k127_5413805_29	1476973.JMMB01000007_gene3142	1.017e-230	720.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,25QCW@186804|Peptostreptococcaceae	186801|Clostridia	NU	Type II IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
HKD1_k127_5413805_111	1286171.EAL2_c16190	2.819e-30	130.0	COG3879@1|root,COG3879@2|Bacteria,1VDG3@1239|Firmicutes,24PW0@186801|Clostridia	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
HKD1_k127_5413805_33	1476973.JMMB01000007_gene3144	6.725e-203	634.0	COG1763@1|root,COG1763@2|Bacteria,1UI2K@1239|Firmicutes,24A23@186801|Clostridia,25R72@186804|Peptostreptococcaceae	186801|Clostridia	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_74	1476973.JMMB01000007_gene3145	6.317e-123	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25QD6@186804|Peptostreptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HKD1_k127_5413805_3	1476973.JMMB01000007_gene3146	0.0	1415.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25R33@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HKD1_k127_5413805_22	1476973.JMMB01000007_gene3150	6.144e-254	785.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25QFC@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HKD1_k127_5413805_78	1476973.JMMB01000007_gene3151	2.031e-116	375.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,25QQZ@186804|Peptostreptococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HKD1_k127_5413805_24	1476973.JMMB01000007_gene3152	3.042e-243	755.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25R85@186804|Peptostreptococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HKD1_k127_5413805_93	1476973.JMMB01000007_gene3153	1.633e-76	258.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25RHX@186804|Peptostreptococcaceae	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HKD1_k127_5413805_20	1476973.JMMB01000007_gene3154	2.083e-277	855.0	COG0127@1|root,COG0689@1|root,COG0127@2|Bacteria,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,25QCQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
HKD1_k127_5413805_6	1476973.JMMB01000007_gene3155	0.0	1164.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25R5S@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HKD1_k127_5413805_47	1476973.JMMB01000007_gene3156	5.336e-170	538.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,25QVP@186804|Peptostreptococcaceae	186801|Clostridia	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HKD1_k127_5413805_64	1196322.A370_00645	2.004e-140	452.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,36ECU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,Nitro_FeMo-Co,ZT_dimer
HKD1_k127_5413805_25	926561.KB900621_gene2829	8.328e-243	762.0	COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,2484W@186801|Clostridia	186801|Clostridia	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
HKD1_k127_5413805_19	1476973.JMMB01000007_gene3157	9.106e-281	865.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25QYW@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HKD1_k127_5413805_76	1301100.HG529379_gene3991	1.87e-120	390.0	29NU7@1|root,309SB@2|Bacteria,1V68J@1239|Firmicutes,24HMM@186801|Clostridia,36M13@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5413805_12	1476973.JMMB01000007_gene3159	0.0	1014.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25R6V@186804|Peptostreptococcaceae	186801|Clostridia	U	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
HKD1_k127_5413805_11	1476973.JMMB01000007_gene3160	0.0	1045.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25QHI@186804|Peptostreptococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HKD1_k127_5413805_37	1476973.JMMB01000007_gene3161	2.868e-198	619.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,25QRB@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HKD1_k127_5413805_0	1476973.JMMB01000007_gene3162	0.0	2188.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25QW9@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HKD1_k127_5413805_43	1476973.JMMB01000007_gene3163	7.892e-183	574.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,25QUI@186804|Peptostreptococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HKD1_k127_5413805_92	1476973.JMMB01000007_gene3164	2.508e-84	280.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,25REQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HKD1_k127_5413805_31	1476973.JMMB01000007_gene3165	2.584e-218	679.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25R0X@186804|Peptostreptococcaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
HKD1_k127_5413805_44	1476973.JMMB01000007_gene3166	2.275e-176	554.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,25QN8@186804|Peptostreptococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HKD1_k127_5413805_72	1476973.JMMB01000007_gene3167	1.56e-129	415.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,24CMU@186801|Clostridia,25QY2@186804|Peptostreptococcaceae	186801|Clostridia	E	DNA polymerase alpha chain like domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
HKD1_k127_5413805_46	1476973.JMMB01000007_gene3168	1.434e-172	544.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,25QY4@186804|Peptostreptococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HKD1_k127_5413805_70	1476973.JMMB01000007_gene3169	3.376e-132	425.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,25R02@186804|Peptostreptococcaceae	186801|Clostridia	P	Formate/nitrite transporter	fdhC	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
HKD1_k127_5413805_53	1476973.JMMB01000007_gene3170	3.779e-159	504.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,25SH9@186804|Peptostreptococcaceae	186801|Clostridia	P	Formate/nitrite transporter	fnt	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
HKD1_k127_5413805_17	1476973.JMMB01000007_gene3171	2.968e-288	888.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25SZI@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HKD1_k127_5413805_89	1301100.HG529378_gene4083	8.232e-91	301.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,36IZJ@31979|Clostridiaceae	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.12.1.3,1.6.5.3	ko:K00334,ko:K18330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07215	2Fe-2S_thioredx
HKD1_k127_5413805_4	1476973.JMMB01000007_gene3173	0.0	1219.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,25SMK@186804|Peptostreptococcaceae	186801|Clostridia	C	COG COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HKD1_k127_5413805_7	1476973.JMMB01000007_gene3174	0.0	1121.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25QUE@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07205	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
HKD1_k127_5413805_45	1301100.HG529378_gene4080	8.2e-174	548.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,36F8F@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HKD1_k127_5413805_8	1301100.HG529378_gene4079	0.0	1103.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,36DMH@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HKD1_k127_5413805_16	1301100.HG529378_gene4078	7.429e-292	902.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae	186801|Clostridia	E	Family 5	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
HKD1_k127_5413805_107	1476973.JMMB01000007_gene3178	2.251e-34	135.0	29V24@1|root,30GFA@2|Bacteria,1UHD1@1239|Firmicutes,25P30@186801|Clostridia,25U9V@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3899
HKD1_k127_5413805_51	1476973.JMMB01000007_gene3179	5.811e-165	522.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25SRA@186804|Peptostreptococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HKD1_k127_5413805_35	1301100.HG529378_gene4076	4.538e-201	628.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
HKD1_k127_5413805_32	1301100.HG529378_gene4075	3.205e-204	637.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD1_k127_5413805_65	1169144.KB910927_gene1338	2.89e-140	451.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus	91061|Bacilli	E	Belongs to the ABC transporter superfamily	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HKD1_k127_5413805_1	1476973.JMMB01000007_gene3184	0.0	1787.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,25QCP@186804|Peptostreptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HKD1_k127_5413805_5	1301100.HG529378_gene4072	0.0	1209.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,36DSR@31979|Clostridiaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HKD1_k127_5413805_97	332101.JIBU02000076_gene3848	4.061e-60	222.0	COG2199@1|root,COG2199@2|Bacteria,1TT99@1239|Firmicutes,24CR1@186801|Clostridia,36KG9@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HKD1_k127_5413805_121	411459.RUMOBE_04123	0.0002177	44.0	2EU6P@1|root,33MP7@2|Bacteria,1VM14@1239|Firmicutes,24U4C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5425989_21	1476973.JMMB01000007_gene3215	5.531e-32	126.0	2DR0U@1|root,339Q9@2|Bacteria,1VN9R@1239|Firmicutes,24VGB@186801|Clostridia,25RU2@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HKD1_k127_5425989_17	1476973.JMMB01000007_gene3214	4.368e-52	186.0	2E5CI@1|root,3304M@2|Bacteria,1VGE2@1239|Firmicutes,24RE0@186801|Clostridia,25S0G@186804|Peptostreptococcaceae	186801|Clostridia	S	ATP synthase I chain	atpI2	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
HKD1_k127_5425989_8	1476973.JMMB01000007_gene3213	1.747e-116	379.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25R3A@186804|Peptostreptococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HKD1_k127_5425989_20	1301100.HG529431_gene1778	4.112e-32	126.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,36MIS@31979|Clostridiaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HKD1_k127_5425989_12	1476973.JMMB01000007_gene3211	2.518e-82	275.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25RMQ@186804|Peptostreptococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01170	ATP-synt_B
HKD1_k127_5425989_11	1476973.JMMB01000007_gene3210	2.775e-90	299.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,25RIK@186804|Peptostreptococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HKD1_k127_5425989_1	1301100.HG529431_gene1775	1.024e-305	939.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,36ENE@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HKD1_k127_5425989_6	1301100.HG529431_gene1774	6.035e-148	472.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,36G24@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HKD1_k127_5425989_2	1301100.HG529431_gene1773	5.423e-283	871.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,36ERS@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD1_k127_5425989_18	1476973.JMMB01000007_gene3206	7.974e-46	166.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25RTG@186804|Peptostreptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
HKD1_k127_5425989_16	1301100.HG529431_gene1771	1.568e-63	219.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,36KTT@31979|Clostridiaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
HKD1_k127_5425989_13	1476973.JMMB01000007_gene3204	6.044e-79	265.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,25TEH@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HKD1_k127_5425989_9	1476973.JMMB01000007_gene3203	2.398e-100	329.0	COG2834@1|root,COG2834@2|Bacteria,1VQK5@1239|Firmicutes,24NV8@186801|Clostridia,25RM1@186804|Peptostreptococcaceae	186801|Clostridia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
HKD1_k127_5425989_4	1476973.JMMB01000007_gene3202	2.466e-205	643.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25R0S@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HKD1_k127_5425989_22	1128398.Curi_c20810	3.214e-15	79.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,24QKP@186801|Clostridia,26CEG@186813|unclassified Clostridiales	186801|Clostridia	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
HKD1_k127_5425989_14	1476973.JMMB01000007_gene3200	2.729e-68	233.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,25REC@186804|Peptostreptococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HKD1_k127_5425989_7	445973.CLOBAR_02563	1.933e-147	470.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25QJW@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HKD1_k127_5425989_5	1476973.JMMB01000007_gene3198	2.189e-180	567.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25QQ5@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HKD1_k127_5425989_15	1476973.JMMB01000007_gene3197	7.756e-68	234.0	2E0BG@1|root,32VYP@2|Bacteria,1VD9B@1239|Firmicutes,24PIR@186801|Clostridia,25RP5@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
HKD1_k127_5425989_0	1476973.JMMB01000007_gene3196	0.0	1380.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,25S4X@186804|Peptostreptococcaceae	186801|Clostridia	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
HKD1_k127_5425989_10	1301100.HG529431_gene1761	1.011e-97	322.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,36JPF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HKD1_k127_5425989_3	1476973.JMMB01000007_gene3194	1.566e-210	658.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25QD4@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HKD1_k127_5425989_19	1476973.JMMB01000007_gene3192	6.335e-35	134.0	28YAU@1|root,2ZK5I@2|Bacteria,1W64V@1239|Firmicutes,257I1@186801|Clostridia,25RYF@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5435129_25	86416.Clopa_0037	1.255e-36	141.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia,36KC1@31979|Clostridiaceae	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
HKD1_k127_5435129_16	1487921.DP68_01155	3.231e-88	295.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,36E69@31979|Clostridiaceae	186801|Clostridia	KO	Hydrogenase accessory protein HypB	ureG	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
HKD1_k127_5435129_0	1487921.DP68_01160	2.873e-279	877.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,36EAU@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
HKD1_k127_5435129_27	1487921.DP68_01165	1.011e-24	104.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,24UXU@186801|Clostridia,36NYN@31979|Clostridiaceae	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
HKD1_k127_5435129_10	1487921.DP68_01170	1.568e-137	445.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,36FKI@31979|Clostridiaceae	186801|Clostridia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
HKD1_k127_5435129_8	1487921.DP68_01175	2.685e-144	464.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,36GDV@31979|Clostridiaceae	186801|Clostridia	O	PFAM AIR synthase related protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HKD1_k127_5435129_12	1476973.JMMB01000007_gene2347	2.665e-109	356.0	2B9GQ@1|root,2ZCFA@2|Bacteria,1UPR4@1239|Firmicutes,25HMD@186801|Clostridia,25UQ8@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5435129_11	1476973.JMMB01000007_gene2346	1.258e-126	406.0	COG1251@1|root,COG1251@2|Bacteria,1UZNP@1239|Firmicutes,24951@186801|Clostridia,25QX6@186804|Peptostreptococcaceae	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	-	-	-	-	-	-	-	-	-	-	NIR_SIR,NIR_SIR_ferr
HKD1_k127_5435129_26	1476973.JMMB01000007_gene2345	3.801e-28	113.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,25RY4@186804|Peptostreptococcaceae	186801|Clostridia	D	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
HKD1_k127_5435129_13	1476973.JMMB01000007_gene1932	7.394e-107	353.0	COG4461@1|root,COG4461@2|Bacteria,1VDVF@1239|Firmicutes,24N0M@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
HKD1_k127_5435129_21	1476973.JMMB01000007_gene2344	1.682e-55	195.0	2BGS0@1|root,30GTC@2|Bacteria,1UGKD@1239|Firmicutes,25P2W@186801|Clostridia,25TW3@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5435129_14	1476973.JMMB01000007_gene1731	2.087e-100	329.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,2495A@186801|Clostridia,25SMS@186804|Peptostreptococcaceae	186801|Clostridia	P	Carbonic anhydrase	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
HKD1_k127_5435129_19	1211817.CCAT010000085_gene1891	2.393e-73	257.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,36EYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HKD1_k127_5435129_17	1121289.JHVL01000008_gene1290	4.228e-75	259.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,36I3C@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter	zurA	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
HKD1_k127_5435129_18	1121289.JHVL01000008_gene1291	1.781e-73	256.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,36EWA@31979|Clostridiaceae	186801|Clostridia	P	ABC 3 transport family	adcB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HKD1_k127_5435129_28	1121121.KB894295_gene4393	4.148e-09	57.0	2BT1N@1|root,32N5W@2|Bacteria,1U223@1239|Firmicutes,4IBJ6@91061|Bacilli,270NT@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5435129_22	1476973.JMMB01000007_gene2341	1.532e-43	159.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,25TV6@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5435129_4	1476973.JMMB01000007_gene2289	1.633e-223	699.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25S9D@186804|Peptostreptococcaceae	186801|Clostridia	JKL	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
HKD1_k127_5435129_23	1476973.JMMB01000007_gene1862	1.279e-37	141.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25TZ4@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_5435129_2	86416.Clopa_0609	5.475e-250	781.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
HKD1_k127_5435129_24	1476973.JMMB01000007_gene1862	1.174e-36	138.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25TZ4@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_5435129_5	1301100.HG529275_gene1556	1.21e-181	572.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD1_k127_5435129_6	1301100.HG529275_gene1557	6.788e-156	496.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,36G1Q@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HKD1_k127_5435129_20	1301100.HG529275_gene1558	4.2e-61	212.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,36IY3@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
HKD1_k127_5435129_1	1301100.HG529275_gene1559	5.665e-264	820.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
HKD1_k127_5435129_7	1301100.HG529275_gene1560	2.981e-149	477.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HKD1_k127_5435129_9	1301100.HG529275_gene1561	2.02e-140	451.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,36DBX@31979|Clostridiaceae	186801|Clostridia	G	PFAM periplasmic binding protein	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HKD1_k127_5435129_3	1476973.JMMB01000007_gene2546	2.169e-241	758.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SPV@186804|Peptostreptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
HKD1_k127_5435129_15	1476973.JMMB01000007_gene2534	3.035e-100	332.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal
HKD1_k127_5483128_3	536233.CLO_1968	5.313e-156	499.0	COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,24EHV@186801|Clostridia,36GB2@31979|Clostridiaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD1_k127_5483128_7	1033737.CAEV01000001_gene2336	1.282e-111	366.0	COG0454@1|root,COG0456@2|Bacteria,1VFXT@1239|Firmicutes,24MQN@186801|Clostridia,36M89@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K06323	-	-	-	-	ko00000	-	-	-	Acetyltransf_1
HKD1_k127_5483128_11	545697.HMPREF0216_00898	5.413e-77	266.0	COG2768@1|root,COG2768@2|Bacteria,1UINS@1239|Firmicutes,25EPC@186801|Clostridia,36V16@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HKD1_k127_5483128_4	1292035.H476_2471	3.213e-138	442.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25S3P@186804|Peptostreptococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_5483128_0	1292035.H476_2472	3.666e-247	779.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25SK2@186804|Peptostreptococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD1_k127_5483128_9	1391646.AVSU01000099_gene342	1.316e-95	317.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25TQ6@186804|Peptostreptococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2,SH3_3,SPOR
HKD1_k127_5483128_1	1476973.JMMB01000007_gene2086	2.245e-236	734.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,25QZY@186804|Peptostreptococcaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
HKD1_k127_5483128_15	1476973.JMMB01000007_gene2148	2.048e-19	88.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HKD1_k127_5483128_10	931276.Cspa_c25470	1.115e-77	263.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,25B3M@186801|Clostridia,36W86@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
HKD1_k127_5483128_14	1151292.QEW_2540	1.17e-28	119.0	2AES4@1|root,314NX@2|Bacteria,1UU4J@1239|Firmicutes,255GS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5483128_12	999411.HMPREF1092_01766	3.545e-66	230.0	COG0500@1|root,COG0500@2|Bacteria,1UIRP@1239|Firmicutes,25EQI@186801|Clostridia,36URG@31979|Clostridiaceae	186801|Clostridia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HKD1_k127_5483128_8	632245.CLP_2469	1.526e-109	361.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,36W9X@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
HKD1_k127_5483128_13	632245.CLP_2468	7.712e-55	198.0	COG3976@1|root,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia	186801|Clostridia	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
HKD1_k127_5483128_5	545697.HMPREF0216_00876	1.403e-122	400.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,36DZZ@31979|Clostridiaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HKD1_k127_5483128_6	1301100.HG529429_gene1895	1.296e-114	372.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24973@186801|Clostridia,36GND@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_5483128_2	1151292.QEW_1398	1.032e-177	569.0	COG0642@1|root,COG2205@2|Bacteria,1UYC9@1239|Firmicutes,24CPQ@186801|Clostridia,25TFB@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_5486668_1	1476973.JMMB01000007_gene2917	0.0	1126.0	COG2247@1|root,COG3227@1|root,COG2247@2|Bacteria,COG3227@2|Bacteria,1TP08@1239|Firmicutes,24CIW@186801|Clostridia	186801|Clostridia	E	hmm pf01447	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
HKD1_k127_5486668_27	1301100.HG529226_gene4775	5.104e-174	548.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,36EIH@31979|Clostridiaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD1_k127_5486668_21	1476973.JMMB01000007_gene710	2.405e-200	626.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,25R7U@186804|Peptostreptococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HKD1_k127_5486668_24	1476973.JMMB01000007_gene711	3.613e-182	580.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,25QR1@186804|Peptostreptococcaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,CW_binding_1,CW_binding_2,Glucosaminidase,LRR_5,SH3_3,SLT,YkuD
HKD1_k127_5486668_48	1301100.HG529227_gene5450	5.414e-99	349.0	COG2247@1|root,COG2247@2|Bacteria	2|Bacteria	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_5486668_65	398511.BpOF4_06075	1.44e-23	117.0	COG2247@1|root,COG5386@1|root,COG2247@2|Bacteria,COG5386@2|Bacteria,1V4MK@1239|Firmicutes,4HI17@91061|Bacilli,1ZSBA@1386|Bacillus	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH,SWM_repeat
HKD1_k127_5486668_9	1301100.HG529227_gene5448	1.715e-252	784.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HKD1_k127_5486668_28	1301100.HG529227_gene5449	2.634e-173	551.0	COG0457@1|root,COG0457@2|Bacteria,1V0II@1239|Firmicutes,24C9M@186801|Clostridia	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX,DHHW
HKD1_k127_5486668_17	1301100.HG529227_gene5450	9.377e-219	717.0	COG2247@1|root,COG2247@2|Bacteria	2|Bacteria	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_5486668_51	1408823.AXUS01000008_gene2306	2.735e-82	301.0	COG2247@1|root,COG2247@2|Bacteria,1UYI7@1239|Firmicutes,2511I@186801|Clostridia,25REK@186804|Peptostreptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_5486668_57	1476973.JMMB01000007_gene722	8.599e-64	243.0	COG2247@1|root,COG2247@2|Bacteria,1UYI7@1239|Firmicutes,2511I@186801|Clostridia,25REK@186804|Peptostreptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_5486668_18	1408823.AXUS01000008_gene2326	2.273e-215	675.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD1_k127_5486668_25	1301100.HG529227_gene5467	3.395e-180	570.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,36WDK@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
HKD1_k127_5486668_30	1301100.HG529227_gene5468	1.853e-166	531.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,36EEX@31979|Clostridiaceae	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
HKD1_k127_5486668_20	1301100.HG529227_gene5469	1.461e-206	653.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_5486668_59	445973.CLOBAR_02355	1.168e-54	204.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia,25UFQ@186804|Peptostreptococcaceae	186801|Clostridia	M	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	spr	-	3.4.17.13	ko:K13694,ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
HKD1_k127_5486668_70	411469.EUBHAL_02751	1.208e-05	48.0	COG1686@1|root,COG1686@2|Bacteria,1V50I@1239|Firmicutes,24I5G@186801|Clostridia,25YWM@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
HKD1_k127_5486668_62	742723.HMPREF9477_01198	1.903e-39	153.0	2EAJ6@1|root,334N3@2|Bacteria,1UPSK@1239|Firmicutes,25HNB@186801|Clostridia,27UNT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
HKD1_k127_5486668_0	1476973.JMMB01000007_gene758	0.0	1305.0	COG0653@1|root,COG0653@2|Bacteria,1VTCD@1239|Firmicutes,24Z6V@186801|Clostridia,25R5P@186804|Peptostreptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
HKD1_k127_5486668_4	1476973.JMMB01000007_gene759	6.4e-323	998.0	COG0860@1|root,COG2247@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,1V6BP@1239|Firmicutes,25B61@186801|Clostridia,25UK7@186804|Peptostreptococcaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2
HKD1_k127_5486668_41	1301100.HG529227_gene5476	1.159e-117	381.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,36GR6@31979|Clostridiaceae	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
HKD1_k127_5486668_45	1476973.JMMB01000007_gene761	6.51e-109	362.0	COG2247@1|root,COG2247@2|Bacteria,1VU0B@1239|Firmicutes,24Y1Y@186801|Clostridia,25T7U@186804|Peptostreptococcaceae	186801|Clostridia	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_5486668_13	1301100.HG529227_gene5478	9.311e-238	744.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HKD1_k127_5486668_6	1301100.HG529227_gene5479	3.064e-307	948.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,36F97@31979|Clostridiaceae	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HKD1_k127_5486668_19	1476973.JMMB01000007_gene764	3.069e-207	647.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,25T1R@186804|Peptostreptococcaceae	186801|Clostridia	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HKD1_k127_5486668_38	1476973.JMMB01000007_gene765	2.223e-138	442.0	COG3774@1|root,COG3774@2|Bacteria,1V3YG@1239|Firmicutes,24J8S@186801|Clostridia,25RN7@186804|Peptostreptococcaceae	186801|Clostridia	M	Capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth,Gb3_synth,Gly_transf_sug
HKD1_k127_5486668_31	1301100.HG529227_gene5482	1.559e-165	528.0	2BZ2G@1|root,33Q7Z@2|Bacteria,1VUAY@1239|Firmicutes,24Z4G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_34	1301100.HG529227_gene5483	1.062e-159	505.0	COG1216@1|root,COG1216@2|Bacteria,1VU0Z@1239|Firmicutes,25BB3@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5486668_16	1476973.JMMB01000007_gene768	1.4e-223	696.0	COG1887@1|root,COG1887@2|Bacteria,1TPMB@1239|Firmicutes,24N4F@186801|Clostridia,25T1S@186804|Peptostreptococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HKD1_k127_5486668_40	1476973.JMMB01000007_gene769	4.327e-130	418.0	COG1215@1|root,COG1215@2|Bacteria,1VUUB@1239|Firmicutes,25EXJ@186801|Clostridia,25RVG@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5486668_36	500633.CLOHIR_00968	5.219e-152	484.0	COG0463@1|root,COG0463@2|Bacteria,1V8T1@1239|Firmicutes,24E8C@186801|Clostridia,25TRZ@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5486668_37	1301100.HG529227_gene5487	7.592e-142	452.0	COG0463@1|root,COG0463@2|Bacteria,1TSFF@1239|Firmicutes,24IBH@186801|Clostridia,36V9F@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	ko:K12997,ko:K16698	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HKD1_k127_5486668_10	1476973.JMMB01000007_gene772	3.599e-252	781.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,25R47@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ywqF	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HKD1_k127_5486668_68	1476973.JMMB01000007_gene773	3.196e-06	50.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,25R21@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
HKD1_k127_5486668_44	1476973.JMMB01000007_gene775	2.868e-110	361.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1VE8F@1239|Firmicutes,24XXC@186801|Clostridia,25TIC@186804|Peptostreptococcaceae	186801|Clostridia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
HKD1_k127_5486668_2	1476973.JMMB01000007_gene776	0.0	1101.0	COG1649@1|root,COG2247@1|root,COG1649@2|Bacteria,COG2247@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25R0T@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
HKD1_k127_5486668_29	1476973.JMMB01000007_gene777	1.336e-166	528.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25QGN@186804|Peptostreptococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD1_k127_5486668_32	272563.CD630_24910	2.487e-160	509.0	COG1482@1|root,COG1482@2|Bacteria,1UIGK@1239|Firmicutes,25EN2@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
HKD1_k127_5486668_55	1476973.JMMB01000007_gene778	8.441e-69	240.0	2FCQH@1|root,344TQ@2|Bacteria,1W1DU@1239|Firmicutes,251BS@186801|Clostridia,25U9D@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_50	1301100.HG529227_gene5494	9.701e-94	310.0	2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,24JEJ@186801|Clostridia,36IVT@31979|Clostridiaceae	186801|Clostridia	S	Putative amidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
HKD1_k127_5486668_39	1301100.HG529227_gene5500	1.459e-132	423.0	COG0020@1|root,COG0020@2|Bacteria,1TRKB@1239|Firmicutes,248R2@186801|Clostridia,36EV1@31979|Clostridiaceae	186801|Clostridia	I	undecaprenyl	uppS1	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HKD1_k127_5486668_47	1476973.JMMB01000007_gene781	1.435e-106	352.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24PR4@186801|Clostridia,25RIY@186804|Peptostreptococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,GHL10
HKD1_k127_5486668_33	1476973.JMMB01000007_gene782	7.353e-160	509.0	COG3621@1|root,COG3621@2|Bacteria,1V83Q@1239|Firmicutes,24AVQ@186801|Clostridia,25SCX@186804|Peptostreptococcaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_5486668_7	1476973.JMMB01000007_gene783	7.129e-276	858.0	COG0286@1|root,COG0286@2|Bacteria,1UMSN@1239|Firmicutes,24856@186801|Clostridia,25QCH@186804|Peptostreptococcaceae	186801|Clostridia	V	TaqI-like C-terminal specificity domain	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase,TaqI_C
HKD1_k127_5486668_60	1476973.JMMB01000007_gene784	7.268e-50	179.0	29UNU@1|root,30G0E@2|Bacteria,1UEZ2@1239|Firmicutes,2524V@186801|Clostridia,25TYZ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_15	1476973.JMMB01000007_gene785	1.35e-229	714.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,25R31@186804|Peptostreptococcaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
HKD1_k127_5486668_61	1301100.HG529227_gene5510	3.109e-40	150.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,36KJQ@31979|Clostridiaceae	186801|Clostridia	G	HPr family	ptsH	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
HKD1_k127_5486668_3	1301100.HG529227_gene5511	0.0	1022.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HKD1_k127_5486668_26	1476973.JMMB01000007_gene788	5.783e-179	565.0	COG3641@1|root,COG3641@2|Bacteria,1UNZM@1239|Firmicutes,24A9C@186801|Clostridia,25SI0@186804|Peptostreptococcaceae	186801|Clostridia	S	Phosphotransferase system, EIIC	pfoR	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIC_2
HKD1_k127_5486668_23	1301100.HG529227_gene5513	2.608e-195	611.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,36DK2@31979|Clostridiaceae	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
HKD1_k127_5486668_58	1301100.HG529227_gene5514	2.229e-56	199.0	COG3339@1|root,COG3339@2|Bacteria,1VYQF@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
HKD1_k127_5486668_22	1476973.JMMB01000007_gene792	2.506e-198	621.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25R6N@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD1_k127_5486668_49	1476973.JMMB01000007_gene793	3.359e-97	320.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25RBZ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD1_k127_5486668_35	1476973.JMMB01000007_gene804	9.681e-156	495.0	COG0671@1|root,COG0671@2|Bacteria,1V01Y@1239|Firmicutes,24DFI@186801|Clostridia,25QGY@186804|Peptostreptococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HKD1_k127_5486668_11	1476973.JMMB01000007_gene805	7.543e-240	744.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,25QCZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD1_k127_5486668_63	1301100.HG529228_gene5373	1.628e-32	126.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes	1239|Firmicutes	S	'small, acid-soluble spore protein	sspA	-	-	ko:K06418,ko:K06419,ko:K06420,ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HKD1_k127_5486668_64	1476973.JMMB01000007_gene807	9.176e-27	109.0	2EDV7@1|root,337QC@2|Bacteria,1VEH5@1239|Firmicutes,24SJC@186801|Clostridia,25U3B@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_53	1476973.JMMB01000007_gene808	2.319e-73	249.0	2F52F@1|root,33XPU@2|Bacteria,1VWGN@1239|Firmicutes,250HP@186801|Clostridia,25RRP@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_54	1476973.JMMB01000007_gene809	4.41e-72	247.0	2CDG9@1|root,3401V@2|Bacteria,1VWPJ@1239|Firmicutes,25153@186801|Clostridia,25TJ0@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5486668_5	1476973.JMMB01000007_gene810	1.632e-316	975.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,24FPA@186801|Clostridia,25QW1@186804|Peptostreptococcaceae	186801|Clostridia	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
HKD1_k127_5486668_46	1476973.JMMB01000007_gene811	2.487e-108	352.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24IAS@186801|Clostridia,25RCH@186804|Peptostreptococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_5486668_14	1476973.JMMB01000007_gene812	3.764e-235	729.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25QQH@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HKD1_k127_5486668_52	485916.Dtox_0778	4.721e-76	269.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HKD1_k127_5486668_12	1476973.JMMB01000007_gene814	2.895e-238	740.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,25R80@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HKD1_k127_5486668_43	1476973.JMMB01000007_gene815	1.869e-112	364.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,25S2P@186804|Peptostreptococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,PTAC
HKD1_k127_5486668_56	1301100.HG529228_gene5384	1.565e-67	232.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24KBG@186801|Clostridia,36VX7@31979|Clostridiaceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD1_k127_5486668_42	1476973.JMMB01000007_gene817	6.222e-114	370.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,25S1S@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD1_k127_5486668_8	1476973.JMMB01000007_gene818	8.607e-266	820.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25QC0@186804|Peptostreptococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HKD1_k127_5488215_6	469617.FUAG_00857	1.723e-05	51.0	COG4824@1|root,COG4824@2|Bacteria,37AWU@32066|Fusobacteria	32066|Fusobacteria	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
HKD1_k127_5488215_2	642492.Clole_0841	2.045e-53	196.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
HKD1_k127_5488215_4	1292035.H476_0998	9.447e-18	92.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25TQ6@186804|Peptostreptococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2,SH3_3,SPOR
HKD1_k127_5488215_0	1031288.AXAA01000043_gene1772	2.555e-75	258.0	2DQXN@1|root,3398K@2|Bacteria,1UPZ2@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
HKD1_k127_5488215_1	1476973.JMMB01000009_gene3544	6.76e-62	218.0	COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,24IM3@186801|Clostridia,25TC4@186804|Peptostreptococcaceae	186801|Clostridia	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
HKD1_k127_5488215_3	1415774.U728_3781	3.685e-40	161.0	COG0433@1|root,COG0433@2|Bacteria,1V4Z4@1239|Firmicutes,24E9I@186801|Clostridia,36GXR@31979|Clostridiaceae	186801|Clostridia	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5500613_2	272563.CD630_16570	0.0	1255.0	COG0403@1|root,COG0404@1|root,COG0403@2|Bacteria,COG0404@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,25SVG@186804|Peptostreptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
HKD1_k127_5500613_3	272563.CD630_16580	5.794e-262	812.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,25S4U@186804|Peptostreptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	GDC-P
HKD1_k127_5500613_11	1292035.H476_1914	2.408e-118	388.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,25D2D@186801|Clostridia	186801|Clostridia	E	Belongs to the arginase family	rocF	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HKD1_k127_5500613_7	1476973.JMMB01000007_gene1557	9.712e-192	603.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,25R38@186804|Peptostreptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HKD1_k127_5500613_22	748224.HMPREF9436_02258	4.19e-56	203.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HKD1_k127_5500613_5	1476973.JMMB01000007_gene1559	1.006e-226	706.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,25QGS@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
HKD1_k127_5500613_19	1391646.AVSU01000131_gene2658	2.111e-86	287.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25S2Z@186804|Peptostreptococcaceae	186801|Clostridia	H	6,7-dimethyl-8-ribityllumazine synthase	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HKD1_k127_5500613_16	1301100.HG529303_gene3111	7.614e-95	315.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes,25CUT@186801|Clostridia,36X10@31979|Clostridiaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
HKD1_k127_5500613_20	1476973.JMMB01000007_gene1777	5.475e-68	238.0	COG1376@1|root,COG1376@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25QFI@186804|Peptostreptococcaceae	186801|Clostridia	T	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,PG_binding_1,SH3_3,YkuD
HKD1_k127_5500613_15	1476973.JMMB01000007_gene1779	7.691e-103	339.0	COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,24J9N@186801|Clostridia,25TC1@186804|Peptostreptococcaceae	186801|Clostridia	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
HKD1_k127_5500613_0	1391646.AVSU01000055_gene1111	0.0	1534.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25R4B@186804|Peptostreptococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HKD1_k127_5500613_21	1476973.JMMB01000007_gene1782	7.632e-66	228.0	COG2937@1|root,COG2937@2|Bacteria,1UEK9@1239|Firmicutes,25JIK@186801|Clostridia,25SQB@186804|Peptostreptococcaceae	186801|Clostridia	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5500613_24	1391646.AVSU01000015_gene3003	5.954e-49	177.0	2EJBW@1|root,33D30@2|Bacteria,1VDH3@1239|Firmicutes,24JQ8@186801|Clostridia,25TID@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HKD1_k127_5500613_13	1033737.CAEV01000024_gene3506	2.046e-108	357.0	2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,24I9M@186801|Clostridia,36JGD@31979|Clostridiaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HKD1_k127_5500613_17	1391646.AVSU01000147_gene3313	4.754e-92	307.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_5500613_8	1391646.AVSU01000147_gene3312	1.032e-156	509.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_5500613_18	1391646.AVSU01000151_gene2684	7.55e-88	295.0	COG0664@1|root,COG0664@2|Bacteria,1VBQR@1239|Firmicutes,25CK1@186801|Clostridia	186801|Clostridia	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_5500613_1	1301100.HG529329_gene4465	0.0	1287.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36DJA@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HKD1_k127_5500613_25	1391646.AVSU01000010_gene84	3.625e-41	153.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,25TF1@186804|Peptostreptococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HKD1_k127_5500613_6	1476973.JMMB01000007_gene1784	2.604e-211	661.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25R3B@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation diffusion facilitator family transporter	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HKD1_k127_5500613_10	1476973.JMMB01000007_gene1785	4.443e-120	387.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,25QM7@186804|Peptostreptococcaceae	186801|Clostridia	G	phosphoglycerate mutase	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HKD1_k127_5500613_4	1476973.JMMB01000007_gene1786	5.461e-229	712.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,25QU1@186804|Peptostreptococcaceae	186801|Clostridia	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HKD1_k127_5500613_23	1476973.JMMB01000007_gene1787	4.432e-56	198.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,25TMF@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
HKD1_k127_5500613_12	1476973.JMMB01000007_gene1788	2.447e-113	369.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,25RAW@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HKD1_k127_5500613_14	1476973.JMMB01000007_gene1789	6.713e-108	351.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,25RHW@186804|Peptostreptococcaceae	186801|Clostridia	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HKD1_k127_5500613_9	1476973.JMMB01000007_gene1790	2.839e-144	461.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,25R4P@186804|Peptostreptococcaceae	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
HKD1_k127_5500613_28	1476973.JMMB01000007_gene1859	3.031e-21	92.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25TZ4@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_5587209_7	1301100.HG529386_gene5091	1.728e-65	224.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HKD1_k127_5587209_3	1476973.JMMB01000007_gene3064	1.514e-244	757.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,25QZ9@186804|Peptostreptococcaceae	186801|Clostridia	F	phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HKD1_k127_5587209_4	1476973.JMMB01000007_gene3063	4.566e-150	477.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,25QK7@186804|Peptostreptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
HKD1_k127_5587209_1	1476973.JMMB01000007_gene3062	2.962e-306	942.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,25R4T@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HKD1_k127_5587209_2	1476973.JMMB01000007_gene3061	2.068e-261	808.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25QP6@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HKD1_k127_5587209_9	1476973.JMMB01000007_gene3058	1.652e-31	124.0	COG1314@1|root,COG1314@2|Bacteria,1VZ7C@1239|Firmicutes,25437@186801|Clostridia,25RTQ@186804|Peptostreptococcaceae	186801|Clostridia	U	Preprotein translocase, SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HKD1_k127_5587209_8	1476973.JMMB01000007_gene3057	7.222e-48	173.0	28V88@1|root,2ZHBB@2|Bacteria,1W4T3@1239|Firmicutes,257JU@186801|Clostridia,25RRV@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5587209_0	1476973.JMMB01000007_gene3056	0.0	1242.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,25QS9@186804|Peptostreptococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HKD1_k127_5587209_6	1476973.JMMB01000007_gene3055	1.666e-86	287.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25RAS@186804|Peptostreptococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HKD1_k127_5587209_5	929704.Myrod_3501	1.031e-139	460.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,4NVQN@976|Bacteroidetes,1IA90@117743|Flavobacteriia	976|Bacteroidetes	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC
HKD1_k127_5717678_16	1301100.HG529448_gene4772	2.797e-16	79.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,36E5N@31979|Clostridiaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HKD1_k127_5717678_11	1476973.JMMB01000007_gene171	1.18e-123	398.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,25QG1@186804|Peptostreptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
HKD1_k127_5717678_13	1476973.JMMB01000007_gene172	1.518e-98	323.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,25RM8@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
HKD1_k127_5717678_10	1476973.JMMB01000007_gene173	8.556e-148	469.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,25QG5@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HKD1_k127_5717678_9	1476973.JMMB01000007_gene174	1.31e-149	474.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25QWX@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HKD1_k127_5717678_15	1476973.JMMB01000007_gene175	4.717e-70	238.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,25RG2@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HKD1_k127_5717678_6	1301100.HG529433_gene6517	7.846e-282	869.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,36DSW@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HKD1_k127_5717678_17	1476973.JMMB01000007_gene177	3.695e-15	76.0	28TZU@1|root,2ZG69@2|Bacteria,1W66Y@1239|Firmicutes,254UF@186801|Clostridia,25UCK@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5717678_4	1476973.JMMB01000007_gene178	4.325e-311	955.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25QPF@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HKD1_k127_5717678_3	1476973.JMMB01000007_gene179	0.0	1059.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,25QIH@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
HKD1_k127_5717678_14	1476973.JMMB01000007_gene180	3.262e-91	301.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,25RCU@186804|Peptostreptococcaceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
HKD1_k127_5717678_12	1476973.JMMB01000007_gene181	6.508e-120	387.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25RGS@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
HKD1_k127_5717678_8	1476973.JMMB01000007_gene182	6.271e-200	626.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,25QEQ@186804|Peptostreptococcaceae	186801|Clostridia	S	PIN domain protein	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
HKD1_k127_5717678_7	1476973.JMMB01000007_gene183	4.656e-203	634.0	COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,247J4@186801|Clostridia,25QSP@186804|Peptostreptococcaceae	186801|Clostridia	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
HKD1_k127_5717678_5	1476973.JMMB01000007_gene184	1.095e-284	877.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25QSV@186804|Peptostreptococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
HKD1_k127_5717678_1	1476973.JMMB01000007_gene185	0.0	1374.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25QH6@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HKD1_k127_5717678_2	1476973.JMMB01000007_gene186	0.0	1174.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,25QW4@186804|Peptostreptococcaceae	186801|Clostridia	J	Elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HKD1_k127_5717678_0	1476973.JMMB01000007_gene187	0.0	2130.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25QUZ@186804|Peptostreptococcaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HKD1_k127_5782264_1	1301100.HG529437_gene6536	4.879e-85	282.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,36IRD@31979|Clostridiaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HKD1_k127_5782264_0	1476973.JMMB01000007_gene198	5.727e-266	820.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25R15@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HKD1_k127_5849793_14	1476973.JMMB01000007_gene889	4.3e-288	889.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25SVD@186804|Peptostreptococcaceae	186801|Clostridia	E	Sodium:alanine symporter family	yrbD	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HKD1_k127_5849793_71	1476973.JMMB01000007_gene890	1.708e-159	509.0	COG0845@1|root,COG0845@2|Bacteria,1VXBH@1239|Firmicutes,25JB0@186801|Clostridia,25RTE@186804|Peptostreptococcaceae	186801|Clostridia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_2
HKD1_k127_5849793_100	1476973.JMMB01000007_gene891	1.767e-119	387.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,25QMY@186804|Peptostreptococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HKD1_k127_5849793_119	1476973.JMMB01000007_gene892	4.056e-82	274.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,25RRB@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HKD1_k127_5849793_144	1476973.JMMB01000007_gene893	6.662e-37	140.0	COG0762@1|root,COG0762@2|Bacteria,1UEEV@1239|Firmicutes,25JBG@186801|Clostridia,25RUG@186804|Peptostreptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
HKD1_k127_5849793_79	1476973.JMMB01000007_gene894	3.769e-143	456.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,25RJ4@186804|Peptostreptococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
HKD1_k127_5849793_114	1476973.JMMB01000007_gene895	6.905e-91	301.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,25RDY@186804|Peptostreptococcaceae	186801|Clostridia	D	DivIVA protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HKD1_k127_5849793_0	1476973.JMMB01000007_gene896	0.0	2043.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25R14@186804|Peptostreptococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HKD1_k127_5849793_91	1476973.JMMB01000007_gene900	2.206e-127	409.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,25QGK@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_5849793_39	1476973.JMMB01000007_gene901	1.496e-206	643.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,25R0Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HKD1_k127_5849793_135	1476973.JMMB01000007_gene904	2.558e-63	218.0	2E46D@1|root,3092G@2|Bacteria,1U4C0@1239|Firmicutes,259DG@186801|Clostridia,25U0S@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_118	1476973.JMMB01000007_gene905	5.983e-84	280.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,25RHY@186804|Peptostreptococcaceae	186801|Clostridia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
HKD1_k127_5849793_87	1476973.JMMB01000007_gene906	3.657e-132	424.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia,25QX2@186804|Peptostreptococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HKD1_k127_5849793_139	500633.CLOHIR_01117	2.693e-53	191.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,25RJB@186804|Peptostreptococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HKD1_k127_5849793_49	1476973.JMMB01000007_gene908	1.205e-186	584.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,25QI5@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HKD1_k127_5849793_110	1476973.JMMB01000007_gene909	3.286e-97	319.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,25RCD@186804|Peptostreptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
HKD1_k127_5849793_31	1476973.JMMB01000007_gene910	7.033e-226	704.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25R2I@186804|Peptostreptococcaceae	186801|Clostridia	F	Permease family	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
HKD1_k127_5849793_10	1476973.JMMB01000007_gene912	0.0	1043.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,25QWG@186804|Peptostreptococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HKD1_k127_5849793_58	1476973.JMMB01000007_gene913	2.54e-171	540.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25QT7@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HKD1_k127_5849793_94	1476973.JMMB01000007_gene914	1.732e-123	396.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,25QET@186804|Peptostreptococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HKD1_k127_5849793_143	1476973.JMMB01000007_gene915	1.704e-42	156.0	COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,25JAW@186801|Clostridia,25RST@186804|Peptostreptococcaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
HKD1_k127_5849793_28	1476973.JMMB01000007_gene916	4.965e-235	729.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25QR8@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HKD1_k127_5849793_4	1476973.JMMB01000007_gene917	0.0	1502.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25QCV@186804|Peptostreptococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HKD1_k127_5849793_122	1476973.JMMB01000007_gene918	1.436e-79	267.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,25RD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD1_k127_5849793_48	1476973.JMMB01000007_gene919	1.183e-186	586.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,25QKZ@186804|Peptostreptococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HKD1_k127_5849793_97	1476973.JMMB01000007_gene920	8.04e-122	394.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,24G2F@186801|Clostridia,25T5B@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
HKD1_k127_5849793_95	1301100.HG529232_gene7468	4.297e-122	395.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,36FA7@31979|Clostridiaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HKD1_k127_5849793_18	1476973.JMMB01000007_gene922	2.679e-270	834.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,25QCI@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HKD1_k127_5849793_42	1301100.HG529232_gene7470	1.115e-200	627.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,36E1B@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HKD1_k127_5849793_84	1476973.JMMB01000007_gene924	3.862e-134	430.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,25R6H@186804|Peptostreptococcaceae	186801|Clostridia	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HKD1_k127_5849793_20	1476973.JMMB01000007_gene925	4.562e-263	820.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25QJS@186804|Peptostreptococcaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HKD1_k127_5849793_63	1476973.JMMB01000007_gene926	3.077e-168	530.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,25QPZ@186804|Peptostreptococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HKD1_k127_5849793_93	1476973.JMMB01000007_gene927	3.086e-125	402.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25R34@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HKD1_k127_5849793_101	1476973.JMMB01000007_gene928	2.214e-116	376.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,25RB0@186804|Peptostreptococcaceae	186801|Clostridia	H	thiamine	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
HKD1_k127_5849793_120	1476973.JMMB01000007_gene929	1.041e-81	274.0	COG4635@1|root,COG4635@2|Bacteria,1V6RV@1239|Firmicutes,24N9M@186801|Clostridia,25RV0@186804|Peptostreptococcaceae	186801|Clostridia	CH	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
HKD1_k127_5849793_155	1301100.HG529233_gene7347	8.91e-19	87.0	2CHF6@1|root,32M7S@2|Bacteria,1W62Y@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_148	1476973.JMMB01000007_gene931	1.451e-33	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,25RTD@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HKD1_k127_5849793_137	1476973.JMMB01000007_gene932	6.064e-59	206.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,25RQH@186804|Peptostreptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD1_k127_5849793_12	1476973.JMMB01000007_gene933	3.595e-311	957.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,25QKG@186804|Peptostreptococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HKD1_k127_5849793_6	1476973.JMMB01000007_gene934	0.0	1250.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,25QY1@186804|Peptostreptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HKD1_k127_5849793_107	1476973.JMMB01000007_gene935	1.613e-98	323.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,25RB7@186804|Peptostreptococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HKD1_k127_5849793_112	1476973.JMMB01000007_gene936	3.194e-96	316.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,25RFI@186804|Peptostreptococcaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HKD1_k127_5849793_116	1476973.JMMB01000007_gene937	2.741e-89	296.0	COG1193@1|root,COG1193@2|Bacteria,1UJ73@1239|Firmicutes,24Y0J@186801|Clostridia,25RQJ@186804|Peptostreptococcaceae	186801|Clostridia	L	negative regulation of DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_40	1476973.JMMB01000007_gene938	3.109e-205	644.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,25S9M@186804|Peptostreptococcaceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HKD1_k127_5849793_99	1476973.JMMB01000007_gene939	4.413e-120	389.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25RBA@186804|Peptostreptococcaceae	186801|Clostridia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HKD1_k127_5849793_19	1476973.JMMB01000007_gene940	2.519e-264	821.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25QT6@186804|Peptostreptococcaceae	186801|Clostridia	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HKD1_k127_5849793_26	1476973.JMMB01000007_gene941	2.067e-240	747.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25R07@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
HKD1_k127_5849793_74	1476973.JMMB01000007_gene942	3.586e-155	491.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25SIA@186804|Peptostreptococcaceae	186801|Clostridia	C	Electron transfer flavoprotein domain	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD1_k127_5849793_23	1476973.JMMB01000007_gene943	3.204e-242	750.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25QKB@186804|Peptostreptococcaceae	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
HKD1_k127_5849793_16	1476973.JMMB01000007_gene944	1.291e-281	869.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,25SG3@186804|Peptostreptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	glcD1	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HKD1_k127_5849793_29	1476973.JMMB01000007_gene945	7.206e-233	725.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,25QMM@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HKD1_k127_5849793_24	1476973.JMMB01000007_gene946	1.411e-241	748.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,25QRI@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HKD1_k127_5849793_109	1476973.JMMB01000007_gene947	6.178e-98	321.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,25RES@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HKD1_k127_5849793_150	1476973.JMMB01000007_gene948	3.535e-32	124.0	COG0333@1|root,COG0333@2|Bacteria,1UG2S@1239|Firmicutes,25N84@186801|Clostridia,25RTX@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HKD1_k127_5849793_104	1476973.JMMB01000007_gene949	1.374e-101	332.0	COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,24JY2@186801|Clostridia,25S4Z@186804|Peptostreptococcaceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	fapR	-	-	-	-	-	-	-	-	-	-	-	4HBT,HTH_DeoR
HKD1_k127_5849793_45	1476973.JMMB01000007_gene950	2.883e-189	594.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,25QM2@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HKD1_k127_5849793_73	1391646.AVSU01000032_gene2328	9.885e-158	503.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,25R9C@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HKD1_k127_5849793_50	1476973.JMMB01000007_gene952	3.778e-182	571.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,25R0F@186804|Peptostreptococcaceae	186801|Clostridia	S	enoyl- acyl-carrier-protein reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
HKD1_k127_5849793_59	1476973.JMMB01000007_gene953	5.523e-170	537.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25RFG@186804|Peptostreptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HKD1_k127_5849793_80	1476973.JMMB01000007_gene954	2.384e-142	454.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25R8Y@186804|Peptostreptococcaceae	186801|Clostridia	IQ	3-oxoacyl- acyl-carrier-protein reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HKD1_k127_5849793_149	272563.CD630_11830	1.282e-32	127.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,25RUU@186804|Peptostreptococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HKD1_k127_5849793_21	1476973.JMMB01000007_gene956	6.162e-249	770.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,25QQD@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HKD1_k127_5849793_46	1476973.JMMB01000007_gene957	1.651e-188	591.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,25R76@186804|Peptostreptococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
HKD1_k127_5849793_136	1151292.QEW_1571	2.639e-60	213.0	2CEWW@1|root,30FPA@2|Bacteria,1UEC0@1239|Firmicutes,25J7U@186801|Clostridia,25RD4@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AB (spore_III_AB)	spoIIIAB	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
HKD1_k127_5849793_151	1476973.JMMB01000007_gene959	6.501e-32	124.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,25RWF@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AC/AD protein family	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD1_k127_5849793_132	1476973.JMMB01000007_gene960	6.354e-65	223.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,25TEC@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AC/AD protein family	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HKD1_k127_5849793_41	1476973.JMMB01000007_gene961	9.726e-202	633.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,25QH9@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AE (spore_III_AE)	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HKD1_k127_5849793_115	1476973.JMMB01000007_gene962	5.342e-90	299.0	2EW5V@1|root,33PIY@2|Bacteria,1VR31@1239|Firmicutes,25J9I@186801|Clostridia,25RKM@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	spoiIIIAF	-	-	ko:K06395	-	-	-	-	ko00000	-	-	-	Spore_III_AF
HKD1_k127_5849793_125	1476973.JMMB01000007_gene963	8.784e-75	254.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,25RHN@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_5849793_108	1476973.JMMB01000007_gene964	4.519e-98	324.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,25RG9@186804|Peptostreptococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HKD1_k127_5849793_131	1476973.JMMB01000007_gene965	1.35e-65	225.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,25RIH@186804|Peptostreptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
HKD1_k127_5849793_154	1219626.HMPREF1639_08920	1.968e-21	101.0	COG0781@1|root,COG0781@2|Bacteria	2|Bacteria	J	transcription antitermination	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HKD1_k127_5849793_70	1301100.HG529233_gene7384	1.007e-159	508.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,36IKM@31979|Clostridiaceae	186801|Clostridia	O	Glycoprotease family	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HKD1_k127_5849793_33	1301100.HG529233_gene7385	1.009e-221	691.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,36EU5@31979|Clostridiaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HKD1_k127_5849793_152	1301100.HG529233_gene7386	1.983e-30	121.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes	1239|Firmicutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HKD1_k127_5849793_64	1476973.JMMB01000007_gene970	3.671e-166	525.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,25QKP@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
HKD1_k127_5849793_127	1301100.HG529233_gene7388	3.703e-72	245.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,36KSA@31979|Clostridiaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
HKD1_k127_5849793_8	1476973.JMMB01000007_gene972	0.0	1131.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25QT2@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HKD1_k127_5849793_67	1476973.JMMB01000007_gene973	2.78e-161	510.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,25QI7@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HKD1_k127_5849793_11	1476973.JMMB01000007_gene974	9.256e-315	969.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,25QYR@186804|Peptostreptococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HKD1_k127_5849793_66	1476973.JMMB01000007_gene975	1.99e-165	526.0	COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,24AFA@186801|Clostridia,25RH5@186804|Peptostreptococcaceae	186801|Clostridia	M	SpoIVB peptidase S55	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
HKD1_k127_5849793_56	1476973.JMMB01000007_gene976	8.864e-174	546.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia,25R5I@186804|Peptostreptococcaceae	186801|Clostridia	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
HKD1_k127_5849793_47	1476973.JMMB01000007_gene977	2.476e-188	597.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,25SBM@186804|Peptostreptococcaceae	186801|Clostridia	H	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HKD1_k127_5849793_34	1476973.JMMB01000007_gene978	1.057e-219	683.0	COG4825@1|root,COG4825@2|Bacteria,1TQ8Q@1239|Firmicutes,24B4X@186801|Clostridia,25QZP@186804|Peptostreptococcaceae	186801|Clostridia	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,TPPK_C
HKD1_k127_5849793_82	1476973.JMMB01000007_gene979	3.568e-138	444.0	28JWD@1|root,2Z9M5@2|Bacteria,1UZF1@1239|Firmicutes,24HZN@186801|Clostridia,25T02@186804|Peptostreptococcaceae	186801|Clostridia	S	Copper transport outer membrane protein, MctB	-	-	-	-	-	-	-	-	-	-	-	-	MctB
HKD1_k127_5849793_85	1476973.JMMB01000007_gene980	1.059e-133	427.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,25KCB@186801|Clostridia,25QQF@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HKD1_k127_5849793_76	1476973.JMMB01000007_gene981	6.363e-152	482.0	COG0472@1|root,COG0472@2|Bacteria,1V7C4@1239|Firmicutes,24K6E@186801|Clostridia,25R28@186804|Peptostreptococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
HKD1_k127_5849793_37	1476973.JMMB01000007_gene982	9.899e-212	660.0	COG3502@1|root,COG3502@2|Bacteria,1TQW1@1239|Firmicutes,24952@186801|Clostridia,25R2G@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
HKD1_k127_5849793_147	1121087.AUCK01000001_gene3045	1.238e-33	136.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus	91061|Bacilli	L	Belongs to the Nudix hydrolase family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
HKD1_k127_5849793_111	1476973.JMMB01000007_gene984	1.796e-96	318.0	2F26K@1|root,33V4V@2|Bacteria,1VUM8@1239|Firmicutes,24Y8R@186801|Clostridia,25RRY@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	ko:K06384	-	-	-	-	ko00000	-	-	-	SpoIIM
HKD1_k127_5849793_69	1476973.JMMB01000007_gene985	1.959e-160	508.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,25QDH@186804|Peptostreptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HKD1_k127_5849793_30	1476973.JMMB01000007_gene986	1.086e-231	719.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,25QPX@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
HKD1_k127_5849793_72	1476973.JMMB01000007_gene987	4.679e-159	503.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,25S30@186804|Peptostreptococcaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_5849793_22	1301100.HG529233_gene7409	6.451e-246	763.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,36DHU@31979|Clostridiaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HKD1_k127_5849793_54	1476973.JMMB01000007_gene989	5.382e-176	556.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25QDY@186804|Peptostreptococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HKD1_k127_5849793_103	1408823.AXUS01000005_gene2594	7.552e-108	352.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,25ST0@186804|Peptostreptococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
HKD1_k127_5849793_65	1476973.JMMB01000007_gene991	5.067e-166	525.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25QJC@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HKD1_k127_5849793_98	1476973.JMMB01000007_gene992	2.055e-120	388.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,25RDB@186804|Peptostreptococcaceae	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HKD1_k127_5849793_15	1476973.JMMB01000007_gene993	3.111e-286	887.0	COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,25CAC@186801|Clostridia,25QG0@186804|Peptostreptococcaceae	186801|Clostridia	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD1_k127_5849793_96	1476973.JMMB01000007_gene994	4.353e-122	393.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,25R4Q@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HKD1_k127_5849793_9	1476973.JMMB01000007_gene995	0.0	1070.0	COG0642@1|root,COG2205@2|Bacteria,1VS39@1239|Firmicutes,24XJK@186801|Clostridia,25R9T@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
HKD1_k127_5849793_25	1476973.JMMB01000007_gene996	1.441e-240	768.0	COG0642@1|root,COG2205@2|Bacteria,1UVPB@1239|Firmicutes,24YXG@186801|Clostridia,25T4B@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_117	1476973.JMMB01000007_gene997	6.678e-85	311.0	COG0642@1|root,COG2205@2|Bacteria	1476973.JMMB01000007_gene997|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_77	1476973.JMMB01000007_gene998	2.153e-149	476.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25S82@186804|Peptostreptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HKD1_k127_5849793_134	1476973.JMMB01000007_gene1000	2.486e-63	223.0	2FBI0@1|root,343PA@2|Bacteria,1W17X@1239|Firmicutes,251XV@186801|Clostridia,25S09@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_128	1476973.JMMB01000007_gene1002	4.41e-72	247.0	2F8V7@1|root,34175@2|Bacteria,1VXG1@1239|Firmicutes,250UQ@186801|Clostridia,25RU4@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_130	1476973.JMMB01000007_gene1003	2.621e-68	235.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,25S01@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HKD1_k127_5849793_102	1476973.JMMB01000007_gene1006	4.83e-115	372.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25QK6@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HKD1_k127_5849793_126	1476973.JMMB01000007_gene1007	1.013e-72	247.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24SIH@186801|Clostridia,25RW2@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_88	1476973.JMMB01000007_gene1008	9.576e-131	419.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,25QZ3@186804|Peptostreptococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HKD1_k127_5849793_38	1476973.JMMB01000007_gene1009	6.752e-211	657.0	COG1243@1|root,COG1243@2|Bacteria,1TS1F@1239|Firmicutes,248YV@186801|Clostridia,25QV2@186804|Peptostreptococcaceae	186801|Clostridia	BK	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,Radical_SAM_C
HKD1_k127_5849793_1	1476973.JMMB01000007_gene1010	0.0	1825.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25QTR@186804|Peptostreptococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HKD1_k127_5849793_53	1476973.JMMB01000007_gene1011	8.461e-180	573.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25R1C@186804|Peptostreptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HKD1_k127_5849793_133	1301100.HG529233_gene7433	1.395e-64	222.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,36MJ0@31979|Clostridiaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HKD1_k127_5849793_17	1301100.HG529233_gene7434	7.357e-272	839.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,36E8W@31979|Clostridiaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HKD1_k127_5849793_140	1301100.HG529233_gene7435	4.132e-52	184.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,36KP2@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HKD1_k127_5849793_146	1301100.HG529233_gene7436	9.015e-34	131.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,36KGX@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HKD1_k127_5849793_113	1476973.JMMB01000007_gene1016	6.516e-92	303.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,25RDF@186804|Peptostreptococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HKD1_k127_5849793_83	1476973.JMMB01000007_gene1017	6.001e-136	434.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,25QFE@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HKD1_k127_5849793_129	1476973.JMMB01000007_gene1018	7.221e-69	234.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25RM0@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HKD1_k127_5849793_156	1301100.HG529234_gene7332	2.591e-15	76.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia,36E6K@31979|Clostridiaceae	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	-	-	-	-	-	-	-	-	-	-	-	-	PMI_typeI
HKD1_k127_5849793_51	1476973.JMMB01000007_gene1020	2.189e-180	567.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,25QQP@186804|Peptostreptococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HKD1_k127_5849793_61	1410653.JHVC01000001_gene1870	1.641e-169	537.0	COG1775@1|root,COG1775@2|Bacteria,1TSHM@1239|Firmicutes,249WE@186801|Clostridia,36EPN@31979|Clostridiaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HKD1_k127_5849793_86	536227.CcarbDRAFT_2552	1.149e-133	429.0	COG1924@1|root,COG1924@2|Bacteria,1TQWR@1239|Firmicutes,2484G@186801|Clostridia,36DUS@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	fldI1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HKD1_k127_5849793_145	1410653.JHVC01000001_gene1868	7.61e-36	137.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,36JJD@31979|Clostridiaceae	186801|Clostridia	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD1_k127_5849793_153	1487921.DP68_16780	3.063e-30	120.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,36JJD@31979|Clostridiaceae	186801|Clostridia	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HKD1_k127_5849793_105	386415.NT01CX_2385	8.651e-101	332.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,36HKB@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HKD1_k127_5849793_106	1487921.DP68_16770	1.595e-100	330.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,36DD1@31979|Clostridiaceae	186801|Clostridia	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HKD1_k127_5849793_90	536227.CcarbDRAFT_2549	5.641e-129	413.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,36DMD@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
HKD1_k127_5849793_55	1487921.DP68_18470	1.455e-174	556.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,36E48@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HKD1_k127_5849793_75	1410653.JHVC01000020_gene4572	2.135e-153	491.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,36E3S@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HKD1_k127_5849793_92	1286171.EAL2_c12120	2.885e-125	407.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,25UYD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HKD1_k127_5849793_52	1511.CLOST_0927	6.024e-180	567.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25SFG@186804|Peptostreptococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
HKD1_k127_5849793_57	1487921.DP68_18455	4.496e-172	547.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,36DPQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_5849793_62	1262449.CP6013_1826	1.707e-168	535.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,36DTQ@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD1_k127_5849793_2	1128398.Curi_c23250	0.0	1585.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,2681X@186813|unclassified Clostridiales	186801|Clostridia	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD1_k127_5849793_141	1476973.JMMB01000007_gene1021	2.454e-49	177.0	2BDS8@1|root,327FZ@2|Bacteria,1UTC2@1239|Firmicutes,252C2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_157	883110.HMPREF9260_01349	0.0004171	51.0	COG1196@1|root,COG1196@2|Bacteria,1TQJD@1239|Firmicutes,4I62H@91061|Bacilli,27EF3@186827|Aerococcaceae	91061|Bacilli	D	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
HKD1_k127_5849793_32	1476973.JMMB01000007_gene1025	1.453e-225	704.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,25QIF@186804|Peptostreptococcaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	brnQ-2	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
HKD1_k127_5849793_78	1301100.HG529235_gene7311	1.011e-146	467.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,36DHX@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HKD1_k127_5849793_43	1476973.JMMB01000007_gene1027	2.59e-196	616.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,25QMN@186804|Peptostreptococcaceae	186801|Clostridia	C	dehydrogenase (FMN-dependent)	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
HKD1_k127_5849793_60	1301100.HG529235_gene7321	5.688e-170	543.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,36WWA@31979|Clostridiaceae	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HKD1_k127_5849793_138	1476973.JMMB01000007_gene1028	1.387e-57	201.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,25RU7@186804|Peptostreptococcaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HKD1_k127_5849793_13	1476973.JMMB01000007_gene1029	9.132e-296	912.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25QJ8@186804|Peptostreptococcaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HKD1_k127_5849793_44	1476973.JMMB01000007_gene1030	4.409e-195	612.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,25QU9@186804|Peptostreptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HKD1_k127_5849793_5	1476973.JMMB01000007_gene1031	0.0	1270.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,25R1U@186804|Peptostreptococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HKD1_k127_5849793_81	1476973.JMMB01000007_gene1032	2.497e-142	454.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25QEE@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
HKD1_k127_5849793_36	1151292.QEW_1653	1.784e-218	683.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,25R4V@186804|Peptostreptococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HKD1_k127_5849793_89	1476973.JMMB01000007_gene1034	1.352e-130	420.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,24M7G@186801|Clostridia,25RBM@186804|Peptostreptococcaceae	186801|Clostridia	S	GNAT acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	GNAT_acetyltran
HKD1_k127_5849793_68	1476973.JMMB01000007_gene1035	3.916e-161	511.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,25QYP@186804|Peptostreptococcaceae	186801|Clostridia	G	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HKD1_k127_5849793_124	1476973.JMMB01000007_gene1036	2.315e-78	263.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25RD2@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HKD1_k127_5849793_27	1476973.JMMB01000007_gene1037	1e-237	737.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25R1G@186804|Peptostreptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HKD1_k127_5849793_121	1292035.H476_1732	6.322e-81	271.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25RDC@186804|Peptostreptococcaceae	186801|Clostridia	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HKD1_k127_5849793_35	1476973.JMMB01000007_gene1039	1.794e-219	682.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,25QIE@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HKD1_k127_5849793_3	1476973.JMMB01000007_gene1040	0.0	1581.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25QTB@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HKD1_k127_5849793_142	1476973.JMMB01000007_gene1041	5.987e-43	158.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,25RQS@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HKD1_k127_5849793_7	1476973.JMMB01000007_gene1042	0.0	1168.0	COG3119@1|root,COG3119@2|Bacteria,1TSMM@1239|Firmicutes,247YU@186801|Clostridia,25QS7@186804|Peptostreptococcaceae	186801|Clostridia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5849793_123	1301100.HG529236_gene7247	1.852e-79	266.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,36IV4@31979|Clostridiaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HKD1_k127_5875391_14	332101.JIBU02000005_gene404	2.51e-77	260.0	COG4565@1|root,COG4565@2|Bacteria,1V49R@1239|Firmicutes,24BJS@186801|Clostridia,36HG7@31979|Clostridiaceae	186801|Clostridia	KT	transcriptional regulatory protein	-	-	-	ko:K02475,ko:K11615,ko:K11692,ko:K11712	ko02020,map02020	M00489,M00490	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_11,HTH_IclR,Response_reg
HKD1_k127_5875391_4	1476973.JMMB01000007_gene1418	1.73e-163	516.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25RJQ@186804|Peptostreptococcaceae	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_5875391_10	318464.IO99_05850	6.084e-93	307.0	COG3542@1|root,COG3542@2|Bacteria,1V4QS@1239|Firmicutes,25DUY@186801|Clostridia	186801|Clostridia	S	Cupin superfamily (DUF985)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_5
HKD1_k127_5875391_9	1476973.JMMB01000007_gene1395	3.051e-94	310.0	COG2032@1|root,COG2032@2|Bacteria,1V3HM@1239|Firmicutes,24HGH@186801|Clostridia,25RFX@186804|Peptostreptococcaceae	186801|Clostridia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
HKD1_k127_5875391_11	1301100.HG529417_gene2990	3.351e-88	296.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	3.5.1.28	ko:K01447,ko:K21471	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
HKD1_k127_5875391_18	1227349.C170_29518	1.943e-16	79.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,26QRQ@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HKD1_k127_5875391_23	1122216.AUHW01000002_gene1788	8.969e-07	51.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H4FG@909932|Negativicutes	909932|Negativicutes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_5875391_0	1415774.U728_177	1.617e-230	734.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,Response_reg
HKD1_k127_5875391_12	929506.CbC4_1708	2.345e-83	279.0	COG0454@1|root,COG0456@2|Bacteria,1VC3M@1239|Firmicutes,25AZ4@186801|Clostridia,36I9H@31979|Clostridiaceae	186801|Clostridia	K	acetyltransferase, GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_5875391_26	545697.HMPREF0216_00280	3.356e-06	49.0	COG3677@1|root,COG3677@2|Bacteria,1UM1N@1239|Firmicutes,25G8R@186801|Clostridia,36V28@31979|Clostridiaceae	186801|Clostridia	L	InsA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_Tnp_IS1
HKD1_k127_5875391_7	748727.CLJU_c24350	1.579e-126	409.0	COG1600@1|root,COG1600@2|Bacteria,1V6AI@1239|Firmicutes,24HW4@186801|Clostridia,36QXA@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
HKD1_k127_5875391_22	536233.CLO_1638	6.939e-09	58.0	2DRCK@1|root,33B85@2|Bacteria,1VMHG@1239|Firmicutes,24S3G@186801|Clostridia,36MMQ@31979|Clostridiaceae	186801|Clostridia	S	Ribosomal protein L7/L12 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L12
HKD1_k127_5875391_5	338966.Ppro_2997	7.152e-163	547.0	COG3322@1|root,COG5001@1|root,COG3322@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43U61@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
HKD1_k127_5875391_1	1476973.JMMB01000007_gene1426	2.919e-218	682.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,25NTF@186801|Clostridia,25SB3@186804|Peptostreptococcaceae	186801|Clostridia	EGP	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
HKD1_k127_5875391_19	1391646.AVSU01000037_gene2043	5.846e-16	79.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,25TCP@186804|Peptostreptococcaceae	186801|Clostridia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
HKD1_k127_5875391_25	1476973.JMMB01000007_gene1426	2.725e-06	49.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,25NTF@186801|Clostridia,25SB3@186804|Peptostreptococcaceae	186801|Clostridia	EGP	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
HKD1_k127_5875391_27	272563.CD630_11200	4.098e-05	46.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R3V@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HKD1_k127_5875391_24	445973.CLOBAR_02594	1.602e-06	51.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R3V@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyruvate formate lyase-like	-	-	4.3.99.4	ko:K20038	-	-	-	-	ko00000,ko01000	-	-	-	Gly_radical,PFL-like
HKD1_k127_5875391_2	573061.Clocel_2091	3.387e-200	630.0	COG0004@1|root,COG0004@2|Bacteria,1UQ75@1239|Firmicutes,257WC@186801|Clostridia,36G6V@31979|Clostridiaceae	186801|Clostridia	P	Ammonium Transporter	-	-	-	ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11.4	-	-	Ammonium_transp
HKD1_k127_5875391_17	931276.Cspa_c29680	1.88e-17	84.0	COG1251@1|root,COG1251@2|Bacteria,1UJA3@1239|Firmicutes,24UK3@186801|Clostridia,36NRQ@31979|Clostridiaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
HKD1_k127_5875391_6	1476973.JMMB01000007_gene1382	1.465e-131	431.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25SDU@186804|Peptostreptococcaceae	186801|Clostridia	S	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
HKD1_k127_5875391_8	1476973.JMMB01000007_gene1629	3.365e-107	349.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25U5T@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3B	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD1_k127_5875391_13	1476973.JMMB01000007_gene2145	3.237e-82	281.0	COG5522@1|root,COG5522@2|Bacteria,1VCFM@1239|Firmicutes,24PK8@186801|Clostridia,25RAI@186804|Peptostreptococcaceae	186801|Clostridia	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
HKD1_k127_5875391_16	86416.Clopa_2111	2.917e-72	246.0	28NQ2@1|root,2ZBPT@2|Bacteria,1V2UY@1239|Firmicutes,24JMI@186801|Clostridia,36J1Z@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5875391_21	1195236.CTER_1143	6.051e-09	59.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,24QSV@186801|Clostridia,3WKIG@541000|Ruminococcaceae	186801|Clostridia	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD1_k127_5875391_15	1476973.JMMB01000007_gene1446	9.949e-75	252.0	COG1607@1|root,COG1607@2|Bacteria,1VD4Z@1239|Firmicutes,24JWI@186801|Clostridia,25TFR@186804|Peptostreptococcaceae	186801|Clostridia	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
HKD1_k127_5875391_3	1476973.JMMB01000007_gene293	2.304e-187	590.0	COG1649@1|root,COG1649@2|Bacteria,1UXBI@1239|Firmicutes,25005@186801|Clostridia,25SFN@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
HKD1_k127_5878006_7	1476973.JMMB01000007_gene1454	2.504e-179	571.0	COG0699@1|root,COG0699@2|Bacteria,1UEI4@1239|Firmicutes,24ZFS@186801|Clostridia,25SB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD1_k127_5878006_9	1301100.HG529343_gene2444	7.294e-173	544.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,36E45@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HKD1_k127_5878006_20	1476973.JMMB01000007_gene1451	6.093e-96	315.0	2DV8V@1|root,33UR2@2|Bacteria,1VUF4@1239|Firmicutes,24ZB8@186801|Clostridia,25RX9@186804|Peptostreptococcaceae	186801|Clostridia	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HSDR_N_2
HKD1_k127_5878006_8	1476973.JMMB01000007_gene1447	2.112e-177	561.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,25SC1@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HKD1_k127_5878006_4	1476973.JMMB01000007_gene1440	2.255e-200	631.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,25SHV@186804|Peptostreptococcaceae	186801|Clostridia	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HKD1_k127_5878006_21	1476973.JMMB01000007_gene1439	3.862e-89	297.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,25TG3@186804|Peptostreptococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HKD1_k127_5878006_16	1476973.JMMB01000007_gene1438	7.066e-113	366.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,25SA4@186804|Peptostreptococcaceae	186801|Clostridia	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD1_k127_5878006_12	1391646.AVSU01000038_gene1956	2.338e-136	438.0	COG1307@1|root,COG1307@2|Bacteria,1UXBG@1239|Firmicutes,25KZA@186801|Clostridia,25SS0@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_5878006_29	1476973.JMMB01000007_gene1619	1.576e-33	130.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_5878006_15	272563.CD630_23700	3.438e-117	383.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,25QRQ@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
HKD1_k127_5878006_5	1196322.A370_05828	3.027e-194	614.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,36EIS@31979|Clostridiaceae	186801|Clostridia	H	L-aspartate oxidase	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HKD1_k127_5878006_11	1151292.QEW_2910	1.315e-148	475.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,25R9M@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
HKD1_k127_5878006_13	272563.CD630_14910	7.847e-124	401.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,25QQA@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HKD1_k127_5878006_19	272563.CD630_14900	2.992e-98	326.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,25QKR@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HKD1_k127_5878006_10	1301100.HG529344_gene3195	6.318e-169	535.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,36DVA@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HKD1_k127_5878006_26	1476973.JMMB01000007_gene1347	4.547e-61	216.0	2CDGN@1|root,33XE2@2|Bacteria,1VVF2@1239|Firmicutes,250P1@186801|Clostridia,25RVN@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5878006_24	1151292.QEW_1892	8.315e-73	250.0	2BYWB@1|root,331N7@2|Bacteria,1VC73@1239|Firmicutes,24NV6@186801|Clostridia,25RKX@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
HKD1_k127_5878006_0	1301100.HG529344_gene3207	0.0	1166.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,36EFP@31979|Clostridiaceae	186801|Clostridia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
HKD1_k127_5878006_28	1476973.JMMB01000007_gene1346	4.529e-36	138.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,25N5S@186801|Clostridia,25TXA@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_5878006_23	1476973.JMMB01000007_gene848	4.534e-86	291.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,25SIK@186804|Peptostreptococcaceae	186801|Clostridia	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HKD1_k127_5878006_22	1476973.JMMB01000007_gene1343	5.844e-89	297.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,25TKY@186804|Peptostreptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HKD1_k127_5878006_1	1476973.JMMB01000007_gene1342	3.795e-317	975.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,25T11@186804|Peptostreptococcaceae	186801|Clostridia	C	Molydopterin dinucleotide binding domain	fdhA	-	1.17.1.10,1.17.1.11,1.17.1.9	ko:K00123,ko:K05299,ko:K22341	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HKD1_k127_5878006_3	1476973.JMMB01000007_gene1341	1.404e-212	662.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia	186801|Clostridia	C	Molybdopterin oxidoreductase, Fe4S4	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HKD1_k127_5878006_25	445335.CBN_2014	1.261e-66	237.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,36ERE@31979|Clostridiaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
HKD1_k127_5878006_30	1540257.JQMW01000010_gene1329	3.423e-29	125.0	COG3839@1|root,COG3839@2|Bacteria,1UJBK@1239|Firmicutes,25F0X@186801|Clostridia,36I6M@31979|Clostridiaceae	186801|Clostridia	G	PFAM ABC transporter related	tupC	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
HKD1_k127_5878006_27	1540257.JQMW01000014_gene57	8.2e-48	179.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia,36IMF@31979|Clostridiaceae	186801|Clostridia	P	inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
HKD1_k127_5878006_14	1151292.QEW_1291	7.659e-120	392.0	COG1910@1|root,COG3311@1|root,COG1910@2|Bacteria,COG3311@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,25S4R@186804|Peptostreptococcaceae	186801|Clostridia	P	Helix-turn-helix domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
HKD1_k127_5878006_2	445335.CBN_2009	4.984e-218	693.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,36GB8@31979|Clostridiaceae	186801|Clostridia	P	DNA binding domain, excisionase family	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
HKD1_k127_5878006_17	857293.CAAU_0406	7.198e-111	373.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,36E4B@31979|Clostridiaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HKD1_k127_5878006_6	1476973.JMMB01000007_gene1339	3.203e-187	593.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25QIR@186804|Peptostreptococcaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HKD1_k127_5878006_18	1476973.JMMB01000007_gene1338	2.257e-103	339.0	COG3568@1|root,COG3568@2|Bacteria,1VVUM@1239|Firmicutes,250G8@186801|Clostridia,25RJC@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
HKD1_k127_5878006_32	1301100.HG529275_gene1611	3.825e-20	90.0	29IBE@1|root,2ZRFU@2|Bacteria,1W52P@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5924886_2	1443125.Z962_p0079	6.411e-106	361.0	COG0433@1|root,COG0433@2|Bacteria,1V4Z4@1239|Firmicutes,24E9I@186801|Clostridia,36GXR@31979|Clostridiaceae	186801|Clostridia	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5924886_0	1476973.JMMB01000007_gene1506	0.0	1066.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,25QUQ@186804|Peptostreptococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HKD1_k127_5924886_3	1476973.JMMB01000007_gene1507	1.037e-80	274.0	2DJ8S@1|root,304ZY@2|Bacteria,1UEDJ@1239|Firmicutes,2519S@186801|Clostridia,25TS9@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_5924886_4	1476973.JMMB01000007_gene1508	2.073e-66	231.0	COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,25CNM@186801|Clostridia,25RRE@186804|Peptostreptococcaceae	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
HKD1_k127_5924886_1	1476973.JMMB01000007_gene1509	2.659e-106	346.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia,25SY0@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6097753_13	1301100.HG529309_gene403	4.859e-41	154.0	2BSIP@1|root,32MKZ@2|Bacteria,1UTTM@1239|Firmicutes,2549T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6097753_3	1301100.HG529268_gene608	4.483e-201	632.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
HKD1_k127_6097753_4	1476973.JMMB01000007_gene1474	2.305e-187	591.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,25QXE@186804|Peptostreptococcaceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
HKD1_k127_6097753_2	1301100.HG529395_gene6868	9.372e-207	657.0	COG1145@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24BF5@186801|Clostridia,36E2Y@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_7,PAS
HKD1_k127_6097753_14	1476973.JMMB01000007_gene1472	4.84e-29	117.0	COG1905@1|root,COG1905@2|Bacteria,1VFEK@1239|Firmicutes,24QMM@186801|Clostridia	186801|Clostridia	C	NADH ubiquinone oxidoreductase 24 kD subunit	fhmD	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
HKD1_k127_6097753_11	1301100.HG529262_gene717	6.378e-89	298.0	COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,24JVZ@186801|Clostridia,36I59@31979|Clostridiaceae	186801|Clostridia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
HKD1_k127_6097753_9	1476973.JMMB01000007_gene2310	5.117e-109	357.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia,25SZ4@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6097753_12	1151292.QEW_1067	7.207e-63	219.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_6097753_16	1292035.H476_2856	6.871e-19	88.0	2BEIU@1|root,328A4@2|Bacteria,1UU7H@1239|Firmicutes,255SM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6097753_1	632245.CLP_2370	1.176e-212	665.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,36DPQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HKD1_k127_6097753_5	632245.CLP_2374	2.981e-185	589.0	COG0833@1|root,COG0833@2|Bacteria,1UHPU@1239|Firmicutes,25E64@186801|Clostridia,36UUC@31979|Clostridiaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD1_k127_6097753_8	1321784.HMPREF1987_01263	6.434e-137	449.0	COG0591@1|root,COG0591@2|Bacteria,1TQEZ@1239|Firmicutes,24AJN@186801|Clostridia,25T2R@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
HKD1_k127_6097753_7	1304284.L21TH_2281	2.364e-143	463.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EGP@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
HKD1_k127_6097753_10	1286171.EAL2_c18430	1.007e-106	354.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25W5P@186806|Eubacteriaceae	186801|Clostridia	C	Phosphate acetyl/butaryl transferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
HKD1_k127_6097753_6	1321784.HMPREF1987_01259	2.665e-181	577.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,25T1T@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	sucD	-	1.2.1.76,1.2.1.87	ko:K13922,ko:K18119	ko00640,ko00650,ko01100,ko01200,map00640,map00650,map01100,map01200	-	R09097,R09280	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
HKD1_k127_6097753_15	1476973.JMMB01000007_gene1998	2.344e-28	114.0	2BEAK@1|root,3281K@2|Bacteria,1UTYR@1239|Firmicutes,254VW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6097753_0	1476973.JMMB01000007_gene2502	0.0	1447.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25QYJ@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD1_k127_6184409_0	1444310.JANV01000205_gene621	1.023e-175	561.0	28N83@1|root,2ZBCM@2|Bacteria,1TT4T@1239|Firmicutes,4HTS9@91061|Bacilli,1ZEBG@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RdRP
HKD1_k127_619907_0	931276.Cspa_c50420	1.385e-133	427.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,36DTC@31979|Clostridiaceae	186801|Clostridia	C	malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HKD1_k127_619907_9	1301100.HG529241_gene7165	8.294e-12	65.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia,36I6X@31979|Clostridiaceae	186801|Clostridia	J	GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
HKD1_k127_619907_2	588581.Cpap_3750	2.871e-47	172.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24KBG@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD1_k127_619907_5	1304866.K413DRAFT_1420	6.967e-37	143.0	COG5015@1|root,COG5015@2|Bacteria,1V43Y@1239|Firmicutes,24HQB@186801|Clostridia,36U56@31979|Clostridiaceae	186801|Clostridia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
HKD1_k127_619907_10	1408823.AXUS01000009_gene1962	8.89e-09	58.0	COG0655@1|root,COG0655@2|Bacteria,1V5KZ@1239|Firmicutes,24II4@186801|Clostridia	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HKD1_k127_619907_6	1121334.KB911069_gene1530	8.431e-26	116.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia,3WJWF@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_619907_1	1476973.JMMB01000007_gene2895	7.453e-118	382.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,25QV8@186804|Peptostreptococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_619907_3	1476973.JMMB01000007_gene2896	6.718e-45	165.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,25RPN@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HKD1_k127_619907_8	1305836.AXVE01000015_gene3009	1.423e-14	75.0	COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,4HDBF@91061|Bacilli,26EVK@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD1_k127_619907_4	1408823.AXUS01000002_gene944	2.49e-44	164.0	COG2323@1|root,COG2323@2|Bacteria,1V1AI@1239|Firmicutes,24EAT@186801|Clostridia,25T6K@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HKD1_k127_6261642_0	1476973.JMMB01000007_gene2168	1.02e-87	290.0	COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae	186801|Clostridia	L	DnaB-like helicase N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
HKD1_k127_6261642_2	1476973.JMMB01000007_gene2163	2.252e-36	139.0	COG5566@1|root,COG5566@2|Bacteria,1VNYR@1239|Firmicutes,2535W@186801|Clostridia,25UDG@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_6261642_1	1476973.JMMB01000007_gene279	1.068e-78	264.0	29G4A@1|root,30321@2|Bacteria,1UD87@1239|Firmicutes,24YAX@186801|Clostridia,25TAB@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6261642_8	1345695.CLSA_c32720	0.0003445	50.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,36GDB@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
HKD1_k127_6261642_6	1476973.JMMB01000007_gene2166	4.403e-17	81.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,25JJ2@186801|Clostridia,25UAK@186804|Peptostreptococcaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_6261642_5	1301100.HG529227_gene5463	6.325e-22	96.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_6261642_4	1476973.JMMB01000007_gene2164	7.657e-24	102.0	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,25JD3@186801|Clostridia,25S08@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_6261642_3	1476973.JMMB01000001_gene3360	2.189e-28	115.0	COG2522@1|root,COG2522@2|Bacteria,1V00D@1239|Firmicutes,24H1A@186801|Clostridia,25SAX@186804|Peptostreptococcaceae	186801|Clostridia	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6261642_7	1476973.JMMB01000005_gene3461	8.715e-12	65.0	2CDN8@1|root,2ZWE6@2|Bacteria,1W569@1239|Firmicutes,24VW0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_59	1301100.HG529418_gene3051	8.036e-51	181.0	COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,24QWE@186801|Clostridia,36NS4@31979|Clostridiaceae	186801|Clostridia	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
HKD1_k127_6379909_72	1476973.JMMB01000007_gene206	1.603e-36	139.0	2FCQQ@1|root,3210P@2|Bacteria,1UEEM@1239|Firmicutes,252R2@186801|Clostridia,25RTP@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_63	1476973.JMMB01000007_gene207	1.748e-44	163.0	COG4980@1|root,COG4980@2|Bacteria,1VZGW@1239|Firmicutes,252MR@186801|Clostridia,25RWN@186804|Peptostreptococcaceae	186801|Clostridia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
HKD1_k127_6379909_1	1301100.HG529418_gene3048	0.0	1449.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HKD1_k127_6379909_3	1476973.JMMB01000007_gene209	0.0	1203.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25QWZ@186804|Peptostreptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HKD1_k127_6379909_17	1476973.JMMB01000007_gene210	6.653e-224	696.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25R56@186804|Peptostreptococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HKD1_k127_6379909_74	1476973.JMMB01000007_gene211	6.603e-31	122.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,25RV8@186804|Peptostreptococcaceae	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HKD1_k127_6379909_19	1476973.JMMB01000007_gene212	3.756e-219	682.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,25QH8@186804|Peptostreptococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HKD1_k127_6379909_10	1301100.HG529418_gene3043	8.223e-270	832.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HKD1_k127_6379909_78	1476973.JMMB01000007_gene214	6.388e-17	80.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,25RUD@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HKD1_k127_6379909_56	1476973.JMMB01000007_gene215	7.594e-57	200.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,25RS0@186804|Peptostreptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HKD1_k127_6379909_65	1151292.QEW_4342	2.8e-41	153.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,25RU5@186804|Peptostreptococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HKD1_k127_6379909_38	1476973.JMMB01000007_gene216	1.047e-123	398.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,25R1H@186804|Peptostreptococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HKD1_k127_6379909_64	1487921.DP68_12660	2.09e-44	168.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
HKD1_k127_6379909_8	1476973.JMMB01000007_gene218	3.484e-273	843.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25QGZ@186804|Peptostreptococcaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HKD1_k127_6379909_5	1476973.JMMB01000007_gene219	0.0	1172.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25QGE@186804|Peptostreptococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HKD1_k127_6379909_39	500633.CLOHIR_02113	1.822e-123	398.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,25QEA@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HKD1_k127_6379909_33	1301100.HG529418_gene3035	9.874e-138	441.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,36DCH@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD1_k127_6379909_30	1301100.HG529418_gene3034	1.474e-148	473.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,36E15@31979|Clostridiaceae	186801|Clostridia	D	sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HKD1_k127_6379909_32	1476973.JMMB01000007_gene224	1.307e-142	456.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,25RTZ@186804|Peptostreptococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HKD1_k127_6379909_27	1476973.JMMB01000007_gene225	1.108e-161	510.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25R1M@186804|Peptostreptococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_6379909_53	1476973.JMMB01000007_gene225	3.341e-61	211.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25R1M@186804|Peptostreptococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HKD1_k127_6379909_16	1476973.JMMB01000007_gene226	2.279e-225	704.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1VHJ0@1239|Firmicutes,247R0@186801|Clostridia,25QJ2@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,TPR_12,TPR_8
HKD1_k127_6379909_42	1476973.JMMB01000007_gene227	6.844e-105	342.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25RGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
HKD1_k127_6379909_66	1476973.JMMB01000007_gene228	6.253e-41	152.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,25NV6@186801|Clostridia,25RWC@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
HKD1_k127_6379909_75	1476973.JMMB01000007_gene229	1.732e-28	114.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,25RUT@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
HKD1_k127_6379909_13	1476973.JMMB01000007_gene230	1.304e-246	764.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25QEY@186804|Peptostreptococcaceae	186801|Clostridia	E	COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HKD1_k127_6379909_58	1476973.JMMB01000007_gene231	4.702e-51	181.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,25RN8@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HKD1_k127_6379909_45	1301100.HG529418_gene3025	1.549e-92	304.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,36IQ6@31979|Clostridiaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb3	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HKD1_k127_6379909_69	1301100.HG529418_gene3024	1.491e-38	144.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HKD1_k127_6379909_55	1476973.JMMB01000007_gene234	6.122e-57	199.0	2E81H@1|root,332FJ@2|Bacteria,1VEGN@1239|Firmicutes,24NHK@186801|Clostridia,25RNG@186804|Peptostreptococcaceae	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
HKD1_k127_6379909_35	1476973.JMMB01000007_gene235	5.994e-133	431.0	COG4241@1|root,COG4241@2|Bacteria,1UECP@1239|Firmicutes,25J8N@186801|Clostridia,25RGY@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
HKD1_k127_6379909_4	1476973.JMMB01000007_gene236	0.0	1178.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,25QFS@186804|Peptostreptococcaceae	186801|Clostridia	T	DHHA1 domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HKD1_k127_6379909_49	1476973.JMMB01000007_gene237	1.339e-75	255.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,25RF4@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HKD1_k127_6379909_7	1476973.JMMB01000007_gene238	5.383e-274	844.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,25QS4@186804|Peptostreptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HKD1_k127_6379909_70	1476973.JMMB01000007_gene239	5.091e-37	142.0	28RZZ@1|root,2ZEBW@2|Bacteria,1W6M4@1239|Firmicutes,252V1@186801|Clostridia,25UEI@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_9	1476973.JMMB01000007_gene240	5.28e-272	838.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25QZ5@186804|Peptostreptococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HKD1_k127_6379909_80	1408823.AXUS01000073_gene990	7.961e-13	68.0	2DR59@1|root,33A7S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_23	1476973.JMMB01000007_gene241	2.507e-184	579.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,25QKK@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA replication protein DnaC	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HKD1_k127_6379909_20	1476973.JMMB01000007_gene242	8.162e-206	642.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,25R1R@186804|Peptostreptococcaceae	186801|Clostridia	L	Replication initiation and membrane attachment	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD1_k127_6379909_6	1476973.JMMB01000007_gene243	4.982e-274	849.0	COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,24AYS@186801|Clostridia,25QI4@186804|Peptostreptococcaceae	186801|Clostridia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
HKD1_k127_6379909_26	1476973.JMMB01000007_gene244	6.076e-162	512.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,25QID@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HKD1_k127_6379909_44	1476973.JMMB01000007_gene245	3.752e-93	306.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25RPM@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HKD1_k127_6379909_52	469615.FGAG_00423	1.166e-65	233.0	COG4271@1|root,COG4271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi_C,TIR-like
HKD1_k127_6379909_60	645991.Sgly_1336	2.627e-49	180.0	2BH95@1|root,32BAK@2|Bacteria,1V6MD@1239|Firmicutes,24WC8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_71	536233.CLO_3117	1.37e-36	157.0	COG2333@1|root,COG2333@2|Bacteria,1W1B8@1239|Firmicutes,253IC@186801|Clostridia	186801|Clostridia	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_73	1408823.AXUS01000014_gene1339	1.221e-32	127.0	COG4728@1|root,COG4728@2|Bacteria,1UEXS@1239|Firmicutes,25JXA@186801|Clostridia,25TS8@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
HKD1_k127_6379909_68	546271.Selsp_2048	2.386e-39	154.0	COG0717@1|root,COG0717@2|Bacteria,1V1BE@1239|Firmicutes,4H43I@909932|Negativicutes	909932|Negativicutes	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HKD1_k127_6379909_76	1391646.AVSU01000117_gene833	7.359e-24	104.0	28PTP@1|root,335EY@2|Bacteria,1VZWA@1239|Firmicutes,24W4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_41	1476973.JMMB01000007_gene252	7.145e-118	380.0	2BMFE@1|root,32G00@2|Bacteria,1UF43@1239|Firmicutes,25K4V@186801|Clostridia,25U4X@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_47	1476973.JMMB01000007_gene253	1.835e-88	298.0	29SV9@1|root,31VZX@2|Bacteria,1V9FK@1239|Firmicutes,24MEK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_28	1211817.CCAT010000085_gene1932	7.339e-158	500.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,249W3@186801|Clostridia,36DQM@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
HKD1_k127_6379909_51	1391646.AVSU01000091_gene478	4.498e-70	238.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,25TC9@186804|Peptostreptococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
HKD1_k127_6379909_67	445973.CLOBAR_01067	6.108e-40	168.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Cadherin-like,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Laminin_G_3,SLH,fn3
HKD1_k127_6379909_46	445973.CLOBAR_00881	3.765e-91	321.0	COG0791@1|root,COG0791@2|Bacteria,1VB5V@1239|Firmicutes,24MS3@186801|Clostridia	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HKD1_k127_6379909_37	1121324.CLIT_10c03720	2.537e-131	422.0	COG2267@1|root,COG2267@2|Bacteria,1UJEV@1239|Firmicutes,24M73@186801|Clostridia	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
HKD1_k127_6379909_43	1121289.JHVL01000001_gene1924	1.547e-99	329.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,36DGI@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_6379909_29	1304284.L21TH_1675	1.323e-149	487.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DKF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_6379909_40	2325.TKV_c01910	3.51e-120	392.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,42FWZ@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
HKD1_k127_6379909_54	2325.TKV_c01900	3.106e-58	211.0	COG0348@1|root,COG0348@2|Bacteria,1V8RW@1239|Firmicutes,24JXS@186801|Clostridia,42GUZ@68295|Thermoanaerobacterales	186801|Clostridia	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6379909_61	574375.BAGA_17000	5.759e-47	174.0	COG3238@1|root,COG3238@2|Bacteria,1V7PX@1239|Firmicutes	1239|Firmicutes	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HKD1_k127_6379909_62	315730.BcerKBAB4_3163	4.05e-45	168.0	COG3238@1|root,COG3238@2|Bacteria,1V6I0@1239|Firmicutes,4IEWJ@91061|Bacilli,1ZEM5@1386|Bacillus	91061|Bacilli	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HKD1_k127_6379909_48	1211817.CCAT010000083_gene1424	3.606e-86	292.0	COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,24H46@186801|Clostridia,36IIT@31979|Clostridiaceae	186801|Clostridia	K	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_6379909_31	1391646.AVSU01000040_gene1838	8.44e-146	473.0	2CH8Y@1|root,32S5K@2|Bacteria,1VDN2@1239|Firmicutes,24EY4@186801|Clostridia,25TMP@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx1
HKD1_k127_6379909_81	1476973.JMMB01000007_gene3191	5.303e-09	58.0	COG0791@1|root,COG0791@2|Bacteria,1UXBH@1239|Firmicutes,24ZD1@186801|Clostridia,25S38@186804|Peptostreptococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HKD1_k127_6379909_50	1476973.JMMB01000007_gene321	7.506e-71	240.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,24J9K@186801|Clostridia,25TK9@186804|Peptostreptococcaceae	186801|Clostridia	P	PhnA Zinc-Ribbon	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
HKD1_k127_6379909_24	1476973.JMMB01000007_gene322	1.253e-182	574.0	COG0451@1|root,COG0451@2|Bacteria,1TSUN@1239|Firmicutes,2485S@186801|Clostridia,25S57@186804|Peptostreptococcaceae	186801|Clostridia	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
HKD1_k127_6379909_14	1476973.JMMB01000007_gene323	8.852e-234	726.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,25SJ7@186804|Peptostreptococcaceae	186801|Clostridia	H	Cys/Met metabolism PLP-dependent enzyme	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_6379909_15	1476973.JMMB01000007_gene326	1.751e-232	723.0	COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,249V9@186801|Clostridia,25SER@186804|Peptostreptococcaceae	186801|Clostridia	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
HKD1_k127_6379909_21	1391646.AVSU01000075_gene2815	3.297e-202	631.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25T26@186804|Peptostreptococcaceae	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HKD1_k127_6379909_25	1476973.JMMB01000007_gene328	1.632e-180	568.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25T67@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HKD1_k127_6379909_11	1476973.JMMB01000007_gene331	2.905e-265	822.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,25SV0@186804|Peptostreptococcaceae	186801|Clostridia	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
HKD1_k127_6379909_79	1301100.HG529415_gene2952	9.257e-17	79.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,36I3G@31979|Clostridiaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HKD1_k127_6379909_57	1128398.Curi_c25330	3.616e-51	190.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,269GX@186813|unclassified Clostridiales	186801|Clostridia	E	Vitamin B12 dependent methionine synthase, activation domain	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
HKD1_k127_6379909_2	1476973.JMMB01000007_gene337	0.0	1334.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,25QVW@186804|Peptostreptococcaceae	186801|Clostridia	E	Homocysteine S-methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
HKD1_k127_6379909_22	1476973.JMMB01000007_gene339	4.923e-192	601.0	COG0524@1|root,COG0524@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,25QR3@186804|Peptostreptococcaceae	186801|Clostridia	G	pfkB family carbohydrate kinase	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
HKD1_k127_6379909_12	1476973.JMMB01000007_gene340	4.031e-253	782.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,25QZJ@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
HKD1_k127_6379909_36	1476973.JMMB01000007_gene341	6.72e-133	428.0	COG0778@1|root,COG0778@2|Bacteria,1VCIT@1239|Firmicutes,25CKS@186801|Clostridia,25RC5@186804|Peptostreptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
HKD1_k127_6379909_34	1301100.HG529414_gene2944	5.528e-136	434.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,36M3M@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
HKD1_k127_6379909_18	1476973.JMMB01000007_gene343	3.836e-222	689.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,25QDV@186804|Peptostreptococcaceae	186801|Clostridia	F	Carbamoyl-phosphate synthetase glutamine chain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HKD1_k127_6379909_0	1476973.JMMB01000007_gene344	0.0	2047.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,25QUT@186804|Peptostreptococcaceae	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
HKD1_k127_6395499_37	1476973.JMMB01000007_gene1454	2.395e-44	164.0	COG0699@1|root,COG0699@2|Bacteria,1UEI4@1239|Firmicutes,24ZFS@186801|Clostridia,25SB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD1_k127_6395499_4	1301100.HG529343_gene2433	2.898e-235	739.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
HKD1_k127_6395499_12	1476973.JMMB01000007_gene1460	4.67e-170	539.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,25S1U@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
HKD1_k127_6395499_44	1301100.HG529343_gene2427	1.204e-06	51.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,36E6M@31979|Clostridiaceae	186801|Clostridia	P	Ferrous iron transport protein B	feoB2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HKD1_k127_6395499_17	1476973.JMMB01000007_gene1463	1.957e-142	458.0	2EYQ4@1|root,33RXK@2|Bacteria,1VSWR@1239|Firmicutes,2495K@186801|Clostridia,25RCM@186804|Peptostreptococcaceae	186801|Clostridia	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
HKD1_k127_6395499_27	1301100.HG529342_gene2458	6.524e-88	296.0	COG0584@1|root,COG0584@2|Bacteria,1V3Z1@1239|Firmicutes,24C71@186801|Clostridia,36IIP@31979|Clostridiaceae	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
HKD1_k127_6395499_5	1301100.HG529342_gene2457	5.199e-235	729.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,36DGG@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HKD1_k127_6395499_29	1476973.JMMB01000007_gene1465	4.166e-78	265.0	29UMJ@1|root,30FZ3@2|Bacteria,1UEWS@1239|Firmicutes,25JW7@186801|Clostridia,25TNC@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_35	1476973.JMMB01000007_gene1466	9.65e-45	165.0	COG3296@1|root,COG3296@2|Bacteria,1UF3R@1239|Firmicutes,251X1@186801|Clostridia,25UC8@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
HKD1_k127_6395499_14	1476973.JMMB01000007_gene1467	3.271e-155	494.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,25QYH@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_6395499_25	1391646.AVSU01000001_gene207	1.083e-107	350.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25S8X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD1_k127_6395499_34	1476973.JMMB01000007_gene1640	1.642e-55	203.0	2BA4J@1|root,323IF@2|Bacteria,1UQ1P@1239|Firmicutes,257PD@186801|Clostridia,25U4Q@186804|Peptostreptococcaceae	186801|Clostridia	-	-	cotA	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_8	1476973.JMMB01000007_gene1469	1.95e-204	640.0	COG1143@1|root,COG2006@1|root,COG1143@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,25SZJ@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
HKD1_k127_6395499_41	1347392.CCEZ01000043_gene88	3.724e-19	94.0	COG2761@1|root,COG2761@2|Bacteria,1TRSS@1239|Firmicutes,25D1S@186801|Clostridia,36U5P@31979|Clostridiaceae	186801|Clostridia	Q	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
HKD1_k127_6395499_39	1476973.JMMB01000007_gene1470	6.393e-32	126.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia,25TK2@186804|Peptostreptococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD1_k127_6395499_3	1476973.JMMB01000007_gene1471	1.045e-239	745.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,25R78@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HKD1_k127_6395499_9	1476973.JMMB01000007_gene1475	4.106e-201	632.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25SYP@186804|Peptostreptococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HKD1_k127_6395499_20	1476973.JMMB01000007_gene1476	2.936e-121	392.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,25QCU@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_6395499_13	1301100.HG529339_gene2409	1.266e-156	501.0	COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,25CIX@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_6395499_22	1476973.JMMB01000007_gene1478	4.302e-115	372.0	29UKF@1|root,30FXW@2|Bacteria,1UEUJ@1239|Firmicutes,25JU2@186801|Clostridia,25TGZ@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_10	1476973.JMMB01000007_gene1479	3.066e-194	612.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25R7Q@186804|Peptostreptococcaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HKD1_k127_6395499_19	1476973.JMMB01000007_gene1491	2.56e-125	402.0	COG1182@1|root,COG1182@2|Bacteria,1UYPQ@1239|Firmicutes,25CAR@186801|Clostridia,25SCM@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
HKD1_k127_6395499_6	1476973.JMMB01000007_gene1492	7.766e-231	720.0	COG1113@1|root,COG1113@2|Bacteria,1VTQW@1239|Firmicutes,25EF5@186801|Clostridia,25QTQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_6395499_21	1301100.HG529336_gene3402	1.702e-119	389.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,36G9H@31979|Clostridiaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HKD1_k127_6395499_26	1151292.QEW_1973	1.261e-94	320.0	COG0760@1|root,COG0760@2|Bacteria,1VS75@1239|Firmicutes,24ZMI@186801|Clostridia,25SPD@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3,SurA_N_3
HKD1_k127_6395499_46	1301100.HG529336_gene3399	4.633e-05	46.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia,36UVW@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
HKD1_k127_6395499_33	272563.CD630_15620	5.827e-61	218.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,25TKM@186804|Peptostreptococcaceae	186801|Clostridia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HKD1_k127_6395499_43	1391646.AVSU01000010_gene93	4.017e-17	85.0	29UPZ@1|root,30G1P@2|Bacteria,1UF1K@1239|Firmicutes,254XZ@186801|Clostridia,25U6J@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_15	1476973.JMMB01000007_gene1621	3.382e-148	473.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,24A46@186801|Clostridia,25SW5@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_6395499_45	1461580.CCAS010000068_gene4042	8.278e-06	48.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HA1R@91061|Bacilli	91061|Bacilli	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD1_k127_6395499_30	1476973.JMMB01000007_gene1640	8.48e-75	258.0	2BA4J@1|root,323IF@2|Bacteria,1UQ1P@1239|Firmicutes,257PD@186801|Clostridia,25U4Q@186804|Peptostreptococcaceae	186801|Clostridia	-	-	cotA	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_38	1499689.CCNN01000014_gene3260	2.162e-41	161.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,24MYD@186801|Clostridia,36IF7@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
HKD1_k127_6395499_16	1292035.H476_2517	7.42e-145	464.0	COG2006@1|root,COG2006@2|Bacteria,1TRQ9@1239|Firmicutes,248BF@186801|Clostridia,25RWD@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
HKD1_k127_6395499_40	1476973.JMMB01000007_gene1644	1.883e-24	104.0	29VJ8@1|root,30H1R@2|Bacteria,1UH0D@1239|Firmicutes,254X0@186801|Clostridia,25UD1@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6395499_7	1476973.JMMB01000007_gene1645	1.151e-212	663.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25T5E@186804|Peptostreptococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HKD1_k127_6395499_32	1301100.HG529308_gene383	2.016e-63	218.0	COG4810@1|root,COG4810@2|Bacteria,1VB54@1239|Firmicutes,24JK9@186801|Clostridia,36IQ9@31979|Clostridiaceae	186801|Clostridia	E	PFAM microcompartments protein	eutS	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
HKD1_k127_6395499_28	1476973.JMMB01000007_gene1647	1.796e-87	289.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24HGZ@186801|Clostridia,25TCD@186804|Peptostreptococcaceae	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HKD1_k127_6395499_23	1476973.JMMB01000007_gene1648	8.084e-115	372.0	COG3707@1|root,COG3707@2|Bacteria,1U6TA@1239|Firmicutes,24G9P@186801|Clostridia,25SS9@186804|Peptostreptococcaceae	186801|Clostridia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
HKD1_k127_6395499_2	1476973.JMMB01000007_gene1649	1.001e-278	860.0	COG3920@1|root,COG3920@2|Bacteria,1TRK3@1239|Firmicutes,248MJ@186801|Clostridia,25SGR@186804|Peptostreptococcaceae	186801|Clostridia	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2
HKD1_k127_6395499_1	1476973.JMMB01000007_gene1650	5.22e-287	884.0	COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,24BB7@186801|Clostridia,25SVQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Ethanolamine utilisation protein EutA	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
HKD1_k127_6395499_0	1476973.JMMB01000007_gene1651	9.33e-297	910.0	COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,248P5@186801|Clostridia,25SX9@186804|Peptostreptococcaceae	186801|Clostridia	E	Ethanolamine ammonia lyase large subunit (EutB)	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
HKD1_k127_6395499_11	1476973.JMMB01000007_gene1652	9.078e-182	569.0	COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,24A5Y@186801|Clostridia,25SID@186804|Peptostreptococcaceae	186801|Clostridia	E	Ethanolamine ammonia-lyase light chain (EutC)	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
HKD1_k127_6395499_18	1476973.JMMB01000007_gene1653	2.265e-129	414.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25SPR@186804|Peptostreptococcaceae	186801|Clostridia	E	BMC	eutL	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
HKD1_k127_6395499_31	1476973.JMMB01000007_gene1654	8.556e-71	244.0	COG4577@1|root,COG4577@2|Bacteria,1VCS9@1239|Firmicutes,24HXD@186801|Clostridia,25TIY@186804|Peptostreptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HKD1_k127_6395499_24	1476973.JMMB01000007_gene1655	2.223e-111	361.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,25S35@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
HKD1_k127_6490037_2	1151292.QEW_3461	3.533e-224	702.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HKD1_k127_6490037_1	1476973.JMMB01000007_gene1831	2.225e-232	724.0	COG0673@1|root,COG0673@2|Bacteria,1TRCC@1239|Firmicutes,248FQ@186801|Clostridia,25S5D@186804|Peptostreptococcaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_6490037_3	1292035.H476_1713	2.218e-87	295.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,25TBQ@186804|Peptostreptococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HKD1_k127_6490037_0	1476973.JMMB01000007_gene1833	3.407e-242	751.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25QJC@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HKD1_k127_6527482_7	1476973.JMMB01000007_gene528	6.84e-114	368.0	COG3172@1|root,COG3172@2|Bacteria,1UZS9@1239|Firmicutes,24A97@186801|Clostridia,25T4W@186804|Peptostreptococcaceae	186801|Clostridia	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
HKD1_k127_6527482_6	1476973.JMMB01000007_gene527	3.512e-126	407.0	COG1752@1|root,COG1752@2|Bacteria,1V1ST@1239|Firmicutes,24GJT@186801|Clostridia,25RDS@186804|Peptostreptococcaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HKD1_k127_6527482_2	1476973.JMMB01000007_gene526	2.639e-257	796.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,25QMP@186804|Peptostreptococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
HKD1_k127_6527482_0	1476973.JMMB01000007_gene525	0.0	1374.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25QN0@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HKD1_k127_6527482_4	1476973.JMMB01000007_gene524	1.079e-156	496.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25QWY@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
HKD1_k127_6527482_8	445973.CLOBAR_01386	2.796e-73	253.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,24A4J@186801|Clostridia,25RAD@186804|Peptostreptococcaceae	186801|Clostridia	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
HKD1_k127_6527482_9	635013.TherJR_1263	1.415e-29	119.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,262G2@186807|Peptococcaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
HKD1_k127_6527482_5	1301100.HG529410_gene164	9.709e-129	415.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,36EQF@31979|Clostridiaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
HKD1_k127_6527482_1	1151292.QEW_0498	1.527e-275	857.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,25QV4@186804|Peptostreptococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
HKD1_k127_6527482_3	1301100.HG529410_gene168	8.334e-165	522.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,36HIJ@31979|Clostridiaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HKD1_k127_6612921_48	318464.IO99_15985	1.504e-36	141.0	COG0680@1|root,COG0680@2|Bacteria,1VE76@1239|Firmicutes,24S2H@186801|Clostridia,36MUP@31979|Clostridiaceae	186801|Clostridia	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
HKD1_k127_6612921_20	1391647.AVSV01000029_gene2012	5.331e-178	569.0	COG0374@1|root,COG0374@2|Bacteria,1TQMW@1239|Firmicutes,248BB@186801|Clostridia,36F7N@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
HKD1_k127_6612921_34	1487921.DP68_01135	2.199e-113	372.0	COG1740@1|root,COG1740@2|Bacteria,1TZZD@1239|Firmicutes,2489B@186801|Clostridia,36EWC@31979|Clostridiaceae	186801|Clostridia	C	Hydrogenase (NiFe) small subunit HydA	hupS	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
HKD1_k127_6612921_50	332101.JIBU02000012_gene913	2.719e-28	118.0	COG4892@1|root,COG4892@2|Bacteria,1VEGK@1239|Firmicutes,24QJ4@186801|Clostridia,36MKT@31979|Clostridiaceae	186801|Clostridia	G	PFAM cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
HKD1_k127_6612921_38	1476973.JMMB01000007_gene2447	1.231e-88	293.0	COG1633@1|root,COG1633@2|Bacteria,1V860@1239|Firmicutes,24ERW@186801|Clostridia,25T8U@186804|Peptostreptococcaceae	186801|Clostridia	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HKD1_k127_6612921_47	1301100.HG529416_gene2977	1.035e-39	152.0	COG3584@1|root,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,2493P@186801|Clostridia,36FEK@31979|Clostridiaceae	186801|Clostridia	D	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D,SH3_3
HKD1_k127_6612921_10	1476973.JMMB01000007_gene2348	4.175e-271	847.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,25SD0@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
HKD1_k127_6612921_49	1476973.JMMB01000007_gene2350	1.266e-33	130.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,24QV3@186801|Clostridia,25TY2@186804|Peptostreptococcaceae	186801|Clostridia	S	Transcriptional Coactivator p15 (PC4)	-	-	-	-	-	-	-	-	-	-	-	-	PC4
HKD1_k127_6612921_39	1476973.JMMB01000007_gene2351	1.688e-87	291.0	2BE1A@1|root,327RW@2|Bacteria,1UTND@1239|Firmicutes,253NY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612921_30	1476973.JMMB01000007_gene2352	1.375e-130	424.0	COG0758@1|root,COG0758@2|Bacteria,1V4AI@1239|Firmicutes,24IFD@186801|Clostridia,25TGY@186804|Peptostreptococcaceae	186801|Clostridia	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	-	-	-	-	-	-	-	-	-	-	-	-	DNA_processg_A
HKD1_k127_6612921_32	1301100.HG529263_gene674	2.106e-123	401.0	COG0860@1|root,COG0860@2|Bacteria,1V4B9@1239|Firmicutes,24MC5@186801|Clostridia	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HKD1_k127_6612921_0	1476973.JMMB01000007_gene2353	0.0	1838.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25T6G@186804|Peptostreptococcaceae	186801|Clostridia	KL	Bacterial SNF2 helicase associated	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HKD1_k127_6612921_18	1151292.QEW_0566	2.84e-213	671.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25S6H@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HKD1_k127_6612921_15	1476973.JMMB01000007_gene2357	3.628e-239	751.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25TB0@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
HKD1_k127_6612921_31	1304284.L21TH_0535	1.295e-129	424.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,248MC@186801|Clostridia,36ESB@31979|Clostridiaceae	186801|Clostridia	E	Alanine racemase, N-terminal domain	-	-	5.1.1.12	ko:K21898	ko00472,map00472	-	R00672	RC00302	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N
HKD1_k127_6612921_8	1476973.JMMB01000007_gene2380	1.943e-273	844.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,25S50@186804|Peptostreptococcaceae	186801|Clostridia	D	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
HKD1_k127_6612921_1	1476973.JMMB01000007_gene2381	0.0	1441.0	COG5012@1|root,COG5012@2|Bacteria,1UHX7@1239|Firmicutes,25E66@186801|Clostridia,25S4Q@186804|Peptostreptococcaceae	186801|Clostridia	S	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	oraE	-	5.4.3.5	ko:K17898	ko00472,map00472	-	R02461	RC00719	ko00000,ko00001,ko01000	-	-	-	B12-binding,Lys-AminoMut_A,OAM_dimer
HKD1_k127_6612921_46	1511.CLOST_1291	2.998e-44	164.0	2DMJP@1|root,32S0N@2|Bacteria,1V766@1239|Firmicutes,24K8E@186801|Clostridia	186801|Clostridia	S	D-ornithine 4,5-aminomutase alpha-subunit	oraS	-	5.4.3.5	ko:K17899	ko00472,map00472	-	R02461	RC00719	ko00000,ko00001,ko01000	-	-	-	OAM_alpha
HKD1_k127_6612921_6	1476973.JMMB01000007_gene2383	5.723e-283	872.0	COG1171@1|root,COG1171@2|Bacteria,1UEND@1239|Firmicutes,25JMG@186801|Clostridia,25SXM@186804|Peptostreptococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.3.1.263	ko:K21400	-	-	-	-	ko00000,ko01000	-	-	-	PALP
HKD1_k127_6612921_44	1301100.HG529262_gene727	4.24e-54	191.0	2E6IF@1|root,3315M@2|Bacteria,1VAX0@1239|Firmicutes,24N55@186801|Clostridia,36KEX@31979|Clostridiaceae	186801|Clostridia	-	-	ortA	GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	2.3.1.263	ko:K21399	-	-	-	-	ko00000,ko01000	-	-	-	-
HKD1_k127_6612921_17	1476973.JMMB01000007_gene2385	6.687e-215	669.0	COG3804@1|root,COG3804@2|Bacteria,1TRNF@1239|Firmicutes,249AS@186801|Clostridia,25SYT@186804|Peptostreptococcaceae	186801|Clostridia	S	dihydrodipicolinate reductase	ord	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
HKD1_k127_6612921_11	1476973.JMMB01000007_gene2386	9.272e-266	822.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25SPA@186804|Peptostreptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_9,PrpR_N,Sigma54_activat
HKD1_k127_6612921_35	1301100.HG529275_gene1631	4.753e-102	343.0	COG0642@1|root,COG2984@1|root,COG2205@2|Bacteria,COG2984@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Reg_prop,Y_Y_Y
HKD1_k127_6612921_26	1301100.HG529262_gene723	3.352e-136	437.0	COG2357@1|root,COG2357@2|Bacteria,1V0VY@1239|Firmicutes,24A69@186801|Clostridia,36EK9@31979|Clostridiaceae	186801|Clostridia	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
HKD1_k127_6612921_12	1476973.JMMB01000007_gene2387	1.107e-258	803.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25SEF@186804|Peptostreptococcaceae	186801|Clostridia	JKL	DbpA RNA binding domain	dbpA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HKD1_k127_6612921_40	1476973.JMMB01000007_gene2388	8.636e-81	274.0	29UN7@1|root,30FZU@2|Bacteria,1UEXR@1239|Firmicutes,251TU@186801|Clostridia,25TS5@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612921_41	1476973.JMMB01000007_gene2031	3.513e-80	282.0	29UP7@1|root,30G0T@2|Bacteria,1UEZK@1239|Firmicutes,2541J@186801|Clostridia,25U12@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612921_43	1301100.HG529275_gene1603	1.393e-54	201.0	28J4E@1|root,30WZE@2|Bacteria,1U3SM@1239|Firmicutes,24VIQ@186801|Clostridia,36T69@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6612921_33	1476973.JMMB01000007_gene2033	2.179e-116	378.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,25SMQ@186804|Peptostreptococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_6612921_45	1292035.H476_0893	4.466e-49	177.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,25RWA@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HKD1_k127_6612921_28	1476973.JMMB01000007_gene2158	5.914e-135	436.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,248TA@186801|Clostridia,25SP7@186804|Peptostreptococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,Abi
HKD1_k127_6612921_29	1476973.JMMB01000007_gene2389	1.111e-133	431.0	COG1705@1|root,COG1705@2|Bacteria,1V9TN@1239|Firmicutes,25BAZ@186801|Clostridia,25T76@186804|Peptostreptococcaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
HKD1_k127_6612921_2	1476973.JMMB01000007_gene2399	0.0	1326.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,25R2Z@186804|Peptostreptococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 65 central catalytic domain protein	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
HKD1_k127_6612921_37	1476973.JMMB01000007_gene2400	4.736e-98	324.0	COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,25B0G@186801|Clostridia,25RJG@186804|Peptostreptococcaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
HKD1_k127_6612921_19	1476973.JMMB01000007_gene2401	5.627e-183	575.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,25SMX@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HKD1_k127_6612921_4	1476973.JMMB01000007_gene2402	1.9e-322	990.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,25T4K@186804|Peptostreptococcaceae	186801|Clostridia	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10,3.2.1.70	ko:K01176,ko:K01182,ko:K01215	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
HKD1_k127_6612921_24	1476973.JMMB01000007_gene2403	2.081e-146	466.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25S66@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HKD1_k127_6612921_23	1301100.HG529262_gene703	3.359e-158	503.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HKD1_k127_6612921_14	1301100.HG529262_gene702	2.957e-250	775.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,36GDC@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
HKD1_k127_6612921_25	1476973.JMMB01000007_gene2406	8.588e-142	453.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25SXX@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HKD1_k127_6612921_36	1476973.JMMB01000007_gene2407	9.531e-99	324.0	COG1309@1|root,COG1309@2|Bacteria,1VG7J@1239|Firmicutes,25B5Y@186801|Clostridia,25UKP@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_6612921_22	1391646.AVSU01000134_gene3304	1.81e-162	529.0	COG1289@1|root,COG1289@2|Bacteria,1TQSC@1239|Firmicutes,249GV@186801|Clostridia	186801|Clostridia	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HKD1_k127_6612921_21	1476973.JMMB01000007_gene2413	8.387e-166	525.0	COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,24BHY@186801|Clostridia,25R3Y@186804|Peptostreptococcaceae	186801|Clostridia	L	UV-endonuclease UvdE	uvdE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
HKD1_k127_6612921_9	1476973.JMMB01000007_gene2414	3.604e-273	847.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25R65@186804|Peptostreptococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HKD1_k127_6612921_27	1476973.JMMB01000007_gene2415	8.253e-136	437.0	COG1073@1|root,COG1073@2|Bacteria,1V2C5@1239|Firmicutes,25EB6@186801|Clostridia,25R9V@186804|Peptostreptococcaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5,Rhodanese
HKD1_k127_6612921_52	1301100.HG529415_gene2968	2.051e-27	111.0	COG1141@1|root,COG1141@2|Bacteria,1VKVT@1239|Firmicutes,24RTU@186801|Clostridia,36MZI@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	fdxA	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
HKD1_k127_6612921_3	1391646.AVSU01000160_gene187	0.0	1063.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,25QRW@186804|Peptostreptococcaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	-	-	-	-	-	-	-	-	-	-	-	-	Prismane
HKD1_k127_6612921_5	1476973.JMMB01000007_gene2473	1.353e-294	905.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,25QMQ@186804|Peptostreptococcaceae	186801|Clostridia	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HKD1_k127_6612921_51	1301100.HG529354_gene4333	1.016e-27	113.0	2CF54@1|root,3249U@2|Bacteria,1UQKU@1239|Firmicutes,24VCN@186801|Clostridia,36VF2@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3787)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3787
HKD1_k127_6612921_16	1292035.H476_1151	1.763e-225	711.0	COG1404@1|root,COG1404@2|Bacteria,1VRK5@1239|Firmicutes,249M4@186801|Clostridia,25S2A@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_6612921_7	1476973.JMMB01000007_gene2478	6.624e-278	872.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25QF5@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HKD1_k127_6612921_13	1476973.JMMB01000007_gene1714	1.512e-256	794.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,25QQT@186804|Peptostreptococcaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HKD1_k127_6622237_175	1476973.JMMB01000007_gene1862	3.369e-17	80.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25TZ4@186804|Peptostreptococcaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HKD1_k127_6622237_19	1292035.H476_1485	6.566e-270	837.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,25S6S@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid permease	yjeM	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HKD1_k127_6622237_52	1476973.JMMB01000007_gene2046	3.511e-147	471.0	COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,24BA5@186801|Clostridia,25STG@186804|Peptostreptococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
HKD1_k127_6622237_122	1476973.JMMB01000007_gene2036	4.958e-60	212.0	29VVC@1|root,30HD5@2|Bacteria,1UHGU@1239|Firmicutes,255UE@186801|Clostridia,25U4F@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_154	1476973.JMMB01000007_gene2045	4.019e-28	117.0	29UQY@1|root,30G2W@2|Bacteria,1UF3M@1239|Firmicutes,25K4E@186801|Clostridia,25UBW@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_173	1476973.JMMB01000007_gene2044	1.151e-17	83.0	29UQQ@1|root,30G2K@2|Bacteria,1UF35@1239|Firmicutes,2558Y@186801|Clostridia,25UAH@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_36	1476973.JMMB01000007_gene2035	2.682e-204	642.0	COG0477@1|root,COG2814@2|Bacteria,1TSR2@1239|Firmicutes,24803@186801|Clostridia,25SEX@186804|Peptostreptococcaceae	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HKD1_k127_6622237_21	1476973.JMMB01000007_gene1736	2.514e-269	837.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25QKI@186804|Peptostreptococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HKD1_k127_6622237_143	1391646.AVSU01000104_gene2229	3.372e-39	148.0	COG0662@1|root,COG0662@2|Bacteria,1UI0P@1239|Firmicutes,24SCP@186801|Clostridia,25U4K@186804|Peptostreptococcaceae	186801|Clostridia	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HKD1_k127_6622237_72	536233.CLO_3100	6.934e-120	389.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,36DRQ@31979|Clostridiaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
HKD1_k127_6622237_94	1292035.H476_2513	2.856e-90	302.0	COG1284@1|root,COG1284@2|Bacteria,1V2BR@1239|Firmicutes,247P9@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HKD1_k127_6622237_17	1476973.JMMB01000007_gene2010	5.184e-301	930.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25RR9@186804|Peptostreptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HKD1_k127_6622237_65	1476973.JMMB01000007_gene2009	7.259e-126	406.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,25RVX@186804|Peptostreptococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
HKD1_k127_6622237_47	1476973.JMMB01000007_gene2008	2.569e-159	509.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,25T5T@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HKD1_k127_6622237_26	1476973.JMMB01000007_gene2007	1.609e-242	753.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,25QDP@186804|Peptostreptococcaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
HKD1_k127_6622237_66	1476973.JMMB01000007_gene2006	1.698e-124	400.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,25SM2@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HKD1_k127_6622237_30	1476973.JMMB01000007_gene2005	2.489e-227	707.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,25R19@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
HKD1_k127_6622237_49	1301100.HG529268_gene607	1.294e-155	493.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,36E47@31979|Clostridiaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HKD1_k127_6622237_34	1301100.HG529268_gene608	1.695e-208	655.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
HKD1_k127_6622237_69	1476973.JMMB01000007_gene1999	1.54e-122	394.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25SWG@186804|Peptostreptococcaceae	186801|Clostridia	G	Transaldolase/Fructose-6-phosphate aldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HKD1_k127_6622237_44	1476973.JMMB01000007_gene1997	5.127e-167	528.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25QVR@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,DUF2156
HKD1_k127_6622237_112	536232.CLM_0771	2.131e-68	239.0	COG0664@1|root,COG0664@2|Bacteria,1V5MZ@1239|Firmicutes,24AQS@186801|Clostridia,36G37@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, Crp Fnr family(	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HKD1_k127_6622237_29	1476973.JMMB01000007_gene1995	1.943e-228	711.0	COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,24YMC@186801|Clostridia,25UKC@186804|Peptostreptococcaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HKD1_k127_6622237_55	1476973.JMMB01000007_gene1982	1.202e-139	452.0	COG1664@1|root,COG1664@2|Bacteria,1V1NS@1239|Firmicutes,24TEV@186801|Clostridia,25U0C@186804|Peptostreptococcaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_70	1476973.JMMB01000007_gene1981	4.093e-122	397.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HKD1_k127_6622237_32	1128398.Curi_c28040	3.065e-223	697.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,26826@186813|unclassified Clostridiales	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
HKD1_k127_6622237_133	1195236.CTER_1143	4.505e-50	180.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,24QSV@186801|Clostridia,3WKIG@541000|Ruminococcaceae	186801|Clostridia	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HKD1_k127_6622237_152	1391646.AVSU01000067_gene723	1.132e-29	120.0	COG0640@1|root,COG0640@2|Bacteria,1VGR2@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD1_k127_6622237_50	720554.Clocl_0229	1.5e-153	490.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,3WHHN@541000|Ruminococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
HKD1_k127_6622237_168	431943.CKL_1713	3.644e-23	100.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,36MSQ@31979|Clostridiaceae	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
HKD1_k127_6622237_131	1292035.H476_2721	1.117e-51	185.0	COG0640@1|root,COG0640@2|Bacteria,1V9KK@1239|Firmicutes,24NXW@186801|Clostridia,25TUG@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HKD1_k127_6622237_62	1476973.JMMB01000007_gene1988	1.213e-129	417.0	COG0639@1|root,COG0639@2|Bacteria,1UYXB@1239|Firmicutes,24D3D@186801|Clostridia,25RX0@186804|Peptostreptococcaceae	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
HKD1_k127_6622237_35	1476973.JMMB01000007_gene1987	3.998e-205	641.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia,25S5C@186804|Peptostreptococcaceae	186801|Clostridia	P	SBF-like CPA transporter family (DUF4137)	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HKD1_k127_6622237_125	1476973.JMMB01000007_gene1986	1.103e-55	196.0	2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,25N6G@186801|Clostridia,25U9Z@186804|Peptostreptococcaceae	186801|Clostridia	S	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
HKD1_k127_6622237_10	1476973.JMMB01000007_gene1985	0.0	1113.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,25T55@186804|Peptostreptococcaceae	186801|Clostridia	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
HKD1_k127_6622237_135	1304875.JAFZ01000001_gene1944	1.864e-46	172.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA_2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HKD1_k127_6622237_104	509191.AEDB02000104_gene3831	3.436e-79	270.0	COG4232@1|root,COG4232@2|Bacteria,1V9UQ@1239|Firmicutes,24DK4@186801|Clostridia,3WJGE@541000|Ruminococcaceae	186801|Clostridia	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
HKD1_k127_6622237_113	1301100.HG529303_gene3112	3.148e-68	236.0	COG4871@1|root,COG4871@2|Bacteria,1V7YF@1239|Firmicutes,24KYS@186801|Clostridia,36RWM@31979|Clostridiaceae	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
HKD1_k127_6622237_190	646529.Desaci_1612	0.0001461	47.0	2EUKE@1|root,33N2B@2|Bacteria,1VMTK@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_80	536233.CLO_2014	1.665e-103	341.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_6622237_12	1476973.JMMB01000007_gene2367	0.0	1022.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,25QRV@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_6622237_93	1301100.HG529262_gene733	1.938e-90	311.0	2EIND@1|root,33CDR@2|Bacteria,1VKQB@1239|Firmicutes,24V5F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_59	1476973.JMMB01000007_gene2361	4.719e-133	426.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,25RHD@186804|Peptostreptococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_6622237_43	1476973.JMMB01000007_gene2360	1.932e-172	546.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25S1V@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_6622237_58	1476973.JMMB01000007_gene2359	8.781e-134	427.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25R9H@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_6622237_2	1476973.JMMB01000007_gene2358	0.0	1345.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,25QR0@186804|Peptostreptococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HKD1_k127_6622237_147	1391646.AVSU01000015_gene3043	6.014e-35	140.0	COG4512@1|root,COG4512@2|Bacteria,1VKH5@1239|Firmicutes,24QIQ@186801|Clostridia,25TSW@186804|Peptostreptococcaceae	186801|Clostridia	KOT	Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
HKD1_k127_6622237_90	1476973.JMMB01000007_gene1978	1.543e-93	312.0	COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,24AXT@186801|Clostridia,25SZ5@186804|Peptostreptococcaceae	186801|Clostridia	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_6622237_38	545243.BAEV01000010_gene1067	4.697e-196	616.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,36DKD@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HKD1_k127_6622237_39	1391646.AVSU01000026_gene2342	6.281e-189	599.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25SUZ@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_6622237_134	572544.Ilyop_0649	7.029e-50	179.0	COG1733@1|root,COG1733@2|Bacteria,37A9P@32066|Fusobacteria	32066|Fusobacteria	K	Transcriptional regulator, HxlR family	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
HKD1_k127_6622237_159	572479.Hprae_2046	7.32e-26	114.0	COG1309@1|root,COG1309@2|Bacteria,1VG3M@1239|Firmicutes,25BA9@186801|Clostridia	186801|Clostridia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
HKD1_k127_6622237_91	1476973.JMMB01000007_gene1978	3.164e-93	311.0	COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,24AXT@186801|Clostridia,25SZ5@186804|Peptostreptococcaceae	186801|Clostridia	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
HKD1_k127_6622237_28	1476973.JMMB01000007_gene1480	1.799e-229	718.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25S18@186804|Peptostreptococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_6622237_75	1117379.BABA_00290	8.65e-113	371.0	COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	isp	-	-	ko:K13275	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
HKD1_k127_6622237_1	1211817.CCAT010000040_gene208	0.0	1602.0	COG0464@1|root,COG0542@1|root,COG0464@2|Bacteria,COG0542@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,36FJP@31979|Clostridiaceae	186801|Clostridia	O	stage V sporulation protein K	spoVK	-	-	ko:K06413	-	-	-	-	ko00000	-	-	-	AAA
HKD1_k127_6622237_123	1301100.HG529285_gene7053	1.394e-58	206.0	2CFUA@1|root,32S2G@2|Bacteria,1V63K@1239|Firmicutes,24N34@186801|Clostridia,36K8A@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_45	1391646.AVSU01000132_gene2691	2.181e-166	527.0	2EINS@1|root,33CE6@2|Bacteria,1VMP8@1239|Firmicutes,247KI@186801|Clostridia,25S8W@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_63	272563.CD630_16140	4.083e-127	410.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia,25QSE@186804|Peptostreptococcaceae	186801|Clostridia	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
HKD1_k127_6622237_16	1476973.JMMB01000007_gene2022	7.877e-308	955.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,25R83@186804|Peptostreptococcaceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
HKD1_k127_6622237_115	246194.CHY_1724	4.375e-66	232.0	COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,24GV4@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HKD1_k127_6622237_74	1476973.JMMB01000007_gene2234	9.509e-115	376.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,25RSP@186804|Peptostreptococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	DUF1294,Metallophos
HKD1_k127_6622237_130	748727.CLJU_c16190	2.034e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia,36KKI@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HKD1_k127_6622237_97	1499683.CCFF01000016_gene1111	1.303e-86	304.0	29UDT@1|root,30FQG@2|Bacteria,1UEF2@1239|Firmicutes,24AEN@186801|Clostridia,36GJ5@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HKD1_k127_6622237_54	536233.CLO_3110	1.907e-140	452.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,36VGH@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HKD1_k127_6622237_71	445973.CLOBAR_02171	1.812e-121	393.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,25QDN@186804|Peptostreptococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HKD1_k127_6622237_111	1230342.CTM_22253	9.471e-69	246.0	28KIX@1|root,2ZA44@2|Bacteria,1UYPD@1239|Firmicutes,24ATH@186801|Clostridia,36RDE@31979|Clostridiaceae	186801|Clostridia	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	phaE	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
HKD1_k127_6622237_48	1410653.JHVC01000008_gene3146	5.289e-159	507.0	COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,24D2G@186801|Clostridia,36RAI@31979|Clostridiaceae	186801|Clostridia	I	PHB de-polymerase C-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
HKD1_k127_6622237_114	293826.Amet_3092	1.455e-67	231.0	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,24NB6@186801|Clostridia,36M8N@31979|Clostridiaceae	186801|Clostridia	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
HKD1_k127_6622237_6	1476973.JMMB01000007_gene2349	0.0	1213.0	COG2247@1|root,COG4193@1|root,COG2247@2|Bacteria,COG4193@2|Bacteria,1UT0U@1239|Firmicutes,248R8@186801|Clostridia,25SK3@186804|Peptostreptococcaceae	186801|Clostridia	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,CW_binding_2,ChW,Glucosaminidase,SLH
HKD1_k127_6622237_18	1476973.JMMB01000007_gene2348	2.147e-270	844.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,25SD0@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
HKD1_k127_6622237_20	1301100.HG529388_gene4963	1.05e-269	833.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,248WJ@186801|Clostridia,36FWX@31979|Clostridiaceae	186801|Clostridia	G	transporter	glpT	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
HKD1_k127_6622237_14	1499689.CCNN01000009_gene2821	1.914e-314	969.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,36DDA@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HKD1_k127_6622237_132	1476973.JMMB01000007_gene2466	1.586e-51	184.0	COG1695@1|root,COG1695@2|Bacteria,1VANP@1239|Firmicutes,25CVD@186801|Clostridia,25U8F@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HKD1_k127_6622237_121	1476973.JMMB01000007_gene2465	3.875e-60	214.0	2DM3T@1|root,31M6T@2|Bacteria,1V83C@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
HKD1_k127_6622237_186	696281.Desru_0404	4.773e-05	53.0	2DRUA@1|root,33D3J@2|Bacteria,1VK9N@1239|Firmicutes,24VV3@186801|Clostridia,266HJ@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_177	641107.CDLVIII_2962	1.637e-16	82.0	2AEWB@1|root,314TZ@2|Bacteria,1UU7Q@1239|Firmicutes,255T8@186801|Clostridia,36TQM@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_41	572544.Ilyop_1577	1.938e-175	563.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,378BR@32066|Fusobacteria	32066|Fusobacteria	C	FMN_bind	-	-	1.3.5.4,1.3.99.33	ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
HKD1_k127_6622237_151	572544.Ilyop_1577	1.669e-30	122.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,378BR@32066|Fusobacteria	32066|Fusobacteria	C	FMN_bind	-	-	1.3.5.4,1.3.99.33	ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
HKD1_k127_6622237_64	1476973.JMMB01000004_gene3423	3.514e-126	405.0	COG0778@1|root,COG0778@2|Bacteria,1V4UA@1239|Firmicutes,24EVR@186801|Clostridia	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
HKD1_k127_6622237_102	1476973.JMMB01000004_gene3424	3.251e-82	274.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,25TBT@186804|Peptostreptococcaceae	186801|Clostridia	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HKD1_k127_6622237_40	675817.VDA_001983	3.167e-177	561.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria,1XSK1@135623|Vibrionales	135623|Vibrionales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HKD1_k127_6622237_83	1476973.JMMB01000007_gene2290	2.111e-100	328.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25RMW@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD1_k127_6622237_171	545243.BAEV01000053_gene3734	2.502e-19	88.0	2EMWK@1|root,33FIW@2|Bacteria,1VMS3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_108	1476973.JMMB01000004_gene3414	7.906e-72	244.0	COG0454@1|root,COG0454@2|Bacteria,1VD9I@1239|Firmicutes,24HQI@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HKD1_k127_6622237_89	1476973.JMMB01000007_gene2320	2.078e-94	311.0	COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,24JHB@186801|Clostridia,25TDR@186804|Peptostreptococcaceae	186801|Clostridia	F	adenylate kinase (ATP-AMP transphosphorylase) K00939	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
HKD1_k127_6622237_56	999411.HMPREF1092_03065	2.989e-136	441.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471,Gram_pos_anchor
HKD1_k127_6622237_117	350688.Clos_2357	1.864e-62	218.0	2B64E@1|root,31Z19@2|Bacteria,1V8YT@1239|Firmicutes	1239|Firmicutes	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
HKD1_k127_6622237_106	1476973.JMMB01000007_gene2294	3.198e-78	274.0	2C3WT@1|root,34126@2|Bacteria,1VY31@1239|Firmicutes,251W0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_164	1476973.JMMB01000007_gene748	4.742e-25	106.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_6622237_174	1476973.JMMB01000007_gene747	1.235e-17	82.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,25JJ2@186801|Clostridia,25UAK@186804|Peptostreptococcaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_6622237_118	1487921.DP68_17185	8.086e-62	215.0	COG1846@1|root,COG1846@2|Bacteria,1VAE6@1239|Firmicutes,24INW@186801|Clostridia,36ISM@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_6622237_92	1415775.U729_2205	1.679e-92	309.0	COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,24AXT@186801|Clostridia,36IJ3@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
HKD1_k127_6622237_67	1347392.CCEZ01000019_gene1052	1.96e-124	407.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,36E6Q@31979|Clostridiaceae	186801|Clostridia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HKD1_k127_6622237_79	1487921.DP68_06620	1.006e-103	340.0	COG0796@1|root,COG0796@2|Bacteria,1V7T2@1239|Firmicutes,24C1Z@186801|Clostridia,36FR3@31979|Clostridiaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
HKD1_k127_6622237_155	1301100.HG529321_gene6077	5.539e-28	114.0	2EDTM@1|root,337NX@2|Bacteria,1VJSV@1239|Firmicutes,24ST1@186801|Clostridia,36MIR@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
HKD1_k127_6622237_116	500633.CLOHIR_00113	1.02e-62	218.0	COG3677@1|root,COG3677@2|Bacteria,1UYY4@1239|Firmicutes,248FF@186801|Clostridia,25S2T@186804|Peptostreptococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1,Zn_Tnp_IS1595
HKD1_k127_6622237_109	1301100.HG529321_gene6097	1.565e-71	250.0	2BDHD@1|root,3276J@2|Bacteria,1UT2H@1239|Firmicutes,250ZB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_136	1487921.DP68_10600	2.613e-45	168.0	COG2834@1|root,COG2834@2|Bacteria,1UB6P@1239|Firmicutes,24DTV@186801|Clostridia,36M27@31979|Clostridiaceae	186801|Clostridia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	MucB_RseB
HKD1_k127_6622237_25	1476973.JMMB01000007_gene3183	5.985e-257	801.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,25T4G@186804|Peptostreptococcaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HKD1_k127_6622237_163	931276.Cspa_c23140	4.693e-25	107.0	2BE9N@1|root,3280N@2|Bacteria,1UTXX@1239|Firmicutes,254TF@186801|Clostridia,36TSS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_142	642492.Clole_2873	3.342e-41	159.0	2F6TI@1|root,33Z9P@2|Bacteria,1VXJG@1239|Firmicutes,24P16@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_86	1499689.CCNN01000007_gene2004	6.176e-97	318.0	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,24G7Y@186801|Clostridia,36IEA@31979|Clostridiaceae	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
HKD1_k127_6622237_170	1301100.HG529329_gene4472	1.281e-19	89.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,24UDD@186801|Clostridia,36N2M@31979|Clostridiaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_6622237_178	1476973.JMMB01000007_gene1873	2.671e-16	78.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JCT@186801|Clostridia,25RZF@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_6622237_161	1476973.JMMB01000007_gene2228	2.017e-25	107.0	2E9KQ@1|root,333TF@2|Bacteria,1VHNG@1239|Firmicutes,255B9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_148	1301100.HG529327_gene4550	4.363e-33	128.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,36MK0@31979|Clostridiaceae	186801|Clostridia	K	PFAM Helix-turn-helix	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD1_k127_6622237_138	1476973.JMMB01000007_gene2230	1.911e-44	165.0	2D97U@1|root,32TST@2|Bacteria,1VDB1@1239|Firmicutes,251E4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_46	536227.CcarbDRAFT_3707	1.12e-161	511.0	COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia,36F4I@31979|Clostridiaceae	186801|Clostridia	I	Alpha beta hydrolase	-	-	1.11.1.10,3.1.1.24	ko:K00433,ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
HKD1_k127_6622237_5	1391646.AVSU01000056_gene1283	0.0	1227.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R2X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HKD1_k127_6622237_76	1292035.H476_0434	7.501e-112	366.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25QR5@186804|Peptostreptococcaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD1_k127_6622237_100	1262449.CP6013_1064	9.701e-85	284.0	COG0406@1|root,COG0406@2|Bacteria,1V3PT@1239|Firmicutes,24GK2@186801|Clostridia,36DVF@31979|Clostridiaceae	186801|Clostridia	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HKD1_k127_6622237_31	1476973.JMMB01000007_gene2027	2.731e-225	704.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,25S34@186804|Peptostreptococcaceae	186801|Clostridia	E	Branched-chain amino acid transport protein	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
HKD1_k127_6622237_160	1476973.JMMB01000007_gene2290	1.542e-25	107.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25RMW@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD1_k127_6622237_139	1292035.H476_1504	3.19e-44	162.0	2C3GY@1|root,332NU@2|Bacteria,1UPV8@1239|Firmicutes,24QHE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_184	1220589.CD32_02200	1.612e-06	50.0	2BUKN@1|root,32PX6@2|Bacteria,1U26F@1239|Firmicutes,4HVHK@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
HKD1_k127_6622237_157	1301100.HG529354_gene4338	1.803e-27	115.0	29UDK@1|root,3404Y@2|Bacteria,1VXKV@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_85	1476973.JMMB01000007_gene2290	4.506e-98	321.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25RMW@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HKD1_k127_6622237_110	1301100.HG529407_gene261	1.23e-69	240.0	2CJV9@1|root,33YF3@2|Bacteria,1VWF6@1239|Firmicutes,24KPA@186801|Clostridia,36JN7@31979|Clostridiaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
HKD1_k127_6622237_158	1301100.HG529326_gene4546	2.716e-27	113.0	2BID2@1|root,32CJ6@2|Bacteria,1UURG@1239|Firmicutes,257K4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_179	410358.Mlab_1710	1.305e-12	70.0	COG1309@1|root,arCOG02647@2157|Archaea,2XZYJ@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HKD1_k127_6622237_172	1301100.HG529329_gene4472	3.322e-19	87.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,24UDD@186801|Clostridia,36N2M@31979|Clostridiaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_6622237_185	1476973.JMMB01000007_gene1873	8.39e-06	48.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JCT@186801|Clostridia,25RZF@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_6622237_167	1301100.HG529318_gene6162	5.982e-24	102.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,24VPD@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD1_k127_6622237_99	1301100.HG529318_gene6160	2.286e-85	285.0	28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,36EHP@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2815
HKD1_k127_6622237_15	1301100.HG529318_gene6159	8.559e-312	964.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
HKD1_k127_6622237_3	1301100.HG529318_gene6158	0.0	1290.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,36EHX@31979|Clostridiaceae	186801|Clostridia	S	virulence-associated E family protein	-	-	-	-	-	-	-	-	-	-	-	-	VirE
HKD1_k127_6622237_146	1301100.HG529318_gene6157	1.366e-35	136.0	COG5566@1|root,COG5566@2|Bacteria,1VMQH@1239|Firmicutes,24V82@186801|Clostridia,36PPK@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_6622237_127	632245.CLP_2091	3.574e-55	214.0	2EI13@1|root,33BSK@2|Bacteria,1VKHD@1239|Firmicutes,24UJW@186801|Clostridia,36PDE@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_181	2325.TKV_c14560	1.328e-11	65.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	mrr	GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
HKD1_k127_6622237_96	642492.Clole_0257	5.375e-87	295.0	COG1715@1|root,COG1715@2|Bacteria,1V1TA@1239|Firmicutes,24ARK@186801|Clostridia	186801|Clostridia	L	restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
HKD1_k127_6622237_191	411154.GFO_0863	0.0002971	53.0	2FD2H@1|root,3454Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_166	1504981.KO116_0199	1.12e-24	115.0	28MN3@1|root,2ZAXQ@2|Bacteria,1R4C0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_84	698769.JFBD01000004_gene2813	4.236e-100	361.0	COG0846@1|root,COG0846@2|Bacteria,1UE4Y@1239|Firmicutes,4HRCE@91061|Bacilli	91061|Bacilli	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
HKD1_k127_6622237_7	1408422.JHYF01000003_gene668	0.0	1168.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,36GFE@31979|Clostridiaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
HKD1_k127_6622237_9	500633.CLOHIR_01918	0.0	1132.0	COG0457@1|root,COG1061@1|root,COG0457@2|Bacteria,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	HNH,Helicase_C,ResIII
HKD1_k127_6622237_60	1476973.JMMB01000007_gene2418	1.947e-132	425.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,25TE1@186804|Peptostreptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
HKD1_k127_6622237_68	1089553.Tph_c12100	2.262e-124	407.0	COG1397@1|root,COG1397@2|Bacteria,1V1PC@1239|Firmicutes,25C9W@186801|Clostridia,42J4H@68295|Thermoanaerobacterales	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HKD1_k127_6622237_187	1031288.AXAA01000010_gene470	6.735e-05	46.0	COG1061@1|root,COG1112@1|root,COG2852@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,36GFE@31979|Clostridiaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
HKD1_k127_6622237_137	1536770.R50345_10265	1.342e-44	168.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,4HJDB@91061|Bacilli,26X3K@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HKD1_k127_6622237_103	445973.CLOBAR_01046	5.362e-81	287.0	COG4194@1|root,COG4194@2|Bacteria,1V35C@1239|Firmicutes,25NIX@186801|Clostridia,25UCY@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
HKD1_k127_6622237_107	1301100.HG529388_gene4969	1.244e-73	249.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,36HZY@31979|Clostridiaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HKD1_k127_6622237_98	1476973.JMMB01000007_gene1376	5.581e-86	286.0	COG2852@1|root,COG2852@2|Bacteria,1UJ0H@1239|Firmicutes,25ET6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
HKD1_k127_6622237_126	1111728.ATYS01000054_gene3625	1.72e-55	204.0	COG0789@1|root,COG1917@1|root,COG0789@2|Bacteria,COG1917@2|Bacteria,1RCRW@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31,MerR_1
HKD1_k127_6622237_42	1385511.N783_19025	4.223e-174	555.0	COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,2Y9JR@289201|Pontibacillus	91061|Bacilli	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
HKD1_k127_6622237_61	1288.SXYLSMQ121_0479	1.193e-131	433.0	COG0531@1|root,COG0531@2|Bacteria,1V0MG@1239|Firmicutes,4HDX4@91061|Bacilli,4GYU0@90964|Staphylococcaceae	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
HKD1_k127_6622237_88	610130.Closa_3876	1.127e-95	332.0	COG2199@1|root,COG2199@2|Bacteria,1VTBQ@1239|Firmicutes,25EKJ@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4,dCache_1
HKD1_k127_6622237_4	1391646.AVSU01000037_gene2066	0.0	1288.0	COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,24DM7@186801|Clostridia,25SW4@186804|Peptostreptococcaceae	186801|Clostridia	P	Peroxidase	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
HKD1_k127_6622237_153	1195236.CTER_5033	1.825e-28	120.0	COG2832@1|root,COG2832@2|Bacteria,1V6I1@1239|Firmicutes,24U8T@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
HKD1_k127_6622237_77	1292035.H476_1387	1.96e-107	353.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25TQ6@186804|Peptostreptococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2,SH3_3,SPOR
HKD1_k127_6622237_13	1476973.JMMB01000007_gene1370	0.0	1013.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SVV@186804|Peptostreptococcaceae	186801|Clostridia	T	Cache 3/Cache 2 fusion domain	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,PAS_9,dCache_1
HKD1_k127_6622237_144	1476973.JMMB01000007_gene1370	4.203e-39	146.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SVV@186804|Peptostreptococcaceae	186801|Clostridia	T	Cache 3/Cache 2 fusion domain	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,PAS_9,dCache_1
HKD1_k127_6622237_124	445973.CLOBAR_00977	7.373e-57	213.0	COG2508@1|root,COG2508@2|Bacteria,1V4GV@1239|Firmicutes,24HFE@186801|Clostridia,25TWV@186804|Peptostreptococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HKD1_k127_6622237_87	1121874.KB892379_gene186	7.339e-97	326.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes	1239|Firmicutes	E	orniTHIne cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
HKD1_k127_6622237_53	391038.Bphy_4257	2.265e-141	458.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2W362@28216|Betaproteobacteria,1JZMY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
HKD1_k127_6622237_119	1511.CLOST_2545	2.653e-61	222.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,25QYH@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HKD1_k127_6622237_73	1345695.CLSA_c32040	2.222e-118	382.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,36FNS@31979|Clostridiaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
HKD1_k127_6622237_120	1487921.DP68_03370	1.88e-60	211.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,36JSB@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
HKD1_k127_6622237_129	1487921.DP68_03375	5.375e-54	191.0	2EA9N@1|root,334E2@2|Bacteria,1VEP2@1239|Firmicutes,25DWA@186801|Clostridia,36UFI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_150	1487921.DP68_03380	9.296e-31	123.0	2DTC7@1|root,33JNH@2|Bacteria,1VP8W@1239|Firmicutes,24UW3@186801|Clostridia,36P8R@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6622237_145	1487921.DP68_12850	1.482e-37	147.0	COG0778@1|root,COG0778@2|Bacteria,1V1BQ@1239|Firmicutes,25B0F@186801|Clostridia,36W7G@31979|Clostridiaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HKD1_k127_6622237_128	1301100.HG529388_gene4988	3.005e-54	220.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,36G1J@31979|Clostridiaceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
HKD1_k127_6622237_0	1301100.HG529388_gene4989	0.0	2195.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,36G1J@31979|Clostridiaceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
HKD1_k127_6622237_105	411490.ANACAC_00413	1.546e-78	267.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,24G44@186801|Clostridia	186801|Clostridia	C	rubredoxin	hrb	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
HKD1_k127_6622237_57	1391646.AVSU01000010_gene80	6.443e-135	438.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HKD1_k127_6622237_82	1391646.AVSU01000010_gene79	3.371e-101	334.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HKD1_k127_6622237_24	1391646.AVSU01000060_gene1097	5.671e-258	805.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,25SIQ@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
HKD1_k127_6622237_140	1476973.JMMB01000007_gene2469	2.051e-43	159.0	COG0607@1|root,COG0607@2|Bacteria,1UF0H@1239|Firmicutes,25K0S@186801|Clostridia,25U3S@186804|Peptostreptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_6622237_78	1301100.HG529410_gene154	1.076e-105	347.0	COG2717@1|root,COG2717@2|Bacteria,1VJAA@1239|Firmicutes,24FK6@186801|Clostridia,36GGZ@31979|Clostridiaceae	186801|Clostridia	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
HKD1_k127_6622237_51	1487921.DP68_01705	3.209e-153	490.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,36FFZ@31979|Clostridiaceae	186801|Clostridia	C	iron-sulfur cluster-binding protein	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16,HEAT_2
HKD1_k127_6622237_95	1340434.AXVA01000017_gene4205	2.331e-87	297.0	COG0583@1|root,COG0583@2|Bacteria,1UPRX@1239|Firmicutes,4IQQC@91061|Bacilli	91061|Bacilli	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_6622237_11	1476973.JMMB01000007_gene1372	0.0	1077.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25T38@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter transmembrane region	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_6622237_8	1476973.JMMB01000007_gene1373	0.0	1141.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25SA3@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HKD1_k127_6622237_22	1301100.HG529388_gene4961	3.034e-266	824.0	COG2234@1|root,COG2234@2|Bacteria,1V13T@1239|Firmicutes,24A8F@186801|Clostridia,36F8W@31979|Clostridiaceae	186801|Clostridia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HKD1_k127_6622237_149	1033737.CAEV01000092_gene1907	1.423e-32	131.0	COG1714@1|root,COG1714@2|Bacteria,1VIRT@1239|Firmicutes,24TSH@186801|Clostridia,36N4N@31979|Clostridiaceae	186801|Clostridia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
HKD1_k127_6622237_23	332101.JIBU02000072_gene3970	7.202e-261	820.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,36USB@31979|Clostridiaceae	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9
HKD1_k127_6622237_33	272563.CD630_28340	1.118e-221	692.0	COG0112@1|root,COG0112@2|Bacteria,1UZQE@1239|Firmicutes,248T0@186801|Clostridia,25UIG@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA1	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HKD1_k127_6622237_101	1476973.JMMB01000007_gene1241	7.011e-84	281.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V88H@1239|Firmicutes,24E8N@186801|Clostridia,25S60@186804|Peptostreptococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
HKD1_k127_6622237_81	445335.CBN_0344	2.271e-101	332.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,36E9V@31979|Clostridiaceae	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HKD1_k127_6622237_27	445335.CBN_0343	2.891e-236	736.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,36DYC@31979|Clostridiaceae	186801|Clostridia	F	permease	pbuX	-	-	ko:K03458,ko:K16345	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.4.2	-	-	Xan_ur_permease
HKD1_k127_6622237_37	1408422.JHYF01000013_gene569	1.654e-196	629.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,248HG@186801|Clostridia,36E1D@31979|Clostridiaceae	186801|Clostridia	M	CotH protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
HKD1_k127_6949018_18	1476973.JMMB01000007_gene1908	2.859e-130	418.0	COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,25SJF@186804|Peptostreptococcaceae	186801|Clostridia	C	alcohol dehydrogenase	kdd	-	1.4.1.11	ko:K18012	ko00310,map00310	-	R03349	RC00888	ko00000,ko00001,ko01000	-	-	-	ADH_zinc_N
HKD1_k127_6949018_13	1476973.JMMB01000007_gene1911	1.006e-157	499.0	COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,25SXV@186804|Peptostreptococcaceae	186801|Clostridia	S	beta-keto acid cleavage enzyme	kce	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
HKD1_k127_6949018_24	1301100.HG529329_gene4458	5.795e-69	235.0	COG1607@1|root,COG1607@2|Bacteria,1V3ZQ@1239|Firmicutes,24HF8@186801|Clostridia,36IT9@31979|Clostridiaceae	186801|Clostridia	I	Thioesterase superfamily	kal	-	4.3.1.14	ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT
HKD1_k127_6949018_9	1476973.JMMB01000007_gene1913	5.433e-179	563.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25QZ1@186804|Peptostreptococcaceae	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
HKD1_k127_6949018_14	1476973.JMMB01000007_gene1914	6.579e-151	479.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25SKK@186804|Peptostreptococcaceae	186801|Clostridia	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HKD1_k127_6949018_4	1476973.JMMB01000007_gene1915	5.682e-226	702.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25SIT@186804|Peptostreptococcaceae	186801|Clostridia	I	Acyl-CoA dehydrogenase, C-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HKD1_k127_6949018_16	1476973.JMMB01000007_gene1916	3.84e-148	472.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,25QJP@186804|Peptostreptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HKD1_k127_6949018_15	1476973.JMMB01000007_gene1917	2.758e-149	474.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25R3Z@186804|Peptostreptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HKD1_k127_6949018_8	1476973.JMMB01000007_gene1918	1.216e-193	607.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,25QJD@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HKD1_k127_6949018_28	931276.Cspa_c37680	9.73e-19	98.0	COG1251@1|root,COG1251@2|Bacteria,1V7TQ@1239|Firmicutes,24IH0@186801|Clostridia,36J81@31979|Clostridiaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
HKD1_k127_6949018_27	999411.HMPREF1092_03122	3.068e-32	138.0	COG1251@1|root,COG1251@2|Bacteria,1V7TQ@1239|Firmicutes,24IH0@186801|Clostridia,36J81@31979|Clostridiaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
HKD1_k127_6949018_29	1347368.HG964407_gene6860	1.501e-09	65.0	2DPFK@1|root,331V7@2|Bacteria,1VIAA@1239|Firmicutes,4IBS7@91061|Bacilli,1ZKSF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6949018_6	1476973.JMMB01000007_gene1919	1.339e-210	657.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,25CCC@186801|Clostridia,25UMA@186804|Peptostreptococcaceae	186801|Clostridia	E	Metallopeptidase family M24	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HKD1_k127_6949018_7	1476973.JMMB01000007_gene1920	2.946e-208	649.0	COG1600@1|root,COG1600@2|Bacteria,1V0B5@1239|Firmicutes,24FDD@186801|Clostridia,25R6X@186804|Peptostreptococcaceae	186801|Clostridia	C	Reductive dehalogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4_16,Fer4_7
HKD1_k127_6949018_10	1476973.JMMB01000007_gene1921	2.395e-178	561.0	COG3250@1|root,COG3250@2|Bacteria,1TSMY@1239|Firmicutes,24B54@186801|Clostridia,25TAR@186804|Peptostreptococcaceae	186801|Clostridia	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
HKD1_k127_6949018_12	445973.CLOBAR_01730	1.367e-165	531.0	COG0493@1|root,COG0493@2|Bacteria,1TR18@1239|Firmicutes,24A8Q@186801|Clostridia,25R9J@186804|Peptostreptococcaceae	186801|Clostridia	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HKD1_k127_6949018_5	1476973.JMMB01000007_gene1305	5.886e-222	692.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,25T63@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+-transporting oxaloacetate decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
HKD1_k127_6949018_25	1301100.HG529281_gene7013	1.038e-58	205.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,36KM8@31979|Clostridiaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HKD1_k127_6949018_26	1476973.JMMB01000007_gene1303	4.456e-38	146.0	29UMX@1|root,30FZG@2|Bacteria,1UEX9@1239|Firmicutes,25JWN@186801|Clostridia,25TQ2@186804|Peptostreptococcaceae	186801|Clostridia	S	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
HKD1_k127_6949018_1	1301100.HG529281_gene7011	5.637e-313	961.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,36E1X@31979|Clostridiaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HKD1_k127_6949018_22	1391646.AVSU01000043_gene1439	4.883e-82	273.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia,25T50@186804|Peptostreptococcaceae	186801|Clostridia	E	Glyoxalase-like domain	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
HKD1_k127_6949018_11	1476973.JMMB01000007_gene1300	4.812e-176	554.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia,25SGB@186804|Peptostreptococcaceae	186801|Clostridia	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
HKD1_k127_6949018_23	1292035.H476_1137	4.159e-70	239.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,25TDJ@186804|Peptostreptococcaceae	186801|Clostridia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
HKD1_k127_6949018_0	1292035.H476_1138	0.0	1022.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,25SH5@186804|Peptostreptococcaceae	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
HKD1_k127_6949018_2	1476973.JMMB01000007_gene1297	2.694e-281	869.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25SH7@186804|Peptostreptococcaceae	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HKD1_k127_6949018_3	1391646.AVSU01000043_gene1434	1.935e-246	766.0	COG2985@1|root,COG2985@2|Bacteria,1TT3J@1239|Firmicutes,24AC4@186801|Clostridia,25SYW@186804|Peptostreptococcaceae	186801|Clostridia	S	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex
HKD1_k127_6949018_19	1476973.JMMB01000007_gene1295	6.128e-127	411.0	COG0583@1|root,COG0583@2|Bacteria,1TST3@1239|Firmicutes,24CMV@186801|Clostridia,25T2T@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_6949018_17	1476973.JMMB01000007_gene1922	5.044e-142	455.0	2E45N@1|root,32Z1P@2|Bacteria,1VK6R@1239|Firmicutes,24UJB@186801|Clostridia,25QYN@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_6949018_21	272563.CD630_19680	1.405e-98	326.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia,25REA@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
HKD1_k127_6949018_20	293826.Amet_2923	7.444e-127	414.0	COG1835@1|root,COG1835@2|Bacteria,1V0J2@1239|Firmicutes,247YD@186801|Clostridia,36EK5@31979|Clostridiaceae	186801|Clostridia	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
HKD1_k127_7089480_3	1345695.CLSA_c00890	6.473e-86	285.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,36I6P@31979|Clostridiaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD1_k127_7089480_1	931276.Cspa_c00840	7.971e-161	509.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,36GMQ@31979|Clostridiaceae	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HKD1_k127_7089480_2	931276.Cspa_c00850	1.704e-113	367.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,36I75@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
HKD1_k127_7089480_0	1196322.A370_02401	6.784e-198	620.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,24FCV@186801|Clostridia,36FPR@31979|Clostridiaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_7091751_0	1391646.AVSU01000099_gene365	0.0	1588.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,25SIU@186804|Peptostreptococcaceae	186801|Clostridia	KL	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
HKD1_k127_7091751_2	272563.CD630_19050	7.901e-151	501.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,25TSY@186804|Peptostreptococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HKD1_k127_7091751_17	1476973.JMMB01000007_gene1883	8.663e-23	104.0	COG2856@1|root,COG2856@2|Bacteria,1VEWS@1239|Firmicutes,24R47@186801|Clostridia,25UDH@186804|Peptostreptococcaceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HKD1_k127_7091751_16	1301100.HG529274_gene1740	8.167e-23	103.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_7091751_21	1033737.CAEV01000076_gene556	4.266e-08	58.0	COG1476@1|root,COG1476@2|Bacteria,1UGHC@1239|Firmicutes,25NZB@186801|Clostridia,36NZP@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HKD1_k127_7091751_7	1292035.H476_1313	1.735e-87	296.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,25U42@186804|Peptostreptococcaceae	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	ANT,Bro-N
HKD1_k127_7091751_4	1292035.H476_1312	1.079e-134	438.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia	186801|Clostridia	L	YqaJ viral recombinase family	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
HKD1_k127_7091751_3	1476973.JMMB01000007_gene1881	1.861e-141	454.0	COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,24IDX@186801|Clostridia,25T25@186804|Peptostreptococcaceae	186801|Clostridia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HKD1_k127_7091751_5	1301100.HG529272_gene1705	1.233e-102	340.0	COG1484@1|root,COG1484@2|Bacteria,1V48P@1239|Firmicutes,24B2B@186801|Clostridia,36ER6@31979|Clostridiaceae	186801|Clostridia	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
HKD1_k127_7091751_18	1301100.HG529329_gene4472	9.532e-19	86.0	2DR5F@1|root,33A90@2|Bacteria,1VK5I@1239|Firmicutes,24UDD@186801|Clostridia,36N2M@31979|Clostridiaceae	186801|Clostridia	S	YvrJ protein family	-	-	-	-	-	-	-	-	-	-	-	-	YvrJ
HKD1_k127_7091751_10	1476973.JMMB01000007_gene1873	1.676e-32	127.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,25JCT@186801|Clostridia,25RZF@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
HKD1_k127_7091751_14	1476973.JMMB01000007_gene1872	5.21e-27	111.0	2A0AM@1|root,30NE1@2|Bacteria,1UF9X@1239|Firmicutes,252EI@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
HKD1_k127_7091751_15	1408254.T458_00035	1.385e-25	109.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,26ZQS@186822|Paenibacillaceae	91061|Bacilli	K	Cro Cl family transcriptional regulator	ygzD	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HKD1_k127_7091751_19	1347369.CCAD010000022_gene1659	1.83e-14	78.0	2DE5I@1|root,32U2P@2|Bacteria,1VAQ0@1239|Firmicutes,4HMJK@91061|Bacilli,1ZGWS@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7091751_6	1292035.H476_1261	1.485e-93	311.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase, LytC amidase family	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
HKD1_k127_7091751_22	641107.CDLVIII_1471	5.85e-05	47.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,36GBE@31979|Clostridiaceae	186801|Clostridia	K	Divergent AAA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
HKD1_k127_7091751_12	1151292.QEW_0731	1.298e-31	124.0	2DP9Y@1|root,3316Q@2|Bacteria,1VH0D@1239|Firmicutes,25DVC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7091751_8	1151292.QEW_0730	9.362e-52	185.0	COG3577@1|root,COG3577@2|Bacteria,1VAX6@1239|Firmicutes,24NDT@186801|Clostridia	186801|Clostridia	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
HKD1_k127_7091751_11	1476973.JMMB01000007_gene1866	1.169e-31	125.0	COG5566@1|root,COG5566@2|Bacteria,1VHWQ@1239|Firmicutes,24TPM@186801|Clostridia,25TYI@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_7091751_9	1301100.HG529316_gene495	8.03e-50	191.0	2BHXD@1|root,32C1G@2|Bacteria,1UQQV@1239|Firmicutes,24UNY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7091751_1	720554.Clocl_0280	3.809e-204	649.0	COG2865@1|root,COG2865@2|Bacteria,1TS3T@1239|Firmicutes,24CAJ@186801|Clostridia,3WKBI@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
HKD1_k127_7091751_13	1476973.JMMB01000007_gene1866	1.604e-31	125.0	COG5566@1|root,COG5566@2|Bacteria,1VHWQ@1239|Firmicutes,24TPM@186801|Clostridia,25TYI@186804|Peptostreptococcaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HKD1_k127_7123177_0	1476973.JMMB01000007_gene521	1.678e-254	787.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25SYX@186804|Peptostreptococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HKD1_k127_7123177_1	1476973.JMMB01000007_gene522	1.617e-155	493.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24GYI@186801|Clostridia,25S7J@186804|Peptostreptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
HKD1_k127_733101_3	1476973.JMMB01000007_gene2724	1.139e-259	803.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25QTC@186804|Peptostreptococcaceae	186801|Clostridia	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
HKD1_k127_733101_13	1476973.JMMB01000007_gene2725	2.793e-65	224.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,25RID@186804|Peptostreptococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HKD1_k127_733101_2	1476973.JMMB01000007_gene2726	1.943e-261	807.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25QXG@186804|Peptostreptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HKD1_k127_733101_16	1476973.JMMB01000007_gene2727	5.72e-51	181.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,25RK1@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HKD1_k127_733101_15	1151292.QEW_1539	4.675e-55	193.0	COG2868@1|root,COG2868@2|Bacteria,1VW8F@1239|Firmicutes,25CYG@186801|Clostridia,25UN3@186804|Peptostreptococcaceae	186801|Clostridia	J	Pfam:Peptidase_C108	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HKD1_k127_733101_14	1476973.JMMB01000007_gene2729	9.715e-58	201.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,25RS2@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HKD1_k127_733101_4	1476973.JMMB01000007_gene2730	6.533e-246	766.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,25QDS@186804|Peptostreptococcaceae	186801|Clostridia	J	S1 RNA binding domain protein	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
HKD1_k127_733101_9	1476973.JMMB01000007_gene2731	1.495e-120	390.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,25QM5@186804|Peptostreptococcaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
HKD1_k127_733101_1	1476973.JMMB01000007_gene2732	0.0	1200.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,25QYC@186804|Peptostreptococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HKD1_k127_733101_5	1476973.JMMB01000007_gene2733	2.118e-241	752.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,25R3X@186804|Peptostreptococcaceae	186801|Clostridia	C	Metallo-beta-lactamase superfamily	norV	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
HKD1_k127_733101_11	1151292.QEW_1532	9.087e-75	254.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,25RDH@186804|Peptostreptococcaceae	186801|Clostridia	G	MGS-like domain	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HKD1_k127_733101_6	1301100.HG529369_gene1464	2.702e-195	613.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,36EC8@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HKD1_k127_733101_17	1476973.JMMB01000007_gene2736	5.937e-46	167.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,25RSD@186804|Peptostreptococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
HKD1_k127_733101_7	1476973.JMMB01000007_gene2737	9.565e-152	482.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,25QSA@186804|Peptostreptococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HKD1_k127_733101_10	1476973.JMMB01000007_gene2738	5.626e-118	382.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,25R9G@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
HKD1_k127_733101_0	1476973.JMMB01000007_gene2739	0.0	1454.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25QP8@186804|Peptostreptococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HKD1_k127_733101_12	1476973.JMMB01000007_gene2740	1.272e-68	236.0	COG2891@1|root,COG2891@2|Bacteria,1W6D1@1239|Firmicutes,25JAG@186801|Clostridia,25RQ4@186804|Peptostreptococcaceae	186801|Clostridia	M	Rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HKD1_k127_733101_8	1476973.JMMB01000007_gene2741	3.288e-139	447.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,25R0B@186804|Peptostreptococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HKD1_k127_733101_18	1476973.JMMB01000007_gene2742	2.588e-21	93.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25QS2@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HKD1_k127_7351959_2	86416.Clopa_4784	2.725e-06	49.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,36WT8@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HKD1_k127_7351959_1	1476973.JMMB01000007_gene1511	4.373e-103	337.0	2F1CI@1|root,33UDD@2|Bacteria,1VV9U@1239|Firmicutes,24ZAH@186801|Clostridia,25RMU@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7351959_0	1476973.JMMB01000007_gene1510	1.079e-306	946.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,249NB@186801|Clostridia,25R27@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_20	1476973.JMMB01000007_gene1708	6.009e-92	304.0	COG2844@1|root,COG2844@2|Bacteria,1V2GH@1239|Firmicutes,24FRR@186801|Clostridia,25TDU@186804|Peptostreptococcaceae	186801|Clostridia	O	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HKD1_k127_7375560_6	1476973.JMMB01000007_gene1709	4.752e-201	635.0	2EZ6V@1|root,33SCU@2|Bacteria,1VQX5@1239|Firmicutes,24Z4Q@186801|Clostridia,25RAB@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_26	1476973.JMMB01000007_gene1710	8.337e-69	234.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,25QNR@186804|Peptostreptococcaceae	186801|Clostridia	KT	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_7375560_27	1476973.JMMB01000007_gene1710	1.383e-62	215.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,25QNR@186804|Peptostreptococcaceae	186801|Clostridia	KT	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_7375560_3	1476973.JMMB01000007_gene1711	2.434e-251	781.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,25QWK@186804|Peptostreptococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HKD1_k127_7375560_14	1476973.JMMB01000007_gene1712	4.453e-135	432.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,25QES@186804|Peptostreptococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA2	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HKD1_k127_7375560_4	1476973.JMMB01000007_gene1713	3.895e-248	768.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,25QJM@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HKD1_k127_7375560_10	1211817.CCAT010000048_gene2585	1.622e-162	520.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,249CD@186801|Clostridia,36E81@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HKD1_k127_7375560_17	1211817.CCAT010000048_gene2586	4.218e-115	374.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,36FD6@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_7375560_23	702450.CUW_0101	2.95e-78	267.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes,3VQZ7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
HKD1_k127_7375560_18	1211817.CCAT010000048_gene2588	2.684e-113	370.0	COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,24FRH@186801|Clostridia,36I9C@31979|Clostridiaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
HKD1_k127_7375560_29	1476973.JMMB01000007_gene1792	2.411e-60	211.0	COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,24I6N@186801|Clostridia,25TEN@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
HKD1_k127_7375560_25	1391646.AVSU01000044_gene1455	2.825e-76	258.0	COG0454@1|root,COG0456@2|Bacteria,1VHDN@1239|Firmicutes,24FXK@186801|Clostridia,25RYN@186804|Peptostreptococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HKD1_k127_7375560_30	1391646.AVSU01000015_gene3003	1.649e-57	201.0	2EJBW@1|root,33D30@2|Bacteria,1VDH3@1239|Firmicutes,24JQ8@186801|Clostridia,25TID@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HKD1_k127_7375560_39	1301100.HG529236_gene7276	8.79e-05	45.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,25KC5@186801|Clostridia,36NSP@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_7375560_11	1415774.U728_952	5.124e-160	509.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia,36EU7@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	fhuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HKD1_k127_7375560_9	1415774.U728_951	2.194e-166	527.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,24A8W@186801|Clostridia,36FH9@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HKD1_k127_7375560_7	195103.CPF_0809	1.669e-177	559.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36EF1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HKD1_k127_7375560_12	536233.CLO_1653	5.216e-151	479.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36DPF@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HKD1_k127_7375560_5	1292035.H476_2426	6.151e-216	677.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25S2V@186804|Peptostreptococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HKD1_k127_7375560_19	1476973.JMMB01000007_gene2453	9.124e-102	336.0	28I7X@1|root,2Z8AS@2|Bacteria,1UTKU@1239|Firmicutes,24AYU@186801|Clostridia,25SAY@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_38	1262449.CP6013_0546	9.175e-09	56.0	28NQ2@1|root,2ZBPT@2|Bacteria,1V2UY@1239|Firmicutes,24JMI@186801|Clostridia,36J1Z@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_33	1499683.CCFF01000016_gene879	3.41e-45	166.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,25KC5@186801|Clostridia,36NSP@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HKD1_k127_7375560_8	1410653.JHVC01000007_gene442	5.608e-176	558.0	COG1852@1|root,COG1852@2|Bacteria,1UZ1X@1239|Firmicutes,24A38@186801|Clostridia,36EPT@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
HKD1_k127_7375560_2	649747.HMPREF0083_01523	4.585e-275	851.0	COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli,26U17@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0061 (SELO) family	M1-1044	-	-	-	-	-	-	-	-	-	-	-	UPF0061
HKD1_k127_7375560_37	1169144.KB910930_gene1615	3.28e-11	64.0	2E9KQ@1|root,333TF@2|Bacteria,1VHNG@1239|Firmicutes,4HQR9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_36	1216932.CM240_1021	3.02e-12	68.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,36E0Y@31979|Clostridiaceae	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
HKD1_k127_7375560_15	247490.KSU1_C0714	9.649e-133	451.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
HKD1_k127_7375560_40	1476973.JMMB01000007_gene2168	0.0001078	46.0	COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae	186801|Clostridia	L	DnaB-like helicase N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
HKD1_k127_7375560_22	247490.KSU1_C0714	1.497e-83	299.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
HKD1_k127_7375560_28	1415774.U728_3170	1.54e-62	220.0	2AHVT@1|root,3188J@2|Bacteria,1V8V5@1239|Firmicutes,24FT6@186801|Clostridia,36IAB@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7375560_31	1410653.JHVC01000007_gene603	2.565e-54	191.0	COG4262@1|root,COG4262@2|Bacteria,1UHSI@1239|Firmicutes,24C6V@186801|Clostridia,36VWU@31979|Clostridiaceae	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
HKD1_k127_7375560_35	1128398.Curi_c27610	5.954e-14	71.0	COG4262@1|root,COG4262@2|Bacteria,1UHSI@1239|Firmicutes,24C6V@186801|Clostridia	186801|Clostridia	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
HKD1_k127_7375560_16	1476973.JMMB01000007_gene2959	9.466e-126	408.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,24JHK@186801|Clostridia,25U71@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HKD1_k127_7375560_0	1476973.JMMB01000007_gene2958	0.0	1141.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25S5F@186804|Peptostreptococcaceae	186801|Clostridia	C	Prismane/CO dehydrogenase family	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
HKD1_k127_7375560_13	1476973.JMMB01000007_gene2957	9.823e-144	458.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,25QN6@186804|Peptostreptococcaceae	186801|Clostridia	D	Anion-transporting ATPase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
HKD1_k127_7375560_32	349161.Dred_0079	6.643e-50	196.0	28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,2487N@186801|Clostridia,25ZXS@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM sporulation peptidase YabG	yabG	-	-	ko:K06436	-	-	-	-	ko00000	-	-	-	Peptidase_U57
HKD1_k127_7375560_34	1476973.JMMB01000007_gene1421	2.714e-35	152.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25R4H@186804|Peptostreptococcaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
HKD1_k127_7375560_24	1476973.JMMB01000007_gene1424	5.437e-77	259.0	COG1285@1|root,COG1285@2|Bacteria,1UTK5@1239|Firmicutes,253E3@186801|Clostridia	186801|Clostridia	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	MgtC
HKD1_k127_7375560_1	1476973.JMMB01000007_gene1370	1e-323	1000.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SVV@186804|Peptostreptococcaceae	186801|Clostridia	T	Cache 3/Cache 2 fusion domain	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,PAS_9,dCache_1
HKD1_k127_7375560_41	290402.Cbei_2088	0.000392	44.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,249B1@186801|Clostridia,36GGP@31979|Clostridiaceae	186801|Clostridia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
HKD1_k127_7375560_21	290402.Cbei_2089	3.963e-87	289.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,36GVM@31979|Clostridiaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K15600	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
HKD1_k127_7427416_1	1301100.HG529440_gene4794	1.554e-198	624.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
HKD1_k127_7427416_0	1476973.JMMB01000007_gene117	0.0	1449.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25QKN@186804|Peptostreptococcaceae	186801|Clostridia	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
HKD1_k127_7427416_2	1476973.JMMB01000007_gene116	4.712e-95	313.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,25R8P@186804|Peptostreptococcaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HKD1_k127_7529494_0	1476973.JMMB01000007_gene2704	0.0	1137.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25S1C@186804|Peptostreptococcaceae	186801|Clostridia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
HKD1_k127_7529494_1	1476973.JMMB01000007_gene2705	0.0	1064.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,25QGF@186804|Peptostreptococcaceae	186801|Clostridia	J	Elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
HKD1_k127_7529494_2	1476973.JMMB01000007_gene2706	8.939e-256	793.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,25R1B@186804|Peptostreptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
HKD1_k127_7529494_3	1476973.JMMB01000007_gene2707	4.271e-183	575.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,25R6K@186804|Peptostreptococcaceae	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HKD1_k127_7529494_4	1476973.JMMB01000007_gene2708	1.714e-65	226.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,25RI8@186804|Peptostreptococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HKD1_k127_7564381_6	293826.Amet_2923	1.147e-95	321.0	COG1835@1|root,COG1835@2|Bacteria,1V0J2@1239|Firmicutes,247YD@186801|Clostridia,36EK5@31979|Clostridiaceae	186801|Clostridia	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
HKD1_k127_7564381_4	1292035.H476_1520	6.416e-113	372.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HKD1_k127_7564381_3	1476973.JMMB01000007_gene1846	3.893e-133	428.0	2E0AV@1|root,32VY6@2|Bacteria,1VH1N@1239|Firmicutes,256XQ@186801|Clostridia,25S3B@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7564381_2	1476973.JMMB01000007_gene1847	1.842e-172	545.0	COG1106@1|root,COG1106@2|Bacteria,1V7XW@1239|Firmicutes,25NZG@186801|Clostridia,25SKR@186804|Peptostreptococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
HKD1_k127_7564381_10	1131730.BAVI_05859	9.941e-57	200.0	COG0494@1|root,COG0494@2|Bacteria,1V6VE@1239|Firmicutes,4ISB4@91061|Bacilli,1ZRD9@1386|Bacillus	91061|Bacilli	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HKD1_k127_7564381_12	1321778.HMPREF1982_04644	1.229e-38	160.0	2DMAN@1|root,32DSV@2|Bacteria,1V8JH@1239|Firmicutes,24MCY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
HKD1_k127_7564381_13	332101.JIBU02000043_gene1517	4.618e-07	53.0	COG0823@1|root,COG2247@1|root,COG0823@2|Bacteria,COG2247@2|Bacteria,1UJHC@1239|Firmicutes,25F38@186801|Clostridia,36FKG@31979|Clostridiaceae	186801|Clostridia	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
HKD1_k127_7564381_11	1321778.HMPREF1982_04644	4.362e-39	160.0	2DMAN@1|root,32DSV@2|Bacteria,1V8JH@1239|Firmicutes,24MCY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
HKD1_k127_7564381_7	1476973.JMMB01000007_gene1550	5.068e-95	315.0	COG3758@1|root,COG3758@2|Bacteria,1VH52@1239|Firmicutes,24P8J@186801|Clostridia,25TMJ@186804|Peptostreptococcaceae	186801|Clostridia	S	HutD	-	-	-	-	-	-	-	-	-	-	-	-	HutD
HKD1_k127_7564381_0	1121324.CLIT_10c01770	1e-323	997.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SVV@186804|Peptostreptococcaceae	186801|Clostridia	T	Cache 3/Cache 2 fusion domain	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,dCache_1
HKD1_k127_7564381_5	86416.Clopa_0120	1.577e-109	357.0	COG1304@1|root,COG1304@2|Bacteria,1TUS7@1239|Firmicutes,248F9@186801|Clostridia,36E1J@31979|Clostridiaceae	186801|Clostridia	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7564381_1	290402.Cbei_2091	1.828e-177	559.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,36FHT@31979|Clostridiaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
HKD1_k127_7564381_9	324057.Pjdr2_5405	2.759e-65	231.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,26RBB@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	ssuC	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
HKD1_k127_7564381_8	1196322.A370_03287	3.789e-75	253.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,36GVM@31979|Clostridiaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K15600	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
HKD1_k127_7564690_19	1301100.HG529359_gene2140	1.977e-25	108.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia,36DJC@31979|Clostridiaceae	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
HKD1_k127_7564690_16	1476973.JMMB01000007_gene2557	3.328e-48	178.0	29UPP@1|root,30G1D@2|Bacteria,1UF0Z@1239|Firmicutes,25K1H@186801|Clostridia,25U59@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	-
HKD1_k127_7564690_13	1499684.CCNP01000015_gene401	4.703e-68	239.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,36FHM@31979|Clostridiaceae	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
HKD1_k127_7564690_8	1476973.JMMB01000007_gene2559	1.134e-124	404.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,25SHN@186804|Peptostreptococcaceae	186801|Clostridia	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
HKD1_k127_7564690_6	1476973.JMMB01000007_gene2560	1.702e-166	526.0	COG4786@1|root,COG4786@2|Bacteria,1TRA2@1239|Firmicutes,25EBP@186801|Clostridia,25SR6@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD1_k127_7564690_11	1476973.JMMB01000007_gene2561	9.011e-79	267.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia,25T95@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar hook capping protein - N-terminal region	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
HKD1_k127_7564690_9	1476973.JMMB01000007_gene2562	3.582e-111	373.0	COG3144@1|root,COG3144@2|Bacteria,1VI6B@1239|Firmicutes,24CPZ@186801|Clostridia,25TTD@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar hook-length control protein FliK	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
HKD1_k127_7564690_14	1476973.JMMB01000007_gene2563	6.016e-51	184.0	COG2882@1|root,COG2882@2|Bacteria,1VZYW@1239|Firmicutes,24NWG@186801|Clostridia,25TN4@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar FliJ protein	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
HKD1_k127_7564690_2	1476973.JMMB01000007_gene2564	5.464e-259	801.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,25T1A@186804|Peptostreptococcaceae	186801|Clostridia	NU	ATP synthase alpha/beta family, beta-barrel domain	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HKD1_k127_7564690_15	1499684.CCNP01000015_gene394	8.478e-49	184.0	COG1317@1|root,COG1317@2|Bacteria,1V6VN@1239|Firmicutes,25IJ7@186801|Clostridia,36IHV@31979|Clostridiaceae	186801|Clostridia	NU	bacterial-type flagellum organization	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
HKD1_k127_7564690_4	1476973.JMMB01000007_gene2566	1.153e-191	602.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,25SNF@186804|Peptostreptococcaceae	186801|Clostridia	N	FliG C-terminal domain	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
HKD1_k127_7564690_3	1476973.JMMB01000007_gene2567	4.402e-235	736.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia,25SB9@186804|Peptostreptococcaceae	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
HKD1_k127_7564690_18	1476973.JMMB01000007_gene2568	3.698e-32	128.0	COG1677@1|root,COG1677@2|Bacteria,1UEZR@1239|Firmicutes,25JZX@186801|Clostridia,25U1A@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
HKD1_k127_7564690_12	1476973.JMMB01000007_gene2569	1.983e-69	236.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia,25T96@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
HKD1_k127_7564690_17	1476973.JMMB01000007_gene2570	4.284e-47	171.0	COG1815@1|root,COG1815@2|Bacteria,1UEBI@1239|Firmicutes,25J75@186801|Clostridia,25TQC@186804|Peptostreptococcaceae	186801|Clostridia	N	Flagella basal body rod protein	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
HKD1_k127_7564690_7	1292035.H476_1771	6.414e-147	473.0	COG0463@1|root,COG0790@1|root,COG0463@2|Bacteria,COG0790@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,TPR_2,TPR_7,TPR_8
HKD1_k127_7564690_5	1292035.H476_3004	8.383e-186	593.0	COG2755@1|root,COG2755@2|Bacteria,1V5CJ@1239|Firmicutes,24IWV@186801|Clostridia	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7564690_10	1301100.HG529359_gene2156	3.897e-89	298.0	COG0500@1|root,COG0500@2|Bacteria,1V1KE@1239|Firmicutes,24UQ2@186801|Clostridia	186801|Clostridia	Q	PFAM Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HKD1_k127_7564690_1	1301100.HG529359_gene2157	1.155e-296	919.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,36MHC@31979|Clostridiaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HKD1_k127_7564690_0	1476973.JMMB01000007_gene2578	3.75e-304	948.0	COG0463@1|root,COG4783@1|root,COG0463@2|Bacteria,COG4783@2|Bacteria,1TRCN@1239|Firmicutes,25E6P@186801|Clostridia,25SJU@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
HKD1_k127_7564690_20	1301100.HG529359_gene2160	3.682e-06	48.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
HKD1_k127_7621211_34	1229172.JQFA01000004_gene874	4.495e-96	327.0	COG0124@1|root,COG0124@2|Bacteria,1G066@1117|Cyanobacteria,1H8BY@1150|Oscillatoriales	1117|Cyanobacteria	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HKD1_k127_7621211_2	1301100.HG529431_gene1848	0.0	1275.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,36E2T@31979|Clostridiaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HKD1_k127_7621211_25	1476973.JMMB01000007_gene102	2.848e-156	494.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,25QD1@186804|Peptostreptococcaceae	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HKD1_k127_7621211_33	1476973.JMMB01000007_gene101	6.748e-103	336.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,25QDT@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
HKD1_k127_7621211_18	1476973.JMMB01000007_gene100	6.246e-174	546.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25R4Y@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HKD1_k127_7621211_15	1476973.JMMB01000007_gene3262	2.019e-182	580.0	COG3087@1|root,COG3087@2|Bacteria,1V30Z@1239|Firmicutes,25J52@186801|Clostridia,25QYA@186804|Peptostreptococcaceae	186801|Clostridia	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7621211_10	1476973.JMMB01000007_gene98	8.93e-209	652.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,25SM0@186804|Peptostreptococcaceae	186801|Clostridia	E	Peptidase family M28	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HKD1_k127_7621211_29	1476973.JMMB01000007_gene97	9.476e-125	404.0	2C02Q@1|root,33SMQ@2|Bacteria,1VRCC@1239|Firmicutes,24XZ8@186801|Clostridia,25R8J@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7621211_6	1476973.JMMB01000007_gene3259	6.788e-278	856.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,25R68@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HKD1_k127_7621211_20	1476973.JMMB01000007_gene3258	8.263e-167	526.0	COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,25CKT@186801|Clostridia,25QE2@186804|Peptostreptococcaceae	186801|Clostridia	F	operon repressor	purR	-	-	ko:K09685	-	-	-	-	ko00000,ko03000	-	-	-	Pribosyltran,PuR_N
HKD1_k127_7621211_42	1476973.JMMB01000007_gene3257	5.447e-51	181.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,25TJJ@186804|Peptostreptococcaceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
HKD1_k127_7621211_8	1476973.JMMB01000007_gene3256	8.507e-272	839.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,25QZH@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
HKD1_k127_7621211_13	1476973.JMMB01000007_gene3255	4.567e-194	606.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25QGP@186804|Peptostreptococcaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
HKD1_k127_7621211_47	1301100.HG529431_gene1824	2.976e-27	116.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,25EXE@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
HKD1_k127_7621211_17	935948.KE386495_gene2133	1.113e-176	569.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
HKD1_k127_7621211_19	1292035.H476_3212	4.618e-167	533.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25SU9@186804|Peptostreptococcaceae	186801|Clostridia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HKD1_k127_7621211_27	1292035.H476_3211	2.942e-129	430.0	COG4972@1|root,COG4972@2|Bacteria,1UD8E@1239|Firmicutes,25HW6@186801|Clostridia,25SK6@186804|Peptostreptococcaceae	186801|Clostridia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
HKD1_k127_7621211_40	1301100.HG529431_gene1818	1.634e-60	220.0	COG3167@1|root,COG3167@2|Bacteria	2|Bacteria	NU	carbon utilization	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
HKD1_k127_7621211_49	272563.CD630_35080	3.036e-12	78.0	297EM@1|root,2ZUN2@2|Bacteria,1W546@1239|Firmicutes,256QR@186801|Clostridia,25U54@186804|Peptostreptococcaceae	186801|Clostridia	S	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
HKD1_k127_7621211_48	272563.CD630_35070	6.85e-17	86.0	COG4967@1|root,COG4967@2|Bacteria,1W6HW@1239|Firmicutes	1239|Firmicutes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HKD1_k127_7621211_50	1476973.JMMB01000007_gene3246	5.79e-07	61.0	2BEZT@1|root,328RG@2|Bacteria,1UUPT@1239|Firmicutes,257DU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7621211_14	1301100.HG529431_gene1815	1.694e-183	578.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,36E42@31979|Clostridiaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HKD1_k127_7621211_26	1476973.JMMB01000007_gene3244	5.252e-131	421.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,25T6N@186804|Peptostreptococcaceae	186801|Clostridia	NOU	Bacterial Peptidase A24 N-terminal domain	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HKD1_k127_7621211_36	1476973.JMMB01000007_gene3243	1.023e-91	305.0	COG1989@1|root,COG1989@2|Bacteria,1VVXC@1239|Firmicutes,25077@186801|Clostridia,25RJW@186804|Peptostreptococcaceae	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
HKD1_k127_7621211_32	1301100.HG529431_gene1811	3.882e-111	360.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,36G0N@31979|Clostridiaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HKD1_k127_7621211_0	1476973.JMMB01000007_gene3241	0.0	2066.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,25QCA@186804|Peptostreptococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HKD1_k127_7621211_23	1476973.JMMB01000007_gene3240	3.075e-158	504.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
HKD1_k127_7621211_35	1476973.JMMB01000007_gene3239	5.346e-93	307.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,25QHK@186804|Peptostreptococcaceae	186801|Clostridia	K	SpoVT / AbrB like domain	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HKD1_k127_7621211_4	1476973.JMMB01000007_gene3238	1.153e-290	898.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25QTE@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
HKD1_k127_7621211_5	1476973.JMMB01000007_gene3237	3.407e-289	891.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,25R1D@186804|Peptostreptococcaceae	186801|Clostridia	S	Tetrapyrrole methylase	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
HKD1_k127_7621211_41	1301100.HG529431_gene1803	2.658e-52	186.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,36KID@31979|Clostridiaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HKD1_k127_7621211_45	1476973.JMMB01000007_gene3235	1.454e-36	139.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,25RR5@186804|Peptostreptococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
HKD1_k127_7621211_43	1476973.JMMB01000007_gene3234	5.379e-41	153.0	29UMP@1|root,30FZ7@2|Bacteria,1UEWZ@1239|Firmicutes,25JWD@186801|Clostridia,25TPC@186804|Peptostreptococcaceae	186801|Clostridia	S	YabP family	-	-	-	-	-	-	-	-	-	-	-	-	YabP
HKD1_k127_7621211_38	1476973.JMMB01000007_gene3233	6.799e-84	280.0	2EFTM@1|root,339JQ@2|Bacteria,1VKCW@1239|Firmicutes,25JB2@186801|Clostridia,25RTI@186804|Peptostreptococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
HKD1_k127_7621211_46	1476973.JMMB01000007_gene3232	4.973e-34	132.0	COG2919@1|root,COG2919@2|Bacteria,1W0RR@1239|Firmicutes,25N5B@186801|Clostridia,25S0I@186804|Peptostreptococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HKD1_k127_7621211_24	1476973.JMMB01000007_gene3231	2.774e-157	500.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,24AVM@186801|Clostridia,25QDA@186804|Peptostreptococcaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
HKD1_k127_7621211_1	1476973.JMMB01000007_gene3230	0.0	1336.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,25QGW@186804|Peptostreptococcaceae	186801|Clostridia	KT	Serine/threonine phosphatases, family 2C, catalytic domain	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HKD1_k127_7621211_3	1476973.JMMB01000007_gene3229	0.0	1085.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,25QXZ@186804|Peptostreptococcaceae	186801|Clostridia	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HKD1_k127_7621211_16	1476973.JMMB01000007_gene3228	1.683e-177	557.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,25QH5@186804|Peptostreptococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HKD1_k127_7621211_12	1476973.JMMB01000007_gene3226	9.598e-207	644.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,249PW@186801|Clostridia,25QUF@186804|Peptostreptococcaceae	186801|Clostridia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
HKD1_k127_7621211_7	1301100.HG529431_gene1791	2.182e-277	859.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,36EED@31979|Clostridiaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HKD1_k127_7621211_44	1476973.JMMB01000007_gene3224	8.016e-37	139.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,25RP0@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HKD1_k127_7621211_31	1301100.HG529431_gene1789	1.222e-117	379.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,36DU8@31979|Clostridiaceae	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
HKD1_k127_7621211_21	1301100.HG529431_gene1788	2.492e-161	511.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,36FM3@31979|Clostridiaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
HKD1_k127_7621211_22	1476973.JMMB01000007_gene3221	2.321e-160	507.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,25RFP@186804|Peptostreptococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
HKD1_k127_7621211_9	1476973.JMMB01000007_gene3220	3.187e-213	664.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25QD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HKD1_k127_7621211_30	1476973.JMMB01000007_gene3219	1.202e-121	393.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25S68@186804|Peptostreptococcaceae	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HKD1_k127_7621211_11	1476973.JMMB01000007_gene3218	2.799e-207	647.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,25QUU@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HKD1_k127_7621211_37	1476973.JMMB01000007_gene3217	1.245e-91	302.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25RC3@186804|Peptostreptococcaceae	186801|Clostridia	G	isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HKD1_k127_7621211_28	1476973.JMMB01000007_gene3216	6.012e-126	404.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25QEK@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HKD1_k127_7621211_39	272563.CD630_34770	1.472e-83	278.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia	186801|Clostridia	F	cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HKD1_k127_7850249_4	1301100.HG529428_gene1874	1.201e-62	217.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,36DUN@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HKD1_k127_7850249_3	1292035.H476_0793	4.161e-86	291.0	2EXP9@1|root,33QYZ@2|Bacteria,1VSFB@1239|Firmicutes,24B5B@186801|Clostridia,25TAU@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7850249_2	1292035.H476_0792	6.017e-99	333.0	2EWTR@1|root,33Q5A@2|Bacteria,1VRV8@1239|Firmicutes,24EZ9@186801|Clostridia,25T9Z@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HKD1_k127_7850249_1	1292035.H476_0791	8.676e-121	391.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,25SKP@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HKD1_k127_7850249_0	1391646.AVSU01000049_gene1639	2.265e-184	587.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,25SAZ@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
## 3019 queries scanned
## Total time (seconds): 161.44443559646606
## Rate: 18.70 q/s